Saccharomyces cerevisiae

99 known processes

IRS4 (YKR019C)

Irs4p

IRS4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lipid metabolic process GO:0006629 269 0.161
single organism cellular localization GO:1902580 375 0.147
phospholipid metabolic process GO:0006644 125 0.140
organophosphate metabolic process GO:0019637 597 0.130
mitochondrion organization GO:0007005 261 0.129
cellular lipid metabolic process GO:0044255 229 0.128
glycerolipid metabolic process GO:0046486 108 0.111
glycerophospholipid metabolic process GO:0006650 98 0.105
phosphatidylinositol metabolic process GO:0046488 62 0.103
organophosphate biosynthetic process GO:0090407 182 0.097
response to chemical GO:0042221 390 0.096
chemical homeostasis GO:0048878 137 0.080
organelle localization GO:0051640 128 0.080
transmembrane transport GO:0055085 349 0.073
single organism catabolic process GO:0044712 619 0.069
cellular chemical homeostasis GO:0055082 123 0.068
cation homeostasis GO:0055080 105 0.067
cellular response to chemical stimulus GO:0070887 315 0.064
vesicle mediated transport GO:0016192 335 0.063
cellular cation homeostasis GO:0030003 100 0.060
organonitrogen compound biosynthetic process GO:1901566 314 0.060
response to organic substance GO:0010033 182 0.058
protein phosphorylation GO:0006468 197 0.058
lipid biosynthetic process GO:0008610 170 0.057
organic acid metabolic process GO:0006082 352 0.057
cellular homeostasis GO:0019725 138 0.055
carboxylic acid metabolic process GO:0019752 338 0.053
oxoacid metabolic process GO:0043436 351 0.052
ion homeostasis GO:0050801 118 0.051
protein complex assembly GO:0006461 302 0.051
translation GO:0006412 230 0.050
negative regulation of cellular metabolic process GO:0031324 407 0.048
regulation of localization GO:0032879 127 0.047
heterocycle catabolic process GO:0046700 494 0.046
homeostatic process GO:0042592 227 0.046
phosphorylation GO:0016310 291 0.046
developmental process GO:0032502 261 0.046
carbohydrate derivative metabolic process GO:1901135 549 0.046
alcohol metabolic process GO:0006066 112 0.042
positive regulation of macromolecule metabolic process GO:0010604 394 0.041
single organism developmental process GO:0044767 258 0.040
regulation of cellular component organization GO:0051128 334 0.040
positive regulation of transcription dna templated GO:0045893 286 0.040
regulation of biological quality GO:0065008 391 0.040
aromatic compound catabolic process GO:0019439 491 0.039
reproductive process GO:0022414 248 0.039
establishment of protein localization GO:0045184 367 0.039
sexual reproduction GO:0019953 216 0.039
cellular response to nutrient levels GO:0031669 144 0.039
organic cyclic compound catabolic process GO:1901361 499 0.039
protein transport GO:0015031 345 0.039
glycerophospholipid biosynthetic process GO:0046474 68 0.038
response to organic cyclic compound GO:0014070 1 0.038
protein localization to organelle GO:0033365 337 0.038
cellular developmental process GO:0048869 191 0.038
positive regulation of biosynthetic process GO:0009891 336 0.038
cellular ion homeostasis GO:0006873 112 0.037
positive regulation of transport GO:0051050 32 0.037
organelle assembly GO:0070925 118 0.037
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.037
nucleobase containing small molecule metabolic process GO:0055086 491 0.037
monocarboxylic acid metabolic process GO:0032787 122 0.036
protein targeting GO:0006605 272 0.036
cellular carbohydrate metabolic process GO:0044262 135 0.036
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.036
carbohydrate metabolic process GO:0005975 252 0.035
cellular nitrogen compound catabolic process GO:0044270 494 0.035
regulation of phosphorylation GO:0042325 86 0.035
sporulation resulting in formation of a cellular spore GO:0030435 129 0.035
nucleobase containing compound catabolic process GO:0034655 479 0.035
small molecule biosynthetic process GO:0044283 258 0.035
nucleotide metabolic process GO:0009117 453 0.035
protein complex biogenesis GO:0070271 314 0.034
regulation of transport GO:0051049 85 0.034
organophosphate catabolic process GO:0046434 338 0.034
cell differentiation GO:0030154 161 0.034
protein localization to membrane GO:0072657 102 0.034
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.034
response to external stimulus GO:0009605 158 0.034
multi organism reproductive process GO:0044703 216 0.033
small molecule catabolic process GO:0044282 88 0.033
cellular amino acid metabolic process GO:0006520 225 0.033
positive regulation of cellular biosynthetic process GO:0031328 336 0.033
intracellular protein transport GO:0006886 319 0.033
cellular ketone metabolic process GO:0042180 63 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.033
establishment of protein localization to organelle GO:0072594 278 0.033
developmental process involved in reproduction GO:0003006 159 0.033
single organism signaling GO:0044700 208 0.031
positive regulation of gene expression GO:0010628 321 0.031
membrane organization GO:0061024 276 0.031
ribonucleoprotein complex subunit organization GO:0071826 152 0.030
meiotic cell cycle GO:0051321 272 0.030
intracellular signal transduction GO:0035556 112 0.030
regulation of cellular protein metabolic process GO:0032268 232 0.030
regulation of protein metabolic process GO:0051246 237 0.029
nitrogen compound transport GO:0071705 212 0.029
nucleocytoplasmic transport GO:0006913 163 0.029
positive regulation of nucleic acid templated transcription GO:1903508 286 0.029
response to extracellular stimulus GO:0009991 156 0.029
response to nutrient levels GO:0031667 150 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.029
positive regulation of phosphate metabolic process GO:0045937 147 0.029
multi organism process GO:0051704 233 0.029
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.029
organonitrogen compound catabolic process GO:1901565 404 0.029
cellular protein complex assembly GO:0043623 209 0.028
cellular response to dna damage stimulus GO:0006974 287 0.028
cell communication GO:0007154 345 0.028
single organism membrane organization GO:0044802 275 0.028
metal ion homeostasis GO:0055065 79 0.028
single organism carbohydrate metabolic process GO:0044723 237 0.028
signaling GO:0023052 208 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.027
cellular response to oxidative stress GO:0034599 94 0.027
regulation of phosphorus metabolic process GO:0051174 230 0.027
ascospore formation GO:0030437 107 0.027
sporulation GO:0043934 132 0.027
negative regulation of macromolecule metabolic process GO:0010605 375 0.027
nucleoside phosphate metabolic process GO:0006753 458 0.026
ribonucleoprotein complex assembly GO:0022618 143 0.026
anatomical structure morphogenesis GO:0009653 160 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.026
multi organism cellular process GO:0044764 120 0.026
purine ribonucleoside metabolic process GO:0046128 380 0.025
cellular metal ion homeostasis GO:0006875 78 0.025
glycosyl compound metabolic process GO:1901657 398 0.025
anatomical structure development GO:0048856 160 0.025
negative regulation of nucleic acid templated transcription GO:1903507 260 0.025
nucleoside metabolic process GO:0009116 394 0.025
regulation of phosphate metabolic process GO:0019220 230 0.025
conjugation GO:0000746 107 0.025
negative regulation of transcription dna templated GO:0045892 258 0.025
dephosphorylation GO:0016311 127 0.025
secretion by cell GO:0032940 50 0.025
macromolecule catabolic process GO:0009057 383 0.024
sexual sporulation GO:0034293 113 0.024
single organism reproductive process GO:0044702 159 0.024
membrane lipid metabolic process GO:0006643 67 0.024
fungal type cell wall organization GO:0031505 145 0.024
organic acid biosynthetic process GO:0016053 152 0.024
response to starvation GO:0042594 96 0.023
ribonucleotide metabolic process GO:0009259 377 0.023
carbohydrate derivative catabolic process GO:1901136 339 0.023
cellular response to extracellular stimulus GO:0031668 150 0.023
regulation of molecular function GO:0065009 320 0.023
purine nucleotide metabolic process GO:0006163 376 0.023
ribose phosphate metabolic process GO:0019693 384 0.023
transition metal ion homeostasis GO:0055076 59 0.023
positive regulation of cellular component organization GO:0051130 116 0.022
nuclear transport GO:0051169 165 0.022
negative regulation of cellular biosynthetic process GO:0031327 312 0.022
organic hydroxy compound metabolic process GO:1901615 125 0.022
positive regulation of rna metabolic process GO:0051254 294 0.022
ascospore wall biogenesis GO:0070591 52 0.022
fatty acid metabolic process GO:0006631 51 0.022
filamentous growth GO:0030447 124 0.022
carbohydrate derivative biosynthetic process GO:1901137 181 0.022
growth GO:0040007 157 0.022
cellular amine metabolic process GO:0044106 51 0.021
autophagy GO:0006914 106 0.021
glycosyl compound catabolic process GO:1901658 335 0.021
phospholipid biosynthetic process GO:0008654 89 0.021
regulation of cell communication GO:0010646 124 0.021
sphingolipid metabolic process GO:0006665 41 0.021
cellular transition metal ion homeostasis GO:0046916 59 0.021
cellular macromolecule catabolic process GO:0044265 363 0.021
nucleoside triphosphate metabolic process GO:0009141 364 0.021
reproduction of a single celled organism GO:0032505 191 0.021
meiotic cell cycle process GO:1903046 229 0.020
carboxylic acid biosynthetic process GO:0046394 152 0.020
regulation of organelle organization GO:0033043 243 0.020
purine containing compound metabolic process GO:0072521 400 0.020
dna repair GO:0006281 236 0.020
protein import GO:0017038 122 0.020
regulation of catalytic activity GO:0050790 307 0.020
response to heat GO:0009408 69 0.020
regulation of vesicle mediated transport GO:0060627 39 0.019
maintenance of location GO:0051235 66 0.019
nucleobase containing compound transport GO:0015931 124 0.019
nucleoside triphosphate catabolic process GO:0009143 329 0.019
purine ribonucleotide catabolic process GO:0009154 327 0.019
chromatin silencing GO:0006342 147 0.019
regulation of protein modification process GO:0031399 110 0.019
ribosome biogenesis GO:0042254 335 0.019
positive regulation of secretion GO:0051047 2 0.018
protein modification by small protein conjugation or removal GO:0070647 172 0.018
oxidation reduction process GO:0055114 353 0.018
amine metabolic process GO:0009308 51 0.018
glycerolipid biosynthetic process GO:0045017 71 0.018
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.018
regulation of translation GO:0006417 89 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.018
positive regulation of rna biosynthetic process GO:1902680 286 0.018
reproductive process in single celled organism GO:0022413 145 0.018
ascospore wall assembly GO:0030476 52 0.018
posttranscriptional regulation of gene expression GO:0010608 115 0.018
cellular response to external stimulus GO:0071496 150 0.018
regulation of cell cycle GO:0051726 195 0.018
response to abiotic stimulus GO:0009628 159 0.018
regulation of protein phosphorylation GO:0001932 75 0.018
response to oxidative stress GO:0006979 99 0.018
regulation of catabolic process GO:0009894 199 0.018
regulation of cellular ketone metabolic process GO:0010565 42 0.018
conjugation with cellular fusion GO:0000747 106 0.018
trna metabolic process GO:0006399 151 0.018
response to temperature stimulus GO:0009266 74 0.017
signal transduction GO:0007165 208 0.017
anion transport GO:0006820 145 0.017
mitotic cell cycle GO:0000278 306 0.017
response to pheromone involved in conjugation with cellular fusion GO:0000749 74 0.017
fungal type cell wall assembly GO:0071940 53 0.017
ncrna processing GO:0034470 330 0.017
nuclear division GO:0000280 263 0.017
nucleoside phosphate catabolic process GO:1901292 331 0.017
nucleoside monophosphate metabolic process GO:0009123 267 0.017
filamentous growth of a population of unicellular organisms GO:0044182 109 0.017
positive regulation of secretion by cell GO:1903532 2 0.017
dna recombination GO:0006310 172 0.017
response to oxygen containing compound GO:1901700 61 0.017
cell wall organization GO:0071555 146 0.017
negative regulation of biosynthetic process GO:0009890 312 0.016
nuclear export GO:0051168 124 0.016
negative regulation of gene expression GO:0010629 312 0.016
purine nucleoside metabolic process GO:0042278 380 0.016
regulation of cellular catabolic process GO:0031329 195 0.016
negative regulation of rna biosynthetic process GO:1902679 260 0.016
cell division GO:0051301 205 0.016
regulation of response to stimulus GO:0048583 157 0.016
mitotic cell cycle process GO:1903047 294 0.016
ion transport GO:0006811 274 0.016
anatomical structure formation involved in morphogenesis GO:0048646 136 0.016
alcohol biosynthetic process GO:0046165 75 0.016
cellular response to starvation GO:0009267 90 0.016
cellular response to pheromone GO:0071444 88 0.016
ribonucleoside triphosphate catabolic process GO:0009203 327 0.016
phosphatidylinositol biosynthetic process GO:0006661 39 0.016
purine nucleoside monophosphate metabolic process GO:0009126 262 0.016
negative regulation of cellular protein metabolic process GO:0032269 85 0.016
organic hydroxy compound transport GO:0015850 41 0.016
nucleotide catabolic process GO:0009166 330 0.016
establishment of protein localization to membrane GO:0090150 99 0.015
endomembrane system organization GO:0010256 74 0.015
spore wall assembly GO:0042244 52 0.015
mrna metabolic process GO:0016071 269 0.015
organelle fission GO:0048285 272 0.015
response to osmotic stress GO:0006970 83 0.015
fungal type cell wall biogenesis GO:0009272 80 0.015
spore wall biogenesis GO:0070590 52 0.015
protein ubiquitination GO:0016567 118 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.015
protein modification by small protein conjugation GO:0032446 144 0.015
negative regulation of rna metabolic process GO:0051253 262 0.015
meiotic nuclear division GO:0007126 163 0.015
rna localization GO:0006403 112 0.015
fungal type cell wall organization or biogenesis GO:0071852 169 0.015
sterol transport GO:0015918 24 0.015
purine ribonucleotide metabolic process GO:0009150 372 0.015
nucleoside catabolic process GO:0009164 335 0.015
positive regulation of programmed cell death GO:0043068 3 0.015
sulfur compound metabolic process GO:0006790 95 0.015
maintenance of location in cell GO:0051651 58 0.015
ribonucleoside monophosphate metabolic process GO:0009161 265 0.014
cellular component morphogenesis GO:0032989 97 0.014
positive regulation of catabolic process GO:0009896 135 0.014
purine nucleoside triphosphate catabolic process GO:0009146 329 0.014
cell growth GO:0016049 89 0.014
rrna processing GO:0006364 227 0.014
ribonucleoside triphosphate metabolic process GO:0009199 356 0.014
macromolecular complex disassembly GO:0032984 80 0.014
positive regulation of cell death GO:0010942 3 0.014
single organism carbohydrate catabolic process GO:0044724 73 0.014
cell wall organization or biogenesis GO:0071554 190 0.014
invasive growth in response to glucose limitation GO:0001403 61 0.014
positive regulation of protein metabolic process GO:0051247 93 0.014
rrna metabolic process GO:0016072 244 0.014
organelle inheritance GO:0048308 51 0.014
lipid localization GO:0010876 60 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.014
rna transport GO:0050658 92 0.014
cellular response to organic substance GO:0071310 159 0.014
ribonucleoside metabolic process GO:0009119 389 0.013
positive regulation of apoptotic process GO:0043065 3 0.013
atp metabolic process GO:0046034 251 0.013
establishment of rna localization GO:0051236 92 0.013
regulation of growth of unicellular organism as a thread of attached cells GO:0070784 31 0.013
cellular component disassembly GO:0022411 86 0.013
generation of precursor metabolites and energy GO:0006091 147 0.013
peroxisome organization GO:0007031 68 0.013
chromatin organization GO:0006325 242 0.013
proteolysis GO:0006508 268 0.013
purine nucleoside catabolic process GO:0006152 330 0.013
positive regulation of molecular function GO:0044093 185 0.013
establishment of organelle localization GO:0051656 96 0.013
purine nucleoside triphosphate metabolic process GO:0009144 356 0.013
ribonucleotide catabolic process GO:0009261 327 0.013
regulation of carbohydrate metabolic process GO:0006109 43 0.013
cytoskeleton organization GO:0007010 230 0.013
external encapsulating structure organization GO:0045229 146 0.013
cellular response to abiotic stimulus GO:0071214 62 0.013
response to uv GO:0009411 4 0.013
positive regulation of phosphorus metabolic process GO:0010562 147 0.013
regulation of dna metabolic process GO:0051052 100 0.013
regulation of signal transduction GO:0009966 114 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.013
positive regulation of catalytic activity GO:0043085 178 0.013
gene silencing GO:0016458 151 0.012
endocytosis GO:0006897 90 0.012
response to inorganic substance GO:0010035 47 0.012
protein complex disassembly GO:0043241 70 0.012
nucleic acid transport GO:0050657 94 0.012
detection of stimulus GO:0051606 4 0.012
negative regulation of organelle organization GO:0010639 103 0.012
rna export from nucleus GO:0006405 88 0.012
purine nucleotide catabolic process GO:0006195 328 0.012
monosaccharide metabolic process GO:0005996 83 0.012
methylation GO:0032259 101 0.012
organic hydroxy compound biosynthetic process GO:1901617 81 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.012
positive regulation of intracellular transport GO:0032388 4 0.012
dna replication GO:0006260 147 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.012
cell wall assembly GO:0070726 54 0.012
cytokinesis GO:0000910 92 0.012
purine ribonucleoside catabolic process GO:0046130 330 0.012
cell development GO:0048468 107 0.012
cellular component assembly involved in morphogenesis GO:0010927 73 0.012
cellular response to heat GO:0034605 53 0.012
protein lipidation GO:0006497 40 0.012
chromatin silencing at telomere GO:0006348 84 0.012
cellular response to osmotic stress GO:0071470 50 0.012
response to pheromone GO:0019236 92 0.012
purine containing compound catabolic process GO:0072523 332 0.012
protein localization to nucleus GO:0034504 74 0.011
cellular lipid catabolic process GO:0044242 33 0.011
hexose metabolic process GO:0019318 78 0.011
regulation of filamentous growth GO:0010570 38 0.011
negative regulation of cellular component organization GO:0051129 109 0.011
response to nutrient GO:0007584 52 0.011
establishment of cell polarity GO:0030010 64 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.011
cellular response to nutrient GO:0031670 50 0.011
regulation of cellular component biogenesis GO:0044087 112 0.011
guanosine containing compound metabolic process GO:1901068 111 0.011
regulation of cellular amine metabolic process GO:0033238 21 0.011
chromatin modification GO:0016568 200 0.011
carbohydrate catabolic process GO:0016052 77 0.011
establishment of protein localization to vacuole GO:0072666 91 0.011
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 22 0.011
alpha amino acid metabolic process GO:1901605 124 0.011
protein maturation GO:0051604 76 0.011
pseudohyphal growth GO:0007124 75 0.011
ribonucleoside catabolic process GO:0042454 332 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.011
negative regulation of gene expression epigenetic GO:0045814 147 0.011
cell wall biogenesis GO:0042546 93 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
regulation of signaling GO:0023051 119 0.011
cofactor metabolic process GO:0051186 126 0.011
cofactor biosynthetic process GO:0051188 80 0.011
cellular protein catabolic process GO:0044257 213 0.011
ras protein signal transduction GO:0007265 29 0.011
regulation of hydrolase activity GO:0051336 133 0.011
nucleoside monophosphate catabolic process GO:0009125 224 0.011
regulation of cellular amino acid metabolic process GO:0006521 16 0.011
maintenance of protein location GO:0045185 53 0.011
vacuole organization GO:0007033 75 0.010
cell cycle checkpoint GO:0000075 82 0.010
proteasomal protein catabolic process GO:0010498 141 0.010
regulation of metal ion transport GO:0010959 2 0.010
cellular amino acid catabolic process GO:0009063 48 0.010
nucleoside phosphate biosynthetic process GO:1901293 80 0.010
maintenance of protein location in cell GO:0032507 50 0.010
small gtpase mediated signal transduction GO:0007264 36 0.010
cellular amide metabolic process GO:0043603 59 0.010
iron ion homeostasis GO:0055072 34 0.010
response to reactive oxygen species GO:0000302 22 0.010
rna 3 end processing GO:0031123 88 0.010
transition metal ion transport GO:0000041 45 0.010
ribosomal small subunit biogenesis GO:0042274 124 0.010
covalent chromatin modification GO:0016569 119 0.010
carboxylic acid catabolic process GO:0046395 71 0.010
response to hypoxia GO:0001666 4 0.010
cellular iron ion homeostasis GO:0006879 34 0.010
mitochondrial translation GO:0032543 52 0.010

IRS4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.012