Danio rerio

0 known processes

lass5

LAG1 homolog, ceramide synthase 5 (S. cerevisiae)

(Aliases: zgc:63908,fb79b03,wu:fb79b03)

lass5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleobase containing compound metabolic process GO:0006139 274 0.219
organic cyclic compound metabolic process GO:1901360 301 0.209
hematopoietic or lymphoid organ development GO:0048534 191 0.207
regulation of biological quality GO:0065008 263 0.181
digestive tract development GO:0048565 265 0.175
response to drug GO:0042493 3 0.155
immune system process GO:0002376 241 0.154
organic substance biosynthetic process GO:1901576 289 0.142
Human Yeast Mouse
localization of cell GO:0051674 244 0.130
single organism metabolic process GO:0044710 217 0.129
Human Yeast Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.125
small molecule metabolic process GO:0044281 77 0.118
sphingolipid biosynthetic process GO:0030148 2 0.118
Human Yeast Mouse
carbohydrate derivative metabolic process GO:1901135 61 0.113
tube morphogenesis GO:0035239 349 0.109
membrane lipid biosynthetic process GO:0046467 2 0.102
Human Yeast Mouse
larval development GO:0002164 2 0.097
digestive system development GO:0055123 289 0.097
very long chain fatty acid metabolic process GO:0000038 4 0.090
digestive tract morphogenesis GO:0048546 231 0.089
protein targeting to nucleus GO:0044744 3 0.086
cellular nitrogen compound metabolic process GO:0034641 290 0.086
locomotion GO:0040011 313 0.085
Worm
cell migration GO:0016477 237 0.084
single organism biosynthetic process GO:0044711 71 0.084
Human Yeast Mouse
heterocycle metabolic process GO:0046483 290 0.083
nitrogen compound metabolic process GO:0006807 319 0.081
Human Yeast Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.079
modification dependent protein catabolic process GO:0019941 3 0.075
regulation of multicellular organism growth GO:0040014 4 0.074
carboxylic acid metabolic process GO:0019752 22 0.074
cellular aromatic compound metabolic process GO:0006725 295 0.073
establishment of protein localization to organelle GO:0072594 4 0.070
protein polymerization GO:0051258 4 0.069
water homeostasis GO:0030104 4 0.067
cellular nitrogen compound biosynthetic process GO:0044271 218 0.065
immune system development GO:0002520 191 0.065
cytokinesis GO:0000910 3 0.064
very long chain fatty acid biosynthetic process GO:0042761 4 0.064
signal transduction GO:0007165 455 0.064
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.063
cellular ketone metabolic process GO:0042180 11 0.062
negative regulation of biological process GO:0048519 304 0.061
heart development GO:0007507 313 0.060
mitochondrion organization GO:0007005 4 0.060
programmed cell death GO:0012501 119 0.059
lipid storage GO:0019915 1 0.059
cellular protein catabolic process GO:0044257 4 0.058
response to external stimulus GO:0009605 264 0.057
long chain fatty acid metabolic process GO:0001676 1 0.057
eye development GO:0001654 277 0.056
maintenance of location GO:0051235 4 0.056
fatty acid elongation GO:0030497 1 0.056
regulation of nitrogen compound metabolic process GO:0051171 251 0.054
cell death GO:0008219 121 0.054
hemopoiesis GO:0030097 183 0.053
cellular biosynthetic process GO:0044249 286 0.053
Human Yeast Mouse
morphogenesis of an epithelium GO:0002009 333 0.052
sensory organ development GO:0007423 393 0.051
cell motility GO:0048870 244 0.050
regulation of protein complex assembly GO:0043254 3 0.049
organonitrogen compound metabolic process GO:1901564 74 0.049
Human Yeast Mouse
aging GO:0007568 2 0.049
Yeast
modification dependent macromolecule catabolic process GO:0043632 3 0.049
meiotic cell cycle process GO:1903046 3 0.048
protein import GO:0017038 3 0.048
gastrulation GO:0007369 208 0.048
fatty acid elongation unsaturated fatty acid GO:0019368 1 0.048
gtp catabolic process GO:0006184 2 0.048
single organism transport GO:0044765 206 0.047
gene expression GO:0010467 252 0.047
synaptic vesicle transport GO:0048489 1 0.047
positive regulation of transport GO:0051050 2 0.046
apoptotic process GO:0006915 116 0.045
positive regulation of biological process GO:0048518 253 0.045
organonitrogen compound biosynthetic process GO:1901566 47 0.045
Human Yeast Mouse
oxoacid metabolic process GO:0043436 31 0.045
proteasomal protein catabolic process GO:0010498 2 0.045
negative regulation of cellular process GO:0048523 283 0.044
blood vessel morphogenesis GO:0048514 216 0.044
multicellular organism growth GO:0035264 4 0.044
guanosine containing compound metabolic process GO:1901068 4 0.043
cytoskeleton dependent cytokinesis GO:0061640 3 0.043
ubiquitin dependent protein catabolic process GO:0006511 3 0.042
sensory system development GO:0048880 76 0.042
regulation of metabolic process GO:0019222 359 0.041
vasculature development GO:0001944 278 0.041
nucleobase containing compound biosynthetic process GO:0034654 205 0.041
regulation of carbohydrate metabolic process GO:0006109 4 0.040
regulation of primary metabolic process GO:0080090 311 0.040
membrane lipid metabolic process GO:0006643 10 0.039
Human Yeast Mouse
biosynthetic process GO:0009058 294 0.039
Human Yeast Mouse
aromatic compound biosynthetic process GO:0019438 217 0.039
cellular component movement GO:0006928 335 0.038
central nervous system development GO:0007417 387 0.038
regulation of metal ion transport GO:0010959 4 0.038
exocytosis GO:0006887 1 0.038
regulation of multicellular organismal process GO:0051239 277 0.037
nuclear import GO:0051170 3 0.037
carbohydrate metabolic process GO:0005975 12 0.037
angiogenesis GO:0001525 158 0.037
lipid metabolic process GO:0006629 52 0.036
Human Yeast Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.036
cellular response to lipopolysaccharide GO:0071222 3 0.035
synaptic vesicle localization GO:0097479 1 0.035
establishment of localization GO:0051234 244 0.034
regulation of biosynthetic process GO:0009889 250 0.034
urogenital system development GO:0001655 97 0.034
response to biotic stimulus GO:0009607 97 0.034
nucleocytoplasmic transport GO:0006913 4 0.034
gland development GO:0048732 143 0.033
nuclear transport GO:0051169 4 0.033
positive regulation of cellular process GO:0048522 201 0.033
positive regulation of protein complex assembly GO:0031334 2 0.033
regulation of protein polymerization GO:0032271 2 0.033
regulation of protein binding GO:0043393 3 0.033
positive regulation of catabolic process GO:0009896 4 0.033
microtubule organizing center organization GO:0031023 1 0.032
secondary metabolic process GO:0019748 3 0.032
establishment of synaptic vesicle localization GO:0097480 1 0.032
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.031
heterocycle biosynthetic process GO:0018130 215 0.031
regulation of cell differentiation GO:0045595 142 0.030
response to bacterium GO:0009617 58 0.030
cell morphogenesis GO:0000902 289 0.030
immune response GO:0006955 28 0.030
phosphorus metabolic process GO:0006793 109 0.030
fertilization GO:0009566 3 0.030
response to stress GO:0006950 263 0.030
rna metabolic process GO:0016070 219 0.029
single organism nuclear import GO:1902593 3 0.029
embryonic organ development GO:0048568 381 0.029
intracellular signal transduction GO:0035556 85 0.028
negative regulation of protein phosphorylation GO:0001933 4 0.028
renal system development GO:0072001 94 0.028
meiotic nuclear division GO:0007126 4 0.028
camera type eye development GO:0043010 222 0.028
actin polymerization or depolymerization GO:0008154 2 0.028
negative regulation of metabolic process GO:0009892 86 0.028
kidney development GO:0001822 92 0.027
neuron differentiation GO:0030182 353 0.027
lipid biosynthetic process GO:0008610 22 0.027
Human Yeast Mouse
organic acid metabolic process GO:0006082 31 0.027
sensory organ morphogenesis GO:0090596 200 0.027
cellular macromolecule biosynthetic process GO:0034645 224 0.027
protein import into nucleus GO:0006606 3 0.027
rna localization GO:0006403 4 0.027
cellular response to nutrient levels GO:0031669 2 0.027
negative regulation of macromolecule metabolic process GO:0010605 76 0.027
phagocytosis GO:0006909 3 0.026
single organism localization GO:1902578 225 0.026
gtp metabolic process GO:0046039 4 0.026
hepaticobiliary system development GO:0061008 98 0.026
regulation of intracellular protein transport GO:0033157 3 0.026
organophosphate metabolic process GO:0019637 37 0.026
regulation of protein ubiquitination GO:0031396 3 0.026
carbohydrate derivative biosynthetic process GO:1901137 43 0.026
single organism organelle organization GO:1902589 199 0.025
blood vessel development GO:0001568 246 0.025
fatty acid biosynthetic process GO:0006633 4 0.025
regulation of protein transport GO:0051223 3 0.025
brain development GO:0007420 293 0.025
regulation of establishment of protein localization GO:0070201 4 0.024
response to topologically incorrect protein GO:0035966 2 0.024
regulation of reproductive process GO:2000241 4 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
regulation of multicellular organismal development GO:2000026 223 0.024
embryo development ending in birth or egg hatching GO:0009792 271 0.024
regulation of cytoplasmic transport GO:1903649 4 0.023
pole plasm assembly GO:0007315 4 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
death GO:0016265 121 0.023
endosome organization GO:0007032 2 0.023
intracellular mrna localization GO:0008298 1 0.023
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
chordate embryonic development GO:0043009 271 0.023
g protein coupled receptor signaling pathway GO:0007186 74 0.023
phosphate containing compound metabolic process GO:0006796 108 0.022
cellular amine metabolic process GO:0044106 2 0.022
peptidyl serine phosphorylation GO:0018105 1 0.022
membrane invagination GO:0010324 1 0.022
protein localization to nucleus GO:0034504 3 0.022
cellular carbohydrate metabolic process GO:0044262 4 0.022
cellular response to unfolded protein GO:0034620 2 0.022
organelle organization GO:0006996 227 0.021
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
protein metabolic process GO:0019538 183 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.021
regulation of apoptotic process GO:0042981 98 0.020
response to other organism GO:0051707 97 0.020
cell projection organization GO:0030030 284 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.020
cellular protein modification process GO:0006464 100 0.020
positive regulation of cell adhesion GO:0045785 1 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
germ line stem cell maintenance GO:0030718 2 0.020
transcription dna templated GO:0006351 181 0.020
cellular macromolecule metabolic process GO:0044260 391 0.020
response to external biotic stimulus GO:0043207 97 0.020
cell junction maintenance GO:0034331 2 0.020
response to chemical GO:0042221 320 0.020
cell projection morphogenesis GO:0048858 244 0.019
adult behavior GO:0030534 2 0.019
spindle assembly GO:0051225 2 0.019
protein complex localization GO:0031503 1 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
establishment of protein localization to plasma membrane GO:0090002 1 0.019
regulation of binding GO:0051098 3 0.019
amine metabolic process GO:0009308 2 0.019
reproduction GO:0000003 40 0.019
regulation of oocyte development GO:0060281 3 0.019
cellular protein metabolic process GO:0044267 129 0.019
neuron development GO:0048666 262 0.019
regulation of blood pressure GO:0008217 1 0.019
ribose phosphate biosynthetic process GO:0046390 20 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
defense response to bacterium GO:0042742 22 0.019
positive regulation of nucleoside metabolic process GO:0045979 1 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
generation of neurons GO:0048699 385 0.018
cellular component maintenance GO:0043954 3 0.018
cellular component biogenesis GO:0044085 178 0.018
cellular response to external stimulus GO:0071496 2 0.018
peptidyl serine modification GO:0018209 2 0.018
single organism membrane fusion GO:0044801 2 0.018
regulation of cell development GO:0060284 100 0.018
cell part morphogenesis GO:0032990 246 0.017
positive regulation of nucleic acid templated transcription GO:1903508 57 0.017
estrogen metabolic process GO:0008210 2 0.017
regulation of developmental process GO:0050793 247 0.017
single organism carbohydrate metabolic process GO:0044723 12 0.017
nucleic acid metabolic process GO:0090304 244 0.017
er nucleus signaling pathway GO:0006984 2 0.017
cellular transition metal ion homeostasis GO:0046916 3 0.017
regulation of nucleic acid templated transcription GO:1903506 213 0.017
regulation of gene expression GO:0010468 265 0.017
response to xenobiotic stimulus GO:0009410 45 0.017
positive regulation of transcription dna templated GO:0045893 57 0.017
ribonucleotide metabolic process GO:0009259 27 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
erk1 and erk2 cascade GO:0070371 4 0.017
cell surface receptor signaling pathway GO:0007166 325 0.016
skeletal system development GO:0001501 181 0.016
neuron projection morphogenesis GO:0048812 161 0.016
regulation of protein targeting GO:1903533 2 0.016
guanosine containing compound catabolic process GO:1901069 2 0.016
macromolecule modification GO:0043412 111 0.016
axon development GO:0061564 166 0.016
centrosome cycle GO:0007098 1 0.016
regulation of cell shape GO:0008360 1 0.016
positive regulation of cytoskeleton organization GO:0051495 3 0.016
anterior posterior pattern specification GO:0009952 152 0.016
regulation of rna biosynthetic process GO:2001141 213 0.016
cellular component disassembly GO:0022411 1 0.016
ameboidal type cell migration GO:0001667 143 0.016
phosphorylation GO:0016310 69 0.016
female sex differentiation GO:0046660 4 0.016
regulation of tube size GO:0035150 2 0.015
cellular lipid metabolic process GO:0044255 36 0.015
Human Yeast Mouse
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.015
cytoplasm organization GO:0007028 4 0.015
stem cell maintenance GO:0019827 4 0.015
multicellular organism reproduction GO:0032504 35 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
epithelial tube morphogenesis GO:0060562 148 0.015
epithelial cell differentiation GO:0030855 116 0.015
regulation of signal transduction GO:0009966 225 0.015
cell adhesion GO:0007155 40 0.015
dicarboxylic acid metabolic process GO:0043648 1 0.015
regulation of embryonic development GO:0045995 47 0.015
negative regulation of cell death GO:0060548 60 0.015
regulation of macromolecule biosynthetic process GO:0010556 225 0.015
organelle fusion GO:0048284 3 0.015
protein modification process GO:0036211 100 0.015
regulation of cell death GO:0010941 103 0.015
meiotic chromosome segregation GO:0045132 3 0.014
negative regulation of kinase activity GO:0033673 4 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.014
regulation of sodium ion transport GO:0002028 2 0.014
lipid catabolic process GO:0016042 4 0.014
energy reserve metabolic process GO:0006112 2 0.014
negative regulation of biosynthetic process GO:0009890 55 0.014
regulation of wound healing GO:0061041 2 0.014
regulation of nucleotide catabolic process GO:0030811 2 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
transport GO:0006810 220 0.014
response to amine GO:0014075 1 0.014
specification of symmetry GO:0009799 204 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
regulation of programmed cell death GO:0043067 101 0.014
regulation of proteolysis GO:0030162 24 0.014
rna biosynthetic process GO:0032774 181 0.014
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.014
vesicle localization GO:0051648 27 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
actin filament polymerization GO:0030041 2 0.013
mitotic cytokinesis GO:0000281 3 0.013
long chain fatty acid biosynthetic process GO:0042759 1 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
zymogen activation GO:0031638 3 0.013
cell cycle process GO:0022402 53 0.013
regulation of blood vessel size GO:0050880 2 0.013
transmembrane transport GO:0055085 120 0.013
mitochondrial transport GO:0006839 2 0.013
somitogenesis GO:0001756 87 0.013
gastrulation with mouth forming second GO:0001702 44 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.013
negative regulation of innate immune response GO:0045824 2 0.013
establishment of organelle localization GO:0051656 45 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
lateral line system development GO:0048925 76 0.013
multicellular organismal reproductive process GO:0048609 35 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
nucleic acid templated transcription GO:0097659 181 0.013
negative regulation of catabolic process GO:0009895 3 0.013
post embryonic morphogenesis GO:0009886 4 0.013
membrane fusion GO:0061025 2 0.013
regulation of cell communication GO:0010646 232 0.013
nucleoside phosphate metabolic process GO:0006753 28 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
myeloid cell differentiation GO:0030099 86 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
phagocytosis engulfment GO:0006911 1 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.012
regulation of response to stimulus GO:0048583 269 0.012
negative regulation of response to cytokine stimulus GO:0060761 2 0.012
positive regulation of cell cycle GO:0045787 3 0.012
adherens junction organization GO:0034332 4 0.012
neuron projection development GO:0031175 180 0.012
maternal determination of anterior posterior axis embryo GO:0008358 4 0.012
negative regulation of protein localization to nucleus GO:1900181 2 0.012
positive regulation of ras protein signal transduction GO:0046579 1 0.012
nucleoside biosynthetic process GO:0009163 2 0.012
synaptic vesicle endocytosis GO:0048488 1 0.012
leukocyte mediated cytotoxicity GO:0001909 1 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
cellular component morphogenesis GO:0032989 336 0.012
developmental maturation GO:0021700 34 0.012
organic substance transport GO:0071702 58 0.012
regulation of protein catabolic process GO:0042176 1 0.012
hatching GO:0035188 4 0.012
positive regulation of cell division GO:0051781 2 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
organic substance catabolic process GO:1901575 28 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
positive regulation of protein polymerization GO:0032273 2 0.012
detection of abiotic stimulus GO:0009582 24 0.012
multi organism process GO:0051704 134 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
segmentation GO:0035282 97 0.012
synaptic growth at neuromuscular junction GO:0051124 2 0.012
regulation of cytokine production GO:0001817 3 0.012
cell migration involved in gastrulation GO:0042074 79 0.012
system process GO:0003008 185 0.011
regulation of synapse organization GO:0050807 3 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
regulation of cytokine mediated signaling pathway GO:0001959 3 0.011
nucleotide biosynthetic process GO:0009165 21 0.011
cognition GO:0050890 1 0.011
regulation of transcription dna templated GO:0006355 213 0.011
retina development in camera type eye GO:0060041 146 0.011
determination of bilateral symmetry GO:0009855 204 0.011
eye morphogenesis GO:0048592 144 0.011
regulation of cellular metabolic process GO:0031323 320 0.011
endocrine process GO:0050886 2 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
ion transport GO:0006811 114 0.011
regulation of blood coagulation GO:0030193 1 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
negative regulation of reproductive process GO:2000242 3 0.011
somite development GO:0061053 96 0.011
embryonic cranial skeleton morphogenesis GO:0048701 90 0.011
negative regulation of immune response GO:0050777 2 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
steroid hormone mediated signaling pathway GO:0043401 9 0.011
innate immune response GO:0045087 13 0.011
cellular component assembly GO:0022607 170 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
regulation of dendrite morphogenesis GO:0048814 3 0.011
regulation of response to cytokine stimulus GO:0060759 3 0.011
cellular response to hormone stimulus GO:0032870 39 0.011
epiboly GO:0090504 41 0.011
negative regulation of defense response GO:0031348 2 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
catabolic process GO:0009056 32 0.011
cortical actin cytoskeleton organization GO:0030866 1 0.011
regulation of dendrite development GO:0050773 3 0.010
multi organism reproductive process GO:0044703 36 0.010
lymphocyte proliferation GO:0046651 1 0.010
negative regulation of cell communication GO:0010648 96 0.010
chemical homeostasis GO:0048878 49 0.010
regulation of protein localization to plasma membrane GO:1903076 1 0.010
antimicrobial humoral response GO:0019730 2 0.010
embryonic heart tube morphogenesis GO:0003143 108 0.010
regulation of systemic arterial blood pressure GO:0003073 1 0.010
cellular response to starvation GO:0009267 1 0.010
cellular localization GO:0051641 97 0.010
determination of left right symmetry GO:0007368 179 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010

lass5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.053
inherited metabolic disorder DOID:655 0 0.053
disease of anatomical entity DOID:7 0 0.022
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013