Saccharomyces cerevisiae

146 known processes

LEO1 (YOR123C)

Leo1p

LEO1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transcription elongation from rna polymerase ii promoter GO:0006368 81 0.997
dna templated transcription elongation GO:0006354 91 0.986
chromatin organization GO:0006325 242 0.967
snorna metabolic process GO:0016074 40 0.887
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 38 0.832
positive regulation of dna templated transcription elongation GO:0032786 42 0.822
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 40 0.791
regulation of transcription from rna polymerase i promoter GO:0006356 36 0.734
dna recombination GO:0006310 172 0.731
transcription from rna polymerase i promoter GO:0006360 63 0.701
mrna metabolic process GO:0016071 269 0.677
histone modification GO:0016570 119 0.676
covalent chromatin modification GO:0016569 119 0.646
dna repair GO:0006281 236 0.629
regulation of dna templated transcription elongation GO:0032784 44 0.611
chromatin modification GO:0016568 200 0.607
regulation of chromatin organization GO:1902275 23 0.573
regulation of chromatin modification GO:1903308 23 0.551
chromatin silencing at telomere GO:0006348 84 0.511
histone lysine methylation GO:0034968 26 0.504
regulation of nucleotide excision repair GO:2000819 7 0.486
negative regulation of biosynthetic process GO:0009890 312 0.453
phosphorylation of rna polymerase ii c terminal domain GO:0070816 20 0.448
protein dna complex subunit organization GO:0071824 153 0.430
histone h3 k4 methylation GO:0051568 18 0.415
mrna processing GO:0006397 185 0.411
cellular response to dna damage stimulus GO:0006974 287 0.364
regulation of chromatin silencing at telomere GO:0031938 27 0.363
positive regulation of transcription from rna polymerase i promoter GO:0045943 19 0.361
transcription from rna polymerase iii promoter GO:0006383 40 0.347
protein methylation GO:0006479 48 0.342
peptidyl lysine modification GO:0018205 77 0.328
cellular amino acid metabolic process GO:0006520 225 0.327
organic acid metabolic process GO:0006082 352 0.327
methylation GO:0032259 101 0.325
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.315
negative regulation of cellular metabolic process GO:0031324 407 0.314
nucleosome organization GO:0034728 63 0.313
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.303
positive regulation of cellular biosynthetic process GO:0031328 336 0.274
chromatin silencing GO:0006342 147 0.273
mrna 3 end processing GO:0031124 54 0.270
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.270
macromolecule methylation GO:0043414 85 0.262
negative regulation of cellular biosynthetic process GO:0031327 312 0.260
negative regulation of nucleic acid templated transcription GO:1903507 260 0.259
regulation of chromatin silencing GO:0031935 39 0.257
peptidyl amino acid modification GO:0018193 116 0.255
chromatin assembly or disassembly GO:0006333 60 0.251
regulation of histone modification GO:0031056 18 0.249
regulation of dna repair GO:0006282 14 0.247
regulation of histone h2b ubiquitination GO:2001166 6 0.247
protein modification by small protein conjugation or removal GO:0070647 172 0.246
regulation of transcription coupled nucleotide excision repair GO:0090262 7 0.243
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.242
positive regulation of transcription elongation from rna polymerase i promoter GO:2001209 7 0.231
negative regulation of transcription dna templated GO:0045892 258 0.227
ribonucleoprotein complex subunit organization GO:0071826 152 0.225
histone ubiquitination GO:0016574 17 0.224
histone methylation GO:0016571 28 0.224
negative regulation of gene expression GO:0010629 312 0.221
protein alkylation GO:0008213 48 0.216
snorna processing GO:0043144 34 0.215
regulation of cellular ketone metabolic process GO:0010565 42 0.210
double strand break repair via nonhomologous end joining GO:0006303 27 0.205
dna templated transcription termination GO:0006353 42 0.204
positive regulation of transcription dna templated GO:0045893 286 0.199
regulation of chromosome organization GO:0033044 66 0.197
protein complex assembly GO:0006461 302 0.197
negative regulation of rna metabolic process GO:0051253 262 0.190
ncrna 3 end processing GO:0043628 44 0.189
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 19 0.174
non recombinational repair GO:0000726 33 0.164
regulation of protein metabolic process GO:0051246 237 0.163
protein complex biogenesis GO:0070271 314 0.162
positive regulation of gene expression GO:0010628 321 0.160
regulation of transcription elongation from rna polymerase i promoter GO:2001207 7 0.158
regulation of gene silencing GO:0060968 41 0.155
ribonucleoprotein complex assembly GO:0022618 143 0.151
positive regulation of protein metabolic process GO:0051247 93 0.145
transcription elongation from rna polymerase i promoter GO:0006362 10 0.144
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 51 0.142
internal protein amino acid acetylation GO:0006475 52 0.142
rna localization GO:0006403 112 0.142
negative regulation of rna biosynthetic process GO:1902679 260 0.141
regulation of response to dna damage stimulus GO:2001020 17 0.133
cellular amine metabolic process GO:0044106 51 0.132
nucleotide excision repair GO:0006289 50 0.132
regulation of dna metabolic process GO:0051052 100 0.130
oxoacid metabolic process GO:0043436 351 0.127
regulation of protein ubiquitination GO:0031396 20 0.125
protein modification by small protein conjugation GO:0032446 144 0.120
regulation of cellular component biogenesis GO:0044087 112 0.118
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 109 0.117
regulation of histone methylation GO:0031060 8 0.116
ribosome biogenesis GO:0042254 335 0.115
phosphorylation of rna polymerase ii c terminal domain serine 2 residues GO:0071619 4 0.114
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.112
positive regulation of biosynthetic process GO:0009891 336 0.112
single organism cellular localization GO:1902580 375 0.108
protein ubiquitination GO:0016567 118 0.107
transcription coupled nucleotide excision repair GO:0006283 16 0.102
regulation of histone h2b conserved c terminal lysine ubiquitination GO:2001173 5 0.101
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.099
negative regulation of gene expression epigenetic GO:0045814 147 0.096
regulation of cellular amine metabolic process GO:0033238 21 0.096
carboxylic acid metabolic process GO:0019752 338 0.094
amine metabolic process GO:0009308 51 0.093
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.089
positive regulation of phosphorus metabolic process GO:0010562 147 0.086
cellular ketone metabolic process GO:0042180 63 0.084
regulation of transcription by chromatin organization GO:0034401 19 0.084
rna export from nucleus GO:0006405 88 0.083
regulation of phosphorylation of rna polymerase ii c terminal domain serine 2 residues GO:2001163 4 0.083
chromatin remodeling GO:0006338 80 0.077
protein dna complex assembly GO:0065004 105 0.077
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 11 0.076
regulation of protein complex assembly GO:0043254 77 0.074
histone h2b conserved c terminal lysine ubiquitination GO:0071894 6 0.073
positive regulation of cellular component organization GO:0051130 116 0.072
phosphorylation GO:0016310 291 0.072
regulation of biological quality GO:0065008 391 0.070
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 13 0.070
cellular response to chemical stimulus GO:0070887 315 0.069
peptidyl lysine acetylation GO:0018394 52 0.069
regulation of phosphorylation of rna polymerase ii c terminal domain GO:1901407 5 0.068
positive regulation of rna metabolic process GO:0051254 294 0.068
ncrna processing GO:0034470 330 0.066
negative regulation of macromolecule metabolic process GO:0010605 375 0.066
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.063
gene silencing GO:0016458 151 0.063
mrna splicing via spliceosome GO:0000398 108 0.063
macromolecular complex disassembly GO:0032984 80 0.061
positive regulation of cellular protein metabolic process GO:0032270 89 0.061
positive regulation of macromolecule metabolic process GO:0010604 394 0.060
cellular component disassembly GO:0022411 86 0.059
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.056
regulation of cellular protein metabolic process GO:0032268 232 0.055
regulation of histone ubiquitination GO:0033182 7 0.054
protein complex disassembly GO:0043241 70 0.053
regulation of cellular amino acid metabolic process GO:0006521 16 0.051
rna transport GO:0050658 92 0.050
protein acetylation GO:0006473 59 0.049
regulation of gene expression epigenetic GO:0040029 147 0.049
regulation of organelle organization GO:0033043 243 0.048
rna 3 end processing GO:0031123 88 0.048
nucleic acid transport GO:0050657 94 0.045
regulation of cellular response to stress GO:0080135 50 0.043
transcription initiation from rna polymerase ii promoter GO:0006367 55 0.043
regulation of cellular component organization GO:0051128 334 0.043
cellular developmental process GO:0048869 191 0.043
response to external stimulus GO:0009605 158 0.042
dna templated transcriptional preinitiation complex assembly GO:0070897 51 0.042
positive regulation of chromatin modification GO:1903310 13 0.041
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.041
positive regulation of protein modification process GO:0031401 49 0.040
regulation of histone h3 k4 methylation GO:0051569 5 0.040
peptidyl lysine methylation GO:0018022 24 0.039
protein acylation GO:0043543 66 0.039
histone acetylation GO:0016573 51 0.039
regulation of dna templated transcription in response to stress GO:0043620 51 0.038
establishment of protein localization GO:0045184 367 0.038
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.038
response to osmotic stress GO:0006970 83 0.036
histone exchange GO:0043486 18 0.035
negative regulation of dna metabolic process GO:0051053 36 0.033
rrna processing GO:0006364 227 0.033
atp dependent chromatin remodeling GO:0043044 36 0.032
posttranscriptional regulation of gene expression GO:0010608 115 0.032
chromatin silencing at silent mating type cassette GO:0030466 53 0.032
dna replication GO:0006260 147 0.032
positive regulation of phosphate metabolic process GO:0045937 147 0.031
nuclear export GO:0051168 124 0.030
positive regulation of cellular amine metabolic process GO:0033240 10 0.030
regulation of protein modification by small protein conjugation or removal GO:1903320 29 0.030
nucleobase containing compound transport GO:0015931 124 0.029
internal peptidyl lysine acetylation GO:0018393 52 0.029
chromatin assembly GO:0031497 35 0.028
positive regulation of histone modification GO:0031058 12 0.027
cell differentiation GO:0030154 161 0.027
chromatin silencing at rdna GO:0000183 32 0.027
regulation of protein modification process GO:0031399 110 0.027
response to nutrient levels GO:0031667 150 0.026
regulation of transcription from rna polymerase iii promoter GO:0006359 16 0.026
positive regulation of organelle organization GO:0010638 85 0.026
cellular response to nutrient GO:0031670 50 0.025
positive regulation of phosphorylation of rna polymerase ii c terminal domain GO:1901409 4 0.025
protein targeting GO:0006605 272 0.025
positive regulation of protein phosphorylation GO:0001934 28 0.024
cell communication GO:0007154 345 0.024
cellular response to external stimulus GO:0071496 150 0.024
positive regulation of protein complex assembly GO:0031334 39 0.024
response to extracellular stimulus GO:0009991 156 0.024
dna replication independent nucleosome organization GO:0034724 9 0.023
cellular response to extracellular stimulus GO:0031668 150 0.023
carbohydrate derivative biosynthetic process GO:1901137 181 0.023
response to abiotic stimulus GO:0009628 159 0.022
macromolecule catabolic process GO:0009057 383 0.022
regulation of dna templated transcription initiation GO:2000142 19 0.021
single organism catabolic process GO:0044712 619 0.021
regulation of response to stress GO:0080134 57 0.021
regulation of response to stimulus GO:0048583 157 0.021
nucleocytoplasmic transport GO:0006913 163 0.021
protein deubiquitination GO:0016579 17 0.020
protein phosphorylation GO:0006468 197 0.020
rrna metabolic process GO:0016072 244 0.019
purine nucleoside triphosphate catabolic process GO:0009146 329 0.019
mitotic cell cycle phase transition GO:0044772 141 0.019
nucleosome assembly GO:0006334 16 0.018
establishment of rna localization GO:0051236 92 0.018
mitotic cell cycle process GO:1903047 294 0.018
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.018
rna phosphodiester bond hydrolysis GO:0090501 112 0.018
peptidyl lysine trimethylation GO:0018023 8 0.017
transposition GO:0032196 20 0.017
carbohydrate metabolic process GO:0005975 252 0.017
protein transport GO:0015031 345 0.016
positive regulation of nucleic acid templated transcription GO:1903508 286 0.016
heterochromatin organization GO:0070828 11 0.016
positive regulation of phosphorylation GO:0042327 33 0.016
termination of rna polymerase ii transcription GO:0006369 26 0.016
snorna 3 end processing GO:0031126 21 0.016
positive regulation of rna biosynthetic process GO:1902680 286 0.016
regulation of phosphate metabolic process GO:0019220 230 0.015
mrna transport GO:0051028 60 0.014
glycosyl compound metabolic process GO:1901657 398 0.014
positive regulation of chromosome organization GO:2001252 20 0.014
mrna export from nucleus GO:0006406 60 0.014
dna conformation change GO:0071103 98 0.014
anatomical structure homeostasis GO:0060249 74 0.014
nucleosome disassembly GO:0006337 19 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 7 0.013
poly a mrna export from nucleus GO:0016973 24 0.013
regulation of translation GO:0006417 89 0.013
rna splicing GO:0008380 131 0.013
nucleobase containing small molecule metabolic process GO:0055086 491 0.013
protein targeting to vacuole GO:0006623 91 0.013
regulation of histone exchange GO:1900049 4 0.013
positive regulation of carbohydrate metabolic process GO:0045913 13 0.013
dna dependent dna replication GO:0006261 115 0.012
reciprocal meiotic recombination GO:0007131 54 0.012
response to topologically incorrect protein GO:0035966 38 0.012
establishment of protein localization to organelle GO:0072594 278 0.012
establishment or maintenance of cell polarity GO:0007163 96 0.012
mitotic cell cycle GO:0000278 306 0.012
regulation of dna recombination GO:0000018 24 0.012
positive regulation of apoptotic process GO:0043065 3 0.012
anatomical structure formation involved in morphogenesis GO:0048646 136 0.012
dna strand elongation involved in dna replication GO:0006271 26 0.012
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 13 0.012
regulation of phosphorus metabolic process GO:0051174 230 0.012
gene silencing by rna GO:0031047 3 0.012
organophosphate metabolic process GO:0019637 597 0.012
small molecule biosynthetic process GO:0044283 258 0.011
purine ribonucleoside catabolic process GO:0046130 330 0.011
protein import GO:0017038 122 0.011
negative regulation of transcription from rna polymerase i promoter GO:0016479 8 0.011
single organism developmental process GO:0044767 258 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.011
positive regulation of molecular function GO:0044093 185 0.011
chromosome segregation GO:0007059 159 0.011
generation of precursor metabolites and energy GO:0006091 147 0.010
transcription initiation from rna polymerase iii promoter GO:0006384 16 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.010
nucleotide metabolic process GO:0009117 453 0.010
response to nutrient GO:0007584 52 0.010
carbohydrate derivative metabolic process GO:1901135 549 0.010
cellular response to organic substance GO:0071310 159 0.010
protein catabolic process GO:0030163 221 0.010
ribose phosphate metabolic process GO:0019693 384 0.010
nitrogen compound transport GO:0071705 212 0.010
translational initiation GO:0006413 56 0.010
aromatic compound catabolic process GO:0019439 491 0.010
transposition rna mediated GO:0032197 17 0.010

LEO1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org