Danio rerio

0 known processes

nlgn3a

neuroligin 3a

(Aliases: nlgn3b)

nlgn3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron neuron synaptic transmission GO:0007270 1 0.833
Mouse
single organism transport GO:0044765 206 0.595
Mouse
ion transmembrane transport GO:0034220 91 0.574
Mouse
transmembrane transport GO:0055085 120 0.438
Mouse
regulation of postsynaptic membrane potential GO:0060078 1 0.387
Mouse
glutamate receptor signaling pathway GO:0007215 1 0.347
Mouse
establishment of localization GO:0051234 244 0.337
Mouse
cognition GO:0050890 1 0.300
Human Mouse
larval development GO:0002164 2 0.261
cell surface receptor signaling pathway GO:0007166 325 0.228
Mouse
positive regulation of biological process GO:0048518 253 0.214
Mouse
adult behavior GO:0030534 2 0.162
Human Fly
regulation of synapse organization GO:0050807 3 0.143
Mouse Fly
neuron differentiation GO:0030182 353 0.135
Mouse
positive regulation of cell communication GO:0010647 56 0.134
Mouse
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 1 0.130
Mouse
regulation of synaptic plasticity GO:0048167 1 0.124
Mouse
neuron projection development GO:0031175 180 0.119
Mouse
regulation of glutamate receptor signaling pathway GO:1900449 1 0.118
Mouse
regulation of receptor activity GO:0010469 2 0.118
Mouse
neurological system process GO:0050877 62 0.112
Human Mouse
regulation of dendrite development GO:0050773 3 0.108
Mouse
single organism localization GO:1902578 225 0.108
Mouse
transport GO:0006810 220 0.103
Mouse
negative regulation of biological process GO:0048519 304 0.100
response to abiotic stimulus GO:0009628 122 0.099
Mouse
cellular component maintenance GO:0043954 3 0.098
Fly
regulation of neuron differentiation GO:0045664 56 0.089
Mouse
single organism metabolic process GO:0044710 217 0.089
neuron projection morphogenesis GO:0048812 161 0.082
Mouse
cell projection organization GO:0030030 284 0.081
Mouse
central nervous system development GO:0007417 387 0.080
Mouse
cation transmembrane transport GO:0098655 65 0.077
signal transduction GO:0007165 455 0.072
Mouse
response to external stimulus GO:0009605 264 0.061
organic substance biosynthetic process GO:1901576 289 0.059
regulation of localization GO:0032879 104 0.058
Mouse
regulation of developmental process GO:0050793 247 0.058
Mouse
stem cell maintenance GO:0019827 4 0.057
regulation of biological quality GO:0065008 263 0.057
Mouse Fly
intracellular signal transduction GO:0035556 85 0.055
cellular macromolecule metabolic process GO:0044260 391 0.055
response to organic substance GO:0010033 153 0.054
response to amino acid GO:0043200 2 0.053
regulation of signaling GO:0023051 235 0.052
Mouse
response to alkaloid GO:0043279 2 0.052
negative regulation of multicellular organismal process GO:0051241 69 0.052
response to food GO:0032094 1 0.052
postsynaptic membrane organization GO:0001941 3 0.050
Mouse
response to stress GO:0006950 263 0.049
cell morphogenesis involved in differentiation GO:0000904 195 0.048
Mouse
negative regulation of secretion by cell GO:1903531 2 0.047
anatomical structure arrangement GO:0048532 2 0.045
ion transport GO:0006811 114 0.044
Mouse
death GO:0016265 121 0.044
synaptic transmission cholinergic GO:0007271 4 0.043
hormone transport GO:0009914 2 0.043
regulation of cell communication GO:0010646 232 0.043
Mouse
programmed cell death GO:0012501 119 0.042
multicellular organism growth GO:0035264 4 0.042
mechanosensory behavior GO:0007638 2 0.042
cellular component morphogenesis GO:0032989 336 0.041
Mouse
generation of neurons GO:0048699 385 0.040
Mouse
neuron development GO:0048666 262 0.040
Mouse
regulation of locomotion GO:0040012 55 0.039
positive regulation of cellular process GO:0048522 201 0.039
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.039
Mouse
actomyosin structure organization GO:0031032 53 0.039
organic substance transport GO:0071702 58 0.039
regulation of reproductive process GO:2000241 4 0.036
regulation of synaptic transmission GO:0050804 4 0.036
Mouse
synaptic transmission GO:0007268 35 0.036
Mouse Fly
negative regulation of protein phosphorylation GO:0001933 4 0.035
regulation of cell projection organization GO:0031344 44 0.035
Mouse
neurotransmitter transport GO:0006836 2 0.034
locomotion GO:0040011 313 0.034
modification dependent protein catabolic process GO:0019941 3 0.033
cellular aromatic compound metabolic process GO:0006725 295 0.033
maintenance of location GO:0051235 4 0.033
cell motility GO:0048870 244 0.033
gene expression GO:0010467 252 0.032
aging GO:0007568 2 0.032
cell death GO:0008219 121 0.032
developmental growth GO:0048589 166 0.032
Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.032
nitrogen compound metabolic process GO:0006807 319 0.031
positive regulation of neuron death GO:1901216 1 0.030
negative regulation of catabolic process GO:0009895 3 0.030
synaptic growth at neuromuscular junction GO:0051124 2 0.030
Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.030
negative chemotaxis GO:0050919 1 0.030
negative regulation of secretion GO:0051048 2 0.029
regulation of response to stimulus GO:0048583 269 0.029
Mouse
negative regulation of gliogenesis GO:0014014 1 0.029
cellular protein catabolic process GO:0044257 4 0.028
synaptic vesicle transport GO:0048489 1 0.028
organonitrogen compound metabolic process GO:1901564 74 0.028
response to light stimulus GO:0009416 46 0.028
Mouse
dendrite development GO:0016358 9 0.028
Mouse
taxis GO:0042330 109 0.028
response to mechanical stimulus GO:0009612 24 0.028
response to drug GO:0042493 3 0.027
oxidation reduction process GO:0055114 41 0.027
locomotory behavior GO:0007626 34 0.027
Fly
positive regulation of transport GO:0051050 2 0.027
Mouse
regulation of nucleotide catabolic process GO:0030811 2 0.027
skeletal system development GO:0001501 181 0.027
sensory perception of chemical stimulus GO:0007606 3 0.026
nucleocytoplasmic transport GO:0006913 4 0.026
response to chemical GO:0042221 320 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.026
glial cell differentiation GO:0010001 42 0.025
Mouse
cation transport GO:0006812 81 0.025
smooth muscle contraction GO:0006939 2 0.025
response to organic cyclic compound GO:0014070 51 0.025
regulation of cellular metabolic process GO:0031323 320 0.025
response to amine GO:0014075 1 0.024
astrocyte differentiation GO:0048708 1 0.024
growth GO:0040007 174 0.024
Fly
guanosine containing compound metabolic process GO:1901068 4 0.024
regulation of metal ion transport GO:0010959 4 0.024
hormone secretion GO:0046879 2 0.024
regulation of establishment of protein localization GO:0070201 4 0.024
ubiquitin dependent protein catabolic process GO:0006511 3 0.023
enzyme linked receptor protein signaling pathway GO:0007167 106 0.023
response to nitrogen compound GO:1901698 19 0.023
response to amphetamine GO:0001975 1 0.023
organelle fusion GO:0048284 3 0.023
negative regulation of cell death GO:0060548 60 0.022
regulation of nucleocytoplasmic transport GO:0046822 2 0.022
regulation of multicellular organism growth GO:0040014 4 0.022
cellular response to external stimulus GO:0071496 2 0.022
multi organism process GO:0051704 134 0.022
Human Mouse Fly
small molecule metabolic process GO:0044281 77 0.022
regulation of cytokine production GO:0001817 3 0.022
response to carbohydrate GO:0009743 3 0.022
regulation of nucleoside metabolic process GO:0009118 2 0.022
regulation of neuronal synaptic plasticity GO:0048168 1 0.022
regulation of multicellular organismal development GO:2000026 223 0.022
Mouse
cellular response to estrogen stimulus GO:0071391 24 0.021
embryonic organ development GO:0048568 381 0.021
cellular lipid catabolic process GO:0044242 3 0.021
cellular response to starvation GO:0009267 1 0.021
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
regulation of intracellular protein transport GO:0033157 3 0.021
cell cell signaling GO:0007267 52 0.021
Mouse Fly
regulation of protein complex assembly GO:0043254 3 0.021
single organism membrane fusion GO:0044801 2 0.021
establishment of synaptic vesicle localization GO:0097480 1 0.021
digestive tract development GO:0048565 265 0.021
nuclear export GO:0051168 1 0.021
behavior GO:0007610 74 0.020
Human Mouse Fly
inorganic ion transmembrane transport GO:0098660 57 0.020
regulation of cell shape GO:0008360 1 0.020
inorganic cation transmembrane transport GO:0098662 50 0.020
cellular response to steroid hormone stimulus GO:0071383 31 0.020
regulation of dendrite morphogenesis GO:0048814 3 0.020
Mouse
mitotic dna damage checkpoint GO:0044773 4 0.020
regulation of synapse assembly GO:0051963 3 0.020
negative regulation of protein transport GO:0051224 3 0.020
negative regulation of protein kinase activity GO:0006469 4 0.020
membrane organization GO:0061024 21 0.019
Mouse Fly
response to steroid hormone GO:0048545 35 0.019
regulation of synapse structure and activity GO:0050803 5 0.019
Mouse Fly
regulation of protein catabolic process GO:0042176 1 0.019
phagocytosis GO:0006909 3 0.019
negative regulation of reproductive process GO:2000242 3 0.019
regulation of protein transport GO:0051223 3 0.019
cellular component assembly GO:0022607 170 0.018
Mouse Fly
post embryonic morphogenesis GO:0009886 4 0.018
regulation of glial cell differentiation GO:0045685 4 0.018
circadian sleep wake cycle sleep GO:0050802 1 0.018
regulation of circadian rhythm GO:0042752 4 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.018
ameboidal type cell migration GO:0001667 143 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
negative regulation of kinase activity GO:0033673 4 0.017
branching morphogenesis of a nerve GO:0048755 4 0.017
regulation of cell morphogenesis GO:0022604 42 0.017
Mouse
apoptotic process GO:0006915 116 0.017
regulation of neural precursor cell proliferation GO:2000177 3 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
cell projection morphogenesis GO:0048858 244 0.017
Mouse
neuromuscular process controlling balance GO:0050885 3 0.017
cell substrate adhesion GO:0031589 4 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
membrane fusion GO:0061025 2 0.016
regulation of anatomical structure morphogenesis GO:0022603 130 0.016
Mouse
regulation of transporter activity GO:0032409 2 0.016
Mouse
circadian sleep wake cycle GO:0042745 2 0.016
oxoacid metabolic process GO:0043436 31 0.016
regulation of neurogenesis GO:0050767 87 0.016
Mouse
autophagy GO:0006914 4 0.016
lipid catabolic process GO:0016042 4 0.016
sodium ion import GO:0097369 3 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
response to hormone GO:0009725 48 0.015
positive regulation of inflammatory response GO:0050729 1 0.015
developmental cell growth GO:0048588 52 0.015
regulation of cytokine mediated signaling pathway GO:0001959 3 0.015
tube morphogenesis GO:0035239 349 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
cellular response to nutrient levels GO:0031669 2 0.014
organelle organization GO:0006996 227 0.014
regulation of circadian sleep wake cycle GO:0042749 1 0.014
cellular component assembly involved in morphogenesis GO:0010927 107 0.014
positive regulation of neuron apoptotic process GO:0043525 1 0.014
cell migration GO:0016477 237 0.014
carbohydrate homeostasis GO:0033500 1 0.014
protein modification process GO:0036211 100 0.014
system process GO:0003008 185 0.014
Human Mouse
embryonic skeletal joint development GO:0072498 3 0.014
positive regulation of cell cycle GO:0045787 3 0.014
negative regulation of cellular process GO:0048523 283 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
camera type eye development GO:0043010 222 0.014
blood vessel development GO:0001568 246 0.014
regulation of calcium ion transport GO:0051924 2 0.014
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
regulation of gtpase activity GO:0043087 2 0.013
regulation of transport GO:0051049 45 0.013
Mouse
monoamine transport GO:0015844 1 0.013
positive regulation of locomotion GO:0040017 14 0.013
sleep GO:0030431 1 0.013
dopamine metabolic process GO:0042417 2 0.013
response to monosaccharide GO:0034284 3 0.013
regulation of apoptotic process GO:0042981 98 0.013
organic acid metabolic process GO:0006082 31 0.013
cell matrix adhesion GO:0007160 4 0.013
myofibril assembly GO:0030239 48 0.013
negative regulation of cellular metabolic process GO:0031324 77 0.013
cellular ketone metabolic process GO:0042180 11 0.013
regulation of ph GO:0006885 3 0.013
heterocycle biosynthetic process GO:0018130 215 0.013
regulation of tube size GO:0035150 2 0.013
post embryonic organ morphogenesis GO:0048563 1 0.013
regulation of primary metabolic process GO:0080090 311 0.013
monovalent inorganic cation transport GO:0015672 42 0.013
catechol containing compound biosynthetic process GO:0009713 2 0.013
response to wounding GO:0009611 116 0.013
regulation of ion transmembrane transport GO:0034765 18 0.012
Mouse
regulation of programmed cell death GO:0043067 101 0.012
catechol containing compound metabolic process GO:0009712 2 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
gtp catabolic process GO:0006184 2 0.012
phosphorus metabolic process GO:0006793 109 0.012
phosphorylation GO:0016310 69 0.012
negative regulation of signaling GO:0023057 96 0.012
negative regulation of multi organism process GO:0043901 3 0.012
negative regulation of cytokine production GO:0001818 1 0.012
organelle assembly GO:0070925 110 0.012
glucose homeostasis GO:0042593 1 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
embryonic skeletal system development GO:0048706 97 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
establishment of localization in cell GO:0051649 77 0.012
negative regulation of metabolic process GO:0009892 86 0.012
larval heart development GO:0007508 2 0.012
response to hypoxia GO:0001666 25 0.012
peripheral nervous system development GO:0007422 55 0.011
cellular response to hormone stimulus GO:0032870 39 0.011
cellular amine metabolic process GO:0044106 2 0.011
morphogenesis of an epithelium GO:0002009 333 0.011
response to estrogen GO:0043627 27 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
mitochondrion organization GO:0007005 4 0.011
response to oxygen containing compound GO:1901700 55 0.011
nuclear transport GO:0051169 4 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
chemosensory behavior GO:0007635 1 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
regulation of inflammatory response GO:0050727 2 0.011
positive regulation of catabolic process GO:0009896 4 0.011
positive regulation of signaling GO:0023056 56 0.011
Mouse
regulation of transmembrane transporter activity GO:0022898 2 0.011
Mouse
guanosine containing compound catabolic process GO:1901069 2 0.011
positive regulation of cell death GO:0010942 29 0.011
nitrogen compound transport GO:0071705 23 0.011
regulation of inhibitory postsynaptic membrane potential GO:0060080 1 0.011
Mouse
cellular protein metabolic process GO:0044267 129 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
gtp metabolic process GO:0046039 4 0.011
positive regulation of secretion GO:0051047 1 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
startle response GO:0001964 4 0.011
reproduction GO:0000003 40 0.011
Fly
regulation of hormone secretion GO:0046883 2 0.011
regulation of cell differentiation GO:0045595 142 0.011
Mouse
transmission of nerve impulse GO:0019226 19 0.011
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 1 0.010
positive regulation of secretion by cell GO:1903532 1 0.010
proteolysis GO:0006508 38 0.010
synapse organization GO:0050808 21 0.010
Human Mouse Fly
response to hexose GO:0009746 3 0.010
single organism membrane organization GO:0044802 20 0.010
Mouse Fly
muscle cell differentiation GO:0042692 139 0.010
neuromuscular synaptic transmission GO:0007274 2 0.010
Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.010
axon development GO:0061564 166 0.010
regulation of cellular protein catabolic process GO:1903362 1 0.010
transcription dna templated GO:0006351 181 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
regulation of nervous system development GO:0051960 90 0.010
Mouse
cellular response to decreased oxygen levels GO:0036294 1 0.010

nlgn3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.036
physical disorder DOID:0080015 0 0.014
congenital nervous system abnormality DOID:2490 0 0.014
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
pervasive developmental disorder DOID:0060040 0 0.010
Human
disease of mental health DOID:150 0 0.010
Human
developmental disorder of mental health DOID:0060037 0 0.010
Human