Saccharomyces cerevisiae

139 known processes

HSP60 (YLR259C)

Hsp60p

(Aliases: MNA2,MIF4,CPN60)

HSP60 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitochondrion organization GO:0007005 261 0.960
protein folding GO:0006457 94 0.913
protein import GO:0017038 122 0.898
protein localization to mitochondrion GO:0070585 63 0.894
organic acid metabolic process GO:0006082 352 0.878
protein transmembrane transport GO:0071806 82 0.849
protein refolding GO:0042026 16 0.771
intracellular protein transmembrane transport GO:0065002 80 0.714
cell communication GO:0007154 345 0.696
transmembrane transport GO:0055085 349 0.556
establishment of protein localization to organelle GO:0072594 278 0.543
regulation of cell communication GO:0010646 124 0.484
mitochondrial transport GO:0006839 76 0.481
response to organic substance GO:0010033 182 0.462
protein targeting GO:0006605 272 0.460
carboxylic acid metabolic process GO:0019752 338 0.440
cellular amino acid catabolic process GO:0009063 48 0.430
oxoacid metabolic process GO:0043436 351 0.404
intracellular protein transport GO:0006886 319 0.403
protein targeting to mitochondrion GO:0006626 56 0.400
signal transduction GO:0007165 208 0.386
establishment of protein localization to mitochondrion GO:0072655 63 0.356
cell aging GO:0007569 70 0.351
single organism signaling GO:0044700 208 0.333
signaling GO:0023052 208 0.302
regulation of signaling GO:0023051 119 0.295
positive regulation of macromolecule metabolic process GO:0010604 394 0.284
single organism developmental process GO:0044767 258 0.259
Zebrafish
alpha amino acid metabolic process GO:1901605 124 0.237
organonitrogen compound catabolic process GO:1901565 404 0.236
cellular response to organic substance GO:0071310 159 0.235
cellular amino acid metabolic process GO:0006520 225 0.223
regulation of signal transduction GO:0009966 114 0.212
single organism cellular localization GO:1902580 375 0.210
protein phosphorylation GO:0006468 197 0.201
establishment of protein localization GO:0045184 367 0.198
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.197
protein transport GO:0015031 345 0.176
regulation of biological quality GO:0065008 391 0.168
external encapsulating structure organization GO:0045229 146 0.167
single organism catabolic process GO:0044712 619 0.162
carboxylic acid biosynthetic process GO:0046394 152 0.158
translation GO:0006412 230 0.158
alpha amino acid catabolic process GO:1901606 28 0.154
protein localization to organelle GO:0033365 337 0.153
alpha amino acid biosynthetic process GO:1901607 91 0.151
nucleocytoplasmic transport GO:0006913 163 0.133
regulation of response to stimulus GO:0048583 157 0.130
protein complex assembly GO:0006461 302 0.128
regulation of molecular function GO:0065009 320 0.127
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.127
intracellular signal transduction GO:0035556 112 0.122
small molecule biosynthetic process GO:0044283 258 0.116
organic acid biosynthetic process GO:0016053 152 0.113
nitrogen compound transport GO:0071705 212 0.113
negative regulation of signal transduction GO:0009968 30 0.112
response to chemical GO:0042221 390 0.110
homeostatic process GO:0042592 227 0.106
growth GO:0040007 157 0.103
Zebrafish
regulation of protein metabolic process GO:0051246 237 0.092
aromatic compound catabolic process GO:0019439 491 0.092
negative regulation of signaling GO:0023057 30 0.091
positive regulation of phosphate metabolic process GO:0045937 147 0.090
regulation of cellular component organization GO:0051128 334 0.089
cellular protein complex assembly GO:0043623 209 0.087
organonitrogen compound biosynthetic process GO:1901566 314 0.085
positive regulation of catalytic activity GO:0043085 178 0.081
chromatin modification GO:0016568 200 0.080
positive regulation of gene expression GO:0010628 321 0.077
cell wall organization GO:0071555 146 0.076
regulation of intracellular signal transduction GO:1902531 78 0.075
cytoplasmic translation GO:0002181 65 0.074
positive regulation of cellular biosynthetic process GO:0031328 336 0.070
regulation of phosphate metabolic process GO:0019220 230 0.069
intracellular protein transmembrane import GO:0044743 67 0.067
glycosyl compound metabolic process GO:1901657 398 0.066
ribonucleoprotein complex subunit organization GO:0071826 152 0.064
mapk cascade GO:0000165 30 0.062
small molecule catabolic process GO:0044282 88 0.061
heterocycle catabolic process GO:0046700 494 0.060
developmental process GO:0032502 261 0.057
Zebrafish
anion transport GO:0006820 145 0.057
response to external stimulus GO:0009605 158 0.056
regulation of phosphorus metabolic process GO:0051174 230 0.056
carbohydrate derivative catabolic process GO:1901136 339 0.055
protein maturation GO:0051604 76 0.054
organic acid catabolic process GO:0016054 71 0.054
phosphorylation GO:0016310 291 0.053
trna metabolic process GO:0006399 151 0.052
negative regulation of macromolecule metabolic process GO:0010605 375 0.051
ribonucleoside metabolic process GO:0009119 389 0.051
purine containing compound metabolic process GO:0072521 400 0.050
nucleoside metabolic process GO:0009116 394 0.049
positive regulation of molecular function GO:0044093 185 0.048
nucleobase containing compound catabolic process GO:0034655 479 0.048
negative regulation of response to stimulus GO:0048585 40 0.047
cellular cation homeostasis GO:0030003 100 0.046
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.046
carbohydrate derivative metabolic process GO:1901135 549 0.045
cellular nitrogen compound catabolic process GO:0044270 494 0.045
oxidation reduction process GO:0055114 353 0.045
nucleobase containing compound transport GO:0015931 124 0.045
regulation of cellular catabolic process GO:0031329 195 0.044
aging GO:0007568 71 0.044
branched chain amino acid metabolic process GO:0009081 16 0.043
regulation of catalytic activity GO:0050790 307 0.043
negative regulation of cell communication GO:0010648 33 0.042
negative regulation of cellular metabolic process GO:0031324 407 0.042
carboxylic acid catabolic process GO:0046395 71 0.041
nuclear import GO:0051170 57 0.041
meiotic cell cycle GO:0051321 272 0.041
regulation of cellular protein metabolic process GO:0032268 232 0.040
anatomical structure development GO:0048856 160 0.039
Zebrafish
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.039
ion transport GO:0006811 274 0.039
response to organonitrogen compound GO:0010243 18 0.038
protein complex biogenesis GO:0070271 314 0.038
cellular response to chemical stimulus GO:0070887 315 0.038
protein processing GO:0016485 64 0.038
fungal type cell wall organization or biogenesis GO:0071852 169 0.037
response to extracellular stimulus GO:0009991 156 0.037
monosaccharide metabolic process GO:0005996 83 0.037
organelle fission GO:0048285 272 0.036
nucleoside catabolic process GO:0009164 335 0.035
positive regulation of apoptotic process GO:0043065 3 0.035
cellular amino acid biosynthetic process GO:0008652 118 0.035
response to reactive oxygen species GO:0000302 22 0.034
glycosyl compound catabolic process GO:1901658 335 0.034
signal transduction by phosphorylation GO:0023014 31 0.034
cellular response to heat GO:0034605 53 0.034
coenzyme biosynthetic process GO:0009108 66 0.033
ribonucleoside catabolic process GO:0042454 332 0.033
maintenance of location in cell GO:0051651 58 0.033
ribonucleotide catabolic process GO:0009261 327 0.033
positive regulation of cell death GO:0010942 3 0.032
positive regulation of biosynthetic process GO:0009891 336 0.032
purine nucleoside catabolic process GO:0006152 330 0.032
purine containing compound catabolic process GO:0072523 332 0.032
regulation of catabolic process GO:0009894 199 0.032
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.032
nucleobase containing small molecule metabolic process GO:0055086 491 0.032
reproductive process GO:0022414 248 0.031
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.031
regulation of cellular component biogenesis GO:0044087 112 0.031
regulation of transferase activity GO:0051338 83 0.031
protein export from nucleus GO:0006611 17 0.030
negative regulation of cellular protein metabolic process GO:0032269 85 0.030
regulation of protein phosphorylation GO:0001932 75 0.030
response to topologically incorrect protein GO:0035966 38 0.030
vesicle mediated transport GO:0016192 335 0.030
iron ion homeostasis GO:0055072 34 0.030
ribonucleotide metabolic process GO:0009259 377 0.029
rrna metabolic process GO:0016072 244 0.028
response to nutrient levels GO:0031667 150 0.028
regulation of cellular localization GO:0060341 50 0.028
replicative cell aging GO:0001302 46 0.028
mitochondrion degradation GO:0000422 29 0.028
positive regulation of programmed cell death GO:0043068 3 0.028
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.027
response to heat GO:0009408 69 0.027
rrna processing GO:0006364 227 0.027
ion homeostasis GO:0050801 118 0.027
protein ubiquitination GO:0016567 118 0.027
covalent chromatin modification GO:0016569 119 0.026
negative regulation of gene expression GO:0010629 312 0.026
negative regulation of protein metabolic process GO:0051248 85 0.026
mrna metabolic process GO:0016071 269 0.026
glycosyl compound biosynthetic process GO:1901659 42 0.026
positive regulation of protein metabolic process GO:0051247 93 0.026
cytoskeleton organization GO:0007010 230 0.026
organophosphate metabolic process GO:0019637 597 0.025
purine ribonucleotide metabolic process GO:0009150 372 0.025
single organism nuclear import GO:1902593 56 0.025
nucleotide metabolic process GO:0009117 453 0.025
purine nucleoside metabolic process GO:0042278 380 0.025
mrna catabolic process GO:0006402 93 0.025
leucine metabolic process GO:0006551 8 0.024
secretion GO:0046903 50 0.024
positive regulation of signaling GO:0023056 20 0.024
organic cyclic compound catabolic process GO:1901361 499 0.024
generation of precursor metabolites and energy GO:0006091 147 0.024
multi organism reproductive process GO:0044703 216 0.024
nucleoside phosphate metabolic process GO:0006753 458 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.023
macromolecule catabolic process GO:0009057 383 0.023
negative regulation of nucleic acid templated transcription GO:1903507 260 0.023
cellular response to external stimulus GO:0071496 150 0.023
positive regulation of transcription dna templated GO:0045893 286 0.023
sexual reproduction GO:0019953 216 0.023
positive regulation of secretion by cell GO:1903532 2 0.023
response to unfolded protein GO:0006986 29 0.023
nucleoside triphosphate catabolic process GO:0009143 329 0.023
purine nucleoside triphosphate catabolic process GO:0009146 329 0.023
negative regulation of transcription dna templated GO:0045892 258 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 100 0.022
positive regulation of cellular catabolic process GO:0031331 128 0.022
negative regulation of rna biosynthetic process GO:1902679 260 0.022
chemical homeostasis GO:0048878 137 0.022
protein import into nucleus GO:0006606 55 0.022
response to organic cyclic compound GO:0014070 1 0.022
negative regulation of intracellular signal transduction GO:1902532 27 0.022
ribonucleoside triphosphate catabolic process GO:0009203 327 0.022
response to abiotic stimulus GO:0009628 159 0.021
positive regulation of phosphorus metabolic process GO:0010562 147 0.021
response to starvation GO:0042594 96 0.021
purine ribonucleoside metabolic process GO:0046128 380 0.021
regulation of transport GO:0051049 85 0.021
nucleic acid transport GO:0050657 94 0.021
monocarboxylic acid metabolic process GO:0032787 122 0.021
negative regulation of cellular biosynthetic process GO:0031327 312 0.021
cellular response to nutrient levels GO:0031669 144 0.021
ribosome biogenesis GO:0042254 335 0.020
detection of stimulus GO:0051606 4 0.020
response to oxygen containing compound GO:1901700 61 0.020
anatomical structure morphogenesis GO:0009653 160 0.020
sulfur compound transport GO:0072348 19 0.020
meiotic cell cycle process GO:1903046 229 0.020
protein import into mitochondrial intermembrane space GO:0045041 7 0.020
positive regulation of nucleotide metabolic process GO:0045981 101 0.019
establishment of organelle localization GO:0051656 96 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.019
positive regulation of secretion GO:0051047 2 0.019
regulation of dna metabolic process GO:0051052 100 0.019
posttranscriptional regulation of gene expression GO:0010608 115 0.019
nucleotide catabolic process GO:0009166 330 0.019
single organism reproductive process GO:0044702 159 0.019
positive regulation of catabolic process GO:0009896 135 0.019
cellular metal ion homeostasis GO:0006875 78 0.019
organelle localization GO:0051640 128 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
regulation of hydrolase activity GO:0051336 133 0.019
chronological cell aging GO:0001300 28 0.019
mitotic cell cycle process GO:1903047 294 0.019
protein modification by small protein conjugation or removal GO:0070647 172 0.019
cell wall organization or biogenesis GO:0071554 190 0.018
organelle assembly GO:0070925 118 0.018
negative regulation of cellular component organization GO:0051129 109 0.018
cellular respiration GO:0045333 82 0.018
regulation of kinase activity GO:0043549 71 0.018
rna localization GO:0006403 112 0.018
regulation of organelle organization GO:0033043 243 0.018
cellular response to extracellular stimulus GO:0031668 150 0.018
purine nucleotide catabolic process GO:0006195 328 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.018
nucleoside phosphate catabolic process GO:1901292 331 0.018
cation transport GO:0006812 166 0.017
nuclear division GO:0000280 263 0.017
regulation of cellular ketone metabolic process GO:0010565 42 0.017
branched chain amino acid biosynthetic process GO:0009082 13 0.017
positive regulation of hydrolase activity GO:0051345 112 0.017
conjugation GO:0000746 107 0.017
regulation of mapk cascade GO:0043408 22 0.017
proteolysis GO:0006508 268 0.017
chaperone mediated protein folding GO:0061077 3 0.016
nuclear transport GO:0051169 165 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.016
organophosphate biosynthetic process GO:0090407 182 0.016
anion transmembrane transport GO:0098656 79 0.016
ribonucleoprotein complex assembly GO:0022618 143 0.016
ncrna processing GO:0034470 330 0.016
chromatin organization GO:0006325 242 0.016
regulation of protein serine threonine kinase activity GO:0071900 41 0.016
regulation of proteolysis GO:0030162 44 0.015
regulation of protein kinase activity GO:0045859 67 0.015
protein targeting to nucleus GO:0044744 57 0.015
regulation of carbohydrate biosynthetic process GO:0043255 31 0.015
mitochondrial translation GO:0032543 52 0.015
positive regulation of phosphorylation GO:0042327 33 0.015
organophosphate catabolic process GO:0046434 338 0.015
tricarboxylic acid metabolic process GO:0072350 3 0.015
cytoskeleton dependent cytokinesis GO:0061640 65 0.015
response to nitrogen compound GO:1901698 18 0.015
positive regulation of cellular protein metabolic process GO:0032270 89 0.015
cellular transition metal ion homeostasis GO:0046916 59 0.015
multi organism cellular process GO:0044764 120 0.015
cellular protein catabolic process GO:0044257 213 0.015
regulation of protein modification process GO:0031399 110 0.015
cellular component morphogenesis GO:0032989 97 0.015
protein modification by small protein conjugation GO:0032446 144 0.014
ribonucleoside triphosphate metabolic process GO:0009199 356 0.014
regulation of gene expression epigenetic GO:0040029 147 0.014
leucine biosynthetic process GO:0009098 5 0.014
polysaccharide biosynthetic process GO:0000271 39 0.014
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 51 0.014
response to inorganic substance GO:0010035 47 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.014
organic anion transport GO:0015711 114 0.014
regulation of phosphorylation GO:0042325 86 0.014
death GO:0016265 30 0.014
response to temperature stimulus GO:0009266 74 0.014
purine nucleotide metabolic process GO:0006163 376 0.014
response to metal ion GO:0010038 24 0.013
response to hypoxia GO:0001666 4 0.013
maintenance of location GO:0051235 66 0.013
carbohydrate derivative biosynthetic process GO:1901137 181 0.013
mitotic cell cycle GO:0000278 306 0.013
positive regulation of response to stimulus GO:0048584 37 0.013
peptidyl amino acid modification GO:0018193 116 0.013
regulation of cellular response to stress GO:0080135 50 0.013
ribose phosphate metabolic process GO:0019693 384 0.013
regulation of localization GO:0032879 127 0.013
response to oxidative stress GO:0006979 99 0.013
regulation of mrna splicing via spliceosome GO:0048024 3 0.013
stress activated protein kinase signaling cascade GO:0031098 4 0.013
purine nucleotide biosynthetic process GO:0006164 41 0.013
pyridine containing compound metabolic process GO:0072524 53 0.013
histone modification GO:0016570 119 0.013
cellular developmental process GO:0048869 191 0.012
secretion by cell GO:0032940 50 0.012
positive regulation of cell communication GO:0010647 28 0.012
cellular response to dna damage stimulus GO:0006974 287 0.012
regulation of map kinase activity GO:0043405 12 0.012
sulfur compound metabolic process GO:0006790 95 0.011
regulation of translation GO:0006417 89 0.011
response to uv GO:0009411 4 0.011
cell surface receptor signaling pathway GO:0007166 38 0.011
purine nucleoside triphosphate metabolic process GO:0009144 356 0.011
stress activated mapk cascade GO:0051403 4 0.011
cofactor biosynthetic process GO:0051188 80 0.011
cellular carbohydrate catabolic process GO:0044275 33 0.011
regulation of protein localization GO:0032880 62 0.011
negative regulation of rna metabolic process GO:0051253 262 0.011
purine ribonucleotide catabolic process GO:0009154 327 0.011
positive regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0036091 3 0.011
organic hydroxy compound biosynthetic process GO:1901617 81 0.010
purine ribonucleoside catabolic process GO:0046130 330 0.010
regulation of carbohydrate metabolic process GO:0006109 43 0.010
cellular response to hypoxia GO:0071456 4 0.010
purine nucleoside monophosphate catabolic process GO:0009128 224 0.010
cellular homeostasis GO:0019725 138 0.010
rna catabolic process GO:0006401 118 0.010
rrna containing ribonucleoprotein complex export from nucleus GO:0071428 46 0.010

HSP60 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017