Saccharomyces cerevisiae

109 known processes

PKH1 (YDR490C)

Pkh1p

PKH1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of macromolecule metabolic process GO:0010604 394 0.440
Human
vesicle mediated transport GO:0016192 335 0.335
mitotic cell cycle process GO:1903047 294 0.252
cell wall organization or biogenesis GO:0071554 190 0.250
translational initiation GO:0006413 56 0.214
regulation of mitotic cell cycle GO:0007346 107 0.204
lipid metabolic process GO:0006629 269 0.182
positive regulation of cellular component organization GO:0051130 116 0.170
Human
cellular ion homeostasis GO:0006873 112 0.166
Human
nitrogen compound transport GO:0071705 212 0.160
negative regulation of cellular biosynthetic process GO:0031327 312 0.159
negative regulation of cellular metabolic process GO:0031324 407 0.155
Human
positive regulation of gene expression GO:0010628 321 0.155
external encapsulating structure organization GO:0045229 146 0.152
regulation of biological quality GO:0065008 391 0.149
Human Fly
positive regulation of rna biosynthetic process GO:1902680 286 0.138
positive regulation of biosynthetic process GO:0009891 336 0.137
cellular lipid metabolic process GO:0044255 229 0.124
negative regulation of biosynthetic process GO:0009890 312 0.122
nuclear transport GO:0051169 165 0.121
negative regulation of rna metabolic process GO:0051253 262 0.118
mrna metabolic process GO:0016071 269 0.104
positive regulation of rna metabolic process GO:0051254 294 0.101
regulation of anatomical structure size GO:0090066 50 0.098
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.097
positive regulation of transcription dna templated GO:0045893 286 0.095
nuclear export GO:0051168 124 0.094
positive regulation of cellular protein metabolic process GO:0032270 89 0.092
Human
protein depolymerization GO:0051261 21 0.091
organophosphate catabolic process GO:0046434 338 0.090
cell growth GO:0016049 89 0.090
Fly
organophosphate metabolic process GO:0019637 597 0.087
endocytosis GO:0006897 90 0.087
positive regulation of nucleic acid templated transcription GO:1903508 286 0.086
regulation of cellular component biogenesis GO:0044087 112 0.085
positive regulation of kinase activity GO:0033674 24 0.084
Human
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.083
nucleocytoplasmic transport GO:0006913 163 0.081
cellular chemical homeostasis GO:0055082 123 0.081
Human
aromatic compound catabolic process GO:0019439 491 0.076
establishment or maintenance of cell polarity GO:0007163 96 0.075
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.074
ribonucleotide catabolic process GO:0009261 327 0.073
actin filament based process GO:0030029 104 0.072
regulation of cellular component size GO:0032535 50 0.072
Fly
translation GO:0006412 230 0.071
cellular component movement GO:0006928 20 0.070
Human Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.068
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 51 0.067
regulation of cellular component organization GO:0051128 334 0.065
Human Fly
regulation of cellular protein metabolic process GO:0032268 232 0.065
Human
protein localization to membrane GO:0072657 102 0.065
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.064
organonitrogen compound catabolic process GO:1901565 404 0.064
mitotic cell cycle GO:0000278 306 0.063
purine nucleoside triphosphate catabolic process GO:0009146 329 0.062
ribonucleoside monophosphate metabolic process GO:0009161 265 0.062
nucleoside catabolic process GO:0009164 335 0.062
regulation of response to stress GO:0080134 57 0.061
Mouse
regulation of dna metabolic process GO:0051052 100 0.061
cellular protein complex disassembly GO:0043624 42 0.061
regulation of cellular catabolic process GO:0031329 195 0.061
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.061
cellular nitrogen compound catabolic process GO:0044270 494 0.060
regulation of cell cycle GO:0051726 195 0.060
carbohydrate metabolic process GO:0005975 252 0.060
nucleobase containing compound catabolic process GO:0034655 479 0.059
positive regulation of protein kinase activity GO:0045860 22 0.059
Human
regulation of phosphorus metabolic process GO:0051174 230 0.058
Human
regulation of transferase activity GO:0051338 83 0.057
Human
fungal type cell wall organization GO:0031505 145 0.056
filamentous growth of a population of unicellular organisms GO:0044182 109 0.056
negative regulation of organelle organization GO:0010639 103 0.055
cellular response to extracellular stimulus GO:0031668 150 0.054
cellular response to dna damage stimulus GO:0006974 287 0.053
Fly
regulation of kinase activity GO:0043549 71 0.053
Human
negative regulation of gene expression GO:0010629 312 0.052
mitochondrial translation GO:0032543 52 0.052
membrane organization GO:0061024 276 0.052
Human
response to chemical GO:0042221 390 0.051
Human Worm
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.051
ion homeostasis GO:0050801 118 0.050
Human
nucleoside phosphate catabolic process GO:1901292 331 0.050
response to extracellular stimulus GO:0009991 156 0.049
vacuolar transport GO:0007034 145 0.049
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.048
homeostatic process GO:0042592 227 0.048
Human
dna replication GO:0006260 147 0.048
growth GO:0040007 157 0.048
Fly
cellular response to chemical stimulus GO:0070887 315 0.047
Human
response to nutrient GO:0007584 52 0.047
nucleoside triphosphate metabolic process GO:0009141 364 0.047
anatomical structure homeostasis GO:0060249 74 0.047
negative regulation of macromolecule metabolic process GO:0010605 375 0.046
Human
regulation of protein phosphorylation GO:0001932 75 0.046
Human
purine containing compound catabolic process GO:0072523 332 0.046
ribonucleoprotein complex assembly GO:0022618 143 0.045
positive regulation of cellular biosynthetic process GO:0031328 336 0.045
response to abiotic stimulus GO:0009628 159 0.045
Mouse
telomere maintenance GO:0000723 74 0.045
protein transport GO:0015031 345 0.043
positive regulation of protein metabolic process GO:0051247 93 0.043
Human
activation of protein kinase activity GO:0032147 9 0.043
Human
regulation of catabolic process GO:0009894 199 0.043
organic cyclic compound catabolic process GO:1901361 499 0.043
cell wall organization GO:0071555 146 0.042
multi organism process GO:0051704 233 0.042
heterocycle catabolic process GO:0046700 494 0.042
negative regulation of rna biosynthetic process GO:1902679 260 0.041
nucleobase containing small molecule metabolic process GO:0055086 491 0.040
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.040
cellular response to nutrient GO:0031670 50 0.039
response to external stimulus GO:0009605 158 0.039
Worm
rna catabolic process GO:0006401 118 0.038
positive regulation of catalytic activity GO:0043085 178 0.038
Human
regulation of protein metabolic process GO:0051246 237 0.038
Human
ribonucleoprotein complex subunit organization GO:0071826 152 0.038
maintenance of location GO:0051235 66 0.038
ribonucleoside monophosphate catabolic process GO:0009158 224 0.038
positive regulation of hydrolase activity GO:0051345 112 0.038
Human
signaling GO:0023052 208 0.038
regulation of protein complex assembly GO:0043254 77 0.037
carboxylic acid biosynthetic process GO:0046394 152 0.037
ribonucleoside triphosphate metabolic process GO:0009199 356 0.036
carbohydrate derivative metabolic process GO:1901135 549 0.036
regulation of lipid metabolic process GO:0019216 45 0.035
regulation of protein kinase activity GO:0045859 67 0.035
Human
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.035
positive regulation of protein phosphorylation GO:0001934 28 0.035
Human
response to glucose GO:0009749 13 0.035
protein localization to nucleus GO:0034504 74 0.035
regulation of cell size GO:0008361 30 0.034
Fly
purine ribonucleoside catabolic process GO:0046130 330 0.034
negative regulation of transcription dna templated GO:0045892 258 0.034
organelle localization GO:0051640 128 0.034
Mouse
positive regulation of mitotic cell cycle GO:0045931 16 0.033
fungal type cell wall organization or biogenesis GO:0071852 169 0.032
cellular homeostasis GO:0019725 138 0.032
Human
cell communication GO:0007154 345 0.032
nucleotide catabolic process GO:0009166 330 0.032
positive regulation of intracellular transport GO:0032388 4 0.032
Human
nuclear transcribed mrna catabolic process GO:0000956 89 0.032
cellular carbohydrate catabolic process GO:0044275 33 0.032
macromolecular complex disassembly GO:0032984 80 0.031
positive regulation of filamentous growth of a population of unicellular organisms GO:1900430 18 0.031
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.031
regulation of catalytic activity GO:0050790 307 0.031
Human
atp metabolic process GO:0046034 251 0.031
negative regulation of protein kinase activity GO:0006469 23 0.031
Human
regulation of cell growth GO:0001558 29 0.030
Fly
negative regulation of protein modification process GO:0031400 37 0.030
Human
protein complex disassembly GO:0043241 70 0.030
glycosyl compound metabolic process GO:1901657 398 0.030
purine ribonucleoside metabolic process GO:0046128 380 0.030
single organism carbohydrate metabolic process GO:0044723 237 0.029
cellular response to abiotic stimulus GO:0071214 62 0.029
regulation of growth of unicellular organism as a thread of attached cells GO:0070784 31 0.029
pseudohyphal growth GO:0007124 75 0.029
regulation of protein localization GO:0032880 62 0.029
Human
negative regulation of nucleic acid templated transcription GO:1903507 260 0.029
protein folding GO:0006457 94 0.028
negative regulation of protein phosphorylation GO:0001933 24 0.028
Human
purine nucleoside monophosphate metabolic process GO:0009126 262 0.027
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.027
negative regulation of cellular component organization GO:0051129 109 0.027
ribonucleoside catabolic process GO:0042454 332 0.027
cytokinesis GO:0000910 92 0.027
positive regulation of nucleotide catabolic process GO:0030813 97 0.027
protein import into nucleus GO:0006606 55 0.027
cell cycle phase transition GO:0044770 144 0.026
actin cytoskeleton organization GO:0030036 100 0.026
ribonucleotide metabolic process GO:0009259 377 0.026
establishment of protein localization to membrane GO:0090150 99 0.026
Human
response to nutrient levels GO:0031667 150 0.026
regulation of transport GO:0051049 85 0.026
Human Mouse
mrna 3 end processing GO:0031124 54 0.026
vesicle organization GO:0016050 68 0.025
positive regulation of organelle organization GO:0010638 85 0.025
regulation of protein modification process GO:0031399 110 0.025
Human
nucleoside metabolic process GO:0009116 394 0.025
protein complex biogenesis GO:0070271 314 0.025
positive regulation of molecular function GO:0044093 185 0.025
Human
regulation of metal ion transport GO:0010959 2 0.025
Human
nucleoside monophosphate catabolic process GO:0009125 224 0.025
monosaccharide metabolic process GO:0005996 83 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.024
cellular response to external stimulus GO:0071496 150 0.024
disaccharide catabolic process GO:0046352 17 0.024
endosomal transport GO:0016197 86 0.024
invasive filamentous growth GO:0036267 65 0.024
reproduction of a single celled organism GO:0032505 191 0.024
purine ribonucleotide metabolic process GO:0009150 372 0.024
rna transport GO:0050658 92 0.023
single organism catabolic process GO:0044712 619 0.023
glycerolipid metabolic process GO:0046486 108 0.023
lipid biosynthetic process GO:0008610 170 0.023
cytoskeleton dependent cytokinesis GO:0061640 65 0.023
purine nucleoside metabolic process GO:0042278 380 0.023
positive regulation of cellular catabolic process GO:0031331 128 0.022
regulation of localization GO:0032879 127 0.022
Human Mouse
cellular carbohydrate metabolic process GO:0044262 135 0.022
negative regulation of response to stimulus GO:0048585 40 0.022
Human Mouse
response to topologically incorrect protein GO:0035966 38 0.022
intracellular signal transduction GO:0035556 112 0.022
endomembrane system organization GO:0010256 74 0.022
Human
regulation of organelle organization GO:0033043 243 0.022
nucleoside phosphate metabolic process GO:0006753 458 0.022
atp catabolic process GO:0006200 224 0.022
regulation of cell communication GO:0010646 124 0.021
Human Mouse
cellular protein complex assembly GO:0043623 209 0.021
mitotic cytokinesis GO:0000281 58 0.021
nucleoside monophosphate metabolic process GO:0009123 267 0.021
cellular cation homeostasis GO:0030003 100 0.021
Human
positive regulation of catabolic process GO:0009896 135 0.021
carbohydrate transport GO:0008643 33 0.021
establishment of rna localization GO:0051236 92 0.021
mitochondrion organization GO:0007005 261 0.020
conjugation GO:0000746 107 0.020
macromolecule catabolic process GO:0009057 383 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.020
regulation of molecular function GO:0065009 320 0.020
Human
regulation of signal transduction GO:0009966 114 0.020
Human Mouse
mitotic sister chromatid segregation GO:0000070 85 0.020
reproductive process GO:0022414 248 0.020
negative regulation of phosphorus metabolic process GO:0010563 49 0.019
Human
establishment of organelle localization GO:0051656 96 0.019
nucleobase containing compound transport GO:0015931 124 0.019
membrane lipid biosynthetic process GO:0046467 54 0.019
regulation of cellular response to drug GO:2001038 3 0.019
secretion by cell GO:0032940 50 0.019
Mouse
transmembrane transport GO:0055085 349 0.019
cellular polysaccharide metabolic process GO:0044264 55 0.019
mitotic cell cycle phase transition GO:0044772 141 0.019
metal ion homeostasis GO:0055065 79 0.018
Human
monocarboxylic acid metabolic process GO:0032787 122 0.018
regulation of intracellular transport GO:0032386 26 0.018
Human Mouse
negative regulation of invasive growth in response to glucose limitation by negative regulation of transcription from rna polymerase ii promoter GO:1900460 3 0.018
establishment of protein localization GO:0045184 367 0.018
Human
rna 3 end processing GO:0031123 88 0.018
conjugation with cellular fusion GO:0000747 106 0.018
protein phosphorylation GO:0006468 197 0.017
intracellular protein transport GO:0006886 319 0.017
positive regulation of phosphorylation GO:0042327 33 0.017
Human
sphingolipid biosynthetic process GO:0030148 29 0.017
glucan metabolic process GO:0044042 44 0.017
negative regulation of cytoskeleton organization GO:0051494 24 0.017
carbon catabolite regulation of transcription GO:0045990 39 0.017
positive regulation of cytoplasmic transport GO:1903651 4 0.017
Human
regulation of chromosome organization GO:0033044 66 0.017
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 34 0.017
lipid oxidation GO:0034440 13 0.017
single organism cellular localization GO:1902580 375 0.017
Human Mouse
filamentous growth GO:0030447 124 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
late endosome to vacuole transport via multivesicular body sorting pathway GO:0032511 26 0.017
telomere maintenance via recombination GO:0000722 32 0.017
positive regulation of protein modification process GO:0031401 49 0.016
Human
cell division GO:0051301 205 0.016
rna localization GO:0006403 112 0.016
ras protein signal transduction GO:0007265 29 0.016
regulation of dna templated transcription in response to stress GO:0043620 51 0.016
mating type determination GO:0007531 32 0.016
dephosphorylation GO:0016311 127 0.016
cellular component disassembly GO:0022411 86 0.016
single organism membrane organization GO:0044802 275 0.016
Human
glycosyl compound catabolic process GO:1901658 335 0.016
response to oxygen containing compound GO:1901700 61 0.016
Human
regulation of establishment of protein localization GO:0070201 17 0.016
Human
positive regulation of homeostatic process GO:0032846 2 0.016
Human
protein targeting GO:0006605 272 0.016
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 44 0.016
positive regulation of lipid catabolic process GO:0050996 4 0.016
cellular response to nutrient levels GO:0031669 144 0.015
response to organic cyclic compound GO:0014070 1 0.015
organic anion transport GO:0015711 114 0.015
single organism carbohydrate catabolic process GO:0044724 73 0.015
organic acid biosynthetic process GO:0016053 152 0.015
regulation of filamentous growth GO:0010570 38 0.015
negative regulation of catalytic activity GO:0043086 60 0.015
Human
regulation of cellular localization GO:0060341 50 0.015
Human Mouse
regulation of dna replication GO:0006275 51 0.015
regulation of vesicle mediated transport GO:0060627 39 0.015
Mouse
microtubule polymerization or depolymerization GO:0031109 36 0.015
mitotic recombination GO:0006312 55 0.015
reproductive process in single celled organism GO:0022413 145 0.015
posttranscriptional regulation of gene expression GO:0010608 115 0.014
negative regulation of homeostatic process GO:0032845 7 0.014
Human
detection of hexose stimulus GO:0009732 3 0.014
developmental process involved in reproduction GO:0003006 159 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.014
gene silencing GO:0016458 151 0.014
carbohydrate derivative catabolic process GO:1901136 339 0.014
phosphatidylinositol metabolic process GO:0046488 62 0.014
regulation of actin cytoskeleton organization GO:0032956 31 0.014
protein localization to organelle GO:0033365 337 0.014
ribonucleoside metabolic process GO:0009119 389 0.014
establishment of protein localization to organelle GO:0072594 278 0.014
oxoacid metabolic process GO:0043436 351 0.014
ribose phosphate metabolic process GO:0019693 384 0.014
regulation of response to drug GO:2001023 3 0.014
response to carbohydrate GO:0009743 14 0.013
chromosome segregation GO:0007059 159 0.013
phosphorylation GO:0016310 291 0.013
regulation of gene expression epigenetic GO:0040029 147 0.013
regulation of protein polymerization GO:0032271 33 0.013
endosome transport via multivesicular body sorting pathway GO:0032509 27 0.013
cellular response to nitrogen compound GO:1901699 14 0.013
Human
positive regulation of fatty acid oxidation GO:0046321 3 0.013
regulation of transcription by glucose GO:0046015 13 0.013
mrna processing GO:0006397 185 0.013
detection of stimulus GO:0051606 4 0.013
plasma membrane organization GO:0007009 21 0.013
Human
carbohydrate derivative biosynthetic process GO:1901137 181 0.013
iron sulfur cluster assembly GO:0016226 22 0.013
glycoprotein biosynthetic process GO:0009101 61 0.013
protein complex assembly GO:0006461 302 0.013
single organism developmental process GO:0044767 258 0.013
Mouse Worm Fly
negative regulation of phosphate metabolic process GO:0045936 49 0.013
Human
regulation of lipid biosynthetic process GO:0046890 32 0.012
eisosome assembly GO:0070941 8 0.012
signal transduction GO:0007165 208 0.012
detection of carbohydrate stimulus GO:0009730 3 0.012
nucleic acid transport GO:0050657 94 0.012
rrna processing GO:0006364 227 0.012
positive regulation of secretion GO:0051047 2 0.012
cellular response to starvation GO:0009267 90 0.012
negative regulation of transferase activity GO:0051348 31 0.012
Human
metallo sulfur cluster assembly GO:0031163 22 0.012
negative regulation of intracellular signal transduction GO:1902532 27 0.012
regulation of purine nucleotide metabolic process GO:1900542 109 0.012
cell cycle g1 s phase transition GO:0044843 64 0.012
endoplasmic reticulum organization GO:0007029 30 0.012
chemical homeostasis GO:0048878 137 0.012
Human
regulation of gtp catabolic process GO:0033124 84 0.011
inclusion body assembly GO:0070841 1 0.011
cellular ketone metabolic process GO:0042180 63 0.011
mrna catabolic process GO:0006402 93 0.011
regulation of carbohydrate metabolic process GO:0006109 43 0.011
positive regulation of secretion by cell GO:1903532 2 0.011
cellular amino acid biosynthetic process GO:0008652 118 0.011
carbon catabolite activation of transcription GO:0045991 26 0.011
positive regulation of cell death GO:0010942 3 0.011
positive regulation of cellular response to drug GO:2001040 3 0.011
response to uv GO:0009411 4 0.011
microtubule based process GO:0007017 117 0.011
exit from mitosis GO:0010458 37 0.011
cell wall macromolecule metabolic process GO:0044036 27 0.011
purine nucleoside monophosphate catabolic process GO:0009128 224 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
Human
regulation of dna recombination GO:0000018 24 0.011
disaccharide metabolic process GO:0005984 25 0.011
rna export from nucleus GO:0006405 88 0.011
signal transduction by phosphorylation GO:0023014 31 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.011
phospholipid metabolic process GO:0006644 125 0.010
glucose catabolic process GO:0006007 17 0.010
protein targeting to nucleus GO:0044744 57 0.010
cellular response to oxygen containing compound GO:1901701 43 0.010
Human
negative regulation of cell communication GO:0010648 33 0.010
Human Mouse
monosaccharide catabolic process GO:0046365 28 0.010
glycosylation GO:0070085 66 0.010
carbohydrate catabolic process GO:0016052 77 0.010
positive regulation of fatty acid beta oxidation GO:0032000 3 0.010
organic hydroxy compound transport GO:0015850 41 0.010
regulation of cellular ketone metabolic process GO:0010565 42 0.010
microtubule cytoskeleton organization GO:0000226 109 0.010
regulation of growth GO:0040008 50 0.010
Fly
divalent metal ion transport GO:0070838 17 0.010
Human
regulation of response to stimulus GO:0048583 157 0.010
Human Mouse Worm
response to oxidative stress GO:0006979 99 0.010
cell wall assembly GO:0070726 54 0.010
dna repair GO:0006281 236 0.010
purine nucleotide metabolic process GO:0006163 376 0.010
nucleotide metabolic process GO:0009117 453 0.010
cellular response to organonitrogen compound GO:0071417 14 0.010
Human

PKH1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org