Saccharomyces cerevisiae

38 known processes

RPN11 (YFR004W)

Rpn11p

(Aliases: MPR1)

RPN11 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent protein catabolic process GO:0019941 181 0.980
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.970
modification dependent macromolecule catabolic process GO:0043632 203 0.956
proteolysis GO:0006508 268 0.948
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.886
protein catabolic process GO:0030163 221 0.848
ubiquitin dependent protein catabolic process GO:0006511 181 0.825
proteasomal protein catabolic process GO:0010498 141 0.800
cellular macromolecule catabolic process GO:0044265 363 0.776
cellular protein catabolic process GO:0044257 213 0.747
mitotic cell cycle process GO:1903047 294 0.507
mitotic cell cycle GO:0000278 306 0.352
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 30 0.338
Fly
mitotic nuclear division GO:0007067 131 0.335
macromolecule catabolic process GO:0009057 383 0.333
nuclear division GO:0000280 263 0.270
organelle fission GO:0048285 272 0.251
single organism catabolic process GO:0044712 619 0.234
intracellular protein transport GO:0006886 319 0.211
protein targeting GO:0006605 272 0.207
regulation of protein catabolic process GO:0042176 40 0.198
Human Fly
chromosome segregation GO:0007059 159 0.191
negative regulation of macromolecule metabolic process GO:0010605 375 0.172
sexual reproduction GO:0019953 216 0.167
cellular response to dna damage stimulus GO:0006974 287 0.161
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.161
developmental process GO:0032502 261 0.144
Worm
single organism developmental process GO:0044767 258 0.134
Worm
cell differentiation GO:0030154 161 0.124
cellular developmental process GO:0048869 191 0.123
protein complex biogenesis GO:0070271 314 0.121
negative regulation of cellular metabolic process GO:0031324 407 0.114
protein transport GO:0015031 345 0.104
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.101
negative regulation of gene expression GO:0010629 312 0.099
positive regulation of macromolecule metabolic process GO:0010604 394 0.095
Human Fly
regulation of mitosis GO:0007088 65 0.090
negative regulation of biosynthetic process GO:0009890 312 0.088
regulation of mitotic cell cycle GO:0007346 107 0.086
cellular protein complex assembly GO:0043623 209 0.083
carbohydrate derivative metabolic process GO:1901135 549 0.082
protein complex assembly GO:0006461 302 0.076
multi organism reproductive process GO:0044703 216 0.070
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 35 0.068
regulation of cellular component organization GO:0051128 334 0.065
positive regulation of gene expression GO:0010628 321 0.063
regulation of molecular function GO:0065009 320 0.063
Human
protein localization to organelle GO:0033365 337 0.060
protein localization to nucleus GO:0034504 74 0.059
er associated ubiquitin dependent protein catabolic process GO:0030433 46 0.058
anatomical structure development GO:0048856 160 0.055
Worm
cell cycle phase transition GO:0044770 144 0.054
regulation of protein metabolic process GO:0051246 237 0.053
Human Fly
regulation of cell cycle process GO:0010564 150 0.052
negative regulation of cellular biosynthetic process GO:0031327 312 0.048
reproductive process GO:0022414 248 0.048
regulation of cell cycle GO:0051726 195 0.047
positive regulation of nucleic acid templated transcription GO:1903508 286 0.047
single organism signaling GO:0044700 208 0.046
protein dna complex subunit organization GO:0071824 153 0.046
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.045
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.044
single organism cellular localization GO:1902580 375 0.042
negative regulation of rna biosynthetic process GO:1902679 260 0.040
positive regulation of rna biosynthetic process GO:1902680 286 0.040
negative regulation of nucleic acid templated transcription GO:1903507 260 0.040
regulation of signaling GO:0023051 119 0.038
anatomical structure formation involved in morphogenesis GO:0048646 136 0.038
multi organism process GO:0051704 233 0.038
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.038
nucleocytoplasmic transport GO:0006913 163 0.037
regulation of cellular component biogenesis GO:0044087 112 0.035
microtubule based process GO:0007017 117 0.035
single organism membrane organization GO:0044802 275 0.034
cytoskeleton organization GO:0007010 230 0.034
regulation of chromosome organization GO:0033044 66 0.033
cellular nitrogen compound catabolic process GO:0044270 494 0.033
mitotic cell cycle phase transition GO:0044772 141 0.033
sporulation resulting in formation of a cellular spore GO:0030435 129 0.033
organophosphate metabolic process GO:0019637 597 0.031
positive regulation of cellular biosynthetic process GO:0031328 336 0.030
mitotic sister chromatid segregation GO:0000070 85 0.030
positive regulation of biosynthetic process GO:0009891 336 0.029
positive regulation of transcription dna templated GO:0045893 286 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.029
regulation of localization GO:0032879 127 0.028
nucleobase containing compound catabolic process GO:0034655 479 0.028
regulation of nuclear division GO:0051783 103 0.028
nucleobase containing small molecule metabolic process GO:0055086 491 0.028
establishment of protein localization to organelle GO:0072594 278 0.028
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.027
organonitrogen compound catabolic process GO:1901565 404 0.027
cell communication GO:0007154 345 0.027
aromatic compound catabolic process GO:0019439 491 0.027
positive regulation of rna metabolic process GO:0051254 294 0.026
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.026
regulation of cellular catabolic process GO:0031329 195 0.026
Human Fly
protein modification by small protein conjugation or removal GO:0070647 172 0.025
negative regulation of protein metabolic process GO:0051248 85 0.025
meiotic cell cycle process GO:1903046 229 0.025
regulation of response to stimulus GO:0048583 157 0.024
negative regulation of transcription dna templated GO:0045892 258 0.024
vesicle mediated transport GO:0016192 335 0.024
negative regulation of rna metabolic process GO:0051253 262 0.023
regulation of cell division GO:0051302 113 0.022
spindle organization GO:0007051 37 0.022
rrna metabolic process GO:0016072 244 0.022
regulation of biological quality GO:0065008 391 0.022
response to organic substance GO:0010033 182 0.022
positive regulation of molecular function GO:0044093 185 0.021
Human
regulation of gene expression epigenetic GO:0040029 147 0.021
sister chromatid segregation GO:0000819 93 0.020
regulation of phosphorus metabolic process GO:0051174 230 0.020
regulation of organelle organization GO:0033043 243 0.020
positive regulation of catabolic process GO:0009896 135 0.020
Fly
nucleotide metabolic process GO:0009117 453 0.019
reproduction of a single celled organism GO:0032505 191 0.019
anatomical structure morphogenesis GO:0009653 160 0.018
protein complex localization GO:0031503 32 0.018
positive regulation of cellular component organization GO:0051130 116 0.018
conjugation with cellular fusion GO:0000747 106 0.018
microtubule cytoskeleton organization GO:0000226 109 0.017
regulation of phosphate metabolic process GO:0019220 230 0.017
heterocycle catabolic process GO:0046700 494 0.017
regulation of catabolic process GO:0009894 199 0.017
Human Fly
regulation of protein complex assembly GO:0043254 77 0.017
nucleoside phosphate metabolic process GO:0006753 458 0.016
glycosyl compound catabolic process GO:1901658 335 0.016
ascospore wall assembly GO:0030476 52 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.015
gene silencing GO:0016458 151 0.015
sporulation GO:0043934 132 0.015
ascospore wall biogenesis GO:0070591 52 0.015
nuclear transport GO:0051169 165 0.015
positive regulation of catalytic activity GO:0043085 178 0.015
Human
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 36 0.015
Human Fly
mitotic spindle organization GO:0007052 30 0.014
rrna catabolic process GO:0016075 31 0.014
negative regulation of protein maturation GO:1903318 33 0.014
proteasomal ubiquitin independent protein catabolic process GO:0010499 14 0.014
reproductive process in single celled organism GO:0022413 145 0.014
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.014
signaling GO:0023052 208 0.014
purine nucleoside catabolic process GO:0006152 330 0.014
membrane organization GO:0061024 276 0.014
single organism reproductive process GO:0044702 159 0.014
regulation of proteasomal protein catabolic process GO:0061136 34 0.013
Human Fly
ascospore formation GO:0030437 107 0.013
response to chemical GO:0042221 390 0.013
nucleoside phosphate catabolic process GO:1901292 331 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
purine ribonucleoside catabolic process GO:0046130 330 0.013
purine containing compound catabolic process GO:0072523 332 0.012
sexual sporulation GO:0034293 113 0.012
negative regulation of proteasomal protein catabolic process GO:1901799 25 0.012
purine nucleotide catabolic process GO:0006195 328 0.012
establishment of protein localization GO:0045184 367 0.012
purine ribonucleotide catabolic process GO:0009154 327 0.012
meiotic cell cycle GO:0051321 272 0.012
nucleoside triphosphate catabolic process GO:0009143 329 0.012
regulation of dna metabolic process GO:0051052 100 0.012
ncrna catabolic process GO:0034661 33 0.012
multi organism cellular process GO:0044764 120 0.012
ribonucleotide catabolic process GO:0009261 327 0.011
regulation of cell communication GO:0010646 124 0.011
protein processing GO:0016485 64 0.011
regulation of protein maturation GO:1903317 34 0.011
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 27 0.011
ribonucleoside triphosphate catabolic process GO:0009203 327 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.011
negative regulation of proteolysis GO:0045861 33 0.011
positive regulation of phosphorus metabolic process GO:0010562 147 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.011
purine nucleoside triphosphate catabolic process GO:0009146 329 0.011
conjugation GO:0000746 107 0.011
carbohydrate derivative catabolic process GO:1901136 339 0.011
nucleotide catabolic process GO:0009166 330 0.011
regulation of cell cycle phase transition GO:1901987 70 0.011
dna templated transcription elongation GO:0006354 91 0.010
protein dna complex assembly GO:0065004 105 0.010
positive regulation of phosphate metabolic process GO:0045937 147 0.010
nucleoside catabolic process GO:0009164 335 0.010

RPN11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org