Danio rerio

0 known processes

otof

otoferlin

(Aliases: wu:fj34b10,si:dkey-181f18.3,fj34b10)

otof biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ development GO:0007423 393 0.210
neuron differentiation GO:0030182 353 0.155
multicellular organism growth GO:0035264 4 0.129
regulation of multicellular organism growth GO:0040014 4 0.121
larval development GO:0002164 2 0.112
neuron development GO:0048666 262 0.110
cell morphogenesis GO:0000902 289 0.105
eye photoreceptor cell development GO:0042462 30 0.101
membrane fusion GO:0061025 2 0.089
generation of neurons GO:0048699 385 0.088
ear development GO:0043583 127 0.083
cilium organization GO:0044782 71 0.082
cell projection organization GO:0030030 284 0.081
inner ear receptor cell differentiation GO:0060113 29 0.080
inner ear receptor cell development GO:0060119 20 0.069
sensory organ morphogenesis GO:0090596 200 0.068
negative regulation of biological process GO:0048519 304 0.063
regulation of cell shape GO:0008360 1 0.061
locomotion GO:0040011 313 0.061
inner ear development GO:0048839 126 0.060
lateral line development GO:0048882 66 0.057
eye development GO:0001654 277 0.056
single organism membrane fusion GO:0044801 2 0.055
regulation of reproductive process GO:2000241 4 0.054
neuromuscular process controlling balance GO:0050885 3 0.053
lateral line system development GO:0048925 76 0.052
regulation of multicellular organismal process GO:0051239 277 0.051
cell migration GO:0016477 237 0.049
response to external stimulus GO:0009605 264 0.046
cellular component movement GO:0006928 335 0.045
otolith development GO:0048840 32 0.045
regulation of protein complex assembly GO:0043254 3 0.043
single organism localization GO:1902578 225 0.042
Mouse
eye morphogenesis GO:0048592 144 0.041
developmental growth GO:0048589 166 0.041
negative regulation of reproductive process GO:2000242 3 0.038
camera type eye photoreceptor cell differentiation GO:0060219 19 0.037
neural retina development GO:0003407 49 0.036
organelle fusion GO:0048284 3 0.036
multi organism process GO:0051704 134 0.035
exocytosis GO:0006887 1 0.035
Mouse
eye photoreceptor cell differentiation GO:0001754 45 0.035
aging GO:0007568 2 0.033
regulation of localization GO:0032879 104 0.032
hemopoiesis GO:0030097 183 0.032
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.032
synaptic vesicle localization GO:0097479 1 0.031
Mouse
axoneme assembly GO:0035082 9 0.031
regeneration GO:0031099 91 0.031
regulation of locomotion GO:0040012 55 0.030
tissue regeneration GO:0042246 74 0.030
regulation of intracellular ph GO:0051453 1 0.030
actin filament based movement GO:0030048 1 0.029
compound eye development GO:0048749 2 0.028
regulation of response to cytokine stimulus GO:0060759 3 0.028
immune system process GO:0002376 241 0.028
morphogenesis of an epithelium GO:0002009 333 0.028
protein import into nucleus GO:0006606 3 0.028
response to stress GO:0006950 263 0.027
cellular response to light stimulus GO:0071482 4 0.027
cell motility GO:0048870 244 0.026
axon development GO:0061564 166 0.026
synaptic growth at neuromuscular junction GO:0051124 2 0.026
phagocytosis GO:0006909 3 0.026
maintenance of location GO:0051235 4 0.025
positive regulation of protein complex assembly GO:0031334 2 0.025
regulation of neurogenesis GO:0050767 87 0.025
antimicrobial humoral response GO:0019730 2 0.025
cellular component disassembly GO:0022411 1 0.025
microtubule based movement GO:0007018 33 0.024
photoreceptor cell development GO:0042461 40 0.024
endosomal transport GO:0016197 2 0.024
cell part morphogenesis GO:0032990 246 0.023
regulation of synapse assembly GO:0051963 3 0.023
posterior lateral line development GO:0048916 38 0.023
retina development in camera type eye GO:0060041 146 0.023
hematopoietic or lymphoid organ development GO:0048534 191 0.023
regulation of biological quality GO:0065008 263 0.022
Mouse
actin polymerization or depolymerization GO:0008154 2 0.022
regulation of ion transmembrane transporter activity GO:0032412 2 0.022
cell morphogenesis involved in differentiation GO:0000904 195 0.022
regulation of synapse organization GO:0050807 3 0.022
cellular response to molecule of bacterial origin GO:0071219 3 0.022
signal transduction GO:0007165 455 0.022
regulation of protein polymerization GO:0032271 2 0.021
cellular response to extracellular stimulus GO:0031668 2 0.021
negative regulation of cellular process GO:0048523 283 0.021
lipid storage GO:0019915 1 0.021
negative regulation of sequestering of calcium ion GO:0051283 4 0.021
cellular component assembly involved in morphogenesis GO:0010927 107 0.021
positive regulation of catabolic process GO:0009896 4 0.021
regulation of developmental process GO:0050793 247 0.020
localization of cell GO:0051674 244 0.020
posterior lateral line system development GO:0048915 46 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
ion transport GO:0006811 114 0.020
regulation of cell migration GO:0030334 40 0.020
retina morphogenesis in camera type eye GO:0060042 79 0.020
photoreceptor cell differentiation GO:0046530 55 0.020
neuron projection development GO:0031175 180 0.020
neuromast development GO:0048884 46 0.020
neuron neuron synaptic transmission GO:0007270 1 0.020
neuron projection regeneration GO:0031102 16 0.020
heart development GO:0007507 313 0.019
immune system development GO:0002520 191 0.019
sequestering of calcium ion GO:0051208 3 0.019
cellular component assembly GO:0022607 170 0.019
neurotransmitter transport GO:0006836 2 0.019
Mouse
positive regulation of protein polymerization GO:0032273 2 0.018
liver development GO:0001889 96 0.018
cilium movement GO:0003341 26 0.018
ion transmembrane transport GO:0034220 91 0.018
reflex GO:0060004 2 0.018
regulation of sequestering of calcium ion GO:0051282 4 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.018
regulation of cellular component movement GO:0051270 55 0.018
protein localization to nucleus GO:0034504 3 0.018
homeostatic process GO:0042592 142 0.018
retinal cone cell development GO:0046549 8 0.018
protein metabolic process GO:0019538 183 0.018
mechanoreceptor differentiation GO:0042490 37 0.018
erythrocyte homeostasis GO:0034101 55 0.018
gland development GO:0048732 143 0.017
establishment of organelle localization GO:0051656 45 0.017
Mouse
fin regeneration GO:0031101 51 0.017
synaptic vesicle recycling GO:0036465 1 0.017
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.017
single organism transport GO:0044765 206 0.017
Mouse
response to biotic stimulus GO:0009607 97 0.017
purine nucleoside monophosphate catabolic process GO:0009128 4 0.017
organelle assembly GO:0070925 110 0.017
single organism biosynthetic process GO:0044711 71 0.017
protein polymerization GO:0051258 4 0.017
inorganic ion transmembrane transport GO:0098660 57 0.017
camera type eye morphogenesis GO:0048593 108 0.017
single organism metabolic process GO:0044710 217 0.017
mitochondrion organization GO:0007005 4 0.017
single organism organelle organization GO:1902589 199 0.017
microtubule bundle formation GO:0001578 9 0.017
aromatic compound biosynthetic process GO:0019438 217 0.017
cellular macromolecule metabolic process GO:0044260 391 0.016
cilium assembly GO:0042384 58 0.016
response to ketone GO:1901654 1 0.016
positive regulation of transport GO:0051050 2 0.016
inner ear receptor stereocilium organization GO:0060122 8 0.016
cellular biosynthetic process GO:0044249 286 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.016
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
establishment of localization GO:0051234 244 0.016
Mouse
autophagy GO:0006914 4 0.016
neuromast deposition GO:0048885 9 0.016
sensory system development GO:0048880 76 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
embryonic skeletal system morphogenesis GO:0048704 93 0.016
mechanosensory lateral line system development GO:0048881 49 0.016
hepaticobiliary system development GO:0061008 98 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
stem cell proliferation GO:0072089 4 0.015
sequestering of metal ion GO:0051238 3 0.015
embryonic skeletal system development GO:0048706 97 0.015
nuclear transport GO:0051169 4 0.015
camera type eye development GO:0043010 222 0.015
regulation of metabolic process GO:0019222 359 0.015
small molecule metabolic process GO:0044281 77 0.015
microtubule cytoskeleton organization GO:0000226 33 0.015
organelle organization GO:0006996 227 0.015
stem cell maintenance GO:0019827 4 0.015
response to other organism GO:0051707 97 0.015
regulation of macromolecule biosynthetic process GO:0010556 225 0.015
chemotaxis GO:0006935 104 0.015
regulation of cell motility GO:2000145 46 0.014
tissue remodeling GO:0048771 4 0.014
axonogenesis GO:0007409 152 0.014
otic vesicle development GO:0071599 42 0.014
homeostasis of number of cells GO:0048872 62 0.014
regulation of gtpase activity GO:0043087 2 0.014
gtp metabolic process GO:0046039 4 0.014
response to wounding GO:0009611 116 0.014
protein targeting to nucleus GO:0044744 3 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
organic substance biosynthetic process GO:1901576 289 0.014
tube morphogenesis GO:0035239 349 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
central nervous system development GO:0007417 387 0.014
cellular pigmentation GO:0033059 30 0.014
ameboidal type cell migration GO:0001667 143 0.014
regulation of organ growth GO:0046620 3 0.014
regulation of circadian rhythm GO:0042752 4 0.014
regulation of cell development GO:0060284 100 0.013
synaptic vesicle endocytosis GO:0048488 1 0.013
cellular protein metabolic process GO:0044267 129 0.013
nuclear import GO:0051170 3 0.013
startle response GO:0001964 4 0.013
regulation of transporter activity GO:0032409 2 0.013
negative regulation of multicellular organismal process GO:0051241 69 0.013
skeletal system development GO:0001501 181 0.013
protein import GO:0017038 3 0.013
cellular response to nutrient levels GO:0031669 2 0.013
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.013
equilibrioception GO:0050957 2 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
system process GO:0003008 185 0.013
reactive oxygen species metabolic process GO:0072593 6 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
myeloid cell differentiation GO:0030099 86 0.013
regulation of signal transduction GO:0009966 225 0.013
vestibular reflex GO:0060005 2 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
regulation of metal ion transport GO:0010959 4 0.013
epithelial cell morphogenesis GO:0003382 2 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
brain development GO:0007420 293 0.012
regulation of binding GO:0051098 3 0.012
mitochondrial transport GO:0006839 2 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
pancreas development GO:0031016 84 0.012
cellular response to starvation GO:0009267 1 0.012
synaptic vesicle transport GO:0048489 1 0.012
Mouse
response to external biotic stimulus GO:0043207 97 0.012
organelle localization GO:0051640 49 0.012
Mouse
membrane hyperpolarization GO:0060081 1 0.012
cellular response to external stimulus GO:0071496 2 0.012
single organism nuclear import GO:1902593 3 0.012
head development GO:0060322 303 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
regulation of calcium ion transport GO:0051924 2 0.012
macroautophagy GO:0016236 1 0.012
positive regulation of secretion GO:0051047 1 0.012
membrane organization GO:0061024 21 0.012
establishment of protein localization to organelle GO:0072594 4 0.012
embryonic hemopoiesis GO:0035162 53 0.012
neuron projection guidance GO:0097485 86 0.012
vasculature development GO:0001944 278 0.012
macromolecular complex disassembly GO:0032984 1 0.012
biosynthetic process GO:0009058 294 0.012
organic acid metabolic process GO:0006082 31 0.012
muscle structure development GO:0061061 196 0.012
golgi vesicle transport GO:0048193 3 0.011
regulation of protein transport GO:0051223 3 0.011
negative regulation of synapse assembly GO:0051964 2 0.011
erythrocyte differentiation GO:0030218 54 0.011
stem cell differentiation GO:0048863 117 0.011
protein targeting to membrane GO:0006612 1 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
cellular ketone metabolic process GO:0042180 11 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
cation transmembrane transport GO:0098655 65 0.011
cellular protein complex disassembly GO:0043624 1 0.011
regulation of cellular ph GO:0030641 1 0.011
heart process GO:0003015 71 0.011
rna localization GO:0006403 4 0.011
melanin metabolic process GO:0006582 2 0.011
protein localization to plasma membrane GO:0072659 1 0.011
post golgi vesicle mediated transport GO:0006892 1 0.011
melanosome localization GO:0032400 21 0.011
regulation of striated muscle contraction GO:0006942 2 0.011
atp catabolic process GO:0006200 4 0.011
cell projection assembly GO:0030031 64 0.011
growth GO:0040007 174 0.011
protein complex disassembly GO:0043241 1 0.011
positive regulation of cell cycle GO:0045787 3 0.011
negative regulation of multi organism process GO:0043901 3 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
Mouse
regulation of neuron migration GO:2001222 2 0.011
glucose homeostasis GO:0042593 1 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.010
digestive system development GO:0055123 289 0.010
lamellipodium assembly GO:0030032 1 0.010
regulation of muscle contraction GO:0006937 3 0.010
cellular amine metabolic process GO:0044106 2 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010
tissue migration GO:0090130 37 0.010
heterocycle biosynthetic process GO:0018130 215 0.010
adult behavior GO:0030534 2 0.010
nucleocytoplasmic transport GO:0006913 4 0.010
regulation of protein complex disassembly GO:0043244 1 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
regulation of synaptic vesicle transport GO:1902803 1 0.010

otof disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.036
disease of anatomical entity DOID:7 0 0.036
Human
hematopoietic system disease DOID:74 0 0.022
nervous system disease DOID:863 0 0.011
Human