Saccharomyces cerevisiae

33 known processes

HEM2 (YGL040C)

Hem2p

(Aliases: OLE4,SLU1)

HEM2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cofactor biosynthetic process GO:0051188 80 0.918
cofactor metabolic process GO:0051186 126 0.653
porphyrin containing compound metabolic process GO:0006778 15 0.575
single organism cellular localization GO:1902580 375 0.483
organonitrogen compound biosynthetic process GO:1901566 314 0.474
heme biosynthetic process GO:0006783 14 0.286
protein localization to organelle GO:0033365 337 0.256
establishment of protein localization to mitochondrion GO:0072655 63 0.234
tetrapyrrole metabolic process GO:0033013 15 0.218
establishment of protein localization GO:0045184 367 0.188
establishment of protein localization to organelle GO:0072594 278 0.183
pigment biosynthetic process GO:0046148 22 0.179
small molecule biosynthetic process GO:0044283 258 0.179
protein localization to mitochondrion GO:0070585 63 0.159
tetrapyrrole biosynthetic process GO:0033014 14 0.103
protein targeting GO:0006605 272 0.100
organophosphate metabolic process GO:0019637 597 0.091
lipid metabolic process GO:0006629 269 0.090
intracellular protein transport GO:0006886 319 0.087
nucleoside phosphate metabolic process GO:0006753 458 0.086
pigment metabolic process GO:0042440 23 0.080
coenzyme biosynthetic process GO:0009108 66 0.070
carbohydrate derivative metabolic process GO:1901135 549 0.067
establishment of protein localization to membrane GO:0090150 99 0.063
protein transport GO:0015031 345 0.063
intracellular protein transmembrane transport GO:0065002 80 0.063
energy derivation by oxidation of organic compounds GO:0015980 125 0.062
response to chemical GO:0042221 390 0.062
nucleotide metabolic process GO:0009117 453 0.060
single organism catabolic process GO:0044712 619 0.059
lipid biosynthetic process GO:0008610 170 0.054
purine containing compound metabolic process GO:0072521 400 0.054
purine ribonucleoside metabolic process GO:0046128 380 0.053
carboxylic acid biosynthetic process GO:0046394 152 0.052
ribonucleoside metabolic process GO:0009119 389 0.052
aerobic respiration GO:0009060 55 0.047
nucleoside metabolic process GO:0009116 394 0.047
cellular respiration GO:0045333 82 0.044
organic acid biosynthetic process GO:0016053 152 0.044
generation of precursor metabolites and energy GO:0006091 147 0.044
vitamin biosynthetic process GO:0009110 38 0.043
regulation of biological quality GO:0065008 391 0.042
monocarboxylic acid metabolic process GO:0032787 122 0.040
glycosyl compound metabolic process GO:1901657 398 0.040
membrane organization GO:0061024 276 0.039
alpha amino acid metabolic process GO:1901605 124 0.039
reproduction of a single celled organism GO:0032505 191 0.038
purine nucleoside metabolic process GO:0042278 380 0.037
sulfur compound biosynthetic process GO:0044272 53 0.037
protein import GO:0017038 122 0.036
mitochondrial transport GO:0006839 76 0.036
reproductive process GO:0022414 248 0.035
nucleobase containing compound transport GO:0015931 124 0.034
single organism membrane organization GO:0044802 275 0.034
alcohol metabolic process GO:0006066 112 0.033
nucleobase containing small molecule metabolic process GO:0055086 491 0.033
protein complex assembly GO:0006461 302 0.033
sexual reproduction GO:0019953 216 0.032
single organism reproductive process GO:0044702 159 0.032
ncrna processing GO:0034470 330 0.032
coenzyme metabolic process GO:0006732 104 0.031
cellular amino acid biosynthetic process GO:0008652 118 0.030
nicotinamide nucleotide metabolic process GO:0046496 44 0.030
carboxylic acid metabolic process GO:0019752 338 0.029
alpha amino acid biosynthetic process GO:1901607 91 0.029
intracellular protein transmembrane import GO:0044743 67 0.029
cellular response to chemical stimulus GO:0070887 315 0.029
protein complex biogenesis GO:0070271 314 0.028
regulation of protein metabolic process GO:0051246 237 0.028
oxoacid metabolic process GO:0043436 351 0.028
transmembrane transport GO:0055085 349 0.027
protein catabolic process GO:0030163 221 0.027
water soluble vitamin biosynthetic process GO:0042364 38 0.026
aromatic compound catabolic process GO:0019439 491 0.026
ascospore formation GO:0030437 107 0.026
growth GO:0040007 157 0.026
proteolysis GO:0006508 268 0.026
phosphorylation GO:0016310 291 0.026
oxidoreduction coenzyme metabolic process GO:0006733 58 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.024
gtp metabolic process GO:0046039 107 0.024
purine nucleoside triphosphate catabolic process GO:0009146 329 0.024
gtp catabolic process GO:0006184 107 0.023
mitochondrion organization GO:0007005 261 0.023
ion transport GO:0006811 274 0.023
organonitrogen compound catabolic process GO:1901565 404 0.023
nucleoside triphosphate metabolic process GO:0009141 364 0.023
protein insertion into membrane GO:0051205 13 0.023
cellular amide metabolic process GO:0043603 59 0.022
purine containing compound catabolic process GO:0072523 332 0.022
regulation of cellular component organization GO:0051128 334 0.022
translational elongation GO:0006414 32 0.022
carbohydrate derivative transport GO:1901264 27 0.022
nucleocytoplasmic transport GO:0006913 163 0.022
organic acid transport GO:0015849 77 0.022
multi organism process GO:0051704 233 0.021
homeostatic process GO:0042592 227 0.021
nucleobase containing compound catabolic process GO:0034655 479 0.021
ribose phosphate metabolic process GO:0019693 384 0.021
sexual sporulation GO:0034293 113 0.021
organic acid metabolic process GO:0006082 352 0.021
cell development GO:0048468 107 0.020
nitrogen compound transport GO:0071705 212 0.020
protein localization to membrane GO:0072657 102 0.020
establishment of rna localization GO:0051236 92 0.020
vitamin metabolic process GO:0006766 41 0.020
purine ribonucleoside catabolic process GO:0046130 330 0.020
cell differentiation GO:0030154 161 0.020
positive regulation of catabolic process GO:0009896 135 0.019
reproductive process in single celled organism GO:0022413 145 0.019
cellular response to oxidative stress GO:0034599 94 0.019
sporulation resulting in formation of a cellular spore GO:0030435 129 0.019
oxidation reduction process GO:0055114 353 0.019
protein phosphorylation GO:0006468 197 0.019
regulation of cellular component biogenesis GO:0044087 112 0.019
organic anion transport GO:0015711 114 0.019
chemical homeostasis GO:0048878 137 0.019
purine nucleotide catabolic process GO:0006195 328 0.018
metal ion transport GO:0030001 75 0.018
cellular amino acid metabolic process GO:0006520 225 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.018
macromolecule catabolic process GO:0009057 383 0.018
anion transport GO:0006820 145 0.018
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.018
single organism developmental process GO:0044767 258 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.018
aging GO:0007568 71 0.018
porphyrin containing compound biosynthetic process GO:0006779 14 0.018
purine nucleoside catabolic process GO:0006152 330 0.017
response to organic substance GO:0010033 182 0.017
protein transmembrane transport GO:0071806 82 0.017
glycosyl compound catabolic process GO:1901658 335 0.017
cellular response to dna damage stimulus GO:0006974 287 0.017
ribonucleoside triphosphate metabolic process GO:0009199 356 0.017
guanosine containing compound catabolic process GO:1901069 109 0.017
rna localization GO:0006403 112 0.017
developmental process involved in reproduction GO:0003006 159 0.016
cellular developmental process GO:0048869 191 0.016
ribosome biogenesis GO:0042254 335 0.016
positive regulation of gene expression GO:0010628 321 0.016
developmental process GO:0032502 261 0.016
response to organic cyclic compound GO:0014070 1 0.016
nucleoside catabolic process GO:0009164 335 0.016
nucleoside triphosphate catabolic process GO:0009143 329 0.016
phospholipid biosynthetic process GO:0008654 89 0.016
posttranscriptional regulation of gene expression GO:0010608 115 0.016
carbohydrate derivative catabolic process GO:1901136 339 0.016
nuclear transport GO:0051169 165 0.016
multi organism reproductive process GO:0044703 216 0.016
negative regulation of cellular metabolic process GO:0031324 407 0.016
protein targeting to mitochondrion GO:0006626 56 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.016
purine ribonucleotide metabolic process GO:0009150 372 0.016
regulation of translation GO:0006417 89 0.015
phospholipid metabolic process GO:0006644 125 0.015
sporulation GO:0043934 132 0.015
organophosphate biosynthetic process GO:0090407 182 0.015
carboxylic acid transport GO:0046942 74 0.015
regulation of organelle organization GO:0033043 243 0.015
regulation of dna metabolic process GO:0051052 100 0.015
heme metabolic process GO:0042168 15 0.015
cellular homeostasis GO:0019725 138 0.015
cellular lipid metabolic process GO:0044255 229 0.015
regulation of catabolic process GO:0009894 199 0.015
glycerophospholipid biosynthetic process GO:0046474 68 0.014
ribonucleotide metabolic process GO:0009259 377 0.014
rna transport GO:0050658 92 0.014
response to oxidative stress GO:0006979 99 0.014
transition metal ion transport GO:0000041 45 0.014
regulation of cellular protein metabolic process GO:0032268 232 0.014
organophosphate ester transport GO:0015748 45 0.014
meiotic cell cycle process GO:1903046 229 0.014
single organism membrane fusion GO:0044801 71 0.014
rrna metabolic process GO:0016072 244 0.014
heterocycle catabolic process GO:0046700 494 0.014
vacuolar transport GO:0007034 145 0.014
cellular modified amino acid metabolic process GO:0006575 51 0.014
metal ion homeostasis GO:0055065 79 0.014
regulation of cellular catabolic process GO:0031329 195 0.014
mitochondrial genome maintenance GO:0000002 40 0.014
ion homeostasis GO:0050801 118 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.014
ribonucleotide catabolic process GO:0009261 327 0.014
cell cycle phase transition GO:0044770 144 0.014
anatomical structure morphogenesis GO:0009653 160 0.014
cellular macromolecule catabolic process GO:0044265 363 0.014
sulfur compound metabolic process GO:0006790 95 0.014
cofactor transport GO:0051181 16 0.013
positive regulation of cellular component organization GO:0051130 116 0.013
ribonucleoside catabolic process GO:0042454 332 0.013
protein maturation GO:0051604 76 0.013
guanosine containing compound metabolic process GO:1901068 111 0.013
tricarboxylic acid metabolic process GO:0072350 3 0.013
positive regulation of molecular function GO:0044093 185 0.013
regulation of catalytic activity GO:0050790 307 0.013
negative regulation of cellular biosynthetic process GO:0031327 312 0.013
organic acid catabolic process GO:0016054 71 0.013
chromatin organization GO:0006325 242 0.013
peroxisome organization GO:0007031 68 0.013
positive regulation of cell death GO:0010942 3 0.013
nad metabolic process GO:0019674 25 0.013
cell division GO:0051301 205 0.013
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 96 0.012
protein lipidation GO:0006497 40 0.012
positive regulation of apoptotic process GO:0043065 3 0.012
dna replication GO:0006260 147 0.012
cell communication GO:0007154 345 0.012
cell wall organization GO:0071555 146 0.012
nadh metabolic process GO:0006734 12 0.012
mitotic cell cycle GO:0000278 306 0.012
endosomal transport GO:0016197 86 0.012
carboxylic acid catabolic process GO:0046395 71 0.012
cation homeostasis GO:0055080 105 0.012
positive regulation of programmed cell death GO:0043068 3 0.012
trna metabolic process GO:0006399 151 0.012
regulation of cell division GO:0051302 113 0.012
signaling GO:0023052 208 0.012
ribonucleoprotein complex subunit organization GO:0071826 152 0.012
nucleoside phosphate catabolic process GO:1901292 331 0.012
negative regulation of macromolecule metabolic process GO:0010605 375 0.011
organic hydroxy compound metabolic process GO:1901615 125 0.011
cell aging GO:0007569 70 0.011
protein processing GO:0016485 64 0.011
nucleotide catabolic process GO:0009166 330 0.011
positive regulation of cellular catabolic process GO:0031331 128 0.011
regulation of dna replication GO:0006275 51 0.011
carbohydrate metabolic process GO:0005975 252 0.011
regulation of cellular ketone metabolic process GO:0010565 42 0.011
cellular cation homeostasis GO:0030003 100 0.011
dephosphorylation GO:0016311 127 0.011
positive regulation of macromolecule metabolic process GO:0010604 394 0.011
organic hydroxy compound biosynthetic process GO:1901617 81 0.011
conjugation with cellular fusion GO:0000747 106 0.011
replicative cell aging GO:0001302 46 0.011
mitotic cell cycle process GO:1903047 294 0.011
ribonucleoside triphosphate catabolic process GO:0009203 327 0.011
protein insertion into membrane from inner side GO:0032978 6 0.011
fungal type cell wall organization GO:0031505 145 0.010
cell cycle checkpoint GO:0000075 82 0.010
cellular protein catabolic process GO:0044257 213 0.010
covalent chromatin modification GO:0016569 119 0.010
response to inorganic substance GO:0010035 47 0.010
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
single organism carbohydrate metabolic process GO:0044723 237 0.010
cellular nitrogen compound catabolic process GO:0044270 494 0.010
purine nucleoside monophosphate metabolic process GO:0009126 262 0.010
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.010
single organism signaling GO:0044700 208 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.010
membrane lipid metabolic process GO:0006643 67 0.010

HEM2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023