Danio rerio

72 known processes

spi1

spleen focus forming virus (SFFV) proviral integration oncogene spi1

(Aliases: cb1086,si:by184l24.2,pu1,pu.1,sfpi1)

spi1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of immune system process GO:0002682 34 0.991
macrophage chemotaxis GO:0048246 3 0.880
cell migration GO:0016477 237 0.855
myeloid leukocyte differentiation GO:0002573 15 0.854
myoblast fusion GO:0007520 10 0.811
regulation of metabolic process GO:0019222 359 0.800
immune effector process GO:0002252 23 0.741
immune system process GO:0002376 241 0.741
cell motility GO:0048870 244 0.736
inflammatory response GO:0006954 8 0.728
angiogenesis GO:0001525 158 0.725
Mouse
regulation of primary metabolic process GO:0080090 311 0.717
Human Mouse Rat
response to chemical GO:0042221 320 0.702
Rat
hydrogen peroxide metabolic process GO:0042743 2 0.654
cellular ketone metabolic process GO:0042180 11 0.652
positive regulation of immune system process GO:0002684 17 0.651
immune system development GO:0002520 191 0.646
response to other organism GO:0051707 97 0.645
gland development GO:0048732 143 0.643
regulation of cellular biosynthetic process GO:0031326 245 0.601
Human Mouse Rat
defense response GO:0006952 47 0.540
granulocyte migration GO:0097530 11 0.536
striated muscle cell differentiation GO:0051146 129 0.530
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.504
Human Mouse Rat
heterocycle biosynthetic process GO:0018130 215 0.494
Human Mouse Rat
cellular macromolecule metabolic process GO:0044260 391 0.471
Human Mouse Rat
brain development GO:0007420 293 0.443
myeloid leukocyte migration GO:0097529 12 0.429
negative regulation of biological process GO:0048519 304 0.402
nucleic acid metabolic process GO:0090304 244 0.398
Human Mouse Rat
positive regulation of myeloid cell differentiation GO:0045639 2 0.396
response to biotic stimulus GO:0009607 97 0.385
negative regulation of signal transduction GO:0009968 94 0.383
multicellular organismal metabolic process GO:0044236 2 0.382
small molecule metabolic process GO:0044281 77 0.379
chemotaxis GO:0006935 104 0.363
positive regulation of neural retina development GO:0061075 1 0.362
liver development GO:0001889 96 0.359
response to external stimulus GO:0009605 264 0.359
cellular response to lipopolysaccharide GO:0071222 3 0.345
superoxide metabolic process GO:0006801 2 0.342
gastrulation GO:0007369 208 0.341
positive regulation of cell activation GO:0050867 1 0.335
positive regulation of chronic inflammatory response GO:0002678 1 0.332
leukocyte migration GO:0050900 15 0.327
leukocyte chemotaxis GO:0030595 12 0.326
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.304
regulation of cell activation GO:0050865 1 0.294
hematopoietic stem cell migration GO:0035701 4 0.287
regulation of myeloid leukocyte differentiation GO:0002761 5 0.285
regulation of inflammatory response GO:0050727 2 0.282
cellular response to molecule of bacterial origin GO:0071219 3 0.281
organonitrogen compound metabolic process GO:1901564 74 0.278
sensory organ development GO:0007423 393 0.277
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.259
macrophage differentiation GO:0030225 7 0.258
hepaticobiliary system development GO:0061008 98 0.254
digestive system development GO:0055123 289 0.251
larval development GO:0002164 2 0.243
defense response to fungus GO:0050832 2 0.236
cell chemotaxis GO:0060326 17 0.233
negative regulation of granulocyte chemotaxis GO:0071623 3 0.231
regulation of chronic inflammatory response GO:0002676 1 0.230
cell part morphogenesis GO:0032990 246 0.228
regulation of rna metabolic process GO:0051252 224 0.226
Human Mouse Rat
cellular component assembly GO:0022607 170 0.225
cellular macromolecule biosynthetic process GO:0034645 224 0.224
Human Mouse Rat
response to fungus GO:0009620 25 0.223
regulation of protein complex assembly GO:0043254 3 0.219
positive regulation of cellular component biogenesis GO:0044089 3 0.219
digestive tract development GO:0048565 265 0.213
carboxylic acid metabolic process GO:0019752 22 0.213
positive regulation of protein complex assembly GO:0031334 2 0.210
rna biosynthetic process GO:0032774 181 0.208
Human Mouse Rat
transcription dna templated GO:0006351 181 0.205
Human Mouse Rat
developmental growth GO:0048589 166 0.203
neuron migration GO:0001764 22 0.202
axonal defasciculation GO:0007414 2 0.201
homeostatic process GO:0042592 142 0.200
response to bacterium GO:0009617 58 0.197
locomotion GO:0040011 313 0.191
regulation of leukocyte differentiation GO:1902105 5 0.188
regulation of immune response GO:0050776 14 0.182
cellular component morphogenesis GO:0032989 336 0.178
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.178
Human Mouse Rat
response to organic substance GO:0010033 153 0.173
Rat
oxoacid metabolic process GO:0043436 31 0.168
actin polymerization or depolymerization GO:0008154 2 0.167
organic acid metabolic process GO:0006082 31 0.166
axon guidance GO:0007411 86 0.165
response to endogenous stimulus GO:0009719 83 0.163
hemopoiesis GO:0030097 183 0.163
positive regulation of macrophage chemotaxis GO:0010759 1 0.162
actin filament based process GO:0030029 64 0.162
positive regulation of cellular metabolic process GO:0031325 94 0.161
Human Mouse Rat
regulation of cell differentiation GO:0045595 142 0.161
cell activation GO:0001775 16 0.159
Mouse
negative regulation of cell communication GO:0010648 96 0.159
response to stress GO:0006950 263 0.157
response to external biotic stimulus GO:0043207 97 0.156
positive regulation of multicellular organismal process GO:0051240 52 0.154
positive regulation of cellular process GO:0048522 201 0.154
Human Mouse Rat
growth GO:0040007 174 0.154
positive regulation of immune response GO:0050778 11 0.153
mononuclear cell proliferation GO:0032943 1 0.153
cellular response to chemical stimulus GO:0070887 157 0.151
Rat
positive regulation of cellular amine metabolic process GO:0033240 0 0.149
regulation of multicellular organismal process GO:0051239 277 0.149
positive regulation of immune effector process GO:0002699 3 0.148
response to lipid GO:0033993 60 0.148
negative regulation of chemotaxis GO:0050922 4 0.148
regulation of biosynthetic process GO:0009889 250 0.146
Human Mouse Rat
regulation of neural retina development GO:0061074 2 0.144
smooth muscle contraction GO:0006939 2 0.143
single organism metabolic process GO:0044710 217 0.139
Human
response to wounding GO:0009611 116 0.139
regulation of defense response GO:0031347 14 0.138
g2 m transition of mitotic cell cycle GO:0000086 4 0.138
regulation of nervous system development GO:0051960 90 0.138
regulation of hydrogen peroxide metabolic process GO:0010310 1 0.135
positive regulation of biological process GO:0048518 253 0.132
regulation of macromolecule biosynthetic process GO:0010556 225 0.131
Human Mouse Rat
negative regulation of cellular process GO:0048523 283 0.129
cell projection morphogenesis GO:0048858 244 0.128
lymph vessel morphogenesis GO:0036303 25 0.128
central nervous system development GO:0007417 387 0.128
negative regulation of neutrophil chemotaxis GO:0090024 3 0.125
leukocyte differentiation GO:0002521 25 0.124
regulation of mononuclear cell migration GO:0071675 1 0.124
negative regulation of leukocyte chemotaxis GO:0002689 3 0.122
tube morphogenesis GO:0035239 349 0.120
Mouse
spermatid development GO:0007286 2 0.114
blood vessel morphogenesis GO:0048514 216 0.112
Mouse
defense response to other organism GO:0098542 33 0.111
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.111
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.108
Human Mouse Rat
single organism organelle organization GO:1902589 199 0.108
Human
positive regulation of developmental process GO:0051094 50 0.106
regulation of gene expression GO:0010468 265 0.104
regulation of nitrogen compound metabolic process GO:0051171 251 0.104
Human Mouse Rat
osteoclast development GO:0036035 1 0.102
cell morphogenesis GO:0000902 289 0.101
synaptic growth at neuromuscular junction GO:0051124 2 0.100
neutrophil chemotaxis GO:0030593 10 0.098
cellular component movement GO:0006928 335 0.098
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.098
stem cell proliferation GO:0072089 4 0.098
amine metabolic process GO:0009308 2 0.097
regulation of cellular component movement GO:0051270 55 0.096
organic cyclic compound metabolic process GO:1901360 301 0.096
Human Mouse Rat
blood vessel development GO:0001568 246 0.095
Mouse
organic substance biosynthetic process GO:1901576 289 0.094
Human Mouse Rat
nucleobase containing compound biosynthetic process GO:0034654 205 0.093
Human Mouse Rat
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.093
spermatogenesis GO:0007283 7 0.092
positive regulation of apoptotic signaling pathway GO:2001235 1 0.091
regulation of growth GO:0040008 42 0.091
positive regulation of molecular function GO:0044093 33 0.091
interspecies interaction between organisms GO:0044419 4 0.090
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.090
biosynthetic process GO:0009058 294 0.089
Human Mouse Rat
positive regulation of cellular extravasation GO:0002693 1 0.088
actin filament polymerization GO:0030041 2 0.088
regulation of leukocyte migration GO:0002685 8 0.086
regulation of cytokine production GO:0001817 3 0.086
phagocytosis GO:0006909 3 0.084
lymphocyte proliferation GO:0046651 1 0.083
cellular nitrogen compound biosynthetic process GO:0044271 218 0.083
Human Mouse Rat
positive regulation of rna metabolic process GO:0051254 59 0.082
Human Mouse Rat
regulation of nucleic acid templated transcription GO:1903506 213 0.081
Human Mouse Rat
response to molecule of bacterial origin GO:0002237 14 0.081
regulation of rna biosynthetic process GO:2001141 213 0.081
Human Mouse Rat
regulation of response to stimulus GO:0048583 269 0.080
epidermis development GO:0008544 48 0.078
retinal ganglion cell axon guidance GO:0031290 35 0.078
neuron development GO:0048666 262 0.077
regeneration GO:0031099 91 0.076
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.076
monocyte differentiation GO:0030224 2 0.075
spindle assembly GO:0051225 2 0.073
neuroepithelial cell differentiation GO:0060563 26 0.073
cellular amino acid metabolic process GO:0006520 7 0.072
regulation of cellular response to oxidative stress GO:1900407 2 0.071
positive regulation of cytoskeleton organization GO:0051495 3 0.070
positive regulation of metabolic process GO:0009893 108 0.070
homeostasis of number of cells within a tissue GO:0048873 4 0.070
protein complex assembly GO:0006461 30 0.069
gastrulation with mouth forming second GO:0001702 44 0.069
neutrophil migration GO:1990266 10 0.068
collagen metabolic process GO:0032963 2 0.067
positive regulation of macromolecule metabolic process GO:0010604 93 0.067
reactive oxygen species biosynthetic process GO:1903409 1 0.066
positive chemotaxis GO:0050918 5 0.066
generation of neurons GO:0048699 385 0.066
sequestering of calcium ion GO:0051208 3 0.065
negative regulation of synapse assembly GO:0051964 2 0.065
lymphocyte homeostasis GO:0002260 1 0.064
regulation of stem cell proliferation GO:0072091 2 0.064
regulation of synapse assembly GO:0051963 3 0.063
reactive oxygen species metabolic process GO:0072593 6 0.063
oxidation reduction process GO:0055114 41 0.063
vasculature development GO:0001944 278 0.063
Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.062
Human Mouse Rat
negative regulation of response to stimulus GO:0048585 104 0.062
cellular response to endogenous stimulus GO:0071495 68 0.060
response to yeast GO:0001878 23 0.060
organelle fusion GO:0048284 3 0.060
positive regulation of positive chemotaxis GO:0050927 4 0.059
cellular protein modification process GO:0006464 100 0.059
Human
nucleobase containing compound metabolic process GO:0006139 274 0.059
Human Mouse Rat
cell surface receptor signaling pathway GO:0007166 325 0.059
regulation of multicellular organismal development GO:2000026 223 0.059
regulation of cellular extravasation GO:0002691 1 0.059
negative regulation of multicellular organismal process GO:0051241 69 0.058
neuron projection development GO:0031175 180 0.058
regulation of immune effector process GO:0002697 5 0.058
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.057
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.057
cellular response to organic substance GO:0071310 105 0.057
Rat
positive regulation of cell differentiation GO:0045597 30 0.056
nitrogen compound metabolic process GO:0006807 319 0.056
Human Mouse Rat
endosomal transport GO:0016197 2 0.055
dna modification GO:0006304 8 0.055
Human
leukocyte activation GO:0045321 12 0.055
Mouse
regulation of cell shape GO:0008360 1 0.055
immunoglobulin mediated immune response GO:0016064 3 0.054
cell morphogenesis involved in differentiation GO:0000904 195 0.054
muscle organ development GO:0007517 101 0.054
death GO:0016265 121 0.053
Mouse
megakaryocyte differentiation GO:0030219 1 0.053
camera type eye development GO:0043010 222 0.052
leukocyte proliferation GO:0070661 1 0.052
regulation of positive chemotaxis GO:0050926 4 0.052
actin cytoskeleton organization GO:0030036 63 0.051
type i interferon production GO:0032606 2 0.051
response to drug GO:0042493 3 0.051
protein complex subunit organization GO:0071822 46 0.051
negative regulation of leukocyte migration GO:0002686 3 0.050
negative regulation of signaling GO:0023057 96 0.050
negative regulation of immune system process GO:0002683 7 0.050
cardiogenic plate morphogenesis GO:0003142 1 0.050
spermatid differentiation GO:0048515 2 0.049
homeostasis of number of cells GO:0048872 62 0.049
macromolecular complex subunit organization GO:0043933 74 0.049
Human
cellular protein metabolic process GO:0044267 129 0.048
Human
cellular aromatic compound metabolic process GO:0006725 295 0.048
Human Mouse Rat
regulation of myotube differentiation GO:0010830 2 0.048
transport GO:0006810 220 0.048
digestive tract morphogenesis GO:0048546 231 0.048
regulation of cardiac muscle tissue development GO:0055024 1 0.048
positive regulation of response to external stimulus GO:0032103 9 0.048
tissue regeneration GO:0042246 74 0.046
organelle organization GO:0006996 227 0.046
Human
dorsal aorta morphogenesis GO:0035912 3 0.046
ameboidal type cell migration GO:0001667 143 0.046
head development GO:0060322 303 0.046
protein metabolic process GO:0019538 183 0.045
Human
positive regulation of gene expression GO:0010628 71 0.045
regulation of response to external stimulus GO:0032101 31 0.045
osteoclast differentiation GO:0030316 1 0.045
muscle structure development GO:0061061 196 0.045
lymphoid lineage cell migration GO:0097534 4 0.044
lymph vessel development GO:0001945 27 0.044
positive regulation of locomotion GO:0040017 14 0.044
negative regulation of protein phosphorylation GO:0001933 4 0.043
regulation of cellular amine metabolic process GO:0033238 0 0.043
chemical homeostasis GO:0048878 49 0.043
taxis GO:0042330 109 0.043
regulation of protein polymerization GO:0032271 2 0.043
regulation of erythrocyte differentiation GO:0045646 2 0.042
regulation of cellular amino acid metabolic process GO:0006521 0 0.042
cellular response to biotic stimulus GO:0071216 3 0.042
regulation of developmental process GO:0050793 247 0.042
regulation of neutrophil migration GO:1902622 6 0.041
cellular response to hormone stimulus GO:0032870 39 0.041
multi organism process GO:0051704 134 0.041
positive regulation of cytokine production GO:0001819 2 0.041
cytosolic calcium ion transport GO:0060401 3 0.041
neuron differentiation GO:0030182 353 0.041
regulation of phosphate metabolic process GO:0019220 43 0.041
central nervous system neuron differentiation GO:0021953 74 0.041
regulation of sequestering of calcium ion GO:0051282 4 0.040
cell migration to the midline involved in heart development GO:0003318 12 0.040
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.040
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.040
eye development GO:0001654 277 0.039
response to oxygen containing compound GO:1901700 55 0.039
Rat
epithelial cell migration GO:0010631 25 0.039
sprouting angiogenesis GO:0002040 53 0.039
hematopoietic or lymphoid organ development GO:0048534 191 0.038
myeloid cell differentiation GO:0030099 86 0.037
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.037
regulation of cell death GO:0010941 103 0.037
cellular component biogenesis GO:0044085 178 0.037
cation homeostasis GO:0055080 33 0.037
eye morphogenesis GO:0048592 144 0.036
positive regulation of gliogenesis GO:0014015 2 0.036
positive regulation of biosynthetic process GO:0009891 68 0.036
Human Mouse Rat
myotube differentiation GO:0014902 45 0.036
lymphocyte activation GO:0046649 10 0.036
Mouse
epidermal cell differentiation GO:0009913 36 0.036
positive regulation of response to stimulus GO:0048584 80 0.036
nucleic acid templated transcription GO:0097659 181 0.036
Human Mouse Rat
erk1 and erk2 cascade GO:0070371 4 0.035
negative regulation of metabolic process GO:0009892 86 0.035
Human Mouse Rat
macromolecule biosynthetic process GO:0009059 227 0.035
Human Mouse Rat
multicellular organismal macromolecule metabolic process GO:0044259 2 0.035
regulation of cell proliferation GO:0042127 37 0.034
cell migration involved in heart development GO:0060973 22 0.034
i kappab kinase nf kappab signaling GO:0007249 4 0.034
t cell activation GO:0042110 6 0.034
macromolecular complex assembly GO:0065003 35 0.034
cellular amine metabolic process GO:0044106 2 0.033
epithelium migration GO:0090132 25 0.033
ectodermal placode morphogenesis GO:0071697 32 0.033
protein polymerization GO:0051258 4 0.033
fatty acid metabolic process GO:0006631 5 0.033
regulation of anatomical structure size GO:0090066 33 0.033
syncytium formation GO:0006949 12 0.032
striated muscle tissue development GO:0014706 110 0.032
axonogenesis GO:0007409 152 0.032
organelle assembly GO:0070925 110 0.032
positive regulation of protein polymerization GO:0032273 2 0.032
regulation of developmental growth GO:0048638 38 0.032
embryonic skeletal system morphogenesis GO:0048704 93 0.032
regulation of homeostatic process GO:0032844 9 0.032
vasculogenesis GO:0001570 41 0.031
regulation of cell communication GO:0010646 232 0.031
dorsal aorta development GO:0035907 4 0.031
response to organonitrogen compound GO:0010243 12 0.031
lymphangiogenesis GO:0001946 25 0.031
regulation of biological quality GO:0065008 263 0.031
protein complex biogenesis GO:0070271 30 0.031
anatomical structure homeostasis GO:0060249 36 0.030
production of molecular mediator of immune response GO:0002440 2 0.030
release of sequestered calcium ion into cytosol GO:0051209 3 0.030
epidermal cell fate specification GO:0009957 4 0.030
regulation of cellular metabolic process GO:0031323 320 0.030
Human Mouse Rat
cognition GO:0050890 1 0.029
heterocycle metabolic process GO:0046483 290 0.029
Human Mouse Rat
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.029
erythrocyte maturation GO:0043249 8 0.029
regulation of cell motility GO:2000145 46 0.029
regulation of cellular component size GO:0032535 30 0.029
hypothalamus cell differentiation GO:0021979 4 0.028
axonal fasciculation GO:0007413 11 0.028
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.028
signal transduction GO:0007165 455 0.028
maintenance of location GO:0051235 4 0.028
regulation of macromolecule metabolic process GO:0060255 317 0.028
actin filament based movement GO:0030048 1 0.028
regulation of multicellular organism growth GO:0040014 4 0.028
regulation of neuron migration GO:2001222 2 0.028
gene expression GO:0010467 252 0.028
endocrine system development GO:0035270 65 0.028
positive regulation of leukocyte differentiation GO:1902107 1 0.028
lens fiber cell morphogenesis GO:0070309 3 0.028
response to amino acid GO:0043200 2 0.027
rna metabolic process GO:0016070 219 0.027
Human Mouse Rat
toll like receptor signaling pathway GO:0002224 4 0.027
regulation of cellular component organization GO:0051128 86 0.027
Human
negative regulation of cytokine production GO:0001818 1 0.027
definitive hemopoiesis GO:0060216 18 0.026
regulation of retina development in camera type eye GO:1902866 2 0.026
antibacterial humoral response GO:0019731 2 0.025
inner ear development GO:0048839 126 0.025
cellular response to estradiol stimulus GO:0071392 1 0.025
cellular response to toxic substance GO:0097237 1 0.025
sequestering of metal ion GO:0051238 3 0.025
cellular amide metabolic process GO:0043603 4 0.025
glial cell fate determination GO:0007403 1 0.025
b cell mediated immunity GO:0019724 3 0.025
response to peptide hormone GO:0043434 6 0.025
neuromuscular junction development GO:0007528 9 0.025
positive regulation of glial cell differentiation GO:0045687 1 0.025
hematopoietic progenitor cell differentiation GO:0002244 23 0.025
Mouse
positive regulation of myeloid leukocyte differentiation GO:0002763 1 0.024
positive regulation of stem cell proliferation GO:2000648 1 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.024
Human Mouse Rat
negative regulation of myeloid leukocyte differentiation GO:0002762 1 0.024
muscle cell differentiation GO:0042692 139 0.024
neuron projection morphogenesis GO:0048812 161 0.024
cell projection organization GO:0030030 284 0.024
cranial ganglion development GO:0061550 3 0.023
cytoskeleton organization GO:0007010 96 0.023
melanocyte migration GO:0097324 4 0.023
endodermal cell differentiation GO:0035987 19 0.023
positive regulation of cellular component movement GO:0051272 11 0.023
regulation of signal transduction GO:0009966 225 0.023
blood circulation GO:0008015 87 0.023
response to hormone GO:0009725 48 0.023
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.023
ectodermal placode formation GO:0060788 26 0.022
regulation of dna methylation GO:0044030 5 0.022
Human
histone h3 k9 methylation GO:0051567 5 0.022
regulation of programmed cell death GO:0043067 101 0.022
cellular response to reactive oxygen species GO:0034614 2 0.022
cardiac cell fate commitment GO:0060911 1 0.022
induction of positive chemotaxis GO:0050930 4 0.022
response to nitrogen compound GO:1901698 19 0.022
regulation of protein phosphorylation GO:0001932 18 0.022
retina morphogenesis in camera type eye GO:0060042 79 0.022
microglia differentiation GO:0014004 1 0.022
negative regulation of kinase activity GO:0033673 4 0.022
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.021
artery morphogenesis GO:0048844 14 0.021
skin development GO:0043588 54 0.021
dna metabolic process GO:0006259 27 0.021
Human
camera type eye morphogenesis GO:0048593 108 0.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.021
carbohydrate homeostasis GO:0033500 1 0.021
tissue migration GO:0090130 37 0.021
humoral immune response GO:0006959 5 0.021
protein oligomerization GO:0051259 7 0.021
spinal cord development GO:0021510 46 0.021
cell substrate adhesion GO:0031589 4 0.020
negative regulation of rna metabolic process GO:0051253 48 0.020
Human Mouse Rat
regulation of bone mineralization GO:0030500 2 0.020
cell migration involved in heart formation GO:0060974 10 0.020
respiratory burst GO:0045730 2 0.020
intestinal epithelial structure maintenance GO:0060729 7 0.020
glial cell differentiation GO:0010001 42 0.020
embryonic organ development GO:0048568 381 0.020
convergent extension involved in gastrulation GO:0060027 71 0.020
positive regulation of secretion GO:0051047 1 0.020
heart valve formation GO:0003188 4 0.020
establishment of localization GO:0051234 244 0.020
adaptive immune response GO:0002250 5 0.020
intestinal epithelial cell differentiation GO:0060575 3 0.019
convergent extension GO:0060026 118 0.019
single organism membrane fusion GO:0044801 2 0.019
regulation of histone methylation GO:0031060 3 0.019
regulation of production of molecular mediator of immune response GO:0002700 1 0.019
epithelial cell morphogenesis GO:0003382 2 0.019
neuromast primordium migration GO:0048883 12 0.019
regulation of tissue remodeling GO:0034103 2 0.019
regulation of oxidative stress induced cell death GO:1903201 2 0.019
xanthophore differentiation GO:0050936 3 0.019
calcium ion transport into cytosol GO:0060402 3 0.019
glial cell fate commitment GO:0021781 6 0.019
granulocyte chemotaxis GO:0071621 11 0.019
cellular nitrogen compound metabolic process GO:0034641 290 0.019
Human Mouse Rat
positive regulation of transport GO:0051050 2 0.018
cellular component maintenance GO:0043954 3 0.018
axon development GO:0061564 166 0.018
regulation of signaling GO:0023051 235 0.018
syncytium formation by plasma membrane fusion GO:0000768 12 0.018
regulation of locomotion GO:0040012 55 0.018
multicellular organism growth GO:0035264 4 0.018
nuclear transport GO:0051169 4 0.018
localization of cell GO:0051674 244 0.017
positive regulation of chemotaxis GO:0050921 5 0.017
protein complex localization GO:0031503 1 0.017
entrainment of circadian clock by photoperiod GO:0043153 1 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.017
Human Mouse Rat
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.017
astrocyte differentiation GO:0048708 1 0.017
response to oxygen radical GO:0000305 2 0.017
embryo development ending in birth or egg hatching GO:0009792 271 0.017
metal ion homeostasis GO:0055065 26 0.017
regulation of organelle organization GO:0033043 29 0.017
Human
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.016
regulation of response to biotic stimulus GO:0002831 2 0.016
innate immune response GO:0045087 13 0.016
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 1 0.016
regulation of epithelial cell proliferation GO:0050678 3 0.016
platelet formation GO:0030220 1 0.016
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.016
lymphoid lineage cell migration into thymus GO:0097535 4 0.016
determination of intestine left right asymmetry GO:0071908 2 0.016
stem cell maintenance GO:0019827 4 0.016
Mouse
cell fate specification GO:0001708 68 0.016
epithelial tube morphogenesis GO:0060562 148 0.016
Mouse
positive regulation of leukocyte migration GO:0002687 2 0.016
lens fiber cell development GO:0070307 3 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
response to dexamethasone GO:0071548 1 0.016
regulation of erk1 and erk2 cascade GO:0070372 4 0.016
morphogenesis of an epithelium GO:0002009 333 0.015
Mouse
response to monosaccharide GO:0034284 3 0.015
internal peptidyl lysine acetylation GO:0018393 2 0.015
Human
macromolecule modification GO:0043412 111 0.015
Human
system process GO:0003008 185 0.015
regulation of cytokine mediated signaling pathway GO:0001959 3 0.015
negative regulation of growth GO:0045926 10 0.015
positive regulation of axon guidance GO:1902669 1 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
negative regulation of leukocyte differentiation GO:1902106 1 0.015
heart contraction GO:0060047 71 0.015
ventricular cardiac muscle tissue development GO:0003229 3 0.015
positive regulation of defense response GO:0031349 9 0.015
positive regulation of inflammatory response GO:0050729 1 0.015
response to hydrogen peroxide GO:0042542 3 0.015
leukocyte homeostasis GO:0001776 2 0.015
cell migration involved in sprouting angiogenesis GO:0002042 8 0.015
epithelial cell differentiation GO:0030855 116 0.015

spi1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.056
immune system disease DOID:2914 0 0.028
disease of metabolism DOID:0014667 0 0.019