Saccharomyces cerevisiae

20 known processes

YAK1 (YJL141C)

Yak1p

YAK1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.946
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.906
Human
positive regulation of transcription dna templated GO:0045893 286 0.880
Human
positive regulation of gene expression GO:0010628 321 0.863
Human
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.862
positive regulation of rna metabolic process GO:0051254 294 0.830
Human
regulation of response to stress GO:0080134 57 0.822
Mouse
negative regulation of rna metabolic process GO:0051253 262 0.818
Mouse
negative regulation of cellular biosynthetic process GO:0031327 312 0.817
positive regulation of rna biosynthetic process GO:1902680 286 0.802
Human
positive regulation of biosynthetic process GO:0009891 336 0.769
Human
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.740
Mouse
negative regulation of cellular metabolic process GO:0031324 407 0.723
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.712
Human
positive regulation of macromolecule metabolic process GO:0010604 394 0.691
Human Mouse
negative regulation of gene expression GO:0010629 312 0.684
Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.660
negative regulation of transcription dna templated GO:0045892 258 0.659
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.614
Human
positive regulation of nucleic acid templated transcription GO:1903508 286 0.582
Human
intracellular signal transduction GO:0035556 112 0.577
Mouse
multi organism process GO:0051704 233 0.574
developmental process GO:0032502 261 0.564
Human Zebrafish Mouse
regulation of response to stimulus GO:0048583 157 0.518
Mouse
negative regulation of macromolecule metabolic process GO:0010605 375 0.512
Mouse
cell division GO:0051301 205 0.476
cellular response to dna damage stimulus GO:0006974 287 0.476
Mouse
negative regulation of nucleic acid templated transcription GO:1903507 260 0.455
cellular response to chemical stimulus GO:0070887 315 0.450
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.440
regulation of organelle organization GO:0033043 243 0.440
negative regulation of rna biosynthetic process GO:1902679 260 0.434
response to chemical GO:0042221 390 0.421
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.403
multi organism reproductive process GO:0044703 216 0.393
cell communication GO:0007154 345 0.388
Mouse
mitotic cell cycle phase transition GO:0044772 141 0.370
organelle fission GO:0048285 272 0.360
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.346
Mouse
signaling GO:0023052 208 0.342
Mouse
single organism developmental process GO:0044767 258 0.336
Human Zebrafish Mouse
positive regulation of cellular biosynthetic process GO:0031328 336 0.335
Human
modification dependent macromolecule catabolic process GO:0043632 203 0.330
response to abiotic stimulus GO:0009628 159 0.325
cellular protein catabolic process GO:0044257 213 0.312
negative regulation of biosynthetic process GO:0009890 312 0.307
regulation of cell cycle process GO:0010564 150 0.297
single organism catabolic process GO:0044712 619 0.286
regulation of dna metabolic process GO:0051052 100 0.282
proteolysis GO:0006508 268 0.278
homeostatic process GO:0042592 227 0.278
positive regulation of growth GO:0045927 19 0.275
cellular homeostasis GO:0019725 138 0.275
meiotic nuclear division GO:0007126 163 0.269
ubiquitin dependent protein catabolic process GO:0006511 181 0.257
developmental process involved in reproduction GO:0003006 159 0.250
aging GO:0007568 71 0.248
cellular response to organic substance GO:0071310 159 0.224
growth GO:0040007 157 0.224
regulation of biological quality GO:0065008 391 0.223
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 51 0.223
signal transduction GO:0007165 208 0.216
Mouse
response to oxygen containing compound GO:1901700 61 0.212
response to extracellular stimulus GO:0009991 156 0.203
regulation of cell cycle GO:0051726 195 0.198
cellular response to oxidative stress GO:0034599 94 0.197
regulation of cellular component organization GO:0051128 334 0.190
response to starvation GO:0042594 96 0.190
positive regulation of response to stimulus GO:0048584 37 0.188
cell aging GO:0007569 70 0.182
protein phosphorylation GO:0006468 197 0.180
regulation of signaling GO:0023051 119 0.176
Mouse
regulation of signal transduction GO:0009966 114 0.173
Mouse
response to nutrient levels GO:0031667 150 0.172
cation transport GO:0006812 166 0.170
phosphorylation GO:0016310 291 0.169
oxoacid metabolic process GO:0043436 351 0.166
organic acid metabolic process GO:0006082 352 0.161
peptidyl amino acid modification GO:0018193 116 0.156
response to external stimulus GO:0009605 158 0.155
anatomical structure morphogenesis GO:0009653 160 0.153
Zebrafish Mouse
regulation of intracellular signal transduction GO:1902531 78 0.153
Mouse
microtubule cytoskeleton organization GO:0000226 109 0.150
mitotic cell cycle process GO:1903047 294 0.143
regulation of cellular protein catabolic process GO:1903362 36 0.143
positive regulation of sodium ion transport GO:0010765 1 0.140
metal ion homeostasis GO:0055065 79 0.139
ion transport GO:0006811 274 0.137
chromatin silencing GO:0006342 147 0.134
regulation of localization GO:0032879 127 0.133
cytokinesis GO:0000910 92 0.131
regulation of dna templated transcription in response to stress GO:0043620 51 0.129
sexual reproduction GO:0019953 216 0.118
regulation of catabolic process GO:0009894 199 0.117
response to oxidative stress GO:0006979 99 0.111
mitotic cytokinesis GO:0000281 58 0.109
reproductive process GO:0022414 248 0.107
regulation of molecular function GO:0065009 320 0.106
regulation of filamentous growth of a population of unicellular organisms GO:1900428 36 0.103
regulation of response to external stimulus GO:0032101 20 0.102
cell differentiation GO:0030154 161 0.102
Mouse
regulation of growth GO:0040008 50 0.102
anatomical structure formation involved in morphogenesis GO:0048646 136 0.100
Zebrafish Mouse
response to organic substance GO:0010033 182 0.097
negative regulation of response to stimulus GO:0048585 40 0.096
Mouse
chemical homeostasis GO:0048878 137 0.094
cellular response to nutrient levels GO:0031669 144 0.094
response to pheromone GO:0019236 92 0.093
ascospore formation GO:0030437 107 0.090
cellular ketone metabolic process GO:0042180 63 0.090
single organism signaling GO:0044700 208 0.090
Mouse
pseudohyphal growth GO:0007124 75 0.090
positive regulation of cell communication GO:0010647 28 0.089
regulation of anatomical structure size GO:0090066 50 0.086
modification dependent protein catabolic process GO:0019941 181 0.086
nuclear division GO:0000280 263 0.085
cytoskeleton organization GO:0007010 230 0.083
regulation of proteasomal protein catabolic process GO:0061136 34 0.082
regulation of cellular response to stress GO:0080135 50 0.082
Mouse
cellular developmental process GO:0048869 191 0.081
Mouse
regulation of cell communication GO:0010646 124 0.078
Mouse
regulation of cellular catabolic process GO:0031329 195 0.077
glycosyl compound metabolic process GO:1901657 398 0.077
regulation of protein metabolic process GO:0051246 237 0.076
Mouse
carboxylic acid metabolic process GO:0019752 338 0.075
cellular chemical homeostasis GO:0055082 123 0.075
cellular response to extracellular stimulus GO:0031668 150 0.075
positive regulation of cellular catabolic process GO:0031331 128 0.072
cell development GO:0048468 107 0.070
regulation of catalytic activity GO:0050790 307 0.069
metal ion transport GO:0030001 75 0.068
single organism reproductive process GO:0044702 159 0.066
organic cyclic compound catabolic process GO:1901361 499 0.066
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.064
sporulation resulting in formation of a cellular spore GO:0030435 129 0.064
cellular ion homeostasis GO:0006873 112 0.062
cellular metal ion homeostasis GO:0006875 78 0.060
cell cycle phase transition GO:0044770 144 0.060
positive regulation of catabolic process GO:0009896 135 0.060
cellular macromolecule catabolic process GO:0044265 363 0.058
regulation of proteolysis GO:0030162 44 0.058
regulation of cellular ketone metabolic process GO:0010565 42 0.058
macromolecular complex disassembly GO:0032984 80 0.057
positive regulation of cell cycle process GO:0090068 31 0.056
cell cycle checkpoint GO:0000075 82 0.056
protein catabolic process GO:0030163 221 0.055
cellular response to starvation GO:0009267 90 0.053
positive regulation of signaling GO:0023056 20 0.053
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 36 0.053
regulation of nuclear division GO:0051783 103 0.052
response to pheromone involved in conjugation with cellular fusion GO:0000749 74 0.049
chromatin modification GO:0016568 200 0.049
cellular component disassembly GO:0022411 86 0.049
regulation of transport GO:0051049 85 0.049
cation homeostasis GO:0055080 105 0.048
meiotic cell cycle GO:0051321 272 0.048
regulation of filamentous growth GO:0010570 38 0.048
reproduction of a single celled organism GO:0032505 191 0.048
cellular response to pheromone GO:0071444 88 0.048
microtubule based process GO:0007017 117 0.047
cellular response to oxygen containing compound GO:1901701 43 0.047
cellular response to external stimulus GO:0071496 150 0.046
filamentous growth GO:0030447 124 0.045
carbohydrate derivative metabolic process GO:1901135 549 0.045
regulation of protein catabolic process GO:0042176 40 0.045
regulation of lipid biosynthetic process GO:0046890 32 0.045
response to organic cyclic compound GO:0014070 1 0.044
dna repair GO:0006281 236 0.044
regulation of cellular component size GO:0032535 50 0.043
fatty acid metabolic process GO:0006631 51 0.042
invasive filamentous growth GO:0036267 65 0.042
vesicle mediated transport GO:0016192 335 0.040
proteasomal protein catabolic process GO:0010498 141 0.040
cellular cation homeostasis GO:0030003 100 0.040
monovalent inorganic cation homeostasis GO:0055067 32 0.039
negative regulation of mrna processing GO:0050686 2 0.039
Mouse
macromolecule catabolic process GO:0009057 383 0.039
ion homeostasis GO:0050801 118 0.039
aromatic compound catabolic process GO:0019439 491 0.038
reproductive process in single celled organism GO:0022413 145 0.037
carbohydrate metabolic process GO:0005975 252 0.037
chromatin organization GO:0006325 242 0.037
protein polymerization GO:0051258 51 0.037
positive regulation of filamentous growth of a population of unicellular organisms GO:1900430 18 0.036
cellular response to caloric restriction GO:0061433 2 0.036
lipid localization GO:0010876 60 0.036
cell growth GO:0016049 89 0.035
heterocycle catabolic process GO:0046700 494 0.035
sporulation GO:0043934 132 0.034
regulation of metal ion transport GO:0010959 2 0.034
protein complex assembly GO:0006461 302 0.034
single organism membrane organization GO:0044802 275 0.034
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.032
mitotic nuclear division GO:0007067 131 0.032
regulation of response to extracellular stimulus GO:0032104 20 0.032
hexose metabolic process GO:0019318 78 0.032
positive regulation of catalytic activity GO:0043085 178 0.032
polysaccharide metabolic process GO:0005976 60 0.031
cellular protein complex disassembly GO:0043624 42 0.031
negative regulation of cellular component organization GO:0051129 109 0.031
negative regulation of cellular hyperosmotic salinity response by negative regulation of transcription from rna polymerase ii promoter GO:1900464 2 0.031
negative regulation of gene expression epigenetic GO:0045814 147 0.031
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.031
regulation of cell size GO:0008361 30 0.031
carbohydrate biosynthetic process GO:0016051 82 0.030
regulation of microtubule based process GO:0032886 32 0.030
regulation of growth of unicellular organism as a thread of attached cells GO:0070784 31 0.030
regulation of cellular protein metabolic process GO:0032268 232 0.030
Mouse
gene silencing GO:0016458 151 0.029
meiotic cell cycle process GO:1903046 229 0.029
dna replication GO:0006260 147 0.029
regulation of sodium ion transport GO:0002028 1 0.029
ras protein signal transduction GO:0007265 29 0.029
nucleobase containing small molecule metabolic process GO:0055086 491 0.028
response to inorganic substance GO:0010035 47 0.028
transcription from rna polymerase iii promoter GO:0006383 40 0.028
anatomical structure development GO:0048856 160 0.028
Human Zebrafish Mouse
positive regulation of lipid catabolic process GO:0050996 4 0.028
response to temperature stimulus GO:0009266 74 0.028
response to heat GO:0009408 69 0.028
response to uv GO:0009411 4 0.028
nitrogen compound transport GO:0071705 212 0.028
cellular nitrogen compound catabolic process GO:0044270 494 0.028
monocarboxylic acid metabolic process GO:0032787 122 0.028
programmed cell death GO:0012501 30 0.027
endomembrane system organization GO:0010256 74 0.027
positive regulation of molecular function GO:0044093 185 0.026
lipid metabolic process GO:0006629 269 0.026
organic hydroxy compound biosynthetic process GO:1901617 81 0.025
g1 s transition of mitotic cell cycle GO:0000082 64 0.025
regulation of protein localization GO:0032880 62 0.025
rna catabolic process GO:0006401 118 0.024
protein processing GO:0016485 64 0.024
cell cycle g1 s phase transition GO:0044843 64 0.024
regulation of mitotic cell cycle phase transition GO:1901990 68 0.024
regulation of cellular component biogenesis GO:0044087 112 0.024
protein complex disassembly GO:0043241 70 0.024
mitotic cell cycle GO:0000278 306 0.023
positive regulation of cellular component organization GO:0051130 116 0.023
chromatin silencing at telomere GO:0006348 84 0.022
monovalent inorganic cation transport GO:0015672 78 0.022
positive regulation of programmed cell death GO:0043068 3 0.022
cellular response to abiotic stimulus GO:0071214 62 0.022
filamentous growth of a population of unicellular organisms GO:0044182 109 0.021
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 9 0.021
regulation of cell division GO:0051302 113 0.021
response to organonitrogen compound GO:0010243 18 0.021
positive regulation of apoptotic process GO:0043065 3 0.021
regulation of meiosis GO:0040020 42 0.021
lipid biosynthetic process GO:0008610 170 0.020
cytokinetic process GO:0032506 78 0.020
chronological cell aging GO:0001300 28 0.020
conjugation GO:0000746 107 0.020
membrane lipid biosynthetic process GO:0046467 54 0.020
nucleobase containing compound catabolic process GO:0034655 479 0.020
negative regulation of catabolic process GO:0009895 43 0.020
cytoskeleton dependent cytokinesis GO:0061640 65 0.020
sodium ion transport GO:0006814 9 0.020
oxidation reduction process GO:0055114 353 0.019
positive regulation of cellular protein metabolic process GO:0032270 89 0.019
Mouse
cellular response to heat GO:0034605 53 0.019
glucose metabolic process GO:0006006 65 0.019
conjugation with cellular fusion GO:0000747 106 0.019
nuclear export GO:0051168 124 0.018
purine nucleoside catabolic process GO:0006152 330 0.018
histone modification GO:0016570 119 0.018
positive regulation of cell cycle GO:0045787 32 0.018
ribonucleotide metabolic process GO:0009259 377 0.018
cellular response to nutrient GO:0031670 50 0.018
response to endogenous stimulus GO:0009719 26 0.018
regulation of transcription from rna polymerase ii promoter in response to uv induced dna damage GO:0010767 1 0.017
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.017
cellular response to osmotic stress GO:0071470 50 0.017
regulation of cellular hyperosmotic salinity response GO:1900069 2 0.016
negative regulation of dna metabolic process GO:0051053 36 0.016
protein maturation GO:0051604 76 0.016
regulation of replicative cell aging by regulation of transcription from rna polymerase ii promoter in response to caloric restriction GO:0061434 2 0.016
negative regulation of cell communication GO:0010648 33 0.016
Mouse
positive regulation of cell death GO:0010942 3 0.016
positive regulation of response to drug GO:2001025 3 0.016
cellular lipid metabolic process GO:0044255 229 0.016
negative regulation of organelle organization GO:0010639 103 0.016
carboxylic acid biosynthetic process GO:0046394 152 0.016
replicative cell aging GO:0001302 46 0.015
positive regulation of filamentous growth of a population of unicellular organisms in response to starvation GO:1900436 4 0.015
ribose phosphate metabolic process GO:0019693 384 0.015
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 22 0.015
regulation of ion transport GO:0043269 16 0.015
cellular monovalent inorganic cation homeostasis GO:0030004 27 0.015
response to osmotic stress GO:0006970 83 0.015
peptidyl serine phosphorylation GO:0018105 7 0.015
Mouse Rat
ribonucleoside metabolic process GO:0009119 389 0.015
meiosis i GO:0007127 92 0.015
sex determination GO:0007530 32 0.015
carbohydrate transport GO:0008643 33 0.015
organophosphate ester transport GO:0015748 45 0.015
fatty acid beta oxidation GO:0006635 12 0.015
positive regulation of organelle organization GO:0010638 85 0.015
sexual sporulation GO:0034293 113 0.015
positive regulation of signal transduction GO:0009967 20 0.015
membrane organization GO:0061024 276 0.014
dna dependent dna replication GO:0006261 115 0.014
regulation of response to drug GO:2001023 3 0.014
regulation of developmental process GO:0050793 30 0.014
response to nutrient GO:0007584 52 0.014
regulation of fatty acid beta oxidation GO:0031998 3 0.014
cell death GO:0008219 30 0.014
cellular amine metabolic process GO:0044106 51 0.014
negative regulation of cell cycle GO:0045786 91 0.014
organophosphate metabolic process GO:0019637 597 0.013
establishment of protein localization GO:0045184 367 0.013
cellular response to zinc ion starvation GO:0034224 3 0.013
organonitrogen compound catabolic process GO:1901565 404 0.013
golgi vesicle transport GO:0048193 188 0.013
regulation of gene expression epigenetic GO:0040029 147 0.013
endocytosis GO:0006897 90 0.013
regulation of translation GO:0006417 89 0.013
regulation of dna replication GO:0006275 51 0.013
negative regulation of cellular hyperosmotic salinity response GO:1900070 2 0.013
negative regulation of binding GO:0051100 4 0.013
carbon catabolite regulation of transcription GO:0045990 39 0.012
transcription from rna polymerase i promoter GO:0006360 63 0.012
regulation of lipid catabolic process GO:0050994 4 0.012
cell wall biogenesis GO:0042546 93 0.012
purine nucleotide catabolic process GO:0006195 328 0.012
regulation of lipid metabolic process GO:0019216 45 0.012
nucleoside phosphate metabolic process GO:0006753 458 0.012
cellular component macromolecule biosynthetic process GO:0070589 24 0.012
negative regulation of cell cycle process GO:0010948 86 0.012
positive regulation of response to external stimulus GO:0032103 12 0.012
protein depolymerization GO:0051261 21 0.012
regulation of response to salt stress GO:1901000 2 0.011
cytokinetic cell separation GO:0000920 21 0.011
peptidyl serine modification GO:0018209 7 0.011
Mouse Rat
regulation of anion transport GO:0044070 12 0.011
dna recombination GO:0006310 172 0.011
regulation of invasive growth in response to glucose limitation GO:2000217 19 0.011
regulation of cellular amine metabolic process GO:0033238 21 0.011
negative regulation of mrna splicing via spliceosome GO:0048025 1 0.011
Mouse
sphingolipid biosynthetic process GO:0030148 29 0.011
mitotic sister chromatid segregation GO:0000070 85 0.011
filamentous growth of a population of unicellular organisms in response to starvation GO:0036170 5 0.011
organic acid biosynthetic process GO:0016053 152 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 30 0.011
carbohydrate derivative catabolic process GO:1901136 339 0.011
regulation of dna dependent dna replication GO:0090329 37 0.011
positive regulation of cytokinesis GO:0032467 2 0.011
mitotic cytokinetic process GO:1902410 45 0.010
purine nucleotide metabolic process GO:0006163 376 0.010
positive regulation of fatty acid beta oxidation GO:0032000 3 0.010
cellular response to salt stress GO:0071472 19 0.010
apoptotic process GO:0006915 30 0.010
cellular polysaccharide metabolic process GO:0044264 55 0.010

YAK1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013
Human
benign neonatal seizures DOID:14264 0 0.011
Human
epilepsy syndrome DOID:1826 0 0.011
Human
central nervous system disease DOID:331 0 0.011
Human
brain disease DOID:936 0 0.011
Human
electroclinical syndrome DOID:0050701 0 0.011
Human
neonatal period electroclinical syndrome DOID:0050702 0 0.011
Human
nervous system disease DOID:863 0 0.011
Human