Danio rerio

0 known processes

has3

hyaluronan synthase 3

(Aliases: xx:af190743gs2,xx:af190743gs1,dg42III)

has3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
anterior posterior pattern specification GO:0009952 152 0.168
Zebrafish
cellular component movement GO:0006928 335 0.140
Zebrafish
regulation of sequestering of calcium ion GO:0051282 4 0.133
regulation of multicellular organismal process GO:0051239 277 0.132
Zebrafish
somite development GO:0061053 96 0.119
Zebrafish
cell motility GO:0048870 244 0.114
Zebrafish
development of primary female sexual characteristics GO:0046545 4 0.109
inner ear development GO:0048839 126 0.104
cellular response to external stimulus GO:0071496 2 0.103
sequestering of calcium ion GO:0051208 3 0.097
negative regulation of biological process GO:0048519 304 0.095
sensory organ development GO:0007423 393 0.095
somitogenesis GO:0001756 87 0.094
Zebrafish
heart development GO:0007507 313 0.092
Zebrafish
regulation of cellular metabolic process GO:0031323 320 0.087
Zebrafish
embryonic digestive tract morphogenesis GO:0048557 3 0.086
segmentation GO:0035282 97 0.084
Zebrafish
response to chemical GO:0042221 320 0.083
embryo development ending in birth or egg hatching GO:0009792 271 0.082
Zebrafish
cell migration GO:0016477 237 0.081
Zebrafish
signal transduction GO:0007165 455 0.080
Zebrafish
growth plate cartilage morphogenesis GO:0003422 1 0.080
positive regulation of cell cycle GO:0045787 3 0.078
cell part morphogenesis GO:0032990 246 0.076
chordate embryonic development GO:0043009 271 0.076
Zebrafish
ion transport GO:0006811 114 0.074
regulation of metabolic process GO:0019222 359 0.071
Zebrafish
regulation of anterior head development GO:2000742 2 0.069
growth GO:0040007 174 0.068
metal ion homeostasis GO:0055065 26 0.066
regulation of response to stimulus GO:0048583 269 0.066
Zebrafish
anterior head development GO:0097065 2 0.065
eye development GO:0001654 277 0.061
larval development GO:0002164 2 0.061
specification of axis polarity GO:0065001 4 0.059
embryonic organ morphogenesis GO:0048562 274 0.058
Zebrafish
release of sequestered calcium ion into cytosol GO:0051209 3 0.058
regulation of biosynthetic process GO:0009889 250 0.058
Zebrafish
regulation of cell communication GO:0010646 232 0.058
Zebrafish
aging GO:0007568 2 0.056
regulation of behavior GO:0050795 24 0.056
sequestering of metal ion GO:0051238 3 0.055
ectodermal placode morphogenesis GO:0071697 32 0.054
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.053
cellular component assembly GO:0022607 170 0.053
Mouse
heart morphogenesis GO:0003007 156 0.052
Zebrafish
cytosolic calcium ion transport GO:0060401 3 0.052
cellular nitrogen compound biosynthetic process GO:0044271 218 0.052
negative regulation of sequestering of calcium ion GO:0051283 4 0.052
cellular macromolecule metabolic process GO:0044260 391 0.051
Mouse
embryonic cranial skeleton morphogenesis GO:0048701 90 0.050
cell morphogenesis GO:0000902 289 0.049
regulation of tube size GO:0035150 2 0.049
transport GO:0006810 220 0.049
cytoskeleton organization GO:0007010 96 0.049
nucleic acid templated transcription GO:0097659 181 0.049
positive regulation of transport GO:0051050 2 0.049
specification of symmetry GO:0009799 204 0.048
Zebrafish
negative regulation of multicellular organismal process GO:0051241 69 0.048
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.047
Zebrafish
cellular aromatic compound metabolic process GO:0006725 295 0.047
extrinsic apoptotic signaling pathway GO:0097191 3 0.046
stem cell differentiation GO:0048863 117 0.046
protein metabolic process GO:0019538 183 0.046
cation homeostasis GO:0055080 33 0.046
cellular component morphogenesis GO:0032989 336 0.046
cell morphogenesis involved in differentiation GO:0000904 195 0.045
homeostatic process GO:0042592 142 0.044
calcium ion transport into cytosol GO:0060402 3 0.044
morphogenesis of an epithelium GO:0002009 333 0.044
Zebrafish
neurotransmitter transport GO:0006836 2 0.043
direct ossification GO:0036072 3 0.043
single organism localization GO:1902578 225 0.043
regulation of macromolecule metabolic process GO:0060255 317 0.042
Zebrafish
negative regulation of heart contraction GO:0045822 2 0.041
positive regulation of blood circulation GO:1903524 2 0.040
single organism biosynthetic process GO:0044711 71 0.040
Mouse
skeletal system development GO:0001501 181 0.039
axon guidance GO:0007411 86 0.039
embryonic skeletal system morphogenesis GO:0048704 93 0.039
striated muscle cell development GO:0055002 108 0.038
regulation of skeletal muscle tissue development GO:0048641 4 0.038
embryonic skeletal system development GO:0048706 97 0.038
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.037
hematopoietic or lymphoid organ development GO:0048534 191 0.037
nucleic acid metabolic process GO:0090304 244 0.036
negative regulation of feeding behavior GO:2000252 2 0.036
neuron projection guidance GO:0097485 86 0.036
ear development GO:0043583 127 0.036
maintenance of location GO:0051235 4 0.036
organelle organization GO:0006996 227 0.035
biosynthetic process GO:0009058 294 0.035
Mouse
heterocycle biosynthetic process GO:0018130 215 0.035
regulation of reproductive process GO:2000241 4 0.035
negative regulation of cellular process GO:0048523 283 0.034
multicellular organismal metabolic process GO:0044236 2 0.034
regulation of macromolecule biosynthetic process GO:0010556 225 0.034
Zebrafish
regulation of extent of cell growth GO:0061387 29 0.033
kupffer s vesicle development GO:0070121 50 0.033
cell death GO:0008219 121 0.033
neural tube patterning GO:0021532 33 0.033
nitrogen compound metabolic process GO:0006807 319 0.033
Mouse
neuron projection morphogenesis GO:0048812 161 0.032
regulation of calcium ion transport GO:0051924 2 0.032
motor neuron axon guidance GO:0008045 23 0.031
thrombocyte differentiation GO:0002574 4 0.031
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.031
cellular nitrogen compound metabolic process GO:0034641 290 0.031
programmed cell death GO:0012501 119 0.031
regionalization GO:0003002 274 0.030
Zebrafish
exocytosis GO:0006887 1 0.030
organonitrogen compound metabolic process GO:1901564 74 0.030
Mouse
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.029
tissue remodeling GO:0048771 4 0.029
stem cell proliferation GO:0072089 4 0.029
positive regulation of catabolic process GO:0009896 4 0.029
localization of cell GO:0051674 244 0.029
Zebrafish
positive regulation of cellular catabolic process GO:0031331 3 0.029
notochord development GO:0030903 54 0.029
modification dependent protein catabolic process GO:0019941 3 0.029
synaptic transmission cholinergic GO:0007271 4 0.028
cytokinesis GO:0000910 3 0.028
regulation of nitrogen compound metabolic process GO:0051171 251 0.028
Zebrafish
multicellular organismal homeostasis GO:0048871 29 0.028
regulation of cytoplasmic transport GO:1903649 4 0.028
neuromast development GO:0048884 46 0.028
cardiac cell fate commitment GO:0060911 1 0.027
response to steroid hormone GO:0048545 35 0.027
response to organic substance GO:0010033 153 0.027
regulation of multicellular organismal metabolic process GO:0044246 2 0.027
epithelial cell morphogenesis GO:0003382 2 0.026
gall bladder development GO:0061010 1 0.026
heterocycle metabolic process GO:0046483 290 0.026
post embryonic organ development GO:0048569 4 0.026
epithelial tube morphogenesis GO:0060562 148 0.026
Zebrafish
cation transport GO:0006812 81 0.026
establishment of localization GO:0051234 244 0.026
synaptic growth at neuromuscular junction GO:0051124 2 0.025
nucleobase containing compound metabolic process GO:0006139 274 0.025
regulation of receptor activity GO:0010469 2 0.025
system process GO:0003008 185 0.025
axonogenesis GO:0007409 152 0.025
regulation of blood pressure GO:0008217 1 0.025
leukocyte proliferation GO:0070661 1 0.025
synaptic transmission GO:0007268 35 0.025
gene expression GO:0010467 252 0.024
inner ear morphogenesis GO:0042472 63 0.024
cellular component biogenesis GO:0044085 178 0.024
Mouse
cellular response to chemical stimulus GO:0070887 157 0.024
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.024
Zebrafish
lymphocyte proliferation GO:0046651 1 0.024
neuromuscular synaptic transmission GO:0007274 2 0.024
positive regulation of cellular component biogenesis GO:0044089 3 0.024
positive regulation of cellular process GO:0048522 201 0.023
negative regulation of metabolic process GO:0009892 86 0.023
cell projection organization GO:0030030 284 0.023
regulation of transporter activity GO:0032409 2 0.023
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.023
central nervous system development GO:0007417 387 0.023
Zebrafish
single organism transport GO:0044765 206 0.023
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.023
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.023
regulation of transmembrane transporter activity GO:0022898 2 0.023
embryonic neurocranium morphogenesis GO:0048702 15 0.022
regulation of circadian rhythm GO:0042752 4 0.022
cellular localization GO:0051641 97 0.022
limb bud formation GO:0060174 2 0.022
locomotion GO:0040011 313 0.022
Zebrafish
mesenchyme development GO:0060485 127 0.021
response to abiotic stimulus GO:0009628 122 0.021
sensory perception of chemical stimulus GO:0007606 3 0.021
actin filament based process GO:0030029 64 0.021
multicellular organism growth GO:0035264 4 0.021
tissue homeostasis GO:0001894 25 0.021
pancreatic a cell development GO:0003322 2 0.020
regulation of rna metabolic process GO:0051252 224 0.020
Zebrafish
endochondral bone growth GO:0003416 2 0.020
startle response GO:0001964 4 0.020
cell projection morphogenesis GO:0048858 244 0.020
hepatic duct development GO:0061011 2 0.020
cellular response to endogenous stimulus GO:0071495 68 0.020
regulation of biological quality GO:0065008 263 0.020
regulation of cellular response to growth factor stimulus GO:0090287 35 0.020
positive regulation of multicellular organismal process GO:0051240 52 0.020
oxidation reduction process GO:0055114 41 0.020
neuron projection extension GO:1990138 45 0.020
positive regulation of macromolecule metabolic process GO:0010604 93 0.020
rna biosynthetic process GO:0032774 181 0.020
response to uv GO:0009411 3 0.020
hepatocyte proliferation GO:0072574 2 0.020
skeletal system morphogenesis GO:0048705 102 0.020
embryonic heart tube development GO:0035050 133 0.019
Zebrafish
epidermis development GO:0008544 48 0.019
regulation of cell motility GO:2000145 46 0.019
negative regulation of cellular component movement GO:0051271 18 0.019
camera type eye development GO:0043010 222 0.019
cell adhesion GO:0007155 40 0.019
regulation of sodium ion transmembrane transport GO:1902305 1 0.019
connective tissue development GO:0061448 99 0.019
blood vessel morphogenesis GO:0048514 216 0.019
nephron morphogenesis GO:0072028 2 0.019
small molecule metabolic process GO:0044281 77 0.019
regulation of cytokine production GO:0001817 3 0.018
regulation of signaling GO:0023051 235 0.018
Zebrafish
protein complex subunit organization GO:0071822 46 0.018
regulation of protein transport GO:0051223 3 0.018
oocyte maturation GO:0001556 4 0.018
response to alkaloid GO:0043279 2 0.018
chemical homeostasis GO:0048878 49 0.018
regulation of protein complex assembly GO:0043254 3 0.018
axon extension GO:0048675 45 0.018
growth plate cartilage development GO:0003417 2 0.018
regulation of signal transduction GO:0009966 225 0.018
Zebrafish
mesenchymal cell proliferation GO:0010463 1 0.018
cartilage morphogenesis GO:0060536 13 0.017
ion homeostasis GO:0050801 41 0.017
divalent inorganic cation homeostasis GO:0072507 22 0.017
cellular response to nutrient levels GO:0031669 2 0.017
regulation of establishment of protein localization GO:0070201 4 0.017
regulation of metal ion transport GO:0010959 4 0.017
single organism metabolic process GO:0044710 217 0.017
Mouse
sensory system development GO:0048880 76 0.017
head development GO:0060322 303 0.017
Zebrafish
cellular component assembly involved in morphogenesis GO:0010927 107 0.017
positive regulation of map kinase activity GO:0043406 3 0.017
chloride transmembrane transport GO:1902476 4 0.017
regulation of molecular function GO:0065009 70 0.017
endoderm development GO:0007492 49 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
embryonic organ development GO:0048568 381 0.016
Zebrafish
macromolecule biosynthetic process GO:0009059 227 0.016
Mouse
purine ribonucleotide metabolic process GO:0009150 27 0.016
response to nicotine GO:0035094 2 0.016
negative regulation of gene expression GO:0010629 65 0.016
calcium ion homeostasis GO:0055074 19 0.016
androgen metabolic process GO:0008209 2 0.016
angiogenesis GO:0001525 158 0.016
cellular cation homeostasis GO:0030003 17 0.016
cellular calcium ion homeostasis GO:0006874 13 0.016
spinal cord anterior posterior patterning GO:0021512 1 0.016
chloride transport GO:0006821 8 0.016
positive regulation of biological process GO:0048518 253 0.016
negative regulation of macromolecule metabolic process GO:0010605 76 0.016
positive regulation of secretion GO:0051047 1 0.015
regulation of mesenchymal cell proliferation GO:0010464 1 0.015
cartilage development GO:0051216 96 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.015
Zebrafish
circadian sleep wake cycle process GO:0022410 2 0.015
protein secretion GO:0009306 1 0.015
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.015
cognition GO:0050890 1 0.015
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
regulation of collagen metabolic process GO:0010712 2 0.015
negative regulation of blood circulation GO:1903523 2 0.015
organic cyclic compound biosynthetic process GO:1901362 223 0.015
regulation of multicellular organism growth GO:0040014 4 0.015
regulation of circadian sleep wake cycle GO:0042749 1 0.015
neural crest cell differentiation GO:0014033 72 0.015
positive regulation of epithelial cell differentiation GO:0030858 2 0.015
developmental growth involved in morphogenesis GO:0060560 86 0.015
ribonucleotide metabolic process GO:0009259 27 0.015
organelle assembly GO:0070925 110 0.015
signal transduction in absence of ligand GO:0038034 1 0.015
carbohydrate derivative metabolic process GO:1901135 61 0.015
Mouse
regulation of cell cycle GO:0051726 52 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
glucose homeostasis GO:0042593 1 0.014
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.014
endochondral bone morphogenesis GO:0060350 8 0.014
cyclic purine nucleotide metabolic process GO:0052652 18 0.014
ameboidal type cell migration GO:0001667 143 0.014
Zebrafish
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.014
transcription dna templated GO:0006351 181 0.014
optic placode formation involved in camera type eye formation GO:0046619 3 0.014
bone remodeling GO:0046849 2 0.014
generation of neurons GO:0048699 385 0.014
cell cell signaling GO:0007267 52 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
cellular metal ion homeostasis GO:0006875 16 0.014
rna metabolic process GO:0016070 219 0.014
chondrocyte development GO:0002063 4 0.014
sensory organ morphogenesis GO:0090596 200 0.014
regulation of cell activation GO:0050865 1 0.014
segment polarity determination GO:0007367 1 0.014
wnt signaling pathway GO:0016055 80 0.013
embryonic skeletal joint development GO:0072498 3 0.013
wnt signaling pathway involved in dorsal ventral axis specification GO:0044332 5 0.013
apoptotic process GO:0006915 116 0.013
female gonad development GO:0008585 4 0.013
cellular response to organic substance GO:0071310 105 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
adult behavior GO:0030534 2 0.013
skin development GO:0043588 54 0.013
negative regulation of cell differentiation GO:0045596 46 0.013
cellular divalent inorganic cation homeostasis GO:0072503 13 0.013
developmental cell growth GO:0048588 52 0.013
regulation of localization GO:0032879 104 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
axon development GO:0061564 166 0.013
g2 m transition of mitotic cell cycle GO:0000086 4 0.013
cyclic nucleotide metabolic process GO:0009187 18 0.013
regulation of cell growth GO:0001558 29 0.013
cellular macromolecule biosynthetic process GO:0034645 224 0.013
Mouse
wound healing GO:0042060 90 0.013
otic vesicle development GO:0071599 42 0.013
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.013
cellular response to growth factor stimulus GO:0071363 39 0.013
regulation of protein catabolic process GO:0042176 1 0.013
tube morphogenesis GO:0035239 349 0.012
Zebrafish
cellular response to organic cyclic compound GO:0071407 38 0.012
death GO:0016265 121 0.012
intracellular estrogen receptor signaling pathway GO:0030520 3 0.012
negative regulation of apoptotic process GO:0043066 55 0.012
lateral line system development GO:0048925 76 0.012
regulation of bone mineralization GO:0030500 2 0.012
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.012
tissue regeneration GO:0042246 74 0.012
trabecula formation GO:0060343 2 0.012
transmembrane transport GO:0055085 120 0.012
optic placode formation GO:0001743 4 0.012
single organism nuclear import GO:1902593 3 0.012
cellular homeostasis GO:0019725 26 0.012
cellular ion homeostasis GO:0006873 17 0.012
single organism organelle organization GO:1902589 199 0.012
meiotic nuclear division GO:0007126 4 0.012
heart process GO:0003015 71 0.011
regulation of phosphate metabolic process GO:0019220 43 0.011
compound eye development GO:0048749 2 0.011
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:0042771 2 0.011
convergent extension involved in organogenesis GO:0060029 10 0.011
phagocytosis GO:0006909 3 0.011
embryonic digestive tract development GO:0048566 4 0.011
organ formation GO:0048645 17 0.011
protein polymerization GO:0051258 4 0.011
response to hydrogen peroxide GO:0042542 3 0.011
behavior GO:0007610 74 0.011
otic vesicle morphogenesis GO:0071600 34 0.011
inorganic anion transport GO:0015698 25 0.011
mediolateral intercalation GO:0060031 3 0.011
embryonic pattern specification GO:0009880 44 0.011
negative regulation of cell migration GO:0030336 17 0.011
regulation of primary metabolic process GO:0080090 311 0.011
Zebrafish
digestive tract morphogenesis GO:0048546 231 0.011
Zebrafish
rostrocaudal neural tube patterning GO:0021903 29 0.011
regulation of developmental process GO:0050793 247 0.011
Zebrafish
regulation of nucleic acid templated transcription GO:1903506 213 0.010
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.010
regulation of catalytic activity GO:0050790 55 0.010
response to wounding GO:0009611 116 0.010
protein localization to nucleus GO:0034504 3 0.010
leukocyte differentiation GO:0002521 25 0.010
small gtpase mediated signal transduction GO:0007264 8 0.010
purine containing compound metabolic process GO:0072521 29 0.010
regulation of cellular component movement GO:0051270 55 0.010
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.010
heart formation GO:0060914 13 0.010
outflow tract morphogenesis GO:0003151 1 0.010
regulation of cell death GO:0010941 103 0.010
proximal distal pattern formation GO:0009954 1 0.010

has3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.088
disease of anatomical entity DOID:7 0 0.088
eye and adnexa disease DOID:1492 0 0.088
nervous system disease DOID:863 0 0.088
eye disease DOID:5614 0 0.088
osteochondrodysplasia DOID:2256 0 0.039
bone development disease DOID:0080006 0 0.039
bone disease DOID:0080001 0 0.039
musculoskeletal system disease DOID:17 0 0.039
connective tissue disease DOID:65 0 0.039
retinal disease DOID:5679 0 0.018
disease of mental health DOID:150 0 0.010
developmental disorder of mental health DOID:0060037 0 0.010