Danio rerio

15 known processes

im:7138942

im:7138942

im:7138942 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.130
signal transduction GO:0007165 455 0.082
immune system process GO:0002376 241 0.066
response to stress GO:0006950 263 0.063
response to external stimulus GO:0009605 264 0.058
regulation of cellular metabolic process GO:0031323 320 0.057
cellular nitrogen compound metabolic process GO:0034641 290 0.054
response to chemical GO:0042221 320 0.052
heterocycle metabolic process GO:0046483 290 0.051
nitrogen compound metabolic process GO:0006807 319 0.051
aging GO:0007568 2 0.049
phagocytosis GO:0006909 3 0.048
positive regulation of transport GO:0051050 2 0.047
cellular response to external stimulus GO:0071496 2 0.046
cellular macromolecule metabolic process GO:0044260 391 0.045
regulation of signal transduction GO:0009966 225 0.042
homeostatic process GO:0042592 142 0.042
rna metabolic process GO:0016070 219 0.042
regulation of signaling GO:0023051 235 0.041
regulation of macromolecule metabolic process GO:0060255 317 0.039
regulation of cytokine production GO:0001817 3 0.039
regulation of metabolic process GO:0019222 359 0.039
cell surface receptor signaling pathway GO:0007166 325 0.039
regulation of response to stimulus GO:0048583 269 0.038
heterocycle biosynthetic process GO:0018130 215 0.038
nucleic acid metabolic process GO:0090304 244 0.038
organic substance biosynthetic process GO:1901576 289 0.038
multicellular organism growth GO:0035264 4 0.037
cellular biosynthetic process GO:0044249 286 0.037
maintenance of location GO:0051235 4 0.037
cellular macromolecule biosynthetic process GO:0034645 224 0.037
regulation of biosynthetic process GO:0009889 250 0.036
organic cyclic compound metabolic process GO:1901360 301 0.036
negative regulation of biological process GO:0048519 304 0.036
regulation of nitrogen compound metabolic process GO:0051171 251 0.035
regulation of primary metabolic process GO:0080090 311 0.035
single organism transport GO:0044765 206 0.035
regulation of cell communication GO:0010646 232 0.035
nucleobase containing compound metabolic process GO:0006139 274 0.034
cellular amine metabolic process GO:0044106 2 0.034
response to organic substance GO:0010033 153 0.034
positive regulation of cytokine production GO:0001819 2 0.033
single organism metabolic process GO:0044710 217 0.033
rna biosynthetic process GO:0032774 181 0.033
positive regulation of cellular process GO:0048522 201 0.033
regulation of macromolecule biosynthetic process GO:0010556 225 0.032
small molecule metabolic process GO:0044281 77 0.032
positive regulation of biological process GO:0048518 253 0.031
regulation of gene expression GO:0010468 265 0.031
amine metabolic process GO:0009308 2 0.031
regulation of cellular biosynthetic process GO:0031326 245 0.031
negative regulation of cellular process GO:0048523 283 0.030
regulation of biological quality GO:0065008 263 0.030
organic cyclic compound biosynthetic process GO:1901362 223 0.030
cellular nitrogen compound biosynthetic process GO:0044271 218 0.030
macromolecule biosynthetic process GO:0009059 227 0.029
regulation of protein complex assembly GO:0043254 3 0.029
autophagy GO:0006914 4 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.029
cellular response to extracellular stimulus GO:0031668 2 0.029
response to other organism GO:0051707 97 0.029
nucleic acid templated transcription GO:0097659 181 0.029
regulation of multicellular organism growth GO:0040014 4 0.028
regulation of establishment of protein localization GO:0070201 4 0.028
gene expression GO:0010467 252 0.028
establishment of localization GO:0051234 244 0.028
regulation of protein transport GO:0051223 3 0.027
cellular response to nutrient levels GO:0031669 2 0.027
regulation of rna metabolic process GO:0051252 224 0.027
ubiquitin dependent protein catabolic process GO:0006511 3 0.027
regulation of inflammatory response GO:0050727 2 0.026
nucleocytoplasmic transport GO:0006913 4 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.026
lipid storage GO:0019915 1 0.026
central nervous system development GO:0007417 387 0.026
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.026
protein secretion GO:0009306 1 0.026
nucleobase containing compound biosynthetic process GO:0034654 205 0.025
modification dependent protein catabolic process GO:0019941 3 0.025
aromatic compound biosynthetic process GO:0019438 217 0.025
cellular component movement GO:0006928 335 0.025
single organism localization GO:1902578 225 0.024
modification dependent macromolecule catabolic process GO:0043632 3 0.024
stem cell proliferation GO:0072089 4 0.024
stem cell maintenance GO:0019827 4 0.024
cellular aromatic compound metabolic process GO:0006725 295 0.024
biosynthetic process GO:0009058 294 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
establishment of protein localization to organelle GO:0072594 4 0.023
regulation of rna biosynthetic process GO:2001141 213 0.023
g protein coupled receptor signaling pathway GO:0007186 74 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
eye development GO:0001654 277 0.023
regulation of transcription dna templated GO:0006355 213 0.023
regulation of nucleic acid templated transcription GO:1903506 213 0.023
carboxylic acid metabolic process GO:0019752 22 0.023
gtp metabolic process GO:0046039 4 0.022
cellular response to chemical stimulus GO:0070887 157 0.022
localization of cell GO:0051674 244 0.022
positive regulation of catabolic process GO:0009896 4 0.022
transcription dna templated GO:0006351 181 0.022
meiotic nuclear division GO:0007126 4 0.022
head development GO:0060322 303 0.022
regulation of developmental process GO:0050793 247 0.022
cellular component morphogenesis GO:0032989 336 0.022
response to bacterium GO:0009617 58 0.022
regulation of cellular ketone metabolic process GO:0010565 7 0.021
multi organism process GO:0051704 134 0.021
oxoacid metabolic process GO:0043436 31 0.021
cellular ketone metabolic process GO:0042180 11 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.021
regulation of cell activation GO:0050865 1 0.021
single organism nuclear import GO:1902593 3 0.021
immune system development GO:0002520 191 0.021
cellular protein catabolic process GO:0044257 4 0.021
response to external biotic stimulus GO:0043207 97 0.021
brain development GO:0007420 293 0.021
response to nutrient GO:0007584 3 0.021
nuclear transport GO:0051169 4 0.020
sensory organ development GO:0007423 393 0.020
muscle structure development GO:0061061 196 0.020
transport GO:0006810 220 0.020
response to drug GO:0042493 3 0.020
cellular response to starvation GO:0009267 1 0.020
negative regulation of protein phosphorylation GO:0001933 4 0.020
organic acid metabolic process GO:0006082 31 0.020
positive regulation of cell cycle GO:0045787 3 0.019
response to abiotic stimulus GO:0009628 122 0.019
response to wounding GO:0009611 116 0.019
intracellular signal transduction GO:0035556 85 0.019
embryonic organ development GO:0048568 381 0.019
g1 s transition of mitotic cell cycle GO:0000082 1 0.019
nuclear import GO:0051170 3 0.019
cellular respiration GO:0045333 3 0.019
response to biotic stimulus GO:0009607 97 0.019
organelle fusion GO:0048284 3 0.019
regulation of protein catabolic process GO:0042176 1 0.019
regulation of protein ubiquitination GO:0031396 3 0.019
hemopoiesis GO:0030097 183 0.019
organonitrogen compound metabolic process GO:1901564 74 0.019
cellular response to organic substance GO:0071310 105 0.019
regulation of binding GO:0051098 3 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
vasculature development GO:0001944 278 0.018
i kappab kinase nf kappab signaling GO:0007249 4 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.018
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.018
programmed cell death GO:0012501 119 0.018
blood vessel development GO:0001568 246 0.018
regulation of multicellular organismal development GO:2000026 223 0.018
leukocyte proliferation GO:0070661 1 0.018
generation of neurons GO:0048699 385 0.018
cell motility GO:0048870 244 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
protein import GO:0017038 3 0.018
stem cell division GO:0017145 1 0.018
defense response GO:0006952 47 0.018
positive regulation of cell activation GO:0050867 1 0.018
cellular component disassembly GO:0022411 1 0.018
mitochondrion organization GO:0007005 4 0.017
cellular component assembly GO:0022607 170 0.017
cell projection organization GO:0030030 284 0.017
cellular carbohydrate metabolic process GO:0044262 4 0.017
hematopoietic or lymphoid organ development GO:0048534 191 0.017
protein localization to nucleus GO:0034504 3 0.017
gtp catabolic process GO:0006184 2 0.017
regulation of autophagy GO:0010506 3 0.017
organelle organization GO:0006996 227 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
positive regulation of inflammatory response GO:0050729 1 0.016
protein targeting to nucleus GO:0044744 3 0.016
morphogenesis of an epithelium GO:0002009 333 0.016
response to topologically incorrect protein GO:0035966 2 0.016
negative regulation of secretion by cell GO:1903531 2 0.016
cell morphogenesis GO:0000902 289 0.016
gastrulation GO:0007369 208 0.016
phagocytosis engulfment GO:0006911 1 0.016
membrane fusion GO:0061025 2 0.016
tube morphogenesis GO:0035239 349 0.016
response to endogenous stimulus GO:0009719 83 0.016
apoptotic process GO:0006915 116 0.016
protein import into nucleus GO:0006606 3 0.016
neuron differentiation GO:0030182 353 0.016
sensory organ morphogenesis GO:0090596 200 0.016
embryonic organ morphogenesis GO:0048562 274 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.015
response to glucocorticoid GO:0051384 1 0.015
cellular component biogenesis GO:0044085 178 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
growth GO:0040007 174 0.015
locomotion GO:0040011 313 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
cell death GO:0008219 121 0.015
determination of bilateral symmetry GO:0009855 204 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
regulation of response to nutrient levels GO:0032107 1 0.015
mononuclear cell proliferation GO:0032943 1 0.015
positive regulation of secretion GO:0051047 1 0.015
synaptic growth at neuromuscular junction GO:0051124 2 0.015
macroautophagy GO:0016236 1 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
regulation of circadian rhythm GO:0042752 4 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
negative regulation of catabolic process GO:0009895 3 0.014
response to monosaccharide GO:0034284 3 0.014
cellular response to biotic stimulus GO:0071216 3 0.014
negative regulation of defense response GO:0031348 2 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
cell migration GO:0016477 237 0.014
cell part morphogenesis GO:0032990 246 0.014
angiogenesis GO:0001525 158 0.014
endosomal transport GO:0016197 2 0.014
digestive tract morphogenesis GO:0048546 231 0.014
regulation of localization GO:0032879 104 0.014
cellular response to radiation GO:0071478 4 0.014
macromolecule modification GO:0043412 111 0.014
system process GO:0003008 185 0.014
regulation of metal ion transport GO:0010959 4 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
single organism membrane fusion GO:0044801 2 0.014
cellular response to topologically incorrect protein GO:0035967 2 0.014
membrane invagination GO:0010324 1 0.014
response to lipid GO:0033993 60 0.014
regulation of reproductive process GO:2000241 4 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
atp catabolic process GO:0006200 4 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
response to uv GO:0009411 3 0.013
meiotic cell cycle process GO:1903046 3 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
cell proliferation GO:0008283 80 0.013
cytokinesis GO:0000910 3 0.013
response to hexose GO:0009746 3 0.013
negative regulation of cytokine production GO:0001818 1 0.013
regulation of muscle contraction GO:0006937 3 0.013
death GO:0016265 121 0.013
protein metabolic process GO:0019538 183 0.013
muscle cell differentiation GO:0042692 139 0.013
cellular amide metabolic process GO:0043603 4 0.013
spermatid differentiation GO:0048515 2 0.013
spermatid development GO:0007286 2 0.013
specification of symmetry GO:0009799 204 0.013
regulation of gtpase activity GO:0043087 2 0.013
protein acetylation GO:0006473 2 0.013
response to corticosteroid GO:0031960 1 0.013
positive regulation of map kinase activity GO:0043406 3 0.013
response to glucose GO:0009749 3 0.013
regulation of synaptic plasticity GO:0048167 1 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
positive regulation of stress activated mapk cascade GO:0032874 3 0.013
regulation of reactive oxygen species metabolic process GO:2000377 2 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
protein polyubiquitination GO:0000209 4 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
neurological system process GO:0050877 62 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
neuron development GO:0048666 262 0.012
carbohydrate homeostasis GO:0033500 1 0.012
germ line stem cell maintenance GO:0030718 2 0.012
striated muscle cell differentiation GO:0051146 129 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
blood vessel morphogenesis GO:0048514 216 0.012
digestive system development GO:0055123 289 0.012
determination of left right symmetry GO:0007368 179 0.012
cellular protein metabolic process GO:0044267 129 0.012
hormone secretion GO:0046879 2 0.012
regulation of cell death GO:0010941 103 0.012
positive regulation of cellular component biogenesis GO:0044089 3 0.012
response to carbohydrate GO:0009743 3 0.012
negative regulation of metabolic process GO:0009892 86 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
endoplasmic reticulum unfolded protein response GO:0030968 2 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
heart morphogenesis GO:0003007 156 0.012
secondary metabolic process GO:0019748 3 0.012
lymphocyte proliferation GO:0046651 1 0.012
phosphorylation GO:0016310 69 0.012
positive regulation of response to stimulus GO:0048584 80 0.012
protein modification process GO:0036211 100 0.012
protein stabilization GO:0050821 2 0.012
somatic muscle development GO:0007525 4 0.012
positive regulation of metabolic process GO:0009893 108 0.012
ion transport GO:0006811 114 0.012
heart development GO:0007507 313 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
neuron projection development GO:0031175 180 0.012
neuron neuron synaptic transmission GO:0007270 1 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
neuroblast proliferation GO:0007405 2 0.011
regulation of cellular component organization GO:0051128 86 0.011
cell projection morphogenesis GO:0048858 244 0.011
inner ear development GO:0048839 126 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
cellular protein modification process GO:0006464 100 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
b cell activation GO:0042113 2 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
glucose homeostasis GO:0042593 1 0.011
macromolecular complex disassembly GO:0032984 1 0.011
peptidyl serine modification GO:0018209 2 0.011
regulation of apoptotic process GO:0042981 98 0.011
interspecies interaction between organisms GO:0044419 4 0.011
adult behavior GO:0030534 2 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
chordate embryonic development GO:0043009 271 0.011
female sex differentiation GO:0046660 4 0.011
regulation of dna replication GO:0006275 3 0.011
cognition GO:0050890 1 0.011
rna localization GO:0006403 4 0.011
cellular response to lipid GO:0071396 39 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
compound eye development GO:0048749 2 0.011
regulation of cell shape GO:0008360 1 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
regulation of protein targeting GO:1903533 2 0.010
regulation of nucleocytoplasmic transport GO:0046822 2 0.010
regulation of protein import into nucleus GO:0042306 2 0.010
regulation of synapse assembly GO:0051963 3 0.010
viral process GO:0016032 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
developmental growth GO:0048589 166 0.010
response to alkaloid GO:0043279 2 0.010
protein acylation GO:0043543 3 0.010
positive regulation of signal transduction GO:0009967 56 0.010
regulation of programmed cell death GO:0043067 101 0.010
regulation of tube size GO:0035150 2 0.010
camera type eye development GO:0043010 222 0.010
ear development GO:0043583 127 0.010
regulation of jak stat cascade GO:0046425 3 0.010
regulation of response to cytokine stimulus GO:0060759 3 0.010
cellular response to stress GO:0033554 62 0.010
production of molecular mediator of immune response GO:0002440 2 0.010
regulation of nucleoside metabolic process GO:0009118 2 0.010
regulation of synapse organization GO:0050807 3 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
negative regulation of kinase activity GO:0033673 4 0.010
protein homooligomerization GO:0051260 3 0.010
muscle cell development GO:0055001 115 0.010
positive regulation of protein kinase b signaling GO:0051897 1 0.010
cell morphogenesis involved in differentiation GO:0000904 195 0.010
cell matrix adhesion GO:0007160 4 0.010
response to unfolded protein GO:0006986 2 0.010
axon development GO:0061564 166 0.010
regulation of ras gtpase activity GO:0032318 2 0.010
protein localization to plasma membrane GO:0072659 1 0.010
heart process GO:0003015 71 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.010

im:7138942 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.022
disease of metabolism DOID:0014667 0 0.013
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
inherited metabolic disorder DOID:655 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012