|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
394 |
0.696
|
|
|
phosphorylation
|
GO:0016310 |
291 |
0.535
|
|
|
mitotic cell cycle process
|
GO:1903047 |
294 |
0.525
|
|
|
chromosome segregation
|
GO:0007059 |
159 |
0.488
|
|
|
meiotic cell cycle process
|
GO:1903046 |
229 |
0.439
|
|
|
mitotic cell cycle
|
GO:0000278 |
306 |
0.427
|
|
|
single organism membrane organization
|
GO:0044802 |
275 |
0.399
|
|
|
membrane organization
|
GO:0061024 |
276 |
0.315
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
491 |
0.290
|
|
|
regulation of cellular component organization
|
GO:0051128 |
334 |
0.282
|
|
|
regulation of biological quality
|
GO:0065008 |
391 |
0.281
|
|
|
regulation of cell communication
|
GO:0010646 |
124 |
0.211
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
86 |
0.194
|
|
|
protein phosphorylation
|
GO:0006468 |
197 |
0.190
|
|
|
dna replication
|
GO:0006260 |
147 |
0.189
|
|
|
sister chromatid segregation
|
GO:0000819 |
93 |
0.169
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
412 |
0.167
|
|
|
cell communication
|
GO:0007154 |
345 |
0.160
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
494 |
0.158
|
|
|
regulation of molecular function
|
GO:0065009 |
320 |
0.156
|
|
|
proteolysis
|
GO:0006508 |
268 |
0.145
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
198 |
0.144
|
|
|
dna replication initiation
|
GO:0006270 |
48 |
0.134
|
|
|
heterocycle catabolic process
|
GO:0046700 |
494 |
0.126
|
|
|
negative regulation of mitosis
|
GO:0045839 |
39 |
0.124
|
|
|
dna dependent dna replication
|
GO:0006261 |
115 |
0.123
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
287 |
0.122
|
|
|
regulation of organelle organization
|
GO:0033043 |
243 |
0.117
|
|
|
microtubule based process
|
GO:0007017 |
117 |
0.115
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
325 |
0.114
|
Human |
|
proteasomal protein catabolic process
|
GO:0010498 |
141 |
0.106
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
336 |
0.102
|
Human |
|
organophosphate metabolic process
|
GO:0019637 |
597 |
0.096
|
|
|
mitotic nuclear division
|
GO:0007067 |
131 |
0.095
|
|
|
cell cycle checkpoint
|
GO:0000075 |
82 |
0.089
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
203 |
0.085
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
479 |
0.084
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
103 |
0.084
|
|
|
spindle organization
|
GO:0007051 |
37 |
0.082
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
109 |
0.077
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
107 |
0.077
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
237 |
0.076
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
363 |
0.074
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
499 |
0.074
|
|
|
meiotic cell cycle
|
GO:0051321 |
272 |
0.074
|
|
|
cellular protein catabolic process
|
GO:0044257 |
213 |
0.073
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
336 |
0.072
|
Human |
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
89 |
0.072
|
|
|
nuclear division
|
GO:0000280 |
263 |
0.070
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
407 |
0.070
|
|
|
cell cycle phase transition
|
GO:0044770 |
144 |
0.068
|
Human |
|
organelle fission
|
GO:0048285 |
272 |
0.066
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
338 |
0.066
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
409 |
0.065
|
|
|
mitotic spindle organization
|
GO:0007052 |
30 |
0.064
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
230 |
0.063
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
147 |
0.063
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
109 |
0.062
|
|
|
regulation of dna dependent dna replication
|
GO:0090329 |
37 |
0.061
|
Human |
|
regulation of signaling
|
GO:0023051 |
119 |
0.061
|
|
|
regulation of mitosis
|
GO:0007088 |
65 |
0.060
|
|
|
signal transduction
|
GO:0007165 |
208 |
0.060
|
|
|
homeostatic process
|
GO:0042592 |
227 |
0.060
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
404 |
0.058
|
|
|
meiotic nuclear division
|
GO:0007126 |
163 |
0.057
|
|
|
oxoacid metabolic process
|
GO:0043436 |
351 |
0.054
|
|
|
response to chemical
|
GO:0042221 |
390 |
0.054
|
|
|
dna conformation change
|
GO:0071103 |
98 |
0.052
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
85 |
0.052
|
|
|
regulation of protein modification process
|
GO:0031399 |
110 |
0.052
|
|
|
ion homeostasis
|
GO:0050801 |
118 |
0.051
|
|
|
regulation of cell cycle
|
GO:0051726 |
195 |
0.050
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
172 |
0.049
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
123 |
0.047
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
232 |
0.046
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
491 |
0.046
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
181 |
0.045
|
|
|
protein complex assembly
|
GO:0006461 |
302 |
0.044
|
|
|
regulation of catalytic activity
|
GO:0050790 |
307 |
0.044
|
|
|
double strand break repair
|
GO:0006302 |
105 |
0.044
|
|
|
signaling
|
GO:0023052 |
208 |
0.044
|
|
|
cellular homeostasis
|
GO:0019725 |
138 |
0.043
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
39 |
0.043
|
|
|
regulation of signal transduction
|
GO:0009966 |
114 |
0.042
|
|
|
organic anion transport
|
GO:0015711 |
114 |
0.042
|
|
|
cell division
|
GO:0051301 |
205 |
0.041
|
|
|
single organism catabolic process
|
GO:0044712 |
619 |
0.041
|
|
|
organelle assembly
|
GO:0070925 |
118 |
0.041
|
|
|
positive regulation of molecular function
|
GO:0044093 |
185 |
0.041
|
|
|
negative regulation of nuclear division
|
GO:0051784 |
62 |
0.041
|
|
|
nucleoside metabolic process
|
GO:0009116 |
394 |
0.041
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
31 |
0.041
|
|
|
regulation of dna replication
|
GO:0006275 |
51 |
0.040
|
Human |
|
negative regulation of catabolic process
|
GO:0009895 |
43 |
0.040
|
|
|
regulation of cell division
|
GO:0051302 |
113 |
0.040
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
67 |
0.040
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
141 |
0.040
|
Human |
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
312 |
0.040
|
|
|
macromolecule catabolic process
|
GO:0009057 |
383 |
0.039
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
36 |
0.039
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
229 |
0.039
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
230 |
0.039
|
|
|
cellular ion homeostasis
|
GO:0006873 |
112 |
0.038
|
|
|
regulation of transferase activity
|
GO:0051338 |
83 |
0.037
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
327 |
0.037
|
|
|
protein processing
|
GO:0016485 |
64 |
0.037
|
|
|
single organism cellular localization
|
GO:1902580 |
375 |
0.036
|
|
|
regulation of response to stimulus
|
GO:0048583 |
157 |
0.036
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
85 |
0.036
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
63 |
0.036
|
|
|
regulation of dna dependent dna replication initiation
|
GO:0030174 |
21 |
0.036
|
|
|
nucleotide metabolic process
|
GO:0009117 |
453 |
0.035
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
49 |
0.035
|
|
|
cytoskeleton organization
|
GO:0007010 |
230 |
0.034
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
34 |
0.033
|
|
|
protein ubiquitination
|
GO:0016567 |
118 |
0.033
|
|
|
nucleobase containing compound transport
|
GO:0015931 |
124 |
0.032
|
|
|
chemical homeostasis
|
GO:0048878 |
137 |
0.032
|
|
|
regulation of protein phosphorylation
|
GO:0001932 |
75 |
0.031
|
|
|
regulation of nuclear division
|
GO:0051783 |
103 |
0.030
|
|
|
cell cycle dna replication
|
GO:0044786 |
36 |
0.029
|
|
|
nitrogen compound transport
|
GO:0071705 |
212 |
0.029
|
|
|
ion transport
|
GO:0006811 |
274 |
0.029
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
78 |
0.029
|
|
|
protein maturation
|
GO:0051604 |
76 |
0.029
|
|
|
cellular response to chemical stimulus
|
GO:0070887 |
315 |
0.029
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
100 |
0.029
|
Human |
|
positive regulation of transcription dna templated
|
GO:0045893 |
286 |
0.029
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
85 |
0.028
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
295 |
0.028
|
|
|
response to starvation
|
GO:0042594 |
96 |
0.027
|
|
|
positive regulation of gene expression
|
GO:0010628 |
321 |
0.027
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
147 |
0.027
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
181 |
0.027
|
|
|
endomembrane system organization
|
GO:0010256 |
74 |
0.027
|
|
|
regulation of phosphorylation
|
GO:0042325 |
86 |
0.026
|
|
|
organic acid metabolic process
|
GO:0006082 |
352 |
0.026
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
329 |
0.026
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
375 |
0.025
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
56 |
0.025
|
|
|
regulation of catabolic process
|
GO:0009894 |
199 |
0.025
|
|
|
regulation of kinase activity
|
GO:0043549 |
71 |
0.025
|
|
|
cation homeostasis
|
GO:0055080 |
105 |
0.024
|
|
|
mitotic spindle checkpoint
|
GO:0071174 |
34 |
0.024
|
|
|
regulation of chromosome organization
|
GO:0033044 |
66 |
0.024
|
|
|
cellular cation homeostasis
|
GO:0030003 |
100 |
0.024
|
|
|
response to organic cyclic compound
|
GO:0014070 |
1 |
0.024
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
80 |
0.024
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
36 |
0.024
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
70 |
0.023
|
Human |
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
356 |
0.023
|
|
|
meiosis i
|
GO:0007127 |
92 |
0.023
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
64 |
0.023
|
|
|
spindle checkpoint
|
GO:0031577 |
35 |
0.022
|
|
|
negative regulation of mitotic sister chromatid segregation
|
GO:0033048 |
24 |
0.022
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
39 |
0.022
|
Human |
|
protein dephosphorylation
|
GO:0006470 |
40 |
0.022
|
|
|
vesicle mediated transport
|
GO:0016192 |
335 |
0.022
|
|
|
organelle fusion
|
GO:0048284 |
85 |
0.021
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
294 |
0.021
|
|
|
cellular response to organic substance
|
GO:0071310 |
159 |
0.021
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
59 |
0.021
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
332 |
0.021
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
124 |
0.021
|
|
|
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031145 |
35 |
0.021
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
68 |
0.021
|
Human |
|
cellular carbohydrate metabolic process
|
GO:0044262 |
135 |
0.021
|
|
|
amine metabolic process
|
GO:0009308 |
51 |
0.020
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
380 |
0.020
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
28 |
0.020
|
|
|
regulation of localization
|
GO:0032879 |
127 |
0.020
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
291 |
0.020
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
95 |
0.019
|
|
|
response to oxygen containing compound
|
GO:1901700 |
61 |
0.019
|
|
|
membrane lipid metabolic process
|
GO:0006643 |
67 |
0.019
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
63 |
0.019
|
|
|
regulation of cell cycle process
|
GO:0010564 |
150 |
0.019
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
328 |
0.018
|
|
|
dna recombination
|
GO:0006310 |
172 |
0.018
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.018
|
|
|
establishment of protein localization
|
GO:0045184 |
367 |
0.018
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
312 |
0.018
|
|
|
protein transport
|
GO:0015031 |
345 |
0.018
|
|
|
cellular response to starvation
|
GO:0009267 |
90 |
0.018
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
195 |
0.018
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
57 |
0.018
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
335 |
0.017
|
|
|
negative regulation of proteasomal protein catabolic process
|
GO:1901799 |
25 |
0.017
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
237 |
0.017
|
|
|
rna localization
|
GO:0006403 |
112 |
0.017
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
147 |
0.017
|
|
|
nucleotide catabolic process
|
GO:0009166 |
330 |
0.017
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
91 |
0.016
|
|
|
spindle assembly checkpoint
|
GO:0071173 |
23 |
0.016
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
64 |
0.016
|
|
|
negative regulation of protein processing
|
GO:0010955 |
33 |
0.016
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
108 |
0.016
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
27 |
0.016
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
137 |
0.016
|
|
|
transmembrane transport
|
GO:0055085 |
349 |
0.016
|
|
|
regulation of cellular localization
|
GO:0060341 |
50 |
0.015
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
225 |
0.015
|
|
|
recombinational repair
|
GO:0000725 |
64 |
0.015
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
38 |
0.015
|
Human |
|
small molecule biosynthetic process
|
GO:0044283 |
258 |
0.015
|
|
|
rna catabolic process
|
GO:0006401 |
118 |
0.015
|
|
|
mitotic spindle elongation
|
GO:0000022 |
14 |
0.015
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
389 |
0.014
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
50 |
0.014
|
|
|
negative regulation of cell division
|
GO:0051782 |
66 |
0.014
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
49 |
0.014
|
|
|
dna damage checkpoint
|
GO:0000077 |
29 |
0.014
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
314 |
0.014
|
|
|
mitotic cytokinesis
|
GO:0000281 |
58 |
0.014
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
43 |
0.014
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
43 |
0.014
|
|
|
cellular biogenic amine metabolic process
|
GO:0006576 |
37 |
0.013
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
289 |
0.013
|
|
|
nucleoside catabolic process
|
GO:0009164 |
335 |
0.013
|
|
|
glucan biosynthetic process
|
GO:0009250 |
26 |
0.013
|
|
|
metal ion homeostasis
|
GO:0055065 |
79 |
0.013
|
|
|
cellular response to external stimulus
|
GO:0071496 |
150 |
0.013
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
327 |
0.013
|
|
|
lipid biosynthetic process
|
GO:0008610 |
170 |
0.013
|
|
|
spindle elongation
|
GO:0051231 |
14 |
0.013
|
|
|
organophosphate catabolic process
|
GO:0046434 |
338 |
0.013
|
|
|
regulation of mitotic sister chromatid segregation
|
GO:0033047 |
30 |
0.013
|
|
|
establishment of organelle localization
|
GO:0051656 |
96 |
0.013
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
178 |
0.013
|
|
|
glucose metabolic process
|
GO:0006006 |
65 |
0.013
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
31 |
0.013
|
|
|
negative regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903051 |
27 |
0.013
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
332 |
0.013
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
398 |
0.013
|
|
|
dephosphorylation
|
GO:0016311 |
127 |
0.012
|
|
|
regulation of exit from mitosis
|
GO:0007096 |
29 |
0.012
|
|
|
chromosome organization involved in meiosis
|
GO:0070192 |
32 |
0.012
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
135 |
0.012
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
44 |
0.012
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
327 |
0.012
|
|
|
mrna metabolic process
|
GO:0016071 |
269 |
0.012
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
384 |
0.012
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
99 |
0.012
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
331 |
0.012
|
|
|
regulation of mitotic metaphase anaphase transition
|
GO:0030071 |
27 |
0.012
|
|
|
regulation of protein maturation
|
GO:1903317 |
34 |
0.012
|
|
|
metaphase anaphase transition of mitotic cell cycle
|
GO:0007091 |
28 |
0.011
|
|
|
cellular component disassembly
|
GO:0022411 |
86 |
0.011
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
112 |
0.011
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
93 |
0.011
|
|
|
organelle localization
|
GO:0051640 |
128 |
0.011
|
|
|
regulation of microtubule based process
|
GO:0032886 |
32 |
0.011
|
|
|
cellular amine metabolic process
|
GO:0044106 |
51 |
0.011
|
|
|
dna repair
|
GO:0006281 |
236 |
0.011
|
|
|
dna integrity checkpoint
|
GO:0031570 |
41 |
0.011
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
327 |
0.011
|
|
|
protein localization to chromosome
|
GO:0034502 |
28 |
0.011
|
|
|
response to organic substance
|
GO:0010033 |
182 |
0.010
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
116 |
0.010
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
115 |
0.010
|
|
|
mrna processing
|
GO:0006397 |
185 |
0.010
|
|