Danio rerio

0 known processes

ela2

elastase 2

ela2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to xenobiotic stimulus GO:0009410 45 0.411
cellular component movement GO:0006928 335 0.129
meiotic chromosome segregation GO:0045132 3 0.128
aging GO:0007568 2 0.120
response to chemical GO:0042221 320 0.118
purine containing compound biosynthetic process GO:0072522 20 0.098
regulation of biological quality GO:0065008 263 0.095
cognition GO:0050890 1 0.075
complement activation GO:0006956 3 0.074
cell surface receptor signaling pathway GO:0007166 325 0.070
small molecule metabolic process GO:0044281 77 0.070
lipid catabolic process GO:0016042 4 0.066
organonitrogen compound metabolic process GO:1901564 74 0.063
regulation of metal ion transport GO:0010959 4 0.062
blood vessel development GO:0001568 246 0.060
spermatid differentiation GO:0048515 2 0.058
organic cyclic compound metabolic process GO:1901360 301 0.050
localization of cell GO:0051674 244 0.050
protein maturation GO:0051604 12 0.049
positive regulation of muscle organ development GO:0048636 1 0.049
signal transduction GO:0007165 455 0.048
cellular macromolecule metabolic process GO:0044260 391 0.047
determination of ventral identity GO:0048264 21 0.047
response to methanol GO:0033986 4 0.043
proteolysis GO:0006508 38 0.042
synaptic target recognition GO:0008039 1 0.040
meiotic nuclear division GO:0007126 4 0.040
single organism localization GO:1902578 225 0.039
small molecule catabolic process GO:0044282 3 0.039
negative regulation of cellular process GO:0048523 283 0.038
regulation of metabolic process GO:0019222 359 0.037
growth GO:0040007 174 0.037
multicellular organism growth GO:0035264 4 0.036
cell motility GO:0048870 244 0.036
blood vessel morphogenesis GO:0048514 216 0.036
phagocytosis GO:0006909 3 0.036
regulation of response to stimulus GO:0048583 269 0.036
cellular hormone metabolic process GO:0034754 19 0.036
striated muscle cell differentiation GO:0051146 129 0.035
heart development GO:0007507 313 0.035
morphogenesis of an epithelium GO:0002009 333 0.034
regulation of primary metabolic process GO:0080090 311 0.034
aromatic compound biosynthetic process GO:0019438 217 0.034
muscle cell differentiation GO:0042692 139 0.034
cellular response to chemical stimulus GO:0070887 157 0.034
positive regulation of cellular amine metabolic process GO:0033240 0 0.034
organism emergence from protective structure GO:0071684 4 0.033
meiotic cell cycle process GO:1903046 3 0.033
regulation of organ growth GO:0046620 3 0.033
single organism metabolic process GO:0044710 217 0.033
positive regulation of transport GO:0051050 2 0.033
purine nucleoside monophosphate catabolic process GO:0009128 4 0.032
single fertilization GO:0007338 3 0.031
fertilization GO:0009566 3 0.030
cellular ketone metabolic process GO:0042180 11 0.030
establishment of localization GO:0051234 244 0.030
organelle organization GO:0006996 227 0.030
regulation of cell communication GO:0010646 232 0.029
cellular nitrogen compound metabolic process GO:0034641 290 0.029
gtp catabolic process GO:0006184 2 0.029
cellular lipid catabolic process GO:0044242 3 0.029
regulation of nucleoside metabolic process GO:0009118 2 0.028
amine metabolic process GO:0009308 2 0.028
ether metabolic process GO:0018904 1 0.028
hatching GO:0035188 4 0.027
larval development GO:0002164 2 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.027
regulation of multicellular organism growth GO:0040014 4 0.027
cellular component assembly involved in morphogenesis GO:0010927 107 0.026
diterpenoid metabolic process GO:0016101 15 0.026
ribonucleotide metabolic process GO:0009259 27 0.026
protein metabolic process GO:0019538 183 0.026
heterocycle metabolic process GO:0046483 290 0.026
regulation of tube size GO:0035150 2 0.026
regulation of muscle hypertrophy GO:0014743 2 0.026
female meiosis chromosome segregation GO:0016321 1 0.026
response to alkaloid GO:0043279 2 0.026
gtp metabolic process GO:0046039 4 0.026
protein processing GO:0016485 12 0.025
fatty acid catabolic process GO:0009062 1 0.025
activation of mapk activity GO:0000187 3 0.025
regulation of cellular metabolic process GO:0031323 320 0.025
zymogen activation GO:0031638 3 0.025
enzyme linked receptor protein signaling pathway GO:0007167 106 0.025
vasculature development GO:0001944 278 0.025
regulation of blood pressure GO:0008217 1 0.025
lipid oxidation GO:0034440 1 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.025
regulation of signal transduction GO:0009966 225 0.024
cellular protein catabolic process GO:0044257 4 0.024
cellular aromatic compound metabolic process GO:0006725 295 0.023
cellular response to methanol GO:0071405 4 0.023
heart morphogenesis GO:0003007 156 0.023
gene expression GO:0010467 252 0.023
regulation of nucleotide biosynthetic process GO:0030808 15 0.023
response to external stimulus GO:0009605 264 0.023
cell cell recognition GO:0009988 1 0.023
negative regulation of metabolic process GO:0009892 86 0.023
single organism transport GO:0044765 206 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
oocyte maturation GO:0001556 4 0.022
guanosine containing compound metabolic process GO:1901068 4 0.022
ameboidal type cell migration GO:0001667 143 0.022
negative regulation of biological process GO:0048519 304 0.022
organic substance biosynthetic process GO:1901576 289 0.022
female meiotic division GO:0007143 2 0.022
tube morphogenesis GO:0035239 349 0.021
nitrogen compound metabolic process GO:0006807 319 0.021
glucose homeostasis GO:0042593 1 0.021
positive regulation of catabolic process GO:0009896 4 0.021
muscle structure development GO:0061061 196 0.021
cellular component disassembly GO:0022411 1 0.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.021
digestive system development GO:0055123 289 0.020
regulation of gene expression GO:0010468 265 0.020
digestive tract development GO:0048565 265 0.020
negative regulation of cellular metabolic process GO:0031324 77 0.020
lipid homeostasis GO:0055088 3 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.019
epithelial cell development GO:0002064 42 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.019
transport GO:0006810 220 0.019
positive regulation of camp metabolic process GO:0030816 2 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
positive regulation of camp biosynthetic process GO:0030819 2 0.019
regulation of blood vessel size GO:0050880 2 0.019
cellular response to xenobiotic stimulus GO:0071466 35 0.018
generation of neurons GO:0048699 385 0.018
positive regulation of secretion by cell GO:1903532 1 0.018
positive regulation of biological process GO:0048518 253 0.018
striated muscle cell development GO:0055002 108 0.018
negative regulation of macromolecule metabolic process GO:0010605 76 0.018
maintenance of location GO:0051235 4 0.018
regulation of ras gtpase activity GO:0032318 2 0.018
actin filament based process GO:0030029 64 0.017
locomotion GO:0040011 313 0.017
apical junction assembly GO:0043297 1 0.017
positive regulation of gtpase activity GO:0043547 1 0.017
response to cold GO:0009409 4 0.017
carbohydrate derivative biosynthetic process GO:1901137 43 0.017
purine ribonucleoside biosynthetic process GO:0046129 2 0.017
positive regulation of secretion GO:0051047 1 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
regulation of protein catabolic process GO:0042176 1 0.017
regulation of developmental process GO:0050793 247 0.016
positive regulation of map kinase activity GO:0043406 3 0.016
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
response to amphetamine GO:0001975 1 0.016
carbohydrate homeostasis GO:0033500 1 0.016
response to amine GO:0014075 1 0.016
response to carbohydrate GO:0009743 3 0.016
response to monosaccharide GO:0034284 3 0.016
cellular catabolic process GO:0044248 27 0.016
negative regulation of feeding behavior GO:2000252 2 0.016
response to ketone GO:1901654 1 0.016
regulation of phosphate metabolic process GO:0019220 43 0.016
negative regulation of gene expression GO:0010629 65 0.015
regulation of signaling GO:0023051 235 0.015
regulation of reproductive process GO:2000241 4 0.015
multicellular organismal response to stress GO:0033555 2 0.015
single organism organelle organization GO:1902589 199 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
actin filament based movement GO:0030048 1 0.015
mycotoxin metabolic process GO:0043385 1 0.015
regionalization GO:0003002 274 0.015
system process GO:0003008 185 0.015
interspecies interaction between organisms GO:0044419 4 0.015
cellular amine metabolic process GO:0044106 2 0.015
cellular biosynthetic process GO:0044249 286 0.015
gastrulation GO:0007369 208 0.014
negative regulation of dna metabolic process GO:0051053 4 0.014
negative regulation of multicellular organismal process GO:0051241 69 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
nucleic acid templated transcription GO:0097659 181 0.014
cellular response to external stimulus GO:0071496 2 0.014
epithelial cell differentiation GO:0030855 116 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
insulin like growth factor receptor signaling pathway GO:0048009 4 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
regulation of body fluid levels GO:0050878 16 0.014
regulation of cell activation GO:0050865 1 0.014
protein activation cascade GO:0072376 6 0.014
cell migration GO:0016477 237 0.014
muscle cell development GO:0055001 115 0.014
cellular amide metabolic process GO:0043603 4 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
homeostatic process GO:0042592 142 0.013
cytoskeleton organization GO:0007010 96 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
calcium ion import GO:0070509 4 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
positive regulation of cellular process GO:0048522 201 0.013
positive regulation of epithelial cell differentiation GO:0030858 2 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
lipid metabolic process GO:0006629 52 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
response to estrogen GO:0043627 27 0.013
regulation of systemic arterial blood pressure GO:0003073 1 0.013
regulation of heart contraction GO:0008016 32 0.013
negative regulation of reproductive process GO:2000242 3 0.013
acetylcholine catabolic process GO:0006581 1 0.013
cellular response to organic substance GO:0071310 105 0.013
organic cyclic compound biosynthetic process GO:1901362 223 0.013
organelle assembly GO:0070925 110 0.013
response to stress GO:0006950 263 0.013
regulation of catalytic activity GO:0050790 55 0.013
regulation of response to interferon gamma GO:0060330 1 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
multicellular organismal metabolic process GO:0044236 2 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.012
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.012
actin mediated cell contraction GO:0070252 1 0.012
regulation of multicellular organismal process GO:0051239 277 0.012
regulation of binding GO:0051098 3 0.012
positive regulation of response to stimulus GO:0048584 80 0.012
cellular component morphogenesis GO:0032989 336 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
positive regulation of ras gtpase activity GO:0032320 1 0.012
monocarboxylic acid catabolic process GO:0072329 3 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
embryonic hemopoiesis GO:0035162 53 0.012
regulation of vasculature development GO:1901342 33 0.012
meiosis i GO:0007127 1 0.012
medial fin development GO:0033338 16 0.012
protein complex disassembly GO:0043241 1 0.012
monoamine transport GO:0015844 1 0.012
neurotransmitter secretion GO:0007269 2 0.012
dna templated transcription elongation GO:0006354 3 0.012
translational initiation GO:0006413 3 0.012
embryonic organ development GO:0048568 381 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
heterocycle biosynthetic process GO:0018130 215 0.011
positive regulation of epithelial cell migration GO:0010634 2 0.011
auditory receptor cell fate determination GO:0042668 2 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
regulation of transporter activity GO:0032409 2 0.011
carbohydrate derivative metabolic process GO:1901135 61 0.011
regulation of establishment of protein localization GO:0070201 4 0.011
specification of symmetry GO:0009799 204 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
cellular protein metabolic process GO:0044267 129 0.011
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.011
endothelial cell differentiation GO:0045446 20 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
wound healing GO:0042060 90 0.011
response to hexose GO:0009746 3 0.011
synaptic transmission glycinergic GO:0060012 1 0.011
response to organic substance GO:0010033 153 0.011
nucleoside biosynthetic process GO:0009163 2 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
membrane invagination GO:0010324 1 0.011
b cell mediated immunity GO:0019724 3 0.011
regulation of bmp signaling pathway GO:0030510 39 0.011
aflatoxin metabolic process GO:0046222 1 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
positive regulation of dna templated transcription elongation GO:0032786 1 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
macromolecular complex disassembly GO:0032984 1 0.010
mitochondrion organization GO:0007005 4 0.010
cell projection morphogenesis GO:0048858 244 0.010
negative regulation of multi organism process GO:0043901 3 0.010
regulation of protein transport GO:0051223 3 0.010
response to drug GO:0042493 3 0.010
regulation of cell shape GO:0008360 1 0.010
cell projection organization GO:0030030 284 0.010
peptidyl lysine acetylation GO:0018394 2 0.010
neuron differentiation GO:0030182 353 0.010
cell morphogenesis GO:0000902 289 0.010
ribose phosphate metabolic process GO:0019693 27 0.010

ela2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
maturity onset diabetes of the young DOID:0050524 0 0.020
disease of anatomical entity DOID:7 0 0.016