Saccharomyces cerevisiae

58 known processes

DEF1 (YKL054C)

Def1p

(Aliases: VID31)

DEF1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna metabolic process GO:0016071 269 0.976
rna catabolic process GO:0006401 118 0.970
nuclear transcribed mrna catabolic process GO:0000956 89 0.941
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 44 0.930
mrna catabolic process GO:0006402 93 0.808
negative regulation of gene expression epigenetic GO:0045814 147 0.796
dna repair GO:0006281 236 0.727
mrna 3 end processing GO:0031124 54 0.686
mitotic cell cycle GO:0000278 306 0.636
aromatic compound catabolic process GO:0019439 491 0.635
organic cyclic compound catabolic process GO:1901361 499 0.631
mrna processing GO:0006397 185 0.614
chromatin silencing GO:0006342 147 0.583
rna 3 end processing GO:0031123 88 0.576
dna recombination GO:0006310 172 0.549
regulation of protein metabolic process GO:0051246 237 0.539
regulation of translation GO:0006417 89 0.515
translation GO:0006412 230 0.473
positive regulation of gene expression GO:0010628 321 0.472
heterocycle catabolic process GO:0046700 494 0.410
regulation of cellular protein metabolic process GO:0032268 232 0.385
posttranscriptional regulation of gene expression GO:0010608 115 0.367
negative regulation of gene expression GO:0010629 312 0.364
transcription elongation from rna polymerase ii promoter GO:0006368 81 0.361
meiotic cell cycle GO:0051321 272 0.361
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.343
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.341
positive regulation of biosynthetic process GO:0009891 336 0.325
cellular nitrogen compound catabolic process GO:0044270 494 0.320
regulation of gene expression epigenetic GO:0040029 147 0.302
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.281
nucleobase containing compound catabolic process GO:0034655 479 0.275
cell cycle phase transition GO:0044770 144 0.255
positive regulation of nucleic acid templated transcription GO:1903508 286 0.251
translational initiation GO:0006413 56 0.237
dna templated transcription elongation GO:0006354 91 0.235
negative regulation of protein metabolic process GO:0051248 85 0.230
negative regulation of rna metabolic process GO:0051253 262 0.226
cellular macromolecule catabolic process GO:0044265 363 0.226
cytoskeleton organization GO:0007010 230 0.221
gene silencing GO:0016458 151 0.214
replicative cell aging GO:0001302 46 0.209
regulation of dna templated transcription elongation GO:0032784 44 0.208
chromatin modification GO:0016568 200 0.205
organelle assembly GO:0070925 118 0.191
mitochondrion organization GO:0007005 261 0.183
ribonucleoprotein complex assembly GO:0022618 143 0.174
macromolecule catabolic process GO:0009057 383 0.173
positive regulation of macromolecule metabolic process GO:0010604 394 0.165
negative regulation of biosynthetic process GO:0009890 312 0.161
negative regulation of cellular biosynthetic process GO:0031327 312 0.159
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.158
regulation of chromatin silencing GO:0031935 39 0.158
meiotic nuclear division GO:0007126 163 0.157
sulfur compound metabolic process GO:0006790 95 0.155
chromatin organization GO:0006325 242 0.154
organelle localization GO:0051640 128 0.153
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 38 0.151
single organism developmental process GO:0044767 258 0.146
positive regulation of cellular component organization GO:0051130 116 0.145
carboxylic acid biosynthetic process GO:0046394 152 0.144
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.138
positive regulation of cellular component biogenesis GO:0044089 45 0.137
positive regulation of transcription dna templated GO:0045893 286 0.135
regulation of cellular catabolic process GO:0031329 195 0.132
organonitrogen compound biosynthetic process GO:1901566 314 0.131
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 40 0.131
ribonucleoprotein complex subunit organization GO:0071826 152 0.127
negative regulation of macromolecule metabolic process GO:0010605 375 0.120
positive regulation of dna templated transcription elongation GO:0032786 42 0.116
negative regulation of cellular protein metabolic process GO:0032269 85 0.116
negative regulation of translation GO:0017148 18 0.113
positive regulation of cellular biosynthetic process GO:0031328 336 0.112
single organism reproductive process GO:0044702 159 0.105
reproductive process GO:0022414 248 0.104
cellular response to dna damage stimulus GO:0006974 287 0.100
positive regulation of gene expression epigenetic GO:0045815 25 0.100
negative regulation of cellular metabolic process GO:0031324 407 0.096
mitotic cell cycle phase transition GO:0044772 141 0.095
aging GO:0007568 71 0.090
anatomical structure formation involved in morphogenesis GO:0048646 136 0.089
developmental process involved in reproduction GO:0003006 159 0.089
sporulation resulting in formation of a cellular spore GO:0030435 129 0.087
mitotic cell cycle process GO:1903047 294 0.087
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.085
regulation of cell cycle phase transition GO:1901987 70 0.081
golgi vesicle transport GO:0048193 188 0.077
negative regulation of gene silencing GO:0060969 27 0.077
anatomical structure morphogenesis GO:0009653 160 0.076
positive regulation of catabolic process GO:0009896 135 0.075
regulation of mitotic cell cycle phase transition GO:1901990 68 0.075
protein complex biogenesis GO:0070271 314 0.075
mitotic cell cycle checkpoint GO:0007093 56 0.072
positive regulation of organelle organization GO:0010638 85 0.072
purine containing compound metabolic process GO:0072521 400 0.072
positive regulation of rna biosynthetic process GO:1902680 286 0.069
meiotic cell cycle process GO:1903046 229 0.068
carboxylic acid metabolic process GO:0019752 338 0.065
negative regulation of chromatin silencing GO:0031936 25 0.064
regulation of molecular function GO:0065009 320 0.063
response to heat GO:0009408 69 0.062
reproductive process in single celled organism GO:0022413 145 0.060
anatomical structure development GO:0048856 160 0.059
maintenance of location in cell GO:0051651 58 0.059
regulation of catabolic process GO:0009894 199 0.059
regulation of dna metabolic process GO:0051052 100 0.058
protein modification by small protein conjugation or removal GO:0070647 172 0.058
organic acid biosynthetic process GO:0016053 152 0.057
vesicle mediated transport GO:0016192 335 0.057
reproduction of a single celled organism GO:0032505 191 0.057
nuclear division GO:0000280 263 0.056
sporulation GO:0043934 132 0.055
mitochondrion localization GO:0051646 29 0.055
negative regulation of mitotic cell cycle GO:0045930 63 0.054
positive regulation of rna metabolic process GO:0051254 294 0.054
dna replication GO:0006260 147 0.054
cellular response to chemical stimulus GO:0070887 315 0.053
sexual reproduction GO:0019953 216 0.052
negative regulation of transcription dna templated GO:0045892 258 0.052
ribonucleotide metabolic process GO:0009259 377 0.050
chromatin remodeling GO:0006338 80 0.049
stress granule assembly GO:0034063 8 0.046
organic acid metabolic process GO:0006082 352 0.046
positive regulation of molecular function GO:0044093 185 0.046
macromolecular complex disassembly GO:0032984 80 0.045
ribosomal small subunit biogenesis GO:0042274 124 0.044
reciprocal meiotic recombination GO:0007131 54 0.044
protein processing GO:0016485 64 0.043
response to temperature stimulus GO:0009266 74 0.043
single organism catabolic process GO:0044712 619 0.043
lipid modification GO:0030258 37 0.041
organophosphate metabolic process GO:0019637 597 0.041
rna localization GO:0006403 112 0.040
oxoacid metabolic process GO:0043436 351 0.039
protein maturation GO:0051604 76 0.039
cellular protein complex assembly GO:0043623 209 0.038
single organism cellular localization GO:1902580 375 0.036
negative regulation of cell cycle phase transition GO:1901988 59 0.035
protein transport GO:0015031 345 0.034
response to chemical GO:0042221 390 0.034
developmental process GO:0032502 261 0.034
homeostatic process GO:0042592 227 0.034
regulation of biological quality GO:0065008 391 0.034
g1 s transition of mitotic cell cycle GO:0000082 64 0.032
response to organic substance GO:0010033 182 0.032
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.031
sulfur compound biosynthetic process GO:0044272 53 0.031
positive regulation of protein metabolic process GO:0051247 93 0.031
establishment of organelle localization GO:0051656 96 0.031
cytokinetic process GO:0032506 78 0.031
protein targeting GO:0006605 272 0.030
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.030
response to oxidative stress GO:0006979 99 0.030
organophosphate biosynthetic process GO:0090407 182 0.029
nuclear transcribed mrna poly a tail shortening GO:0000289 14 0.029
double strand break repair GO:0006302 105 0.029
regulation of catalytic activity GO:0050790 307 0.028
protein complex assembly GO:0006461 302 0.028
cell cycle g1 s phase transition GO:0044843 64 0.028
multi organism process GO:0051704 233 0.028
cellular response to organic substance GO:0071310 159 0.027
cellular homeostasis GO:0019725 138 0.027
mitotic spindle organization GO:0007052 30 0.027
negative regulation of translational initiation GO:0045947 4 0.026
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.026
cell differentiation GO:0030154 161 0.024
regulation of gene silencing GO:0060968 41 0.024
negative regulation of rna biosynthetic process GO:1902679 260 0.024
cellular lipid metabolic process GO:0044255 229 0.024
small molecule biosynthetic process GO:0044283 258 0.023
cell aging GO:0007569 70 0.023
positive regulation of cellular protein metabolic process GO:0032270 89 0.023
ascospore formation GO:0030437 107 0.022
regulation of cell cycle GO:0051726 195 0.020
trna processing GO:0008033 101 0.020
regulation of organelle organization GO:0033043 243 0.020
protein complex disassembly GO:0043241 70 0.020
proteasomal protein catabolic process GO:0010498 141 0.020
ribonucleotide catabolic process GO:0009261 327 0.020
regulation of mitotic cell cycle GO:0007346 107 0.019
protein alkylation GO:0008213 48 0.019
positive regulation of dna metabolic process GO:0051054 26 0.019
ribose phosphate metabolic process GO:0019693 384 0.018
cell cycle checkpoint GO:0000075 82 0.018
regulation of cellular amino acid metabolic process GO:0006521 16 0.018
cell development GO:0048468 107 0.018
sexual sporulation GO:0034293 113 0.017
purine nucleotide metabolic process GO:0006163 376 0.017
positive regulation of cell cycle GO:0045787 32 0.017
positive regulation of hydrolase activity GO:0051345 112 0.017
histone methylation GO:0016571 28 0.017
peroxisome organization GO:0007031 68 0.017
mating type determination GO:0007531 32 0.017
positive regulation of cellular catabolic process GO:0031331 128 0.016
carbohydrate derivative catabolic process GO:1901136 339 0.016
protein modification by small protein removal GO:0070646 29 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.016
cytoskeleton dependent cytokinesis GO:0061640 65 0.015
negative regulation of nucleic acid templated transcription GO:1903507 260 0.015
protein methylation GO:0006479 48 0.015
cellular modified amino acid metabolic process GO:0006575 51 0.015
response to salt stress GO:0009651 34 0.015
response to inorganic substance GO:0010035 47 0.015
mitotic nuclear division GO:0007067 131 0.015
response to uv GO:0009411 4 0.015
dna templated transcription initiation GO:0006352 71 0.015
protein modification by small protein conjugation GO:0032446 144 0.015
intracellular mrna localization GO:0008298 23 0.015
negative regulation of cell cycle GO:0045786 91 0.015
regulation of cellular component organization GO:0051128 334 0.015
response to abiotic stimulus GO:0009628 159 0.014
regulation of protein complex assembly GO:0043254 77 0.014
g2 m transition of mitotic cell cycle GO:0000086 38 0.014
positive regulation of cell cycle process GO:0090068 31 0.014
organophosphate catabolic process GO:0046434 338 0.014
cofactor biosynthetic process GO:0051188 80 0.014
cellular response to oxidative stress GO:0034599 94 0.013
multi organism reproductive process GO:0044703 216 0.013
energy derivation by oxidation of organic compounds GO:0015980 125 0.013
response to external stimulus GO:0009605 158 0.013
regulation of translational initiation GO:0006446 18 0.013
purine nucleoside catabolic process GO:0006152 330 0.013
cytoplasmic translation GO:0002181 65 0.013
dna conformation change GO:0071103 98 0.012
monocarboxylic acid biosynthetic process GO:0072330 35 0.012
programmed cell death GO:0012501 30 0.012
regulation of lipid catabolic process GO:0050994 4 0.012
filamentous growth GO:0030447 124 0.012
cellular cation homeostasis GO:0030003 100 0.012
mitochondrion distribution GO:0048311 21 0.012
protein ubiquitination GO:0016567 118 0.012
covalent chromatin modification GO:0016569 119 0.012
purine ribonucleotide metabolic process GO:0009150 372 0.012
oxidation reduction process GO:0055114 353 0.011
cellular component morphogenesis GO:0032989 97 0.011
carbohydrate derivative metabolic process GO:1901135 549 0.011
chromosome organization involved in meiosis GO:0070192 32 0.011
reciprocal dna recombination GO:0035825 54 0.011
positive regulation of catalytic activity GO:0043085 178 0.011
microtubule based process GO:0007017 117 0.011
apoptotic process GO:0006915 30 0.011
regulation of cellular component biogenesis GO:0044087 112 0.011
regulation of response to stimulus GO:0048583 157 0.011
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.011
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 26 0.011
phosphorylation of rna polymerase ii c terminal domain GO:0070816 20 0.011
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.011
ubiquitin dependent protein catabolic process GO:0006511 181 0.011
regulation of localization GO:0032879 127 0.010
amide transport GO:0042886 22 0.010
regulation of cellular ketone metabolic process GO:0010565 42 0.010
lipid metabolic process GO:0006629 269 0.010
dna dependent dna replication GO:0006261 115 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.010
chromatin silencing at telomere GO:0006348 84 0.010
regulation of mrna catabolic process GO:0061013 11 0.010
cytoplasmic mrna processing body assembly GO:0033962 9 0.010

DEF1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017