Saccharomyces cerevisiae

66 known processes

MPH1 (YIR002C)

Mph1p

MPH1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 236 0.711
cellular response to dna damage stimulus GO:0006974 287 0.640
cellular response to organic substance GO:0071310 159 0.258
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.257
organic cyclic compound catabolic process GO:1901361 499 0.251
Yeast
establishment of protein localization GO:0045184 367 0.245
regulation of cellular component organization GO:0051128 334 0.235
nuclear division GO:0000280 263 0.230
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.194
protein targeting GO:0006605 272 0.192
single organism cellular localization GO:1902580 375 0.184
fungal type cell wall organization or biogenesis GO:0071852 169 0.178
nucleobase containing compound catabolic process GO:0034655 479 0.174
Yeast
dna recombination GO:0006310 172 0.170
recombinational repair GO:0000725 64 0.164
cellular nitrogen compound catabolic process GO:0044270 494 0.162
Yeast
regulation of biological quality GO:0065008 391 0.152
organelle fission GO:0048285 272 0.150
cellular response to chemical stimulus GO:0070887 315 0.146
macromolecule catabolic process GO:0009057 383 0.146
regulation of mitotic cell cycle GO:0007346 107 0.142
reproductive process GO:0022414 248 0.138
filamentous growth GO:0030447 124 0.132
single organism catabolic process GO:0044712 619 0.127
Yeast
protein localization to organelle GO:0033365 337 0.125
multi organism cellular process GO:0044764 120 0.123
response to organic substance GO:0010033 182 0.107
protein catabolic process GO:0030163 221 0.104
proteolysis GO:0006508 268 0.104
modification dependent protein catabolic process GO:0019941 181 0.102
intracellular protein transport GO:0006886 319 0.102
regulation of chromosome organization GO:0033044 66 0.101
multi organism reproductive process GO:0044703 216 0.101
homeostatic process GO:0042592 227 0.100
protein transport GO:0015031 345 0.090
membrane organization GO:0061024 276 0.088
heterocycle catabolic process GO:0046700 494 0.087
Yeast
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.086
positive regulation of macromolecule metabolic process GO:0010604 394 0.085
cellular macromolecule catabolic process GO:0044265 363 0.083
telomere maintenance via recombination GO:0000722 32 0.081
response to chemical GO:0042221 390 0.081
sexual reproduction GO:0019953 216 0.081
nuclear transport GO:0051169 165 0.078
regulation of catabolic process GO:0009894 199 0.077
mitotic cell cycle GO:0000278 306 0.077
ribonucleoside triphosphate catabolic process GO:0009203 327 0.076
Yeast
establishment of protein localization to organelle GO:0072594 278 0.075
meiotic cell cycle process GO:1903046 229 0.075
carbohydrate metabolic process GO:0005975 252 0.075
aromatic compound catabolic process GO:0019439 491 0.075
Yeast
single organism signaling GO:0044700 208 0.070
nucleotide catabolic process GO:0009166 330 0.069
Yeast
filamentous growth of a population of unicellular organisms GO:0044182 109 0.069
cell wall organization or biogenesis GO:0071554 190 0.068
purine nucleoside triphosphate catabolic process GO:0009146 329 0.067
Yeast
cell wall organization GO:0071555 146 0.066
multi organism process GO:0051704 233 0.066
regulation of molecular function GO:0065009 320 0.065
external encapsulating structure organization GO:0045229 146 0.065
cellular protein catabolic process GO:0044257 213 0.064
negative regulation of cellular metabolic process GO:0031324 407 0.061
regulation of cellular protein metabolic process GO:0032268 232 0.061
organonitrogen compound catabolic process GO:1901565 404 0.060
Yeast
meiotic nuclear division GO:0007126 163 0.056
small molecule biosynthetic process GO:0044283 258 0.056
regulation of protein metabolic process GO:0051246 237 0.056
single organism reproductive process GO:0044702 159 0.055
nucleoside triphosphate catabolic process GO:0009143 329 0.055
Yeast
cellular response to osmotic stress GO:0071470 50 0.055
regulation of protein catabolic process GO:0042176 40 0.054
positive regulation of gene expression GO:0010628 321 0.054
nucleocytoplasmic transport GO:0006913 163 0.054
regulation of cell cycle process GO:0010564 150 0.054
meiotic cell cycle GO:0051321 272 0.053
cell cycle phase transition GO:0044770 144 0.053
ribonucleotide catabolic process GO:0009261 327 0.052
Yeast
mrna processing GO:0006397 185 0.051
proteasomal protein catabolic process GO:0010498 141 0.051
reproduction of a single celled organism GO:0032505 191 0.050
negative regulation of macromolecule metabolic process GO:0010605 375 0.050
fungal type cell wall organization GO:0031505 145 0.049
regulation of catalytic activity GO:0050790 307 0.048
cytoskeleton organization GO:0007010 230 0.046
positive regulation of hydrolase activity GO:0051345 112 0.046
purine nucleotide catabolic process GO:0006195 328 0.045
Yeast
regulation of cellular catabolic process GO:0031329 195 0.043
single organism carbohydrate metabolic process GO:0044723 237 0.041
ribose phosphate metabolic process GO:0019693 384 0.041
Yeast
mitotic cell cycle process GO:1903047 294 0.041
regulation of cellular response to stress GO:0080135 50 0.041
regulation of response to stimulus GO:0048583 157 0.041
negative regulation of cell cycle GO:0045786 91 0.040
non recombinational repair GO:0000726 33 0.040
telomere maintenance GO:0000723 74 0.040
regulation of organelle organization GO:0033043 243 0.039
conjugation GO:0000746 107 0.039
response to oxidative stress GO:0006979 99 0.039
signaling GO:0023052 208 0.039
negative regulation of proteolysis GO:0045861 33 0.038
developmental process GO:0032502 261 0.038
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 36 0.038
purine nucleoside catabolic process GO:0006152 330 0.038
Yeast
positive regulation of organelle organization GO:0010638 85 0.038
mrna metabolic process GO:0016071 269 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.037
telomere organization GO:0032200 75 0.036
intracellular signal transduction GO:0035556 112 0.036
pseudohyphal growth GO:0007124 75 0.035
regulation of transport GO:0051049 85 0.035
nucleobase containing small molecule metabolic process GO:0055086 491 0.034
Yeast
cellular response to pheromone GO:0071444 88 0.034
response to pheromone GO:0019236 92 0.034
ubiquitin dependent protein catabolic process GO:0006511 181 0.033
regulation of cellular protein catabolic process GO:1903362 36 0.033
negative regulation of cellular protein catabolic process GO:1903363 27 0.033
organelle inheritance GO:0048308 51 0.033
carbohydrate derivative metabolic process GO:1901135 549 0.033
Yeast
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.033
negative regulation of chromosome organization GO:2001251 39 0.032
ribonucleoside catabolic process GO:0042454 332 0.032
Yeast
response to abiotic stimulus GO:0009628 159 0.032
single organism developmental process GO:0044767 258 0.031
dna catabolic process GO:0006308 42 0.031
regulation of cell division GO:0051302 113 0.031
double strand break repair via homologous recombination GO:0000724 54 0.030
nuclear export GO:0051168 124 0.030
negative regulation of organelle organization GO:0010639 103 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.030
negative regulation of gene expression GO:0010629 312 0.029
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.029
negative regulation of protein processing GO:0010955 33 0.029
regulation of mitosis GO:0007088 65 0.029
positive regulation of biosynthetic process GO:0009891 336 0.029
positive regulation of phosphorus metabolic process GO:0010562 147 0.029
positive regulation of phosphate metabolic process GO:0045937 147 0.029
positive regulation of transcription dna templated GO:0045893 286 0.029
cellular response to abiotic stimulus GO:0071214 62 0.029
regulation of proteolysis GO:0030162 44 0.028
regulation of translation GO:0006417 89 0.028
nucleoside triphosphate metabolic process GO:0009141 364 0.028
Yeast
purine ribonucleoside metabolic process GO:0046128 380 0.028
Yeast
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.028
cell differentiation GO:0030154 161 0.028
signal transduction GO:0007165 208 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.027
cell communication GO:0007154 345 0.027
regulation of localization GO:0032879 127 0.027
purine nucleoside triphosphate metabolic process GO:0009144 356 0.027
Yeast
positive regulation of cellular biosynthetic process GO:0031328 336 0.027
growth GO:0040007 157 0.027
single organism membrane organization GO:0044802 275 0.027
positive regulation of nucleic acid templated transcription GO:1903508 286 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.026
Yeast
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.026
positive regulation of catalytic activity GO:0043085 178 0.026
carboxylic acid metabolic process GO:0019752 338 0.026
posttranscriptional regulation of gene expression GO:0010608 115 0.026
response to organic cyclic compound GO:0014070 1 0.026
glucose metabolic process GO:0006006 65 0.026
protein localization to nucleus GO:0034504 74 0.025
purine nucleoside metabolic process GO:0042278 380 0.025
Yeast
purine ribonucleotide catabolic process GO:0009154 327 0.025
Yeast
modification dependent macromolecule catabolic process GO:0043632 203 0.024
negative regulation of protein maturation GO:1903318 33 0.024
ribonucleoside monophosphate catabolic process GO:0009158 224 0.024
Yeast
regulation of hydrolase activity GO:0051336 133 0.024
regulation of response to stress GO:0080134 57 0.024
aging GO:0007568 71 0.024
purine nucleoside monophosphate catabolic process GO:0009128 224 0.024
Yeast
positive regulation of protein metabolic process GO:0051247 93 0.023
response to osmotic stress GO:0006970 83 0.023
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 35 0.023
regulation of protein maturation GO:1903317 34 0.023
response to temperature stimulus GO:0009266 74 0.023
regulation of mitotic cell cycle phase transition GO:1901990 68 0.023
organelle fusion GO:0048284 85 0.023
establishment of protein localization to vacuole GO:0072666 91 0.023
regulation of purine nucleotide catabolic process GO:0033121 106 0.023
carbohydrate derivative catabolic process GO:1901136 339 0.022
Yeast
dna replication GO:0006260 147 0.022
nucleoside monophosphate metabolic process GO:0009123 267 0.022
Yeast
oxidation reduction process GO:0055114 353 0.022
positive regulation of rna metabolic process GO:0051254 294 0.022
nucleoside monophosphate catabolic process GO:0009125 224 0.022
Yeast
regulation of signal transduction GO:0009966 114 0.022
positive regulation of cellular catabolic process GO:0031331 128 0.022
monosaccharide metabolic process GO:0005996 83 0.022
conjugation with cellular fusion GO:0000747 106 0.022
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 27 0.022
regulation of protein processing GO:0070613 34 0.021
ribonucleotide metabolic process GO:0009259 377 0.021
Yeast
nucleoside catabolic process GO:0009164 335 0.021
Yeast
lipid biosynthetic process GO:0008610 170 0.021
cellular component disassembly GO:0022411 86 0.021
cell growth GO:0016049 89 0.021
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.021
generation of precursor metabolites and energy GO:0006091 147 0.021
purine ribonucleoside catabolic process GO:0046130 330 0.021
Yeast
invasive filamentous growth GO:0036267 65 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 100 0.020
developmental process involved in reproduction GO:0003006 159 0.020
positive regulation of rna biosynthetic process GO:1902680 286 0.020
positive regulation of cellular component organization GO:0051130 116 0.020
vacuolar transport GO:0007034 145 0.020
negative regulation of signaling GO:0023057 30 0.020
regulation of sister chromatid segregation GO:0033045 30 0.019
regulation of cell cycle phase transition GO:1901987 70 0.019
regulation of cell wall organization or biogenesis GO:1903338 18 0.019
establishment of organelle localization GO:0051656 96 0.019
positive regulation of catabolic process GO:0009896 135 0.019
protein maturation GO:0051604 76 0.019
cellular response to heat GO:0034605 53 0.019
negative regulation of cellular protein metabolic process GO:0032269 85 0.019
gene silencing GO:0016458 151 0.018
regulation of chromosome segregation GO:0051983 44 0.018
mitotic nuclear division GO:0007067 131 0.018
membrane fusion GO:0061025 73 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.018
Yeast
positive regulation of nucleotide metabolic process GO:0045981 101 0.018
nucleoside phosphate catabolic process GO:1901292 331 0.018
Yeast
ribonucleoside triphosphate metabolic process GO:0009199 356 0.017
Yeast
organophosphate catabolic process GO:0046434 338 0.017
Yeast
purine containing compound catabolic process GO:0072523 332 0.017
Yeast
cell division GO:0051301 205 0.017
organic acid biosynthetic process GO:0016053 152 0.017
cellular amino acid metabolic process GO:0006520 225 0.017
cellular ion homeostasis GO:0006873 112 0.016
negative regulation of gene expression epigenetic GO:0045814 147 0.016
atp catabolic process GO:0006200 224 0.016
Yeast
negative regulation of mitotic cell cycle GO:0045930 63 0.016
purine nucleotide metabolic process GO:0006163 376 0.016
Yeast
response to pheromone involved in conjugation with cellular fusion GO:0000749 74 0.016
cellular developmental process GO:0048869 191 0.016
double strand break repair via nonhomologous end joining GO:0006303 27 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.016
Yeast
nucleoside metabolic process GO:0009116 394 0.016
Yeast
glycosyl compound metabolic process GO:1901657 398 0.016
Yeast
g2 m transition of mitotic cell cycle GO:0000086 38 0.015
positive regulation of gtp catabolic process GO:0033126 80 0.015
regulation of cellular localization GO:0060341 50 0.015
organophosphate metabolic process GO:0019637 597 0.015
Yeast
positive regulation of purine nucleotide catabolic process GO:0033123 97 0.015
negative regulation of cell cycle process GO:0010948 86 0.015
positive regulation of cellular protein metabolic process GO:0032270 89 0.015
regulation of cell cycle GO:0051726 195 0.015
cellular response to oxidative stress GO:0034599 94 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.015
Yeast
response to topologically incorrect protein GO:0035966 38 0.015
alcohol metabolic process GO:0006066 112 0.015
regulation of purine nucleotide metabolic process GO:1900542 109 0.015
regulation of response to drug GO:2001023 3 0.015
negative regulation of protein metabolic process GO:0051248 85 0.014
negative regulation of cellular component organization GO:0051129 109 0.014
regulation of nuclear division GO:0051783 103 0.014
mating type switching GO:0007533 28 0.014
reproductive process in single celled organism GO:0022413 145 0.014
sporulation GO:0043934 132 0.014
cell cycle checkpoint GO:0000075 82 0.014
positive regulation of molecular function GO:0044093 185 0.014
glycerophospholipid biosynthetic process GO:0046474 68 0.014
positive regulation of intracellular transport GO:0032388 4 0.014
metal ion homeostasis GO:0055065 79 0.014
protein import into nucleus GO:0006606 55 0.014
double strand break repair GO:0006302 105 0.014
single organism membrane fusion GO:0044801 71 0.013
dephosphorylation GO:0016311 127 0.013
organelle localization GO:0051640 128 0.013
mitotic spindle checkpoint GO:0071174 34 0.013
spindle assembly checkpoint GO:0071173 23 0.013
dna biosynthetic process GO:0071897 33 0.013
alpha amino acid biosynthetic process GO:1901607 91 0.013
ribonucleoside metabolic process GO:0009119 389 0.013
Yeast
purine ribonucleotide metabolic process GO:0009150 372 0.013
Yeast
regulation of signaling GO:0023051 119 0.013
protein complex disassembly GO:0043241 70 0.013
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 24 0.013
anatomical structure morphogenesis GO:0009653 160 0.013
positive regulation of nucleoside metabolic process GO:0045979 97 0.013
protein ubiquitination GO:0016567 118 0.013
protein processing GO:0016485 64 0.013
protein complex biogenesis GO:0070271 314 0.013
negative regulation of protein catabolic process GO:0042177 27 0.012
glycerolipid biosynthetic process GO:0045017 71 0.012
chromatin organization GO:0006325 242 0.012
ribonucleoside monophosphate metabolic process GO:0009161 265 0.012
Yeast
chromosome separation GO:0051304 33 0.012
negative regulation of cell cycle phase transition GO:1901988 59 0.012
alcohol biosynthetic process GO:0046165 75 0.012
transmembrane transport GO:0055085 349 0.012
protein import GO:0017038 122 0.012
protein localization to membrane GO:0072657 102 0.012
organic hydroxy compound biosynthetic process GO:1901617 81 0.012
protein complex assembly GO:0006461 302 0.012
regulation of phosphorus metabolic process GO:0051174 230 0.012
hexose metabolic process GO:0019318 78 0.012
glycosyl compound catabolic process GO:1901658 335 0.012
Yeast
cellular response to topologically incorrect protein GO:0035967 32 0.011
positive regulation of nucleotide catabolic process GO:0030813 97 0.011
regulation of proteasomal protein catabolic process GO:0061136 34 0.011
macromolecular complex disassembly GO:0032984 80 0.011
regulation of nucleotide metabolic process GO:0006140 110 0.011
cell development GO:0048468 107 0.011
base excision repair GO:0006284 14 0.011
positive regulation of apoptotic process GO:0043065 3 0.011
regulation of nucleoside metabolic process GO:0009118 106 0.011
protein modification by small protein conjugation GO:0032446 144 0.011
mitotic cell cycle checkpoint GO:0007093 56 0.011
negative regulation of proteasomal protein catabolic process GO:1901799 25 0.011
cellular carbohydrate metabolic process GO:0044262 135 0.011
response to endoplasmic reticulum stress GO:0034976 23 0.011
anatomical structure homeostasis GO:0060249 74 0.011
organic hydroxy compound metabolic process GO:1901615 125 0.011
peptidyl amino acid modification GO:0018193 116 0.011
positive regulation of cytoplasmic transport GO:1903651 4 0.011
negative regulation of biosynthetic process GO:0009890 312 0.010
nucleotide excision repair GO:0006289 50 0.010
response to heat GO:0009408 69 0.010
regulation of developmental process GO:0050793 30 0.010
regulation of metal ion transport GO:0010959 2 0.010
response to uv GO:0009411 4 0.010
carboxylic acid biosynthetic process GO:0046394 152 0.010
regulation of nucleotide catabolic process GO:0030811 106 0.010
actin filament organization GO:0007015 56 0.010
purine containing compound metabolic process GO:0072521 400 0.010
Yeast

MPH1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
disease of cellular proliferation DOID:14566 0 0.011