Saccharomyces cerevisiae

137 known processes

MDR1 (YGR100W)

Mdr1p

(Aliases: GYP2,MIC1)

MDR1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macromolecule catabolic process GO:0009057 383 0.208
single organism signaling GO:0044700 208 0.170
cellular macromolecule catabolic process GO:0044265 363 0.154
organophosphate metabolic process GO:0019637 597 0.150
ribonucleoside metabolic process GO:0009119 389 0.141
protein catabolic process GO:0030163 221 0.135
ribose phosphate metabolic process GO:0019693 384 0.134
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.127
signaling GO:0023052 208 0.122
vesicle mediated transport GO:0016192 335 0.122
Yeast
carbohydrate derivative metabolic process GO:1901135 549 0.121
aromatic compound catabolic process GO:0019439 491 0.121
glycosyl compound metabolic process GO:1901657 398 0.119
phospholipid metabolic process GO:0006644 125 0.114
cell communication GO:0007154 345 0.111
organic cyclic compound catabolic process GO:1901361 499 0.106
purine containing compound catabolic process GO:0072523 332 0.106
protein modification by small protein conjugation or removal GO:0070647 172 0.100
purine ribonucleotide metabolic process GO:0009150 372 0.099
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.098
nucleobase containing compound catabolic process GO:0034655 479 0.098
intracellular protein transport GO:0006886 319 0.096
purine nucleoside monophosphate metabolic process GO:0009126 262 0.095
protein localization to organelle GO:0033365 337 0.094
single organism cellular localization GO:1902580 375 0.093
ribonucleoside triphosphate metabolic process GO:0009199 356 0.091
modification dependent protein catabolic process GO:0019941 181 0.090
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.089
protein transport GO:0015031 345 0.088
nucleoside catabolic process GO:0009164 335 0.088
nucleoside phosphate metabolic process GO:0006753 458 0.088
intracellular signal transduction GO:0035556 112 0.087
regulation of intracellular signal transduction GO:1902531 78 0.086
cellular protein catabolic process GO:0044257 213 0.083
purine containing compound metabolic process GO:0072521 400 0.083
nucleoside triphosphate metabolic process GO:0009141 364 0.082
ribonucleotide metabolic process GO:0009259 377 0.081
signal transduction GO:0007165 208 0.079
purine ribonucleoside metabolic process GO:0046128 380 0.078
atp metabolic process GO:0046034 251 0.077
single organism catabolic process GO:0044712 619 0.075
purine nucleotide metabolic process GO:0006163 376 0.073
atp catabolic process GO:0006200 224 0.072
nucleoside triphosphate catabolic process GO:0009143 329 0.071
purine nucleoside catabolic process GO:0006152 330 0.071
organophosphate catabolic process GO:0046434 338 0.070
purine nucleoside metabolic process GO:0042278 380 0.070
ribonucleoside catabolic process GO:0042454 332 0.069
heterocycle catabolic process GO:0046700 494 0.069
purine nucleoside triphosphate metabolic process GO:0009144 356 0.068
nucleoside monophosphate metabolic process GO:0009123 267 0.067
phosphorylation GO:0016310 291 0.066
organonitrogen compound catabolic process GO:1901565 404 0.066
protein targeting GO:0006605 272 0.065
establishment of protein localization GO:0045184 367 0.065
regulation of cellular component organization GO:0051128 334 0.065
nucleotide catabolic process GO:0009166 330 0.063
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.062
endocytosis GO:0006897 90 0.061
Yeast
positive regulation of gene expression GO:0010628 321 0.057
regulation of cell communication GO:0010646 124 0.055
carbohydrate derivative catabolic process GO:1901136 339 0.055
glycosyl compound catabolic process GO:1901658 335 0.055
regulation of signaling GO:0023051 119 0.054
cellular response to chemical stimulus GO:0070887 315 0.054
proteolysis GO:0006508 268 0.052
protein ubiquitination GO:0016567 118 0.051
protein modification by small protein conjugation GO:0032446 144 0.051
regulation of signal transduction GO:0009966 114 0.051
lipid metabolic process GO:0006629 269 0.050
nuclear division GO:0000280 263 0.049
nucleotide metabolic process GO:0009117 453 0.048
reproductive process GO:0022414 248 0.048
filamentous growth of a population of unicellular organisms GO:0044182 109 0.048
positive regulation of macromolecule metabolic process GO:0010604 394 0.048
reproduction of a single celled organism GO:0032505 191 0.047
nucleoside phosphate catabolic process GO:1901292 331 0.047
regulation of vesicle mediated transport GO:0060627 39 0.047
retrograde transport endosome to golgi GO:0042147 33 0.047
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.046
dna repair GO:0006281 236 0.046
ribonucleoside monophosphate metabolic process GO:0009161 265 0.046
multi organism process GO:0051704 233 0.043
sexual reproduction GO:0019953 216 0.043
regulation of localization GO:0032879 127 0.042
Yeast
ribonucleoside triphosphate catabolic process GO:0009203 327 0.042
purine nucleotide catabolic process GO:0006195 328 0.041
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.040
multi organism reproductive process GO:0044703 216 0.040
ribonucleoside monophosphate catabolic process GO:0009158 224 0.040
carbohydrate metabolic process GO:0005975 252 0.039
regulation of biological quality GO:0065008 391 0.039
nucleoside metabolic process GO:0009116 394 0.039
cellular nitrogen compound catabolic process GO:0044270 494 0.038
purine ribonucleoside catabolic process GO:0046130 330 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.038
cellular lipid metabolic process GO:0044255 229 0.038
glycerolipid metabolic process GO:0046486 108 0.038
cellular amino acid biosynthetic process GO:0008652 118 0.037
single organism reproductive process GO:0044702 159 0.037
meiotic cell cycle process GO:1903046 229 0.036
ribonucleotide catabolic process GO:0009261 327 0.035
regulation of response to stimulus GO:0048583 157 0.035
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.035
nucleoside monophosphate catabolic process GO:0009125 224 0.034
dephosphorylation GO:0016311 127 0.034
filamentous growth GO:0030447 124 0.034
establishment of protein localization to organelle GO:0072594 278 0.034
purine nucleoside triphosphate catabolic process GO:0009146 329 0.033
ubiquitin dependent protein catabolic process GO:0006511 181 0.033
regulation of protein metabolic process GO:0051246 237 0.033
mitotic cell cycle process GO:1903047 294 0.032
cell growth GO:0016049 89 0.031
modification dependent macromolecule catabolic process GO:0043632 203 0.031
purine ribonucleotide catabolic process GO:0009154 327 0.031
conjugation GO:0000746 107 0.031
nucleobase containing small molecule metabolic process GO:0055086 491 0.031
regulation of endocytosis GO:0030100 17 0.031
glycerophospholipid metabolic process GO:0006650 98 0.031
golgi vesicle transport GO:0048193 188 0.031
proteasomal protein catabolic process GO:0010498 141 0.030
response to external stimulus GO:0009605 158 0.030
anatomical structure morphogenesis GO:0009653 160 0.030
growth GO:0040007 157 0.029
fungal type cell wall organization GO:0031505 145 0.029
cellular protein complex assembly GO:0043623 209 0.028
protein localization to membrane GO:0072657 102 0.028
cell division GO:0051301 205 0.028
single organism developmental process GO:0044767 258 0.027
ion homeostasis GO:0050801 118 0.027
reproductive process in single celled organism GO:0022413 145 0.027
alpha amino acid biosynthetic process GO:1901607 91 0.027
protein deubiquitination GO:0016579 17 0.026
negative regulation of gene expression GO:0010629 312 0.026
response to chemical GO:0042221 390 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.026
regulation of molecular function GO:0065009 320 0.026
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.026
regulation of transport GO:0051049 85 0.026
ncrna processing GO:0034470 330 0.026
positive regulation of rna metabolic process GO:0051254 294 0.026
cellular response to dna damage stimulus GO:0006974 287 0.025
regulation of cellular component biogenesis GO:0044087 112 0.025
gtp catabolic process GO:0006184 107 0.025
negative regulation of cellular metabolic process GO:0031324 407 0.025
regulation of cellular protein metabolic process GO:0032268 232 0.025
meiotic cell cycle GO:0051321 272 0.025
regulation of organelle organization GO:0033043 243 0.025
glycerophospholipid biosynthetic process GO:0046474 68 0.024
protein complex disassembly GO:0043241 70 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.024
regulation of filamentous growth GO:0010570 38 0.024
negative regulation of cellular component organization GO:0051129 109 0.024
phosphatidylinositol metabolic process GO:0046488 62 0.023
protein dephosphorylation GO:0006470 40 0.023
fungal type cell wall organization or biogenesis GO:0071852 169 0.023
regulation of phosphorus metabolic process GO:0051174 230 0.023
organelle fission GO:0048285 272 0.022
regulation of receptor mediated endocytosis GO:0048259 4 0.021
alpha amino acid metabolic process GO:1901605 124 0.021
purine nucleoside monophosphate catabolic process GO:0009128 224 0.021
organic acid biosynthetic process GO:0016053 152 0.021
organophosphate biosynthetic process GO:0090407 182 0.021
vacuolar transport GO:0007034 145 0.021
sporulation resulting in formation of a cellular spore GO:0030435 129 0.021
transmembrane transport GO:0055085 349 0.021
cellular developmental process GO:0048869 191 0.021
protein modification by small protein removal GO:0070646 29 0.021
cellular cation homeostasis GO:0030003 100 0.020
nucleobase containing compound transport GO:0015931 124 0.020
golgi to vacuole transport GO:0006896 23 0.020
membrane lipid metabolic process GO:0006643 67 0.020
coenzyme biosynthetic process GO:0009108 66 0.020
rrna metabolic process GO:0016072 244 0.020
pseudohyphal growth GO:0007124 75 0.020
negative regulation of transcription dna templated GO:0045892 258 0.019
organelle fusion GO:0048284 85 0.019
dna dependent dna replication GO:0006261 115 0.019
homeostatic process GO:0042592 227 0.019
cellular ion homeostasis GO:0006873 112 0.019
recombinational repair GO:0000725 64 0.019
response to starvation GO:0042594 96 0.019
cellular response to extracellular stimulus GO:0031668 150 0.019
signal transduction involved in conjugation with cellular fusion GO:0032005 31 0.019
endosomal transport GO:0016197 86 0.018
multi organism cellular process GO:0044764 120 0.018
regulation of purine nucleotide metabolic process GO:1900542 109 0.018
single organism membrane organization GO:0044802 275 0.018
anatomical structure formation involved in morphogenesis GO:0048646 136 0.018
cellular response to organic substance GO:0071310 159 0.018
cell surface receptor signaling pathway GO:0007166 38 0.018
guanosine containing compound catabolic process GO:1901069 109 0.018
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.018
cell cycle phase transition GO:0044770 144 0.018
positive regulation of cellular component organization GO:0051130 116 0.018
response to topologically incorrect protein GO:0035966 38 0.018
regulation of nucleotide metabolic process GO:0006140 110 0.017
response to pheromone involved in conjugation with cellular fusion GO:0000749 74 0.017
protein phosphorylation GO:0006468 197 0.017
single organism carbohydrate metabolic process GO:0044723 237 0.017
positive regulation of biosynthetic process GO:0009891 336 0.017
chromatin organization GO:0006325 242 0.017
positive regulation of cell death GO:0010942 3 0.017
protein complex assembly GO:0006461 302 0.016
dna integrity checkpoint GO:0031570 41 0.016
dna replication GO:0006260 147 0.016
response to organic substance GO:0010033 182 0.016
regulation of gtpase activity GO:0043087 84 0.016
establishment of organelle localization GO:0051656 96 0.016
positive regulation of molecular function GO:0044093 185 0.016
establishment of protein localization to membrane GO:0090150 99 0.016
positive regulation of endocytosis GO:0045807 12 0.016
mitotic cell cycle phase transition GO:0044772 141 0.015
regulation of catabolic process GO:0009894 199 0.015
g protein coupled receptor signaling pathway GO:0007186 37 0.015
cellular amino acid catabolic process GO:0009063 48 0.015
developmental process GO:0032502 261 0.015
cellular modified amino acid metabolic process GO:0006575 51 0.015
invasive filamentous growth GO:0036267 65 0.015
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.015
regulation of nucleoside metabolic process GO:0009118 106 0.015
phospholipid biosynthetic process GO:0008654 89 0.015
macromolecular complex disassembly GO:0032984 80 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.015
cell wall organization or biogenesis GO:0071554 190 0.015
rrna processing GO:0006364 227 0.015
carboxylic acid metabolic process GO:0019752 338 0.014
regulation of phosphate metabolic process GO:0019220 230 0.014
cellular component disassembly GO:0022411 86 0.014
single organism membrane fusion GO:0044801 71 0.014
chromatin assembly GO:0031497 35 0.014
regulation of catalytic activity GO:0050790 307 0.014
negative regulation of nucleic acid templated transcription GO:1903507 260 0.014
cellular homeostasis GO:0019725 138 0.014
rna catabolic process GO:0006401 118 0.014
dna recombination GO:0006310 172 0.013
organic hydroxy compound transport GO:0015850 41 0.013
sexual sporulation GO:0034293 113 0.013
protein targeting to vacuole GO:0006623 91 0.013
anatomical structure development GO:0048856 160 0.013
regulation of cell cycle GO:0051726 195 0.013
response to extracellular stimulus GO:0009991 156 0.013
late endosome to vacuole transport GO:0045324 42 0.013
positive regulation of transcription dna templated GO:0045893 286 0.013
mitotic cell cycle GO:0000278 306 0.013
cellular carbohydrate metabolic process GO:0044262 135 0.013
cation homeostasis GO:0055080 105 0.012
protein targeting to membrane GO:0006612 52 0.012
protein polyubiquitination GO:0000209 20 0.012
cell cycle checkpoint GO:0000075 82 0.012
regulation of protein modification process GO:0031399 110 0.012
regulation of cell cycle process GO:0010564 150 0.012
regulation of protein complex assembly GO:0043254 77 0.012
negative regulation of signaling GO:0023057 30 0.012
oxoacid metabolic process GO:0043436 351 0.012
cellular glucan metabolic process GO:0006073 44 0.012
organelle localization GO:0051640 128 0.012
cellular protein complex disassembly GO:0043624 42 0.012
regulation of hydrolase activity GO:0051336 133 0.012
rna localization GO:0006403 112 0.012
coenzyme metabolic process GO:0006732 104 0.012
positive regulation of cellular biosynthetic process GO:0031328 336 0.012
nuclear export GO:0051168 124 0.012
conjugation with cellular fusion GO:0000747 106 0.012
mitochondrial transport GO:0006839 76 0.012
regulation of protein localization GO:0032880 62 0.012
Yeast
cellular component morphogenesis GO:0032989 97 0.012
cell differentiation GO:0030154 161 0.012
response to nutrient levels GO:0031667 150 0.011
positive regulation of phosphorus metabolic process GO:0010562 147 0.011
transition metal ion transport GO:0000041 45 0.011
membrane organization GO:0061024 276 0.011
gtp metabolic process GO:0046039 107 0.011
negative regulation of rna biosynthetic process GO:1902679 260 0.011
negative regulation of macromolecule metabolic process GO:0010605 375 0.011
late endosome to vacuole transport via multivesicular body sorting pathway GO:0032511 26 0.011
mitochondrial genome maintenance GO:0000002 40 0.011
regulation of small gtpase mediated signal transduction GO:0051056 47 0.011
establishment of protein localization to vacuole GO:0072666 91 0.011
positive regulation of rna biosynthetic process GO:1902680 286 0.011
posttranscriptional regulation of gene expression GO:0010608 115 0.011
serine family amino acid metabolic process GO:0009069 25 0.011
protein complex biogenesis GO:0070271 314 0.011
mitochondrion organization GO:0007005 261 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
negative regulation of organelle organization GO:0010639 103 0.011
regulation of cellular catabolic process GO:0031329 195 0.011
nitrogen compound transport GO:0071705 212 0.011
guanosine containing compound metabolic process GO:1901068 111 0.011
cellular response to external stimulus GO:0071496 150 0.011
chemical homeostasis GO:0048878 137 0.010
negative regulation of protein metabolic process GO:0051248 85 0.010
cofactor biosynthetic process GO:0051188 80 0.010
regulation of purine nucleotide catabolic process GO:0033121 106 0.010
external encapsulating structure organization GO:0045229 146 0.010
regulation of mitotic cell cycle phase transition GO:1901990 68 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.010
negative regulation of rna metabolic process GO:0051253 262 0.010
positive regulation of programmed cell death GO:0043068 3 0.010
regulation of transmembrane transporter activity GO:0022898 1 0.010
cellular polysaccharide metabolic process GO:0044264 55 0.010
regulation of mitotic cell cycle GO:0007346 107 0.010
positive regulation of apoptotic process GO:0043065 3 0.010

MDR1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.014