Saccharomyces cerevisiae

72 known processes

PCL8 (YPL219W)

Pcl8p

PCL8 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
generation of precursor metabolites and energy GO:0006091 147 0.617
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.430
energy derivation by oxidation of organic compounds GO:0015980 125 0.351
cellular response to starvation GO:0009267 90 0.346
macroautophagy GO:0016236 55 0.312
cellular response to extracellular stimulus GO:0031668 150 0.310
protein phosphorylation GO:0006468 197 0.296
negative regulation of cellular metabolic process GO:0031324 407 0.282
cellular response to external stimulus GO:0071496 150 0.271
oxidation reduction process GO:0055114 353 0.269
lipid biosynthetic process GO:0008610 170 0.253
regulation of molecular function GO:0065009 320 0.231
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.224
response to chemical GO:0042221 390 0.211
glucan biosynthetic process GO:0009250 26 0.197
membrane organization GO:0061024 276 0.193
negative regulation of macromolecule metabolic process GO:0010605 375 0.188
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.188
mitochondrial transport GO:0006839 76 0.182
response to nutrient levels GO:0031667 150 0.173
regulation of response to extracellular stimulus GO:0032104 20 0.172
response to extracellular stimulus GO:0009991 156 0.171
response to starvation GO:0042594 96 0.157
regulation of biological quality GO:0065008 391 0.150
response to abiotic stimulus GO:0009628 159 0.149
negative regulation of biosynthetic process GO:0009890 312 0.147
single organism membrane organization GO:0044802 275 0.142
regulation of response to nutrient levels GO:0032107 20 0.141
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.139
energy reserve metabolic process GO:0006112 32 0.134
autophagy GO:0006914 106 0.133
regulation of cellular protein metabolic process GO:0032268 232 0.133
single organism cellular localization GO:1902580 375 0.130
cellular carbohydrate biosynthetic process GO:0034637 49 0.127
cellular polysaccharide biosynthetic process GO:0033692 38 0.124
cell communication GO:0007154 345 0.119
regulation of macroautophagy GO:0016241 15 0.117
negative regulation of transcription dna templated GO:0045892 258 0.117
cellular response to chemical stimulus GO:0070887 315 0.113
positive regulation of macromolecule metabolic process GO:0010604 394 0.111
regulation of autophagy GO:0010506 18 0.109
regulation of cellular component organization GO:0051128 334 0.105
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.104
translation GO:0006412 230 0.098
regulation of cellular response to stress GO:0080135 50 0.097
single organism carbohydrate metabolic process GO:0044723 237 0.095
intracellular protein transport GO:0006886 319 0.092
cellular response to nutrient levels GO:0031669 144 0.089
negative regulation of rna biosynthetic process GO:1902679 260 0.089
nuclear transport GO:0051169 165 0.089
negative regulation of gene expression GO:0010629 312 0.089
phosphorylation GO:0016310 291 0.086
monosaccharide metabolic process GO:0005996 83 0.084
cellular glucan metabolic process GO:0006073 44 0.083
purine ribonucleoside metabolic process GO:0046128 380 0.083
regulation of protein modification process GO:0031399 110 0.082
cellular carbohydrate metabolic process GO:0044262 135 0.080
glucan metabolic process GO:0044042 44 0.078
chemical homeostasis GO:0048878 137 0.077
mitotic cell cycle GO:0000278 306 0.077
protein targeting GO:0006605 272 0.076
reproductive process GO:0022414 248 0.076
sexual reproduction GO:0019953 216 0.076
cellular response to dna damage stimulus GO:0006974 287 0.075
regulation of catalytic activity GO:0050790 307 0.073
regulation of cellular catabolic process GO:0031329 195 0.072
mitotic cell cycle phase transition GO:0044772 141 0.071
negative regulation of rna metabolic process GO:0051253 262 0.071
polysaccharide metabolic process GO:0005976 60 0.071
carboxylic acid metabolic process GO:0019752 338 0.067
response to temperature stimulus GO:0009266 74 0.066
homeostatic process GO:0042592 227 0.066
regulation of response to external stimulus GO:0032101 20 0.065
regulation of phosphate metabolic process GO:0019220 230 0.065
positive regulation of protein metabolic process GO:0051247 93 0.065
carbohydrate biosynthetic process GO:0016051 82 0.063
lipid metabolic process GO:0006629 269 0.063
single organism catabolic process GO:0044712 619 0.063
glucose metabolic process GO:0006006 65 0.062
regulation of response to stress GO:0080134 57 0.062
regulation of protein kinase activity GO:0045859 67 0.061
glycogen metabolic process GO:0005977 30 0.061
regulation of glycogen biosynthetic process GO:0005979 9 0.061
regulation of protein metabolic process GO:0051246 237 0.059
carbohydrate metabolic process GO:0005975 252 0.055
response to external stimulus GO:0009605 158 0.055
carbohydrate derivative biosynthetic process GO:1901137 181 0.055
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.054
nitrogen compound transport GO:0071705 212 0.053
filamentous growth GO:0030447 124 0.052
carboxylic acid biosynthetic process GO:0046394 152 0.052
purine containing compound metabolic process GO:0072521 400 0.051
establishment or maintenance of cell polarity GO:0007163 96 0.051
regulation of catabolic process GO:0009894 199 0.049
regulation of phosphorus metabolic process GO:0051174 230 0.049
gene silencing GO:0016458 151 0.049
cell cycle phase transition GO:0044770 144 0.048
positive regulation of gene expression GO:0010628 321 0.048
negative regulation of nucleic acid templated transcription GO:1903507 260 0.047
nucleocytoplasmic transport GO:0006913 163 0.047
regulation of lipid metabolic process GO:0019216 45 0.046
negative regulation of cellular biosynthetic process GO:0031327 312 0.045
regulation of cell cycle GO:0051726 195 0.045
cell growth GO:0016049 89 0.045
multi organism reproductive process GO:0044703 216 0.044
multi organism cellular process GO:0044764 120 0.044
cation homeostasis GO:0055080 105 0.043
pseudohyphal growth GO:0007124 75 0.043
cellular cation homeostasis GO:0030003 100 0.043
regulation of cell communication GO:0010646 124 0.043
response to pheromone GO:0019236 92 0.042
single organism signaling GO:0044700 208 0.041
cellular homeostasis GO:0019725 138 0.040
monocarboxylic acid metabolic process GO:0032787 122 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.040
regulation of organelle organization GO:0033043 243 0.040
glycosyl compound biosynthetic process GO:1901659 42 0.040
response to oxidative stress GO:0006979 99 0.040
nucleoside phosphate metabolic process GO:0006753 458 0.039
mitotic cell cycle process GO:1903047 294 0.038
response to heat GO:0009408 69 0.037
atp metabolic process GO:0046034 251 0.036
chromatin silencing GO:0006342 147 0.036
filamentous growth of a population of unicellular organisms GO:0044182 109 0.035
chromatin modification GO:0016568 200 0.035
organophosphate metabolic process GO:0019637 597 0.034
carbohydrate derivative metabolic process GO:1901135 549 0.034
regulation of localization GO:0032879 127 0.033
transmembrane transport GO:0055085 349 0.033
response to inorganic substance GO:0010035 47 0.033
nuclear export GO:0051168 124 0.032
cellular chemical homeostasis GO:0055082 123 0.032
dna dependent dna replication GO:0006261 115 0.032
growth GO:0040007 157 0.032
positive regulation of transport GO:0051050 32 0.032
regulation of multi organism process GO:0043900 20 0.031
anatomical structure development GO:0048856 160 0.031
regulation of cell division GO:0051302 113 0.031
regulation of translation GO:0006417 89 0.030
negative regulation of cellular catabolic process GO:0031330 43 0.030
heterocycle catabolic process GO:0046700 494 0.030
protein transport GO:0015031 345 0.030
ion homeostasis GO:0050801 118 0.029
regulation of dna metabolic process GO:0051052 100 0.029
protein localization to organelle GO:0033365 337 0.029
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.029
positive regulation of cellular catabolic process GO:0031331 128 0.029
single organism carbohydrate catabolic process GO:0044724 73 0.029
purine nucleotide metabolic process GO:0006163 376 0.029
regulation of protein serine threonine kinase activity GO:0071900 41 0.028
positive regulation of lipid catabolic process GO:0050996 4 0.028
establishment of protein localization GO:0045184 367 0.028
dephosphorylation GO:0016311 127 0.028
macromolecule catabolic process GO:0009057 383 0.028
negative regulation of cellular component organization GO:0051129 109 0.027
small molecule biosynthetic process GO:0044283 258 0.027
multi organism process GO:0051704 233 0.027
monocarboxylic acid biosynthetic process GO:0072330 35 0.026
positive regulation of phosphate metabolic process GO:0045937 147 0.026
positive regulation of phosphorus metabolic process GO:0010562 147 0.026
cellular ion homeostasis GO:0006873 112 0.026
polysaccharide biosynthetic process GO:0000271 39 0.026
regulation of cellular ketone metabolic process GO:0010565 42 0.026
purine nucleoside triphosphate metabolic process GO:0009144 356 0.025
mitochondrion organization GO:0007005 261 0.025
single organism reproductive process GO:0044702 159 0.025
regulation of cellular component biogenesis GO:0044087 112 0.025
aerobic respiration GO:0009060 55 0.025
ribosome biogenesis GO:0042254 335 0.025
cell cycle checkpoint GO:0000075 82 0.025
organic acid metabolic process GO:0006082 352 0.025
posttranscriptional regulation of gene expression GO:0010608 115 0.025
positive regulation of cellular biosynthetic process GO:0031328 336 0.024
negative regulation of organelle organization GO:0010639 103 0.024
organophosphate biosynthetic process GO:0090407 182 0.024
negative regulation of catabolic process GO:0009895 43 0.024
regulation of conjugation GO:0046999 16 0.024
covalent chromatin modification GO:0016569 119 0.024
ribonucleotide metabolic process GO:0009259 377 0.024
fungal type cell wall organization or biogenesis GO:0071852 169 0.024
regulation of gene expression epigenetic GO:0040029 147 0.024
nucleotide metabolic process GO:0009117 453 0.024
cellular polysaccharide metabolic process GO:0044264 55 0.024
nucleoside triphosphate metabolic process GO:0009141 364 0.023
cellular response to oxidative stress GO:0034599 94 0.023
regulation of conjugation with cellular fusion GO:0031137 16 0.023
ncrna processing GO:0034470 330 0.022
mrna catabolic process GO:0006402 93 0.022
conjugation with cellular fusion GO:0000747 106 0.022
organonitrogen compound biosynthetic process GO:1901566 314 0.022
negative regulation of transcription from rna polymerase ii promoter by pheromones GO:0046020 10 0.022
nuclear division GO:0000280 263 0.022
regulation of transferase activity GO:0051338 83 0.022
signaling GO:0023052 208 0.021
regulation of filamentous growth of a population of unicellular organisms GO:1900428 36 0.021
establishment of protein localization to membrane GO:0090150 99 0.021
sphingolipid biosynthetic process GO:0030148 29 0.021
regulation of reproductive process GO:2000241 24 0.021
organic acid biosynthetic process GO:0016053 152 0.021
negative regulation of gene expression epigenetic GO:0045814 147 0.021
regulation of lipid biosynthetic process GO:0046890 32 0.021
nucleotide biosynthetic process GO:0009165 79 0.021
carbohydrate catabolic process GO:0016052 77 0.020
single organism developmental process GO:0044767 258 0.020
nucleobase containing small molecule metabolic process GO:0055086 491 0.020
regulation of transcription by pheromones GO:0009373 14 0.020
fungal type cell wall organization GO:0031505 145 0.020
positive regulation of cellular component organization GO:0051130 116 0.020
regulation of transport GO:0051049 85 0.020
conjugation GO:0000746 107 0.020
regulation of growth GO:0040008 50 0.020
trna metabolic process GO:0006399 151 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.019
positive regulation of biosynthetic process GO:0009891 336 0.019
anion transport GO:0006820 145 0.019
oxoacid metabolic process GO:0043436 351 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.019
response to oxygen containing compound GO:1901700 61 0.019
cellular response to pheromone GO:0071444 88 0.019
cellular lipid metabolic process GO:0044255 229 0.019
cellular response to organic substance GO:0071310 159 0.019
protein ubiquitination GO:0016567 118 0.018
proteolysis GO:0006508 268 0.018
negative regulation of response to stimulus GO:0048585 40 0.018
cellular response to heat GO:0034605 53 0.018
positive regulation of rna biosynthetic process GO:1902680 286 0.018
regulation of cellular response to drug GO:2001038 3 0.018
reproductive process in single celled organism GO:0022413 145 0.018
regulation of dna dependent dna replication GO:0090329 37 0.018
regulation of mitosis GO:0007088 65 0.018
organic anion transport GO:0015711 114 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.018
regulation of nuclear division GO:0051783 103 0.018
regulation of transmembrane transporter activity GO:0022898 1 0.017
regulation of lipid catabolic process GO:0050994 4 0.017
carboxylic acid transport GO:0046942 74 0.017
establishment of organelle localization GO:0051656 96 0.017
ribonucleoside biosynthetic process GO:0042455 37 0.017
response to nitrosative stress GO:0051409 3 0.017
cellular macromolecule catabolic process GO:0044265 363 0.017
regulation of response to stimulus GO:0048583 157 0.017
signal transduction GO:0007165 208 0.017
dna templated transcription termination GO:0006353 42 0.017
negative regulation of conjugation GO:0031135 5 0.017
histone modification GO:0016570 119 0.017
positive regulation of catabolic process GO:0009896 135 0.017
small molecule catabolic process GO:0044282 88 0.016
positive regulation of programmed cell death GO:0043068 3 0.016
regulation of sodium ion transport GO:0002028 1 0.016
regulation of glucose metabolic process GO:0010906 27 0.016
purine containing compound biosynthetic process GO:0072522 53 0.016
cellular metal ion homeostasis GO:0006875 78 0.016
cellular developmental process GO:0048869 191 0.016
positive regulation of transcription dna templated GO:0045893 286 0.016
negative regulation of cellular hyperosmotic salinity response by negative regulation of transcription from rna polymerase ii promoter GO:1900464 2 0.016
reproduction of a single celled organism GO:0032505 191 0.016
hexose metabolic process GO:0019318 78 0.016
protein localization to membrane GO:0072657 102 0.016
glycogen biosynthetic process GO:0005978 17 0.016
anatomical structure formation involved in morphogenesis GO:0048646 136 0.015
meiotic cell cycle process GO:1903046 229 0.015
positive regulation of cell death GO:0010942 3 0.015
cell wall organization or biogenesis GO:0071554 190 0.015
regulation of transcription from rna polymerase ii promoter by pheromones GO:0046019 14 0.015
regulation of transmembrane transport GO:0034762 14 0.015
glycosyl compound metabolic process GO:1901657 398 0.015
regulation of gtpase activity GO:0043087 84 0.015
dna repair GO:0006281 236 0.015
positive regulation of rna metabolic process GO:0051254 294 0.015
protein targeting to mitochondrion GO:0006626 56 0.015
regulation of transporter activity GO:0032409 1 0.015
chromatin remodeling GO:0006338 80 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.014
purine nucleoside biosynthetic process GO:0042451 31 0.014
regulation of filamentous growth GO:0010570 38 0.014
rrna metabolic process GO:0016072 244 0.014
regulation of vesicle mediated transport GO:0060627 39 0.014
ribonucleoside metabolic process GO:0009119 389 0.014
organic acid catabolic process GO:0016054 71 0.014
protein localization to mitochondrion GO:0070585 63 0.014
protein modification by small protein conjugation GO:0032446 144 0.014
positive regulation of intracellular protein transport GO:0090316 3 0.014
nucleoside metabolic process GO:0009116 394 0.014
proteasomal protein catabolic process GO:0010498 141 0.014
establishment of protein localization to organelle GO:0072594 278 0.014
positive regulation of fatty acid oxidation GO:0046321 3 0.014
organic cyclic compound catabolic process GO:1901361 499 0.014
g1 s transition of mitotic cell cycle GO:0000082 64 0.014
positive regulation of protein modification process GO:0031401 49 0.014
regulation of metal ion transport GO:0010959 2 0.014
positive regulation of sodium ion transport GO:0010765 1 0.014
response to calcium ion GO:0051592 1 0.014
cellular respiration GO:0045333 82 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
negative regulation of dna metabolic process GO:0051053 36 0.013
dna integrity checkpoint GO:0031570 41 0.013
fatty acid biosynthetic process GO:0006633 22 0.013
regulation of purine nucleotide metabolic process GO:1900542 109 0.013
cellular ketone metabolic process GO:0042180 63 0.013
lipid catabolic process GO:0016042 33 0.013
cell budding GO:0007114 48 0.013
negative regulation of sister chromatid segregation GO:0033046 24 0.013
positive regulation of translation GO:0045727 34 0.013
protein modification by small protein conjugation or removal GO:0070647 172 0.013
phospholipid biosynthetic process GO:0008654 89 0.013
organonitrogen compound catabolic process GO:1901565 404 0.013
protein dephosphorylation GO:0006470 40 0.013
vacuole organization GO:0007033 75 0.013
response to organic substance GO:0010033 182 0.013
replicative cell aging GO:0001302 46 0.013
tor signaling GO:0031929 17 0.013
meiotic cell cycle GO:0051321 272 0.012
negative regulation of molecular function GO:0044092 68 0.012
ribonucleoprotein complex subunit organization GO:0071826 152 0.012
regulation of nucleotide metabolic process GO:0006140 110 0.012
sporulation GO:0043934 132 0.012
chromatin organization GO:0006325 242 0.012
protein complex biogenesis GO:0070271 314 0.012
regulation of transcription from rna polymerase i promoter GO:0006356 36 0.012
response to anoxia GO:0034059 3 0.012
rna transport GO:0050658 92 0.012
rna catabolic process GO:0006401 118 0.012
regulation of fatty acid oxidation GO:0046320 3 0.012
developmental process GO:0032502 261 0.012
monovalent inorganic cation transport GO:0015672 78 0.012
nucleobase containing compound catabolic process GO:0034655 479 0.012
external encapsulating structure organization GO:0045229 146 0.012
metal ion transport GO:0030001 75 0.011
protein maturation GO:0051604 76 0.011
rna export from nucleus GO:0006405 88 0.011
dna damage checkpoint GO:0000077 29 0.011
cofactor metabolic process GO:0051186 126 0.011
positive regulation of intracellular transport GO:0032388 4 0.011
nucleobase containing compound transport GO:0015931 124 0.011
sex determination GO:0007530 32 0.011
positive regulation of cellular protein metabolic process GO:0032270 89 0.011
cell cycle g1 s phase transition GO:0044843 64 0.011
single species surface biofilm formation GO:0090606 3 0.011
purine nucleoside metabolic process GO:0042278 380 0.011
positive regulation of molecular function GO:0044093 185 0.011
regulation of generation of precursor metabolites and energy GO:0043467 23 0.011
protein export from nucleus GO:0006611 17 0.011
anatomical structure homeostasis GO:0060249 74 0.011
ribonucleotide biosynthetic process GO:0009260 44 0.011
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.011
organelle localization GO:0051640 128 0.011
nitrogen utilization GO:0019740 21 0.011
sporulation resulting in formation of a cellular spore GO:0030435 129 0.011
positive regulation of transcription from rna polymerase ii promoter in response to acidic ph GO:0061402 4 0.011
membrane lipid biosynthetic process GO:0046467 54 0.011
positive regulation of apoptotic process GO:0043065 3 0.011
acetate biosynthetic process GO:0019413 4 0.011
ergosterol metabolic process GO:0008204 31 0.011
nucleic acid transport GO:0050657 94 0.011
regulation of transcription from rna polymerase ii promoter in response to zinc ion starvation GO:0034225 3 0.011
regulation of response to drug GO:2001023 3 0.011
ascospore formation GO:0030437 107 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.010
sexual sporulation GO:0034293 113 0.010
rrna processing GO:0006364 227 0.010
anatomical structure morphogenesis GO:0009653 160 0.010
microtubule based process GO:0007017 117 0.010

PCL8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027