Saccharomyces cerevisiae

42 known processes

SIZ1 (YDR409W)

Siz1p

(Aliases: ULL1)

SIZ1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation GO:0032446 144 0.640
protein modification by small protein conjugation or removal GO:0070647 172 0.618
dna repair GO:0006281 236 0.498
protein ubiquitination GO:0016567 118 0.395
cellular response to dna damage stimulus GO:0006974 287 0.395
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.355
Human
negative regulation of rna biosynthetic process GO:1902679 260 0.258
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.231
negative regulation of gene expression GO:0010629 312 0.207
Human Yeast
negative regulation of macromolecule metabolic process GO:0010605 375 0.204
negative regulation of biosynthetic process GO:0009890 312 0.202
Human
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.200
Human
positive regulation of rna metabolic process GO:0051254 294 0.194
Rat
negative regulation of rna metabolic process GO:0051253 262 0.188
Human
positive regulation of nucleic acid templated transcription GO:1903508 286 0.186
Rat
double strand break repair GO:0006302 105 0.162
negative regulation of response to stimulus GO:0048585 40 0.152
Human
reproductive process GO:0022414 248 0.138
Rat
response to chemical GO:0042221 390 0.136
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.134
Human
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.133
Human
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.130
Rat
positive regulation of macromolecule metabolic process GO:0010604 394 0.127
Human Rat
regulation of biological quality GO:0065008 391 0.127
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.123
Rat
macromolecule catabolic process GO:0009057 383 0.114
signaling GO:0023052 208 0.106
Human Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.104
Rat
single organism signaling GO:0044700 208 0.104
Human Rat
positive regulation of transcription dna templated GO:0045893 286 0.103
Rat
microtubule cytoskeleton organization GO:0000226 109 0.101
positive regulation of protein modification by small protein conjugation or removal GO:1903322 12 0.096
Human
metal ion transport GO:0030001 75 0.093
Rat
negative regulation of signal transduction GO:0009968 30 0.092
Human
negative regulation of cellular metabolic process GO:0031324 407 0.092
postreplication repair GO:0006301 24 0.091
carbohydrate derivative metabolic process GO:1901135 549 0.088
positive regulation of gene expression GO:0010628 321 0.084
Rat
negative regulation of transcription dna templated GO:0045892 258 0.079
Human
mrna processing GO:0006397 185 0.077
ubiquitin dependent protein catabolic process GO:0006511 181 0.076
purine nucleoside catabolic process GO:0006152 330 0.075
regulation of cellular protein metabolic process GO:0032268 232 0.071
double strand break repair via homologous recombination GO:0000724 54 0.071
single organism catabolic process GO:0044712 619 0.071
dna conformation change GO:0071103 98 0.068
mrna metabolic process GO:0016071 269 0.068
regulation of signaling GO:0023051 119 0.067
Human Rat
reproduction of a single celled organism GO:0032505 191 0.065
regulation of cell communication GO:0010646 124 0.064
Human Rat
ion transport GO:0006811 274 0.064
Rat
regulation of response to stimulus GO:0048583 157 0.064
Human Rat
carbohydrate metabolic process GO:0005975 252 0.061
proteolysis GO:0006508 268 0.060
regulation of signal transduction GO:0009966 114 0.060
Human Rat
nucleotide metabolic process GO:0009117 453 0.060
purine nucleoside metabolic process GO:0042278 380 0.059
atp metabolic process GO:0046034 251 0.059
modification dependent macromolecule catabolic process GO:0043632 203 0.059
microtubule based process GO:0007017 117 0.058
signal transduction GO:0007165 208 0.058
Human Rat
negative regulation of cell communication GO:0010648 33 0.055
Human
purine ribonucleoside metabolic process GO:0046128 380 0.055
proteasomal protein catabolic process GO:0010498 141 0.055
nuclear division GO:0000280 263 0.054
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.054
nucleoside triphosphate metabolic process GO:0009141 364 0.054
anatomical structure morphogenesis GO:0009653 160 0.054
Rat
histone modification GO:0016570 119 0.052
mitotic cell cycle GO:0000278 306 0.052
organophosphate metabolic process GO:0019637 597 0.052
response to organic cyclic compound GO:0014070 1 0.051
Rat
cellular macromolecule catabolic process GO:0044265 363 0.051
cellular protein catabolic process GO:0044257 213 0.051
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.050
cell communication GO:0007154 345 0.050
Human Rat
regulation of response to stress GO:0080134 57 0.050
organic anion transport GO:0015711 114 0.050
regulation of protein modification process GO:0031399 110 0.049
purine ribonucleoside catabolic process GO:0046130 330 0.049
modification dependent protein catabolic process GO:0019941 181 0.048
cellular nitrogen compound catabolic process GO:0044270 494 0.048
rna splicing GO:0008380 131 0.048
ribonucleotide catabolic process GO:0009261 327 0.047
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.047
negative regulation of signaling GO:0023057 30 0.046
Human
anatomical structure development GO:0048856 160 0.045
Rat
purine containing compound catabolic process GO:0072523 332 0.045
regulation of protein metabolic process GO:0051246 237 0.042
cellular developmental process GO:0048869 191 0.042
Rat
glycosyl compound metabolic process GO:1901657 398 0.042
purine containing compound metabolic process GO:0072521 400 0.041
regulation of cell cycle phase transition GO:1901987 70 0.041
mitotic cell cycle process GO:1903047 294 0.040
regulation of protein modification by small protein conjugation or removal GO:1903320 29 0.039
meiotic nuclear division GO:0007126 163 0.039
carbohydrate derivative catabolic process GO:1901136 339 0.039
ribonucleoside monophosphate metabolic process GO:0009161 265 0.038
positive regulation of rna biosynthetic process GO:1902680 286 0.038
Rat
developmental process GO:0032502 261 0.038
Rat
carboxylic acid metabolic process GO:0019752 338 0.038
nucleoside phosphate catabolic process GO:1901292 331 0.037
single organism reproductive process GO:0044702 159 0.037
Rat
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.037
positive regulation of biosynthetic process GO:0009891 336 0.037
Rat
protein complex assembly GO:0006461 302 0.037
negative regulation of nucleic acid templated transcription GO:1903507 260 0.037
Human
heterocycle catabolic process GO:0046700 494 0.036
nucleobase containing compound catabolic process GO:0034655 479 0.036
reproductive process in single celled organism GO:0022413 145 0.036
non recombinational repair GO:0000726 33 0.035
glycosyl compound catabolic process GO:1901658 335 0.035
cell differentiation GO:0030154 161 0.035
Rat
protein sumoylation GO:0016925 17 0.034
ribonucleoprotein complex assembly GO:0022618 143 0.034
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.034
ribonucleoside catabolic process GO:0042454 332 0.033
ribonucleoside triphosphate catabolic process GO:0009203 327 0.033
regulation of dna repair GO:0006282 14 0.033
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 51 0.032
transmembrane transport GO:0055085 349 0.032
Rat
regulation of cellular component biogenesis GO:0044087 112 0.032
lipid metabolic process GO:0006629 269 0.032
nucleoside monophosphate metabolic process GO:0009123 267 0.032
homeostatic process GO:0042592 227 0.032
purine nucleotide catabolic process GO:0006195 328 0.032
sexual reproduction GO:0019953 216 0.031
Rat
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.031
cytoskeleton organization GO:0007010 230 0.031
g2 m transition of mitotic cell cycle GO:0000086 38 0.030
cellular lipid metabolic process GO:0044255 229 0.030
organonitrogen compound catabolic process GO:1901565 404 0.030
purine nucleoside triphosphate metabolic process GO:0009144 356 0.030
nucleoside phosphate metabolic process GO:0006753 458 0.029
regulation of cellular catabolic process GO:0031329 195 0.029
organic cyclic compound catabolic process GO:1901361 499 0.029
nucleoside metabolic process GO:0009116 394 0.029
positive regulation of protein metabolic process GO:0051247 93 0.029
Human
chromatin organization GO:0006325 242 0.029
covalent chromatin modification GO:0016569 119 0.028
organophosphate ester transport GO:0015748 45 0.028
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.028
negative regulation of protein metabolic process GO:0051248 85 0.028
reciprocal meiotic recombination GO:0007131 54 0.028
aromatic compound catabolic process GO:0019439 491 0.028
cellular response to chemical stimulus GO:0070887 315 0.027
recombinational repair GO:0000725 64 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.027
positive regulation of catabolic process GO:0009896 135 0.027
negative regulation of cellular biosynthetic process GO:0031327 312 0.027
Human
purine nucleoside triphosphate catabolic process GO:0009146 329 0.027
nucleoside catabolic process GO:0009164 335 0.027
nucleoside triphosphate catabolic process GO:0009143 329 0.027
ribonucleoside triphosphate metabolic process GO:0009199 356 0.026
nucleobase containing small molecule metabolic process GO:0055086 491 0.026
rna 3 end processing GO:0031123 88 0.026
developmental process involved in reproduction GO:0003006 159 0.026
response to uv GO:0009411 4 0.025
organic acid metabolic process GO:0006082 352 0.024
protein deacylation GO:0035601 27 0.024
cell cycle g2 m phase transition GO:0044839 39 0.024
regulation of dna templated transcription in response to stress GO:0043620 51 0.024
double strand break repair via synthesis dependent strand annealing GO:0045003 12 0.024
double strand break repair via nonhomologous end joining GO:0006303 27 0.024
membrane organization GO:0061024 276 0.024
response to osmotic stress GO:0006970 83 0.023
ribonucleoside metabolic process GO:0009119 389 0.023
telomere organization GO:0032200 75 0.023
alcohol metabolic process GO:0006066 112 0.022
alcohol biosynthetic process GO:0046165 75 0.022
protein catabolic process GO:0030163 221 0.022
regulation of cellular response to stress GO:0080135 50 0.022
purine nucleoside monophosphate catabolic process GO:0009128 224 0.022
single organism nuclear import GO:1902593 56 0.022
positive regulation of catalytic activity GO:0043085 178 0.022
small molecule biosynthetic process GO:0044283 258 0.021
purine nucleoside monophosphate metabolic process GO:0009126 262 0.021
lipid biosynthetic process GO:0008610 170 0.021
regulation of catabolic process GO:0009894 199 0.021
multi organism process GO:0051704 233 0.021
Rat
protein dna complex subunit organization GO:0071824 153 0.020
phospholipid biosynthetic process GO:0008654 89 0.020
multi organism reproductive process GO:0044703 216 0.019
Rat
lipid translocation GO:0034204 13 0.019
organelle fission GO:0048285 272 0.019
sphingolipid biosynthetic process GO:0030148 29 0.018
cell wall organization GO:0071555 146 0.018
dna dependent dna replication GO:0006261 115 0.018
regulation of response to dna damage stimulus GO:2001020 17 0.018
rna splicing via transesterification reactions GO:0000375 118 0.018
response to abiotic stimulus GO:0009628 159 0.018
regulation of cellular component size GO:0032535 50 0.018
meiotic cell cycle GO:0051321 272 0.018
regulation of metal ion transport GO:0010959 2 0.018
nucleotide excision repair GO:0006289 50 0.018
regulation of cell cycle GO:0051726 195 0.017
chromatin assembly or disassembly GO:0006333 60 0.017
atp catabolic process GO:0006200 224 0.017
nucleoside monophosphate catabolic process GO:0009125 224 0.017
dna recombinase assembly GO:0000730 9 0.017
monocarboxylic acid metabolic process GO:0032787 122 0.017
regulation of protein complex assembly GO:0043254 77 0.017
anatomical structure homeostasis GO:0060249 74 0.017
single organism developmental process GO:0044767 258 0.017
Rat
endomembrane system organization GO:0010256 74 0.017
organelle localization GO:0051640 128 0.017
cellular response to abiotic stimulus GO:0071214 62 0.017
cation homeostasis GO:0055080 105 0.017
nucleotide catabolic process GO:0009166 330 0.017
cell fate commitment GO:0045165 32 0.017
rrna metabolic process GO:0016072 244 0.017
purine nucleotide metabolic process GO:0006163 376 0.017
regulation of dna metabolic process GO:0051052 100 0.017
sex determination GO:0007530 32 0.017
phospholipid transport GO:0015914 23 0.017
cell surface receptor signaling pathway GO:0007166 38 0.016
macromolecule methylation GO:0043414 85 0.016
ribonucleoside monophosphate catabolic process GO:0009158 224 0.016
regulation of anatomical structure size GO:0090066 50 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.016
mitochondrial genome maintenance GO:0000002 40 0.016
translation GO:0006412 230 0.016
regulation of cellular component organization GO:0051128 334 0.016
Rat
invasive growth in response to glucose limitation GO:0001403 61 0.016
dna packaging GO:0006323 55 0.015
cellular component disassembly GO:0022411 86 0.015
dna geometric change GO:0032392 43 0.015
protein complex biogenesis GO:0070271 314 0.015
cell cycle phase transition GO:0044770 144 0.015
cation transport GO:0006812 166 0.015
Rat
nuclear import GO:0051170 57 0.015
dna replication GO:0006260 147 0.015
single organism membrane organization GO:0044802 275 0.015
ribonucleoprotein complex subunit organization GO:0071826 152 0.015
posttranscriptional regulation of gene expression GO:0010608 115 0.015
purine ribonucleotide metabolic process GO:0009150 372 0.014
organelle inheritance GO:0048308 51 0.014
peroxisome organization GO:0007031 68 0.014
vesicle mediated transport GO:0016192 335 0.014
purine ribonucleotide catabolic process GO:0009154 327 0.014
positive regulation of apoptotic process GO:0043065 3 0.014
conjugation with cellular fusion GO:0000747 106 0.014
phosphorylation GO:0016310 291 0.014
chromatin modification GO:0016568 200 0.014
cellular response to hypoxia GO:0071456 4 0.014
protein localization to nucleus GO:0034504 74 0.014
regulation of hydrolase activity GO:0051336 133 0.014
ribonucleotide metabolic process GO:0009259 377 0.014
positive regulation of sodium ion transport GO:0010765 1 0.013
regulation of organelle organization GO:0033043 243 0.013
translesion synthesis GO:0019985 16 0.013
organophosphate catabolic process GO:0046434 338 0.013
macromolecule deacylation GO:0098732 27 0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 109 0.013
positive regulation of cellular protein metabolic process GO:0032270 89 0.013
Human
ion transmembrane transport GO:0034220 200 0.013
Rat
peptidyl amino acid modification GO:0018193 116 0.013
rna localization GO:0006403 112 0.013
single organism carbohydrate metabolic process GO:0044723 237 0.013
positive regulation of intracellular transport GO:0032388 4 0.013
glycerolipid metabolic process GO:0046486 108 0.013
positive regulation of growth GO:0045927 19 0.013
positive regulation of cellular catabolic process GO:0031331 128 0.012
lipid transport GO:0006869 58 0.012
protein maturation GO:0051604 76 0.012
mismatch repair GO:0006298 14 0.012
negative regulation of organelle organization GO:0010639 103 0.012
organelle assembly GO:0070925 118 0.012
organic hydroxy compound metabolic process GO:1901615 125 0.012
divalent inorganic cation transport GO:0072511 26 0.012
transcription elongation from rna polymerase ii promoter GO:0006368 81 0.012
single organism carbohydrate catabolic process GO:0044724 73 0.012
growth GO:0040007 157 0.012
divalent inorganic cation homeostasis GO:0072507 21 0.012
cellular cation homeostasis GO:0030003 100 0.012
mating type switching GO:0007533 28 0.012
negative regulation of cell cycle process GO:0010948 86 0.012
rna catabolic process GO:0006401 118 0.012
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 30 0.012
sporulation resulting in formation of a cellular spore GO:0030435 129 0.012
positive regulation of programmed cell death GO:0043068 3 0.012
regulation of cellular ketone metabolic process GO:0010565 42 0.012
establishment or maintenance of cell polarity GO:0007163 96 0.011
negative regulation of gene silencing GO:0060969 27 0.011
Yeast
positive regulation of cytoplasmic transport GO:1903651 4 0.011
response to hypoxia GO:0001666 4 0.011
regulation of sodium ion transport GO:0002028 1 0.011
positive regulation of protein modification process GO:0031401 49 0.011
Human
cell division GO:0051301 205 0.011
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.011
regulation of catalytic activity GO:0050790 307 0.011
cellular homeostasis GO:0019725 138 0.011
telomere maintenance GO:0000723 74 0.011
reciprocal dna recombination GO:0035825 54 0.011
nucleocytoplasmic transport GO:0006913 163 0.011
sister chromatid segregation GO:0000819 93 0.011
negative regulation of gene expression epigenetic GO:0045814 147 0.011
oxoacid metabolic process GO:0043436 351 0.011
protein modification by small protein removal GO:0070646 29 0.011
regulation of transport GO:0051049 85 0.011
small molecule catabolic process GO:0044282 88 0.011
positive regulation of organelle organization GO:0010638 85 0.011
mrna splicing via spliceosome GO:0000398 108 0.011
cellular transition metal ion homeostasis GO:0046916 59 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.010
positive regulation of nucleoside metabolic process GO:0045979 97 0.010
macromolecular complex disassembly GO:0032984 80 0.010
misfolded or incompletely synthesized protein catabolic process GO:0006515 21 0.010
ncrna processing GO:0034470 330 0.010
cellular response to oxidative stress GO:0034599 94 0.010
cellular biogenic amine metabolic process GO:0006576 37 0.010
positive regulation of cell growth GO:0030307 7 0.010
oxidation reduction process GO:0055114 353 0.010
chromosome organization involved in meiosis GO:0070192 32 0.010
nuclear transcribed mrna poly a tail shortening GO:0000289 14 0.010
regulation of cellular amino acid metabolic process GO:0006521 16 0.010
regulation of localization GO:0032879 127 0.010

SIZ1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
disease of anatomical entity DOID:7 0 0.010