Saccharomyces cerevisiae

72 known processes

RAT1 (YOR048C)

Rat1p

(Aliases: TAP1,HKE1,XRN2)

RAT1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear rna surveillance GO:0071027 30 0.889
aromatic compound catabolic process GO:0019439 491 0.735
ncrna processing GO:0034470 330 0.734
cellular nitrogen compound catabolic process GO:0044270 494 0.654
mrna metabolic process GO:0016071 269 0.468
heterocycle catabolic process GO:0046700 494 0.430
rna surveillance GO:0071025 30 0.425
nuclear polyadenylation dependent rrna catabolic process GO:0071035 18 0.392
macromolecule catabolic process GO:0009057 383 0.354
rna catabolic process GO:0006401 118 0.349
trna processing GO:0008033 101 0.319
cell communication GO:0007154 345 0.273
trna metabolic process GO:0006399 151 0.256
ribonucleoprotein complex assembly GO:0022618 143 0.239
snrna metabolic process GO:0016073 25 0.218
nucleobase containing compound catabolic process GO:0034655 479 0.213
ribosome biogenesis GO:0042254 335 0.212
nuclear mrna surveillance GO:0071028 22 0.195
rrna processing GO:0006364 227 0.192
nucleotide catabolic process GO:0009166 330 0.168
trna modification GO:0006400 75 0.147
single organism cellular localization GO:1902580 375 0.145
rrna catabolic process GO:0016075 31 0.139
actin filament based process GO:0030029 104 0.138
mrna catabolic process GO:0006402 93 0.134
regulation of molecular function GO:0065009 320 0.131
snorna processing GO:0043144 34 0.130
nuclear transcribed mrna catabolic process GO:0000956 89 0.130
double strand break repair GO:0006302 105 0.129
purine nucleotide metabolic process GO:0006163 376 0.128
single organism signaling GO:0044700 208 0.127
regulation of nuclear division GO:0051783 103 0.126
actin cytoskeleton organization GO:0030036 100 0.124
regulation of cellular component organization GO:0051128 334 0.120
snrna 3 end processing GO:0034472 16 0.120
nucleoside triphosphate catabolic process GO:0009143 329 0.112
organonitrogen compound catabolic process GO:1901565 404 0.111
meiotic cell cycle GO:0051321 272 0.107
organelle fission GO:0048285 272 0.106
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.102
ribonucleotide metabolic process GO:0009259 377 0.101
negative regulation of cellular metabolic process GO:0031324 407 0.100
snorna metabolic process GO:0016074 40 0.100
negative regulation of cellular component organization GO:0051129 109 0.099
ribonucleoprotein complex subunit organization GO:0071826 152 0.098
protein localization to organelle GO:0033365 337 0.098
nitrogen compound transport GO:0071705 212 0.098
organic cyclic compound catabolic process GO:1901361 499 0.096
purine nucleoside triphosphate metabolic process GO:0009144 356 0.094
establishment of protein localization to organelle GO:0072594 278 0.092
negative regulation of cellular biosynthetic process GO:0031327 312 0.089
regulation of organelle organization GO:0033043 243 0.087
negative regulation of macromolecule metabolic process GO:0010605 375 0.086
ribonucleotide catabolic process GO:0009261 327 0.086
regulation of protein modification process GO:0031399 110 0.086
cut catabolic process GO:0071034 12 0.085
purine ribonucleotide metabolic process GO:0009150 372 0.084
cell division GO:0051301 205 0.082
nuclear division GO:0000280 263 0.082
nucleoside metabolic process GO:0009116 394 0.082
protein localization to nucleus GO:0034504 74 0.081
carbohydrate derivative catabolic process GO:1901136 339 0.080
signaling GO:0023052 208 0.078
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.078
regulation of cell cycle process GO:0010564 150 0.077
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.076
regulation of transferase activity GO:0051338 83 0.076
purine nucleoside metabolic process GO:0042278 380 0.075
nucleoside phosphate catabolic process GO:1901292 331 0.072
purine ribonucleoside metabolic process GO:0046128 380 0.069
single organism catabolic process GO:0044712 619 0.069
regulation of phosphorus metabolic process GO:0051174 230 0.068
regulation of cell division GO:0051302 113 0.066
nucleoside triphosphate metabolic process GO:0009141 364 0.066
negative regulation of cell cycle process GO:0010948 86 0.065
purine nucleotide catabolic process GO:0006195 328 0.065
glycosyl compound metabolic process GO:1901657 398 0.064
ribosome assembly GO:0042255 57 0.063
nucleobase containing small molecule metabolic process GO:0055086 491 0.063
polyadenylation dependent rna catabolic process GO:0043633 22 0.063
maturation of lsu rrna GO:0000470 39 0.063
negative regulation of transcription dna templated GO:0045892 258 0.062
regulation of mitotic cell cycle GO:0007346 107 0.061
ribosomal large subunit biogenesis GO:0042273 98 0.059
response to abiotic stimulus GO:0009628 159 0.058
polyadenylation dependent ncrna catabolic process GO:0043634 20 0.056
maturation of 5 8s rrna GO:0000460 80 0.056
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000463 33 0.055
snrna processing GO:0016180 17 0.054
cellular protein complex disassembly GO:0043624 42 0.053
negative regulation of biosynthetic process GO:0009890 312 0.053
cellular macromolecule catabolic process GO:0044265 363 0.053
purine nucleoside triphosphate catabolic process GO:0009146 329 0.052
ncrna catabolic process GO:0034661 33 0.051
cellular response to chemical stimulus GO:0070887 315 0.051
cell cycle g1 s phase transition GO:0044843 64 0.051
response to external stimulus GO:0009605 158 0.050
regulation of meiotic cell cycle GO:0051445 43 0.050
nuclear transport GO:0051169 165 0.050
purine containing compound metabolic process GO:0072521 400 0.050
purine ribonucleotide catabolic process GO:0009154 327 0.049
phosphorylation GO:0016310 291 0.049
purine containing compound catabolic process GO:0072523 332 0.048
regulation of signaling GO:0023051 119 0.048
protein targeting GO:0006605 272 0.047
regulation of catalytic activity GO:0050790 307 0.047
regulation of phosphate metabolic process GO:0019220 230 0.046
protein dna complex assembly GO:0065004 105 0.046
rrna metabolic process GO:0016072 244 0.044
regulation of meiosis GO:0040020 42 0.044
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 80 0.043
ncrna 3 end processing GO:0043628 44 0.042
organelle localization GO:0051640 128 0.042
positive regulation of biosynthetic process GO:0009891 336 0.041
protein modification by small protein conjugation or removal GO:0070647 172 0.041
organophosphate catabolic process GO:0046434 338 0.041
negative regulation of rna metabolic process GO:0051253 262 0.041
regulation of cell communication GO:0010646 124 0.040
positive regulation of macromolecule metabolic process GO:0010604 394 0.040
negative regulation of nucleic acid templated transcription GO:1903507 260 0.040
regulation of localization GO:0032879 127 0.040
regulation of signal transduction GO:0009966 114 0.039
dna dependent dna replication GO:0006261 115 0.039
carbohydrate metabolic process GO:0005975 252 0.037
ion homeostasis GO:0050801 118 0.037
mitotic nuclear division GO:0007067 131 0.037
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.037
negative regulation of cell cycle GO:0045786 91 0.037
organophosphate metabolic process GO:0019637 597 0.036
intracellular protein transport GO:0006886 319 0.036
organic acid metabolic process GO:0006082 352 0.035
ribonucleoside monophosphate metabolic process GO:0009161 265 0.035
purine ribonucleoside catabolic process GO:0046130 330 0.035
rna 3 end processing GO:0031123 88 0.034
regulation of biological quality GO:0065008 391 0.034
cell wall organization GO:0071555 146 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.033
protein dna complex subunit organization GO:0071824 153 0.033
regulation of intracellular signal transduction GO:1902531 78 0.032
ribonucleoside triphosphate catabolic process GO:0009203 327 0.032
negative regulation of organelle organization GO:0010639 103 0.032
mrna processing GO:0006397 185 0.032
regulation of cellular catabolic process GO:0031329 195 0.031
modification dependent macromolecule catabolic process GO:0043632 203 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.031
carbohydrate derivative metabolic process GO:1901135 549 0.030
organic acid biosynthetic process GO:0016053 152 0.030
cation homeostasis GO:0055080 105 0.030
regulation of purine nucleotide catabolic process GO:0033121 106 0.030
nucleoside monophosphate metabolic process GO:0009123 267 0.030
vesicle mediated transport GO:0016192 335 0.030
negative regulation of gene expression GO:0010629 312 0.030
sexual reproduction GO:0019953 216 0.030
g1 s transition of mitotic cell cycle GO:0000082 64 0.029
mitotic cell cycle process GO:1903047 294 0.029
homeostatic process GO:0042592 227 0.029
regulation of catabolic process GO:0009894 199 0.029
meiotic cell cycle process GO:1903046 229 0.029
regulation of cellular localization GO:0060341 50 0.029
regulation of cell cycle GO:0051726 195 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.029
purine nucleoside catabolic process GO:0006152 330 0.028
glycosyl compound catabolic process GO:1901658 335 0.028
protein complex disassembly GO:0043241 70 0.027
reciprocal dna recombination GO:0035825 54 0.027
regulation of nucleotide catabolic process GO:0030811 106 0.027
response to starvation GO:0042594 96 0.026
mitotic cell cycle GO:0000278 306 0.026
purine nucleoside monophosphate catabolic process GO:0009128 224 0.026
cellular response to heat GO:0034605 53 0.026
negative regulation of catalytic activity GO:0043086 60 0.025
signal transduction GO:0007165 208 0.025
gene silencing GO:0016458 151 0.025
regulation of cellular protein metabolic process GO:0032268 232 0.025
negative regulation of molecular function GO:0044092 68 0.024
chemical homeostasis GO:0048878 137 0.024
ribonucleoside triphosphate metabolic process GO:0009199 356 0.024
ribose phosphate metabolic process GO:0019693 384 0.024
negative regulation of meiotic cell cycle GO:0051447 24 0.024
establishment of protein localization GO:0045184 367 0.024
poly a mrna export from nucleus GO:0016973 24 0.024
cell cycle dna replication GO:0044786 36 0.024
u4 snrna 3 end processing GO:0034475 11 0.024
response to nutrient levels GO:0031667 150 0.024
single organism membrane organization GO:0044802 275 0.024
regulation of protein metabolic process GO:0051246 237 0.023
dna strand elongation GO:0022616 29 0.023
positive regulation of rna metabolic process GO:0051254 294 0.023
protein transport GO:0015031 345 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.023
nucleoside monophosphate catabolic process GO:0009125 224 0.023
response to extracellular stimulus GO:0009991 156 0.023
single organism developmental process GO:0044767 258 0.022
regulation of hydrolase activity GO:0051336 133 0.022
reproductive process GO:0022414 248 0.022
dna replication initiation GO:0006270 48 0.022
guanosine containing compound catabolic process GO:1901069 109 0.022
ribonucleoside catabolic process GO:0042454 332 0.022
regulation of protein localization GO:0032880 62 0.022
regulation of nucleoside metabolic process GO:0009118 106 0.022
nuclear polyadenylation dependent ncrna catabolic process GO:0071046 20 0.021
cellular response to nutrient levels GO:0031669 144 0.021
response to organic cyclic compound GO:0014070 1 0.021
trna catabolic process GO:0016078 16 0.021
multi organism process GO:0051704 233 0.021
cellular developmental process GO:0048869 191 0.021
nucleoside phosphate metabolic process GO:0006753 458 0.021
intracellular signal transduction GO:0035556 112 0.021
membrane organization GO:0061024 276 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.021
fungal type cell wall organization GO:0031505 145 0.020
cellular component disassembly GO:0022411 86 0.020
dna conformation change GO:0071103 98 0.020
cellular amino acid metabolic process GO:0006520 225 0.020
multi organism reproductive process GO:0044703 216 0.020
double strand break repair via homologous recombination GO:0000724 54 0.020
regulation of transport GO:0051049 85 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.019
nucleoside catabolic process GO:0009164 335 0.019
ribonucleoside monophosphate catabolic process GO:0009158 224 0.019
single organism reproductive process GO:0044702 159 0.019
regulation of gene expression epigenetic GO:0040029 147 0.019
fungal type cell wall organization or biogenesis GO:0071852 169 0.018
regulation of gtp catabolic process GO:0033124 84 0.018
nucleotide metabolic process GO:0009117 453 0.018
meiotic dna double strand break formation GO:0042138 12 0.018
response to chemical GO:0042221 390 0.018
regulation of response to stimulus GO:0048583 157 0.018
regulation of protein phosphorylation GO:0001932 75 0.018
dephosphorylation GO:0016311 127 0.018
dna replication GO:0006260 147 0.018
positive regulation of catabolic process GO:0009896 135 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.017
positive regulation of cellular catabolic process GO:0031331 128 0.017
cellular response to starvation GO:0009267 90 0.017
protein modification by small protein removal GO:0070646 29 0.017
cellular response to dna damage stimulus GO:0006974 287 0.017
nuclear import GO:0051170 57 0.017
regulation of dna dependent dna replication initiation GO:0030174 21 0.017
cleavage involved in rrna processing GO:0000469 69 0.017
macromolecular complex disassembly GO:0032984 80 0.017
atp metabolic process GO:0046034 251 0.017
negative regulation of rna biosynthetic process GO:1902679 260 0.016
nucleocytoplasmic transport GO:0006913 163 0.016
cellular response to extracellular stimulus GO:0031668 150 0.016
oxoacid metabolic process GO:0043436 351 0.016
mrna splicing via spliceosome GO:0000398 108 0.016
regulation of purine nucleotide metabolic process GO:1900542 109 0.016
regulation of cell cycle phase transition GO:1901987 70 0.016
ribonucleoside metabolic process GO:0009119 389 0.016
cut metabolic process GO:0071043 12 0.016
mitotic cell cycle checkpoint GO:0007093 56 0.016
carboxylic acid metabolic process GO:0019752 338 0.016
cellular chemical homeostasis GO:0055082 123 0.015
cellular modified amino acid metabolic process GO:0006575 51 0.015
regulation of chromatin organization GO:1902275 23 0.015
death GO:0016265 30 0.015
pre replicative complex assembly GO:0036388 20 0.015
negative regulation of response to stimulus GO:0048585 40 0.014
positive regulation of transport GO:0051050 32 0.014
rna splicing via transesterification reactions GO:0000375 118 0.014
regulation of protein kinase activity GO:0045859 67 0.014
polyadenylation dependent snorna 3 end processing GO:0071051 8 0.014
positive regulation of molecular function GO:0044093 185 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.014
regulation of gtpase activity GO:0043087 84 0.014
nuclear polyadenylation dependent trna catabolic process GO:0071038 16 0.014
chromatin remodeling GO:0006338 80 0.014
endocytosis GO:0006897 90 0.014
cellular component morphogenesis GO:0032989 97 0.014
developmental process GO:0032502 261 0.014
translesion synthesis GO:0019985 16 0.013
protein localization to membrane GO:0072657 102 0.013
cell cycle phase transition GO:0044770 144 0.013
alpha amino acid biosynthetic process GO:1901607 91 0.013
response to osmotic stress GO:0006970 83 0.013
autophagy GO:0006914 106 0.012
meiosis i GO:0007127 92 0.012
positive regulation of cellular protein metabolic process GO:0032270 89 0.012
cellular response to oxidative stress GO:0034599 94 0.012
positive regulation of gene expression GO:0010628 321 0.012
detection of stimulus GO:0051606 4 0.012
apoptotic process GO:0006915 30 0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 109 0.012
oxidation reduction process GO:0055114 353 0.012
programmed cell death GO:0012501 30 0.012
organelle assembly GO:0070925 118 0.012
positive regulation of cell communication GO:0010647 28 0.012
gtp metabolic process GO:0046039 107 0.012
chromosome segregation GO:0007059 159 0.012
rna polyadenylation GO:0043631 26 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
negative regulation of signaling GO:0023057 30 0.012
reciprocal meiotic recombination GO:0007131 54 0.012
negative regulation of mitotic cell cycle GO:0045930 63 0.012
cellular response to organic substance GO:0071310 159 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 100 0.011
rna modification GO:0009451 99 0.011
leading strand elongation GO:0006272 9 0.011
dna recombination GO:0006310 172 0.011
ras protein signal transduction GO:0007265 29 0.011
protein import into nucleus GO:0006606 55 0.011
nuclear retention of pre mrna at the site of transcription GO:0071033 9 0.011
positive regulation of cellular biosynthetic process GO:0031328 336 0.010
protein complex assembly GO:0006461 302 0.010
snorna 3 end processing GO:0031126 21 0.010
meiotic nuclear division GO:0007126 163 0.010
nuclear mrna surveillance of mrna 3 end processing GO:0071031 7 0.010
nuclear ncrna surveillance GO:0071029 20 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.010
negative regulation of cell cycle phase transition GO:1901988 59 0.010
regulation of hormone levels GO:0010817 1 0.010

RAT1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org