Saccharomyces cerevisiae

130 known processes

VPS4 (YPR173C)

Vps4p

(Aliases: VPT10,GRD13,CSC1,DID6,END13,VPL4)

VPS4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vacuolar transport GO:0007034 145 0.996
single organism cellular localization GO:1902580 375 0.978
protein transport GO:0015031 345 0.967
establishment of protein localization GO:0045184 367 0.962
late endosome to vacuole transport via multivesicular body sorting pathway GO:0032511 26 0.929
late endosome to vacuole transport GO:0045324 42 0.920
protein targeting GO:0006605 272 0.890
establishment of protein localization to vacuole GO:0072666 91 0.808
endosome transport via multivesicular body sorting pathway GO:0032509 27 0.751
protein localization to organelle GO:0033365 337 0.656
nucleoside phosphate metabolic process GO:0006753 458 0.647
intracellular protein transport GO:0006886 319 0.642
aromatic compound catabolic process GO:0019439 491 0.636
protein localization to vacuole GO:0072665 92 0.614
establishment of protein localization to organelle GO:0072594 278 0.523
nucleoside phosphate catabolic process GO:1901292 331 0.429
cellular nitrogen compound catabolic process GO:0044270 494 0.427
vesicle mediated transport GO:0016192 335 0.422
endosomal transport GO:0016197 86 0.394
nucleotide metabolic process GO:0009117 453 0.330
membrane organization GO:0061024 276 0.322
nucleoside catabolic process GO:0009164 335 0.320
regulation of cellular component organization GO:0051128 334 0.298
purine ribonucleotide metabolic process GO:0009150 372 0.295
nucleoside triphosphate metabolic process GO:0009141 364 0.285
protein targeting to vacuole GO:0006623 91 0.276
single organism membrane organization GO:0044802 275 0.268
ribonucleoside triphosphate catabolic process GO:0009203 327 0.247
purine nucleotide metabolic process GO:0006163 376 0.247
organic cyclic compound catabolic process GO:1901361 499 0.246
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.244
response to organic substance GO:0010033 182 0.231
Human
ribonucleoside catabolic process GO:0042454 332 0.225
nucleobase containing compound catabolic process GO:0034655 479 0.220
regulation of vesicle mediated transport GO:0060627 39 0.219
Human
regulation of response to stimulus GO:0048583 157 0.202
Fly
ribonucleotide catabolic process GO:0009261 327 0.197
purine nucleoside triphosphate catabolic process GO:0009146 329 0.195
organonitrogen compound catabolic process GO:1901565 404 0.194
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.192
nucleotide catabolic process GO:0009166 330 0.178
cell communication GO:0007154 345 0.175
Fly
cellular macromolecule catabolic process GO:0044265 363 0.171
Human Fly
ribose phosphate metabolic process GO:0019693 384 0.166
purine nucleotide catabolic process GO:0006195 328 0.164
multi organism process GO:0051704 233 0.156
Human Fly
ribonucleoside triphosphate metabolic process GO:0009199 356 0.153
purine ribonucleoside catabolic process GO:0046130 330 0.150
nucleobase containing small molecule metabolic process GO:0055086 491 0.142
ribonucleotide metabolic process GO:0009259 377 0.142
multi organism reproductive process GO:0044703 216 0.141
purine containing compound catabolic process GO:0072523 332 0.140
signal transduction GO:0007165 208 0.138
Fly
ribonucleoside monophosphate metabolic process GO:0009161 265 0.137
protein complex biogenesis GO:0070271 314 0.135
macromolecule catabolic process GO:0009057 383 0.135
Human Fly
nucleoside metabolic process GO:0009116 394 0.133
purine nucleoside catabolic process GO:0006152 330 0.133
ribonucleoside metabolic process GO:0009119 389 0.129
endocytosis GO:0006897 90 0.120
Fly
purine nucleoside metabolic process GO:0042278 380 0.118
ubiquitin dependent protein catabolic process GO:0006511 181 0.117
Human Fly
signaling GO:0023052 208 0.117
Fly
heterocycle catabolic process GO:0046700 494 0.116
organelle localization GO:0051640 128 0.115
regulation of signal transduction GO:0009966 114 0.113
Fly
purine nucleoside monophosphate metabolic process GO:0009126 262 0.113
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.112
organophosphate catabolic process GO:0046434 338 0.112
negative regulation of signal transduction GO:0009968 30 0.111
Fly
positive regulation of catalytic activity GO:0043085 178 0.110
purine ribonucleoside metabolic process GO:0046128 380 0.109
regulation of signaling GO:0023051 119 0.108
Fly
carbohydrate derivative catabolic process GO:1901136 339 0.108
carbohydrate derivative metabolic process GO:1901135 549 0.105
purine nucleoside triphosphate metabolic process GO:0009144 356 0.104
sexual reproduction GO:0019953 216 0.103
membrane budding GO:0006900 22 0.101
modification dependent macromolecule catabolic process GO:0043632 203 0.098
Human Fly
single organism catabolic process GO:0044712 619 0.094
mitotic cell cycle process GO:1903047 294 0.092
Human
atp metabolic process GO:0046034 251 0.091
regulation of multi organism process GO:0043900 20 0.091
Human Fly
response to chemical GO:0042221 390 0.086
Human
purine ribonucleotide catabolic process GO:0009154 327 0.082
negative regulation of signaling GO:0023057 30 0.082
Fly
positive regulation of phosphorus metabolic process GO:0010562 147 0.081
cell surface receptor signaling pathway GO:0007166 38 0.079
Fly
vesicle organization GO:0016050 68 0.079
negative regulation of cellular biosynthetic process GO:0031327 312 0.078
nitrogen compound transport GO:0071705 212 0.076
rna catabolic process GO:0006401 118 0.073
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.072
chromatin modification GO:0016568 200 0.072
protein complex assembly GO:0006461 302 0.072
protein localization to membrane GO:0072657 102 0.071
establishment of protein localization to membrane GO:0090150 99 0.068
regulation of purine nucleotide metabolic process GO:1900542 109 0.066
single organism signaling GO:0044700 208 0.066
Fly
positive regulation of cellular component organization GO:0051130 116 0.065
localization within membrane GO:0051668 29 0.063
cellular response to organic substance GO:0071310 159 0.063
regulation of nucleoside metabolic process GO:0009118 106 0.063
multi organism cellular process GO:0044764 120 0.062
Human
positive regulation of nucleotide metabolic process GO:0045981 101 0.062
modification dependent protein catabolic process GO:0019941 181 0.061
Human Fly
nucleoside monophosphate metabolic process GO:0009123 267 0.061
dna recombination GO:0006310 172 0.061
regulation of biological quality GO:0065008 391 0.061
histone modification GO:0016570 119 0.060
regulation of catabolic process GO:0009894 199 0.059
positive regulation of purine nucleotide metabolic process GO:1900544 100 0.059
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.056
regulation of cellular catabolic process GO:0031329 195 0.055
negative regulation of nucleic acid templated transcription GO:1903507 260 0.053
negative regulation of response to stimulus GO:0048585 40 0.053
Fly
organophosphate metabolic process GO:0019637 597 0.051
double strand break repair GO:0006302 105 0.050
positive regulation of cellular catabolic process GO:0031331 128 0.048
response to temperature stimulus GO:0009266 74 0.048
positive regulation of nucleotide catabolic process GO:0030813 97 0.047
negative regulation of rna biosynthetic process GO:1902679 260 0.047
positive regulation of catabolic process GO:0009896 135 0.046
mitotic cell cycle GO:0000278 306 0.044
Human
glycosyl compound catabolic process GO:1901658 335 0.044
regulation of phosphate metabolic process GO:0019220 230 0.043
negative regulation of transcription dna templated GO:0045892 258 0.043
growth GO:0040007 157 0.043
Fly
glycerolipid metabolic process GO:0046486 108 0.041
response to abiotic stimulus GO:0009628 159 0.041
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.040
ribonucleoside monophosphate catabolic process GO:0009158 224 0.040
negative regulation of cellular metabolic process GO:0031324 407 0.039
regulation of cellular component biogenesis GO:0044087 112 0.038
chromatin organization GO:0006325 242 0.038
golgi vesicle transport GO:0048193 188 0.037
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.037
ncrna processing GO:0034470 330 0.035
cellular response to dna damage stimulus GO:0006974 287 0.035
negative regulation of biosynthetic process GO:0009890 312 0.034
glycosyl compound metabolic process GO:1901657 398 0.034
peptidyl lysine modification GO:0018205 77 0.034
homeostatic process GO:0042592 227 0.033
mrna metabolic process GO:0016071 269 0.033
maintenance of location GO:0051235 66 0.032
nucleoside triphosphate catabolic process GO:0009143 329 0.031
cellular ketone metabolic process GO:0042180 63 0.031
regulation of molecular function GO:0065009 320 0.031
ribosomal small subunit biogenesis GO:0042274 124 0.031
regulation of nucleotide metabolic process GO:0006140 110 0.030
cellular response to chemical stimulus GO:0070887 315 0.030
negative regulation of rna metabolic process GO:0051253 262 0.029
regulation of nucleotide catabolic process GO:0030811 106 0.029
methylation GO:0032259 101 0.029
positive regulation of protein metabolic process GO:0051247 93 0.028
negative regulation of cell communication GO:0010648 33 0.028
Fly
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 44 0.028
cell wall organization or biogenesis GO:0071554 190 0.028
cellular chemical homeostasis GO:0055082 123 0.027
positive regulation of hydrolase activity GO:0051345 112 0.027
covalent chromatin modification GO:0016569 119 0.027
regulation of cell communication GO:0010646 124 0.026
Fly
positive regulation of protein complex assembly GO:0031334 39 0.026
atp catabolic process GO:0006200 224 0.026
reproductive process GO:0022414 248 0.025
chromatin silencing GO:0006342 147 0.025
regulation of transport GO:0051049 85 0.025
Human
positive regulation of molecular function GO:0044093 185 0.025
protein modification by small protein conjugation or removal GO:0070647 172 0.024
positive regulation of macromolecule metabolic process GO:0010604 394 0.024
organelle fission GO:0048285 272 0.024
single organism membrane fusion GO:0044801 71 0.024
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.023
Human Fly
conjugation GO:0000746 107 0.023
protein catabolic process GO:0030163 221 0.022
Human Fly
posttranscriptional regulation of gene expression GO:0010608 115 0.022
invasive filamentous growth GO:0036267 65 0.022
fungal type cell wall organization or biogenesis GO:0071852 169 0.022
establishment of organelle localization GO:0051656 96 0.022
chemical homeostasis GO:0048878 137 0.022
conjugation with cellular fusion GO:0000747 106 0.021
response to nutrient GO:0007584 52 0.021
positive regulation of phosphate metabolic process GO:0045937 147 0.020
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.020
anatomical structure development GO:0048856 160 0.020
peptidyl amino acid modification GO:0018193 116 0.019
response to pheromone involved in conjugation with cellular fusion GO:0000749 74 0.019
developmental process GO:0032502 261 0.018
Human
negative regulation of multi organism process GO:0043901 6 0.018
Fly
aging GO:0007568 71 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.018
negative regulation of gene expression GO:0010629 312 0.018
gtp catabolic process GO:0006184 107 0.018
cellular homeostasis GO:0019725 138 0.018
ribosomal large subunit biogenesis GO:0042273 98 0.018
autophagy GO:0006914 106 0.018
Fly
positive regulation of cellular protein metabolic process GO:0032270 89 0.018
nuclear transcribed mrna catabolic process GO:0000956 89 0.017
anatomical structure morphogenesis GO:0009653 160 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.017
regulation of localization GO:0032879 127 0.017
Human
response to oxygen containing compound GO:1901700 61 0.017
chromatin remodeling GO:0006338 80 0.016
monovalent inorganic cation homeostasis GO:0055067 32 0.016
positive regulation of secretion GO:0051047 2 0.016
Human
regulation of intracellular transport GO:0032386 26 0.016
cellular response to pheromone GO:0071444 88 0.016
dna repair GO:0006281 236 0.016
meiotic cell cycle GO:0051321 272 0.015
lipid metabolic process GO:0006629 269 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.015
positive regulation of transport GO:0051050 32 0.015
Human
establishment of vesicle localization GO:0051650 9 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.015
nuclear import GO:0051170 57 0.015
cellular protein catabolic process GO:0044257 213 0.014
Human Fly
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.014
response to extracellular stimulus GO:0009991 156 0.014
Fly
regulation of cellular localization GO:0060341 50 0.014
Human
positive regulation of gene expression GO:0010628 321 0.014
ion transport GO:0006811 274 0.014
Mouse
organelle assembly GO:0070925 118 0.014
cellular protein complex assembly GO:0043623 209 0.013
regulation of cellular ketone metabolic process GO:0010565 42 0.013
single organism reproductive process GO:0044702 159 0.013
positive regulation of intracellular transport GO:0032388 4 0.013
single organism membrane budding GO:1902591 21 0.013
negative regulation of macromolecule metabolic process GO:0010605 375 0.013
organelle fusion GO:0048284 85 0.013
Fly
invasive growth in response to glucose limitation GO:0001403 61 0.013
positive regulation of biosynthetic process GO:0009891 336 0.013
nucleocytoplasmic transport GO:0006913 163 0.013
carbohydrate metabolic process GO:0005975 252 0.012
phospholipid metabolic process GO:0006644 125 0.012
filamentous growth of a population of unicellular organisms GO:0044182 109 0.012
alcohol biosynthetic process GO:0046165 75 0.012
single organism developmental process GO:0044767 258 0.012
Human
proteolysis GO:0006508 268 0.012
Human Fly
post golgi vesicle mediated transport GO:0006892 72 0.012
cytoskeleton organization GO:0007010 230 0.012
Fly
rna localization GO:0006403 112 0.012
organelle inheritance GO:0048308 51 0.012
mrna catabolic process GO:0006402 93 0.012
cellular component movement GO:0006928 20 0.012
sporulation GO:0043934 132 0.011
regulation of gene silencing GO:0060968 41 0.011
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 12 0.011
Human Fly
guanosine containing compound metabolic process GO:1901068 111 0.011
positive regulation of secretion by cell GO:1903532 2 0.011
Human
response to heat GO:0009408 69 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 97 0.011
organic hydroxy compound metabolic process GO:1901615 125 0.011
purine containing compound metabolic process GO:0072521 400 0.011
meiotic cell cycle process GO:1903046 229 0.011
positive regulation of organelle organization GO:0010638 85 0.011
purine nucleoside monophosphate catabolic process GO:0009128 224 0.011
protein methylation GO:0006479 48 0.011
regulation of cytoplasmic transport GO:1903649 24 0.011
negative regulation of intracellular signal transduction GO:1902532 27 0.010
internal peptidyl lysine acetylation GO:0018393 52 0.010
regulation of organelle organization GO:0033043 243 0.010
carboxylic acid metabolic process GO:0019752 338 0.010
filamentous growth GO:0030447 124 0.010
negative regulation of organelle organization GO:0010639 103 0.010
negative regulation of gene expression epigenetic GO:0045814 147 0.010

VPS4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org