Saccharomyces cerevisiae

34 known processes

RPN2 (YIL075C)

Rpn2p

(Aliases: SEN3)

RPN2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteasome assembly GO:0043248 31 0.933
cellular protein complex assembly GO:0043623 209 0.891
proteolysis GO:0006508 268 0.878
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.830
proteasome regulatory particle assembly GO:0070682 11 0.763
protein complex biogenesis GO:0070271 314 0.606
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.605
ubiquitin dependent protein catabolic process GO:0006511 181 0.557
protein catabolic process GO:0030163 221 0.523
modification dependent protein catabolic process GO:0019941 181 0.503
macromolecule catabolic process GO:0009057 383 0.455
protein complex assembly GO:0006461 302 0.433
proteasomal protein catabolic process GO:0010498 141 0.391
positive regulation of cellular biosynthetic process GO:0031328 336 0.352
positive regulation of macromolecule metabolic process GO:0010604 394 0.325
modification dependent macromolecule catabolic process GO:0043632 203 0.305
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 40 0.295
nitrogen compound transport GO:0071705 212 0.294
cellular macromolecule catabolic process GO:0044265 363 0.294
regulation of dna templated transcription initiation GO:2000142 19 0.283
cellular protein catabolic process GO:0044257 213 0.277
phosphorylation GO:0016310 291 0.276
positive regulation of rna biosynthetic process GO:1902680 286 0.269
protein localization to nucleus GO:0034504 74 0.259
transcription of nuclear large rrna transcript from rna polymerase i promoter GO:0042790 19 0.242
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 40 0.232
positive regulation of rna metabolic process GO:0051254 294 0.217
positive regulation of gene expression GO:0010628 321 0.209
organophosphate metabolic process GO:0019637 597 0.208
nucleocytoplasmic transport GO:0006913 163 0.204
rrna catabolic process GO:0016075 31 0.202
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 30 0.201
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.197
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 19 0.193
nuclear import GO:0051170 57 0.188
single organism nuclear import GO:1902593 56 0.185
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.184
regulation of mitosis GO:0007088 65 0.182
er associated ubiquitin dependent protein catabolic process GO:0030433 46 0.181
regulation of dna templated transcription elongation GO:0032784 44 0.177
rrna metabolic process GO:0016072 244 0.173
positive regulation of biosynthetic process GO:0009891 336 0.172
positive regulation of nucleic acid templated transcription GO:1903508 286 0.165
positive regulation of dna templated transcription elongation GO:0032786 42 0.161
ribonucleotide metabolic process GO:0009259 377 0.157
negative regulation of transcription dna templated GO:0045892 258 0.156
organonitrogen compound catabolic process GO:1901565 404 0.147
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 11 0.142
nucleoside monophosphate metabolic process GO:0009123 267 0.141
protein targeting to nucleus GO:0044744 57 0.141
transcription elongation from rna polymerase ii promoter GO:0006368 81 0.140
dna templated transcription elongation GO:0006354 91 0.139
regulation of protein metabolic process GO:0051246 237 0.139
regulation of protein modification process GO:0031399 110 0.138
aromatic compound catabolic process GO:0019439 491 0.127
microtubule cytoskeleton organization GO:0000226 109 0.127
transcription initiation from rna polymerase ii promoter GO:0006367 55 0.127
nucleoside phosphate metabolic process GO:0006753 458 0.125
positive regulation of dna templated transcription initiation GO:2000144 13 0.121
mitochondrion organization GO:0007005 261 0.121
protein complex localization GO:0031503 32 0.121
purine nucleoside monophosphate metabolic process GO:0009126 262 0.119
ribosome biogenesis GO:0042254 335 0.118
glycosyl compound catabolic process GO:1901658 335 0.116
protein modification by small protein conjugation GO:0032446 144 0.113
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.112
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.109
nucleotide metabolic process GO:0009117 453 0.107
ribonucleoside metabolic process GO:0009119 389 0.107
regulation of exit from mitosis GO:0007096 29 0.107
nucleoside catabolic process GO:0009164 335 0.106
regulation of protein serine threonine kinase activity GO:0071900 41 0.106
purine nucleotide metabolic process GO:0006163 376 0.105
maintenance of location GO:0051235 66 0.104
ribonucleoside monophosphate metabolic process GO:0009161 265 0.101
positive regulation of phosphate metabolic process GO:0045937 147 0.100
nuclear transport GO:0051169 165 0.100
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 38 0.098
purine ribonucleotide metabolic process GO:0009150 372 0.097
gene silencing GO:0016458 151 0.096
protein modification by small protein conjugation or removal GO:0070647 172 0.094
microtubule based process GO:0007017 117 0.093
protein import into nucleus GO:0006606 55 0.093
regulation of molecular function GO:0065009 320 0.093
nucleotide excision repair GO:0006289 50 0.088
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.088
regulation of cellular component biogenesis GO:0044087 112 0.087
regulation of protein phosphorylation GO:0001932 75 0.086
mitotic cell cycle process GO:1903047 294 0.086
negative regulation of rna metabolic process GO:0051253 262 0.086
purine nucleoside catabolic process GO:0006152 330 0.086
nucleobase containing compound catabolic process GO:0034655 479 0.084
dna templated transcription initiation GO:0006352 71 0.084
peptide transport GO:0015833 14 0.083
regulation of catalytic activity GO:0050790 307 0.082
regulation of protein ubiquitination GO:0031396 20 0.081
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.081
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.079
regulation of cellular protein metabolic process GO:0032268 232 0.077
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 13 0.076
negative regulation of molecular function GO:0044092 68 0.076
cellular response to nutrient levels GO:0031669 144 0.074
purine ribonucleoside metabolic process GO:0046128 380 0.073
autophagy GO:0006914 106 0.072
purine nucleoside triphosphate metabolic process GO:0009144 356 0.071
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.071
chromatin modification GO:0016568 200 0.070
regulation of phosphate metabolic process GO:0019220 230 0.070
ribonucleoside triphosphate metabolic process GO:0009199 356 0.070
single organism developmental process GO:0044767 258 0.069
Worm
cellular nitrogen compound catabolic process GO:0044270 494 0.068
ribonucleoside catabolic process GO:0042454 332 0.068
mitotic nuclear division GO:0007067 131 0.068
positive regulation of transcription dna templated GO:0045893 286 0.068
heterocycle catabolic process GO:0046700 494 0.067
ribose phosphate metabolic process GO:0019693 384 0.066
regulation of mitotic cell cycle GO:0007346 107 0.065
negative regulation of cellular metabolic process GO:0031324 407 0.065
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 35 0.065
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 36 0.064
regulation of cellular protein catabolic process GO:1903362 36 0.063
nucleoside triphosphate catabolic process GO:0009143 329 0.063
carbohydrate derivative catabolic process GO:1901136 339 0.061
dna templated transcriptional preinitiation complex assembly GO:0070897 51 0.060
atp catabolic process GO:0006200 224 0.059
regulation of mitotic sister chromatid segregation GO:0033047 30 0.057
purine nucleoside metabolic process GO:0042278 380 0.057
positive regulation of cellular component organization GO:0051130 116 0.055
amide transport GO:0042886 22 0.055
regulation of proteasomal protein catabolic process GO:0061136 34 0.054
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.053
regulation of protein complex assembly GO:0043254 77 0.052
purine nucleotide catabolic process GO:0006195 328 0.051
negative regulation of gene expression GO:0010629 312 0.051
protein import GO:0017038 122 0.050
positive regulation of protein complex assembly GO:0031334 39 0.049
cytoplasm associated proteasomal ubiquitin dependent protein catabolic process GO:0071629 5 0.047
secretion by cell GO:0032940 50 0.047
purine ribonucleotide catabolic process GO:0009154 327 0.046
dna repair GO:0006281 236 0.046
protein deubiquitination GO:0016579 17 0.046
nucleoside metabolic process GO:0009116 394 0.045
negative regulation of macromolecule metabolic process GO:0010605 375 0.045
purine nucleoside triphosphate catabolic process GO:0009146 329 0.044
regulation of phosphorus metabolic process GO:0051174 230 0.044
cellular ion homeostasis GO:0006873 112 0.044
regulation of catabolic process GO:0009894 199 0.044
organophosphate catabolic process GO:0046434 338 0.044
regulation of gene expression epigenetic GO:0040029 147 0.044
cullin deneddylation GO:0010388 6 0.043
regulation of cellular component organization GO:0051128 334 0.043
regulation of biological quality GO:0065008 391 0.042
regulation of nuclear division GO:0051783 103 0.042
positive regulation of catalytic activity GO:0043085 178 0.042
protein dna complex subunit organization GO:0071824 153 0.042
establishment of protein localization to organelle GO:0072594 278 0.041
positive regulation of molecular function GO:0044093 185 0.041
response to topologically incorrect protein GO:0035966 38 0.041
purine ribonucleoside catabolic process GO:0046130 330 0.041
regulation of protein catabolic process GO:0042176 40 0.040
positive regulation of protein modification process GO:0031401 49 0.040
glycosyl compound metabolic process GO:1901657 398 0.040
organonitrogen compound biosynthetic process GO:1901566 314 0.039
positive regulation of phosphorylation GO:0042327 33 0.039
purine containing compound metabolic process GO:0072521 400 0.039
positive regulation of cellular component biogenesis GO:0044089 45 0.038
spindle organization GO:0007051 37 0.038
mitotic spindle elongation GO:0000022 14 0.038
negative regulation of rna biosynthetic process GO:1902679 260 0.038
nucleobase containing small molecule metabolic process GO:0055086 491 0.037
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.037
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.037
positive regulation of protein metabolic process GO:0051247 93 0.037
regulation of phosphorylation GO:0042325 86 0.037
protein localization to organelle GO:0033365 337 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.036
nucleoside phosphate catabolic process GO:1901292 331 0.036
positive regulation of protein phosphorylation GO:0001934 28 0.036
mitotic cell cycle GO:0000278 306 0.036
mrna transport GO:0051028 60 0.036
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 13 0.035
protein dna complex assembly GO:0065004 105 0.035
negative regulation of biosynthetic process GO:0009890 312 0.034
regulation of protein modification by small protein conjugation or removal GO:1903320 29 0.033
maintenance of protein location in cell GO:0032507 50 0.033
purine ribonucleotide biosynthetic process GO:0009152 39 0.033
ribonucleoside monophosphate catabolic process GO:0009158 224 0.033
protein ubiquitination GO:0016567 118 0.033
positive regulation of catabolic process GO:0009896 135 0.033
maintenance of dna repeat elements GO:0043570 20 0.032
positive regulation of protein kinase activity GO:0045860 22 0.032
generation of precursor metabolites and energy GO:0006091 147 0.032
chromatin silencing at telomere GO:0006348 84 0.032
nucleoside monophosphate catabolic process GO:0009125 224 0.032
regulation of proteolysis GO:0030162 44 0.032
protein phosphorylation GO:0006468 197 0.032
misfolded or incompletely synthesized protein catabolic process GO:0006515 21 0.032
purine containing compound catabolic process GO:0072523 332 0.032
negative regulation of cellular component organization GO:0051129 109 0.032
chromatin remodeling GO:0006338 80 0.031
transcription from rna polymerase i promoter GO:0006360 63 0.031
negative regulation of gene expression epigenetic GO:0045814 147 0.031
negative regulation of nucleic acid templated transcription GO:1903507 260 0.031
response to nutrient levels GO:0031667 150 0.030
cellular response to extracellular stimulus GO:0031668 150 0.030
translational initiation GO:0006413 56 0.030
purine nucleoside monophosphate catabolic process GO:0009128 224 0.029
rna transport GO:0050658 92 0.029
ascospore wall assembly GO:0030476 52 0.029
response to extracellular stimulus GO:0009991 156 0.028
regulation of kinase activity GO:0043549 71 0.028
gene silencing by rna GO:0031047 3 0.028
histone modification GO:0016570 119 0.028
regulation of cellular catabolic process GO:0031329 195 0.028
cell division GO:0051301 205 0.028
maintenance of protein location GO:0045185 53 0.027
translation GO:0006412 230 0.027
maintenance of location in cell GO:0051651 58 0.027
ascospore wall biogenesis GO:0070591 52 0.027
ribonucleotide biosynthetic process GO:0009260 44 0.027
negative regulation of phosphorylation GO:0042326 28 0.027
non recombinational repair GO:0000726 33 0.027
organelle localization GO:0051640 128 0.026
reproductive process GO:0022414 248 0.026
positive regulation of kinase activity GO:0033674 24 0.026
protein targeting GO:0006605 272 0.026
mitotic sister chromatid separation GO:0051306 26 0.026
regulation of chromosome organization GO:0033044 66 0.025
nucleotide catabolic process GO:0009166 330 0.025
ribose phosphate biosynthetic process GO:0046390 50 0.025
negative regulation of mapk cascade GO:0043409 11 0.025
developmental process GO:0032502 261 0.025
Worm
ribosome associated ubiquitin dependent protein catabolic process GO:1990116 7 0.025
rna export from nucleus GO:0006405 88 0.025
proteasomal ubiquitin independent protein catabolic process GO:0010499 14 0.024
cellular response to starvation GO:0009267 90 0.024
protein modification by small protein removal GO:0070646 29 0.024
regulation of hydrolase activity GO:0051336 133 0.024
positive regulation of cellular response to drug GO:2001040 3 0.024
ribonucleoside triphosphate catabolic process GO:0009203 327 0.024
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.024
regulation of cell cycle process GO:0010564 150 0.023
secretion GO:0046903 50 0.023
positive regulation of phosphorus metabolic process GO:0010562 147 0.023
protein maturation GO:0051604 76 0.023
positive regulation of cellular protein metabolic process GO:0032270 89 0.023
cellular protein complex disassembly GO:0043624 42 0.023
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.023
posttranscriptional regulation of gene expression GO:0010608 115 0.022
cellular response to topologically incorrect protein GO:0035967 32 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.022
mrna metabolic process GO:0016071 269 0.022
protein transport GO:0015031 345 0.022
macroautophagy GO:0016236 55 0.022
ribonucleotide catabolic process GO:0009261 327 0.022
response to misfolded protein GO:0051788 11 0.022
histone deubiquitination GO:0016578 6 0.021
positive regulation of transferase activity GO:0051347 28 0.021
covalent chromatin modification GO:0016569 119 0.021
ncrna catabolic process GO:0034661 33 0.021
negative regulation of protein metabolic process GO:0051248 85 0.020
carbohydrate derivative metabolic process GO:1901135 549 0.020
glucan metabolic process GO:0044042 44 0.020
ncrna processing GO:0034470 330 0.020
regulation of cell cycle GO:0051726 195 0.020
cell cycle phase transition GO:0044770 144 0.020
er to golgi vesicle mediated transport GO:0006888 86 0.020
positive regulation of protein serine threonine kinase activity GO:0071902 7 0.020
negative regulation of catalytic activity GO:0043086 60 0.019
negative regulation of cellular protein catabolic process GO:1903363 27 0.019
regulation of protein localization to nucleus GO:1900180 16 0.019
nucleoside triphosphate metabolic process GO:0009141 364 0.019
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 27 0.019
mitotic spindle organization GO:0007052 30 0.019
negative regulation of proteasomal protein catabolic process GO:1901799 25 0.019
negative regulation of protein dephosphorylation GO:0035308 2 0.019
mismatch repair GO:0006298 14 0.019
establishment of protein localization to membrane GO:0090150 99 0.019
regulation of chromosome segregation GO:0051983 44 0.019
response to organic cyclic compound GO:0014070 1 0.018
regulation of response to dna damage stimulus GO:2001020 17 0.018
chromatin organization GO:0006325 242 0.018
rrna processing GO:0006364 227 0.018
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 19 0.018
programmed cell death GO:0012501 30 0.018
Worm
nonfunctional rrna decay GO:0070651 12 0.018
regulation of transport GO:0051049 85 0.018
energy reserve metabolic process GO:0006112 32 0.018
single organism catabolic process GO:0044712 619 0.018
regulation of cellular response to drug GO:2001038 3 0.018
carbohydrate derivative biosynthetic process GO:1901137 181 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.017
mrna export from nucleus GO:0006406 60 0.017
cellular developmental process GO:0048869 191 0.017
regulation of localization GO:0032879 127 0.017
establishment of protein localization GO:0045184 367 0.017
double strand break repair GO:0006302 105 0.017
positive regulation of programmed cell death GO:0043068 3 0.017
positive regulation of cell growth GO:0030307 7 0.017
nuclear transcribed mrna catabolic process GO:0000956 89 0.017
metaphase anaphase transition of cell cycle GO:0044784 28 0.017
autophagic vacuole assembly GO:0000045 16 0.017
microtubule organizing center organization GO:0031023 33 0.016
negative regulation of intracellular signal transduction GO:1902532 27 0.016
regulation of cell division GO:0051302 113 0.016
protein processing GO:0016485 64 0.016
internal peptidyl lysine acetylation GO:0018393 52 0.016
rna catabolic process GO:0006401 118 0.016
cellular homeostasis GO:0019725 138 0.016
negative regulation of phosphate metabolic process GO:0045936 49 0.016
cell wall assembly GO:0070726 54 0.016
spindle pole body organization GO:0051300 33 0.016
rna localization GO:0006403 112 0.015
response to starvation GO:0042594 96 0.015
nucleoside phosphate biosynthetic process GO:1901293 80 0.015
endocytosis GO:0006897 90 0.015
mitotic cell cycle phase transition GO:0044772 141 0.015
positive regulation of hydrolase activity GO:0051345 112 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.015
regulation of cellular localization GO:0060341 50 0.015
negative regulation of protein modification process GO:0031400 37 0.014
glycogen metabolic process GO:0005977 30 0.014
cell death GO:0008219 30 0.014
Worm
nuclear export GO:0051168 124 0.014
double strand break repair via nonhomologous end joining GO:0006303 27 0.014
sexual reproduction GO:0019953 216 0.014
macromolecular complex disassembly GO:0032984 80 0.014
spore wall biogenesis GO:0070590 52 0.014
microtubule anchoring GO:0034453 25 0.014
iron sulfur cluster assembly GO:0016226 22 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
response to calcium ion GO:0051592 1 0.014
nuclear division GO:0000280 263 0.014
organelle fission GO:0048285 272 0.014
regulation of potassium ion concentration by positive regulation of transcription from rna polymerase ii promoter GO:0097301 1 0.014
chromosome organization involved in meiosis GO:0070192 32 0.013
positive regulation of apoptotic process GO:0043065 3 0.013
negative regulation of phosphorus metabolic process GO:0010563 49 0.013
chromosome segregation GO:0007059 159 0.013
regulation of mitochondrion organization GO:0010821 20 0.013
conjugation with cellular fusion GO:0000747 106 0.013
aging GO:0007568 71 0.013
Worm
regulation of transcription from rna polymerase i promoter GO:0006356 36 0.013
regulation of organelle organization GO:0033043 243 0.013
cytoskeleton organization GO:0007010 230 0.013
nuclear transcribed mrna poly a tail shortening GO:0000289 14 0.013
dna recombination GO:0006310 172 0.012
spindle elongation GO:0051231 14 0.012
positive regulation of cellular catabolic process GO:0031331 128 0.012
regulation of chromatin silencing GO:0031935 39 0.012
mrna catabolic process GO:0006402 93 0.012
regulation of mitotic cell cycle phase transition GO:1901990 68 0.012
cleavage involved in rrna processing GO:0000469 69 0.012
positive regulation of secretion GO:0051047 2 0.012
cell communication GO:0007154 345 0.012
regulation of mapk cascade GO:0043408 22 0.012
positive regulation of transcription by oleic acid GO:0061421 4 0.012
establishment of organelle localization GO:0051656 96 0.012
negative regulation of cell communication GO:0010648 33 0.012
positive regulation of protein localization to nucleus GO:1900182 7 0.012
response to temperature stimulus GO:0009266 74 0.012
polysaccharide metabolic process GO:0005976 60 0.012
negative regulation of proteolysis GO:0045861 33 0.011
purine containing compound biosynthetic process GO:0072522 53 0.011
vesicle mediated transport GO:0016192 335 0.011
mrna 3 end processing GO:0031124 54 0.011
positive regulation of protein catabolic process GO:0045732 9 0.011
negative regulation of exit from mitosis GO:0001100 16 0.011
detection of stimulus GO:0051606 4 0.011
sister chromatid segregation GO:0000819 93 0.011
cellular glucan metabolic process GO:0006073 44 0.011
protein acetylation GO:0006473 59 0.011
replicative cell aging GO:0001302 46 0.011
organelle inheritance GO:0048308 51 0.011
metal ion homeostasis GO:0055065 79 0.011
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 5 0.011
fungal type cell wall biogenesis GO:0009272 80 0.011
metallo sulfur cluster assembly GO:0031163 22 0.011
telomere maintenance via telomerase GO:0007004 21 0.010
organic cyclic compound catabolic process GO:1901361 499 0.010
osmosensory signaling pathway GO:0007231 22 0.010
mrna processing GO:0006397 185 0.010
positive regulation of intracellular protein transport GO:0090316 3 0.010
regulation of chromatin organization GO:1902275 23 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 6 0.010
cellular response to external stimulus GO:0071496 150 0.010
regulation of sister chromatid segregation GO:0033045 30 0.010
regulation of intracellular protein transport GO:0033157 13 0.010
fungal type cell wall assembly GO:0071940 53 0.010
regulation of mitotic sister chromatid separation GO:0010965 29 0.010
negative regulation of protein maturation GO:1903318 33 0.010
conjugation GO:0000746 107 0.010
cell differentiation GO:0030154 161 0.010

RPN2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012