Danio rerio

109 known processes

dctn2

dynactin 2 (p50)

(Aliases: dynamitin,zgc:63867,MGC63867)

dctn2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.346
fertilization GO:0009566 3 0.220
Worm
pronuclear migration GO:0035046 1 0.195
Worm
response to stress GO:0006950 263 0.154
regulation of metabolic process GO:0019222 359 0.138
neuron differentiation GO:0030182 353 0.134
single fertilization GO:0007338 3 0.131
Worm
regionalization GO:0003002 274 0.116
response to topologically incorrect protein GO:0035966 2 0.105
aging GO:0007568 2 0.100
phagocytosis GO:0006909 3 0.085
negative regulation of biological process GO:0048519 304 0.085
eye development GO:0001654 277 0.084
cellular component morphogenesis GO:0032989 336 0.079
embryonic organ development GO:0048568 381 0.076
gene expression GO:0010467 252 0.076
organic substance biosynthetic process GO:1901576 289 0.076
macromolecular complex subunit organization GO:0043933 74 0.074
organelle organization GO:0006996 227 0.073
heterocycle metabolic process GO:0046483 290 0.072
protein metabolic process GO:0019538 183 0.072
cellular aromatic compound metabolic process GO:0006725 295 0.069
positive regulation of transport GO:0051050 2 0.069
nucleoside monophosphate catabolic process GO:0009125 4 0.067
camera type eye development GO:0043010 222 0.065
regulation of multicellular organismal process GO:0051239 277 0.064
regulation of cellular metabolic process GO:0031323 320 0.063
nitrogen compound metabolic process GO:0006807 319 0.063
embryo development ending in birth or egg hatching GO:0009792 271 0.063
Worm
nuclear migration GO:0007097 3 0.061
Worm
cellular nitrogen compound metabolic process GO:0034641 290 0.056
positive regulation of cellular process GO:0048522 201 0.055
sensory organ morphogenesis GO:0090596 200 0.054
morphogenesis of an epithelium GO:0002009 333 0.054
cellular macromolecule metabolic process GO:0044260 391 0.054
nucleobase containing compound metabolic process GO:0006139 274 0.053
regulation of gene expression GO:0010468 265 0.053
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.053
protein complex biogenesis GO:0070271 30 0.052
regulation of primary metabolic process GO:0080090 311 0.051
reproductive process GO:0022414 40 0.051
ribonucleoside monophosphate catabolic process GO:0009158 4 0.051
single organism localization GO:1902578 225 0.049
Worm
response to chemical GO:0042221 320 0.049
protein secretion GO:0009306 1 0.047
transport GO:0006810 220 0.047
regulation of establishment of protein localization GO:0070201 4 0.047
atp catabolic process GO:0006200 4 0.046
tube morphogenesis GO:0035239 349 0.046
regulation of biological quality GO:0065008 263 0.045
maintenance of location GO:0051235 4 0.043
eye morphogenesis GO:0048592 144 0.042
positive regulation of biological process GO:0048518 253 0.041
system process GO:0003008 185 0.041
blood vessel development GO:0001568 246 0.040
retina development in camera type eye GO:0060041 146 0.039
cellular protein metabolic process GO:0044267 129 0.039
locomotion GO:0040011 313 0.038
generation of neurons GO:0048699 385 0.037
positive regulation of catabolic process GO:0009896 4 0.037
cell cycle process GO:0022402 53 0.036
Worm
regulation of protein catabolic process GO:0042176 1 0.036
negative regulation of catabolic process GO:0009895 3 0.036
regulation of macromolecule metabolic process GO:0060255 317 0.035
cellular component biogenesis GO:0044085 178 0.035
heart development GO:0007507 313 0.035
lipid storage GO:0019915 1 0.035
dorsal ventral pattern formation GO:0009953 125 0.034
modification dependent macromolecule catabolic process GO:0043632 3 0.034
regulation of signal transduction GO:0009966 225 0.034
localization of cell GO:0051674 244 0.033
positive regulation of cell cycle GO:0045787 3 0.033
regulation of developmental process GO:0050793 247 0.033
cell projection organization GO:0030030 284 0.033
cellular component movement GO:0006928 335 0.033
positive regulation of secretion GO:0051047 1 0.033
vasculature development GO:0001944 278 0.033
cellular macromolecule biosynthetic process GO:0034645 224 0.032
multicellular organism growth GO:0035264 4 0.032
pronephros development GO:0048793 69 0.032
cell morphogenesis GO:0000902 289 0.032
cilium organization GO:0044782 71 0.032
establishment of protein localization to organelle GO:0072594 4 0.031
skin development GO:0043588 54 0.031
cellular protein catabolic process GO:0044257 4 0.031
negative regulation of cellular process GO:0048523 283 0.030
macromolecule biosynthetic process GO:0009059 227 0.030
positive regulation of secretion by cell GO:1903532 1 0.030
regulation of macromolecule biosynthetic process GO:0010556 225 0.029
purine nucleoside monophosphate catabolic process GO:0009128 4 0.029
single organism reproductive process GO:0044702 40 0.029
regulation of signaling GO:0023051 235 0.029
retina morphogenesis in camera type eye GO:0060042 79 0.029
cellular response to topologically incorrect protein GO:0035967 2 0.029
exocytosis GO:0006887 1 0.028
nonmotile primary cilium assembly GO:0035058 2 0.028
single organism membrane fusion GO:0044801 2 0.028
cellular component assembly GO:0022607 170 0.028
sensory organ development GO:0007423 393 0.028
response to drug GO:0042493 3 0.028
cytokinesis GO:0000910 3 0.028
epithelial tube morphogenesis GO:0060562 148 0.028
cell part morphogenesis GO:0032990 246 0.027
mitotic cell cycle GO:0000278 64 0.027
Worm
regulation of cell communication GO:0010646 232 0.027
response to abiotic stimulus GO:0009628 122 0.027
positive regulation of cellular component biogenesis GO:0044089 3 0.026
single organism transport GO:0044765 206 0.026
renal system development GO:0072001 94 0.026
single organism organelle organization GO:1902589 199 0.026
meiotic cell cycle process GO:1903046 3 0.026
axis specification GO:0009798 43 0.026
blood vessel morphogenesis GO:0048514 216 0.026
organic cyclic compound metabolic process GO:1901360 301 0.026
cell projection morphogenesis GO:0048858 244 0.025
neurotransmitter transport GO:0006836 2 0.025
kidney development GO:0001822 92 0.025
centrosome organization GO:0051297 1 0.025
phagocytosis engulfment GO:0006911 1 0.025
heterocycle biosynthetic process GO:0018130 215 0.025
stem cell development GO:0048864 82 0.025
nucleic acid metabolic process GO:0090304 244 0.025
inner ear development GO:0048839 126 0.025
primary neural tube formation GO:0014020 1 0.025
guanosine containing compound metabolic process GO:1901068 4 0.025
organelle localization GO:0051640 49 0.024
lamellipodium organization GO:0097581 1 0.024
response to organic substance GO:0010033 153 0.024
gtp metabolic process GO:0046039 4 0.024
regulation of autophagy GO:0010506 3 0.024
regulation of protein complex assembly GO:0043254 3 0.023
guanosine containing compound catabolic process GO:1901069 2 0.023
cellular component disassembly GO:0022411 1 0.023
regulation of response to stimulus GO:0048583 269 0.023
female sex differentiation GO:0046660 4 0.023
brain development GO:0007420 293 0.023
autophagy GO:0006914 4 0.023
lipid homeostasis GO:0055088 3 0.022
lamellipodium assembly GO:0030032 1 0.022
nucleobase containing small molecule metabolic process GO:0055086 32 0.022
modification dependent protein catabolic process GO:0019941 3 0.022
urogenital system development GO:0001655 97 0.022
immune system process GO:0002376 241 0.022
embryonic heart tube development GO:0035050 133 0.022
signal transduction GO:0007165 455 0.022
regulation of meiotic cell cycle GO:0051445 1 0.022
membrane fusion GO:0061025 2 0.021
camera type eye morphogenesis GO:0048593 108 0.021
cell motility GO:0048870 244 0.021
female gonad development GO:0008585 4 0.021
macromolecular complex disassembly GO:0032984 1 0.021
cell substrate adhesion GO:0031589 4 0.021
death GO:0016265 121 0.021
programmed cell death GO:0012501 119 0.021
amine metabolic process GO:0009308 2 0.021
regulation of protein targeting GO:1903533 2 0.021
specification of symmetry GO:0009799 204 0.020
multicellular organismal signaling GO:0035637 22 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
cellular response to external stimulus GO:0071496 2 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
protein acetylation GO:0006473 2 0.020
gtp catabolic process GO:0006184 2 0.020
nuclear import GO:0051170 3 0.020
embryonic organ morphogenesis GO:0048562 274 0.020
meiotic nuclear division GO:0007126 4 0.020
stem cell maintenance GO:0019827 4 0.020
pole plasm assembly GO:0007315 4 0.020
ubiquitin dependent protein catabolic process GO:0006511 3 0.020
regulation of epithelial cell proliferation GO:0050678 3 0.019
tube closure GO:0060606 1 0.019
regulation of reproductive process GO:2000241 4 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
protein complex disassembly GO:0043241 1 0.019
small molecule metabolic process GO:0044281 77 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
head development GO:0060322 303 0.019
organic cyclic compound biosynthetic process GO:1901362 223 0.019
cellular localization GO:0051641 97 0.019
pigmentation GO:0043473 85 0.019
stem cell proliferation GO:0072089 4 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
organelle fusion GO:0048284 3 0.018
gland development GO:0048732 143 0.018
establishment of organelle localization GO:0051656 45 0.018
regulation of mrna processing GO:0050684 3 0.018
regulation of cell substrate adhesion GO:0010810 1 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
establishment of synaptic vesicle localization GO:0097480 1 0.018
regulation of dendrite morphogenesis GO:0048814 3 0.018
developmental programmed cell death GO:0010623 4 0.018
proteasomal protein catabolic process GO:0010498 2 0.018
microtubule organizing center organization GO:0031023 1 0.018
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
cell cycle GO:0007049 93 0.018
Worm
cytoskeleton organization GO:0007010 96 0.018
Worm
digestive system development GO:0055123 289 0.018
transcription dna templated GO:0006351 181 0.018
neuron fate determination GO:0048664 2 0.017
regulation of gtp catabolic process GO:0033124 2 0.017
regulation of protein transport GO:0051223 3 0.017
endosomal transport GO:0016197 2 0.017
translational initiation GO:0006413 3 0.017
growth GO:0040007 174 0.017
negative regulation of synapse assembly GO:0051964 2 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
chordate embryonic development GO:0043009 271 0.017
epithelial cell morphogenesis GO:0003382 2 0.017
cellular biosynthetic process GO:0044249 286 0.017
intracellular signal transduction GO:0035556 85 0.017
negative regulation of metabolic process GO:0009892 86 0.017
cellular amine metabolic process GO:0044106 2 0.017
regulation of multicellular organism growth GO:0040014 4 0.017
establishment of localization GO:0051234 244 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.017
regulation of metal ion transport GO:0010959 4 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
cellular response to unfolded protein GO:0034620 2 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
regulation of cell projection assembly GO:0060491 4 0.016
cellular response to extracellular stimulus GO:0031668 2 0.016
determination of left right symmetry GO:0007368 179 0.016
anterior posterior pattern specification GO:0009952 152 0.016
negative regulation of cellular catabolic process GO:0031330 3 0.016
meiotic chromosome segregation GO:0045132 3 0.016
homeostatic process GO:0042592 142 0.016
spindle assembly GO:0051225 2 0.016
protein complex assembly GO:0006461 30 0.016
apoptotic process GO:0006915 116 0.016
cilium assembly GO:0042384 58 0.016
protein localization to plasma membrane GO:0072659 1 0.016
synaptic vesicle localization GO:0097479 1 0.016
phosphate containing compound metabolic process GO:0006796 108 0.016
digestive tract morphogenesis GO:0048546 231 0.016
transmission of nerve impulse GO:0019226 19 0.016
central nervous system development GO:0007417 387 0.016
protein polymerization GO:0051258 4 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
compound eye development GO:0048749 2 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
positive regulation of apoptotic signaling pathway GO:2001235 1 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
synaptic growth at neuromuscular junction GO:0051124 2 0.015
negative regulation of reproductive process GO:2000242 3 0.015
apoptotic process involved in development GO:1902742 2 0.015
single organism nuclear import GO:1902593 3 0.015
action potential GO:0001508 19 0.015
developmental process involved in reproduction GO:0003006 27 0.015
stem cell division GO:0017145 1 0.015
regulation of oocyte development GO:0060281 3 0.015
cell death GO:0008219 121 0.015
convergent extension GO:0060026 118 0.015
polyol metabolic process GO:0019751 1 0.015
spinal cord development GO:0021510 46 0.015
stem cell differentiation GO:0048863 117 0.015
regulation of apoptotic process GO:0042981 98 0.015
epithelial cell differentiation GO:0030855 116 0.015
golgi vesicle transport GO:0048193 3 0.015
digestive tract development GO:0048565 265 0.015
cell differentiation in spinal cord GO:0021515 40 0.015
regulation of cell development GO:0060284 100 0.015
regulation of neurogenesis GO:0050767 87 0.015
positive regulation of cell adhesion GO:0045785 1 0.015
mitochondrion organization GO:0007005 4 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
negative regulation of protein transport GO:0051224 3 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
positive regulation of notch signaling pathway GO:0045747 3 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
nucleotide metabolic process GO:0009117 28 0.015
regulation of cellular protein catabolic process GO:1903362 1 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.015
spindle assembly involved in mitosis GO:0090307 1 0.014
neuron development GO:0048666 262 0.014
positive regulation of epithelial cell migration GO:0010634 2 0.014
cell projection assembly GO:0030031 64 0.014
cranial nerve development GO:0021545 42 0.014
single organism metabolic process GO:0044710 217 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
nucleic acid templated transcription GO:0097659 181 0.014
protein complex subunit organization GO:0071822 46 0.014
neural retina development GO:0003407 49 0.014
positive regulation of cell division GO:0051781 2 0.014
neurological system process GO:0050877 62 0.014
secondary metabolic process GO:0019748 3 0.014
angiogenesis GO:0001525 158 0.014
central nervous system neuron differentiation GO:0021953 74 0.014
regulation of rna metabolic process GO:0051252 224 0.014
regulation of gtpase activity GO:0043087 2 0.014
somitogenesis GO:0001756 87 0.014
embryonic heart tube morphogenesis GO:0003143 108 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
spermatid development GO:0007286 2 0.014
biosynthetic process GO:0009058 294 0.014
regulation of organ growth GO:0046620 3 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
synaptic vesicle transport GO:0048489 1 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
establishment of protein localization to plasma membrane GO:0090002 1 0.014
reactive oxygen species metabolic process GO:0072593 6 0.014
tissue remodeling GO:0048771 4 0.013
glial cell migration GO:0008347 3 0.013
regulation of response to extracellular stimulus GO:0032104 1 0.013
determination of bilateral symmetry GO:0009855 204 0.013
adherens junction organization GO:0034332 4 0.013
cellular nitrogen compound biosynthetic process GO:0044271 218 0.013
cellular pigmentation GO:0033059 30 0.013
immune system development GO:0002520 191 0.013
macroautophagy GO:0016236 1 0.013
positive regulation of cell substrate adhesion GO:0010811 1 0.013
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.013
synaptic vesicle recycling GO:0036465 1 0.013
regulation of chromosome segregation GO:0051983 1 0.013
apoptotic process involved in morphogenesis GO:0060561 2 0.013
regulation of cell differentiation GO:0045595 142 0.013
membrane invagination GO:0010324 1 0.013
protein depolymerization GO:0051261 1 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
protein import GO:0017038 3 0.013
appendage development GO:0048736 80 0.013
cell division GO:0051301 20 0.013
regulation of mrna splicing via spliceosome GO:0048024 3 0.013
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
regulation of transcription dna templated GO:0006355 213 0.013
cellular response to starvation GO:0009267 1 0.013
mesenchymal cell development GO:0014031 78 0.013
germ line stem cell maintenance GO:0030718 2 0.012
developmental growth GO:0048589 166 0.012
regulation of rna biosynthetic process GO:2001141 213 0.012
rna metabolic process GO:0016070 219 0.012
olfactory bulb development GO:0021772 4 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
nephron morphogenesis GO:0072028 2 0.012
adult behavior GO:0030534 2 0.012
protein stabilization GO:0050821 2 0.012
regulation of organelle assembly GO:1902115 4 0.012
nucleocytoplasmic transport GO:0006913 4 0.012
hatching GO:0035188 4 0.012
protein localization to nucleus GO:0034504 3 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
connective tissue development GO:0061448 99 0.012
regulation of cell death GO:0010941 103 0.012
mechanoreceptor differentiation GO:0042490 37 0.012
regulation of cell shape GO:0008360 1 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
chromosome segregation GO:0007059 12 0.012
Worm
positive regulation of protein complex assembly GO:0031334 2 0.012
heart looping GO:0001947 94 0.012
olfactory lobe development GO:0021988 4 0.012
regulation of muscle contraction GO:0006937 3 0.012
negative regulation of intracellular protein transport GO:0090317 3 0.012
regulation of biosynthetic process GO:0009889 250 0.012
spermatid differentiation GO:0048515 2 0.012
mitotic nuclear division GO:0007067 18 0.012
Worm
segmentation GO:0035282 97 0.012
toxin transport GO:1901998 2 0.012
microtubule based process GO:0007017 60 0.012
Worm
anatomical structure homeostasis GO:0060249 36 0.012
nephron epithelium morphogenesis GO:0072088 1 0.012
mitotic dna integrity checkpoint GO:0044774 4 0.012
protein acylation GO:0043543 3 0.011
cellular protein complex disassembly GO:0043624 1 0.011
response to unfolded protein GO:0006986 2 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
rna localization GO:0006403 4 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
nuclear transport GO:0051169 4 0.011
regulation of wnt signaling pathway GO:0030111 53 0.011
lateral inhibition GO:0046331 1 0.011
cellular response to nutrient levels GO:0031669 2 0.011
alcohol biosynthetic process GO:0046165 2 0.011
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.011
multicellular organism reproduction GO:0032504 35 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
heart jogging GO:0003146 40 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
neuroblast proliferation GO:0007405 2 0.011
regulation of circadian rhythm GO:0042752 4 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
wnt signaling pathway GO:0016055 80 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
regulation of cell activation GO:0050865 1 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
microtubule based movement GO:0007018 33 0.011
developmental maturation GO:0021700 34 0.011
synaptic vesicle endocytosis GO:0048488 1 0.011
negative regulation of stem cell differentiation GO:2000737 2 0.011
epidermis development GO:0008544 48 0.011
mitotic cell cycle process GO:1903047 48 0.011
Worm
insulin like growth factor receptor signaling pathway GO:0048009 4 0.010
detection of abiotic stimulus GO:0009582 24 0.010
cortical cytoskeleton organization GO:0030865 1 0.010
post golgi vesicle mediated transport GO:0006892 1 0.010
negative regulation of secretion GO:0051048 2 0.010
hepaticobiliary system development GO:0061008 98 0.010
cell cycle g1 s phase transition GO:0044843 1 0.010
aromatic compound biosynthetic process GO:0019438 217 0.010
regulation of neurotransmitter secretion GO:0046928 1 0.010
regulation of binding GO:0051098 3 0.010
striated muscle cell differentiation GO:0051146 129 0.010
neuron projection development GO:0031175 180 0.010
determination of heart left right asymmetry GO:0061371 117 0.010
er nucleus signaling pathway GO:0006984 2 0.010
regulation of synaptic plasticity GO:0048167 1 0.010
type b pancreatic cell development GO:0003323 4 0.010
renal tubule morphogenesis GO:0061333 1 0.010
cellular response to light stimulus GO:0071482 4 0.010
pectoral fin development GO:0033339 50 0.010
multicellular organismal response to stress GO:0033555 2 0.010
regulation of wound healing GO:0061041 2 0.010
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.010
small molecule catabolic process GO:0044282 3 0.010
multi organism reproductive process GO:0044703 36 0.010
regulation of dendrite development GO:0050773 3 0.010
kupffer s vesicle development GO:0070121 50 0.010
protein targeting to nucleus GO:0044744 3 0.010
protein import into nucleus GO:0006606 3 0.010

dctn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.016
disease of anatomical entity DOID:7 0 0.016
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011
nervous system disease DOID:863 0 0.011