Danio rerio

0 known processes

sb:eu592

sb:eu592

sb:eu592 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.109
gene expression GO:0010467 252 0.107
aging GO:0007568 2 0.094
larval development GO:0002164 2 0.088
regulation of macromolecule metabolic process GO:0060255 317 0.081
cell part morphogenesis GO:0032990 246 0.080
regulation of signaling GO:0023051 235 0.080
signal transduction GO:0007165 455 0.079
regulation of gene expression GO:0010468 265 0.077
response to chemical GO:0042221 320 0.075
heart development GO:0007507 313 0.073
sensory organ development GO:0007423 393 0.070
cellular component morphogenesis GO:0032989 336 0.067
cellular macromolecule metabolic process GO:0044260 391 0.067
organic substance biosynthetic process GO:1901576 289 0.064
cellular aromatic compound metabolic process GO:0006725 295 0.063
cellular macromolecule biosynthetic process GO:0034645 224 0.063
macromolecule biosynthetic process GO:0009059 227 0.062
positive regulation of biological process GO:0048518 253 0.062
heterocycle metabolic process GO:0046483 290 0.062
positive regulation of transport GO:0051050 2 0.061
cellular component movement GO:0006928 335 0.060
head development GO:0060322 303 0.058
vasculature development GO:0001944 278 0.057
generation of neurons GO:0048699 385 0.057
neuron projection morphogenesis GO:0048812 161 0.057
chordate embryonic development GO:0043009 271 0.057
single organism metabolic process GO:0044710 217 0.052
positive regulation of cellular process GO:0048522 201 0.051
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.051
neuron differentiation GO:0030182 353 0.051
regulation of cellular metabolic process GO:0031323 320 0.050
multicellular organism growth GO:0035264 4 0.049
nitrogen compound metabolic process GO:0006807 319 0.049
blood vessel morphogenesis GO:0048514 216 0.049
organelle organization GO:0006996 227 0.048
blood vessel development GO:0001568 246 0.048
organic cyclic compound metabolic process GO:1901360 301 0.048
regulation of metabolic process GO:0019222 359 0.048
cell substrate adhesion GO:0031589 4 0.048
phagocytosis GO:0006909 3 0.048
cellular component assembly GO:0022607 170 0.047
cell morphogenesis involved in differentiation GO:0000904 195 0.047
regulation of biological quality GO:0065008 263 0.047
cell matrix adhesion GO:0007160 4 0.047
cell morphogenesis GO:0000902 289 0.046
meiotic nuclear division GO:0007126 4 0.046
cognition GO:0050890 1 0.046
nucleobase containing compound biosynthetic process GO:0034654 205 0.045
regulation of cell communication GO:0010646 232 0.044
cellular nitrogen compound metabolic process GO:0034641 290 0.044
regulation of primary metabolic process GO:0080090 311 0.044
cell projection organization GO:0030030 284 0.044
morphogenesis of an epithelium GO:0002009 333 0.043
regulation of protein transport GO:0051223 3 0.043
locomotion GO:0040011 313 0.043
nucleic acid metabolic process GO:0090304 244 0.042
nucleobase containing compound metabolic process GO:0006139 274 0.042
regulation of nitrogen compound metabolic process GO:0051171 251 0.041
cell migration GO:0016477 237 0.041
positive regulation of cellular catabolic process GO:0031331 3 0.041
regulation of developmental process GO:0050793 247 0.040
positive regulation of catabolic process GO:0009896 4 0.040
regulation of cell activation GO:0050865 1 0.040
embryonic organ morphogenesis GO:0048562 274 0.040
localization of cell GO:0051674 244 0.040
tube morphogenesis GO:0035239 349 0.039
biosynthetic process GO:0009058 294 0.039
embryonic organ development GO:0048568 381 0.039
protein metabolic process GO:0019538 183 0.038
cell motility GO:0048870 244 0.038
regionalization GO:0003002 274 0.038
system process GO:0003008 185 0.037
regulation of signal transduction GO:0009966 225 0.037
developmental growth GO:0048589 166 0.037
amine metabolic process GO:0009308 2 0.037
transcription dna templated GO:0006351 181 0.037
regulation of cell development GO:0060284 100 0.037
regulation of macromolecule biosynthetic process GO:0010556 225 0.037
negative regulation of biological process GO:0048519 304 0.036
regulation of establishment of protein localization GO:0070201 4 0.036
brain development GO:0007420 293 0.036
synaptic growth at neuromuscular junction GO:0051124 2 0.035
response to abiotic stimulus GO:0009628 122 0.035
regulation of multicellular organismal process GO:0051239 277 0.035
single organism organelle organization GO:1902589 199 0.035
cell surface receptor signaling pathway GO:0007166 325 0.035
regulation of cytokine production GO:0001817 3 0.034
single organism localization GO:1902578 225 0.034
positive regulation of cellular component biogenesis GO:0044089 3 0.033
response to external stimulus GO:0009605 264 0.033
aromatic compound biosynthetic process GO:0019438 217 0.033
regulation of response to stimulus GO:0048583 269 0.033
regulation of multicellular organism growth GO:0040014 4 0.033
regulation of rna biosynthetic process GO:2001141 213 0.033
digestive system development GO:0055123 289 0.033
cellular component biogenesis GO:0044085 178 0.033
regulation of multicellular organismal development GO:2000026 223 0.032
response to stress GO:0006950 263 0.032
regulation of rna metabolic process GO:0051252 224 0.031
cytoskeleton organization GO:0007010 96 0.031
cell death GO:0008219 121 0.031
organic cyclic compound biosynthetic process GO:1901362 223 0.031
eye development GO:0001654 277 0.031
regulation of biosynthetic process GO:0009889 250 0.031
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.031
regulation of cellular biosynthetic process GO:0031326 245 0.030
axonogenesis GO:0007409 152 0.030
neuron development GO:0048666 262 0.030
embryo development ending in birth or egg hatching GO:0009792 271 0.030
cellular nitrogen compound biosynthetic process GO:0044271 218 0.030
cell projection morphogenesis GO:0048858 244 0.029
regulation of synapse organization GO:0050807 3 0.029
heterocycle biosynthetic process GO:0018130 215 0.029
immune system process GO:0002376 241 0.029
gtp metabolic process GO:0046039 4 0.028
neuron projection development GO:0031175 180 0.028
regulation of cell differentiation GO:0045595 142 0.028
rna metabolic process GO:0016070 219 0.028
regulation of gtp catabolic process GO:0033124 2 0.028
regulation of transcription dna templated GO:0006355 213 0.028
anterior posterior pattern specification GO:0009952 152 0.028
neurological system process GO:0050877 62 0.027
nucleic acid templated transcription GO:0097659 181 0.027
transport GO:0006810 220 0.027
growth GO:0040007 174 0.027
chemotaxis GO:0006935 104 0.027
cellular amine metabolic process GO:0044106 2 0.026
establishment of localization GO:0051234 244 0.026
maintenance of location GO:0051235 4 0.026
cellular protein metabolic process GO:0044267 129 0.026
cellular biosynthetic process GO:0044249 286 0.026
rna biosynthetic process GO:0032774 181 0.026
guanosine containing compound metabolic process GO:1901068 4 0.025
spermatid differentiation GO:0048515 2 0.025
heart morphogenesis GO:0003007 156 0.025
axon guidance GO:0007411 86 0.025
regulation of synapse assembly GO:0051963 3 0.024
positive regulation of cell cycle GO:0045787 3 0.024
axon extension GO:0048675 45 0.024
cellular ketone metabolic process GO:0042180 11 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
cellular response to external stimulus GO:0071496 2 0.024
ear development GO:0043583 127 0.024
transcription from rna polymerase ii promoter GO:0006366 80 0.024
organelle assembly GO:0070925 110 0.024
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.024
macromolecule modification GO:0043412 111 0.023
regulation of apoptotic process GO:0042981 98 0.023
positive regulation of immune effector process GO:0002699 3 0.023
ameboidal type cell migration GO:0001667 143 0.023
negative regulation of metabolic process GO:0009892 86 0.023
gtp catabolic process GO:0006184 2 0.023
cellular component assembly involved in morphogenesis GO:0010927 107 0.023
regulation of nucleotide catabolic process GO:0030811 2 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
leukocyte proliferation GO:0070661 1 0.023
regulation of nucleoside metabolic process GO:0009118 2 0.023
regulation of purine nucleotide catabolic process GO:0033121 2 0.023
regulation of cell substrate adhesion GO:0010810 1 0.022
phagocytosis engulfment GO:0006911 1 0.022
guanosine containing compound catabolic process GO:1901069 2 0.022
cortical cytoskeleton organization GO:0030865 1 0.022
erk1 and erk2 cascade GO:0070371 4 0.022
spermatid development GO:0007286 2 0.022
positive regulation of secretion by cell GO:1903532 1 0.022
positive regulation of map kinase activity GO:0043406 3 0.022
cellular localization GO:0051641 97 0.022
cellular protein modification process GO:0006464 100 0.021
response to carbohydrate GO:0009743 3 0.021
angiogenesis GO:0001525 158 0.021
regulation of protein complex assembly GO:0043254 3 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
nucleocytoplasmic transport GO:0006913 4 0.020
regulation of reproductive process GO:2000241 4 0.020
positive regulation of response to stimulus GO:0048584 80 0.020
stem cell maintenance GO:0019827 4 0.020
actin filament based process GO:0030029 64 0.020
actin cytoskeleton organization GO:0030036 63 0.020
intracellular signal transduction GO:0035556 85 0.020
nuclear transport GO:0051169 4 0.019
positive regulation of cytokine production GO:0001819 2 0.019
ventricular cardiac muscle tissue development GO:0003229 3 0.019
lymphocyte proliferation GO:0046651 1 0.019
cytokinesis GO:0000910 3 0.019
amino acid transport GO:0006865 2 0.019
microtubule based process GO:0007017 60 0.019
mononuclear cell proliferation GO:0032943 1 0.019
protein dephosphorylation GO:0006470 3 0.019
regulation of gtpase activity GO:0043087 2 0.019
organelle localization GO:0051640 49 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
positive regulation of cell activation GO:0050867 1 0.018
positive regulation of secretion GO:0051047 1 0.018
neuron projection extension GO:1990138 45 0.018
response to glucose GO:0009749 3 0.018
specification of symmetry GO:0009799 204 0.018
protein modification process GO:0036211 100 0.018
membrane invagination GO:0010324 1 0.018
small molecule metabolic process GO:0044281 77 0.018
axon development GO:0061564 166 0.017
peptide transport GO:0015833 1 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
macromolecular complex subunit organization GO:0043933 74 0.017
protein acetylation GO:0006473 2 0.017
positive regulation of cellular metabolic process GO:0031325 94 0.017
response to monosaccharide GO:0034284 3 0.017
segmentation GO:0035282 97 0.017
epithelial cell differentiation GO:0030855 116 0.017
death GO:0016265 121 0.017
regulation of stem cell differentiation GO:2000736 4 0.017
digestive tract development GO:0048565 265 0.017
negative regulation of macromolecule metabolic process GO:0010605 76 0.017
stem cell proliferation GO:0072089 4 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
single organism cell adhesion GO:0098602 29 0.016
cell fate commitment GO:0045165 99 0.016
epithelial tube morphogenesis GO:0060562 148 0.016
single organism nuclear import GO:1902593 3 0.016
regulation of erk1 and erk2 cascade GO:0070372 4 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
neurotransmitter transport GO:0006836 2 0.016
hematopoietic or lymphoid organ development GO:0048534 191 0.016
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.016
negative regulation of gene expression GO:0010629 65 0.016
response to hexose GO:0009746 3 0.016
inner ear development GO:0048839 126 0.016
regulation of organelle organization GO:0033043 29 0.016
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.016
regulation of meiotic cell cycle GO:0051445 1 0.015
lipid storage GO:0019915 1 0.015
regulation of protein targeting GO:1903533 2 0.015
homeostatic process GO:0042592 142 0.015
cell cycle GO:0007049 93 0.015
establishment of localization in cell GO:0051649 77 0.015
positive regulation of metabolic process GO:0009893 108 0.015
negative regulation of sequestering of calcium ion GO:0051283 4 0.015
regulation of programmed cell death GO:0043067 101 0.015
protein import into nucleus GO:0006606 3 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
multi organism process GO:0051704 134 0.015
sensory system development GO:0048880 76 0.015
nuclear import GO:0051170 3 0.015
regulation of cellular component organization GO:0051128 86 0.015
convergent extension GO:0060026 118 0.015
response to organic substance GO:0010033 153 0.015
response to external biotic stimulus GO:0043207 97 0.015
regulation of cell cycle GO:0051726 52 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
immune system development GO:0002520 191 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
regulation of neurogenesis GO:0050767 87 0.015
cellular amino acid metabolic process GO:0006520 7 0.014
negative regulation of cellular process GO:0048523 283 0.014
regulation of mrna processing GO:0050684 3 0.014
regulation of cell matrix adhesion GO:0001952 1 0.014
positive regulation of ras protein signal transduction GO:0046579 1 0.014
protein import GO:0017038 3 0.014
skeletal system development GO:0001501 181 0.014
stem cell differentiation GO:0048863 117 0.014
cellular response to growth factor stimulus GO:0071363 39 0.014
taxis GO:0042330 109 0.014
camera type eye morphogenesis GO:0048593 108 0.014
lipid catabolic process GO:0016042 4 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
regulation of calcium ion transport GO:0051924 2 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
positive regulation of cell communication GO:0010647 56 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
cortical actin cytoskeleton organization GO:0030866 1 0.014
embryonic heart tube development GO:0035050 133 0.014
small gtpase mediated signal transduction GO:0007264 8 0.014
regulation of cell death GO:0010941 103 0.014
striated muscle tissue development GO:0014706 110 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
mitochondrion organization GO:0007005 4 0.013
gland development GO:0048732 143 0.013
peptidyl serine modification GO:0018209 2 0.013
determination of left right symmetry GO:0007368 179 0.013
b cell activation GO:0042113 2 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
organic acid metabolic process GO:0006082 31 0.013
protein acylation GO:0043543 3 0.013
regulation of metal ion transport GO:0010959 4 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
negative regulation of kinase activity GO:0033673 4 0.013
regulation of cellular protein metabolic process GO:0032268 52 0.013
regulation of response to biotic stimulus GO:0002831 2 0.013
muscle cell development GO:0055001 115 0.013
neurotransmitter secretion GO:0007269 2 0.013
single organism transport GO:0044765 206 0.013
single fertilization GO:0007338 3 0.013
embryonic skeletal system development GO:0048706 97 0.013
regulation of sequestering of calcium ion GO:0051282 4 0.013
negative regulation of protein phosphorylation GO:0001933 4 0.013
female sex differentiation GO:0046660 4 0.013
striated muscle cell differentiation GO:0051146 129 0.013
eye morphogenesis GO:0048592 144 0.013
sensory organ morphogenesis GO:0090596 200 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
regulation of membrane potential GO:0042391 23 0.013
negative regulation of cytokine production GO:0001818 1 0.012
membrane fusion GO:0061025 2 0.012
somite development GO:0061053 96 0.012
fertilization GO:0009566 3 0.012
calcium ion transport into cytosol GO:0060402 3 0.012
chemosensory behavior GO:0007635 1 0.012
somatic muscle development GO:0007525 4 0.012
mitotic dna damage checkpoint GO:0044773 4 0.012
cellular protein catabolic process GO:0044257 4 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
protein targeting to nucleus GO:0044744 3 0.012
cartilage development GO:0051216 96 0.012
oxoacid metabolic process GO:0043436 31 0.012
developmental growth involved in morphogenesis GO:0060560 86 0.012
neuroblast proliferation GO:0007405 2 0.012
cell proliferation GO:0008283 80 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
determination of bilateral symmetry GO:0009855 204 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
cell growth GO:0016049 57 0.012
muscle cell differentiation GO:0042692 139 0.012
cellular response to nutrient levels GO:0031669 2 0.012
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
regulation of binding GO:0051098 3 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.011
cilium morphogenesis GO:0060271 85 0.011
regulation of rho protein signal transduction GO:0035023 2 0.011
antimicrobial humoral response GO:0019730 2 0.011
regulation of intracellular signal transduction GO:1902531 57 0.011
regulation of neurotransmitter transport GO:0051588 1 0.011
response to biotic stimulus GO:0009607 97 0.011
response to alkaloid GO:0043279 2 0.011
positive regulation of gene expression GO:0010628 71 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
muscle structure development GO:0061061 196 0.011
regulation of mrna splicing via spliceosome GO:0048024 3 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
meiotic cell cycle process GO:1903046 3 0.011
activation of mapk activity GO:0000187 3 0.011
response to drug GO:0042493 3 0.011
negative regulation of signaling GO:0023057 96 0.011
muscle organ development GO:0007517 101 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
mitotic cell cycle GO:0000278 64 0.011
secondary metabolic process GO:0019748 3 0.011
heart process GO:0003015 71 0.011
protein secretion GO:0009306 1 0.011
connective tissue development GO:0061448 99 0.011
stem cell development GO:0048864 82 0.011
ras protein signal transduction GO:0007265 7 0.011
action potential GO:0001508 19 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
phosphorylation GO:0016310 69 0.010
sequestering of metal ion GO:0051238 3 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.010
carboxylic acid metabolic process GO:0019752 22 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
exocytosis GO:0006887 1 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010
cellular response to starvation GO:0009267 1 0.010
regulation of protein metabolic process GO:0051246 56 0.010
embryonic skeletal system morphogenesis GO:0048704 93 0.010
negative regulation of signal transduction GO:0009968 94 0.010
hemopoiesis GO:0030097 183 0.010
regulation of muscle contraction GO:0006937 3 0.010
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
cytosolic calcium ion transport GO:0060401 3 0.010

sb:eu592 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.060
musculoskeletal system disease DOID:17 0 0.013
nervous system disease DOID:863 0 0.013