Saccharomyces cerevisiae

101 known processes

MSH6 (YDR097C)

Msh6p

(Aliases: PMS3)

MSH6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 236 0.998
cellular response to dna damage stimulus GO:0006974 287 0.980
double strand break repair GO:0006302 105 0.877
mismatch repair GO:0006298 14 0.657
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.559
telomere maintenance GO:0000723 74 0.534
meiosis i GO:0007127 92 0.489
anatomical structure homeostasis GO:0060249 74 0.472
telomere organization GO:0032200 75 0.460
postreplication repair GO:0006301 24 0.437
lagging strand elongation GO:0006273 10 0.424
homeostatic process GO:0042592 227 0.388
maintenance of dna repeat elements GO:0043570 20 0.341
Worm
nucleotide excision repair GO:0006289 50 0.336
mitotic recombination GO:0006312 55 0.319
meiotic cell cycle GO:0051321 272 0.299
telomere maintenance via recombination GO:0000722 32 0.298
heterocycle catabolic process GO:0046700 494 0.271
double strand break repair via homologous recombination GO:0000724 54 0.214
aromatic compound catabolic process GO:0019439 491 0.213
dna dependent dna replication GO:0006261 115 0.191
organic cyclic compound catabolic process GO:1901361 499 0.189
telomere maintenance via telomerase GO:0007004 21 0.186
dna strand elongation GO:0022616 29 0.170
hexose metabolic process GO:0019318 78 0.162
cellular macromolecule catabolic process GO:0044265 363 0.156
dna strand elongation involved in dna replication GO:0006271 26 0.155
organophosphate metabolic process GO:0019637 597 0.149
cellular nitrogen compound catabolic process GO:0044270 494 0.148
recombinational repair GO:0000725 64 0.142
meiotic nuclear division GO:0007126 163 0.139
signaling GO:0023052 208 0.137
Mouse
regulation of molecular function GO:0065009 320 0.136
Human
reciprocal meiotic recombination GO:0007131 54 0.135
meiotic mismatch repair GO:0000710 9 0.134
nucleobase containing compound catabolic process GO:0034655 479 0.131
nuclear division GO:0000280 263 0.130
mating type switching GO:0007533 28 0.119
non recombinational repair GO:0000726 33 0.116
base excision repair GO:0006284 14 0.115
meiotic cell cycle process GO:1903046 229 0.113
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.108
Human Mouse
regulation of catalytic activity GO:0050790 307 0.105
Human
negative regulation of cellular metabolic process GO:0031324 407 0.103
Human Mouse
reproduction of a single celled organism GO:0032505 191 0.102
organelle fission GO:0048285 272 0.100
dna recombination GO:0006310 172 0.096
Human Mouse
rna dependent dna replication GO:0006278 25 0.092
regulation of dna metabolic process GO:0051052 100 0.079
Human Mouse
macromolecule catabolic process GO:0009057 383 0.077
cellular protein complex assembly GO:0043623 209 0.077
ribonucleoside monophosphate metabolic process GO:0009161 265 0.074
telomere maintenance via telomere lengthening GO:0010833 22 0.068
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.065
dna catabolic process GO:0006308 42 0.062
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.062
Human Mouse
dna biosynthetic process GO:0071897 33 0.058
regulation of biological quality GO:0065008 391 0.058
cell fate commitment GO:0045165 32 0.058
gene conversion at mating type locus GO:0007534 11 0.056
regulation of response to stimulus GO:0048583 157 0.053
nucleoside phosphate metabolic process GO:0006753 458 0.052
mating type determination GO:0007531 32 0.052
single organism catabolic process GO:0044712 619 0.051
dna unwinding involved in dna replication GO:0006268 13 0.051
sex determination GO:0007530 32 0.048
purine nucleoside triphosphate catabolic process GO:0009146 329 0.048
single organism developmental process GO:0044767 258 0.047
Mouse
negative regulation of macromolecule metabolic process GO:0010605 375 0.046
Human Mouse
organonitrogen compound catabolic process GO:1901565 404 0.045
negative regulation of dna metabolic process GO:0051053 36 0.045
Human Mouse
nucleotide metabolic process GO:0009117 453 0.045
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.044
purine nucleoside monophosphate metabolic process GO:0009126 262 0.043
developmental process involved in reproduction GO:0003006 159 0.042
regulation of cell communication GO:0010646 124 0.041
positive regulation of molecular function GO:0044093 185 0.041
Human
developmental process GO:0032502 261 0.040
Mouse
regulation of dna recombination GO:0000018 24 0.039
Human Mouse
nucleobase containing small molecule metabolic process GO:0055086 491 0.038
regulation of phosphate metabolic process GO:0019220 230 0.038
response to organic substance GO:0010033 182 0.038
protein modification by small protein conjugation GO:0032446 144 0.037
cellular homeostasis GO:0019725 138 0.035
regulation of signaling GO:0023051 119 0.035
regulation of hydrolase activity GO:0051336 133 0.034
Human
nucleoside monophosphate metabolic process GO:0009123 267 0.033
nucleoside catabolic process GO:0009164 335 0.032
regulation of protein metabolic process GO:0051246 237 0.032
reproductive process GO:0022414 248 0.032
ribonucleoside monophosphate catabolic process GO:0009158 224 0.031
regulation of dna dependent dna replication GO:0090329 37 0.031
atp metabolic process GO:0046034 251 0.030
positive regulation of macromolecule metabolic process GO:0010604 394 0.030
dna duplex unwinding GO:0032508 42 0.030
monosaccharide metabolic process GO:0005996 83 0.029
cell differentiation GO:0030154 161 0.029
regulation of signal transduction GO:0009966 114 0.028
translesion synthesis GO:0019985 16 0.028
dna catabolic process endonucleolytic GO:0000737 31 0.028
positive regulation of hydrolase activity GO:0051345 112 0.028
Human
rna catabolic process GO:0006401 118 0.028
phosphorylation GO:0016310 291 0.027
gene conversion GO:0035822 14 0.027
intracellular signal transduction GO:0035556 112 0.027
Mouse
rna phosphodiester bond hydrolysis GO:0090501 112 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.026
response to chemical GO:0042221 390 0.026
cell communication GO:0007154 345 0.025
Mouse
mitotic cell cycle phase transition GO:0044772 141 0.025
positive regulation of rna metabolic process GO:0051254 294 0.024
ion homeostasis GO:0050801 118 0.024
negative regulation of biosynthetic process GO:0009890 312 0.024
protein complex assembly GO:0006461 302 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.023
purine containing compound catabolic process GO:0072523 332 0.023
regulation of cellular response to stress GO:0080135 50 0.023
positive regulation of catalytic activity GO:0043085 178 0.023
Human
response to uv GO:0009411 4 0.022
Mouse
signal transduction GO:0007165 208 0.022
Mouse
organophosphate biosynthetic process GO:0090407 182 0.022
cellular chemical homeostasis GO:0055082 123 0.021
purine nucleotide metabolic process GO:0006163 376 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.021
positive regulation of cellular biosynthetic process GO:0031328 336 0.021
cellular ion homeostasis GO:0006873 112 0.020
protein complex biogenesis GO:0070271 314 0.020
carbohydrate derivative catabolic process GO:1901136 339 0.020
cell budding GO:0007114 48 0.018
regulation of cellular protein metabolic process GO:0032268 232 0.017
cellular response to chemical stimulus GO:0070887 315 0.017
purine nucleoside monophosphate catabolic process GO:0009128 224 0.017
double strand break repair via nonhomologous end joining GO:0006303 27 0.017
dna packaging GO:0006323 55 0.017
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 79 0.017
atp catabolic process GO:0006200 224 0.017
regulation of phosphorus metabolic process GO:0051174 230 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.016
ribonucleoside triphosphate metabolic process GO:0009199 356 0.016
regulation of helicase activity GO:0051095 3 0.016
Human
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.015
dna integrity checkpoint GO:0031570 41 0.015
ribonucleotide catabolic process GO:0009261 327 0.015
single organism signaling GO:0044700 208 0.015
Mouse
dna replication okazaki fragment processing GO:0033567 7 0.015
chemical homeostasis GO:0048878 137 0.015
nucleoside triphosphate catabolic process GO:0009143 329 0.014
cellular developmental process GO:0048869 191 0.014
regulation of dna replication GO:0006275 51 0.014
reproductive process in single celled organism GO:0022413 145 0.014
nucleoside monophosphate biosynthetic process GO:0009124 33 0.014
chromatin modification GO:0016568 200 0.014
cellular amine metabolic process GO:0044106 51 0.014
regulation of translation GO:0006417 89 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.014
negative regulation of cellular biosynthetic process GO:0031327 312 0.014
establishment of protein localization GO:0045184 367 0.013
ribonucleoside metabolic process GO:0009119 389 0.013
purine nucleotide catabolic process GO:0006195 328 0.013
membrane organization GO:0061024 276 0.013
purine ribonucleotide metabolic process GO:0009150 372 0.013
organophosphate catabolic process GO:0046434 338 0.013
dna replication removal of rna primer GO:0043137 5 0.013
cell cycle phase transition GO:0044770 144 0.012
nucleotide catabolic process GO:0009166 330 0.012
cell cycle checkpoint GO:0000075 82 0.012
negative regulation of catalytic activity GO:0043086 60 0.012
protein ubiquitination GO:0016567 118 0.012
purine ribonucleotide catabolic process GO:0009154 327 0.012
purine nucleoside metabolic process GO:0042278 380 0.012
chromatin organization GO:0006325 242 0.011
transition metal ion homeostasis GO:0055076 59 0.011
response to abiotic stimulus GO:0009628 159 0.011
Mouse
cell division GO:0051301 205 0.011
dna geometric change GO:0032392 43 0.011
dna damage checkpoint GO:0000077 29 0.011
reciprocal dna recombination GO:0035825 54 0.011
organic hydroxy compound metabolic process GO:1901615 125 0.011
ribonucleoside catabolic process GO:0042454 332 0.011
protein localization to organelle GO:0033365 337 0.011
regulation of intracellular signal transduction GO:1902531 78 0.011
aging GO:0007568 71 0.011
Mouse
amine metabolic process GO:0009308 51 0.010
cell cycle g1 s phase transition GO:0044843 64 0.010
dna replication GO:0006260 147 0.010
positive regulation of programmed cell death GO:0043068 3 0.010

MSH6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.013
Human
disease of cellular proliferation DOID:14566 0 0.013
Human
organ system cancer DOID:0050686 0 0.013
Human