Saccharomyces cerevisiae

84 known processes

RFA1 (YAR007C)

Rfa1p

(Aliases: BUF2,RPA1,FUN3)

RFA1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 236 1.000
cellular response to dna damage stimulus GO:0006974 287 0.998
double strand break repair GO:0006302 105 0.983
dna unwinding involved in dna replication GO:0006268 13 0.981
meiotic nuclear division GO:0007126 163 0.980
meiosis i GO:0007127 92 0.977
double strand break repair via homologous recombination GO:0000724 54 0.967
telomere organization GO:0032200 75 0.957
organelle fission GO:0048285 272 0.953
telomere maintenance GO:0000723 74 0.944
telomere maintenance via recombination GO:0000722 32 0.901
meiotic cell cycle GO:0051321 272 0.880
dna replication GO:0006260 147 0.875
meiotic cell cycle process GO:1903046 229 0.859
telomere maintenance via telomerase GO:0007004 21 0.854
dna dependent dna replication GO:0006261 115 0.842
nucleotide excision repair GO:0006289 50 0.825
dna strand elongation GO:0022616 29 0.814
dna recombination GO:0006310 172 0.799
reciprocal dna recombination GO:0035825 54 0.793
recombinational repair GO:0000725 64 0.787
dna strand elongation involved in dna replication GO:0006271 26 0.744
regulation of organelle organization GO:0033043 243 0.721
dna topological change GO:0006265 10 0.677
telomere maintenance via telomere lengthening GO:0010833 22 0.674
macromolecule catabolic process GO:0009057 383 0.673
heteroduplex formation GO:0030491 9 0.633
rna dependent dna replication GO:0006278 25 0.625
nuclear division GO:0000280 263 0.622
aging GO:0007568 71 0.591
lagging strand elongation GO:0006273 10 0.585
anatomical structure homeostasis GO:0060249 74 0.522
dna geometric change GO:0032392 43 0.467
dna conformation change GO:0071103 98 0.421
cell aging GO:0007569 70 0.409
reciprocal meiotic recombination GO:0007131 54 0.406
homeostatic process GO:0042592 227 0.389
protein dna complex assembly GO:0065004 105 0.380
protein modification by small protein conjugation GO:0032446 144 0.335
protein complex assembly GO:0006461 302 0.328
aromatic compound catabolic process GO:0019439 491 0.317
single organism developmental process GO:0044767 258 0.237
Zebrafish Mouse Worm
cellular nitrogen compound catabolic process GO:0044270 494 0.229
microtubule based process GO:0007017 117 0.218
chromosome segregation GO:0007059 159 0.217
cytoskeleton organization GO:0007010 230 0.211
regulation of biological quality GO:0065008 391 0.187
regulation of cell cycle phase transition GO:1901987 70 0.185
heterocycle catabolic process GO:0046700 494 0.177
nucleobase containing compound catabolic process GO:0034655 479 0.173
dna duplex unwinding GO:0032508 42 0.164
regulation of protein metabolic process GO:0051246 237 0.162
regulation of cell cycle g2 m phase transition GO:1902749 8 0.158
regulation of mitotic cell cycle phase transition GO:1901990 68 0.154
protein ubiquitination GO:0016567 118 0.139
developmental process GO:0032502 261 0.135
Zebrafish Mouse Worm
regulation of dna repair GO:0006282 14 0.131
dna catabolic process GO:0006308 42 0.129
replicative cell aging GO:0001302 46 0.128
dna damage checkpoint GO:0000077 29 0.128
mitotic sister chromatid segregation GO:0000070 85 0.123
regulation of dna recombination GO:0000018 24 0.120
regulation of cellular protein metabolic process GO:0032268 232 0.120
negative regulation of cell cycle phase transition GO:1901988 59 0.111
sister chromatid segregation GO:0000819 93 0.104
regulation of dna templated transcription initiation GO:2000142 19 0.101
base excision repair GO:0006284 14 0.098
Human
cellular macromolecule catabolic process GO:0044265 363 0.098
regulation of nuclear division GO:0051783 103 0.095
non recombinational repair GO:0000726 33 0.091
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.090
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.089
regulation of cell division GO:0051302 113 0.088
dna double strand break processing GO:0000729 8 0.086
regulation of cellular component organization GO:0051128 334 0.086
regulation of cell cycle GO:0051726 195 0.081
multi organism process GO:0051704 233 0.079
response to organic cyclic compound GO:0014070 1 0.079
protein complex biogenesis GO:0070271 314 0.078
mitotic nuclear division GO:0007067 131 0.077
chromosome condensation GO:0030261 19 0.075
regulation of response to dna damage stimulus GO:2001020 17 0.074
positive regulation of signal transduction GO:0009967 20 0.073
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.073
organophosphate ester transport GO:0015748 45 0.072
regulation of chromosome organization GO:0033044 66 0.067
regulation of signaling GO:0023051 119 0.067
cell division GO:0051301 205 0.067
rna catabolic process GO:0006401 118 0.066
establishment of protein localization GO:0045184 367 0.065
regulation of protein catabolic process GO:0042176 40 0.061
reproduction of a single celled organism GO:0032505 191 0.060
cellular protein complex assembly GO:0043623 209 0.058
protein polymerization GO:0051258 51 0.058
single organism catabolic process GO:0044712 619 0.057
negative regulation of cell cycle GO:0045786 91 0.057
protein dna complex subunit organization GO:0071824 153 0.057
nucleoside triphosphate metabolic process GO:0009141 364 0.055
mating type switching GO:0007533 28 0.054
negative regulation of cell cycle process GO:0010948 86 0.054
meiotic mismatch repair GO:0000710 9 0.052
nucleobase containing compound transport GO:0015931 124 0.052
macromolecule methylation GO:0043414 85 0.049
ribonucleoside metabolic process GO:0009119 389 0.049
transition metal ion homeostasis GO:0055076 59 0.049
positive regulation of rna biosynthetic process GO:1902680 286 0.049
regulation of protein complex assembly GO:0043254 77 0.049
positive regulation of protein complex assembly GO:0031334 39 0.048
microtubule cytoskeleton organization GO:0000226 109 0.048
regulation of response to stimulus GO:0048583 157 0.044
negative regulation of organelle organization GO:0010639 103 0.044
reproductive process GO:0022414 248 0.043
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.043
meiotic dna double strand break processing GO:0000706 5 0.042
endomembrane system organization GO:0010256 74 0.041
purine ribonucleotide catabolic process GO:0009154 327 0.041
chromosome separation GO:0051304 33 0.041
mitotic dna integrity checkpoint GO:0044774 18 0.040
negative regulation of proteasomal protein catabolic process GO:1901799 25 0.039
negative regulation of protein catabolic process GO:0042177 27 0.038
mitotic cell cycle process GO:1903047 294 0.038
dna catabolic process exonucleolytic GO:0000738 19 0.037
nucleocytoplasmic transport GO:0006913 163 0.037
chromatin organization GO:0006325 242 0.036
organic cyclic compound catabolic process GO:1901361 499 0.036
meiotic chromosome segregation GO:0045132 31 0.035
dna integrity checkpoint GO:0031570 41 0.034
negative regulation of protein processing GO:0010955 33 0.034
protein transport GO:0015031 345 0.034
modification dependent macromolecule catabolic process GO:0043632 203 0.034
endosomal transport GO:0016197 86 0.034
regulation of dna metabolic process GO:0051052 100 0.034
regulation of signal transduction GO:0009966 114 0.034
positive regulation of cellular biosynthetic process GO:0031328 336 0.033
double strand break repair via break induced replication GO:0000727 25 0.033
ribose phosphate metabolic process GO:0019693 384 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.032
cellular protein catabolic process GO:0044257 213 0.031
organelle assembly GO:0070925 118 0.030
protein modification by small protein conjugation or removal GO:0070647 172 0.030
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.029
double strand break repair via single strand annealing GO:0045002 7 0.029
establishment of organelle localization GO:0051656 96 0.029
regulation of cell cycle checkpoint GO:1901976 6 0.028
cellular component disassembly GO:0022411 86 0.028
regulation of meiosis GO:0040020 42 0.028
positive regulation of nucleic acid templated transcription GO:1903508 286 0.027
mitotic cell cycle phase transition GO:0044772 141 0.027
negative regulation of cell division GO:0051782 66 0.026
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 13 0.026
cellular response to abiotic stimulus GO:0071214 62 0.025
ion transport GO:0006811 274 0.025
response to chemical GO:0042221 390 0.025
spindle organization GO:0007051 37 0.024
regulation of mitotic metaphase anaphase transition GO:0030071 27 0.024
cell communication GO:0007154 345 0.023
sexual reproduction GO:0019953 216 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.023
mitotic cell cycle GO:0000278 306 0.023
atp metabolic process GO:0046034 251 0.023
regulation of proteolysis GO:0030162 44 0.023
nucleus organization GO:0006997 62 0.022
protein processing GO:0016485 64 0.022
regulation of cell cycle process GO:0010564 150 0.022
methylation GO:0032259 101 0.021
sexual sporulation GO:0034293 113 0.021
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 11 0.021
negative regulation of cell cycle g2 m phase transition GO:1902750 5 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.020
nuclear transport GO:0051169 165 0.020
purine ribonucleoside catabolic process GO:0046130 330 0.020
negative regulation of mitotic metaphase anaphase transition GO:0045841 23 0.020
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.020
regulation of protein processing GO:0070613 34 0.019
mitotic sister chromatid separation GO:0051306 26 0.019
dna biosynthetic process GO:0071897 33 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.019
dna templated transcriptional preinitiation complex assembly GO:0070897 51 0.019
chromatin assembly or disassembly GO:0006333 60 0.019
purine ribonucleotide metabolic process GO:0009150 372 0.018
postreplication repair GO:0006301 24 0.018
dna templated transcription initiation GO:0006352 71 0.018
anatomical structure morphogenesis GO:0009653 160 0.018
organophosphate biosynthetic process GO:0090407 182 0.017
positive regulation of cellular component biogenesis GO:0044089 45 0.017
proteolysis GO:0006508 268 0.017
regulation of dna dependent dna replication GO:0090329 37 0.017
cellular developmental process GO:0048869 191 0.017
nucleoside monophosphate metabolic process GO:0009123 267 0.017
protein dna complex disassembly GO:0032986 20 0.017
dna replication okazaki fragment processing GO:0033567 7 0.017
single organism reproductive process GO:0044702 159 0.017
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 24 0.017
cell morphogenesis GO:0000902 30 0.016
nucleoside phosphate catabolic process GO:1901292 331 0.016
mitotic cell cycle checkpoint GO:0007093 56 0.016
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.016
macromolecular complex disassembly GO:0032984 80 0.016
microtubule polymerization GO:0046785 30 0.016
intracellular protein transport GO:0006886 319 0.016
positive regulation of dna templated transcription initiation GO:2000144 13 0.016
carboxylic acid metabolic process GO:0019752 338 0.016
negative regulation of chromosome organization GO:2001251 39 0.016
cell budding GO:0007114 48 0.015
organelle localization GO:0051640 128 0.015
negative regulation of nuclear division GO:0051784 62 0.015
response to uv GO:0009411 4 0.015
negative regulation of chromosome segregation GO:0051985 25 0.015
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.015
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 19 0.015
mitochondrion inheritance GO:0000001 21 0.015
positive regulation of cytoskeleton organization GO:0051495 39 0.014
gene conversion at mating type locus GO:0007534 11 0.014
response to endogenous stimulus GO:0009719 26 0.014
phosphorylation GO:0016310 291 0.013
nucleoside triphosphate catabolic process GO:0009143 329 0.013
transposition GO:0032196 20 0.013
proteasomal protein catabolic process GO:0010498 141 0.013
amino sugar metabolic process GO:0006040 20 0.013
regulation of metaphase anaphase transition of cell cycle GO:1902099 27 0.013
covalent chromatin modification GO:0016569 119 0.013
ribonucleoside monophosphate metabolic process GO:0009161 265 0.013
regulation of mitotic cell cycle GO:0007346 107 0.013
establishment or maintenance of cell polarity GO:0007163 96 0.013
positive regulation of cell communication GO:0010647 28 0.012
histone modification GO:0016570 119 0.012
cellular component morphogenesis GO:0032989 97 0.012
spindle assembly GO:0051225 9 0.012
carbohydrate derivative metabolic process GO:1901135 549 0.012
regulation of mitosis GO:0007088 65 0.012
peptidyl amino acid modification GO:0018193 116 0.012
double strand break repair via nonhomologous end joining GO:0006303 27 0.012
chromatin modification GO:0016568 200 0.012
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 23 0.012
negative regulation of mitotic sister chromatid separation GO:2000816 23 0.012
positive regulation of macromolecule metabolic process GO:0010604 394 0.012
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 35 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
cellular amine metabolic process GO:0044106 51 0.012
transposition rna mediated GO:0032197 17 0.011
mitotic spindle assembly checkpoint GO:0007094 23 0.011
cellular transition metal ion homeostasis GO:0046916 59 0.011
mitotic recombination GO:0006312 55 0.011
regulation of transposition rna mediated GO:0010525 15 0.011
response to abiotic stimulus GO:0009628 159 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.011
metaphase anaphase transition of cell cycle GO:0044784 28 0.011
multi organism reproductive process GO:0044703 216 0.011
negative regulation of dna recombination GO:0045910 13 0.011
protein phosphorylation GO:0006468 197 0.011
establishment of sister chromatid cohesion GO:0034085 17 0.011
negative regulation of meiotic cell cycle GO:0051447 24 0.011
protein localization to nucleus GO:0034504 74 0.011
reproductive process in single celled organism GO:0022413 145 0.011
negative regulation of mitosis GO:0045839 39 0.010
cytogamy GO:0000755 10 0.010
positive regulation of biosynthetic process GO:0009891 336 0.010
mitotic sister chromatid cohesion GO:0007064 38 0.010
nucleosome assembly GO:0006334 16 0.010
positive regulation of response to stimulus GO:0048584 37 0.010
regulation of catabolic process GO:0009894 199 0.010

RFA1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.025
disease of cellular proliferation DOID:14566 0 0.025
organ system cancer DOID:0050686 0 0.025