Saccharomyces cerevisiae

110 known processes

SPT16 (YGL207W)

Spt16p

(Aliases: CDC68,SSF1)

SPT16 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.995
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.991
chromatin organization GO:0006325 242 0.989
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 19 0.984
transcription initiation from rna polymerase ii promoter GO:0006367 55 0.980
chromatin assembly or disassembly GO:0006333 60 0.965
protein phosphorylation GO:0006468 197 0.957
dna templated transcription elongation GO:0006354 91 0.951
dna templated transcription initiation GO:0006352 71 0.935
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.921
regulation of chromatin organization GO:1902275 23 0.903
phosphorylation GO:0016310 291 0.898
regulation of chromatin modification GO:1903308 23 0.898
nucleotide excision repair GO:0006289 50 0.875
negative regulation of transcription dna templated GO:0045892 258 0.870
protein modification by small protein conjugation or removal GO:0070647 172 0.869
positive regulation of macromolecule metabolic process GO:0010604 394 0.868
dna repair GO:0006281 236 0.843
protein catabolic process GO:0030163 221 0.843
positive regulation of biosynthetic process GO:0009891 336 0.831
cell cycle phase transition GO:0044770 144 0.822
regulation of dna templated transcription initiation GO:2000142 19 0.820
negative regulation of biosynthetic process GO:0009890 312 0.793
negative regulation of cellular metabolic process GO:0031324 407 0.775
regulation of histone modification GO:0031056 18 0.762
negative regulation of rna biosynthetic process GO:1902679 260 0.749
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 11 0.747
transcription elongation from rna polymerase ii promoter GO:0006368 81 0.735
dna replication GO:0006260 147 0.734
negative regulation of cell cycle process GO:0010948 86 0.731
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.702
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.699
chromatin assembly GO:0031497 35 0.698
regulation of chromosome organization GO:0033044 66 0.697
positive regulation of transcription dna templated GO:0045893 286 0.689
dna packaging GO:0006323 55 0.688
positive regulation of dna templated transcription initiation GO:2000144 13 0.680
negative regulation of cellular biosynthetic process GO:0031327 312 0.679
cellular amino acid metabolic process GO:0006520 225 0.673
regulation of response to dna damage stimulus GO:2001020 17 0.635
negative regulation of cell cycle GO:0045786 91 0.633
negative regulation of macromolecule metabolic process GO:0010605 375 0.613
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 13 0.612
positive regulation of dna templated transcription elongation GO:0032786 42 0.609
negative regulation of nucleic acid templated transcription GO:1903507 260 0.603
regulation of transcription from rna polymerase i promoter GO:0006356 36 0.598
regulation of response to stimulus GO:0048583 157 0.586
organic acid metabolic process GO:0006082 352 0.567
anatomical structure development GO:0048856 160 0.566
Worm
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 38 0.562
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.557
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.553
protein complex biogenesis GO:0070271 314 0.550
positive regulation of gene expression GO:0010628 321 0.532
cell cycle g1 s phase transition GO:0044843 64 0.525
developmental process GO:0032502 261 0.517
Worm
protein dna complex assembly GO:0065004 105 0.510
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 40 0.508
protein dna complex subunit organization GO:0071824 153 0.503
regulation of dna metabolic process GO:0051052 100 0.500
mitotic cell cycle GO:0000278 306 0.485
mitotic cell cycle phase transition GO:0044772 141 0.482
gene silencing GO:0016458 151 0.467
cellular protein catabolic process GO:0044257 213 0.462
regulation of cell cycle phase transition GO:1901987 70 0.461
transcription from rna polymerase i promoter GO:0006360 63 0.458
negative regulation of gene expression GO:0010629 312 0.457
histone modification GO:0016570 119 0.449
negative regulation of mitotic cell cycle GO:0045930 63 0.445
chromatin modification GO:0016568 200 0.438
positive regulation of rna biosynthetic process GO:1902680 286 0.437
regulation of cell cycle process GO:0010564 150 0.410
protein ubiquitination GO:0016567 118 0.407
regulation of protein modification process GO:0031399 110 0.401
regulation of dna templated transcription elongation GO:0032784 44 0.385
positive regulation of cellular component biogenesis GO:0044089 45 0.375
proteolysis GO:0006508 268 0.367
mitotic cell cycle process GO:1903047 294 0.361
positive regulation of nucleic acid templated transcription GO:1903508 286 0.361
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.360
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.358
dna templated transcriptional preinitiation complex assembly GO:0070897 51 0.340
covalent chromatin modification GO:0016569 119 0.340
positive regulation of cellular component organization GO:0051130 116 0.329
regulation of cellular component organization GO:0051128 334 0.328
regulation of mitotic cell cycle phase transition GO:1901990 68 0.327
macromolecule catabolic process GO:0009057 383 0.319
regulation of cell cycle GO:0051726 195 0.317
single organism developmental process GO:0044767 258 0.313
Worm
positive regulation of cellular biosynthetic process GO:0031328 336 0.312
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 40 0.306
regulation of signaling GO:0023051 119 0.304
protein modification by small protein conjugation GO:0032446 144 0.299
multi organism process GO:0051704 233 0.295
anatomical structure morphogenesis GO:0009653 160 0.288
carboxylic acid metabolic process GO:0019752 338 0.288
regulation of cellular protein metabolic process GO:0032268 232 0.267
regulation of protein metabolic process GO:0051246 237 0.266
positive regulation of rna metabolic process GO:0051254 294 0.266
histone h3 k4 methylation GO:0051568 18 0.251
histone h2b conserved c terminal lysine ubiquitination GO:0071894 6 0.249
cellular macromolecule catabolic process GO:0044265 363 0.247
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.247
transcription coupled nucleotide excision repair GO:0006283 16 0.242
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.237
regulation of dna repair GO:0006282 14 0.229
regulation of cellular ketone metabolic process GO:0010565 42 0.216
chromatin silencing at telomere GO:0006348 84 0.212
regulation of protein complex assembly GO:0043254 77 0.200
regulation of cellular amine metabolic process GO:0033238 21 0.195
transcription from rna polymerase iii promoter GO:0006383 40 0.192
dna dependent dna replication GO:0006261 115 0.191
nucleosome organization GO:0034728 63 0.190
amine metabolic process GO:0009308 51 0.188
negative regulation of cellular protein metabolic process GO:0032269 85 0.187
regulation of protein ubiquitination GO:0031396 20 0.184
macromolecule methylation GO:0043414 85 0.180
regulation of mitotic cell cycle GO:0007346 107 0.178
cellular ketone metabolic process GO:0042180 63 0.176
cellular amine metabolic process GO:0044106 51 0.175
regulation of cell communication GO:0010646 124 0.174
reproductive process GO:0022414 248 0.174
cell communication GO:0007154 345 0.168
negative regulation of rna metabolic process GO:0051253 262 0.161
g1 s transition of mitotic cell cycle GO:0000082 64 0.160
developmental process involved in reproduction GO:0003006 159 0.159
dna templated transcription termination GO:0006353 42 0.156
single organism signaling GO:0044700 208 0.154
histone methylation GO:0016571 28 0.154
positive regulation of cell communication GO:0010647 28 0.151
cellular developmental process GO:0048869 191 0.148
positive regulation of phosphate metabolic process GO:0045937 147 0.147
regulation of gene expression epigenetic GO:0040029 147 0.145
regulation of transcription by chromatin organization GO:0034401 19 0.140
negative regulation of cell cycle phase transition GO:1901988 59 0.134
mrna processing GO:0006397 185 0.124
regulation of transcription coupled nucleotide excision repair GO:0090262 7 0.121
positive regulation of protein phosphorylation GO:0001934 28 0.121
regulation of nucleotide excision repair GO:2000819 7 0.121
vesicle mediated transport GO:0016192 335 0.121
regulation of response to stress GO:0080134 57 0.120
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.118
protein localization to organelle GO:0033365 337 0.117
protein complex assembly GO:0006461 302 0.114
single organism reproductive process GO:0044702 159 0.113
negative regulation of gene expression epigenetic GO:0045814 147 0.108
sexual reproduction GO:0019953 216 0.107
negative regulation of chromosome organization GO:2001251 39 0.107
regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0000083 27 0.107
dna conformation change GO:0071103 98 0.106
negative regulation of organelle organization GO:0010639 103 0.099
chromatin remodeling GO:0006338 80 0.098
regulation of gene silencing GO:0060968 41 0.098
regulation of phosphorus metabolic process GO:0051174 230 0.096
autophagy GO:0006914 106 0.096
oxoacid metabolic process GO:0043436 351 0.095
positive regulation of phosphorus metabolic process GO:0010562 147 0.094
phosphorylation of rna polymerase ii c terminal domain GO:0070816 20 0.091
positive regulation of protein modification process GO:0031401 49 0.087
regulation of dna replication GO:0006275 51 0.087
cellular response to nutrient levels GO:0031669 144 0.086
positive regulation of protein metabolic process GO:0051247 93 0.085
positive regulation of transcription from rna polymerase i promoter GO:0045943 19 0.085
reproductive process in single celled organism GO:0022413 145 0.083
posttranscriptional regulation of gene expression GO:0010608 115 0.083
protein maturation GO:0051604 76 0.080
regulation of cellular response to stress GO:0080135 50 0.080
multi organism reproductive process GO:0044703 216 0.079
histone lysine methylation GO:0034968 26 0.079
cellular response to external stimulus GO:0071496 150 0.078
intracellular signal transduction GO:0035556 112 0.074
regulation of molecular function GO:0065009 320 0.074
negative regulation of protein metabolic process GO:0051248 85 0.073
meiotic cell cycle GO:0051321 272 0.072
dna replication independent nucleosome organization GO:0034724 9 0.072
chromosome segregation GO:0007059 159 0.068
negative regulation of cellular component organization GO:0051129 109 0.066
cell cycle checkpoint GO:0000075 82 0.064
positive regulation of phosphorylation GO:0042327 33 0.064
regulation of histone h2b ubiquitination GO:2001166 6 0.063
histone ubiquitination GO:0016574 17 0.062
macromolecular complex disassembly GO:0032984 80 0.059
methylation GO:0032259 101 0.058
positive regulation of chromatin modification GO:1903310 13 0.056
dna strand elongation involved in dna replication GO:0006271 26 0.056
negative regulation of cell communication GO:0010648 33 0.054
nuclear division GO:0000280 263 0.054
cellular response to dna damage stimulus GO:0006974 287 0.053
meiotic nuclear division GO:0007126 163 0.052
double strand break repair GO:0006302 105 0.049
cell cycle g2 m phase transition GO:0044839 39 0.049
regulation of phosphate metabolic process GO:0019220 230 0.048
protein processing GO:0016485 64 0.048
regulation of histone ubiquitination GO:0033182 7 0.047
mrna metabolic process GO:0016071 269 0.047
regulation of organelle organization GO:0033043 243 0.045
regulation of cellular amino acid metabolic process GO:0006521 16 0.045
cellular component disassembly GO:0022411 86 0.044
regulation of chromatin silencing GO:0031935 39 0.043
regulation of transcription elongation from rna polymerase i promoter GO:2001207 7 0.043
regulation of protein modification by small protein conjugation or removal GO:1903320 29 0.043
response to abiotic stimulus GO:0009628 159 0.043
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.043
reproduction of a single celled organism GO:0032505 191 0.042
mitotic nuclear division GO:0007067 131 0.040
regulation of proteolysis GO:0030162 44 0.040
peptidyl amino acid modification GO:0018193 116 0.039
response to topologically incorrect protein GO:0035966 38 0.039
signaling GO:0023052 208 0.039
regulation of chromatin silencing at telomere GO:0031938 27 0.038
regulation of dna dependent dna replication GO:0090329 37 0.037
nucleoside monophosphate metabolic process GO:0009123 267 0.036
transcriptional start site selection at rna polymerase ii promoter GO:0001174 7 0.036
regulation of protein phosphorylation GO:0001932 75 0.036
purine nucleoside monophosphate metabolic process GO:0009126 262 0.034
positive regulation of cellular protein metabolic process GO:0032270 89 0.034
glycerolipid biosynthetic process GO:0045017 71 0.034
transcription elongation from rna polymerase i promoter GO:0006362 10 0.032
modification dependent protein catabolic process GO:0019941 181 0.032
ubiquitin dependent protein catabolic process GO:0006511 181 0.032
protein complex disassembly GO:0043241 70 0.032
carbohydrate derivative metabolic process GO:1901135 549 0.031
chromatin silencing GO:0006342 147 0.031
peptidyl lysine methylation GO:0018022 24 0.030
organelle fission GO:0048285 272 0.030
protein alkylation GO:0008213 48 0.030
meiotic cell cycle process GO:1903046 229 0.030
carbohydrate derivative catabolic process GO:1901136 339 0.030
regulation of histone methylation GO:0031060 8 0.030
filamentous growth GO:0030447 124 0.030
atp catabolic process GO:0006200 224 0.029
regulation of histone acetylation GO:0035065 7 0.029
regulation of intracellular signal transduction GO:1902531 78 0.029
cell surface receptor signaling pathway GO:0007166 38 0.029
positive regulation of histone modification GO:0031058 12 0.028
response to extracellular stimulus GO:0009991 156 0.027
rrna transcription GO:0009303 31 0.027
regulation of signal transduction GO:0009966 114 0.027
negative regulation of nuclear division GO:0051784 62 0.027
lipid metabolic process GO:0006629 269 0.027
positive regulation of protein complex assembly GO:0031334 39 0.027
cell cycle dna replication GO:0044786 36 0.027
regulation of transcription from rna polymerase iii promoter GO:0006359 16 0.026
regulation of phosphorylation GO:0042325 86 0.026
negative regulation of protein modification process GO:0031400 37 0.026
regulation of dna templated transcription in response to stress GO:0043620 51 0.025
glycerophospholipid biosynthetic process GO:0046474 68 0.025
negative regulation of dna metabolic process GO:0051053 36 0.023
cellular response to extracellular stimulus GO:0031668 150 0.022
positive regulation of kinase activity GO:0033674 24 0.022
single organism cellular localization GO:1902580 375 0.022
protein targeting GO:0006605 272 0.022
regulation of dna recombination GO:0000018 24 0.022
chromatin silencing at rdna GO:0000183 32 0.021
cellular response to chemical stimulus GO:0070887 315 0.021
sexual sporulation GO:0034293 113 0.021
small molecule biosynthetic process GO:0044283 258 0.021
microtubule based process GO:0007017 117 0.021
positive regulation of cellular catabolic process GO:0031331 128 0.020
signal transduction GO:0007165 208 0.020
snorna processing GO:0043144 34 0.020
regulation of protein catabolic process GO:0042176 40 0.020
regulation of histone h3 k4 methylation GO:0051569 5 0.020
base excision repair GO:0006284 14 0.020
positive regulation of catabolic process GO:0009896 135 0.019
regulation of transcription from rna polymerase ii promoter by glucose GO:0000430 12 0.019
positive regulation of cellular amine metabolic process GO:0033240 10 0.018
sporulation resulting in formation of a cellular spore GO:0030435 129 0.018
positive regulation of cell cycle process GO:0090068 31 0.017
organonitrogen compound catabolic process GO:1901565 404 0.017
protein localization to vacuole GO:0072665 92 0.017
nucleosome mobilization GO:0042766 11 0.017
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 26 0.017
ribonucleoside triphosphate metabolic process GO:0009199 356 0.017
nucleosome positioning GO:0016584 10 0.017
mating type determination GO:0007531 32 0.017
regulation of catabolic process GO:0009894 199 0.017
positive regulation of catalytic activity GO:0043085 178 0.017
heterocycle catabolic process GO:0046700 494 0.017
cell differentiation GO:0030154 161 0.016
maintenance of dna repeat elements GO:0043570 20 0.016
protein modification by small protein removal GO:0070646 29 0.016
regulation of nuclear division GO:0051783 103 0.016
regulation of histone exchange GO:1900049 4 0.015
regulation of catalytic activity GO:0050790 307 0.015
regulation of mating type switching GO:0031494 7 0.015
protein methylation GO:0006479 48 0.015
dna duplex unwinding GO:0032508 42 0.015
sporulation GO:0043934 132 0.015
atp metabolic process GO:0046034 251 0.014
dna unwinding involved in dna replication GO:0006268 13 0.014
phosphorylation of rna polymerase ii c terminal domain serine 2 residues GO:0071619 4 0.014
phosphatidylcholine biosynthetic process GO:0006656 18 0.014
g2 m transition of mitotic cell cycle GO:0000086 38 0.014
dna replication initiation GO:0006270 48 0.014
positive regulation of protein catabolic process GO:0045732 9 0.014
glycerophospholipid metabolic process GO:0006650 98 0.014
sister chromatid segregation GO:0000819 93 0.013
organophosphate catabolic process GO:0046434 338 0.013
positive regulation of chromosome organization GO:2001252 20 0.013
protein monoubiquitination GO:0006513 13 0.013
negative regulation of chromatin modification GO:1903309 9 0.013
regulation of biological quality GO:0065008 391 0.013
negative regulation of signaling GO:0023057 30 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.013
regulation of cellular catabolic process GO:0031329 195 0.013
regulation of phosphorylation of rna polymerase ii c terminal domain GO:1901407 5 0.013
poly a mrna export from nucleus GO:0016973 24 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 7 0.012
proteasomal protein catabolic process GO:0010498 141 0.012
response to nutrient GO:0007584 52 0.012
nucleoside catabolic process GO:0009164 335 0.012
organic hydroxy compound biosynthetic process GO:1901617 81 0.012
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter GO:0072366 10 0.012
negative regulation of carbohydrate metabolic process GO:0045912 17 0.012
nucleosome assembly GO:0006334 16 0.012
negative regulation of mitosis GO:0045839 39 0.012
glycosyl compound catabolic process GO:1901658 335 0.011
negative regulation of transcription from rna polymerase ii promoter by glucose GO:0000433 10 0.011
dna recombination GO:0006310 172 0.011
cellular metal ion homeostasis GO:0006875 78 0.011
positive regulation of signal transduction GO:0009967 20 0.011
organonitrogen compound biosynthetic process GO:1901566 314 0.011
positive regulation of transcription elongation from rna polymerase i promoter GO:2001209 7 0.011
negative regulation of cell division GO:0051782 66 0.011
purine ribonucleoside metabolic process GO:0046128 380 0.011
ribonucleoside catabolic process GO:0042454 332 0.011
oligosaccharide metabolic process GO:0009311 35 0.011
organic cyclic compound catabolic process GO:1901361 499 0.011
negative regulation of catalytic activity GO:0043086 60 0.010
establishment of protein localization GO:0045184 367 0.010
secretion by cell GO:0032940 50 0.010
response to uv GO:0009411 4 0.010
regulation of phosphorylation of rna polymerase ii c terminal domain serine 2 residues GO:2001163 4 0.010

SPT16 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org