Danio rerio

37 known processes

pafah1b1b

platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b

(Aliases: Lis1a)

pafah1b1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
microtubule based movement GO:0007018 33 0.992
Mouse Worm Fly
retrograde axon cargo transport GO:0008090 1 0.967
Mouse Fly
nuclear migration GO:0007097 3 0.936
Rat Worm Fly
pronuclear migration GO:0035046 1 0.927
Worm
regulation of microtubule based movement GO:0060632 3 0.900
Fly
cellular component assembly GO:0022607 170 0.822
Mouse Worm Fly
cytoskeleton dependent intracellular transport GO:0030705 10 0.770
Mouse Fly
microtubule organizing center organization GO:0031023 1 0.755
Human Worm Fly
centrosome localization GO:0051642 1 0.742
Rat Fly
organelle transport along microtubule GO:0072384 1 0.693
Mouse Fly
centrosome organization GO:0051297 1 0.679
Worm Fly
positive regulation of transport GO:0051050 2 0.664
Fly
regulation of cell communication GO:0010646 232 0.617
Mouse Fly
fertilization GO:0009566 3 0.613
Worm
establishment of localization GO:0051234 244 0.594
cell projection morphogenesis GO:0048858 244 0.560
Human Rat Fly
retina homeostasis GO:0001895 12 0.560
neuron neuron synaptic transmission GO:0007270 1 0.529
Worm
spermatid development GO:0007286 2 0.526
Mouse
cell motility GO:0048870 244 0.523
Human Mouse Rat Fly
guanosine containing compound metabolic process GO:1901068 4 0.515
Mouse
reciprocal meiotic recombination GO:0007131 1 0.499
Worm
synaptic vesicle transport GO:0048489 1 0.497
Worm
transmission of nerve impulse GO:0019226 19 0.497
Mouse
organelle organization GO:0006996 227 0.490
Human Mouse Worm Fly
single organism transport GO:0044765 206 0.488
Mouse Worm Fly
positive regulation of biological process GO:0048518 253 0.484
Mouse Rat Fly
regulation of signaling GO:0023051 235 0.477
Mouse Fly
regulation of metabolic process GO:0019222 359 0.465
Mouse Fly
signal transduction GO:0007165 455 0.459
Mouse Fly
organelle fission GO:0048285 23 0.444
Worm
cell surface receptor signaling pathway GO:0007166 325 0.441
Mouse Fly
nucleus organization GO:0006997 7 0.436
Mouse
forebrain cell migration GO:0021885 1 0.436
Mouse
microtubule based transport GO:0010970 10 0.434
Mouse Fly
regulation of gene expression GO:0010468 265 0.423
Fly
single organism localization GO:1902578 225 0.419
Human Mouse Worm Fly
microtubule based process GO:0007017 60 0.418
Human Mouse Worm Fly
regulation of meiotic cell cycle GO:0051445 1 0.418
cell morphogenesis GO:0000902 289 0.417
Human Rat Fly
cell projection organization GO:0030030 284 0.415
Human Rat Fly
regulation of cellular metabolic process GO:0031323 320 0.415
Mouse Fly
negative regulation of response to stimulus GO:0048585 104 0.412
Mouse
positive regulation of neuron apoptotic process GO:0043525 1 0.401
regulation of response to extracellular stimulus GO:0032104 1 0.398
nuclear envelope organization GO:0006998 2 0.398
Mouse
multicellular organism growth GO:0035264 4 0.398
multicellular organismal homeostasis GO:0048871 29 0.397
single organism metabolic process GO:0044710 217 0.388
Mouse Worm
gene expression GO:0010467 252 0.384
Fly
nucleus localization GO:0051647 8 0.380
regulation of intracellular signal transduction GO:1902531 57 0.375
Mouse
reciprocal dna recombination GO:0035825 1 0.374
Worm
cellular catabolic process GO:0044248 27 0.370
Mouse
regulation of nucleotide catabolic process GO:0030811 2 0.369
Mouse
regulation of signal transduction GO:0009966 225 0.369
Mouse Fly
cellular component movement GO:0006928 335 0.345
Human Mouse Rat Worm Fly
brain morphogenesis GO:0048854 18 0.339
biosynthetic process GO:0009058 294 0.336
Fly
larval development GO:0002164 2 0.331
Worm
cognition GO:0050890 1 0.329
Mouse
cellular localization GO:0051641 97 0.325
regulation of cell cycle GO:0051726 52 0.323
Rat Fly
photoreceptor cell maintenance GO:0045494 11 0.321
regulation of multicellular organism growth GO:0040014 4 0.317
transport GO:0006810 220 0.317
Mouse Worm Fly
positive regulation of cell cycle GO:0045787 3 0.315
Rat
adult behavior GO:0030534 2 0.315
Human Mouse
endomembrane system organization GO:0010256 13 0.315
Mouse
stem cell division GO:0017145 1 0.313
Rat
gamete generation GO:0007276 33 0.310
Mouse Fly
locomotion GO:0040011 313 0.310
Human Mouse Rat Worm Fly
heart development GO:0007507 313 0.308
establishment of localization in cell GO:0051649 77 0.308
purine ribonucleotide metabolic process GO:0009150 27 0.303
Mouse
heterocycle metabolic process GO:0046483 290 0.301
Mouse Worm
neurological system process GO:0050877 62 0.300
Human Mouse
neuron projection development GO:0031175 180 0.298
Human Rat Fly
neuroblast proliferation GO:0007405 2 0.298
Mouse Fly
establishment of spindle localization GO:0051293 12 0.297
Human Worm
cellular component disassembly GO:0022411 1 0.295
Mouse
synaptic vesicle localization GO:0097479 1 0.293
Worm
small gtpase mediated signal transduction GO:0007264 8 0.289
regulation of gtp catabolic process GO:0033124 2 0.288
Mouse
central nervous system projection neuron axonogenesis GO:0021952 15 0.286
Human
cellular protein metabolic process GO:0044267 129 0.280
Fly
meiotic nuclear division GO:0007126 4 0.279
Worm
system process GO:0003008 185 0.278
Human Mouse
negative regulation of metabolic process GO:0009892 86 0.274
Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.270
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.269
Mouse Fly
central nervous system development GO:0007417 387 0.263
regulation of establishment of protein localization GO:0070201 4 0.262
nuclear transport GO:0051169 4 0.258
nucleic acid metabolic process GO:0090304 244 0.256
Worm
establishment of synaptic vesicle localization GO:0097480 1 0.251
Worm
nitrogen compound metabolic process GO:0006807 319 0.251
Mouse Worm
rho protein signal transduction GO:0007266 5 0.249
chromosome organization involved in meiosis GO:0070192 1 0.243
Worm
response to stress GO:0006950 263 0.241
Mouse
centrosome cycle GO:0007098 1 0.239
Worm Fly
axon cargo transport GO:0008088 2 0.237
Mouse Fly
regulation of response to nutrient levels GO:0032107 1 0.237
ameboidal type cell migration GO:0001667 143 0.236
Mouse Fly
growth GO:0040007 174 0.232
Rat
stem cell proliferation GO:0072089 4 0.231
Mouse Fly
positive regulation of cellular process GO:0048522 201 0.227
Mouse Rat Fly
small molecule metabolic process GO:0044281 77 0.226
Mouse
protein complex subunit organization GO:0071822 46 0.225
Worm Fly
gtp metabolic process GO:0046039 4 0.225
Mouse
intracellular mrna localization GO:0008298 1 0.222
Fly
cellular pigmentation GO:0033059 30 0.215
negative regulation of cellular process GO:0048523 283 0.213
Mouse Rat Fly
cellular component morphogenesis GO:0032989 336 0.208
Human Mouse Rat Fly
regulation of rho protein signal transduction GO:0035023 2 0.206
Mouse
regulation of protein transport GO:0051223 3 0.206
neuromuscular process controlling balance GO:0050885 3 0.204
Human Mouse
single organism cellular localization GO:1902580 46 0.202
Human Mouse Worm Fly
phagocytosis GO:0006909 3 0.200
Worm
regulation of localization GO:0032879 104 0.199
Fly
cellular aromatic compound metabolic process GO:0006725 295 0.197
Mouse Worm
organelle assembly GO:0070925 110 0.194
Mouse Worm Fly
single organism organelle organization GO:1902589 199 0.194
Human Mouse Worm Fly
cell cycle process GO:0022402 53 0.190
Human Worm Fly
apical protein localization GO:0045176 6 0.188
multicellular organism reproduction GO:0032504 35 0.186
Mouse Fly
anatomical structure homeostasis GO:0060249 36 0.184
regulation of biosynthetic process GO:0009889 250 0.183
Fly
germ cell development GO:0007281 22 0.182
Mouse Fly
autophagy GO:0006914 4 0.182
meiotic cell cycle GO:0051321 5 0.180
Worm
locomotor rhythm GO:0045475 3 0.178
organic cyclic compound metabolic process GO:1901360 301 0.178
Mouse Worm
ribonucleotide metabolic process GO:0009259 27 0.176
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.174
Fly
limbic system development GO:0021761 16 0.172
Mouse
response to chemical GO:0042221 320 0.168
Mouse Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.168
Rat Fly
regulation of primary metabolic process GO:0080090 311 0.166
Mouse Fly
regulation of axon extension GO:0030516 24 0.166
Rat
regulation of reproductive process GO:2000241 4 0.166
regulation of nitrogen compound metabolic process GO:0051171 251 0.165
Mouse Fly
mitotic cell cycle process GO:1903047 48 0.163
Human Worm Fly
protein metabolic process GO:0019538 183 0.161
Fly
macromolecular complex subunit organization GO:0043933 74 0.158
Worm Fly
establishment of vesicle localization GO:0051650 24 0.157
Mouse Worm
synapsis GO:0007129 1 0.157
Worm
aging GO:0007568 2 0.154
cell growth GO:0016049 57 0.153
Rat
intracellular transport GO:0046907 32 0.152
Mouse Fly
vesicle organization GO:0016050 6 0.148
Mouse
catabolic process GO:0009056 32 0.148
Mouse
multicellular organismal signaling GO:0035637 22 0.147
Mouse
digestive tract development GO:0048565 265 0.147
developmental process involved in reproduction GO:0003006 27 0.147
Mouse Fly
neural precursor cell proliferation GO:0061351 20 0.146
Mouse Fly
establishment of organelle localization GO:0051656 45 0.146
spindle assembly GO:0051225 2 0.144
Worm Fly
head development GO:0060322 303 0.142
cellular response to dna damage stimulus GO:0006974 24 0.142
oogenesis GO:0048477 14 0.142
Fly
developmental growth GO:0048589 166 0.141
Rat
response to light stimulus GO:0009416 46 0.139
central nervous system neuron development GO:0021954 29 0.139
Human
cellular component assembly involved in morphogenesis GO:0010927 107 0.138
Mouse Fly
taxis GO:0042330 109 0.137
Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.137
Human Rat Fly
brain development GO:0007420 293 0.136
nucleocytoplasmic transport GO:0006913 4 0.135
central nervous system neuron axonogenesis GO:0021955 18 0.134
Human
heterocycle biosynthetic process GO:0018130 215 0.133
organonitrogen compound metabolic process GO:1901564 74 0.132
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.132
Mouse Fly
phosphorus metabolic process GO:0006793 109 0.131
Mouse
regulation of growth GO:0040008 42 0.130
Rat
regulation of gtpase activity GO:0043087 2 0.130
Mouse
regulation of cellular component organization GO:0051128 86 0.129
Rat Fly
maintenance of location GO:0051235 4 0.128
nucleic acid templated transcription GO:0097659 181 0.128
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.128
Fly
multi organism reproductive process GO:0044703 36 0.127
Mouse Worm Fly
cortical cytoskeleton organization GO:0030865 1 0.127
mitotic cell cycle GO:0000278 64 0.125
Human Rat Worm Fly
pyruvate metabolic process GO:0006090 1 0.125
regulation of cellular component size GO:0032535 30 0.125
Rat
mitotic nuclear division GO:0007067 18 0.124
Worm
regulation of biological quality GO:0065008 263 0.122
nuclear division GO:0000280 23 0.122
Worm
purine nucleotide metabolic process GO:0006163 27 0.121
Mouse
phagocytosis engulfment GO:0006911 1 0.120
Worm
cellular macromolecule biosynthetic process GO:0034645 224 0.120
Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.120
Mouse Worm
sialylation GO:0097503 4 0.119
regulation of protein metabolic process GO:0051246 56 0.117
Fly
regulation of intracellular protein transport GO:0033157 3 0.116
regulation of dna replication GO:0006275 3 0.116
organelle localization GO:0051640 49 0.113
guanosine containing compound catabolic process GO:1901069 2 0.113
Mouse
protein complex biogenesis GO:0070271 30 0.112
Worm Fly
regulation of response to cytokine stimulus GO:0060759 3 0.112
Mouse
regulation of transport GO:0051049 45 0.111
Fly
cell part morphogenesis GO:0032990 246 0.110
Human Rat Fly
response to oxidative stress GO:0006979 11 0.110
response to external stimulus GO:0009605 264 0.110
Fly
chemotaxis GO:0006935 104 0.108
Fly
establishment of protein localization to organelle GO:0072594 4 0.107
response to abiotic stimulus GO:0009628 122 0.106
carbohydrate derivative metabolic process GO:1901135 61 0.106
Mouse
regulation of multicellular organismal process GO:0051239 277 0.106
Rat Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.105
Fly
cellular protein modification process GO:0006464 100 0.105
embryo development ending in birth or egg hatching GO:0009792 271 0.104
Worm
regulation of transcription dna templated GO:0006355 213 0.102
Fly
regulation of molecular function GO:0065009 70 0.100
Mouse
forebrain development GO:0030900 96 0.099
Human Mouse Rat
regulation of cell development GO:0060284 100 0.097
Rat Fly
positive regulation of axon extension GO:0045773 5 0.097
Rat
nucleotide metabolic process GO:0009117 28 0.097
Mouse
peptidyl serine phosphorylation GO:0018105 1 0.096
phosphate containing compound metabolic process GO:0006796 108 0.096
Mouse
behavior GO:0007610 74 0.095
Human Mouse
negative regulation of biological process GO:0048519 304 0.095
Mouse Rat Fly
organic cyclic compound catabolic process GO:1901361 15 0.094
Mouse
protein localization to nucleus GO:0034504 3 0.094
lipid metabolic process GO:0006629 52 0.094
nucleobase containing compound biosynthetic process GO:0034654 205 0.093
amine metabolic process GO:0009308 2 0.092
regulation of response to stress GO:0080134 36 0.090
Mouse
glutamate receptor signaling pathway GO:0007215 1 0.089
homeostatic process GO:0042592 142 0.088
regulation of cellular biosynthetic process GO:0031326 245 0.087
Fly
macromolecule modification GO:0043412 111 0.087
axon extension GO:0048675 45 0.087
Rat
negative regulation of autophagy GO:0010507 1 0.086
digestive tract morphogenesis GO:0048546 231 0.085
regulation of cell morphogenesis GO:0022604 42 0.085
Rat Fly
detection of visible light GO:0009584 12 0.084
regulation of response to stimulus GO:0048583 269 0.084
Mouse Fly
negative regulation of jnk cascade GO:0046329 1 0.083
Mouse
aromatic compound catabolic process GO:0019439 15 0.083
Mouse
positive regulation of cell projection organization GO:0031346 9 0.082
Rat
positive regulation of multicellular organismal process GO:0051240 52 0.082
Rat
neuron development GO:0048666 262 0.082
Human Rat Fly
regulation of oocyte development GO:0060281 3 0.082
regulation of nucleocytoplasmic transport GO:0046822 2 0.082
cell migration GO:0016477 237 0.081
Human Mouse Rat Fly
single organism intracellular transport GO:1902582 25 0.081
Mouse Fly
macromolecule biosynthetic process GO:0009059 227 0.080
Fly
organic substance biosynthetic process GO:1901576 289 0.080
Fly
phosphorylation GO:0016310 69 0.080
Mouse
pole plasm assembly GO:0007315 4 0.078
detection of light stimulus GO:0009583 12 0.078
synaptic growth at neuromuscular junction GO:0051124 2 0.078
macromolecular complex assembly GO:0065003 35 0.078
Worm Fly
cell cycle GO:0007049 93 0.077
Human Rat Worm Fly
multi organism process GO:0051704 134 0.076
Mouse Worm Fly
cell cycle checkpoint GO:0000075 7 0.075
Fly
regulation of cytoplasmic transport GO:1903649 4 0.075
cellular biosynthetic process GO:0044249 286 0.074
Fly
establishment of mitotic spindle orientation GO:0000132 10 0.072
Human Worm
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.072
negative regulation of signaling GO:0023057 96 0.071
Mouse
cellular response to nutrient levels GO:0031669 2 0.071
modification dependent macromolecule catabolic process GO:0043632 3 0.071
translation GO:0006412 5 0.070
Fly
regulation of neurogenesis GO:0050767 87 0.070
Rat Fly
transcription dna templated GO:0006351 181 0.070
rhythmic process GO:0048511 21 0.070
multicellular organismal reproductive process GO:0048609 35 0.069
Mouse Fly
cell division GO:0051301 20 0.068
Rat Fly
cellular component biogenesis GO:0044085 178 0.068
Mouse Worm Fly
localization of cell GO:0051674 244 0.068
Human Mouse Rat Fly
response to dexamethasone GO:0071548 1 0.068
stem cell differentiation GO:0048863 117 0.068
Fly
negative regulation of cellular metabolic process GO:0031324 77 0.067
Mouse
sexual reproduction GO:0019953 36 0.067
Mouse Worm Fly
protein import into nucleus GO:0006606 3 0.067
convergent extension GO:0060026 118 0.066
visual perception GO:0007601 17 0.066
hydrogen peroxide metabolic process GO:0042743 2 0.065
chemosensory behavior GO:0007635 1 0.064
regulation of rna metabolic process GO:0051252 224 0.064
Fly
establishment or maintenance of cell polarity GO:0007163 29 0.063
Human Worm
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.063
protein secretion GO:0009306 1 0.063
Mouse
glucose homeostasis GO:0042593 1 0.062
protein modification process GO:0036211 100 0.062
neuromuscular process GO:0050905 7 0.061
Human Mouse
tube morphogenesis GO:0035239 349 0.061
regulation of cell cycle process GO:0010564 20 0.061
Fly
ribose phosphate metabolic process GO:0019693 27 0.061
Mouse
organic substance catabolic process GO:1901575 28 0.061
Mouse
macromolecular complex disassembly GO:0032984 1 0.060
telencephalon development GO:0021537 14 0.060
Human Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.059
Human Rat Fly
lipid storage GO:0019915 1 0.059
regulation of mitotic cell cycle GO:0007346 25 0.058
Rat Fly
spermatogenesis GO:0007283 7 0.058
Mouse Fly
macromolecule localization GO:0033036 54 0.058
negative regulation of synapse assembly GO:0051964 2 0.057
regulation of autophagy GO:0010506 3 0.057
cilium organization GO:0044782 71 0.057
cell cell signaling GO:0007267 52 0.057
Mouse Worm
regulation of developmental process GO:0050793 247 0.057
Rat Fly
regulation of cell projection organization GO:0031344 44 0.057
Rat Fly
posttranscriptional regulation of gene expression GO:0010608 14 0.057
Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.057
regulation of oxidative stress induced cell death GO:1903201 2 0.056
protein targeting to nucleus GO:0044744 3 0.056
receptor recycling GO:0001881 4 0.056
oocyte development GO:0048599 14 0.056
Fly
negative regulation of cell cycle phase transition GO:1901988 5 0.056
Fly
neuron projection morphogenesis GO:0048812 161 0.055
Human Rat Fly
cell death in response to oxidative stress GO:0036473 2 0.055
positive regulation of axonogenesis GO:0050772 6 0.054
Rat
regulation of synapse assembly GO:0051963 3 0.054
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.054
negative regulation of protein transport GO:0051224 3 0.054
rna localization GO:0006403 4 0.054
Fly
single organism membrane organization GO:0044802 20 0.053
Mouse
regulation of anatomical structure morphogenesis GO:0022603 130 0.053
Rat Fly
negative regulation of cell communication GO:0010648 96 0.052
Mouse
regulation of ras gtpase activity GO:0032318 2 0.052
Mouse
ras protein signal transduction GO:0007265 7 0.052
membrane organization GO:0061024 21 0.052
Mouse Worm
organelle fusion GO:0048284 3 0.051
positive regulation of signaling GO:0023056 56 0.051
Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.051
Fly
positive regulation of neuron projection development GO:0010976 9 0.051
Rat
regulation of cell differentiation GO:0045595 142 0.051
Rat Fly
intracellular signal transduction GO:0035556 85 0.050
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.049
Fly
morphogenesis of an epithelium GO:0002009 333 0.049
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.049
reproduction GO:0000003 40 0.048
Mouse Worm Fly
regulation of bmp signaling pathway GO:0030510 39 0.048
Fly
dopaminergic neuron differentiation GO:0071542 14 0.048
cell migration involved in gastrulation GO:0042074 79 0.048
bmp signaling pathway GO:0030509 52 0.048
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.047
heterocycle catabolic process GO:0046700 15 0.047
Mouse
membrane invagination GO:0010324 1 0.047
Worm
regulation of cellular amine metabolic process GO:0033238 0 0.047
myeloid cell development GO:0061515 32 0.047
Mouse
single organism nuclear import GO:1902593 3 0.047
modulation by virus of host morphology or physiology GO:0019048 1 0.047
pigment granule localization GO:0051875 25 0.046
response to radiation GO:0009314 51 0.046
actin filament based process GO:0030029 64 0.045
Mouse
regulation of purine nucleotide catabolic process GO:0033121 2 0.045
Mouse
melanosome localization GO:0032400 21 0.045
cellular ketone metabolic process GO:0042180 11 0.045
dendrite development GO:0016358 9 0.045
Fly
regulation of phosphorylation GO:0042325 26 0.044
Mouse
gtp catabolic process GO:0006184 2 0.044
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.044
Fly
organic acid metabolic process GO:0006082 31 0.044
protein complex assembly GO:0006461 30 0.044
Worm Fly
negative regulation of phosphate metabolic process GO:0045936 13 0.044
Mouse
regulation of protein catabolic process GO:0042176 1 0.044
regulation of mitotic cell cycle phase transition GO:1901990 8 0.043
Fly
response to osmotic stress GO:0006970 11 0.043
regulation of phospholipase activity GO:0010517 2 0.043
positive regulation of cell adhesion GO:0045785 1 0.042
mitotic cell cycle checkpoint GO:0007093 5 0.042
Fly
cellular protein catabolic process GO:0044257 4 0.042
negative regulation of macromolecule metabolic process GO:0010605 76 0.042
nuclear import GO:0051170 3 0.042
regulation of reactive oxygen species metabolic process GO:2000377 2 0.042
regulation of protein ubiquitination GO:0031396 3 0.041
ribonucleoside metabolic process GO:0009119 11 0.041
Mouse
cellular response to chemical stimulus GO:0070887 157 0.041
Mouse
mitotic spindle organization GO:0007052 5 0.041
Worm
positive regulation of catabolic process GO:0009896 4 0.041
purine containing compound metabolic process GO:0072521 29 0.041
Mouse
regulation of receptor activity GO:0010469 2 0.041
enzyme linked receptor protein signaling pathway GO:0007167 106 0.040
Fly
somatic muscle development GO:0007525 4 0.040
regulation of nervous system development GO:0051960 90 0.039
Rat Fly
determination of heart left right asymmetry GO:0061371 117 0.039
cellular response to stress GO:0033554 62 0.039
Mouse
regulation of cell shape GO:0008360 1 0.039
nucleoside catabolic process GO:0009164 7 0.039
Mouse
generation of neurons GO:0048699 385 0.038
Human Mouse Rat Fly
rhythmic behavior GO:0007622 5 0.038
negative regulation of catabolic process GO:0009895 3 0.038
regulation of synapse organization GO:0050807 3 0.038
purine ribonucleoside triphosphate metabolic process GO:0009205 9 0.038
Mouse
regulation of tube size GO:0035150 2 0.037
regulation of hydrolase activity GO:0051336 28 0.037
Mouse
oocyte anterior posterior axis specification GO:0007314 4 0.037
reproductive process GO:0022414 40 0.037
Mouse Worm Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.037
rna polyadenylation GO:0043631 2 0.037
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.037
muscle structure development GO:0061061 196 0.036
response to hexose GO:0009746 3 0.036
lipid biosynthetic process GO:0008610 22 0.036
regulation of developmental growth GO:0048638 38 0.036
Rat
protein import GO:0017038 3 0.036
negative regulation of protein phosphorylation GO:0001933 4 0.035
circulatory system process GO:0003013 87 0.035
sensory organ morphogenesis GO:0090596 200 0.035
Fly
cellular macromolecule metabolic process GO:0044260 391 0.035
Worm Fly
apoptotic process GO:0006915 116 0.035
glycosyl compound metabolic process GO:1901657 11 0.035
Mouse
regulation of epithelial cell proliferation GO:0050678 3 0.034
positive regulation of secretion by cell GO:1903532 1 0.034
negative regulation of epithelial cell proliferation GO:0050680 1 0.034
muscle cell cellular homeostasis GO:0046716 5 0.034
Fly
nucleobase containing compound metabolic process GO:0006139 274 0.034
Mouse Worm
organophosphate metabolic process GO:0019637 37 0.033
Mouse
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 2 0.033
positive regulation of cell communication GO:0010647 56 0.033
Mouse
cellular nitrogen compound catabolic process GO:0044270 15 0.033
Mouse
establishment of mitotic spindle localization GO:0040001 12 0.033
Human Worm
cellular response to biotic stimulus GO:0071216 3 0.033
axon guidance GO:0007411 86 0.033
Fly
positive regulation of signal transduction GO:0009967 56 0.032
Mouse
regulation of neuron projection development GO:0010975 40 0.032
Rat Fly
regulation of organelle assembly GO:1902115 4 0.032
regulation of binding GO:0051098 3 0.032
sensory perception of chemical stimulus GO:0007606 3 0.032
developmental growth involved in morphogenesis GO:0060560 86 0.032
Rat
carbohydrate homeostasis GO:0033500 1 0.032
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.032
Fly
neuron projection guidance GO:0097485 86 0.031
Fly
renal system development GO:0072001 94 0.031
regulation of phosphate metabolic process GO:0019220 43 0.031
Mouse
purine ribonucleoside metabolic process GO:0046128 10 0.031
Mouse
negative regulation of neurogenesis GO:0050768 20 0.031
Rat
protein n linked glycosylation GO:0006487 1 0.031
osteoclast differentiation GO:0030316 1 0.031
Mouse
cell cycle phase transition GO:0044770 9 0.031
Fly
chordate embryonic development GO:0043009 271 0.031
negative regulation of protein kinase activity GO:0006469 4 0.030
regulation of organelle organization GO:0033043 29 0.030
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.030
positive regulation of cellular component biogenesis GO:0044089 3 0.030
cellular response to extracellular stimulus GO:0031668 2 0.030
mononuclear cell proliferation GO:0032943 1 0.030
single organism behavior GO:0044708 24 0.030
Human Mouse
positive regulation of neuron death GO:1901216 1 0.030
cellular amine metabolic process GO:0044106 2 0.030
response to uv GO:0009411 3 0.030
establishment of cell polarity GO:0030010 18 0.029
Human Worm
regulation of catalytic activity GO:0050790 55 0.029
Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.029
regulation of multicellular organismal development GO:2000026 223 0.029
Rat Fly
protein stabilization GO:0050821 2 0.029
positive regulation of wound healing GO:0090303 1 0.029
cellular homeostasis GO:0019725 26 0.029
Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.029
regulation of rna biosynthetic process GO:2001141 213 0.028
Fly
positive regulation of transcription dna templated GO:0045893 57 0.028
response to monosaccharide GO:0034284 3 0.028
cellular macromolecular complex assembly GO:0034622 24 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.028
cytokinesis GO:0000910 3 0.028
regulation of cellular ketone metabolic process GO:0010565 7 0.028
regulation of protein complex assembly GO:0043254 3 0.028
negative regulation of cell projection organization GO:0031345 9 0.027
Rat
rna biosynthetic process GO:0032774 181 0.027
cellular macromolecule localization GO:0070727 21 0.027
Fly
single organism biosynthetic process GO:0044711 71 0.027
modification dependent protein catabolic process GO:0019941 3 0.027
regulation of stress activated protein kinase signaling cascade GO:0070302 6 0.026
Mouse
positive regulation of cell matrix adhesion GO:0001954 1 0.026
programmed cell death GO:0012501 119 0.026
developmental maturation GO:0021700 34 0.026
Fly
asymmetric protein localization GO:0008105 6 0.026
negative regulation of dna replication GO:0008156 2 0.026
cytoplasm organization GO:0007028 4 0.026
cortical actin cytoskeleton organization GO:0030866 1 0.026
regulation of protein complex disassembly GO:0043244 1 0.026
extrinsic apoptotic signaling pathway GO:0097191 3 0.026
regulation of locomotion GO:0040012 55 0.025
membrane fusion GO:0061025 2 0.025
adherens junction organization GO:0034332 4 0.025
spindle organization GO:0007051 5 0.025
Worm Fly
response to organic substance GO:0010033 153 0.025
Mouse
regulation of nucleotide metabolic process GO:0006140 17 0.025
Mouse
signal transduction by phosphorylation GO:0023014 18 0.025
Mouse
death GO:0016265 121 0.025
embryonic organ morphogenesis GO:0048562 274 0.025
reactive oxygen species biosynthetic process GO:1903409 1 0.025
gastrulation GO:0007369 208 0.025
heart morphogenesis GO:0003007 156 0.025
cellular amino acid metabolic process GO:0006520 7 0.025
negative regulation of cellular catabolic process GO:0031330 3 0.024
carboxylic acid metabolic process GO:0019752 22 0.024
regulation of protein import into nucleus GO:0042306 2 0.024
female gamete generation GO:0007292 14 0.024
Fly
positive regulation of response to stimulus GO:0048584 80 0.024
Mouse

pafah1b1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.376
Human
lissencephaly DOID:0050453 0 0.376
Human
congenital nervous system abnormality DOID:2490 0 0.376
Human
disease of anatomical entity DOID:7 0 0.058
endocrine system disease DOID:28 0 0.058