Danio rerio

0 known processes

aco1

aconitase 1, soluble

(Aliases: wu:fo75b03)

aco1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heme metabolic process GO:0042168 9 0.772
digestive system process GO:0022600 9 0.554
Mouse
intestinal absorption GO:0050892 2 0.425
Mouse
cellular transition metal ion homeostasis GO:0046916 3 0.296
Mouse
regulation of metabolic process GO:0019222 359 0.260
Mouse
single organism localization GO:1902578 225 0.188
Mouse
single organism transport GO:0044765 206 0.184
Mouse
myeloid leukocyte differentiation GO:0002573 15 0.182
gene expression GO:0010467 252 0.177
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.173
organic substance biosynthetic process GO:1901576 289 0.171
Mouse
cellular biosynthetic process GO:0044249 286 0.169
Mouse
cation homeostasis GO:0055080 33 0.153
Mouse
regulation of biological quality GO:0065008 263 0.147
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.147
Mouse
regulation of biosynthetic process GO:0009889 250 0.146
Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.138
cofactor biosynthetic process GO:0051188 10 0.136
erythrocyte homeostasis GO:0034101 55 0.133
cofactor metabolic process GO:0051186 15 0.132
macromolecule biosynthetic process GO:0009059 227 0.127
Mouse
hemopoiesis GO:0030097 183 0.123
cellular nitrogen compound metabolic process GO:0034641 290 0.115
organonitrogen compound metabolic process GO:1901564 74 0.114
nitrogen compound metabolic process GO:0006807 319 0.111
cellular nitrogen compound biosynthetic process GO:0044271 218 0.111
regulation of gene expression GO:0010468 265 0.109
Mouse
osteoclast differentiation GO:0030316 1 0.109
porphyrin containing compound metabolic process GO:0006778 10 0.105
transition metal ion homeostasis GO:0055076 5 0.103
Mouse
myeloid cell differentiation GO:0030099 86 0.099
endosomal transport GO:0016197 2 0.095
heterocycle metabolic process GO:0046483 290 0.090
protein metabolic process GO:0019538 183 0.090
Mouse
cellular protein metabolic process GO:0044267 129 0.088
Mouse
single organism biosynthetic process GO:0044711 71 0.087
single organism metabolic process GO:0044710 217 0.085
transport GO:0006810 220 0.082
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.081
regulation of cellular metabolic process GO:0031323 320 0.079
Mouse
myeloid cell homeostasis GO:0002262 56 0.079
aromatic compound biosynthetic process GO:0019438 217 0.077
larval development GO:0002164 2 0.076
chemical homeostasis GO:0048878 49 0.072
Mouse
ion homeostasis GO:0050801 41 0.069
Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.066
maintenance of location GO:0051235 4 0.065
cellular macromolecule metabolic process GO:0044260 391 0.065
Mouse
immune system development GO:0002520 191 0.061
heterocycle biosynthetic process GO:0018130 215 0.060
tetrapyrrole metabolic process GO:0033013 10 0.058
cellular iron ion homeostasis GO:0006879 3 0.058
Mouse
response to stress GO:0006950 263 0.057
autophagy GO:0006914 4 0.056
cellular cation homeostasis GO:0030003 17 0.056
Mouse
organonitrogen compound biosynthetic process GO:1901566 47 0.054
establishment of localization GO:0051234 244 0.053
Mouse
porphyrin containing compound biosynthetic process GO:0006779 8 0.052
regulation of signaling GO:0023051 235 0.051
single organism membrane fusion GO:0044801 2 0.051
organelle fusion GO:0048284 3 0.050
immune system process GO:0002376 241 0.049
regulation of nitrogen compound metabolic process GO:0051171 251 0.049
homeostasis of number of cells GO:0048872 62 0.048
regulation of protein metabolic process GO:0051246 56 0.045
Mouse
positive regulation of transport GO:0051050 2 0.045
phagocytosis GO:0006909 3 0.044
cellular amide metabolic process GO:0043603 4 0.043
cellular response to extracellular stimulus GO:0031668 2 0.043
membrane fusion GO:0061025 2 0.043
cellular ion homeostasis GO:0006873 17 0.043
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.042
Mouse
transcription dna templated GO:0006351 181 0.041
regulation of protein complex assembly GO:0043254 3 0.040
leukocyte differentiation GO:0002521 25 0.039
cellular response to external stimulus GO:0071496 2 0.038
establishment of protein localization to organelle GO:0072594 4 0.037
cellular macromolecule biosynthetic process GO:0034645 224 0.037
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.037
response to external stimulus GO:0009605 264 0.036
positive regulation of map kinase activity GO:0043406 3 0.036
cellular chemical homeostasis GO:0055082 17 0.036
Mouse
translation GO:0006412 5 0.035
Mouse
homeostatic process GO:0042592 142 0.035
Mouse
negative regulation of sequestering of calcium ion GO:0051283 4 0.034
regulation of cellular protein metabolic process GO:0032268 52 0.034
Mouse
lipid storage GO:0019915 1 0.033
response to carbohydrate GO:0009743 3 0.033
positive regulation of cellular component biogenesis GO:0044089 3 0.033
aging GO:0007568 2 0.033
cellular homeostasis GO:0019725 26 0.032
Mouse
response to hexose GO:0009746 3 0.032
cellular response to starvation GO:0009267 1 0.031
i kappab kinase nf kappab signaling GO:0007249 4 0.031
regulation of macromolecule metabolic process GO:0060255 317 0.031
Mouse
cellular component movement GO:0006928 335 0.030
regulation of cell communication GO:0010646 232 0.029
carbon dioxide transport GO:0015670 3 0.029
response to chemical GO:0042221 320 0.029
pigment metabolic process GO:0042440 12 0.028
metal ion homeostasis GO:0055065 26 0.028
Mouse
leukocyte proliferation GO:0070661 1 0.028
multicellular organism growth GO:0035264 4 0.027
gas transport GO:0015669 3 0.027
extrinsic apoptotic signaling pathway GO:0097191 3 0.027
embryonic organ development GO:0048568 381 0.027
protein heterooligomerization GO:0051291 1 0.027
digestive tract morphogenesis GO:0048546 231 0.026
ubiquitin dependent protein catabolic process GO:0006511 3 0.026
cellular response to nutrient levels GO:0031669 2 0.026
protein acetylation GO:0006473 2 0.026
response to external biotic stimulus GO:0043207 97 0.026
regulation of translation GO:0006417 3 0.025
Mouse
positive regulation of cytoskeleton organization GO:0051495 3 0.025
signal transduction GO:0007165 455 0.025
sequestering of metal ion GO:0051238 3 0.025
nucleobase containing compound metabolic process GO:0006139 274 0.024
amine metabolic process GO:0009308 2 0.024
cytoskeleton dependent cytokinesis GO:0061640 3 0.024
regulation of nucleic acid templated transcription GO:1903506 213 0.024
stem cell proliferation GO:0072089 4 0.023
posttranscriptional regulation of gene expression GO:0010608 14 0.023
Mouse
protein localization to nucleus GO:0034504 3 0.023
regulation of blood coagulation GO:0030193 1 0.023
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.022
negative regulation of protein phosphorylation GO:0001933 4 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
neurotransmitter transport GO:0006836 2 0.022
phagosome maturation GO:0090382 1 0.022
sleep GO:0030431 1 0.022
sequestering of calcium ion GO:0051208 3 0.022
cellular metal ion homeostasis GO:0006875 16 0.022
Mouse
vasculature development GO:0001944 278 0.022
positive regulation of cellular process GO:0048522 201 0.021
regulation of multicellular organism growth GO:0040014 4 0.021
digestion GO:0007586 11 0.021
Mouse
cellular amine metabolic process GO:0044106 2 0.021
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
cytosolic calcium ion transport GO:0060401 3 0.021
nucleocytoplasmic transport GO:0006913 4 0.020
peptide transport GO:0015833 1 0.020
adult behavior GO:0030534 2 0.020
nucleic acid templated transcription GO:0097659 181 0.020
response to other organism GO:0051707 97 0.020
cellular component morphogenesis GO:0032989 336 0.020
cytokinesis GO:0000910 3 0.020
positive regulation of catabolic process GO:0009896 4 0.020
macroautophagy GO:0016236 1 0.019
meiotic nuclear division GO:0007126 4 0.019
response to monosaccharide GO:0034284 3 0.019
positive regulation of biological process GO:0048518 253 0.019
regulation of response to stimulus GO:0048583 269 0.019
regulation of wound healing GO:0061041 2 0.019
internal peptidyl lysine acetylation GO:0018393 2 0.019
protein polymerization GO:0051258 4 0.019
positive regulation of immune effector process GO:0002699 3 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
neuron neuron synaptic transmission GO:0007270 1 0.018
cell motility GO:0048870 244 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
positive regulation of protein complex assembly GO:0031334 2 0.018
cellular component biogenesis GO:0044085 178 0.018
cellular carbohydrate metabolic process GO:0044262 4 0.018
nuclear transport GO:0051169 4 0.018
regulation of synapse assembly GO:0051963 3 0.018
nucleic acid metabolic process GO:0090304 244 0.018
digestive tract development GO:0048565 265 0.018
rna localization GO:0006403 4 0.018
biosynthetic process GO:0009058 294 0.018
Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.017
multicellular organismal metabolic process GO:0044236 2 0.017
cell projection organization GO:0030030 284 0.017
tissue remodeling GO:0048771 4 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.017
translational initiation GO:0006413 3 0.017
cellular response to biotic stimulus GO:0071216 3 0.017
stem cell maintenance GO:0019827 4 0.017
cellular ketone metabolic process GO:0042180 11 0.017
tube morphogenesis GO:0035239 349 0.017
rna metabolic process GO:0016070 219 0.017
synaptic vesicle localization GO:0097479 1 0.017
release of sequestered calcium ion into cytosol GO:0051209 3 0.017
peptide metabolic process GO:0006518 1 0.017
cell projection morphogenesis GO:0048858 244 0.017
removal of superoxide radicals GO:0019430 2 0.017
response to glucose GO:0009749 3 0.017
response to abiotic stimulus GO:0009628 122 0.017
neuron differentiation GO:0030182 353 0.016
regulation of reactive oxygen species metabolic process GO:2000377 2 0.016
regulation of protein transport GO:0051223 3 0.016
positive regulation of protein polymerization GO:0032273 2 0.016
regulation of sequestering of calcium ion GO:0051282 4 0.016
growth GO:0040007 174 0.016
taxis GO:0042330 109 0.016
neurotransmitter secretion GO:0007269 2 0.016
single organism nuclear import GO:1902593 3 0.016
response to superoxide GO:0000303 2 0.016
positive regulation of myeloid cell differentiation GO:0045639 2 0.016
response to amine GO:0014075 1 0.016
regulation of autophagy GO:0010506 3 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
pigment biosynthetic process GO:0046148 9 0.016
organelle organization GO:0006996 227 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
regulation of cell activation GO:0050865 1 0.015
cellular component disassembly GO:0022411 1 0.015
regulation of organelle assembly GO:1902115 4 0.015
hormone transport GO:0009914 2 0.015
regulation of protein targeting GO:1903533 2 0.015
generation of neurons GO:0048699 385 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
chordate embryonic development GO:0043009 271 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
actin polymerization or depolymerization GO:0008154 2 0.015
response to oxygen radical GO:0000305 2 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
protein import GO:0017038 3 0.015
oxoacid metabolic process GO:0043436 31 0.015
regulation of metal ion transport GO:0010959 4 0.015
negative regulation of signaling GO:0023057 96 0.015
protein targeting to nucleus GO:0044744 3 0.014
macromolecule modification GO:0043412 111 0.014
regulation of coagulation GO:0050818 2 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
regulation of signal transduction GO:0009966 225 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
cell migration GO:0016477 237 0.014
nuclear import GO:0051170 3 0.014
compound eye development GO:0048749 2 0.014
regulation of circadian rhythm GO:0042752 4 0.014
lamellipodium organization GO:0097581 1 0.014
protein import into nucleus GO:0006606 3 0.014
lipid catabolic process GO:0016042 4 0.014
negative regulation of mapk cascade GO:0043409 4 0.014
organic acid metabolic process GO:0006082 31 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.014
phosphorylation GO:0016310 69 0.013
gtp metabolic process GO:0046039 4 0.013
regulation of binding GO:0051098 3 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
cellular response to reactive oxygen species GO:0034614 2 0.013
small molecule catabolic process GO:0044282 3 0.013
nucleic acid transport GO:0050657 2 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
mononuclear cell proliferation GO:0032943 1 0.013
regulation of neurotransmitter transport GO:0051588 1 0.013
negative regulation of biological process GO:0048519 304 0.013
cell part morphogenesis GO:0032990 246 0.013
neuron projection development GO:0031175 180 0.013
detection of chemical stimulus GO:0009593 4 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
regulation of transcription dna templated GO:0006355 213 0.013
protein localization to plasma membrane GO:0072659 1 0.013
axonogenesis GO:0007409 152 0.013
cellular modified amino acid metabolic process GO:0006575 3 0.013
golgi vesicle transport GO:0048193 3 0.013
actin filament polymerization GO:0030041 2 0.013
cell substrate adhesion GO:0031589 4 0.013
female gonad development GO:0008585 4 0.013
membrane invagination GO:0010324 1 0.013
positive regulation of cell cycle GO:0045787 3 0.013
regulation of meiotic cell cycle GO:0051445 1 0.013
regulation of cell projection assembly GO:0060491 4 0.013
response to biotic stimulus GO:0009607 97 0.013
cellular lipid catabolic process GO:0044242 3 0.013
internal protein amino acid acetylation GO:0006475 2 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
regulation of intracellular protein transport GO:0033157 3 0.012
cell killing GO:0001906 2 0.012
negative regulation of signal transduction GO:0009968 94 0.012
regulation of tube size GO:0035150 2 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
response to amphetamine GO:0001975 1 0.012
superoxide metabolic process GO:0006801 2 0.012
protein modification process GO:0036211 100 0.012
rna biosynthetic process GO:0032774 181 0.012
gtp catabolic process GO:0006184 2 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
muscle structure development GO:0061061 196 0.012
exocytosis GO:0006887 1 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
protein complex disassembly GO:0043241 1 0.012
establishment of localization in cell GO:0051649 77 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
response to hydrogen peroxide GO:0042542 3 0.012
axon development GO:0061564 166 0.012
calcium ion transport into cytosol GO:0060402 3 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
chemotaxis GO:0006935 104 0.012
regulation of dendrite development GO:0050773 3 0.012
regulation of reproductive process GO:2000241 4 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
alcohol biosynthetic process GO:0046165 2 0.012
locomotion GO:0040011 313 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
antimicrobial humoral response GO:0019730 2 0.012
regulation of rna metabolic process GO:0051252 224 0.012
response to drug GO:0042493 3 0.012
regulation of protein depolymerization GO:1901879 1 0.012
protein complex localization GO:0031503 1 0.012
neuron projection morphogenesis GO:0048812 161 0.012
negative regulation of cellular process GO:0048523 283 0.012
collagen biosynthetic process GO:0032964 2 0.012
negative regulation of nucleic acid templated transcription GO:1903507 45 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
convergent extension GO:0060026 118 0.011
regulation of cytokine production GO:0001817 3 0.011
regulation of transporter activity GO:0032409 2 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
mitochondrion organization GO:0007005 4 0.011
bone remodeling GO:0046849 2 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.011
cellular protein modification process GO:0006464 100 0.011
negative regulation of kinase activity GO:0033673 4 0.011
cellular component assembly GO:0022607 170 0.011
positive regulation of secretion GO:0051047 1 0.011
regulation of cell shape GO:0008360 1 0.011
protein homooligomerization GO:0051260 3 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
protein secretion GO:0009306 1 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
carbohydrate homeostasis GO:0033500 1 0.011
cell morphogenesis GO:0000902 289 0.011
cytoplasm organization GO:0007028 4 0.011
regulation of jak stat cascade GO:0046425 3 0.011
cation transport GO:0006812 81 0.011
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
type b pancreatic cell development GO:0003323 4 0.011
hormone secretion GO:0046879 2 0.011
negative regulation of map kinase activity GO:0043407 2 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
positive regulation of wound healing GO:0090303 1 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
regulation of organ growth GO:0046620 3 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
stem cell division GO:0017145 1 0.010
endocrine process GO:0050886 2 0.010
mechanosensory behavior GO:0007638 2 0.010
regulation of transport GO:0051049 45 0.010
regulation of developmental process GO:0050793 247 0.010
negative regulation of catabolic process GO:0009895 3 0.010
negative regulation of multi organism process GO:0043901 3 0.010
retina development in camera type eye GO:0060041 146 0.010
somatic muscle development GO:0007525 4 0.010
regulation of erythrocyte differentiation GO:0045646 2 0.010
establishment of rna localization GO:0051236 3 0.010
regulation of dendrite morphogenesis GO:0048814 3 0.010
cortical cytoskeleton organization GO:0030865 1 0.010
cellular localization GO:0051641 97 0.010
single fertilization GO:0007338 3 0.010
macromolecular complex disassembly GO:0032984 1 0.010
positive regulation of cell activation GO:0050867 1 0.010
microtubule organizing center organization GO:0031023 1 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.010
sensory perception of chemical stimulus GO:0007606 3 0.010

aco1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.024
inherited metabolic disorder DOID:655 0 0.022
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.017
disease of cellular proliferation DOID:14566 0 0.013
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
cancer DOID:162 0 0.010
organ system cancer DOID:0050686 0 0.010