Danio rerio

60 known processes

dnd

dead end

(Aliases: cb736,fi22d10,wu:fi22d10,zgc:111864)

dnd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pole plasm assembly GO:0007315 4 0.539
regulation of primary metabolic process GO:0080090 311 0.414
regulation of cellular metabolic process GO:0031323 320 0.377
negative regulation of dna recombination GO:0045910 2 0.364
rna localization GO:0006403 4 0.292
response to chemical GO:0042221 320 0.291
Zebrafish
oocyte development GO:0048599 14 0.282
organic substance biosynthetic process GO:1901576 289 0.249
oocyte maturation GO:0001556 4 0.240
immune system process GO:0002376 241 0.219
oocyte anterior posterior axis specification GO:0007314 4 0.218
regulation of metabolic process GO:0019222 359 0.196
macromolecule biosynthetic process GO:0009059 227 0.190
larval development GO:0002164 2 0.189
sexual reproduction GO:0019953 36 0.186
meiosis ii GO:0007135 1 0.155
regulation of response to stimulus GO:0048583 269 0.144
single organism transport GO:0044765 206 0.141
regulation of protein complex assembly GO:0043254 3 0.131
mitotic sister chromatid segregation GO:0000070 6 0.130
response to stress GO:0006950 263 0.124
biosynthetic process GO:0009058 294 0.124
regulation of biosynthetic process GO:0009889 250 0.124
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.122
gene expression GO:0010467 252 0.118
organic cyclic compound metabolic process GO:1901360 301 0.110
embryo development ending in birth or egg hatching GO:0009792 271 0.109
cellular macromolecule metabolic process GO:0044260 391 0.105
regulation of nitrogen compound metabolic process GO:0051171 251 0.103
skin development GO:0043588 54 0.097
cellular nitrogen compound metabolic process GO:0034641 290 0.095
regulation of cellular biosynthetic process GO:0031326 245 0.094
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.093
tube morphogenesis GO:0035239 349 0.087
positive regulation of catabolic process GO:0009896 4 0.084
cellular biosynthetic process GO:0044249 286 0.082
female meiosis ii GO:0007147 1 0.082
phagocytosis GO:0006909 3 0.082
regulation of mrna processing GO:0050684 3 0.081
regulation of signaling GO:0023051 235 0.079
negative regulation of cell communication GO:0010648 96 0.078
cell surface receptor signaling pathway GO:0007166 325 0.077
regionalization GO:0003002 274 0.073
cellular aromatic compound metabolic process GO:0006725 295 0.072
regulation of transcription dna templated GO:0006355 213 0.067
nitrogen compound metabolic process GO:0006807 319 0.065
regulation of signal transduction GO:0009966 225 0.064
regulation of developmental process GO:0050793 247 0.064
negative regulation of protein complex assembly GO:0031333 1 0.064
3 utr mediated mrna stabilization GO:0070935 3 0.063
locomotion GO:0040011 313 0.062
cellular macromolecule biosynthetic process GO:0034645 224 0.061
rhombomere 6 development GO:0021572 4 0.061
regulation of gene expression GO:0010468 265 0.060
regulation of macromolecule metabolic process GO:0060255 317 0.059
regulation of rna metabolic process GO:0051252 224 0.058
regulation of angiogenesis GO:0045765 26 0.056
establishment of localization GO:0051234 244 0.056
segmentation GO:0035282 97 0.056
smad protein complex assembly GO:0007183 1 0.055
positive regulation of cellular catabolic process GO:0031331 3 0.055
negative regulation of cellular process GO:0048523 283 0.055
embryonic axis specification GO:0000578 12 0.054
regulation of cell communication GO:0010646 232 0.054
regulation of macromolecule biosynthetic process GO:0010556 225 0.054
neuron differentiation GO:0030182 353 0.053
Zebrafish
positive regulation of response to stimulus GO:0048584 80 0.051
vasculature development GO:0001944 278 0.050
negative regulation of biological process GO:0048519 304 0.049
cellular component movement GO:0006928 335 0.049
maternal determination of anterior posterior axis embryo GO:0008358 4 0.049
anterior posterior pattern specification GO:0009952 152 0.047
transport GO:0006810 220 0.047
heterocycle metabolic process GO:0046483 290 0.046
oocyte construction GO:0007308 5 0.046
negative regulation of ras protein signal transduction GO:0046580 1 0.045
oocyte differentiation GO:0009994 14 0.045
somite development GO:0061053 96 0.045
positive regulation of translation GO:0045727 1 0.044
nucleic acid templated transcription GO:0097659 181 0.043
regulation of posttranscriptional gene silencing GO:0060147 1 0.043
nucleic acid metabolic process GO:0090304 244 0.042
establishment of blood brain barrier GO:0060856 2 0.042
organic cyclic compound biosynthetic process GO:1901362 223 0.041
regulation of multicellular organismal development GO:2000026 223 0.041
blood vessel development GO:0001568 246 0.041
regulation of reproductive process GO:2000241 4 0.040
single organism organelle organization GO:1902589 199 0.040
transcription dna templated GO:0006351 181 0.039
cell motility GO:0048870 244 0.039
male meiosis GO:0007140 2 0.039
regulation of cell activation GO:0050865 1 0.039
embryonic pattern specification GO:0009880 44 0.038
regulation of biological quality GO:0065008 263 0.038
somitogenesis GO:0001756 87 0.038
aromatic compound biosynthetic process GO:0019438 217 0.038
digestive system development GO:0055123 289 0.038
gastrulation GO:0007369 208 0.037
multi organism process GO:0051704 134 0.036
meiotic chromosome segregation GO:0045132 3 0.035
positive regulation of cell cycle GO:0045787 3 0.034
positive regulation of cellular process GO:0048522 201 0.034
mesoderm development GO:0007498 88 0.034
estrogen metabolic process GO:0008210 2 0.033
negative regulation of gene expression GO:0010629 65 0.033
camera type eye morphogenesis GO:0048593 108 0.033
cell death GO:0008219 121 0.032
ceramide biosynthetic process GO:0046513 1 0.032
regulation of mrna catabolic process GO:0061013 3 0.031
regulation of nucleic acid templated transcription GO:1903506 213 0.031
apoptotic process GO:0006915 116 0.031
positive regulation of purine nucleotide biosynthetic process GO:1900373 8 0.031
developmental maturation GO:0021700 34 0.031
cellular component biogenesis GO:0044085 178 0.030
spermatid development GO:0007286 2 0.030
mitotic cell cycle GO:0000278 64 0.029
cellular component assembly GO:0022607 170 0.029
muscle organ development GO:0007517 101 0.029
regulation of intracellular protein transport GO:0033157 3 0.028
proteasomal protein catabolic process GO:0010498 2 0.028
germ cell development GO:0007281 22 0.028
spindle assembly involved in meiosis GO:0090306 1 0.028
regulation of cellular protein metabolic process GO:0032268 52 0.028
growth GO:0040007 174 0.027
Zebrafish
generation of neurons GO:0048699 385 0.027
Zebrafish
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.027
regulation of cytokine production GO:0001817 3 0.027
stem cell maintenance GO:0019827 4 0.027
regulation of response to stress GO:0080134 36 0.027
autophagy GO:0006914 4 0.026
oogenesis GO:0048477 14 0.026
positive regulation of cellular metabolic process GO:0031325 94 0.026
macromolecular complex subunit organization GO:0043933 74 0.026
regulation of dna recombination GO:0000018 2 0.026
cellular lipid metabolic process GO:0044255 36 0.025
meiotic nuclear division GO:0007126 4 0.025
organelle fission GO:0048285 23 0.025
axis specification GO:0009798 43 0.025
heterocycle biosynthetic process GO:0018130 215 0.025
developmental process involved in reproduction GO:0003006 27 0.024
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.024
spermatid differentiation GO:0048515 2 0.024
regulation of gene silencing by rna GO:0060966 1 0.024
organelle organization GO:0006996 227 0.024
response to external stimulus GO:0009605 264 0.024
Zebrafish
negative regulation of dna metabolic process GO:0051053 4 0.024
cellular macromolecule localization GO:0070727 21 0.024
embryonic heart tube development GO:0035050 133 0.024
negative regulation of response to stimulus GO:0048585 104 0.024
lipid storage GO:0019915 1 0.024
cell projection morphogenesis GO:0048858 244 0.024
Zebrafish
epithelial cell differentiation GO:0030855 116 0.023
positive regulation of developmental process GO:0051094 50 0.023
regulation of autophagy GO:0010506 3 0.022
negative regulation of metabolic process GO:0009892 86 0.022
cell proliferation involved in heart morphogenesis GO:0061323 2 0.022
spemann organizer formation at the embryonic shield GO:0060063 2 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.021
catabolic process GO:0009056 32 0.021
anatomical structure homeostasis GO:0060249 36 0.021
regulation of protein transport GO:0051223 3 0.021
meiotic cell cycle process GO:1903046 3 0.021
regulation of cell maturation GO:1903429 1 0.021
multicellular organism reproduction GO:0032504 35 0.020
signal transduction GO:0007165 455 0.020
female meiotic division GO:0007143 2 0.020
translational initiation GO:0006413 3 0.020
positive regulation of defense response GO:0031349 9 0.020
bmp signaling pathway GO:0030509 52 0.020
cell growth GO:0016049 57 0.020
Zebrafish
ameboidal type cell migration GO:0001667 143 0.019
stem cell division GO:0017145 1 0.019
ganglioside metabolic process GO:0001573 3 0.019
maintenance of location GO:0051235 4 0.019
cell proliferation GO:0008283 80 0.019
epidermis development GO:0008544 48 0.019
regulation of localization GO:0032879 104 0.019
regulation of gtp catabolic process GO:0033124 2 0.019
oocyte growth GO:0001555 1 0.018
multicellular organism growth GO:0035264 4 0.018
convergent extension GO:0060026 118 0.018
response to organic substance GO:0010033 153 0.018
regulation of ph GO:0006885 3 0.018
embryonic digestive tract development GO:0048566 4 0.018
heart field specification GO:0003128 1 0.018
single fertilization GO:0007338 3 0.017
negative regulation of macromolecule metabolic process GO:0010605 76 0.017
positive regulation of cytokine production GO:0001819 2 0.017
immune response GO:0006955 28 0.017
phosphate containing compound metabolic process GO:0006796 108 0.017
defense response GO:0006952 47 0.017
positive regulation of camp metabolic process GO:0030816 2 0.017
morphogenesis of an epithelium GO:0002009 333 0.016
regulation of protein metabolic process GO:0051246 56 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
positive regulation of transport GO:0051050 2 0.016
eye morphogenesis GO:0048592 144 0.016
heart development GO:0007507 313 0.016
intracellular signal transduction GO:0035556 85 0.016
radial glial cell division in forebrain GO:0021864 1 0.016
liver development GO:0001889 96 0.016
cellular protein metabolic process GO:0044267 129 0.016
wnt signaling pathway GO:0016055 80 0.015
regulation of inflammatory response GO:0050727 2 0.015
cellular localization GO:0051641 97 0.015
positive regulation of gene expression GO:0010628 71 0.015
cellular response to xenobiotic stimulus GO:0071466 35 0.015
macromolecule localization GO:0033036 54 0.015
developmental growth GO:0048589 166 0.015
Zebrafish
specification of organ identity GO:0010092 2 0.015
metal ion transport GO:0030001 58 0.015
skeletal muscle tissue development GO:0007519 67 0.015
gtp catabolic process GO:0006184 2 0.014
single organism localization GO:1902578 225 0.014
regulation of cell motility GO:2000145 46 0.014
transmembrane transport GO:0055085 120 0.014
angiogenesis GO:0001525 158 0.014
gene silencing by rna GO:0031047 4 0.014
retina development in camera type eye GO:0060041 146 0.014
regulation of oocyte development GO:0060281 3 0.014
eye development GO:0001654 277 0.013
response to endogenous stimulus GO:0009719 83 0.013
embryonic organ development GO:0048568 381 0.013
multicellular organismal reproductive process GO:0048609 35 0.013
cell fate specification GO:0001708 68 0.013
protein metabolic process GO:0019538 183 0.013
cell morphogenesis GO:0000902 289 0.013
Zebrafish
digestive tract development GO:0048565 265 0.013
sister chromatid segregation GO:0000819 6 0.013
posttranscriptional gene silencing GO:0016441 3 0.012
single organism cellular localization GO:1902580 46 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
cation transport GO:0006812 81 0.012
regulation of cellular component organization GO:0051128 86 0.012
regulation of multicellular organismal process GO:0051239 277 0.012
camera type eye development GO:0043010 222 0.012
bicarbonate transport GO:0015701 4 0.012
positive regulation of cell division GO:0051781 2 0.012
regulation of phosphorus metabolic process GO:0051174 43 0.012
dsrna fragmentation GO:0031050 1 0.012
negative regulation of reproductive process GO:2000242 3 0.012
negative regulation of multi organism process GO:0043901 3 0.012
rna metabolic process GO:0016070 219 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
sensory organ development GO:0007423 393 0.012
germ line stem cell maintenance GO:0030718 2 0.012
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.012
female gamete generation GO:0007292 14 0.012
cell migration involved in gastrulation GO:0042074 79 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
chordate embryonic development GO:0043009 271 0.011
specification of organ position GO:0010159 3 0.011
spemann organizer formation GO:0060061 10 0.011
positive regulation of biological process GO:0048518 253 0.011
muscle structure development GO:0061061 196 0.011
axial mesoderm formation GO:0048320 4 0.011
regulation of behavior GO:0050795 24 0.011
regulation of gtpase activity GO:0043087 2 0.011
bone remodeling GO:0046849 2 0.011
exocytosis GO:0006887 1 0.011
cellular response to oxygen levels GO:0071453 1 0.011
production of small rna involved in gene silencing by rna GO:0070918 1 0.011
regulation of establishment of protein localization GO:0070201 4 0.011
centrosome organization GO:0051297 1 0.011
response to external biotic stimulus GO:0043207 97 0.011
negative regulation of signaling GO:0023057 96 0.011
glycolipid biosynthetic process GO:0009247 1 0.011
positive regulation of biosynthetic process GO:0009891 68 0.011
dna templated transcription initiation GO:0006352 1 0.011
nuclear division GO:0000280 23 0.011
axial mesodermal cell fate specification GO:0048327 3 0.011
regulation of cellular component movement GO:0051270 55 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
regulation of apoptotic process GO:0042981 98 0.011
bmp signaling pathway involved in heart jogging GO:0003303 14 0.011
determination of left right symmetry GO:0007368 179 0.011
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.011
regulation of embryonic development GO:0045995 47 0.011
regulation of wnt signaling pathway GO:0030111 53 0.010
cytoplasm organization GO:0007028 4 0.010
protein complex subunit organization GO:0071822 46 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.010
localization of cell GO:0051674 244 0.010
negative regulation of defense response GO:0031348 2 0.010

dnd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010