Saccharomyces cerevisiae

43 known processes

MLH3 (YPL164C)

Mlh3p

MLH3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic cell cycle GO:0051321 272 0.953
meiotic cell cycle process GO:1903046 229 0.911
meiosis i GO:0007127 92 0.679
meiotic nuclear division GO:0007126 163 0.580
nuclear division GO:0000280 263 0.496
organelle fission GO:0048285 272 0.416
cellular response to dna damage stimulus GO:0006974 287 0.363
dna repair GO:0006281 236 0.270
dna recombination GO:0006310 172 0.256
reproductive process in single celled organism GO:0022413 145 0.240
reciprocal dna recombination GO:0035825 54 0.236
sexual reproduction GO:0019953 216 0.223
synapsis GO:0007129 19 0.220
reproduction of a single celled organism GO:0032505 191 0.220
reproductive process GO:0022414 248 0.170
multi organism reproductive process GO:0044703 216 0.137
negative regulation of macromolecule metabolic process GO:0010605 375 0.133
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.123
macromolecule catabolic process GO:0009057 383 0.119
nucleobase containing compound catabolic process GO:0034655 479 0.117
fungal type cell wall organization GO:0031505 145 0.113
anatomical structure morphogenesis GO:0009653 160 0.107
positive regulation of gene expression GO:0010628 321 0.106
reciprocal meiotic recombination GO:0007131 54 0.101
cellular nitrogen compound catabolic process GO:0044270 494 0.100
heterocycle catabolic process GO:0046700 494 0.094
carboxylic acid metabolic process GO:0019752 338 0.093
fatty acid metabolic process GO:0006631 51 0.092
protein complex biogenesis GO:0070271 314 0.091
negative regulation of transcription dna templated GO:0045892 258 0.091
negative regulation of cellular metabolic process GO:0031324 407 0.091
sporulation GO:0043934 132 0.085
organic acid metabolic process GO:0006082 352 0.085
positive regulation of rna metabolic process GO:0051254 294 0.083
cellular macromolecule catabolic process GO:0044265 363 0.082
sexual sporulation GO:0034293 113 0.080
cell cycle phase transition GO:0044770 144 0.079
single organism cellular localization GO:1902580 375 0.075
carbohydrate derivative metabolic process GO:1901135 549 0.074
negative regulation of gene expression GO:0010629 312 0.073
cellular developmental process GO:0048869 191 0.072
nucleobase containing small molecule metabolic process GO:0055086 491 0.070
dna conformation change GO:0071103 98 0.070
glycosyl compound metabolic process GO:1901657 398 0.068
oxoacid metabolic process GO:0043436 351 0.068
chromosome organization involved in meiosis GO:0070192 32 0.068
external encapsulating structure organization GO:0045229 146 0.067
purine nucleoside metabolic process GO:0042278 380 0.065
multi organism process GO:0051704 233 0.065
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.064
developmental process involved in reproduction GO:0003006 159 0.063
rna 3 end processing GO:0031123 88 0.062
positive regulation of rna biosynthetic process GO:1902680 286 0.062
single organism reproductive process GO:0044702 159 0.061
ribonucleoside metabolic process GO:0009119 389 0.061
sporulation resulting in formation of a cellular spore GO:0030435 129 0.061
cytoskeleton organization GO:0007010 230 0.061
nucleoside triphosphate metabolic process GO:0009141 364 0.060
cellular lipid metabolic process GO:0044255 229 0.058
intracellular signal transduction GO:0035556 112 0.058
developmental process GO:0032502 261 0.055
cell wall organization or biogenesis GO:0071554 190 0.054
anatomical structure formation involved in morphogenesis GO:0048646 136 0.054
regulation of protein metabolic process GO:0051246 237 0.054
regulation of cellular protein metabolic process GO:0032268 232 0.051
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.050
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.050
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.050
ascospore wall biogenesis GO:0070591 52 0.049
chromatin organization GO:0006325 242 0.049
filamentous growth GO:0030447 124 0.049
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.049
translation GO:0006412 230 0.049
signal transduction GO:0007165 208 0.049
double strand break repair GO:0006302 105 0.049
telomere maintenance GO:0000723 74 0.048
aromatic compound catabolic process GO:0019439 491 0.046
mitotic sister chromatid segregation GO:0000070 85 0.045
cell growth GO:0016049 89 0.045
single organism developmental process GO:0044767 258 0.044
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.043
response to chemical GO:0042221 390 0.043
regulation of phosphate metabolic process GO:0019220 230 0.043
sister chromatid segregation GO:0000819 93 0.043
ribose phosphate metabolic process GO:0019693 384 0.042
ribonucleoside monophosphate metabolic process GO:0009161 265 0.042
cell wall organization GO:0071555 146 0.042
nucleoside catabolic process GO:0009164 335 0.041
negative regulation of rna metabolic process GO:0051253 262 0.041
positive regulation of cellular biosynthetic process GO:0031328 336 0.041
response to organic substance GO:0010033 182 0.040
fungal type cell wall organization or biogenesis GO:0071852 169 0.040
phosphorylation GO:0016310 291 0.040
response to organic cyclic compound GO:0014070 1 0.039
purine ribonucleotide metabolic process GO:0009150 372 0.039
protein phosphorylation GO:0006468 197 0.039
mitotic cell cycle phase transition GO:0044772 141 0.039
chromosome segregation GO:0007059 159 0.038
negative regulation of rna biosynthetic process GO:1902679 260 0.038
negative regulation of biosynthetic process GO:0009890 312 0.038
regulation of cellular ketone metabolic process GO:0010565 42 0.038
cellular response to chemical stimulus GO:0070887 315 0.037
purine ribonucleoside metabolic process GO:0046128 380 0.037
nucleoside phosphate metabolic process GO:0006753 458 0.037
lipid metabolic process GO:0006629 269 0.036
regulation of nuclear division GO:0051783 103 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.036
positive regulation of nucleic acid templated transcription GO:1903508 286 0.036
regulation of cell cycle process GO:0010564 150 0.036
chromatin silencing GO:0006342 147 0.035
negative regulation of cellular biosynthetic process GO:0031327 312 0.035
organelle localization GO:0051640 128 0.034
purine nucleoside triphosphate metabolic process GO:0009144 356 0.034
protein complex assembly GO:0006461 302 0.033
ribonucleoside catabolic process GO:0042454 332 0.033
mitochondrion organization GO:0007005 261 0.033
organophosphate metabolic process GO:0019637 597 0.033
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.033
response to heat GO:0009408 69 0.032
organic cyclic compound catabolic process GO:1901361 499 0.032
regulation of biological quality GO:0065008 391 0.032
double strand break repair via nonhomologous end joining GO:0006303 27 0.031
purine nucleotide metabolic process GO:0006163 376 0.031
purine containing compound metabolic process GO:0072521 400 0.031
regulation of catalytic activity GO:0050790 307 0.030
nucleotide metabolic process GO:0009117 453 0.030
signaling GO:0023052 208 0.029
purine ribonucleoside catabolic process GO:0046130 330 0.029
positive regulation of cellular protein metabolic process GO:0032270 89 0.029
protein localization to organelle GO:0033365 337 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.029
positive regulation of protein modification process GO:0031401 49 0.028
regulation of protein modification process GO:0031399 110 0.028
positive regulation of macromolecule metabolic process GO:0010604 394 0.028
ribonucleoside triphosphate metabolic process GO:0009199 356 0.028
negative regulation of nucleic acid templated transcription GO:1903507 260 0.028
single organism signaling GO:0044700 208 0.028
cellular response to abiotic stimulus GO:0071214 62 0.028
regulation of mitotic cell cycle phase transition GO:1901990 68 0.028
telomere organization GO:0032200 75 0.027
organophosphate catabolic process GO:0046434 338 0.027
protein import GO:0017038 122 0.027
modification dependent macromolecule catabolic process GO:0043632 203 0.027
lipid catabolic process GO:0016042 33 0.027
nucleoside metabolic process GO:0009116 394 0.027
purine nucleoside catabolic process GO:0006152 330 0.026
regulation of gene expression epigenetic GO:0040029 147 0.026
organelle assembly GO:0070925 118 0.026
regulation of cell cycle GO:0051726 195 0.026
organonitrogen compound catabolic process GO:1901565 404 0.026
growth GO:0040007 157 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.025
vesicle mediated transport GO:0016192 335 0.025
proteolysis GO:0006508 268 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.025
single organism catabolic process GO:0044712 619 0.025
regulation of cell division GO:0051302 113 0.025
fatty acid catabolic process GO:0009062 17 0.024
regulation of cellular component organization GO:0051128 334 0.024
purine containing compound catabolic process GO:0072523 332 0.024
nucleotide excision repair GO:0006289 50 0.024
negative regulation of cellular protein metabolic process GO:0032269 85 0.024
cell communication GO:0007154 345 0.024
negative regulation of protein metabolic process GO:0051248 85 0.024
establishment of organelle localization GO:0051656 96 0.024
replicative cell aging GO:0001302 46 0.023
carboxylic acid biosynthetic process GO:0046394 152 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.023
response to abiotic stimulus GO:0009628 159 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.023
chromatin modification GO:0016568 200 0.022
generation of precursor metabolites and energy GO:0006091 147 0.022
positive regulation of transcription dna templated GO:0045893 286 0.022
rna catabolic process GO:0006401 118 0.022
homeostatic process GO:0042592 227 0.022
positive regulation of protein metabolic process GO:0051247 93 0.022
cellular response to external stimulus GO:0071496 150 0.022
cellular protein complex assembly GO:0043623 209 0.021
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.021
mitotic cell cycle GO:0000278 306 0.021
regulation of cellular catabolic process GO:0031329 195 0.021
glycosyl compound catabolic process GO:1901658 335 0.021
purine nucleoside monophosphate metabolic process GO:0009126 262 0.020
single organism membrane organization GO:0044802 275 0.020
ribonucleotide metabolic process GO:0009259 377 0.020
ribonucleoside monophosphate catabolic process GO:0009158 224 0.020
atp catabolic process GO:0006200 224 0.020
cell aging GO:0007569 70 0.020
regulation of catabolic process GO:0009894 199 0.020
regulation of molecular function GO:0065009 320 0.020
mrna 3 end processing GO:0031124 54 0.020
ribonucleoside triphosphate catabolic process GO:0009203 327 0.020
mitotic nuclear division GO:0007067 131 0.020
spore wall biogenesis GO:0070590 52 0.020
nucleoside triphosphate catabolic process GO:0009143 329 0.020
dna integrity checkpoint GO:0031570 41 0.020
non recombinational repair GO:0000726 33 0.019
atp metabolic process GO:0046034 251 0.019
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 51 0.019
regulation of translation GO:0006417 89 0.019
response to osmotic stress GO:0006970 83 0.019
response to oxidative stress GO:0006979 99 0.019
dna replication GO:0006260 147 0.019
covalent chromatin modification GO:0016569 119 0.019
microtubule cytoskeleton organization GO:0000226 109 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.019
protein catabolic process GO:0030163 221 0.019
cellular response to osmotic stress GO:0071470 50 0.019
cellular component morphogenesis GO:0032989 97 0.018
organonitrogen compound biosynthetic process GO:1901566 314 0.018
carbohydrate derivative catabolic process GO:1901136 339 0.018
organic acid catabolic process GO:0016054 71 0.018
regulation of phosphorus metabolic process GO:0051174 230 0.018
dna packaging GO:0006323 55 0.018
positive regulation of catalytic activity GO:0043085 178 0.018
regulation of dna templated transcription in response to stress GO:0043620 51 0.018
regulation of dna metabolic process GO:0051052 100 0.018
purine nucleotide catabolic process GO:0006195 328 0.018
ribonucleotide catabolic process GO:0009261 327 0.017
mitotic cell cycle process GO:1903047 294 0.017
response to temperature stimulus GO:0009266 74 0.017
small molecule catabolic process GO:0044282 88 0.017
nucleoside monophosphate metabolic process GO:0009123 267 0.017
cellular amino acid metabolic process GO:0006520 225 0.017
purine nucleoside triphosphate catabolic process GO:0009146 329 0.017
cell development GO:0048468 107 0.017
organic acid biosynthetic process GO:0016053 152 0.017
purine ribonucleotide catabolic process GO:0009154 327 0.017
chemical homeostasis GO:0048878 137 0.016
positive regulation of biosynthetic process GO:0009891 336 0.016
positive regulation of phosphorus metabolic process GO:0010562 147 0.016
transmembrane transport GO:0055085 349 0.016
regulation of hydrolase activity GO:0051336 133 0.015
cellular protein catabolic process GO:0044257 213 0.015
regulation of response to stress GO:0080134 57 0.015
protein modification by small protein conjugation or removal GO:0070647 172 0.015
conjugation with cellular fusion GO:0000747 106 0.015
cellular response to organic substance GO:0071310 159 0.015
fungal type cell wall assembly GO:0071940 53 0.015
negative regulation of cellular component organization GO:0051129 109 0.015
membrane organization GO:0061024 276 0.015
lipid biosynthetic process GO:0008610 170 0.015
spindle organization GO:0007051 37 0.015
regulation of response to stimulus GO:0048583 157 0.014
posttranscriptional regulation of gene expression GO:0010608 115 0.014
cellular amine metabolic process GO:0044106 51 0.014
anatomical structure development GO:0048856 160 0.014
cellular lipid catabolic process GO:0044242 33 0.014
negative regulation of phosphate metabolic process GO:0045936 49 0.014
regulation of cell cycle phase transition GO:1901987 70 0.014
cellular response to oxidative stress GO:0034599 94 0.014
regulation of cell communication GO:0010646 124 0.014
regulation of phosphorylation GO:0042325 86 0.014
glycerophospholipid metabolic process GO:0006650 98 0.014
regulation of lipid catabolic process GO:0050994 4 0.013
multi organism cellular process GO:0044764 120 0.013
positive regulation of hydrolase activity GO:0051345 112 0.013
regulation of growth of unicellular organism as a thread of attached cells GO:0070784 31 0.013
response to extracellular stimulus GO:0009991 156 0.013
nuclear transcribed mrna catabolic process GO:0000956 89 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.013
regulation of protein phosphorylation GO:0001932 75 0.013
positive regulation of apoptotic process GO:0043065 3 0.013
regulation of cellular response to stress GO:0080135 50 0.013
response to endogenous stimulus GO:0009719 26 0.012
nucleoside phosphate catabolic process GO:1901292 331 0.012
carbohydrate derivative biosynthetic process GO:1901137 181 0.012
positive regulation of catabolic process GO:0009896 135 0.012
pseudohyphal growth GO:0007124 75 0.012
cellular modified amino acid metabolic process GO:0006575 51 0.012
negative regulation of cell cycle phase transition GO:1901988 59 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.012
nucleoside monophosphate catabolic process GO:0009125 224 0.012
positive regulation of cellular catabolic process GO:0031331 128 0.012
gene silencing GO:0016458 151 0.012
regulation of anatomical structure size GO:0090066 50 0.012
apoptotic process GO:0006915 30 0.012
ascospore formation GO:0030437 107 0.012
aerobic respiration GO:0009060 55 0.012
rrna metabolic process GO:0016072 244 0.012
ribosome biogenesis GO:0042254 335 0.012
cellular response to extracellular stimulus GO:0031668 150 0.012
lipid modification GO:0030258 37 0.012
phospholipid biosynthetic process GO:0008654 89 0.012
mitotic cell cycle checkpoint GO:0007093 56 0.012
mrna processing GO:0006397 185 0.011
positive regulation of organelle organization GO:0010638 85 0.011
regulation of dna recombination GO:0000018 24 0.011
filamentous growth of a population of unicellular organisms GO:0044182 109 0.011
chromosome separation GO:0051304 33 0.011
protein targeting GO:0006605 272 0.011
regulation of mitotic cell cycle GO:0007346 107 0.011
regulation of lipid biosynthetic process GO:0046890 32 0.011
microtubule based process GO:0007017 117 0.011
cell morphogenesis GO:0000902 30 0.011
cellular ketone metabolic process GO:0042180 63 0.011
mrna metabolic process GO:0016071 269 0.011
nuclear transport GO:0051169 165 0.011
ubiquitin dependent protein catabolic process GO:0006511 181 0.011
dna catabolic process GO:0006308 42 0.011
histone modification GO:0016570 119 0.011
alcohol biosynthetic process GO:0046165 75 0.011
negative regulation of mitotic cell cycle GO:0045930 63 0.011
negative regulation of cell cycle process GO:0010948 86 0.011
intracellular protein transport GO:0006886 319 0.011
synaptonemal complex assembly GO:0007130 12 0.011
anatomical structure homeostasis GO:0060249 74 0.010
positive regulation of molecular function GO:0044093 185 0.010
protein transport GO:0015031 345 0.010
fungal type cell wall biogenesis GO:0009272 80 0.010
cell wall assembly GO:0070726 54 0.010
regulation of lipid metabolic process GO:0019216 45 0.010
dephosphorylation GO:0016311 127 0.010
peroxisome organization GO:0007031 68 0.010
cellular respiration GO:0045333 82 0.010
positive regulation of fatty acid oxidation GO:0046321 3 0.010
rna localization GO:0006403 112 0.010
amine metabolic process GO:0009308 51 0.010
cell differentiation GO:0030154 161 0.010
regulation of cellular component biogenesis GO:0044087 112 0.010

MLH3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029