Danio rerio

0 known processes

gfap

glial fibrillary acidic protein

(Aliases: gfapl,wu:fk42c12,cb345,zgc:110485,etID36982.3,MGC110485,wu:fb34h11,xx:af506734)

gfap biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
developmental growth GO:0048589 166 0.445
generation of neurons GO:0048699 385 0.378
Zebrafish Mouse Rat
cell morphogenesis GO:0000902 289 0.363
Zebrafish
morphogenesis of an epithelium GO:0002009 333 0.333
heterocycle biosynthetic process GO:0018130 215 0.308
response to chemical GO:0042221 320 0.304
neuron differentiation GO:0030182 353 0.289
Zebrafish Mouse
neuron projection development GO:0031175 180 0.276
Zebrafish Mouse
lipid storage GO:0019915 1 0.234
tube morphogenesis GO:0035239 349 0.230
small molecule metabolic process GO:0044281 77 0.219
regulation of biological quality GO:0065008 263 0.206
Mouse
dopaminergic neuron differentiation GO:0071542 14 0.188
protein localization to nucleus GO:0034504 3 0.175
cell surface receptor signaling pathway GO:0007166 325 0.162
single organism transport GO:0044765 206 0.161
Mouse
angiogenesis GO:0001525 158 0.152
stem cell differentiation GO:0048863 117 0.150
cellular component movement GO:0006928 335 0.147
cell morphogenesis involved in differentiation GO:0000904 195 0.145
response to stress GO:0006950 263 0.145
Mouse Rat
regulation of multicellular organismal development GO:2000026 223 0.143
Mouse Rat
cell projection organization GO:0030030 284 0.132
Zebrafish Mouse
cell projection morphogenesis GO:0048858 244 0.129
Zebrafish
cellular component morphogenesis GO:0032989 336 0.127
Zebrafish
circulatory system process GO:0003013 87 0.123
Zebrafish
organonitrogen compound metabolic process GO:1901564 74 0.122
macromolecule modification GO:0043412 111 0.122
heart contraction GO:0060047 71 0.118
Zebrafish
regulation of multicellular organismal process GO:0051239 277 0.114
Mouse Rat
ventral spinal cord interneuron fate commitment GO:0060579 3 0.111
regulation of metabolic process GO:0019222 359 0.108
nucleobase containing compound biosynthetic process GO:0034654 205 0.107
cellular biosynthetic process GO:0044249 286 0.098
response to antibiotic GO:0046677 1 0.098
chemotaxis GO:0006935 104 0.098
aromatic compound biosynthetic process GO:0019438 217 0.097
cell part morphogenesis GO:0032990 246 0.096
Zebrafish
axon development GO:0061564 166 0.095
taxis GO:0042330 109 0.091
regulation of membrane potential GO:0042391 23 0.089
maintenance of location GO:0051235 4 0.088
membrane repolarization GO:0086009 2 0.088
neuron development GO:0048666 262 0.086
Zebrafish Mouse
locomotory behavior GO:0007626 34 0.085
response to radiation GO:0009314 51 0.084
positive regulation of metabolic process GO:0009893 108 0.083
mesenchymal cell development GO:0014031 78 0.082
heart development GO:0007507 313 0.079
localization of cell GO:0051674 244 0.079
regulation of developmental process GO:0050793 247 0.077
Mouse Rat
protein localization GO:0008104 40 0.069
eye development GO:0001654 277 0.068
axonogenesis GO:0007409 152 0.068
positive regulation of cellular process GO:0048522 201 0.068
Mouse Rat
response to metal ion GO:0010038 34 0.067
anterior commissure morphogenesis GO:0021960 3 0.067
biosynthetic process GO:0009058 294 0.067
system process GO:0003008 185 0.066
Zebrafish
gtp metabolic process GO:0046039 4 0.066
cell proliferation in forebrain GO:0021846 3 0.066
growth GO:0040007 174 0.064
muscle structure development GO:0061061 196 0.064
Zebrafish
regulation of oligodendrocyte differentiation GO:0048713 1 0.064
cell migration involved in heart development GO:0060973 22 0.064
stem cell proliferation GO:0072089 4 0.063
cardiocyte differentiation GO:0035051 44 0.061
positive regulation of transport GO:0051050 2 0.061
central nervous system myelination GO:0022010 2 0.060
regulation of cellular component organization GO:0051128 86 0.060
Mouse
response to abiotic stimulus GO:0009628 122 0.059
positive regulation of macromolecule metabolic process GO:0010604 93 0.058
astrocyte differentiation GO:0048708 1 0.057
Mouse
action potential GO:0001508 19 0.057
oxoacid metabolic process GO:0043436 31 0.057
epithelial tube morphogenesis GO:0060562 148 0.057
positive regulation of biological process GO:0048518 253 0.057
Mouse Rat
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.056
regulation of metal ion transport GO:0010959 4 0.056
mesenchymal cell differentiation GO:0048762 87 0.056
response to external stimulus GO:0009605 264 0.056
positive regulation of oligodendrocyte differentiation GO:0048714 1 0.056
neuron neuron synaptic transmission GO:0007270 1 0.056
regulation of molecular function GO:0065009 70 0.055
purine containing compound metabolic process GO:0072521 29 0.054
regulation of glial cell differentiation GO:0045685 4 0.054
organic substance biosynthetic process GO:1901576 289 0.052
cellular protein metabolic process GO:0044267 129 0.052
regulation of cellular amine metabolic process GO:0033238 0 0.051
abducens nucleus development GO:0021742 2 0.051
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.051
single organism metabolic process GO:0044710 217 0.051
cellular nitrogen compound metabolic process GO:0034641 290 0.050
regulation of dendrite development GO:0050773 3 0.049
regulation of nucleotide catabolic process GO:0030811 2 0.049
intracellular signal transduction GO:0035556 85 0.048
positive regulation of cellular component biogenesis GO:0044089 3 0.047
cell migration GO:0016477 237 0.047
regulation of nervous system development GO:0051960 90 0.047
Mouse Rat
vasculature development GO:0001944 278 0.045
neuron projection morphogenesis GO:0048812 161 0.045
Zebrafish
locomotion GO:0040011 313 0.045
negative regulation of response to stimulus GO:0048585 104 0.045
positive regulation of cellular catabolic process GO:0031331 3 0.045
ion homeostasis GO:0050801 41 0.045
regulation of catalytic activity GO:0050790 55 0.044
regulation of cellular amino acid metabolic process GO:0006521 0 0.044
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.044
positive regulation of catabolic process GO:0009896 4 0.044
regulation of signaling GO:0023051 235 0.044
Mouse
regulation of anatomical structure morphogenesis GO:0022603 130 0.044
regulation of cellular metabolic process GO:0031323 320 0.044
carboxylic acid metabolic process GO:0019752 22 0.043
regulation of cell morphogenesis GO:0022604 42 0.043
sensory organ development GO:0007423 393 0.043
sodium ion transport GO:0006814 24 0.042
positive regulation of muscle organ development GO:0048636 1 0.042
negative regulation of mitosis GO:0045839 3 0.041
organic acid metabolic process GO:0006082 31 0.041
cellular amine metabolic process GO:0044106 2 0.041
nucleobase containing compound metabolic process GO:0006139 274 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.040
auditory receptor cell fate determination GO:0042668 2 0.040
transport GO:0006810 220 0.039
Mouse
phosphate containing compound metabolic process GO:0006796 108 0.039
striated muscle cell differentiation GO:0051146 129 0.039
Zebrafish
neuroblast fate commitment GO:0014017 1 0.039
negative regulation of multicellular organismal process GO:0051241 69 0.038
Mouse
positive regulation of cell cycle GO:0045787 3 0.038
negative regulation of epithelial cell proliferation GO:0050680 1 0.038
nuclear import GO:0051170 3 0.037
neuroblast fate determination GO:0007400 1 0.037
positive regulation of molecular function GO:0044093 33 0.037
head development GO:0060322 303 0.037
cell cycle GO:0007049 93 0.036
heterocycle metabolic process GO:0046483 290 0.036
guanosine containing compound metabolic process GO:1901068 4 0.036
regulation of primary metabolic process GO:0080090 311 0.035
negative regulation of signal transduction GO:0009968 94 0.035
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.035
adult behavior GO:0030534 2 0.035
regulation of endothelial cell proliferation GO:0001936 1 0.035
negative regulation of gastrulation GO:2000542 11 0.035
nucleic acid metabolic process GO:0090304 244 0.034
positive regulation of cellular amine metabolic process GO:0033240 0 0.034
regionalization GO:0003002 274 0.034
regulation of neurogenesis GO:0050767 87 0.033
Mouse Rat
positive regulation of stem cell proliferation GO:2000648 1 0.033
amine metabolic process GO:0009308 2 0.033
neuroblast differentiation GO:0014016 1 0.033
regulation of establishment of protein localization GO:0070201 4 0.032
nuclear transport GO:0051169 4 0.031
behavior GO:0007610 74 0.031
stem cell development GO:0048864 82 0.031
blood vessel morphogenesis GO:0048514 216 0.031
camera type eye development GO:0043010 222 0.030
neuroblast proliferation GO:0007405 2 0.030
purine nucleoside monophosphate catabolic process GO:0009128 4 0.030
regulation of protein localization to nucleus GO:1900180 2 0.030
positive regulation of cell differentiation GO:0045597 30 0.030
Mouse Rat
cell motility GO:0048870 244 0.029
organic cyclic compound biosynthetic process GO:1901362 223 0.029
cellular protein modification process GO:0006464 100 0.029
negative regulation of protein phosphorylation GO:0001933 4 0.029
regulation of response to stimulus GO:0048583 269 0.029
regulation of axonogenesis GO:0050770 32 0.028
guanosine containing compound catabolic process GO:1901069 2 0.027
purine nucleotide metabolic process GO:0006163 27 0.027
regulation of jun kinase activity GO:0043506 3 0.027
regulation of cellular component movement GO:0051270 55 0.027
tissue regeneration GO:0042246 74 0.027
regulation of synaptic transmission GO:0050804 4 0.027
Mouse
regulation of intracellular protein transport GO:0033157 3 0.027
oligodendrocyte cell fate specification GO:0021778 4 0.027
cognition GO:0050890 1 0.026
axon ensheathment in central nervous system GO:0032291 2 0.026
protein metabolic process GO:0019538 183 0.026
developmental growth involved in morphogenesis GO:0060560 86 0.026
negative regulation of nuclear division GO:0051784 3 0.026
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.026
regulation of cell cycle GO:0051726 52 0.025
olfactory lobe development GO:0021988 4 0.025
signal transduction GO:0007165 455 0.025
somite development GO:0061053 96 0.025
neuron recognition GO:0008038 18 0.025
positive regulation of cellular metabolic process GO:0031325 94 0.025
brain development GO:0007420 293 0.025
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.025
positive regulation of catalytic activity GO:0043085 25 0.024
organic cyclic compound metabolic process GO:1901360 301 0.024
organelle organization GO:0006996 227 0.024
Zebrafish Mouse
segmentation GO:0035282 97 0.024
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.024
cellular macromolecule biosynthetic process GO:0034645 224 0.024
response to carbohydrate GO:0009743 3 0.023
aging GO:0007568 2 0.023
regulation of epithelial cell proliferation GO:0050678 3 0.023
carbohydrate derivative metabolic process GO:1901135 61 0.023
response to zinc ion GO:0010043 6 0.023
negative regulation of protein kinase activity GO:0006469 4 0.023
positive regulation of response to stimulus GO:0048584 80 0.023
positive regulation of blood circulation GO:1903524 2 0.023
cellular aromatic compound metabolic process GO:0006725 295 0.023
multicellular organism growth GO:0035264 4 0.023
nucleic acid templated transcription GO:0097659 181 0.023
protein import GO:0017038 3 0.022
regulation of transport GO:0051049 45 0.022
Mouse
regulation of cellular ketone metabolic process GO:0010565 7 0.022
inner ear receptor cell fate commitment GO:0060120 4 0.022
regulation of growth GO:0040008 42 0.022
blood vessel development GO:0001568 246 0.022
glutamate receptor signaling pathway GO:0007215 1 0.022
regulation of cell activation GO:0050865 1 0.022
regulation of neuron differentiation GO:0045664 56 0.022
Mouse
digestive system development GO:0055123 289 0.022
cardiac chamber formation GO:0003207 4 0.022
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.022
negative regulation of stem cell differentiation GO:2000737 2 0.021
negative regulation of cellular process GO:0048523 283 0.021
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.021
multicellular organismal signaling GO:0035637 22 0.021
actin mediated cell contraction GO:0070252 1 0.021
regulation of cell communication GO:0010646 232 0.021
Mouse
regulation of locomotion GO:0040012 55 0.021
stem cell fate commitment GO:0048865 1 0.021
regulation of rna biosynthetic process GO:2001141 213 0.021
determination of heart left right asymmetry GO:0061371 117 0.021
l amino acid transport GO:0015807 1 0.021
regulation of gtpase activity GO:0043087 2 0.020
atp catabolic process GO:0006200 4 0.020
central nervous system development GO:0007417 387 0.020
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.020
epithelial to mesenchymal transition GO:0001837 21 0.020
regulation of nucleocytoplasmic transport GO:0046822 2 0.020
cell adhesion GO:0007155 40 0.020
modification dependent protein catabolic process GO:0019941 3 0.019
protein modification process GO:0036211 100 0.019
phosphorylation GO:0016310 69 0.019
chemical homeostasis GO:0048878 49 0.019
muscle hypertrophy GO:0014896 2 0.019
peripheral nervous system development GO:0007422 55 0.019
cellular response to topologically incorrect protein GO:0035967 2 0.019
carbon dioxide transport GO:0015670 3 0.019
regulation of blood pressure GO:0008217 1 0.018
monovalent inorganic cation transport GO:0015672 42 0.018
regulation of cell differentiation GO:0045595 142 0.018
Mouse Rat
regulation of receptor mediated endocytosis GO:0048259 4 0.018
radial glial cell differentiation GO:0060019 2 0.018
water homeostasis GO:0030104 4 0.018
pancreatic a cell development GO:0003322 2 0.018
negative regulation of cellular component organization GO:0051129 16 0.018
Mouse
phosphorus metabolic process GO:0006793 109 0.018
regulation of growth rate GO:0040009 1 0.018
chordate embryonic development GO:0043009 271 0.018
sensory organ morphogenesis GO:0090596 200 0.018
muscle tissue development GO:0060537 110 0.018
cell recognition GO:0008037 19 0.018
mesenchyme development GO:0060485 127 0.018
synaptic target recognition GO:0008039 1 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
lymphocyte proliferation GO:0046651 1 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
positive regulation of muscle tissue development GO:1901863 1 0.017
negative regulation of neuron projection development GO:0010977 9 0.017
Mouse
regulation of cytoplasmic transport GO:1903649 4 0.017
rna biosynthetic process GO:0032774 181 0.017
ventricular system development GO:0021591 12 0.017
heart process GO:0003015 71 0.017
Zebrafish
transmission of nerve impulse GO:0019226 19 0.017
regeneration GO:0031099 91 0.017
Mouse
cellular ketone metabolic process GO:0042180 11 0.017
response to drug GO:0042493 3 0.016
gtp catabolic process GO:0006184 2 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
positive regulation of neural precursor cell proliferation GO:2000179 1 0.016
positive regulation of multicellular organismal process GO:0051240 52 0.016
Mouse Rat
negative regulation of catabolic process GO:0009895 3 0.016
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.016
endothelial cell proliferation GO:0001935 11 0.016
regulation of cell development GO:0060284 100 0.016
Mouse Rat
receptor internalization GO:0031623 2 0.016
regulation of heart contraction GO:0008016 32 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
negative regulation of endothelial cell migration GO:0010596 1 0.015
cell proliferation in hindbrain GO:0021534 4 0.015
negative regulation of mesodermal cell fate specification GO:0042662 3 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
glial cell development GO:0021782 20 0.015
Mouse
canonical wnt signaling pathway GO:0060070 48 0.015
ameboidal type cell migration GO:0001667 143 0.015
regulation of cell projection organization GO:0031344 44 0.015
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.015
regulation of cell size GO:0008361 29 0.015
response to vitamin GO:0033273 3 0.015
camera type eye morphogenesis GO:0048593 108 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
glial cell fate specification GO:0021780 4 0.015
ventral spinal cord development GO:0021517 35 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
stem cell fate determination GO:0048867 1 0.015
specification of symmetry GO:0009799 204 0.015
lipid catabolic process GO:0016042 4 0.014
enteroendocrine cell differentiation GO:0035883 9 0.014
wound healing GO:0042060 90 0.014
developmental programmed cell death GO:0010623 4 0.014
semicircular canal development GO:0060872 24 0.014
regulation of protein targeting GO:1903533 2 0.014
muscle cell development GO:0055001 115 0.014
Zebrafish
neural crest cell development GO:0014032 62 0.014
fatty acid oxidation GO:0019395 1 0.014
blood circulation GO:0008015 87 0.014
Zebrafish
oligodendrocyte differentiation GO:0048709 23 0.014
cellular response to radiation GO:0071478 4 0.013
immune system process GO:0002376 241 0.013
regulation of phosphorus metabolic process GO:0051174 43 0.013
regulation of cellular component size GO:0032535 30 0.013
actin filament based movement GO:0030048 1 0.013
modification dependent macromolecule catabolic process GO:0043632 3 0.013
synaptic transmission GO:0007268 35 0.013
Mouse
negative regulation of nervous system development GO:0051961 22 0.013
Mouse
axis specification GO:0009798 43 0.013
renal absorption GO:0070293 1 0.013
organ regeneration GO:0031100 1 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
glucose homeostasis GO:0042593 1 0.013
regulation of organ growth GO:0046620 3 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
glucose import GO:0046323 2 0.013
regulation of localization GO:0032879 104 0.013
Mouse
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.013
protein import into nucleus GO:0006606 3 0.013
lipid metabolic process GO:0006629 52 0.012
signal transduction in absence of ligand GO:0038034 1 0.012
regulation of developmental growth GO:0048638 38 0.012
glycolipid biosynthetic process GO:0009247 1 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
ion transmembrane transport GO:0034220 91 0.012
regulation of phosphate metabolic process GO:0019220 43 0.012
positive regulation of translation GO:0045727 1 0.012
gland development GO:0048732 143 0.012
regulation of system process GO:0044057 40 0.012
cellular response to external stimulus GO:0071496 2 0.012
positive regulation of cell communication GO:0010647 56 0.012
Mouse
organic substance transport GO:0071702 58 0.012
response to inorganic substance GO:0010035 38 0.012
regulation of biosynthetic process GO:0009889 250 0.012
retina development in camera type eye GO:0060041 146 0.012
cellular response to unfolded protein GO:0034620 2 0.012
dendrite guidance GO:0070983 0 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.012
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.012
homeostatic process GO:0042592 142 0.012
peripheral nervous system neuron development GO:0048935 22 0.012
regulation of kinase activity GO:0043549 15 0.012
response to unfolded protein GO:0006986 2 0.012
positive regulation of striated muscle tissue development GO:0045844 1 0.012
inorganic ion transmembrane transport GO:0098660 57 0.012
regulation of multicellular organism growth GO:0040014 4 0.012
cation transport GO:0006812 81 0.012
macromolecular complex subunit organization GO:0043933 74 0.011
Mouse
sarcomere organization GO:0045214 26 0.011
Zebrafish
periodic partitioning GO:0007365 1 0.011
cell growth GO:0016049 57 0.011
olfactory bulb axon guidance GO:0071678 3 0.011
cellular response to oxygen levels GO:0071453 1 0.011
establishment of protein localization to organelle GO:0072594 4 0.011
regulation of tube size GO:0035150 2 0.011
regulation of cell proliferation GO:0042127 37 0.011
Mouse Rat
nucleobase containing small molecule metabolic process GO:0055086 32 0.011
er nucleus signaling pathway GO:0006984 2 0.011
regulation of hydrolase activity GO:0051336 28 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
peptide transport GO:0015833 1 0.011
ion transport GO:0006811 114 0.011
regulation of wound healing GO:0061041 2 0.011
immune system development GO:0002520 191 0.011
glial cell fate determination GO:0007403 1 0.011
single organism behavior GO:0044708 24 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
negative chemotaxis GO:0050919 1 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
medulla oblongata development GO:0021550 4 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
negative regulation of axon extension GO:0030517 7 0.011
response to acid chemical GO:0001101 17 0.011
startle response GO:0001964 4 0.011
ear development GO:0043583 127 0.011
regulation of fatty acid metabolic process GO:0019217 1 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.011
cellular response to starvation GO:0009267 1 0.011
regulation of cellular protein metabolic process GO:0032268 52 0.010
regulation of dendrite morphogenesis GO:0048814 3 0.010
ventral spinal cord interneuron differentiation GO:0021514 12 0.010
nucleocytoplasmic transport GO:0006913 4 0.010
regulation of protein metabolic process GO:0051246 56 0.010
convergent extension GO:0060026 118 0.010
embryonic organ development GO:0048568 381 0.010
response to monosaccharide GO:0034284 3 0.010
positive regulation of cell division GO:0051781 2 0.010
nucleoside triphosphate metabolic process GO:0009141 9 0.010
sodium ion transmembrane transport GO:0035725 21 0.010
negative regulation of cell communication GO:0010648 96 0.010

gfap disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.087
Human
nervous system disease DOID:863 0 0.087
Human
cerebral degeneration DOID:1443 0 0.020
Human
central nervous system disease DOID:331 0 0.020
Human
brain disease DOID:936 0 0.020
Human
leukodystrophy DOID:10579 0 0.020
Human