Saccharomyces cerevisiae

17 known processes

MDL2 (YPL270W)

Mdl2p

MDL2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transport GO:0006811 274 0.526
vacuolar transport GO:0007034 145 0.506
intracellular protein transport GO:0006886 319 0.456
transmembrane transport GO:0055085 349 0.397
Yeast
organonitrogen compound biosynthetic process GO:1901566 314 0.368
establishment of protein localization to organelle GO:0072594 278 0.311
single organism cellular localization GO:1902580 375 0.300
protein targeting GO:0006605 272 0.292
nucleobase containing small molecule metabolic process GO:0055086 491 0.288
Yeast
cellular respiration GO:0045333 82 0.253
purine containing compound metabolic process GO:0072521 400 0.240
Yeast
glycosyl compound metabolic process GO:1901657 398 0.239
Yeast
nucleoside phosphate metabolic process GO:0006753 458 0.234
Yeast
oxidation reduction process GO:0055114 353 0.220
protein transport GO:0015031 345 0.215
glycosyl compound biosynthetic process GO:1901659 42 0.197
cation transport GO:0006812 166 0.193
establishment of protein localization GO:0045184 367 0.187
regulation of biological quality GO:0065008 391 0.183
purine containing compound biosynthetic process GO:0072522 53 0.176
nucleotide metabolic process GO:0009117 453 0.173
Yeast
ribonucleotide metabolic process GO:0009259 377 0.166
Yeast
ribose phosphate metabolic process GO:0019693 384 0.164
Yeast
purine ribonucleoside metabolic process GO:0046128 380 0.164
Yeast
cellular response to chemical stimulus GO:0070887 315 0.163
purine nucleotide biosynthetic process GO:0006164 41 0.159
organophosphate metabolic process GO:0019637 597 0.155
Yeast
positive regulation of biosynthetic process GO:0009891 336 0.152
generation of precursor metabolites and energy GO:0006091 147 0.150
oxoacid metabolic process GO:0043436 351 0.146
carbohydrate derivative metabolic process GO:1901135 549 0.142
Yeast
carbohydrate derivative biosynthetic process GO:1901137 181 0.140
ribonucleoside metabolic process GO:0009119 389 0.139
Yeast
response to chemical GO:0042221 390 0.138
cellular response to extracellular stimulus GO:0031668 150 0.137
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.133
homeostatic process GO:0042592 227 0.129
organic anion transport GO:0015711 114 0.127
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.125
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.121
Yeast
positive regulation of nucleic acid templated transcription GO:1903508 286 0.120
ion transmembrane transport GO:0034220 200 0.119
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.119
cell communication GO:0007154 345 0.118
aerobic respiration GO:0009060 55 0.114
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.113
Yeast
anion transport GO:0006820 145 0.111
nucleoside metabolic process GO:0009116 394 0.111
Yeast
chemical homeostasis GO:0048878 137 0.107
organic acid metabolic process GO:0006082 352 0.105
cellular response to nutrient levels GO:0031669 144 0.104
single organism catabolic process GO:0044712 619 0.102
Yeast
atp metabolic process GO:0046034 251 0.101
Yeast
nucleoside monophosphate metabolic process GO:0009123 267 0.097
Yeast
positive regulation of transcription dna templated GO:0045893 286 0.095
inorganic ion transmembrane transport GO:0098660 109 0.095
purine nucleotide metabolic process GO:0006163 376 0.094
Yeast
mitochondrial transport GO:0006839 76 0.092
Yeast
establishment of protein localization to vacuole GO:0072666 91 0.092
purine nucleoside biosynthetic process GO:0042451 31 0.092
nucleoside biosynthetic process GO:0009163 38 0.091
organic cyclic compound catabolic process GO:1901361 499 0.091
Yeast
protein catabolic process GO:0030163 221 0.091
nucleoside phosphate biosynthetic process GO:1901293 80 0.090
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.089
response to extracellular stimulus GO:0009991 156 0.088
proteolysis GO:0006508 268 0.086
nucleoside triphosphate metabolic process GO:0009141 364 0.085
Yeast
protein modification by small protein conjugation or removal GO:0070647 172 0.085
cellular chemical homeostasis GO:0055082 123 0.082
cation homeostasis GO:0055080 105 0.082
purine ribonucleoside monophosphate biosynthetic process GO:0009168 28 0.080
nucleoside monophosphate biosynthetic process GO:0009124 33 0.079
nucleoside catabolic process GO:0009164 335 0.077
Yeast
purine nucleoside metabolic process GO:0042278 380 0.076
Yeast
cellular homeostasis GO:0019725 138 0.075
organic acid transport GO:0015849 77 0.073
protein localization to organelle GO:0033365 337 0.072
protein targeting to vacuole GO:0006623 91 0.069
cellular amino acid metabolic process GO:0006520 225 0.069
positive regulation of rna metabolic process GO:0051254 294 0.069
positive regulation of macromolecule metabolic process GO:0010604 394 0.067
positive regulation of rna biosynthetic process GO:1902680 286 0.066
regulation of response to stimulus GO:0048583 157 0.065
organelle localization GO:0051640 128 0.065
purine nucleoside triphosphate metabolic process GO:0009144 356 0.065
Yeast
trna metabolic process GO:0006399 151 0.064
regulation of dna replication GO:0006275 51 0.063
purine ribonucleotide metabolic process GO:0009150 372 0.062
Yeast
glycosyl compound catabolic process GO:1901658 335 0.060
Yeast
cellular ion homeostasis GO:0006873 112 0.059
carboxylic acid transport GO:0046942 74 0.058
cellular nitrogen compound catabolic process GO:0044270 494 0.057
Yeast
aromatic compound catabolic process GO:0019439 491 0.057
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.056
nucleotide biosynthetic process GO:0009165 79 0.056
regulation of localization GO:0032879 127 0.055
carboxylic acid metabolic process GO:0019752 338 0.055
positive regulation of gene expression GO:0010628 321 0.054
heterocycle catabolic process GO:0046700 494 0.054
Yeast
nucleobase containing compound catabolic process GO:0034655 479 0.052
Yeast
signal transduction GO:0007165 208 0.052
ribonucleoside monophosphate metabolic process GO:0009161 265 0.051
Yeast
lipid transport GO:0006869 58 0.051
ribonucleoside monophosphate biosynthetic process GO:0009156 31 0.049
carbohydrate transport GO:0008643 33 0.049
positive regulation of cellular biosynthetic process GO:0031328 336 0.048
cellular response to organic substance GO:0071310 159 0.048
response to oxygen containing compound GO:1901700 61 0.045
pyridine containing compound metabolic process GO:0072524 53 0.044
response to external stimulus GO:0009605 158 0.044
protein complex assembly GO:0006461 302 0.044
protein complex biogenesis GO:0070271 314 0.044
macromolecule catabolic process GO:0009057 383 0.044
ribonucleoside catabolic process GO:0042454 332 0.043
Yeast
ion homeostasis GO:0050801 118 0.043
vesicle mediated transport GO:0016192 335 0.043
intracellular signal transduction GO:0035556 112 0.043
signaling GO:0023052 208 0.042
ribonucleotide biosynthetic process GO:0009260 44 0.041
single organism membrane organization GO:0044802 275 0.041
protein modification by small protein conjugation GO:0032446 144 0.040
regulation of cellular catabolic process GO:0031329 195 0.039
regulation of cellular component organization GO:0051128 334 0.039
response to organic substance GO:0010033 182 0.038
cellular macromolecule catabolic process GO:0044265 363 0.037
single organism signaling GO:0044700 208 0.037
membrane organization GO:0061024 276 0.036
regulation of catabolic process GO:0009894 199 0.036
carboxylic acid biosynthetic process GO:0046394 152 0.035
endomembrane system organization GO:0010256 74 0.034
organophosphate catabolic process GO:0046434 338 0.034
Yeast
energy derivation by oxidation of organic compounds GO:0015980 125 0.034
multi organism process GO:0051704 233 0.033
cellular cation homeostasis GO:0030003 100 0.033
modification dependent protein catabolic process GO:0019941 181 0.033
response to starvation GO:0042594 96 0.033
purine nucleoside monophosphate metabolic process GO:0009126 262 0.032
Yeast
meiotic cell cycle process GO:1903046 229 0.032
organophosphate ester transport GO:0015748 45 0.032
negative regulation of gene expression epigenetic GO:0045814 147 0.032
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.032
Yeast
organonitrogen compound catabolic process GO:1901565 404 0.032
Yeast
alpha amino acid biosynthetic process GO:1901607 91 0.032
cellular protein complex assembly GO:0043623 209 0.032
ribose phosphate biosynthetic process GO:0046390 50 0.031
sphingolipid metabolic process GO:0006665 41 0.031
negative regulation of transcription dna templated GO:0045892 258 0.031
response to organic cyclic compound GO:0014070 1 0.031
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.030
ribonucleoside triphosphate metabolic process GO:0009199 356 0.030
Yeast
cation transmembrane transport GO:0098655 135 0.030
carbohydrate derivative catabolic process GO:1901136 339 0.029
Yeast
developmental process GO:0032502 261 0.029
nucleoside phosphate catabolic process GO:1901292 331 0.029
Yeast
dna dependent dna replication GO:0006261 115 0.028
peptidyl amino acid modification GO:0018193 116 0.028
purine ribonucleotide biosynthetic process GO:0009152 39 0.028
purine nucleotide catabolic process GO:0006195 328 0.028
Yeast
cellular amine metabolic process GO:0044106 51 0.028
amine metabolic process GO:0009308 51 0.027
regulation of growth GO:0040008 50 0.027
cellular response to external stimulus GO:0071496 150 0.027
endocytosis GO:0006897 90 0.026
modification dependent macromolecule catabolic process GO:0043632 203 0.026
cellular response to oxygen containing compound GO:1901701 43 0.026
monocarboxylic acid transport GO:0015718 24 0.025
nitrogen compound transport GO:0071705 212 0.025
Yeast
regulation of signal transduction GO:0009966 114 0.024
cellular response to starvation GO:0009267 90 0.024
nucleotide catabolic process GO:0009166 330 0.024
Yeast
lipid localization GO:0010876 60 0.023
conjugation with cellular fusion GO:0000747 106 0.023
organic acid biosynthetic process GO:0016053 152 0.023
purine nucleoside triphosphate catabolic process GO:0009146 329 0.023
Yeast
nucleoside monophosphate catabolic process GO:0009125 224 0.022
Yeast
purine nucleoside monophosphate biosynthetic process GO:0009127 28 0.022
protein ubiquitination GO:0016567 118 0.022
mitochondrial genome maintenance GO:0000002 40 0.022
cellular metal ion homeostasis GO:0006875 78 0.022
hydrogen transport GO:0006818 61 0.022
regulation of cellular component biogenesis GO:0044087 112 0.021
maintenance of location GO:0051235 66 0.021
response to carbohydrate GO:0009743 14 0.021
mrna metabolic process GO:0016071 269 0.021
establishment of organelle localization GO:0051656 96 0.021
anion transmembrane transport GO:0098656 79 0.021
purine containing compound catabolic process GO:0072523 332 0.020
Yeast
organophosphate biosynthetic process GO:0090407 182 0.020
ribonucleoside biosynthetic process GO:0042455 37 0.020
response to nutrient levels GO:0031667 150 0.020
nucleoside triphosphate biosynthetic process GO:0009142 22 0.019
protein localization to membrane GO:0072657 102 0.019
purine nucleoside monophosphate catabolic process GO:0009128 224 0.019
Yeast
response to oxidative stress GO:0006979 99 0.019
iron sulfur cluster assembly GO:0016226 22 0.019
endosomal transport GO:0016197 86 0.019
regulation of cellular protein metabolic process GO:0032268 232 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.019
small gtpase mediated signal transduction GO:0007264 36 0.018
ribonucleoside triphosphate catabolic process GO:0009203 327 0.018
Yeast
purine nucleoside catabolic process GO:0006152 330 0.018
Yeast
lipid metabolic process GO:0006629 269 0.018
atp catabolic process GO:0006200 224 0.018
Yeast
positive regulation of secretion GO:0051047 2 0.018
ubiquitin dependent protein catabolic process GO:0006511 181 0.018
cellular developmental process GO:0048869 191 0.018
conjugation GO:0000746 107 0.018
membrane budding GO:0006900 22 0.018
dna replication GO:0006260 147 0.018
regulation of dna metabolic process GO:0051052 100 0.018
ncrna processing GO:0034470 330 0.018
regulation of cellular ketone metabolic process GO:0010565 42 0.018
purine ribonucleotide catabolic process GO:0009154 327 0.018
Yeast
single organism reproductive process GO:0044702 159 0.017
regulation of cellular localization GO:0060341 50 0.017
negative regulation of cellular metabolic process GO:0031324 407 0.017
response to inorganic substance GO:0010035 47 0.017
cellular protein catabolic process GO:0044257 213 0.017
monosaccharide transport GO:0015749 24 0.017
regulation of cellular amine metabolic process GO:0033238 21 0.017
regulation of cell communication GO:0010646 124 0.016
small molecule biosynthetic process GO:0044283 258 0.016
reproductive process GO:0022414 248 0.016
cellular response to abiotic stimulus GO:0071214 62 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.016
response to hypoxia GO:0001666 4 0.016
coenzyme metabolic process GO:0006732 104 0.016
protein localization to mitochondrion GO:0070585 63 0.016
cellular component movement GO:0006928 20 0.016
response to monosaccharide GO:0034284 13 0.016
regulation of transport GO:0051049 85 0.016
organic hydroxy compound transport GO:0015850 41 0.016
cellular lipid metabolic process GO:0044255 229 0.016
cytoskeleton organization GO:0007010 230 0.016
metallo sulfur cluster assembly GO:0031163 22 0.016
regulation of organelle organization GO:0033043 243 0.016
cellular amide metabolic process GO:0043603 59 0.016
cellular response to endogenous stimulus GO:0071495 22 0.016
single organism developmental process GO:0044767 258 0.015
response to nutrient GO:0007584 52 0.015
cellular component disassembly GO:0022411 86 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.015
Yeast
ribonucleoside monophosphate catabolic process GO:0009158 224 0.015
Yeast
positive regulation of cell death GO:0010942 3 0.015
positive regulation of cellular component organization GO:0051130 116 0.015
positive regulation of cellular catabolic process GO:0031331 128 0.015
organelle fusion GO:0048284 85 0.015
ribonucleoprotein complex subunit organization GO:0071826 152 0.014
pyridine nucleotide metabolic process GO:0019362 45 0.014
growth GO:0040007 157 0.014
positive regulation of programmed cell death GO:0043068 3 0.014
sexual reproduction GO:0019953 216 0.014
positive regulation of catalytic activity GO:0043085 178 0.014
actin filament based process GO:0030029 104 0.014
late endosome to vacuole transport GO:0045324 42 0.014
ascospore formation GO:0030437 107 0.014
dicarboxylic acid metabolic process GO:0043648 20 0.014
amino acid activation GO:0043038 35 0.014
protein targeting to mitochondrion GO:0006626 56 0.014
reproduction of a single celled organism GO:0032505 191 0.014
hydrogen ion transmembrane transport GO:1902600 49 0.014
phosphatidylcholine metabolic process GO:0046470 20 0.013
fatty acid metabolic process GO:0006631 51 0.013
chromatin silencing GO:0006342 147 0.013
nucleobase containing compound transport GO:0015931 124 0.013
dna recombination GO:0006310 172 0.013
positive regulation of intracellular transport GO:0032388 4 0.013
inorganic cation transmembrane transport GO:0098662 98 0.013
regulation of signaling GO:0023051 119 0.013
posttranscriptional regulation of gene expression GO:0010608 115 0.013
ras protein signal transduction GO:0007265 29 0.013
amino acid transport GO:0006865 45 0.013
glucose metabolic process GO:0006006 65 0.013
positive regulation of cytoplasmic transport GO:1903651 4 0.013
response to hexose GO:0009746 13 0.013
late endosome to vacuole transport via multivesicular body sorting pathway GO:0032511 26 0.013
er associated ubiquitin dependent protein catabolic process GO:0030433 46 0.013
multi organism reproductive process GO:0044703 216 0.013
negative regulation of macromolecule metabolic process GO:0010605 375 0.013
cellular ketone metabolic process GO:0042180 63 0.013
ribonucleotide catabolic process GO:0009261 327 0.013
Yeast
cellular response to nitrogen compound GO:1901699 14 0.013
establishment or maintenance of cell polarity GO:0007163 96 0.013
phospholipid metabolic process GO:0006644 125 0.013
purine ribonucleoside catabolic process GO:0046130 330 0.013
Yeast
negative regulation of nucleic acid templated transcription GO:1903507 260 0.012
mitochondrion localization GO:0051646 29 0.012
purine ribonucleoside triphosphate biosynthetic process GO:0009206 17 0.012
macromolecular complex disassembly GO:0032984 80 0.012
lipid modification GO:0030258 37 0.012
positive regulation of intracellular protein transport GO:0090316 3 0.012
regulation of anatomical structure size GO:0090066 50 0.012
negative regulation of cellular component organization GO:0051129 109 0.012
anatomical structure development GO:0048856 160 0.012
nucleoside triphosphate catabolic process GO:0009143 329 0.012
Yeast
vacuole organization GO:0007033 75 0.012
cellular response to hypoxia GO:0071456 4 0.012
cellular polysaccharide metabolic process GO:0044264 55 0.012
cellular amino acid biosynthetic process GO:0008652 118 0.011
positive regulation of catabolic process GO:0009896 135 0.011
reproductive process in single celled organism GO:0022413 145 0.011
positive regulation of apoptotic process GO:0043065 3 0.011
regulation of protein complex assembly GO:0043254 77 0.011
reciprocal meiotic recombination GO:0007131 54 0.011
regulation of protein metabolic process GO:0051246 237 0.011
regulation of cellular amino acid metabolic process GO:0006521 16 0.011
monocarboxylic acid metabolic process GO:0032787 122 0.011
regulation of lipid metabolic process GO:0019216 45 0.011
negative regulation of rna biosynthetic process GO:1902679 260 0.011
lipid catabolic process GO:0016042 33 0.011
regulation of translation GO:0006417 89 0.011
alpha amino acid metabolic process GO:1901605 124 0.010
nucleosome organization GO:0034728 63 0.010
nicotinamide nucleotide metabolic process GO:0046496 44 0.010
single organism carbohydrate metabolic process GO:0044723 237 0.010
meiotic cell cycle GO:0051321 272 0.010
regulation of cellular component size GO:0032535 50 0.010
membrane lipid metabolic process GO:0006643 67 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.010
cell differentiation GO:0030154 161 0.010
nuclear transcribed mrna catabolic process GO:0000956 89 0.010
localization within membrane GO:0051668 29 0.010

MDL2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
disease of metabolism DOID:0014667 0 0.023
inherited metabolic disorder DOID:655 0 0.023