Saccharomyces cerevisiae

39 known processes

AKL1 (YBR059C)

Akl1p

AKL1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytoskeleton organization GO:0007010 230 0.971
vesicle mediated transport GO:0016192 335 0.957
regulation of cell communication GO:0010646 124 0.834
Human
single organism signaling GO:0044700 208 0.786
Human
phosphorylation GO:0016310 291 0.755
regulation of receptor mediated endocytosis GO:0048259 4 0.736
Human Rat Fly
endocytosis GO:0006897 90 0.691
establishment of protein localization GO:0045184 367 0.641
signal transduction GO:0007165 208 0.604
Human
membrane organization GO:0061024 276 0.600
cell communication GO:0007154 345 0.557
Human
secretion by cell GO:0032940 50 0.541
regulation of signaling GO:0023051 119 0.530
Human
regulation of endocytosis GO:0030100 17 0.525
signaling GO:0023052 208 0.521
Human
regulation of response to stimulus GO:0048583 157 0.479
Human
regulation of localization GO:0032879 127 0.467
protein phosphorylation GO:0006468 197 0.453
protein complex biogenesis GO:0070271 314 0.408
regulation of cellular component organization GO:0051128 334 0.400
protein transport GO:0015031 345 0.386
regulation of protein localization GO:0032880 62 0.379
Human
dna replication GO:0006260 147 0.360
regulation of signal transduction GO:0009966 114 0.345
Human
small gtpase mediated signal transduction GO:0007264 36 0.343
organophosphate metabolic process GO:0019637 597 0.336
protein complex assembly GO:0006461 302 0.327
actin filament based process GO:0030029 104 0.259
positive regulation of transport GO:0051050 32 0.242
developmental process GO:0032502 261 0.239
Mouse Fly
positive regulation of signaling GO:0023056 20 0.232
Human
negative regulation of cellular biosynthetic process GO:0031327 312 0.227
regulation of intracellular signal transduction GO:1902531 78 0.223
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.218
membrane lipid metabolic process GO:0006643 67 0.201
anatomical structure development GO:0048856 160 0.199
Mouse Fly
intracellular protein transport GO:0006886 319 0.187
regulation of molecular function GO:0065009 320 0.187
Mouse
single organism membrane organization GO:0044802 275 0.179
autophagy GO:0006914 106 0.170
positive regulation of macromolecule metabolic process GO:0010604 394 0.160
regulation of cell growth GO:0001558 29 0.156
single organism developmental process GO:0044767 258 0.145
Mouse Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.143
positive regulation of phosphorus metabolic process GO:0010562 147 0.143
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.139
actin filament organization GO:0007015 56 0.137
Yeast
positive regulation of endocytosis GO:0045807 12 0.136
positive regulation of cell communication GO:0010647 28 0.136
Human
regulation of transport GO:0051049 85 0.135
actin cytoskeleton organization GO:0030036 100 0.133
guanosine containing compound metabolic process GO:1901068 111 0.131
multi organism process GO:0051704 233 0.129
secretion GO:0046903 50 0.124
cellular protein complex assembly GO:0043623 209 0.123
mitotic cell cycle process GO:1903047 294 0.118
intracellular signal transduction GO:0035556 112 0.116
endomembrane system organization GO:0010256 74 0.114
regulation of dna dependent dna replication GO:0090329 37 0.110
cellular response to pheromone GO:0071444 88 0.110
regulation of phosphorus metabolic process GO:0051174 230 0.109
regulation of dna replication GO:0006275 51 0.106
carbohydrate derivative metabolic process GO:1901135 549 0.104
regulation of proteolysis GO:0030162 44 0.104
glycerolipid biosynthetic process GO:0045017 71 0.103
cell differentiation GO:0030154 161 0.103
Fly
negative regulation of biosynthetic process GO:0009890 312 0.102
positive regulation of response to stimulus GO:0048584 37 0.098
Human
cortical actin cytoskeleton organization GO:0030866 11 0.091
Yeast
positive regulation of signal transduction GO:0009967 20 0.087
Human
carbohydrate metabolic process GO:0005975 252 0.085
membrane budding GO:0006900 22 0.083
reproduction of a single celled organism GO:0032505 191 0.082
mitotic cytokinesis GO:0000281 58 0.082
negative regulation of dna metabolic process GO:0051053 36 0.082
cellular homeostasis GO:0019725 138 0.082
sphingolipid metabolic process GO:0006665 41 0.081
positive regulation of catalytic activity GO:0043085 178 0.081
chromatin silencing at telomere GO:0006348 84 0.081
positive regulation of phosphate metabolic process GO:0045937 147 0.080
peptidyl amino acid modification GO:0018193 116 0.079
establishment of cell polarity GO:0030010 64 0.079
positive regulation of cellular biosynthetic process GO:0031328 336 0.078
nucleocytoplasmic transport GO:0006913 163 0.077
asexual reproduction GO:0019954 48 0.072
proteolysis GO:0006508 268 0.072
mitotic cell cycle GO:0000278 306 0.071
positive regulation of transcription dna templated GO:0045893 286 0.070
anatomical structure morphogenesis GO:0009653 160 0.069
Fly
sexual reproduction GO:0019953 216 0.068
cellular response to organic substance GO:0071310 159 0.067
regulation of small gtpase mediated signal transduction GO:0051056 47 0.067
regulation of phosphate metabolic process GO:0019220 230 0.067
conjugation GO:0000746 107 0.066
cortical cytoskeleton organization GO:0030865 11 0.064
Yeast
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.064
regulation of microtubule based process GO:0032886 32 0.063
cellular developmental process GO:0048869 191 0.063
Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.063
regulation of growth GO:0040008 50 0.063
regulation of biological quality GO:0065008 391 0.062
Human
regulation of catalytic activity GO:0050790 307 0.060
Mouse
negative regulation of cellular metabolic process GO:0031324 407 0.060
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.055
macromolecular complex disassembly GO:0032984 80 0.055
regulation of cell cycle GO:0051726 195 0.053
nuclear division GO:0000280 263 0.053
guanosine containing compound catabolic process GO:1901069 109 0.053
positive regulation of nucleic acid templated transcription GO:1903508 286 0.053
positive regulation of hydrolase activity GO:0051345 112 0.052
purine ribonucleoside catabolic process GO:0046130 330 0.050
positive regulation of biosynthetic process GO:0009891 336 0.049
response to pheromone GO:0019236 92 0.049
nucleoside triphosphate metabolic process GO:0009141 364 0.048
signal transduction by phosphorylation GO:0023014 31 0.047
carbohydrate transport GO:0008643 33 0.047
chemical homeostasis GO:0048878 137 0.047
regulation of protein metabolic process GO:0051246 237 0.047
single organism cellular localization GO:1902580 375 0.047
positive regulation of gtp catabolic process GO:0033126 80 0.047
positive regulation of mapk cascade GO:0043410 10 0.046
nucleobase containing compound catabolic process GO:0034655 479 0.046
cell division GO:0051301 205 0.046
Fly
nucleoside phosphate metabolic process GO:0006753 458 0.045
cell growth GO:0016049 89 0.045
positive regulation of nucleotide catabolic process GO:0030813 97 0.045
regulation of response to stress GO:0080134 57 0.044
positive regulation of phosphorylation GO:0042327 33 0.043
positive regulation of molecular function GO:0044093 185 0.043
purine containing compound catabolic process GO:0072523 332 0.043
regulation of ras protein signal transduction GO:0046578 47 0.043
protein catabolic process GO:0030163 221 0.042
single organism catabolic process GO:0044712 619 0.042
cellular protein catabolic process GO:0044257 213 0.042
negative regulation of transcription dna templated GO:0045892 258 0.042
homeostatic process GO:0042592 227 0.041
regulation of multi organism process GO:0043900 20 0.041
cellular lipid metabolic process GO:0044255 229 0.040
glycerolipid metabolic process GO:0046486 108 0.040
gene silencing GO:0016458 151 0.040
metal ion homeostasis GO:0055065 79 0.039
regulation of cellular localization GO:0060341 50 0.039
cellular response to dna damage stimulus GO:0006974 287 0.039
cellular nitrogen compound catabolic process GO:0044270 494 0.039
sporulation GO:0043934 132 0.039
dna dependent dna replication GO:0006261 115 0.038
organelle localization GO:0051640 128 0.038
purine ribonucleotide metabolic process GO:0009150 372 0.038
receptor metabolic process GO:0043112 8 0.037
negative regulation of cell communication GO:0010648 33 0.036
ras protein signal transduction GO:0007265 29 0.036
cellular response to chemical stimulus GO:0070887 315 0.036
cellular amide metabolic process GO:0043603 59 0.036
protein targeting GO:0006605 272 0.036
positive regulation of ras gtpase activity GO:0032320 41 0.036
mapk cascade GO:0000165 30 0.036
protein localization to membrane GO:0072657 102 0.035
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.035
aromatic compound catabolic process GO:0019439 491 0.035
nucleoside metabolic process GO:0009116 394 0.035
establishment or maintenance of cell polarity GO:0007163 96 0.034
positive regulation of cellular protein metabolic process GO:0032270 89 0.034
phospholipid transport GO:0015914 23 0.034
positive regulation of cell death GO:0010942 3 0.034
positive regulation of purine nucleotide catabolic process GO:0033123 97 0.033
positive regulation of purine nucleotide metabolic process GO:1900544 100 0.033
gtp catabolic process GO:0006184 107 0.033
cellular macromolecule catabolic process GO:0044265 363 0.032
reproductive process GO:0022414 248 0.032
regulation of chromatin silencing at telomere GO:0031938 27 0.032
cellular component disassembly GO:0022411 86 0.032
negative regulation of microtubule polymerization or depolymerization GO:0031111 7 0.031
actin cortical patch organization GO:0044396 10 0.031
Yeast
cation transport GO:0006812 166 0.031
positive regulation of cytoplasmic transport GO:1903651 4 0.031
ribonucleoside catabolic process GO:0042454 332 0.030
regulation of purine nucleotide catabolic process GO:0033121 106 0.030
carbohydrate derivative catabolic process GO:1901136 339 0.030
protein localization to vacuole GO:0072665 92 0.030
endosomal transport GO:0016197 86 0.030
death GO:0016265 30 0.029
sporulation resulting in formation of a cellular spore GO:0030435 129 0.029
positive regulation of gtpase activity GO:0043547 80 0.029
regulation of mitotic cell cycle GO:0007346 107 0.029
protein maturation GO:0051604 76 0.029
regulation of gtpase activity GO:0043087 84 0.029
protein localization to organelle GO:0033365 337 0.029
positive regulation of rna metabolic process GO:0051254 294 0.029
negative regulation of rna metabolic process GO:0051253 262 0.028
late endosome to vacuole transport via multivesicular body sorting pathway GO:0032511 26 0.028
meiotic cell cycle process GO:1903046 229 0.028
nucleoside phosphate catabolic process GO:1901292 331 0.028
regulation of nucleotide catabolic process GO:0030811 106 0.028
positive regulation of nucleotide metabolic process GO:0045981 101 0.028
regulation of pseudohyphal growth GO:2000220 18 0.028
reproductive process in single celled organism GO:0022413 145 0.028
regulation of microtubule polymerization GO:0031113 14 0.027
actin cortical patch assembly GO:0000147 9 0.027
Yeast
regulation of vesicle mediated transport GO:0060627 39 0.027
establishment of organelle localization GO:0051656 96 0.027
microtubule cytoskeleton organization GO:0000226 109 0.027
sphingolipid biosynthetic process GO:0030148 29 0.027
regulation of cell size GO:0008361 30 0.027
positive regulation of secretion by cell GO:1903532 2 0.026
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.026
negative regulation of macromolecule metabolic process GO:0010605 375 0.026
energy derivation by oxidation of organic compounds GO:0015980 125 0.026
positive regulation of intracellular protein transport GO:0090316 3 0.026
glycerophospholipid metabolic process GO:0006650 98 0.026
growth GO:0040007 157 0.025
phospholipid metabolic process GO:0006644 125 0.025
fungal type cell wall organization GO:0031505 145 0.025
ion transport GO:0006811 274 0.025
nucleotide catabolic process GO:0009166 330 0.025
heterocycle catabolic process GO:0046700 494 0.025
lipid metabolic process GO:0006629 269 0.025
regulation of nucleotide metabolic process GO:0006140 110 0.025
macromolecule catabolic process GO:0009057 383 0.024
negative regulation of cellular component organization GO:0051129 109 0.024
positive regulation of nucleocytoplasmic transport GO:0046824 4 0.024
single organism membrane fusion GO:0044801 71 0.024
response to external stimulus GO:0009605 158 0.023
negative regulation of phosphorylation GO:0042326 28 0.023
microtubule polymerization GO:0046785 30 0.023
amine metabolic process GO:0009308 51 0.023
regulation of ras gtpase activity GO:0032318 41 0.023
regulation of dna metabolic process GO:0051052 100 0.023
nucleobase containing small molecule metabolic process GO:0055086 491 0.023
covalent chromatin modification GO:0016569 119 0.022
positive regulation of intracellular transport GO:0032388 4 0.022
purine ribonucleotide catabolic process GO:0009154 327 0.022
receptor mediated endocytosis GO:0006898 8 0.022
Human Rat Fly
protein complex disassembly GO:0043241 70 0.021
conjugation with cellular fusion GO:0000747 106 0.021
nucleoside triphosphate catabolic process GO:0009143 329 0.021
regulation of hydrolase activity GO:0051336 133 0.021
translation GO:0006412 230 0.021
dna repair GO:0006281 236 0.020
positive regulation of protein metabolic process GO:0051247 93 0.020
positive regulation of nucleoside metabolic process GO:0045979 97 0.020
regulation of nucleoside metabolic process GO:0009118 106 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.020
negative regulation of nucleic acid templated transcription GO:1903507 260 0.020
negative regulation of dna replication GO:0008156 15 0.019
microtubule polymerization or depolymerization GO:0031109 36 0.019
regulation of cell cycle process GO:0010564 150 0.019
response to osmotic stress GO:0006970 83 0.019
cell development GO:0048468 107 0.019
Fly
response to organic substance GO:0010033 182 0.019
regulation of cellular protein metabolic process GO:0032268 232 0.019
protein targeting to vacuole GO:0006623 91 0.019
monosaccharide transport GO:0015749 24 0.019
nuclear transcribed mrna catabolic process GO:0000956 89 0.019
positive regulation of receptor mediated endocytosis GO:0048260 4 0.019
regulation of mitotic cell cycle phase transition GO:1901990 68 0.019
mrna catabolic process GO:0006402 93 0.018
glycosyl compound catabolic process GO:1901658 335 0.018
monocarboxylic acid metabolic process GO:0032787 122 0.018
histone modification GO:0016570 119 0.018
regulation of establishment of protein localization GO:0070201 17 0.018
negative regulation of signal transduction GO:0009968 30 0.018
negative regulation of protein metabolic process GO:0051248 85 0.018
positive regulation of secretion GO:0051047 2 0.017
dna replication initiation GO:0006270 48 0.017
response to chemical GO:0042221 390 0.017
anatomical structure formation involved in morphogenesis GO:0048646 136 0.017
vesicle organization GO:0016050 68 0.017
regulation of filamentous growth GO:0010570 38 0.017
tor signaling GO:0031929 17 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.017
exocytosis GO:0006887 42 0.017
glucan metabolic process GO:0044042 44 0.017
positive regulation of carbohydrate metabolic process GO:0045913 13 0.017
carboxylic acid metabolic process GO:0019752 338 0.016
protein processing GO:0016485 64 0.016
cell cycle dna replication GO:0044786 36 0.016
late endosome to vacuole transport GO:0045324 42 0.016
cell cycle checkpoint GO:0000075 82 0.016
ribonucleotide catabolic process GO:0009261 327 0.016
regulation of microtubule cytoskeleton organization GO:0070507 32 0.016
purine nucleotide catabolic process GO:0006195 328 0.016
filamentous growth GO:0030447 124 0.016
ribose phosphate metabolic process GO:0019693 384 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.016
regulation of carbohydrate metabolic process GO:0006109 43 0.016
purine nucleoside metabolic process GO:0042278 380 0.016
mrna 3 end processing GO:0031124 54 0.016
negative regulation of cell cycle phase transition GO:1901988 59 0.016
response to organic cyclic compound GO:0014070 1 0.015
cellular bud site selection GO:0000282 35 0.015
negative regulation of cellular catabolic process GO:0031330 43 0.015
developmental process involved in reproduction GO:0003006 159 0.015
positive regulation of apoptotic process GO:0043065 3 0.015
ion homeostasis GO:0050801 118 0.015
protein localization to plasma membrane GO:0072659 18 0.015
protein autophosphorylation GO:0046777 15 0.015
Rat
cell death GO:0008219 30 0.015
plasma membrane organization GO:0007009 21 0.015
cation homeostasis GO:0055080 105 0.015
dna damage checkpoint GO:0000077 29 0.015
ribonucleotide metabolic process GO:0009259 377 0.015
membrane lipid biosynthetic process GO:0046467 54 0.015
regulation of mapk cascade GO:0043408 22 0.015
glycerophospholipid biosynthetic process GO:0046474 68 0.014
organic cyclic compound catabolic process GO:1901361 499 0.014
regulation of cellular response to stress GO:0080135 50 0.014
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 44 0.014
purine nucleoside catabolic process GO:0006152 330 0.014
glucose metabolic process GO:0006006 65 0.014
regulation of phosphorylation GO:0042325 86 0.014
apoptotic process GO:0006915 30 0.014
cell surface receptor signaling pathway GO:0007166 38 0.014
Human
oxidation reduction process GO:0055114 353 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.014
positive regulation of dna templated transcription elongation GO:0032786 42 0.014
establishment of protein localization to organelle GO:0072594 278 0.014
negative regulation of signaling GO:0023057 30 0.013
multi organism cellular process GO:0044764 120 0.013
chromatin silencing at silent mating type cassette GO:0030466 53 0.013
organonitrogen compound biosynthetic process GO:1901566 314 0.013
positive regulation of programmed cell death GO:0043068 3 0.013
negative regulation of gene expression epigenetic GO:0045814 147 0.013
establishment of protein localization to membrane GO:0090150 99 0.013
lipid biosynthetic process GO:0008610 170 0.013
regulation of lipid metabolic process GO:0019216 45 0.013
negative regulation of dna dependent dna replication GO:2000104 8 0.013
iron sulfur cluster assembly GO:0016226 22 0.013
regulation of cellular amine metabolic process GO:0033238 21 0.012
regulation of organelle organization GO:0033043 243 0.012
response to nutrient levels GO:0031667 150 0.012
multi organism reproductive process GO:0044703 216 0.012
purine ribonucleoside metabolic process GO:0046128 380 0.012
response to biotic stimulus GO:0009607 8 0.012
regulation of protein modification process GO:0031399 110 0.012
transition metal ion transport GO:0000041 45 0.012
ribonucleoprotein complex assembly GO:0022618 143 0.012
response to pheromone involved in conjugation with cellular fusion GO:0000749 74 0.012
modification dependent protein catabolic process GO:0019941 181 0.012
cell budding GO:0007114 48 0.012
response to abiotic stimulus GO:0009628 159 0.012
chromatin silencing GO:0006342 147 0.012
rna export from nucleus GO:0006405 88 0.012
regulation of iron sulfur cluster assembly GO:1903329 1 0.012
negative regulation of catabolic process GO:0009895 43 0.012
er to golgi vesicle mediated transport GO:0006888 86 0.012
regulation of catabolic process GO:0009894 199 0.011
regulation of gene expression epigenetic GO:0040029 147 0.011
membrane fusion GO:0061025 73 0.011
response to monosaccharide GO:0034284 13 0.011
regulation of cell cycle phase transition GO:1901987 70 0.011
nucleoside catabolic process GO:0009164 335 0.011
meiosis i GO:0007127 92 0.011
organelle fission GO:0048285 272 0.011
nitrogen utilization GO:0019740 21 0.011
regulation of transmembrane transporter activity GO:0022898 1 0.011
cellular carbohydrate metabolic process GO:0044262 135 0.011
response to oxidative stress GO:0006979 99 0.011
negative regulation of rna biosynthetic process GO:1902679 260 0.011
negative regulation of molecular function GO:0044092 68 0.011
regulation of purine nucleotide metabolic process GO:1900542 109 0.011
cellular component morphogenesis GO:0032989 97 0.011
Fly
negative regulation of cytoskeleton organization GO:0051494 24 0.011
positive regulation of cellular component organization GO:0051130 116 0.011
regulation of gtp catabolic process GO:0033124 84 0.011
nucleotide metabolic process GO:0009117 453 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 29 0.010
ribonucleoside monophosphate catabolic process GO:0009158 224 0.010
negative regulation of mitotic cell cycle GO:0045930 63 0.010
purine nucleoside triphosphate metabolic process GO:0009144 356 0.010
cellular cation homeostasis GO:0030003 100 0.010
cellular amine metabolic process GO:0044106 51 0.010
regulation of dna templated transcription in response to stress GO:0043620 51 0.010
positive regulation of cell cycle GO:0045787 32 0.010
stress activated mapk cascade GO:0051403 4 0.010
protein export from nucleus GO:0006611 17 0.010
cellular protein complex disassembly GO:0043624 42 0.010
stress activated protein kinase signaling cascade GO:0031098 4 0.010

AKL1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.016
cancer DOID:162 0 0.016
organ system cancer DOID:0050686 0 0.016
disease of metabolism DOID:0014667 0 0.011