Danio rerio

0 known processes

ptplad1

protein tyrosine phosphatase-like A domain containing 1

(Aliases: HACD,zgc:63632,MGC63632)

ptplad1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular process GO:0048523 283 0.079
response to chemical GO:0042221 320 0.065
signal transduction GO:0007165 455 0.062
regulation of signal transduction GO:0009966 225 0.060
long chain fatty acid metabolic process GO:0001676 1 0.059
multicellular organism growth GO:0035264 4 0.058
establishment of localization GO:0051234 244 0.058
larval development GO:0002164 2 0.056
synaptic vesicle transport GO:0048489 1 0.056
response to stress GO:0006950 263 0.056
protein metabolic process GO:0019538 183 0.051
cellular amine metabolic process GO:0044106 2 0.048
adult behavior GO:0030534 2 0.046
organic substance biosynthetic process GO:1901576 289 0.040
cellular ketone metabolic process GO:0042180 11 0.039
proteasomal protein catabolic process GO:0010498 2 0.036
lipid storage GO:0019915 1 0.036
multicellular organismal response to stress GO:0033555 2 0.035
neurotransmitter transport GO:0006836 2 0.035
peptide transport GO:0015833 1 0.034
regulation of biological quality GO:0065008 263 0.033
positive regulation of cellular component biogenesis GO:0044089 3 0.033
hormone transport GO:0009914 2 0.032
hormone secretion GO:0046879 2 0.032
regulation of binding GO:0051098 3 0.032
phosphorus metabolic process GO:0006793 109 0.031
cellular response to external stimulus GO:0071496 2 0.031
regulation of signaling GO:0023051 235 0.031
organelle organization GO:0006996 227 0.031
oxoacid metabolic process GO:0043436 31 0.031
cellular macromolecule metabolic process GO:0044260 391 0.031
positive regulation of transport GO:0051050 2 0.030
regulation of cellular amino acid metabolic process GO:0006521 0 0.029
biosynthetic process GO:0009058 294 0.029
negative regulation of protein kinase activity GO:0006469 4 0.029
amine metabolic process GO:0009308 2 0.029
peptidyl serine phosphorylation GO:0018105 1 0.029
single organism biosynthetic process GO:0044711 71 0.028
localization of cell GO:0051674 244 0.028
regulation of neurotransmitter transport GO:0051588 1 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.027
cellular protein metabolic process GO:0044267 129 0.027
vasculature development GO:0001944 278 0.027
regulation of response to stimulus GO:0048583 269 0.026
regulation of cell communication GO:0010646 232 0.026
cellular protein modification process GO:0006464 100 0.026
cell morphogenesis GO:0000902 289 0.026
regulation of ion transmembrane transporter activity GO:0032412 2 0.025
negative regulation of protein phosphorylation GO:0001933 4 0.025
pigment granule localization GO:0051875 25 0.025
embryonic organ development GO:0048568 381 0.025
homeostatic process GO:0042592 142 0.025
cellular biosynthetic process GO:0044249 286 0.025
exocytosis GO:0006887 1 0.025
cell migration GO:0016477 237 0.025
ribonucleoside monophosphate catabolic process GO:0009158 4 0.025
response to organic substance GO:0010033 153 0.024
regulation of protein transport GO:0051223 3 0.024
regulation of multicellular organismal process GO:0051239 277 0.024
homeostasis of number of cells GO:0048872 62 0.024
intracellular signal transduction GO:0035556 85 0.024
positive regulation of secretion by cell GO:1903532 1 0.024
nucleocytoplasmic transport GO:0006913 4 0.024
regulation of multicellular organism growth GO:0040014 4 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
purine nucleoside monophosphate catabolic process GO:0009128 4 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
single organism metabolic process GO:0044710 217 0.022
cellular response to chemical stimulus GO:0070887 157 0.022
carboxylic acid metabolic process GO:0019752 22 0.022
macromolecule biosynthetic process GO:0009059 227 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
negative regulation of kinase activity GO:0033673 4 0.022
regulation of cytoplasmic transport GO:1903649 4 0.022
generation of neurons GO:0048699 385 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
small molecule metabolic process GO:0044281 77 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
compound eye development GO:0048749 2 0.021
regulation of reproductive process GO:2000241 4 0.021
i kappab kinase nf kappab signaling GO:0007249 4 0.021
maintenance of location GO:0051235 4 0.021
synaptic vesicle localization GO:0097479 1 0.021
negative regulation of mapk cascade GO:0043409 4 0.021
system process GO:0003008 185 0.021
hepaticobiliary system development GO:0061008 98 0.021
regulation of response to extracellular stimulus GO:0032104 1 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
neurotransmitter secretion GO:0007269 2 0.020
growth GO:0040007 174 0.020
transport GO:0006810 220 0.020
establishment of localization in cell GO:0051649 77 0.019
macromolecule modification GO:0043412 111 0.019
regulation of intracellular protein transport GO:0033157 3 0.019
cell part morphogenesis GO:0032990 246 0.019
cellular component movement GO:0006928 335 0.019
regulation of cytokine production GO:0001817 3 0.019
regulation of programmed cell death GO:0043067 101 0.019
peptidyl serine modification GO:0018209 2 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
nucleoside monophosphate catabolic process GO:0009125 4 0.019
cell projection organization GO:0030030 284 0.019
death GO:0016265 121 0.019
regulation of transmembrane transporter activity GO:0022898 2 0.019
adherens junction organization GO:0034332 4 0.019
phagocytosis GO:0006909 3 0.018
heart development GO:0007507 313 0.018
regulation of metal ion transport GO:0010959 4 0.018
cell projection assembly GO:0030031 64 0.018
response to external stimulus GO:0009605 264 0.018
heterocycle biosynthetic process GO:0018130 215 0.018
axonogenesis GO:0007409 152 0.018
protein modification process GO:0036211 100 0.018
protein localization to nucleus GO:0034504 3 0.018
carbohydrate biosynthetic process GO:0016051 1 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
synaptic growth at neuromuscular junction GO:0051124 2 0.017
aging GO:0007568 2 0.017
negative regulation of biological process GO:0048519 304 0.017
positive regulation of map kinase activity GO:0043406 3 0.017
regulation of neurotransmitter secretion GO:0046928 1 0.017
positive regulation of secretion GO:0051047 1 0.017
atp catabolic process GO:0006200 4 0.017
protein localization to plasma membrane GO:0072659 1 0.017
regulation of nitrogen compound metabolic process GO:0051171 251 0.017
meiotic nuclear division GO:0007126 4 0.017
response to uv GO:0009411 3 0.017
fatty acid biosynthetic process GO:0006633 4 0.017
regulation of response to nutrient levels GO:0032107 1 0.017
organic acid metabolic process GO:0006082 31 0.016
embryonic hemopoiesis GO:0035162 53 0.016
cellular response to starvation GO:0009267 1 0.016
cell substrate junction assembly GO:0007044 2 0.016
response to nutrient GO:0007584 3 0.016
determination of left right symmetry GO:0007368 179 0.016
regulation of transporter activity GO:0032409 2 0.016
alcohol biosynthetic process GO:0046165 2 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.016
regulation of protein complex assembly GO:0043254 3 0.016
response to carbohydrate GO:0009743 3 0.016
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
regulation of cell shape GO:0008360 1 0.015
peptidyl threonine phosphorylation GO:0018107 1 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
programmed cell death GO:0012501 119 0.015
cell death GO:0008219 121 0.015
regulation of muscle contraction GO:0006937 3 0.015
protein import into nucleus GO:0006606 3 0.015
meiotic cell cycle process GO:1903046 3 0.015
positive regulation of catabolic process GO:0009896 4 0.015
cellular component morphogenesis GO:0032989 336 0.015
mitochondrion organization GO:0007005 4 0.015
cellular response to nutrient levels GO:0031669 2 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
digestive system development GO:0055123 289 0.015
gene expression GO:0010467 252 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
regulation of developmental process GO:0050793 247 0.015
regulation of protein polymerization GO:0032271 2 0.015
rna transport GO:0050658 2 0.015
protein dephosphorylation GO:0006470 3 0.015
establishment of synaptic vesicle localization GO:0097480 1 0.015
regulation of inflammatory response GO:0050727 2 0.014
cellular protein catabolic process GO:0044257 4 0.014
g2 m transition of mitotic cell cycle GO:0000086 4 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
axon cargo transport GO:0008088 2 0.014
sensory organ morphogenesis GO:0090596 200 0.014
regulation of tube size GO:0035150 2 0.014
regulation of biosynthetic process GO:0009889 250 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
protein import GO:0017038 3 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
cellular lipid metabolic process GO:0044255 36 0.014
protein secretion GO:0009306 1 0.014
positive regulation of cell cycle GO:0045787 3 0.014
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.014
regulation of cell activation GO:0050865 1 0.014
secondary metabolic process GO:0019748 3 0.014
single organism localization GO:1902578 225 0.014
regulation of reactive oxygen species metabolic process GO:2000377 2 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
heart morphogenesis GO:0003007 156 0.014
tube morphogenesis GO:0035239 349 0.014
epithelial tube morphogenesis GO:0060562 148 0.014
negative regulation of cell communication GO:0010648 96 0.014
regulation of synapse organization GO:0050807 3 0.014
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.014
regulation of calcium ion transport GO:0051924 2 0.014
establishment of pigment granule localization GO:0051905 22 0.014
regulation of cell motility GO:2000145 46 0.014
positive regulation of biological process GO:0048518 253 0.013
regulation of synapse assembly GO:0051963 3 0.013
epithelial cell morphogenesis GO:0003382 2 0.013
long chain fatty acid biosynthetic process GO:0042759 1 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
morphogenesis of an epithelium GO:0002009 333 0.013
actin filament based process GO:0030029 64 0.013
glycerophospholipid biosynthetic process GO:0046474 1 0.013
tissue remodeling GO:0048771 4 0.013
actin filament polymerization GO:0030041 2 0.013
protein polymerization GO:0051258 4 0.013
nuclear transport GO:0051169 4 0.013
regulation of cell projection assembly GO:0060491 4 0.013
synaptic vesicle recycling GO:0036465 1 0.013
regulation of cell migration GO:0030334 40 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
smooth muscle contraction GO:0006939 2 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
single fertilization GO:0007338 3 0.013
ovulation cycle GO:0042698 2 0.013
transmission of nerve impulse GO:0019226 19 0.013
cytoskeleton dependent intracellular transport GO:0030705 10 0.013
negative regulation of metabolic process GO:0009892 86 0.013
single organism organelle organization GO:1902589 199 0.012
nucleic acid transport GO:0050657 2 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
neuronal action potential GO:0019228 18 0.012
ovulation cycle process GO:0022602 2 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
muscle cell differentiation GO:0042692 139 0.012
blood vessel morphogenesis GO:0048514 216 0.012
cellular component disassembly GO:0022411 1 0.012
central nervous system development GO:0007417 387 0.012
lamellipodium organization GO:0097581 1 0.012
digestive tract morphogenesis GO:0048546 231 0.012
establishment of melanosome localization GO:0032401 19 0.012
response to corticosteroid GO:0031960 1 0.012
response to other organism GO:0051707 97 0.012
melanosome transport GO:0032402 19 0.012
nuclear import GO:0051170 3 0.012
neuron development GO:0048666 262 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
multicellular organismal signaling GO:0035637 22 0.012
cellular lipid catabolic process GO:0044242 3 0.012
regulation of localization GO:0032879 104 0.012
macromolecular complex disassembly GO:0032984 1 0.012
nucleobase containing compound transport GO:0015931 2 0.012
embryonic heart tube morphogenesis GO:0003143 108 0.012
cellular amide metabolic process GO:0043603 4 0.012
hemopoiesis GO:0030097 183 0.012
response to antibiotic GO:0046677 1 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
meiotic chromosome segregation GO:0045132 3 0.011
regulation of primary metabolic process GO:0080090 311 0.011
centrosome localization GO:0051642 1 0.011
neuron differentiation GO:0030182 353 0.011
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
cell substrate adhesion GO:0031589 4 0.011
activation of mapk activity GO:0000187 3 0.011
ion transport GO:0006811 114 0.011
pole plasm assembly GO:0007315 4 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
regulation of calcium ion dependent exocytosis GO:0017158 1 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
carbon dioxide transport GO:0015670 3 0.011
regulation of cell substrate adhesion GO:0010810 1 0.011
response to endogenous stimulus GO:0009719 83 0.011
gland development GO:0048732 143 0.011
single organism nuclear import GO:1902593 3 0.011
positive regulation of cellular process GO:0048522 201 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
regulation of apoptotic process GO:0042981 98 0.011
cellular modified amino acid metabolic process GO:0006575 3 0.011
regulation of protein binding GO:0043393 3 0.011
establishment of protein localization to organelle GO:0072594 4 0.011
microtubule based process GO:0007017 60 0.011
regulation of blood vessel size GO:0050880 2 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
liver development GO:0001889 96 0.011
positive regulation of lipid metabolic process GO:0045834 1 0.011
er nucleus signaling pathway GO:0006984 2 0.011
positive regulation of cytokine production GO:0001819 2 0.011
negative regulation of signaling GO:0023057 96 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
response to monosaccharide GO:0034284 3 0.011
transmembrane transport GO:0055085 120 0.010
erk1 and erk2 cascade GO:0070371 4 0.010
cellular aromatic compound metabolic process GO:0006725 295 0.010
response to hexose GO:0009746 3 0.010
cell motility GO:0048870 244 0.010
synaptic vesicle endocytosis GO:0048488 1 0.010
trabecula morphogenesis GO:0061383 2 0.010
metal ion transport GO:0030001 58 0.010
response to glucose GO:0009749 3 0.010
small molecule catabolic process GO:0044282 3 0.010
mesoderm development GO:0007498 88 0.010
modification dependent protein catabolic process GO:0019941 3 0.010
response to abiotic stimulus GO:0009628 122 0.010
nitrogen compound metabolic process GO:0006807 319 0.010
protein targeting to nucleus GO:0044744 3 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010
membrane lipid biosynthetic process GO:0046467 2 0.010
organelle assembly GO:0070925 110 0.010
mitotic cell cycle GO:0000278 64 0.010

ptplad1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
disease of cellular proliferation DOID:14566 0 0.020
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014
cancer DOID:162 0 0.014
nervous system disease DOID:863 0 0.014
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
musculoskeletal system disease DOID:17 0 0.010