Saccharomyces cerevisiae

93 known processes

HIR1 (YBL008W)

Hir1p

HIR1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin assembly GO:0031497 35 0.985
protein dna complex assembly GO:0065004 105 0.951
dna packaging GO:0006323 55 0.913
dna conformation change GO:0071103 98 0.898
nucleosome organization GO:0034728 63 0.882
chromatin organization GO:0006325 242 0.853
chromatin assembly or disassembly GO:0006333 60 0.841
dna replication independent nucleosome organization GO:0034724 9 0.759
negative regulation of rna metabolic process GO:0051253 262 0.714
protein complex assembly GO:0006461 302 0.699
dna templated transcription elongation GO:0006354 91 0.683
protein dna complex subunit organization GO:0071824 153 0.662
negative regulation of biosynthetic process GO:0009890 312 0.662
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.615
protein complex biogenesis GO:0070271 314 0.575
transcription elongation from rna polymerase ii promoter GO:0006368 81 0.548
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.530
negative regulation of nucleic acid templated transcription GO:1903507 260 0.511
negative regulation of cellular biosynthetic process GO:0031327 312 0.506
negative regulation of transcription dna templated GO:0045892 258 0.501
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.452
regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0000083 27 0.444
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.442
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.419
negative regulation of rna biosynthetic process GO:1902679 260 0.418
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.403
nucleosome assembly GO:0006334 16 0.402
negative regulation of gene expression GO:0010629 312 0.376
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.324
cellular nitrogen compound catabolic process GO:0044270 494 0.290
mitotic cell cycle GO:0000278 306 0.283
regulation of organelle organization GO:0033043 243 0.280
cellular macromolecule catabolic process GO:0044265 363 0.280
cell cycle phase transition GO:0044770 144 0.275
negative regulation of macromolecule metabolic process GO:0010605 375 0.263
protein modification by small protein conjugation GO:0032446 144 0.260
nucleobase containing compound catabolic process GO:0034655 479 0.260
mrna metabolic process GO:0016071 269 0.249
positive regulation of macromolecule metabolic process GO:0010604 394 0.240
protein phosphorylation GO:0006468 197 0.239
mitotic cell cycle process GO:1903047 294 0.232
peptidyl amino acid modification GO:0018193 116 0.202
regulation of cellular protein metabolic process GO:0032268 232 0.201
regulation of protein metabolic process GO:0051246 237 0.197
cell cycle g1 s phase transition GO:0044843 64 0.196
peptidyl lysine modification GO:0018205 77 0.185
mitotic cell cycle phase transition GO:0044772 141 0.178
positive regulation of cellular biosynthetic process GO:0031328 336 0.176
regulation of cell cycle GO:0051726 195 0.172
chromatin modification GO:0016568 200 0.167
Fly
nucleoside phosphate metabolic process GO:0006753 458 0.157
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.154
carboxylic acid metabolic process GO:0019752 338 0.153
heterocycle catabolic process GO:0046700 494 0.152
negative regulation of cellular metabolic process GO:0031324 407 0.152
reproduction of a single celled organism GO:0032505 191 0.146
regulation of protein modification process GO:0031399 110 0.145
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.144
regulation of chromosome organization GO:0033044 66 0.138
homeostatic process GO:0042592 227 0.135
nucleobase containing small molecule metabolic process GO:0055086 491 0.133
regulation of biological quality GO:0065008 391 0.132
regulation of mitotic cell cycle GO:0007346 107 0.132
cellular protein catabolic process GO:0044257 213 0.128
positive regulation of transcription dna templated GO:0045893 286 0.119
covalent chromatin modification GO:0016569 119 0.118
g1 s transition of mitotic cell cycle GO:0000082 64 0.118
positive regulation of rna metabolic process GO:0051254 294 0.115
phosphorylation GO:0016310 291 0.114
organic cyclic compound catabolic process GO:1901361 499 0.114
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.114
macromolecule methylation GO:0043414 85 0.113
gene silencing GO:0016458 151 0.113
protein modification by small protein conjugation or removal GO:0070647 172 0.113
protein acetylation GO:0006473 59 0.110
cellular amino acid metabolic process GO:0006520 225 0.110
internal protein amino acid acetylation GO:0006475 52 0.109
aromatic compound catabolic process GO:0019439 491 0.108
regulation of cellular component organization GO:0051128 334 0.106
regulation of dna templated transcription elongation GO:0032784 44 0.105
protein catabolic process GO:0030163 221 0.104
transcription from rna polymerase i promoter GO:0006360 63 0.103
organelle fission GO:0048285 272 0.102
positive regulation of protein metabolic process GO:0051247 93 0.102
protein acylation GO:0043543 66 0.097
regulation of chromatin modification GO:1903308 23 0.095
positive regulation of nucleic acid templated transcription GO:1903508 286 0.094
mitotic cytokinesis GO:0000281 58 0.094
purine nucleotide metabolic process GO:0006163 376 0.093
positive regulation of biosynthetic process GO:0009891 336 0.093
cellular amine metabolic process GO:0044106 51 0.092
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.091
macromolecule catabolic process GO:0009057 383 0.089
carbohydrate metabolic process GO:0005975 252 0.089
cellular developmental process GO:0048869 191 0.089
Mouse
ribonucleoside monophosphate metabolic process GO:0009161 265 0.088
regulation of cellular ketone metabolic process GO:0010565 42 0.087
organophosphate metabolic process GO:0019637 597 0.087
dna recombination GO:0006310 172 0.086
anatomical structure development GO:0048856 160 0.085
Mouse Worm
positive regulation of cellular protein metabolic process GO:0032270 89 0.085
single organism developmental process GO:0044767 258 0.084
Mouse Worm
regulation of protein kinase activity GO:0045859 67 0.083
cell division GO:0051301 205 0.081
single organism reproductive process GO:0044702 159 0.080
Fly
histone acetylation GO:0016573 51 0.078
dna replication dependent nucleosome organization GO:0034723 5 0.076
nuclear division GO:0000280 263 0.076
ion homeostasis GO:0050801 118 0.075
dna replication independent nucleosome assembly GO:0006336 6 0.075
positive regulation of protein modification process GO:0031401 49 0.075
nucleotide metabolic process GO:0009117 453 0.075
chromatin silencing GO:0006342 147 0.073
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.072
anatomical structure morphogenesis GO:0009653 160 0.072
Mouse
negative regulation of gene expression epigenetic GO:0045814 147 0.072
nucleoside metabolic process GO:0009116 394 0.071
methylation GO:0032259 101 0.071
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.069
cellular response to chemical stimulus GO:0070887 315 0.068
single organism catabolic process GO:0044712 619 0.068
purine nucleoside triphosphate metabolic process GO:0009144 356 0.067
chromatin silencing at telomere GO:0006348 84 0.066
negative regulation of nuclear division GO:0051784 62 0.064
regulation of cell cycle process GO:0010564 150 0.060
cellular ketone metabolic process GO:0042180 63 0.060
regulation of histone modification GO:0031056 18 0.060
negative regulation of protein metabolic process GO:0051248 85 0.058
histone modification GO:0016570 119 0.056
chemical homeostasis GO:0048878 137 0.056
nuclear transcribed mrna catabolic process GO:0000956 89 0.056
developmental process involved in reproduction GO:0003006 159 0.054
negative regulation of cellular protein metabolic process GO:0032269 85 0.052
glucose metabolic process GO:0006006 65 0.052
positive regulation of gene expression GO:0010628 321 0.052
purine nucleoside triphosphate catabolic process GO:0009146 329 0.050
regulation of cell communication GO:0010646 124 0.050
cellular protein complex assembly GO:0043623 209 0.049
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.049
regulation of catabolic process GO:0009894 199 0.048
purine nucleoside monophosphate catabolic process GO:0009128 224 0.047
growth GO:0040007 157 0.047
proteolysis GO:0006508 268 0.046
ion transport GO:0006811 274 0.045
purine containing compound metabolic process GO:0072521 400 0.045
glycosyl compound metabolic process GO:1901657 398 0.045
sporulation GO:0043934 132 0.045
ribonucleoside metabolic process GO:0009119 389 0.045
nucleoside triphosphate catabolic process GO:0009143 329 0.044
organic acid metabolic process GO:0006082 352 0.044
oxoacid metabolic process GO:0043436 351 0.043
cellular carbohydrate metabolic process GO:0044262 135 0.043
positive regulation of rna biosynthetic process GO:1902680 286 0.043
negative regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0071930 7 0.043
meiotic cell cycle GO:0051321 272 0.043
regulation of cellular amine metabolic process GO:0033238 21 0.042
ribonucleoside monophosphate catabolic process GO:0009158 224 0.042
mrna catabolic process GO:0006402 93 0.041
anatomical structure homeostasis GO:0060249 74 0.041
ubiquitin dependent protein catabolic process GO:0006511 181 0.040
regulation of gene expression epigenetic GO:0040029 147 0.040
developmental process GO:0032502 261 0.039
Mouse Worm
cellular response to nutrient levels GO:0031669 144 0.039
cellular homeostasis GO:0019725 138 0.039
single organism carbohydrate metabolic process GO:0044723 237 0.039
cellular response to external stimulus GO:0071496 150 0.039
nucleoside phosphate catabolic process GO:1901292 331 0.038
ribonucleotide metabolic process GO:0009259 377 0.038
cellular chemical homeostasis GO:0055082 123 0.038
reproductive process in single celled organism GO:0022413 145 0.038
response to chemical GO:0042221 390 0.038
signaling GO:0023052 208 0.037
regulation of cellular component biogenesis GO:0044087 112 0.036
signal transduction GO:0007165 208 0.035
cellular response to extracellular stimulus GO:0031668 150 0.035
alcohol metabolic process GO:0006066 112 0.035
purine nucleoside monophosphate metabolic process GO:0009126 262 0.035
trna processing GO:0008033 101 0.034
organonitrogen compound catabolic process GO:1901565 404 0.034
rna catabolic process GO:0006401 118 0.033
cell communication GO:0007154 345 0.033
modification dependent macromolecule catabolic process GO:0043632 203 0.033
cellular cation homeostasis GO:0030003 100 0.032
meiotic cell cycle process GO:1903046 229 0.032
ribonucleoside catabolic process GO:0042454 332 0.032
sexual sporulation GO:0034293 113 0.032
purine ribonucleotide metabolic process GO:0009150 372 0.031
modification dependent protein catabolic process GO:0019941 181 0.030
ribonucleotide catabolic process GO:0009261 327 0.030
protein ubiquitination GO:0016567 118 0.030
nucleotide catabolic process GO:0009166 330 0.030
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.030
positive regulation of transcription from rna polymerase ii promoter in response to ethanol GO:0061410 3 0.030
trna metabolic process GO:0006399 151 0.030
carbohydrate derivative metabolic process GO:1901135 549 0.030
negative regulation of organelle organization GO:0010639 103 0.029
regulation of cell division GO:0051302 113 0.029
cation homeostasis GO:0055080 105 0.029
carbon catabolite regulation of transcription GO:0045990 39 0.029
nucleobase containing compound transport GO:0015931 124 0.029
cytokinetic process GO:0032506 78 0.028
response to oxidative stress GO:0006979 99 0.028
reproductive process GO:0022414 248 0.028
Fly
regulation of phosphorus metabolic process GO:0051174 230 0.028
oxidation reduction process GO:0055114 353 0.028
protein methylation GO:0006479 48 0.027
ribonucleoside triphosphate catabolic process GO:0009203 327 0.027
negative regulation of chromosome organization GO:2001251 39 0.027
rna localization GO:0006403 112 0.027
glycosyl compound catabolic process GO:1901658 335 0.027
cellular response to starvation GO:0009267 90 0.026
regulation of proteolysis GO:0030162 44 0.026
purine ribonucleoside catabolic process GO:0046130 330 0.026
response to nutrient levels GO:0031667 150 0.026
purine nucleoside metabolic process GO:0042278 380 0.026
negative regulation of cell division GO:0051782 66 0.026
translation GO:0006412 230 0.026
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.026
proteasomal protein catabolic process GO:0010498 141 0.026
regulation of nuclear division GO:0051783 103 0.026
response to organic cyclic compound GO:0014070 1 0.026
response to external stimulus GO:0009605 158 0.026
regulation of cellular catabolic process GO:0031329 195 0.026
regulation of response to stimulus GO:0048583 157 0.026
regulation of histone acetylation GO:0035065 7 0.026
regulation of cell cycle phase transition GO:1901987 70 0.025
cellular response to oxidative stress GO:0034599 94 0.025
ribose phosphate metabolic process GO:0019693 384 0.025
regulation of phosphate metabolic process GO:0019220 230 0.025
regulation of proteasomal protein catabolic process GO:0061136 34 0.025
protein processing GO:0016485 64 0.024
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 38 0.024
nucleoside triphosphate metabolic process GO:0009141 364 0.024
positive regulation of cellular catabolic process GO:0031331 128 0.024
response to extracellular stimulus GO:0009991 156 0.024
cellular lipid metabolic process GO:0044255 229 0.024
single organism signaling GO:0044700 208 0.024
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 27 0.023
regulation of localization GO:0032879 127 0.023
telomere organization GO:0032200 75 0.023
regulation of chromatin organization GO:1902275 23 0.023
rna 3 end processing GO:0031123 88 0.023
dna repair GO:0006281 236 0.023
organophosphate catabolic process GO:0046434 338 0.023
regulation of protein acetylation GO:1901983 7 0.023
dna templated transcription termination GO:0006353 42 0.023
posttranscriptional regulation of gene expression GO:0010608 115 0.023
positive regulation of cell communication GO:0010647 28 0.022
purine nucleotide catabolic process GO:0006195 328 0.022
cytoskeleton dependent cytokinesis GO:0061640 65 0.022
purine ribonucleoside metabolic process GO:0046128 380 0.022
positive regulation of dna templated transcription elongation GO:0032786 42 0.022
trna modification GO:0006400 75 0.022
metal ion homeostasis GO:0055065 79 0.022
response to osmotic stress GO:0006970 83 0.022
nucleoside catabolic process GO:0009164 335 0.022
sporulation resulting in formation of a cellular spore GO:0030435 129 0.022
telomere maintenance GO:0000723 74 0.022
atp metabolic process GO:0046034 251 0.022
regulation of transcription by chromatin organization GO:0034401 19 0.021
negative regulation of cellular component organization GO:0051129 109 0.021
purine nucleoside catabolic process GO:0006152 330 0.021
cytokinesis GO:0000910 92 0.021
positive regulation of chromatin modification GO:1903310 13 0.020
positive regulation of cell cycle process GO:0090068 31 0.020
protein autophosphorylation GO:0046777 15 0.020
cellular ion homeostasis GO:0006873 112 0.020
maintenance of location GO:0051235 66 0.020
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 40 0.020
regulation of signaling GO:0023051 119 0.020
cellular metal ion homeostasis GO:0006875 78 0.020
negative regulation of cellular protein catabolic process GO:1903363 27 0.020
dna replication dependent nucleosome assembly GO:0006335 5 0.020
positive regulation of catabolic process GO:0009896 135 0.019
amine metabolic process GO:0009308 51 0.019
negative regulation of protein processing GO:0010955 33 0.018
multi organism reproductive process GO:0044703 216 0.018
Fly
positive regulation of histone modification GO:0031058 12 0.018
regulation of protein phosphorylation GO:0001932 75 0.018
filamentous growth GO:0030447 124 0.018
cell fate commitment GO:0045165 32 0.018
regulation of mitotic cell cycle phase transition GO:1901990 68 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.018
meiotic nuclear division GO:0007126 163 0.018
regulation of translation GO:0006417 89 0.017
nucleoside monophosphate catabolic process GO:0009125 224 0.017
polysaccharide biosynthetic process GO:0000271 39 0.017
negative regulation of cell cycle process GO:0010948 86 0.017
pseudohyphal growth GO:0007124 75 0.017
negative regulation of phosphorus metabolic process GO:0010563 49 0.017
maintenance of protein location in cell GO:0032507 50 0.017
maintenance of location in cell GO:0051651 58 0.017
positive regulation of cellular amine metabolic process GO:0033240 10 0.017
nucleoside monophosphate metabolic process GO:0009123 267 0.017
regulation of generation of precursor metabolites and energy GO:0043467 23 0.016
glycerolipid metabolic process GO:0046486 108 0.016
regulation of cellular carbohydrate metabolic process GO:0010675 41 0.016
anatomical structure formation involved in morphogenesis GO:0048646 136 0.016
negative regulation of protein maturation GO:1903318 33 0.016
atp catabolic process GO:0006200 224 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 7 0.015
atp dependent chromatin remodeling GO:0043044 36 0.015
Fly
regulation of chromatin silencing GO:0031935 39 0.015
cell budding GO:0007114 48 0.015
purine ribonucleotide catabolic process GO:0009154 327 0.015
positive regulation of transcription from rna polymerase ii promoter by oleic acid GO:0061429 4 0.015
regulation of peptidyl lysine acetylation GO:2000756 7 0.015
small molecule catabolic process GO:0044282 88 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.015
negative regulation of cell cycle phase transition GO:1901988 59 0.015
sexual reproduction GO:0019953 216 0.015
Fly
regulation of chromosome segregation GO:0051983 44 0.015
regulation of carbohydrate metabolic process GO:0006109 43 0.014
rna splicing GO:0008380 131 0.014
positive regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0036091 3 0.014
mitotic sister chromatid separation GO:0051306 26 0.014
cellular response to heat GO:0034605 53 0.014
regulation of cellular response to stress GO:0080135 50 0.014
regulation of transferase activity GO:0051338 83 0.014
chromatin silencing at rdna GO:0000183 32 0.014
organelle assembly GO:0070925 118 0.014
Fly
positive regulation of lipid catabolic process GO:0050996 4 0.014
regulation of cellular protein catabolic process GO:1903362 36 0.014
rrna transcription GO:0009303 31 0.014
death GO:0016265 30 0.014
filamentous growth of a population of unicellular organisms GO:0044182 109 0.014
regulation of growth GO:0040008 50 0.014
steroid biosynthetic process GO:0006694 35 0.014
chromatin silencing at silent mating type cassette GO:0030466 53 0.014
vesicle mediated transport GO:0016192 335 0.014
organic acid catabolic process GO:0016054 71 0.014
monocarboxylic acid metabolic process GO:0032787 122 0.013
positive regulation of cellular response to drug GO:2001040 3 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 36 0.013
regulation of response to drug GO:2001023 3 0.013
polysaccharide metabolic process GO:0005976 60 0.013
mitotic cytokinetic process GO:1902410 45 0.013
multi organism process GO:0051704 233 0.013
Fly
regulation of dna templated transcription in response to stress GO:0043620 51 0.013
maintenance of dna repeat elements GO:0043570 20 0.013
dna catabolic process GO:0006308 42 0.013
cell aging GO:0007569 70 0.013
positive regulation of phosphate metabolic process GO:0045937 147 0.013
regulation of lipid catabolic process GO:0050994 4 0.013
regulation of dna metabolic process GO:0051052 100 0.013
response to drug GO:0042493 41 0.013
spindle assembly checkpoint GO:0071173 23 0.013
regulation of protein complex assembly GO:0043254 77 0.013
regulation of molecular function GO:0065009 320 0.013
response to organic substance GO:0010033 182 0.013
regulation of metal ion transport GO:0010959 2 0.013
regulation of meiosis GO:0040020 42 0.013
positive regulation of mitotic cell cycle GO:0045931 16 0.013
lipid catabolic process GO:0016042 33 0.013
macromolecular complex disassembly GO:0032984 80 0.012
cellular component disassembly GO:0022411 86 0.012
regulation of replicative cell aging GO:1900062 4 0.012
budding cell bud growth GO:0007117 29 0.012
regulation of phosphorylation GO:0042325 86 0.012
cellular response to dna damage stimulus GO:0006974 287 0.012
cellular amide metabolic process GO:0043603 59 0.012
alcohol biosynthetic process GO:0046165 75 0.012
mitotic recombination GO:0006312 55 0.012
lipid metabolic process GO:0006629 269 0.012
regulation of signal transduction GO:0009966 114 0.012
response to temperature stimulus GO:0009266 74 0.012
negative regulation of phosphate metabolic process GO:0045936 49 0.012
maintenance of protein location GO:0045185 53 0.012
carbohydrate derivative catabolic process GO:1901136 339 0.012
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 33 0.012
organophosphate biosynthetic process GO:0090407 182 0.012
telomere maintenance via recombination GO:0000722 32 0.012
regulation of sodium ion transport GO:0002028 1 0.012
cellular response to nutrient GO:0031670 50 0.011
response to calcium ion GO:0051592 1 0.011
regulation of kinase activity GO:0043549 71 0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 35 0.011
purine containing compound catabolic process GO:0072523 332 0.011
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 51 0.011
cell differentiation GO:0030154 161 0.011
Mouse
positive regulation of molecular function GO:0044093 185 0.011
dna geometric change GO:0032392 43 0.011
stress activated protein kinase signaling cascade GO:0031098 4 0.011
cation transport GO:0006812 166 0.011
negative regulation of cell communication GO:0010648 33 0.011
mitochondrion organization GO:0007005 261 0.011
monosaccharide metabolic process GO:0005996 83 0.011
rna transport GO:0050658 92 0.011
ribonucleoside triphosphate metabolic process GO:0009199 356 0.011
negative regulation of signal transduction GO:0009968 30 0.010
positive regulation of fatty acid beta oxidation GO:0032000 3 0.010
nucleic acid transport GO:0050657 94 0.010
organic hydroxy compound metabolic process GO:1901615 125 0.010
rna modification GO:0009451 99 0.010
small molecule biosynthetic process GO:0044283 258 0.010
mrna processing GO:0006397 185 0.010
chromatin remodeling GO:0006338 80 0.010
Fly
cellular lipid catabolic process GO:0044242 33 0.010
response to blue light GO:0009637 2 0.010
cellular response to calcium ion GO:0071277 1 0.010
single organism membrane organization GO:0044802 275 0.010
glycerophospholipid metabolic process GO:0006650 98 0.010

HIR1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012