Saccharomyces cerevisiae

39 known processes

AKL1 (YBR059C)

Akl1p

AKL1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytoskeleton organization GO:0007010 230 0.971
vesicle mediated transport GO:0016192 335 0.957
regulation of cell communication GO:0010646 124 0.834
Human
single organism signaling GO:0044700 208 0.786
Human
phosphorylation GO:0016310 291 0.755
regulation of receptor mediated endocytosis GO:0048259 4 0.736
Human Rat Fly
endocytosis GO:0006897 90 0.691
establishment of protein localization GO:0045184 367 0.641
signal transduction GO:0007165 208 0.604
Human
membrane organization GO:0061024 276 0.600
cell communication GO:0007154 345 0.557
Human
secretion by cell GO:0032940 50 0.541
regulation of signaling GO:0023051 119 0.530
Human
regulation of endocytosis GO:0030100 17 0.525
signaling GO:0023052 208 0.521
Human
regulation of response to stimulus GO:0048583 157 0.479
Human
regulation of localization GO:0032879 127 0.467
protein phosphorylation GO:0006468 197 0.453
protein complex biogenesis GO:0070271 314 0.408
regulation of cellular component organization GO:0051128 334 0.400
protein transport GO:0015031 345 0.386
regulation of protein localization GO:0032880 62 0.379
Human
dna replication GO:0006260 147 0.360
regulation of signal transduction GO:0009966 114 0.345
Human
small gtpase mediated signal transduction GO:0007264 36 0.343
organophosphate metabolic process GO:0019637 597 0.336
protein complex assembly GO:0006461 302 0.327
actin filament based process GO:0030029 104 0.259
positive regulation of transport GO:0051050 32 0.242
developmental process GO:0032502 261 0.239
Mouse Fly
positive regulation of signaling GO:0023056 20 0.232
Human
negative regulation of cellular biosynthetic process GO:0031327 312 0.227
regulation of intracellular signal transduction GO:1902531 78 0.223
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.218
membrane lipid metabolic process GO:0006643 67 0.201
anatomical structure development GO:0048856 160 0.199
Mouse Fly
intracellular protein transport GO:0006886 319 0.187
regulation of molecular function GO:0065009 320 0.187
Mouse
single organism membrane organization GO:0044802 275 0.179
autophagy GO:0006914 106 0.170
positive regulation of macromolecule metabolic process GO:0010604 394 0.160
regulation of cell growth GO:0001558 29 0.156
single organism developmental process GO:0044767 258 0.145
Mouse Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.143
positive regulation of phosphorus metabolic process GO:0010562 147 0.143
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.139
actin filament organization GO:0007015 56 0.137
Yeast
positive regulation of endocytosis GO:0045807 12 0.136
positive regulation of cell communication GO:0010647 28 0.136
Human
regulation of transport GO:0051049 85 0.135
actin cytoskeleton organization GO:0030036 100 0.133
guanosine containing compound metabolic process GO:1901068 111 0.131
multi organism process GO:0051704 233 0.129
secretion GO:0046903 50 0.124
cellular protein complex assembly GO:0043623 209 0.123
mitotic cell cycle process GO:1903047 294 0.118
intracellular signal transduction GO:0035556 112 0.116
endomembrane system organization GO:0010256 74 0.114
regulation of dna dependent dna replication GO:0090329 37 0.110
cellular response to pheromone GO:0071444 88 0.110
regulation of phosphorus metabolic process GO:0051174 230 0.109
regulation of dna replication GO:0006275 51 0.106
carbohydrate derivative metabolic process GO:1901135 549 0.104
regulation of proteolysis GO:0030162 44 0.104
glycerolipid biosynthetic process GO:0045017 71 0.103
cell differentiation GO:0030154 161 0.103
Fly
negative regulation of biosynthetic process GO:0009890 312 0.102
positive regulation of response to stimulus GO:0048584 37 0.098
Human
cortical actin cytoskeleton organization GO:0030866 11 0.091
Yeast
positive regulation of signal transduction GO:0009967 20 0.087
Human
carbohydrate metabolic process GO:0005975 252 0.085
membrane budding GO:0006900 22 0.083
reproduction of a single celled organism GO:0032505 191 0.082
mitotic cytokinesis GO:0000281 58 0.082
negative regulation of dna metabolic process GO:0051053 36 0.082
cellular homeostasis GO:0019725 138 0.082
sphingolipid metabolic process GO:0006665 41 0.081
positive regulation of catalytic activity GO:0043085 178 0.081
chromatin silencing at telomere GO:0006348 84 0.081
positive regulation of phosphate metabolic process GO:0045937 147 0.080
peptidyl amino acid modification GO:0018193 116 0.079
establishment of cell polarity GO:0030010 64 0.079
positive regulation of cellular biosynthetic process GO:0031328 336 0.078
nucleocytoplasmic transport GO:0006913 163 0.077
asexual reproduction GO:0019954 48 0.072
proteolysis GO:0006508 268 0.072
mitotic cell cycle GO:0000278 306 0.071
positive regulation of transcription dna templated GO:0045893 286 0.070
anatomical structure morphogenesis GO:0009653 160 0.069
Fly
sexual reproduction GO:0019953 216 0.068
cellular response to organic substance GO:0071310 159 0.067
regulation of small gtpase mediated signal transduction GO:0051056 47 0.067
regulation of phosphate metabolic process GO:0019220 230 0.067
conjugation GO:0000746 107 0.066
cortical cytoskeleton organization GO:0030865 11 0.064
Yeast
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.064
regulation of microtubule based process GO:0032886 32 0.063
cellular developmental process GO:0048869 191 0.063
Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.063
regulation of growth GO:0040008 50 0.063
regulation of biological quality GO:0065008 391 0.062
Human
regulation of catalytic activity GO:0050790 307 0.060
Mouse
negative regulation of cellular metabolic process GO:0031324 407 0.060
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.055
macromolecular complex disassembly GO:0032984 80 0.055
regulation of cell cycle GO:0051726 195 0.053
nuclear division GO:0000280 263 0.053
guanosine containing compound catabolic process GO:1901069 109 0.053
positive regulation of nucleic acid templated transcription GO:1903508 286 0.053
positive regulation of hydrolase activity GO:0051345 112 0.052
purine ribonucleoside catabolic process GO:0046130 330 0.050
positive regulation of biosynthetic process GO:0009891 336 0.049
response to pheromone GO:0019236 92 0.049
nucleoside triphosphate metabolic process GO:0009141 364 0.048
signal transduction by phosphorylation GO:0023014 31 0.047
carbohydrate transport GO:0008643 33 0.047
chemical homeostasis GO:0048878 137 0.047
regulation of protein metabolic process GO:0051246 237 0.047
single organism cellular localization GO:1902580 375 0.047
positive regulation of gtp catabolic process GO:0033126 80 0.047
positive regulation of mapk cascade GO:0043410 10 0.046
nucleobase containing compound catabolic process GO:0034655 479 0.046
cell division GO:0051301 205 0.046
Fly
nucleoside phosphate metabolic process GO:0006753 458 0.045
cell growth GO:0016049 89 0.045
positive regulation of nucleotide catabolic process GO:0030813 97 0.045
regulation of response to stress GO:0080134 57 0.044
positive regulation of phosphorylation GO:0042327 33 0.043
positive regulation of molecular function GO:0044093 185 0.043
purine containing compound catabolic process GO:0072523 332 0.043
regulation of ras protein signal transduction GO:0046578 47 0.043
protein catabolic process GO:0030163 221 0.042
single organism catabolic process GO:0044712 619 0.042
cellular protein catabolic process GO:0044257 213 0.042
negative regulation of transcription dna templated GO:0045892 258 0.042
homeostatic process GO:0042592 227 0.041
regulation of multi organism process GO:0043900 20 0.041
cellular lipid metabolic process GO:0044255 229 0.040
glycerolipid metabolic process GO:0046486 108 0.040
gene silencing GO:0016458 151 0.040
metal ion homeostasis GO:0055065 79 0.039
regulation of cellular localization GO:0060341 50 0.039
cellular response to dna damage stimulus GO:0006974 287 0.039
cellular nitrogen compound catabolic process GO:0044270 494 0.039
sporulation GO:0043934 132 0.039
dna dependent dna replication GO:0006261 115 0.038
organelle localization GO:0051640 128 0.038
purine ribonucleotide metabolic process GO:0009150 372 0.038
receptor metabolic process GO:0043112 8 0.037
negative regulation of cell communication GO:0010648 33 0.036
ras protein signal transduction GO:0007265 29 0.036
cellular response to chemical stimulus GO:0070887 315 0.036
cellular amide metabolic process GO:0043603 59 0.036
protein targeting GO:0006605 272 0.036
positive regulation of ras gtpase activity GO:0032320 41 0.036
mapk cascade GO:0000165 30 0.036
protein localization to membrane GO:0072657 102 0.035
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.035
aromatic compound catabolic process GO:0019439 491 0.035
nucleoside metabolic process GO:0009116 394 0.035
establishment or maintenance of cell polarity GO:0007163 96 0.034
positive regulation of cellular protein metabolic process GO:0032270 89 0.034
phospholipid transport GO:0015914 23 0.034
positive regulation of cell death GO:0010942 3 0.034
positive regulation of purine nucleotide catabolic process GO:0033123 97 0.033
positive regulation of purine nucleotide metabolic process GO:1900544 100 0.033
gtp catabolic process GO:0006184 107 0.033
cellular macromolecule catabolic process GO:0044265 363 0.032
reproductive process GO:0022414 248 0.032
regulation of chromatin silencing at telomere GO:0031938 27 0.032
cellular component disassembly GO:0022411 86 0.032
negative regulation of microtubule polymerization or depolymerization GO:0031111 7 0.031
actin cortical patch organization GO:0044396 10 0.031
Yeast
cation transport GO:0006812 166 0.031
positive regulation of cytoplasmic transport GO:1903651 4 0.031
ribonucleoside catabolic process GO:0042454 332 0.030
regulation of purine nucleotide catabolic process GO:0033121 106 0.030
carbohydrate derivative catabolic process GO:1901136 339 0.030
protein localization to vacuole GO:0072665 92 0.030
endosomal transport GO:0016197 86 0.030
death GO:0016265 30 0.029
sporulation resulting in formation of a cellular spore GO:0030435 129 0.029
positive regulation of gtpase activity GO:0043547 80 0.029
regulation of mitotic cell cycle GO:0007346 107 0.029
protein maturation GO:0051604 76 0.029
regulation of gtpase activity GO:0043087 84 0.029
protein localization to organelle GO:0033365 337 0.029
positive regulation of rna metabolic process GO:0051254 294 0.029
negative regulation of rna metabolic process GO:0051253 262 0.028
late endosome to vacuole transport via multivesicular body sorting pathway GO:0032511 26 0.028
meiotic cell cycle process GO:1903046 229 0.028
nucleoside phosphate catabolic process GO:1901292 331 0.028
regulation of nucleotide catabolic process GO:0030811 106 0.028
positive regulation of nucleotide metabolic process GO:0045981 101 0.028
regulation of pseudohyphal growth GO:2000220 18 0.028
reproductive process in single celled organism GO:0022413 145 0.028
regulation of microtubule polymerization GO:0031113 14 0.027
actin cortical patch assembly GO:0000147 9 0.027
Yeast
regulation of vesicle mediated transport GO:0060627 39 0.027
establishment of organelle localization GO:0051656 96 0.027
microtubule cytoskeleton organization GO:0000226 109 0.027
sphingolipid biosynthetic process GO:0030148 29 0.027
regulation of cell size GO:0008361 30 0.027
positive regulation of secretion by cell GO:1903532 2 0.026
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.026
negative regulation of macromolecule metabolic process GO:0010605 375 0.026
energy derivation by oxidation of organic compounds GO:0015980 125 0.026
positive regulation of intracellular protein transport GO:0090316 3 0.026
glycerophospholipid metabolic process GO:0006650 98 0.026
growth GO:0040007 157 0.025
phospholipid metabolic process GO:0006644 125 0.025
fungal type cell wall organization GO:0031505 145 0.025
ion transport GO:0006811 274 0.025
nucleotide catabolic process GO:0009166 330 0.025
heterocycle catabolic process GO:0046700 494 0.025
lipid metabolic process GO:0006629 269 0.025
regulation of nucleotide metabolic process GO:0006140 110 0.025
macromolecule catabolic process GO:0009057 383 0.024
negative regulation of cellular component organization GO:0051129 109 0.024
positive regulation of nucleocytoplasmic transport GO:0046824 4 0.024
single organism membrane fusion GO:0044801 71 0.024
response to external stimulus GO:0009605 158 0.023
negative regulation of phosphorylation GO:0042326 28 0.023
microtubule polymerization GO:0046785 30 0.023
amine metabolic process GO:0009308 51 0.023
regulation of ras gtpase activity GO:0032318 41 0.023
regulation of dna metabolic process GO:0051052 100 0.023
nucleobase containing small molecule metabolic process GO:0055086 491 0.023
covalent chromatin modification GO:0016569 119 0.022
positive regulation of intracellular transport GO:0032388 4 0.022
purine ribonucleotide catabolic process GO:0009154 327 0.022
receptor mediated endocytosis GO:0006898 8 0.022
Human Rat Fly
protein complex disassembly GO:0043241 70 0.021
conjugation with cellular fusion GO:0000747 106 0.021
nucleoside triphosphate catabolic process GO:0009143 329 0.021
regulation of hydrolase activity GO:0051336 133 0.021
translation GO:0006412 230 0.021
dna repair GO:0006281 236 0.020
positive regulation of protein metabolic process GO:0051247 93 0.020
positive regulation of nucleoside metabolic process GO:0045979 97 0.020
regulation of nucleoside metabolic process GO:0009118 106 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.020
negative regulation of nucleic acid templated transcription GO:1903507 260 0.020
negative regulation of dna replication GO:0008156 15 0.019
microtubule polymerization or depolymerization GO:0031109 36 0.019
regulation of cell cycle process GO:0010564 150 0.019
response to osmotic stress GO:0006970 83 0.019
cell development GO:0048468 107 0.019
Fly
response to organic substance GO:0010033 182 0.019
regulation of cellular protein metabolic process GO:0032268 232 0.019
protein targeting to vacuole GO:0006623 91 0.019
monosaccharide transport GO:0015749 24 0.019
nuclear transcribed mrna catabolic process GO:0000956 89 0.019
positive regulation of receptor mediated endocytosis GO:0048260 4 0.019
regulation of mitotic cell cycle phase transition GO:1901990 68 0.019
mrna catabolic process GO:0006402 93 0.018
glycosyl compound catabolic process GO:1901658 335 0.018
monocarboxylic acid metabolic process GO:0032787 122 0.018
histone modification GO:0016570 119 0.018
regulation of establishment of protein localization GO:0070201 17 0.018
negative regulation of signal transduction GO:0009968 30 0.018
negative regulation of protein metabolic process GO:0051248 85 0.018
positive regulation of secretion GO:0051047 2 0.017
dna replication initiation GO:0006270 48 0.017
response to chemical GO:0042221 390 0.017
anatomical structure formation involved in morphogenesis GO:0048646 136 0.017
vesicle organization GO:0016050 68 0.017
regulation of filamentous growth GO:0010570 38 0.017
tor signaling GO:0031929 17 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.017
exocytosis GO:0006887 42 0.017
glucan metabolic process GO:0044042 44 0.017
positive regulation of carbohydrate metabolic process GO:0045913 13 0.017
carboxylic acid metabolic process GO:0019752 338 0.016
protein processing GO:0016485 64 0.016
cell cycle dna replication GO:0044786 36 0.016
late endosome to vacuole transport GO:0045324 42 0.016
cell cycle checkpoint GO:0000075 82 0.016
ribonucleotide catabolic process GO:0009261 327 0.016
regulation of microtubule cytoskeleton organization GO:0070507 32 0.016
purine nucleotide catabolic process GO:0006195 328 0.016
filamentous growth GO:0030447 124 0.016
ribose phosphate metabolic process GO:0019693 384 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.016
regulation of carbohydrate metabolic process GO:0006109 43 0.016
purine nucleoside metabolic process GO:0042278 380 0.016
mrna 3 end processing GO:0031124 54 0.016
negative regulation of cell cycle phase transition GO:1901988 59 0.016
response to organic cyclic compound GO:0014070 1 0.015
cellular bud site selection GO:0000282 35 0.015
negative regulation of cellular catabolic process GO:0031330 43 0.015
developmental process involved in reproduction GO:0003006 159 0.015
positive regulation of apoptotic process GO:0043065 3 0.015
ion homeostasis GO:0050801 118 0.015
protein localization to plasma membrane GO:0072659 18 0.015
protein autophosphorylation GO:0046777 15 0.015
Rat
cell death GO:0008219 30 0.015
plasma membrane organization GO:0007009 21 0.015
cation homeostasis GO:0055080 105 0.015
dna damage checkpoint GO:0000077 29 0.015
ribonucleotide metabolic process GO:0009259 377 0.015
membrane lipid biosynthetic process GO:0046467 54 0.015
regulation of mapk cascade GO:0043408 22 0.015
glycerophospholipid biosynthetic process GO:0046474 68 0.014
organic cyclic compound catabolic process GO:1901361 499 0.014
regulation of cellular response to stress GO:0080135 50 0.014
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 44 0.014
purine nucleoside catabolic process GO:0006152 330 0.014
glucose metabolic process GO:0006006 65 0.014
regulation of phosphorylation GO:0042325 86 0.014
apoptotic process GO:0006915 30 0.014
cell surface receptor signaling pathway GO:0007166 38 0.014
Human
oxidation reduction process GO:0055114 353 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.014
positive regulation of dna templated transcription elongation GO:0032786 42 0.014
establishment of protein localization to organelle GO:0072594 278 0.014
negative regulation of signaling GO:0023057 30 0.013
multi organism cellular process GO:0044764 120 0.013
chromatin silencing at silent mating type cassette GO:0030466 53 0.013
organonitrogen compound biosynthetic process GO:1901566 314 0.013
positive regulation of programmed cell death GO:0043068 3 0.013
negative regulation of gene expression epigenetic GO:0045814 147 0.013
establishment of protein localization to membrane GO:0090150 99 0.013
lipid biosynthetic process GO:0008610 170 0.013
regulation of lipid metabolic process GO:0019216 45 0.013
negative regulation of dna dependent dna replication GO:2000104 8 0.013
iron sulfur cluster assembly GO:0016226 22 0.013
regulation of cellular amine metabolic process GO:0033238 21 0.012
regulation of organelle organization GO:0033043 243 0.012
response to nutrient levels GO:0031667 150 0.012
multi organism reproductive process GO:0044703 216 0.012
purine ribonucleoside metabolic process GO:0046128 380 0.012
response to biotic stimulus GO:0009607 8 0.012
regulation of protein modification process GO:0031399 110 0.012
transition metal ion transport GO:0000041 45 0.012
ribonucleoprotein complex assembly GO:0022618 143 0.012
response to pheromone involved in conjugation with cellular fusion GO:0000749 74 0.012
modification dependent protein catabolic process GO:0019941 181 0.012
cell budding GO:0007114 48 0.012
response to abiotic stimulus GO:0009628 159 0.012
chromatin silencing GO:0006342 147 0.012
rna export from nucleus GO:0006405 88 0.012
regulation of iron sulfur cluster assembly GO:1903329 1 0.012
negative regulation of catabolic process GO:0009895 43 0.012
er to golgi vesicle mediated transport GO:0006888 86 0.012
regulation of catabolic process GO:0009894 199 0.011
regulation of gene expression epigenetic GO:0040029 147 0.011
membrane fusion GO:0061025 73 0.011
response to monosaccharide GO:0034284 13 0.011
regulation of cell cycle phase transition GO:1901987 70 0.011
nucleoside catabolic process GO:0009164 335 0.011
meiosis i GO:0007127 92 0.011
organelle fission GO:0048285 272 0.011
nitrogen utilization GO:0019740 21 0.011
regulation of transmembrane transporter activity GO:0022898 1 0.011
cellular carbohydrate metabolic process GO:0044262 135 0.011
response to oxidative stress GO:0006979 99 0.011
negative regulation of rna biosynthetic process GO:1902679 260 0.011
negative regulation of molecular function GO:0044092 68 0.011
regulation of purine nucleotide metabolic process GO:1900542 109 0.011
cellular component morphogenesis GO:0032989 97 0.011
Fly
negative regulation of cytoskeleton organization GO:0051494 24 0.011
positive regulation of cellular component organization GO:0051130 116 0.011
regulation of gtp catabolic process GO:0033124 84 0.011
nucleotide metabolic process GO:0009117 453 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 29 0.010
ribonucleoside monophosphate catabolic process GO:0009158 224 0.010
negative regulation of mitotic cell cycle GO:0045930 63 0.010
purine nucleoside triphosphate metabolic process GO:0009144 356 0.010
cellular cation homeostasis GO:0030003 100 0.010
cellular amine metabolic process GO:0044106 51 0.010
regulation of dna templated transcription in response to stress GO:0043620 51 0.010
positive regulation of cell cycle GO:0045787 32 0.010
stress activated mapk cascade GO:0051403 4 0.010
protein export from nucleus GO:0006611 17 0.010
cellular protein complex disassembly GO:0043624 42 0.010
stress activated protein kinase signaling cascade GO:0031098 4 0.010

AKL1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
disease of metabolism DOID:0014667 0 0.011