Danio rerio

0 known processes

adora2ab

adenosine A2a receptor b

(Aliases: zgc:193822,zgc:193802,adora2a.2)

adora2ab biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
signal transduction GO:0007165 455 0.115
amine metabolic process GO:0009308 2 0.107
organonitrogen compound metabolic process GO:1901564 74 0.083
biosynthetic process GO:0009058 294 0.080
cellular biosynthetic process GO:0044249 286 0.078
neuron development GO:0048666 262 0.077
cellular amine metabolic process GO:0044106 2 0.075
startle response GO:0001964 4 0.068
central nervous system development GO:0007417 387 0.068
regulation of cellular amine metabolic process GO:0033238 0 0.066
regulation of reproductive process GO:2000241 4 0.065
larval development GO:0002164 2 0.064
peptidyl serine phosphorylation GO:0018105 1 0.063
protein localization to nucleus GO:0034504 3 0.062
aging GO:0007568 2 0.061
reactive nitrogen species metabolic process GO:2001057 0 0.060
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.057
generation of neurons GO:0048699 385 0.056
regulation of signal transduction GO:0009966 225 0.055
regulation of programmed cell death GO:0043067 101 0.054
single organism metabolic process GO:0044710 217 0.054
small molecule metabolic process GO:0044281 77 0.054
neuron differentiation GO:0030182 353 0.054
head development GO:0060322 303 0.052
eye development GO:0001654 277 0.052
regulation of cellular amino acid metabolic process GO:0006521 0 0.050
positive regulation of transport GO:0051050 2 0.049
cell surface receptor signaling pathway GO:0007166 325 0.049
compound eye development GO:0048749 2 0.048
response to organic substance GO:0010033 153 0.048
regulation of biological quality GO:0065008 263 0.045
Zebrafish
organic acid metabolic process GO:0006082 31 0.043
nitrogen compound metabolic process GO:0006807 319 0.041
regulation of cell communication GO:0010646 232 0.041
response to amine GO:0014075 1 0.041
cellular ketone metabolic process GO:0042180 11 0.041
cellular amino acid metabolic process GO:0006520 7 0.039
cell part morphogenesis GO:0032990 246 0.039
protein import GO:0017038 3 0.039
protein import into nucleus GO:0006606 3 0.039
regulation of macromolecule metabolic process GO:0060255 317 0.038
protein metabolic process GO:0019538 183 0.038
regulation of establishment of protein localization GO:0070201 4 0.037
response to chemical GO:0042221 320 0.037
regulation of metabolic process GO:0019222 359 0.037
regionalization GO:0003002 274 0.037
organic substance biosynthetic process GO:1901576 289 0.036
morphogenesis of an epithelium GO:0002009 333 0.036
multicellular organism growth GO:0035264 4 0.034
regulation of epithelial cell proliferation GO:0050678 3 0.034
neuron projection development GO:0031175 180 0.034
response to amino acid GO:0043200 2 0.033
neuroblast proliferation GO:0007405 2 0.033
adult behavior GO:0030534 2 0.033
single organism nuclear import GO:1902593 3 0.033
regulation of metal ion transport GO:0010959 4 0.033
vasculature development GO:0001944 278 0.032
digestive system development GO:0055123 289 0.032
stem cell fate commitment GO:0048865 1 0.032
cognition GO:0050890 1 0.031
protein targeting to nucleus GO:0044744 3 0.031
ion transmembrane transport GO:0034220 91 0.031
regulation of cellular ketone metabolic process GO:0010565 7 0.030
synaptic growth at neuromuscular junction GO:0051124 2 0.030
digestive tract morphogenesis GO:0048546 231 0.030
reactive oxygen species biosynthetic process GO:1903409 1 0.030
cellular response to extracellular stimulus GO:0031668 2 0.029
nuclear import GO:0051170 3 0.029
positive regulation of cell cycle GO:0045787 3 0.029
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.029
response to alkaloid GO:0043279 2 0.029
cellular response to external stimulus GO:0071496 2 0.029
regulation of wound healing GO:0061041 2 0.029
organic cyclic compound metabolic process GO:1901360 301 0.028
water homeostasis GO:0030104 4 0.028
gene expression GO:0010467 252 0.028
nuclear transport GO:0051169 4 0.027
stem cell proliferation GO:0072089 4 0.027
behavior GO:0007610 74 0.027
regulation of signaling GO:0023051 235 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.027
hormone secretion GO:0046879 2 0.026
lipid storage GO:0019915 1 0.026
response to stress GO:0006950 263 0.026
regulation of cytoplasmic transport GO:1903649 4 0.026
kupffer s vesicle development GO:0070121 50 0.026
cellular response to organic substance GO:0071310 105 0.026
establishment of protein localization to organelle GO:0072594 4 0.026
regulation of response to stimulus GO:0048583 269 0.026
heart contraction GO:0060047 71 0.026
Zebrafish
nucleobase containing compound biosynthetic process GO:0034654 205 0.026
cell projection morphogenesis GO:0048858 244 0.026
system process GO:0003008 185 0.025
Zebrafish
positive regulation of cellular amine metabolic process GO:0033240 0 0.025
regulation of intracellular protein transport GO:0033157 3 0.025
atp catabolic process GO:0006200 4 0.025
regulation of sodium ion transport GO:0002028 2 0.025
nucleocytoplasmic transport GO:0006913 4 0.025
muscle tissue development GO:0060537 110 0.025
somite development GO:0061053 96 0.025
cell morphogenesis GO:0000902 289 0.025
axon ensheathment in central nervous system GO:0032291 2 0.024
death GO:0016265 121 0.024
response to nutrient GO:0007584 3 0.024
renal system development GO:0072001 94 0.024
positive regulation of cellular catabolic process GO:0031331 3 0.024
maintenance of location GO:0051235 4 0.024
immune system process GO:0002376 241 0.024
nitric oxide metabolic process GO:0046209 2 0.024
regulation of circadian rhythm GO:0042752 4 0.024
regulation of protein transport GO:0051223 3 0.024
heterocycle metabolic process GO:0046483 290 0.024
carbohydrate derivative biosynthetic process GO:1901137 43 0.024
regulation of multicellular organism growth GO:0040014 4 0.023
neuron neuron synaptic transmission GO:0007270 1 0.023
regulation of nucleocytoplasmic transport GO:0046822 2 0.023
guanosine containing compound metabolic process GO:1901068 4 0.023
regulation of membrane potential GO:0042391 23 0.023
positive regulation of catabolic process GO:0009896 4 0.023
post embryonic organ development GO:0048569 4 0.023
carboxylic acid metabolic process GO:0019752 22 0.023
cellular response to lipopolysaccharide GO:0071222 3 0.023
hormone transport GO:0009914 2 0.023
hormone mediated signaling pathway GO:0009755 9 0.023
positive regulation of reproductive process GO:2000243 2 0.023
regulation of synapse assembly GO:0051963 3 0.023
somitogenesis GO:0001756 87 0.023
camera type eye development GO:0043010 222 0.022
regulation of protein targeting GO:1903533 2 0.022
transmembrane transport GO:0055085 120 0.022
regulation of apoptotic process GO:0042981 98 0.022
developmental growth GO:0048589 166 0.022
regulation of binding GO:0051098 3 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.022
digestive tract development GO:0048565 265 0.022
oxoacid metabolic process GO:0043436 31 0.022
regulation of carbohydrate metabolic process GO:0006109 4 0.022
nitric oxide biosynthetic process GO:0006809 2 0.021
determination of bilateral symmetry GO:0009855 204 0.021
g protein coupled receptor signaling pathway GO:0007186 74 0.021
peptidyl serine modification GO:0018209 2 0.021
sensory organ development GO:0007423 393 0.021
regulation of transporter activity GO:0032409 2 0.021
regulation of muscle contraction GO:0006937 3 0.021
response to carbohydrate GO:0009743 3 0.021
regulation of multicellular organismal process GO:0051239 277 0.021
ribonucleoside monophosphate catabolic process GO:0009158 4 0.021
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.021
peptidyl threonine phosphorylation GO:0018107 1 0.020
striated muscle tissue development GO:0014706 110 0.020
cellular response to biotic stimulus GO:0071216 3 0.020
phosphate containing compound metabolic process GO:0006796 108 0.020
cellular macromolecule metabolic process GO:0044260 391 0.020
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.020
regulation of protein localization to nucleus GO:1900180 2 0.020
anion transport GO:0006820 38 0.020
negative regulation of response to stimulus GO:0048585 104 0.020
cellular response to chemical stimulus GO:0070887 157 0.020
dopamine metabolic process GO:0042417 2 0.020
inorganic cation transmembrane transport GO:0098662 50 0.020
locomotory behavior GO:0007626 34 0.020
inorganic ion transmembrane transport GO:0098660 57 0.020
protein dephosphorylation GO:0006470 3 0.020
regulation of neural precursor cell proliferation GO:2000177 3 0.020
regulation of synapse organization GO:0050807 3 0.020
response to endogenous stimulus GO:0009719 83 0.020
regulation of ion transmembrane transporter activity GO:0032412 2 0.019
alcohol biosynthetic process GO:0046165 2 0.019
regulation of developmental process GO:0050793 247 0.019
response to vitamin GO:0033273 3 0.019
chemosensory behavior GO:0007635 1 0.019
single organism reproductive process GO:0044702 40 0.019
axonogenesis GO:0007409 152 0.019
melanin metabolic process GO:0006582 2 0.019
determination of left right symmetry GO:0007368 179 0.019
regulation of primary metabolic process GO:0080090 311 0.019
catecholamine metabolic process GO:0006584 2 0.019
negative regulation of mapk cascade GO:0043409 4 0.019
cation transmembrane transport GO:0098655 65 0.019
cell projection organization GO:0030030 284 0.019
segmentation GO:0035282 97 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
peptide transport GO:0015833 1 0.019
nucleobase containing compound metabolic process GO:0006139 274 0.018
response to amphetamine GO:0001975 1 0.018
negative regulation of cellular process GO:0048523 283 0.018
microtubule polymerization or depolymerization GO:0031109 3 0.018
regulation of cellular metabolic process GO:0031323 320 0.018
regulation of calcium ion transport GO:0051924 2 0.018
cytokinesis GO:0000910 3 0.018
positive regulation of biological process GO:0048518 253 0.018
negative regulation of biological process GO:0048519 304 0.018
exocytosis GO:0006887 1 0.018
sleep GO:0030431 1 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
cellular protein catabolic process GO:0044257 4 0.018
regulation of cell activation GO:0050865 1 0.018
response to drug GO:0042493 3 0.018
regulation of hormone secretion GO:0046883 2 0.018
cytoskeleton dependent cytokinesis GO:0061640 3 0.018
negative regulation of intracellular transport GO:0032387 3 0.017
regulation of systemic arterial blood pressure GO:0003073 1 0.017
cellular nitrogen compound metabolic process GO:0034641 290 0.017
multi organism process GO:0051704 134 0.017
gastrulation GO:0007369 208 0.017
phosphorylation GO:0016310 69 0.017
secondary metabolic process GO:0019748 3 0.017
cell death GO:0008219 121 0.017
single organism biosynthetic process GO:0044711 71 0.017
blood vessel development GO:0001568 246 0.017
regulation of ion transmembrane transport GO:0034765 18 0.017
brain development GO:0007420 293 0.017
ear development GO:0043583 127 0.017
cellular component movement GO:0006928 335 0.017
negative regulation of catabolic process GO:0009895 3 0.017
response to hexose GO:0009746 3 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
regulation of tube size GO:0035150 2 0.017
cellular response to starvation GO:0009267 1 0.017
nucleoside monophosphate catabolic process GO:0009125 4 0.017
regulation of protein catabolic process GO:0042176 1 0.017
regulation of blood pressure GO:0008217 1 0.016
gland development GO:0048732 143 0.016
single organism transport GO:0044765 206 0.016
peptidyl threonine modification GO:0018210 1 0.016
blood vessel morphogenesis GO:0048514 216 0.016
epidermal cell fate specification GO:0009957 4 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
cellular component assembly GO:0022607 170 0.016
regulation of transmembrane transporter activity GO:0022898 2 0.016
regulation of nitrogen compound metabolic process GO:0051171 251 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
autophagy GO:0006914 4 0.016
peptide metabolic process GO:0006518 1 0.016
response to monosaccharide GO:0034284 3 0.016
lipid homeostasis GO:0055088 3 0.015
establishment of endothelial barrier GO:0061028 3 0.015
carbohydrate derivative metabolic process GO:1901135 61 0.015
regulation of protein complex assembly GO:0043254 3 0.015
regulation of blood vessel size GO:0050880 2 0.015
phagocytosis GO:0006909 3 0.015
dorsal ventral pattern formation GO:0009953 125 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
enzyme linked receptor protein signaling pathway GO:0007167 106 0.015
stem cell maintenance GO:0019827 4 0.015
neurotransmitter transport GO:0006836 2 0.015
neurotransmitter secretion GO:0007269 2 0.015
sensory organ morphogenesis GO:0090596 200 0.015
monoamine transport GO:0015844 1 0.015
heart process GO:0003015 71 0.015
Zebrafish
angiogenesis GO:0001525 158 0.015
long chain fatty acid transport GO:0015909 1 0.015
negative regulation of macromolecule metabolic process GO:0010605 76 0.015
cellular macromolecule biosynthetic process GO:0034645 224 0.015
locomotion GO:0040011 313 0.015
regulation of skeletal muscle tissue development GO:0048641 4 0.015
regulation of biosynthetic process GO:0009889 250 0.015
gtp metabolic process GO:0046039 4 0.015
negative regulation of intracellular protein transport GO:0090317 3 0.015
cellular response to nutrient levels GO:0031669 2 0.015
multicellular organismal response to stress GO:0033555 2 0.015
neurological system process GO:0050877 62 0.015
epithelial tube morphogenesis GO:0060562 148 0.015
regulation of protein polymerization GO:0032271 2 0.015
positive regulation of neural precursor cell proliferation GO:2000179 1 0.015
negative regulation of kinase activity GO:0033673 4 0.015
catechol containing compound metabolic process GO:0009712 2 0.014
muscle structure development GO:0061061 196 0.014
morphogenesis of an epithelial fold GO:0060571 1 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
protein stabilization GO:0050821 2 0.014
circulatory system process GO:0003013 87 0.014
Zebrafish
transport GO:0006810 220 0.014
rna biosynthetic process GO:0032774 181 0.014
calcium mediated signaling GO:0019722 2 0.014
regulation of dendrite development GO:0050773 3 0.014
stem cell differentiation GO:0048863 117 0.014
positive regulation of stem cell proliferation GO:2000648 1 0.014
meiotic nuclear division GO:0007126 4 0.014
cellular component disassembly GO:0022411 1 0.014
tissue remodeling GO:0048771 4 0.014
response to radiation GO:0009314 51 0.014
positive regulation of camp metabolic process GO:0030816 2 0.014
regulation of reactive oxygen species metabolic process GO:2000377 2 0.014
astrocyte differentiation GO:0048708 1 0.014
cellular response to decreased oxygen levels GO:0036294 1 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
negative regulation of cytoplasmic transport GO:1903650 2 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
cytokinetic process GO:0032506 2 0.014
specification of symmetry GO:0009799 204 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.014
maternal determination of anterior posterior axis embryo GO:0008358 4 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
cellular response to estrogen stimulus GO:0071391 24 0.013
sex determination GO:0007530 1 0.013
protein localization to plasma membrane GO:0072659 1 0.013
response to corticosteroid GO:0031960 1 0.013
cellular component biogenesis GO:0044085 178 0.013
action potential GO:0001508 19 0.013
embryonic heart tube morphogenesis GO:0003143 108 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
regulation of cell death GO:0010941 103 0.013
negative regulation of gliogenesis GO:0014014 1 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
homeostatic process GO:0042592 142 0.013
Zebrafish
cellular nitrogen compound biosynthetic process GO:0044271 218 0.013
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
calcium ion transport into cytosol GO:0060402 3 0.013
rhombomere 6 development GO:0021572 4 0.013
protein complex disassembly GO:0043241 1 0.013
negative regulation of protein transport GO:0051224 3 0.013
glial cell differentiation GO:0010001 42 0.013
cellular aromatic compound metabolic process GO:0006725 295 0.013
negative regulation of metabolic process GO:0009892 86 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
oocyte anterior posterior axis specification GO:0007314 4 0.013
somatic muscle development GO:0007525 4 0.013
pigmentation GO:0043473 85 0.013
regulation of filopodium assembly GO:0051489 2 0.013
regulation of microtubule cytoskeleton organization GO:0070507 3 0.013
negative regulation of signaling GO:0023057 96 0.013
cellular component morphogenesis GO:0032989 336 0.012
regulation of glial cell differentiation GO:0045685 4 0.012
anterior posterior pattern specification GO:0009952 152 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.012
positive regulation of blood circulation GO:1903524 2 0.012
regulation of gene expression GO:0010468 265 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
response to glucose GO:0009749 3 0.012
notochord development GO:0030903 54 0.012
bmp signaling pathway GO:0030509 52 0.012
protein polymerization GO:0051258 4 0.012
negative regulation of protein phosphorylation GO:0001933 4 0.012
ear morphogenesis GO:0042471 64 0.012
regulation of neurotransmitter transport GO:0051588 1 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
glycoprotein metabolic process GO:0009100 23 0.012
positive regulation of wound healing GO:0090303 1 0.012
muscle cell development GO:0055001 115 0.012
organelle localization GO:0051640 49 0.012
positive regulation of multi organism process GO:0043902 3 0.012
aromatic compound biosynthetic process GO:0019438 217 0.012
embryonic organ development GO:0048568 381 0.012
single organism cellular localization GO:1902580 46 0.012
mitochondrion organization GO:0007005 4 0.012
response to hormone GO:0009725 48 0.012
regulation of cytokine production GO:0001817 3 0.012
sequestering of metal ion GO:0051238 3 0.012
neural retina development GO:0003407 49 0.011
response to uv GO:0009411 3 0.011
gtp catabolic process GO:0006184 2 0.011
positive regulation of cell activation GO:0050867 1 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
response to wounding GO:0009611 116 0.011
homeostasis of number of cells within a tissue GO:0048873 4 0.011
Zebrafish
response to glucocorticoid GO:0051384 1 0.011
regulation of cellular biosynthetic process GO:0031326 245 0.011
lipid catabolic process GO:0016042 4 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
regulation of gtpase activity GO:0043087 2 0.011
regulation of molecular function GO:0065009 70 0.011
positive regulation of secretion GO:0051047 1 0.011
organelle organization GO:0006996 227 0.011
hatching GO:0035188 4 0.011
macromolecule biosynthetic process GO:0009059 227 0.011
chordate embryonic development GO:0043009 271 0.011
fertilization GO:0009566 3 0.011
sodium ion transmembrane transport GO:0035725 21 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
cellular response to reactive oxygen species GO:0034614 2 0.011
adherens junction organization GO:0034332 4 0.011
proteolysis GO:0006508 38 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
neuronal action potential GO:0019228 18 0.011
regulation of inflammatory response GO:0050727 2 0.011
fatty acid transport GO:0015908 1 0.011
regulation of autophagy GO:0010506 3 0.011
cellular response to oxygen levels GO:0071453 1 0.011
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
rna metabolic process GO:0016070 219 0.011
central nervous system myelination GO:0022010 2 0.011
heart development GO:0007507 313 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
macromolecule modification GO:0043412 111 0.011
positive regulation of cell communication GO:0010647 56 0.011
synaptic vesicle localization GO:0097479 1 0.011
lipid metabolic process GO:0006629 52 0.011
carbohydrate homeostasis GO:0033500 1 0.011
b cell mediated immunity GO:0019724 3 0.011
multicellular organismal signaling GO:0035637 22 0.011
b cell activation GO:0042113 2 0.011
intracellular signal transduction GO:0035556 85 0.011
negative regulation of protein localization to nucleus GO:1900181 2 0.011
mononuclear cell proliferation GO:0032943 1 0.010
regulation of purine nucleotide catabolic process GO:0033121 2 0.010
chemical homeostasis GO:0048878 49 0.010
energy reserve metabolic process GO:0006112 2 0.010
membrane fusion GO:0061025 2 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
regulation of rna metabolic process GO:0051252 224 0.010
establishment of localization GO:0051234 244 0.010
rna localization GO:0006403 4 0.010
regulation of sodium ion transmembrane transport GO:1902305 1 0.010
striated muscle cell differentiation GO:0051146 129 0.010
positive regulation of exocytosis GO:0045921 1 0.010
organic cyclic compound biosynthetic process GO:1901362 223 0.010
inner ear development GO:0048839 126 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
urogenital system development GO:0001655 97 0.010
positive regulation of protein complex assembly GO:0031334 2 0.010
regulation of cell shape GO:0008360 1 0.010
regulation of oocyte development GO:0060281 3 0.010
smooth muscle contraction GO:0006939 2 0.010

adora2ab disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
cancer DOID:162 0 0.031
disease of cellular proliferation DOID:14566 0 0.031
nervous system disease DOID:863 0 0.017
immune system disease DOID:2914 0 0.015
organ system cancer DOID:0050686 0 0.012