Saccharomyces cerevisiae

141 known processes

KEM1 (YGL173C)

Kem1p

(Aliases: SKI1,SEP1,RAR5,DST2,XRN1)

KEM1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna metabolic process GO:0016071 269 0.984
nuclear transcribed mrna catabolic process GO:0000956 89 0.936
macromolecule catabolic process GO:0009057 383 0.928
rna catabolic process GO:0006401 118 0.925
aromatic compound catabolic process GO:0019439 491 0.902
cellular macromolecule catabolic process GO:0044265 363 0.893
organic cyclic compound catabolic process GO:1901361 499 0.836
cellular nitrogen compound catabolic process GO:0044270 494 0.793
mrna processing GO:0006397 185 0.738
heterocycle catabolic process GO:0046700 494 0.708
establishment of rna localization GO:0051236 92 0.669
nucleobase containing compound catabolic process GO:0034655 479 0.668
nucleocytoplasmic transport GO:0006913 163 0.626
ncrna processing GO:0034470 330 0.602
translation GO:0006412 230 0.586
nuclear transport GO:0051169 165 0.546
ribosome biogenesis GO:0042254 335 0.491
multi organism cellular process GO:0044764 120 0.411
rna transport GO:0050658 92 0.411
mrna catabolic process GO:0006402 93 0.371
nucleic acid transport GO:0050657 94 0.369
negative regulation of biosynthetic process GO:0009890 312 0.356
rna localization GO:0006403 112 0.354
vesicle mediated transport GO:0016192 335 0.349
rna splicing via transesterification reactions GO:0000375 118 0.345
positive regulation of cellular component organization GO:0051130 116 0.336
cellular response to chemical stimulus GO:0070887 315 0.329
cellular response to nutrient levels GO:0031669 144 0.304
filamentous growth GO:0030447 124 0.296
nuclear export GO:0051168 124 0.261
carbohydrate derivative metabolic process GO:1901135 549 0.255
regulation of intracellular signal transduction GO:1902531 78 0.252
mitotic cell cycle process GO:1903047 294 0.243
rna export from nucleus GO:0006405 88 0.238
negative regulation of cellular biosynthetic process GO:0031327 312 0.237
negative regulation of gene expression GO:0010629 312 0.235
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 109 0.210
regulation of translation GO:0006417 89 0.200
regulation of cellular component organization GO:0051128 334 0.191
response to chemical GO:0042221 390 0.189
ribonucleotide catabolic process GO:0009261 327 0.187
negative regulation of cellular metabolic process GO:0031324 407 0.181
proteolysis GO:0006508 268 0.178
mrna splicing via spliceosome GO:0000398 108 0.173
negative regulation of growth GO:0045926 13 0.170
multi organism reproductive process GO:0044703 216 0.165
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.164
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 44 0.161
conjugation with cellular fusion GO:0000747 106 0.156
cell division GO:0051301 205 0.155
cellular ketone metabolic process GO:0042180 63 0.152
nucleoside triphosphate metabolic process GO:0009141 364 0.152
lipid localization GO:0010876 60 0.152
gene silencing GO:0016458 151 0.147
organonitrogen compound catabolic process GO:1901565 404 0.145
regulation of gene expression epigenetic GO:0040029 147 0.140
cellular response to dna damage stimulus GO:0006974 287 0.138
nucleoside phosphate catabolic process GO:1901292 331 0.137
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.135
negative regulation of intracellular signal transduction GO:1902532 27 0.133
lipid transport GO:0006869 58 0.132
growth GO:0040007 157 0.129
rna splicing GO:0008380 131 0.128
regulation of organelle organization GO:0033043 243 0.125
nucleoside catabolic process GO:0009164 335 0.122
regulation of anatomical structure size GO:0090066 50 0.119
ribonucleotide metabolic process GO:0009259 377 0.116
double strand break repair GO:0006302 105 0.116
ribonucleoprotein complex assembly GO:0022618 143 0.111
regulation of translational elongation GO:0006448 25 0.108
multi organism process GO:0051704 233 0.108
ribonucleoside catabolic process GO:0042454 332 0.105
cell wall organization or biogenesis GO:0071554 190 0.103
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.103
purine ribonucleoside catabolic process GO:0046130 330 0.102
positive regulation of cellular catabolic process GO:0031331 128 0.100
regulation of protein metabolic process GO:0051246 237 0.100
negative regulation of macromolecule metabolic process GO:0010605 375 0.099
protein catabolic process GO:0030163 221 0.096
endocytosis GO:0006897 90 0.096
ribonucleoprotein complex subunit organization GO:0071826 152 0.095
purine nucleotide catabolic process GO:0006195 328 0.094
negative regulation of cellular protein metabolic process GO:0032269 85 0.090
glycosyl compound catabolic process GO:1901658 335 0.089
positive regulation of gene expression GO:0010628 321 0.089
purine containing compound catabolic process GO:0072523 332 0.087
nucleoside triphosphate catabolic process GO:0009143 329 0.086
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.085
reproductive process GO:0022414 248 0.082
cell cycle phase transition GO:0044770 144 0.081
ribonucleoside triphosphate catabolic process GO:0009203 327 0.080
posttranscriptional regulation of gene expression GO:0010608 115 0.080
cation homeostasis GO:0055080 105 0.079
cellular protein catabolic process GO:0044257 213 0.077
carbohydrate derivative biosynthetic process GO:1901137 181 0.077
response to pheromone GO:0019236 92 0.076
purine containing compound metabolic process GO:0072521 400 0.075
positive regulation of catalytic activity GO:0043085 178 0.075
conjugation GO:0000746 107 0.075
response to abiotic stimulus GO:0009628 159 0.074
homeostatic process GO:0042592 227 0.074
response to temperature stimulus GO:0009266 74 0.072
invasive growth in response to glucose limitation GO:0001403 61 0.072
purine ribonucleoside metabolic process GO:0046128 380 0.070
response to external stimulus GO:0009605 158 0.068
negative regulation of protein metabolic process GO:0051248 85 0.067
cell growth GO:0016049 89 0.067
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.065
protein acetylation GO:0006473 59 0.065
snorna processing GO:0043144 34 0.064
regulation of cell cycle process GO:0010564 150 0.064
stress granule assembly GO:0034063 8 0.063
mitotic cell cycle checkpoint GO:0007093 56 0.063
intracellular signal transduction GO:0035556 112 0.063
purine nucleoside monophosphate metabolic process GO:0009126 262 0.063
regulation of localization GO:0032879 127 0.062
regulation of cellular component biogenesis GO:0044087 112 0.061
purine nucleoside triphosphate catabolic process GO:0009146 329 0.061
filamentous growth of a population of unicellular organisms GO:0044182 109 0.061
purine nucleoside monophosphate catabolic process GO:0009128 224 0.061
purine nucleotide metabolic process GO:0006163 376 0.060
single organism developmental process GO:0044767 258 0.060
cellular ion homeostasis GO:0006873 112 0.059
protein targeting GO:0006605 272 0.058
positive regulation of protein complex assembly GO:0031334 39 0.058
invasive filamentous growth GO:0036267 65 0.058
regulation of carbohydrate metabolic process GO:0006109 43 0.057
organophosphate metabolic process GO:0019637 597 0.057
chromatin remodeling GO:0006338 80 0.057
establishment of protein localization GO:0045184 367 0.057
positive regulation of transport GO:0051050 32 0.056
cellular response to external stimulus GO:0071496 150 0.055
regulation of cellular component size GO:0032535 50 0.055
regulation of invasive growth in response to glucose limitation GO:2000217 19 0.055
carbohydrate derivative catabolic process GO:1901136 339 0.055
organonitrogen compound biosynthetic process GO:1901566 314 0.054
positive regulation of endocytosis GO:0045807 12 0.054
purine ribonucleotide catabolic process GO:0009154 327 0.054
positive regulation of cellular protein metabolic process GO:0032270 89 0.053
ribonucleoside triphosphate metabolic process GO:0009199 356 0.052
response to osmotic stress GO:0006970 83 0.052
response to heat GO:0009408 69 0.052
nuclear mrna surveillance GO:0071028 22 0.051
Human
dna conformation change GO:0071103 98 0.051
translational elongation GO:0006414 32 0.051
cellular metal ion homeostasis GO:0006875 78 0.051
nucleotide excision repair GO:0006289 50 0.049
positive regulation of cellular component biogenesis GO:0044089 45 0.049
negative regulation of cell cycle phase transition GO:1901988 59 0.048
purine nucleoside metabolic process GO:0042278 380 0.048
atp catabolic process GO:0006200 224 0.047
nuclear rna surveillance GO:0071027 30 0.047
Human
regulation of cell size GO:0008361 30 0.045
single organism catabolic process GO:0044712 619 0.045
snorna metabolic process GO:0016074 40 0.045
regulation of cellular amine metabolic process GO:0033238 21 0.045
carbon catabolite regulation of transcription GO:0045990 39 0.044
regulation of biological quality GO:0065008 391 0.044
regulation of signaling GO:0023051 119 0.043
response to nutrient GO:0007584 52 0.042
regulation of lipid metabolic process GO:0019216 45 0.042
dna repair GO:0006281 236 0.042
sexual reproduction GO:0019953 216 0.042
organelle fission GO:0048285 272 0.041
glycogen metabolic process GO:0005977 30 0.040
single organism cellular localization GO:1902580 375 0.039
regulation of metal ion transport GO:0010959 2 0.039
gene silencing by rna GO:0031047 3 0.038
cellular chemical homeostasis GO:0055082 123 0.038
ion homeostasis GO:0050801 118 0.037
fatty acid beta oxidation GO:0006635 12 0.037
nucleoside metabolic process GO:0009116 394 0.037
regulation of lipid catabolic process GO:0050994 4 0.037
dna duplex unwinding GO:0032508 42 0.036
mrna 3 end processing GO:0031124 54 0.036
positive regulation of macromolecule metabolic process GO:0010604 394 0.036
organelle inheritance GO:0048308 51 0.036
regulation of molecular function GO:0065009 320 0.036
chromatin organization GO:0006325 242 0.036
mitotic cell cycle GO:0000278 306 0.035
nucleoside monophosphate catabolic process GO:0009125 224 0.035
gtp metabolic process GO:0046039 107 0.034
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.034
glycosyl compound metabolic process GO:1901657 398 0.034
regulation of filamentous growth GO:0010570 38 0.034
purine nucleoside catabolic process GO:0006152 330 0.033
cellular carbohydrate metabolic process GO:0044262 135 0.033
regulation of lipid biosynthetic process GO:0046890 32 0.033
dna templated transcription elongation GO:0006354 91 0.032
developmental process GO:0032502 261 0.032
positive regulation of organelle organization GO:0010638 85 0.032
cellular lipid metabolic process GO:0044255 229 0.032
rrna processing GO:0006364 227 0.032
regulation of cellular catabolic process GO:0031329 195 0.031
chromatin silencing GO:0006342 147 0.031
regulation of protein complex assembly GO:0043254 77 0.031
anatomical structure formation involved in morphogenesis GO:0048646 136 0.030
sporulation resulting in formation of a cellular spore GO:0030435 129 0.030
regulation of cellular protein metabolic process GO:0032268 232 0.029
cellular response to extracellular stimulus GO:0031668 150 0.029
regulation of rna splicing GO:0043484 3 0.029
nucleotide catabolic process GO:0009166 330 0.029
dna recombination GO:0006310 172 0.029
cell differentiation GO:0030154 161 0.029
regulation of transcription by chromatin organization GO:0034401 19 0.028
positive regulation of catabolic process GO:0009896 135 0.028
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.028
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.028
transcription elongation from rna polymerase ii promoter GO:0006368 81 0.028
cellular carbohydrate biosynthetic process GO:0034637 49 0.028
ribonucleoside monophosphate metabolic process GO:0009161 265 0.028
positive regulation of apoptotic process GO:0043065 3 0.028
amine metabolic process GO:0009308 51 0.027
regulation of catabolic process GO:0009894 199 0.027
cellular amine metabolic process GO:0044106 51 0.027
protein modification by small protein conjugation GO:0032446 144 0.027
organophosphate catabolic process GO:0046434 338 0.026
cell cycle checkpoint GO:0000075 82 0.026
regulation of dna templated transcription elongation GO:0032784 44 0.026
cellular response to nutrient GO:0031670 50 0.026
mitotic dna integrity checkpoint GO:0044774 18 0.026
nucleotide metabolic process GO:0009117 453 0.025
mitotic nuclear division GO:0007067 131 0.025
chromosome localization GO:0050000 20 0.025
regulation of filamentous growth of a population of unicellular organisms GO:1900428 36 0.024
dna geometric change GO:0032392 43 0.024
dna replication GO:0006260 147 0.024
regulation of translational initiation GO:0006446 18 0.023
single organism signaling GO:0044700 208 0.023
purine nucleoside triphosphate metabolic process GO:0009144 356 0.023
response to pheromone involved in conjugation with cellular fusion GO:0000749 74 0.023
ribose phosphate metabolic process GO:0019693 384 0.023
regulation of response to stimulus GO:0048583 157 0.022
cellular response to heat GO:0034605 53 0.022
gtp catabolic process GO:0006184 107 0.022
response to organic cyclic compound GO:0014070 1 0.022
protein import GO:0017038 122 0.022
cellular response to organic substance GO:0071310 159 0.022
negative regulation of invasive growth in response to glucose limitation GO:2000218 6 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.022
organic acid metabolic process GO:0006082 352 0.022
rrna metabolic process GO:0016072 244 0.022
purine ribonucleotide metabolic process GO:0009150 372 0.022
meiotic nuclear division GO:0007126 163 0.021
protein ubiquitination GO:0016567 118 0.021
protein modification by small protein conjugation or removal GO:0070647 172 0.021
apoptotic process GO:0006915 30 0.021
cytoplasmic mrna processing body assembly GO:0033962 9 0.020
anatomical structure morphogenesis GO:0009653 160 0.020
regulation of carbohydrate biosynthetic process GO:0043255 31 0.020
metal ion homeostasis GO:0055065 79 0.020
pseudohyphal growth GO:0007124 75 0.020
membrane organization GO:0061024 276 0.020
regulation of cellular amino acid metabolic process GO:0006521 16 0.020
regulation of cell communication GO:0010646 124 0.020
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 15 0.020
regulation of cellular ketone metabolic process GO:0010565 42 0.020
response to hypoxia GO:0001666 4 0.020
positive regulation of gene expression epigenetic GO:0045815 25 0.020
regulation of growth GO:0040008 50 0.020
response to nutrient levels GO:0031667 150 0.019
cell death GO:0008219 30 0.019
positive regulation of dna templated transcription elongation GO:0032786 42 0.019
mitotic cell cycle phase transition GO:0044772 141 0.019
microtubule based process GO:0007017 117 0.019
cellular response to endogenous stimulus GO:0071495 22 0.019
cellular alcohol biosynthetic process GO:0044108 29 0.019
peptidyl lysine acetylation GO:0018394 52 0.019
mrna export from nucleus GO:0006406 60 0.019
carbohydrate metabolic process GO:0005975 252 0.019
cellular response to nitrogen compound GO:1901699 14 0.019
trna transport GO:0051031 19 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.018
regulation of cell cycle GO:0051726 195 0.018
tor signaling GO:0031929 17 0.018
cellular component disassembly GO:0022411 86 0.018
oxoacid metabolic process GO:0043436 351 0.018
maintenance of location GO:0051235 66 0.018
positive regulation of molecular function GO:0044093 185 0.018
lipid modification GO:0030258 37 0.018
translational initiation GO:0006413 56 0.018
nucleobase containing compound transport GO:0015931 124 0.018
cellular homeostasis GO:0019725 138 0.017
guanosine containing compound metabolic process GO:1901068 111 0.017
programmed cell death GO:0012501 30 0.017
negative regulation of rna metabolic process GO:0051253 262 0.017
death GO:0016265 30 0.017
protein modification by small protein removal GO:0070646 29 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.016
amino sugar metabolic process GO:0006040 20 0.016
chemical homeostasis GO:0048878 137 0.016
positive regulation of rna biosynthetic process GO:1902680 286 0.016
mitotic cytokinesis GO:0000281 58 0.016
negative regulation of catalytic activity GO:0043086 60 0.016
ribonucleoside metabolic process GO:0009119 389 0.016
g1 s transition of mitotic cell cycle GO:0000082 64 0.015
regulation of mrna splicing via spliceosome GO:0048024 3 0.015
chromatin assembly or disassembly GO:0006333 60 0.015
regulation of cell division GO:0051302 113 0.015
regulation of mitotic cell cycle phase transition GO:1901990 68 0.015
nucleosome organization GO:0034728 63 0.015
regulation of endocytosis GO:0030100 17 0.015
regulation of catalytic activity GO:0050790 307 0.015
response to uv GO:0009411 4 0.015
endosomal transport GO:0016197 86 0.015
macromolecular complex disassembly GO:0032984 80 0.015
telomere maintenance GO:0000723 74 0.015
negative regulation of gene expression epigenetic GO:0045814 147 0.015
negative regulation of cell communication GO:0010648 33 0.015
regulation of cell growth GO:0001558 29 0.015
cell wall biogenesis GO:0042546 93 0.015
non recombinational repair GO:0000726 33 0.015
polysaccharide metabolic process GO:0005976 60 0.015
cellular response to pheromone GO:0071444 88 0.014
mitotic spindle organization GO:0007052 30 0.014
phosphorylation GO:0016310 291 0.014
establishment of protein localization to organelle GO:0072594 278 0.014
response to extracellular stimulus GO:0009991 156 0.014
nucleobase containing small molecule metabolic process GO:0055086 491 0.014
organelle assembly GO:0070925 118 0.013
cell communication GO:0007154 345 0.013
positive regulation of cell death GO:0010942 3 0.013
double strand break repair via nonhomologous end joining GO:0006303 27 0.013
monocarboxylic acid transport GO:0015718 24 0.013
ribonucleoside monophosphate catabolic process GO:0009158 224 0.013
positive regulation of programmed cell death GO:0043068 3 0.013
establishment of protein localization to mitochondrial membrane GO:0090151 20 0.013
cellular response to osmotic stress GO:0071470 50 0.013
protein transport GO:0015031 345 0.013
organelle localization GO:0051640 128 0.013
positive regulation of rna metabolic process GO:0051254 294 0.012
positive regulation of nucleic acid templated transcription GO:1903508 286 0.012
positive regulation of peroxisome organization by positive regulation of transcription from rna polymerase ii promoter GO:0061424 1 0.012
surface biofilm formation GO:0090604 3 0.012
covalent chromatin modification GO:0016569 119 0.012
positive regulation of protein metabolic process GO:0051247 93 0.012
protein deubiquitination GO:0016579 17 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.012
positive regulation of cell cycle GO:0045787 32 0.012
regulation of fatty acid oxidation GO:0046320 3 0.012
positive regulation of lipid catabolic process GO:0050996 4 0.012
regulation of kinase activity GO:0043549 71 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.011
positive regulation of biosynthetic process GO:0009891 336 0.011
fungal type cell wall organization or biogenesis GO:0071852 169 0.011
regulation of response to nutrient levels GO:0032107 20 0.011
mrna transport GO:0051028 60 0.011
cytokinetic process GO:0032506 78 0.011
regulation of mrna metabolic process GO:1903311 17 0.011
cell development GO:0048468 107 0.011
regulation of purine nucleotide metabolic process GO:1900542 109 0.011
cellular developmental process GO:0048869 191 0.011
protein monoubiquitination GO:0006513 13 0.011
modification dependent protein catabolic process GO:0019941 181 0.011
carboxylic acid catabolic process GO:0046395 71 0.011
negative regulation of invasive growth in response to glucose limitation by negative regulation of transcription from rna polymerase ii promoter GO:1900460 3 0.011
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 34 0.011
ubiquitin dependent protein catabolic process GO:0006511 181 0.011
regulation of response to extracellular stimulus GO:0032104 20 0.011
membrane invagination GO:0010324 43 0.011
aminoglycan metabolic process GO:0006022 18 0.011
cellular response to oxidative stress GO:0034599 94 0.010
positive regulation of dna templated transcription initiation GO:2000144 13 0.010
negative regulation of response to stimulus GO:0048585 40 0.010
regulation of hydrolase activity GO:0051336 133 0.010
cytokinesis GO:0000910 92 0.010
establishment or maintenance of cell polarity GO:0007163 96 0.010
regulation of glucose metabolic process GO:0010906 27 0.010
atp metabolic process GO:0046034 251 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 97 0.010

KEM1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024