Saccharomyces cerevisiae

97 known processes

ATG4 (YNL223W)

Atg4p

(Aliases: APG4,AUT2)

ATG4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleophagy GO:0044804 34 0.980
membrane invagination GO:0010324 43 0.978
single organism membrane invagination GO:1902534 43 0.973
microautophagy GO:0016237 43 0.972
piecemeal microautophagy of nucleus GO:0034727 33 0.971
macroautophagy GO:0016236 55 0.967
mitochondrion degradation GO:0000422 29 0.943
late nucleophagy GO:0044805 17 0.936
cvt pathway GO:0032258 37 0.935
autophagy GO:0006914 106 0.913
protein targeting to vacuole GO:0006623 91 0.892
protein localization to vacuole GO:0072665 92 0.842
cellular response to nutrient levels GO:0031669 144 0.837
establishment of protein localization to vacuole GO:0072666 91 0.825
vacuolar transport GO:0007034 145 0.802
cell communication GO:0007154 345 0.732
establishment of protein localization to organelle GO:0072594 278 0.723
protein targeting GO:0006605 272 0.653
cellular response to starvation GO:0009267 90 0.540
autophagic vacuole assembly GO:0000045 16 0.487
cellular response to extracellular stimulus GO:0031668 150 0.478
response to external stimulus GO:0009605 158 0.459
response to extracellular stimulus GO:0009991 156 0.408
cellular response to external stimulus GO:0071496 150 0.405
response to starvation GO:0042594 96 0.358
regulation of response to stimulus GO:0048583 157 0.349
protein localization to organelle GO:0033365 337 0.339
regulation of cellular protein metabolic process GO:0032268 232 0.306
response to nutrient levels GO:0031667 150 0.284
single organism catabolic process GO:0044712 619 0.234
membrane organization GO:0061024 276 0.227
intracellular protein transport GO:0006886 319 0.212
single organism signaling GO:0044700 208 0.206
establishment of protein localization GO:0045184 367 0.205
developmental process GO:0032502 261 0.203
regulation of protein metabolic process GO:0051246 237 0.201
phosphorylation GO:0016310 291 0.198
protein phosphorylation GO:0006468 197 0.195
regulation of cell communication GO:0010646 124 0.188
regulation of macroautophagy GO:0016241 15 0.184
single organism membrane organization GO:0044802 275 0.177
organelle assembly GO:0070925 118 0.171
vacuole organization GO:0007033 75 0.168
cellular lipid metabolic process GO:0044255 229 0.152
signaling GO:0023052 208 0.137
protein transport GO:0015031 345 0.113
single organism cellular localization GO:1902580 375 0.108
regulation of molecular function GO:0065009 320 0.105
c terminal protein lipidation GO:0006501 6 0.105
endosomal transport GO:0016197 86 0.099
regulation of autophagy GO:0010506 18 0.097
Human Fly
lipid metabolic process GO:0006629 269 0.093
regulation of signal transduction GO:0009966 114 0.089
positive regulation of protein metabolic process GO:0051247 93 0.086
single organism developmental process GO:0044767 258 0.086
regulation of cellular response to stress GO:0080135 50 0.083
protein modification by small protein conjugation or removal GO:0070647 172 0.081
organic cyclic compound catabolic process GO:1901361 499 0.075
positive regulation of cellular protein metabolic process GO:0032270 89 0.073
cellular component morphogenesis GO:0032989 97 0.073
regulation of biological quality GO:0065008 391 0.071
lipoprotein biosynthetic process GO:0042158 40 0.069
aromatic compound catabolic process GO:0019439 491 0.068
chemical homeostasis GO:0048878 137 0.067
regulation of signaling GO:0023051 119 0.067
translation GO:0006412 230 0.067
rna catabolic process GO:0006401 118 0.065
cellular response to chemical stimulus GO:0070887 315 0.064
regulation of response to extracellular stimulus GO:0032104 20 0.063
nitrogen compound transport GO:0071705 212 0.063
vesicle mediated transport GO:0016192 335 0.062
retrograde transport endosome to golgi GO:0042147 33 0.061
negative regulation of macromolecule metabolic process GO:0010605 375 0.059
protein lipidation GO:0006497 40 0.057
cellular chemical homeostasis GO:0055082 123 0.056
cellular macromolecule catabolic process GO:0044265 363 0.055
modification dependent macromolecule catabolic process GO:0043632 203 0.054
proteolysis GO:0006508 268 0.054
negative regulation of cellular biosynthetic process GO:0031327 312 0.053
regulation of response to external stimulus GO:0032101 20 0.053
protein modification by small protein conjugation GO:0032446 144 0.053
regulation of cellular component biogenesis GO:0044087 112 0.051
signal transduction GO:0007165 208 0.051
nucleobase containing compound catabolic process GO:0034655 479 0.050
positive regulation of apoptotic process GO:0043065 3 0.049
homeostatic process GO:0042592 227 0.049
regulation of catabolic process GO:0009894 199 0.049
Human Fly
regulation of transferase activity GO:0051338 83 0.049
lipid biosynthetic process GO:0008610 170 0.048
sphingolipid metabolic process GO:0006665 41 0.048
regulation of protein modification process GO:0031399 110 0.047
positive regulation of protein modification process GO:0031401 49 0.047
macromolecule catabolic process GO:0009057 383 0.046
regulation of protein catabolic process GO:0042176 40 0.042
glycosyl compound metabolic process GO:1901657 398 0.042
cellular homeostasis GO:0019725 138 0.042
regulation of cellular catabolic process GO:0031329 195 0.039
Human Fly
signal transduction by phosphorylation GO:0023014 31 0.039
regulation of catalytic activity GO:0050790 307 0.039
glycerolipid metabolic process GO:0046486 108 0.039
negative regulation of biosynthetic process GO:0009890 312 0.039
reproduction of a single celled organism GO:0032505 191 0.039
negative regulation of gene expression GO:0010629 312 0.038
posttranscriptional regulation of gene expression GO:0010608 115 0.037
protein complex assembly GO:0006461 302 0.036
positive regulation of catalytic activity GO:0043085 178 0.036
anatomical structure morphogenesis GO:0009653 160 0.035
negative regulation of transcription dna templated GO:0045892 258 0.033
mitochondrion organization GO:0007005 261 0.033
peroxisome organization GO:0007031 68 0.033
protein catabolic process GO:0030163 221 0.033
negative regulation of signal transduction GO:0009968 30 0.033
regulation of proteolysis GO:0030162 44 0.033
phospholipid metabolic process GO:0006644 125 0.033
negative regulation of cellular metabolic process GO:0031324 407 0.033
microtubule based process GO:0007017 117 0.031
ion transport GO:0006811 274 0.031
negative regulation of rna biosynthetic process GO:1902679 260 0.030
multi organism reproductive process GO:0044703 216 0.030
negative regulation of cell communication GO:0010648 33 0.030
regulation of cellular component organization GO:0051128 334 0.030
microtubule cytoskeleton organization GO:0000226 109 0.030
positive regulation of macromolecule metabolic process GO:0010604 394 0.029
regulation of translation GO:0006417 89 0.029
regulation of protein kinase activity GO:0045859 67 0.029
regulation of anatomical structure size GO:0090066 50 0.028
response to chemical GO:0042221 390 0.028
cellular component assembly involved in morphogenesis GO:0010927 73 0.028
endomembrane system organization GO:0010256 74 0.028
cell development GO:0048468 107 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.027
anatomical structure development GO:0048856 160 0.027
positive regulation of molecular function GO:0044093 185 0.027
regulation of protein phosphorylation GO:0001932 75 0.027
response to organic cyclic compound GO:0014070 1 0.027
lipoprotein metabolic process GO:0042157 40 0.027
cellular lipid catabolic process GO:0044242 33 0.026
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.026
regulation of response to nutrient levels GO:0032107 20 0.026
mitotic cell cycle phase transition GO:0044772 141 0.026
positive regulation of response to stimulus GO:0048584 37 0.026
regulation of mitochondrion organization GO:0010821 20 0.026
cellular respiration GO:0045333 82 0.025
amino acid transport GO:0006865 45 0.025
positive regulation of cell death GO:0010942 3 0.024
cellular cation homeostasis GO:0030003 100 0.024
regulation of phosphate metabolic process GO:0019220 230 0.024
protein ubiquitination GO:0016567 118 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.024
positive regulation of programmed cell death GO:0043068 3 0.024
protein complex disassembly GO:0043241 70 0.024
growth GO:0040007 157 0.024
proteasomal protein catabolic process GO:0010498 141 0.024
positive regulation of lipid catabolic process GO:0050996 4 0.023
regulation of chromosome organization GO:0033044 66 0.023
positive regulation of translation GO:0045727 34 0.023
mitochondrial translation GO:0032543 52 0.023
nucleobase containing small molecule metabolic process GO:0055086 491 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.023
positive regulation of organelle organization GO:0010638 85 0.023
multi organism process GO:0051704 233 0.022
nucleobase containing compound transport GO:0015931 124 0.022
positive regulation of catabolic process GO:0009896 135 0.022
Human Fly
ion transmembrane transport GO:0034220 200 0.022
ribose phosphate metabolic process GO:0019693 384 0.022
cellular nitrogen compound catabolic process GO:0044270 494 0.022
protein complex biogenesis GO:0070271 314 0.021
response to pheromone GO:0019236 92 0.021
carbohydrate biosynthetic process GO:0016051 82 0.021
vacuole fusion GO:0097576 40 0.021
positive regulation of hydrolase activity GO:0051345 112 0.021
c terminal protein amino acid modification GO:0018410 8 0.021
fungal type cell wall organization GO:0031505 145 0.021
cell morphogenesis GO:0000902 30 0.021
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.021
regulation of intracellular signal transduction GO:1902531 78 0.021
aging GO:0007568 71 0.021
protein processing GO:0016485 64 0.020
cellular response to organic substance GO:0071310 159 0.020
cellular response to oxygen containing compound GO:1901701 43 0.020
purine nucleotide metabolic process GO:0006163 376 0.020
multi organism cellular process GO:0044764 120 0.020
mitotic cell cycle GO:0000278 306 0.020
cellular ion homeostasis GO:0006873 112 0.020
ribonucleotide metabolic process GO:0009259 377 0.020
ascospore formation GO:0030437 107 0.020
intracellular signal transduction GO:0035556 112 0.020
response to pheromone involved in conjugation with cellular fusion GO:0000749 74 0.019
positive regulation of cellular biosynthetic process GO:0031328 336 0.019
regulation of mitosis GO:0007088 65 0.019
positive regulation of cellular component organization GO:0051130 116 0.019
apoptotic process GO:0006915 30 0.019
programmed cell death GO:0012501 30 0.019
positive regulation of transcription from rna polymerase ii promoter by oleic acid GO:0061429 4 0.019
carboxylic acid transport GO:0046942 74 0.019
positive regulation of cellular catabolic process GO:0031331 128 0.018
Human Fly
organelle localization GO:0051640 128 0.018
regulation of cellular component size GO:0032535 50 0.018
regulation of response to stress GO:0080134 57 0.018
heterocycle catabolic process GO:0046700 494 0.018
lipid localization GO:0010876 60 0.018
cell cycle checkpoint GO:0000075 82 0.018
negative regulation of rna metabolic process GO:0051253 262 0.018
organic acid transport GO:0015849 77 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.018
positive regulation of transferase activity GO:0051347 28 0.017
ion homeostasis GO:0050801 118 0.017
ribonucleoside triphosphate metabolic process GO:0009199 356 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.017
regulation of dna replication GO:0006275 51 0.017
asexual reproduction GO:0019954 48 0.017
positive regulation of gene expression GO:0010628 321 0.017
cellular ketone metabolic process GO:0042180 63 0.017
sphingolipid biosynthetic process GO:0030148 29 0.016
cellular protein catabolic process GO:0044257 213 0.016
organelle fission GO:0048285 272 0.016
regulation of cellular ketone metabolic process GO:0010565 42 0.016
regulation of glucan biosynthetic process GO:0010962 11 0.016
negative regulation of cellular protein metabolic process GO:0032269 85 0.016
nucleotide metabolic process GO:0009117 453 0.016
death GO:0016265 30 0.016
lipid catabolic process GO:0016042 33 0.016
cellular developmental process GO:0048869 191 0.015
dephosphorylation GO:0016311 127 0.015
nucleoside metabolic process GO:0009116 394 0.015
golgi vesicle transport GO:0048193 188 0.015
regulation of transport GO:0051049 85 0.015
negative regulation of catalytic activity GO:0043086 60 0.015
regulation of metal ion transport GO:0010959 2 0.015
regulation of cellular protein catabolic process GO:1903362 36 0.015
pseudohyphal growth GO:0007124 75 0.015
energy derivation by oxidation of organic compounds GO:0015980 125 0.015
external encapsulating structure organization GO:0045229 146 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.015
negative regulation of nucleic acid templated transcription GO:1903507 260 0.014
organophosphate metabolic process GO:0019637 597 0.014
nucleoside triphosphate metabolic process GO:0009141 364 0.014
alcohol metabolic process GO:0006066 112 0.014
response to inorganic substance GO:0010035 47 0.014
carbohydrate derivative metabolic process GO:1901135 549 0.014
cytoskeleton organization GO:0007010 230 0.014
negative regulation of cellular catabolic process GO:0031330 43 0.014
fungal type cell wall biogenesis GO:0009272 80 0.014
regulation of organelle organization GO:0033043 243 0.014
organelle inheritance GO:0048308 51 0.014
cell budding GO:0007114 48 0.014
nuclear transport GO:0051169 165 0.014
lipid modification GO:0030258 37 0.013
reproductive process GO:0022414 248 0.013
purine nucleoside metabolic process GO:0042278 380 0.013
regulation of cytoskeleton organization GO:0051493 63 0.013
metal ion transport GO:0030001 75 0.013
membrane lipid metabolic process GO:0006643 67 0.013
cation homeostasis GO:0055080 105 0.013
vacuole fusion non autophagic GO:0042144 40 0.013
regulation of glucose metabolic process GO:0010906 27 0.013
negative regulation of protein metabolic process GO:0051248 85 0.013
conjugation with cellular fusion GO:0000747 106 0.013
dna dependent dna replication GO:0006261 115 0.013
cell death GO:0008219 30 0.013
generation of precursor metabolites and energy GO:0006091 147 0.013
protein complex localization GO:0031503 32 0.013
purine containing compound metabolic process GO:0072521 400 0.012
modification dependent protein catabolic process GO:0019941 181 0.012
anatomical structure formation involved in morphogenesis GO:0048646 136 0.012
positive regulation of response to external stimulus GO:0032103 12 0.012
positive regulation of cell communication GO:0010647 28 0.012
invasive filamentous growth GO:0036267 65 0.012
positive regulation of nucleotide metabolic process GO:0045981 101 0.012
regulation of carbohydrate biosynthetic process GO:0043255 31 0.012
protein maturation GO:0051604 76 0.012
chromatin silencing GO:0006342 147 0.012
er to golgi vesicle mediated transport GO:0006888 86 0.012
mitochondrial rna metabolic process GO:0000959 24 0.012
reproductive process in single celled organism GO:0022413 145 0.012
spindle pole body organization GO:0051300 33 0.012
positive regulation of intracellular protein transport GO:0090316 3 0.011
carbohydrate derivative catabolic process GO:1901136 339 0.011
mitotic cell cycle process GO:1903047 294 0.011
positive regulation of transcription by oleic acid GO:0061421 4 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 29 0.011
mitotic cytokinesis GO:0000281 58 0.011
sexual reproduction GO:0019953 216 0.011
ribonucleoside metabolic process GO:0009119 389 0.011
cellular protein complex localization GO:0034629 28 0.011
dna replication GO:0006260 147 0.011
positive regulation of cytoplasmic transport GO:1903651 4 0.011
protein dephosphorylation GO:0006470 40 0.011
negative regulation of signaling GO:0023057 30 0.011
positive regulation of response to nutrient levels GO:0032109 12 0.011
filamentous growth GO:0030447 124 0.011
purine ribonucleotide metabolic process GO:0009150 372 0.011
positive regulation of nucleic acid templated transcription GO:1903508 286 0.011
regulation of hydrolase activity GO:0051336 133 0.011
positive regulation of macroautophagy GO:0016239 8 0.011
organic hydroxy compound metabolic process GO:1901615 125 0.011
cellular response to osmotic stress GO:0071470 50 0.011
cell wall organization or biogenesis GO:0071554 190 0.011
regulation of lipid catabolic process GO:0050994 4 0.010
ubiquitin dependent protein catabolic process GO:0006511 181 0.010
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.010
positive regulation of protein modification by small protein conjugation or removal GO:1903322 12 0.010
regulation of transporter activity GO:0032409 1 0.010
cell differentiation GO:0030154 161 0.010
cell cycle g1 s phase transition GO:0044843 64 0.010
regulation of lipid metabolic process GO:0019216 45 0.010

ATG4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.011