Danio rerio

0 known processes

mc1r

melanocortin 1 receptor

mc1r biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
energy homeostasis GO:0097009 3 0.890
Zebrafish
positive regulation of camp biosynthetic process GO:0030819 2 0.761
Zebrafish
single organism biosynthetic process GO:0044711 71 0.733
Zebrafish Mouse
regulation of cyclic nucleotide biosynthetic process GO:0030802 15 0.701
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.676
Zebrafish Mouse
organic substance biosynthetic process GO:1901576 289 0.671
Zebrafish Mouse
positive regulation of purine nucleotide biosynthetic process GO:1900373 8 0.649
Zebrafish
positive regulation of camp metabolic process GO:0030816 2 0.631
Zebrafish
signal transduction GO:0007165 455 0.602
Zebrafish Mouse
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.571
Zebrafish
ribonucleotide biosynthetic process GO:0009260 20 0.565
Zebrafish
regulation of metabolic process GO:0019222 359 0.503
Zebrafish Mouse
phosphorus metabolic process GO:0006793 109 0.497
Zebrafish
energy reserve metabolic process GO:0006112 2 0.477
Zebrafish
regulation of camp biosynthetic process GO:0030817 9 0.463
Zebrafish
negative regulation of feeding behavior GO:2000252 2 0.458
Zebrafish
cellular biosynthetic process GO:0044249 286 0.454
Zebrafish Mouse
nitrogen compound metabolic process GO:0006807 319 0.403
Zebrafish Mouse
regulation of biosynthetic process GO:0009889 250 0.378
Zebrafish Mouse
organonitrogen compound metabolic process GO:1901564 74 0.361
Zebrafish
homeostatic process GO:0042592 142 0.349
Zebrafish
positive regulation of nucleotide biosynthetic process GO:0030810 8 0.342
Zebrafish
camp biosynthetic process GO:0006171 11 0.340
Zebrafish
single organism metabolic process GO:0044710 217 0.337
Zebrafish Mouse
purine nucleotide biosynthetic process GO:0006164 20 0.336
Zebrafish
regulation of cellular metabolic process GO:0031323 320 0.329
Zebrafish Mouse
g protein coupled receptor signaling pathway GO:0007186 74 0.310
Zebrafish Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.303
purine containing compound biosynthetic process GO:0072522 20 0.297
Zebrafish
aging GO:0007568 2 0.292
neuron projection development GO:0031175 180 0.289
camp metabolic process GO:0046058 11 0.288
Zebrafish
cognition GO:0050890 1 0.278
regulation of nucleotide biosynthetic process GO:0030808 15 0.271
Zebrafish
cyclic purine nucleotide metabolic process GO:0052652 18 0.267
Zebrafish
regulation of nucleotide metabolic process GO:0006140 17 0.265
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.251
Zebrafish Mouse
small molecule metabolic process GO:0044281 77 0.250
Zebrafish
aromatic compound biosynthetic process GO:0019438 217 0.243
Zebrafish Mouse
cyclic nucleotide metabolic process GO:0009187 18 0.239
Zebrafish
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.238
Zebrafish
regulation of response to stimulus GO:0048583 269 0.235
Zebrafish Mouse
regulation of camp metabolic process GO:0030814 9 0.220
Zebrafish
purine containing compound metabolic process GO:0072521 29 0.219
Zebrafish
heterocycle biosynthetic process GO:0018130 215 0.218
Zebrafish Mouse
cellular ketone metabolic process GO:0042180 11 0.215
biosynthetic process GO:0009058 294 0.211
Zebrafish Mouse
nucleoside phosphate metabolic process GO:0006753 28 0.204
Zebrafish
axon development GO:0061564 166 0.194
negative regulation of biological process GO:0048519 304 0.189
Zebrafish
ribonucleotide metabolic process GO:0009259 27 0.187
Zebrafish
amine metabolic process GO:0009308 2 0.180
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.178
Zebrafish Mouse
metal ion homeostasis GO:0055065 26 0.174
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.164
single organismal cell cell adhesion GO:0016337 29 0.163
regulation of nitrogen compound metabolic process GO:0051171 251 0.161
Zebrafish Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.159
Zebrafish Mouse
organic cyclic compound metabolic process GO:1901360 301 0.159
Zebrafish Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.158
Zebrafish Mouse
heterocycle metabolic process GO:0046483 290 0.154
Zebrafish Mouse
generation of neurons GO:0048699 385 0.150
behavior GO:0007610 74 0.149
Zebrafish
cellular aromatic compound metabolic process GO:0006725 295 0.149
Zebrafish Mouse
regulation of biological quality GO:0065008 263 0.148
Zebrafish
sensory perception of chemical stimulus GO:0007606 3 0.146
cellular component morphogenesis GO:0032989 336 0.145
cellular component movement GO:0006928 335 0.142
ribose phosphate metabolic process GO:0019693 27 0.142
Zebrafish
cell projection morphogenesis GO:0048858 244 0.141
cell part morphogenesis GO:0032990 246 0.141
positive regulation of cellular process GO:0048522 201 0.138
Zebrafish Mouse
locomotion GO:0040011 313 0.137
positive regulation of cellular metabolic process GO:0031325 94 0.135
Zebrafish Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.134
Zebrafish Mouse
cell surface receptor signaling pathway GO:0007166 325 0.132
Zebrafish Mouse
neuron differentiation GO:0030182 353 0.130
vasculature development GO:0001944 278 0.130
regulation of rna metabolic process GO:0051252 224 0.122
Mouse
purine ribonucleotide biosynthetic process GO:0009152 20 0.120
Zebrafish
divalent inorganic cation homeostasis GO:0072507 22 0.120
tissue remodeling GO:0048771 4 0.119
chemical homeostasis GO:0048878 49 0.117
multicellular organismal homeostasis GO:0048871 29 0.116
Zebrafish
striated muscle tissue development GO:0014706 110 0.114
cell migration GO:0016477 237 0.114
muscle structure development GO:0061061 196 0.114
cellular amine metabolic process GO:0044106 2 0.114
cellular component assembly GO:0022607 170 0.112
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 8 0.110
Zebrafish
nucleotide biosynthetic process GO:0009165 21 0.108
Zebrafish
regulation of cell communication GO:0010646 232 0.108
Mouse
cell morphogenesis GO:0000902 289 0.107
organophosphate biosynthetic process GO:0090407 23 0.107
Zebrafish
periodic partitioning GO:0007365 1 0.106
cation homeostasis GO:0055080 33 0.106
nucleoside phosphate biosynthetic process GO:1901293 21 0.104
Zebrafish
maintenance of location GO:0051235 4 0.103
hindbrain development GO:0030902 91 0.102
biological adhesion GO:0022610 40 0.102
regulation of cellular amine metabolic process GO:0033238 0 0.100
regulation of systemic arterial blood pressure GO:0003073 1 0.097
regulation of jak stat cascade GO:0046425 3 0.096
phosphate containing compound metabolic process GO:0006796 108 0.096
Zebrafish
regulation of sequestering of calcium ion GO:0051282 4 0.093
regulation of developmental process GO:0050793 247 0.093
purine nucleotide metabolic process GO:0006163 27 0.089
Zebrafish
regulation of blood pressure GO:0008217 1 0.089
nucleobase containing compound biosynthetic process GO:0034654 205 0.089
Zebrafish Mouse
sequestering of calcium ion GO:0051208 3 0.088
brain development GO:0007420 293 0.086
synaptic growth at neuromuscular junction GO:0051124 2 0.086
determination of left right symmetry GO:0007368 179 0.085
purine ribonucleotide metabolic process GO:0009150 27 0.082
Zebrafish
cell adhesion GO:0007155 40 0.081
cellular calcium ion homeostasis GO:0006874 13 0.079
cell morphogenesis involved in differentiation GO:0000904 195 0.079
tube morphogenesis GO:0035239 349 0.079
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.078
Zebrafish Mouse
oxidation reduction process GO:0055114 41 0.077
Zebrafish
regulation of purine nucleotide metabolic process GO:1900542 17 0.076
Zebrafish
determination of bilateral symmetry GO:0009855 204 0.076
neuron development GO:0048666 262 0.075
sequestering of metal ion GO:0051238 3 0.075
immune system process GO:0002376 241 0.075
cellular response to external stimulus GO:0071496 2 0.074
cellular macromolecule metabolic process GO:0044260 391 0.071
Mouse
regulation of phosphate metabolic process GO:0019220 43 0.071
Zebrafish
negative regulation of cellular process GO:0048523 283 0.070
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.069
Mouse
response to organic substance GO:0010033 153 0.069
regulation of phosphorus metabolic process GO:0051174 43 0.069
Zebrafish
organonitrogen compound biosynthetic process GO:1901566 47 0.068
Zebrafish
positive regulation of cyclic nucleotide metabolic process GO:0030801 8 0.068
Zebrafish
regulation of primary metabolic process GO:0080090 311 0.067
Zebrafish Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.067
single organism organelle organization GO:1902589 199 0.066
regulation of multicellular organismal process GO:0051239 277 0.065
regulation of signal transduction GO:0009966 225 0.064
Mouse
nucleotide metabolic process GO:0009117 28 0.064
Zebrafish
cyclic nucleotide biosynthetic process GO:0009190 18 0.064
Zebrafish
sensory perception of smell GO:0007608 2 0.063
regulation of cellular ketone metabolic process GO:0010565 7 0.063
calcium ion homeostasis GO:0055074 19 0.063
regulation of macromolecule metabolic process GO:0060255 317 0.062
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.060
larval development GO:0002164 2 0.060
apoptotic process involved in morphogenesis GO:0060561 2 0.058
alcohol biosynthetic process GO:0046165 2 0.056
positive regulation of signaling GO:0023056 56 0.056
Mouse
nucleic acid metabolic process GO:0090304 244 0.055
Mouse
response to chemical GO:0042221 320 0.054
cell projection organization GO:0030030 284 0.054
negative regulation of sequestering of calcium ion GO:0051283 4 0.053
microtubule based process GO:0007017 60 0.053
intracellular signal transduction GO:0035556 85 0.053
Mouse
ion homeostasis GO:0050801 41 0.052
positive regulation of biological process GO:0048518 253 0.052
Zebrafish Mouse
taxis GO:0042330 109 0.051
regulation of establishment of protein localization GO:0070201 4 0.051
neuron projection morphogenesis GO:0048812 161 0.051
regulation of cell death GO:0010941 103 0.050
regulation of nucleic acid templated transcription GO:1903506 213 0.048
Mouse
adult behavior GO:0030534 2 0.047
developmental growth involved in morphogenesis GO:0060560 86 0.047
muscle cell differentiation GO:0042692 139 0.046
cellular component biogenesis GO:0044085 178 0.046
axonogenesis GO:0007409 152 0.045
transcription from rna polymerase ii promoter GO:0006366 80 0.045
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.045
Zebrafish Mouse
positive regulation of neural precursor cell proliferation GO:2000179 1 0.045
developmental growth GO:0048589 166 0.045
specification of symmetry GO:0009799 204 0.044
carbohydrate derivative biosynthetic process GO:1901137 43 0.044
Zebrafish
positive regulation of metabolic process GO:0009893 108 0.043
Zebrafish Mouse
rna metabolic process GO:0016070 219 0.043
Mouse
response to external stimulus GO:0009605 264 0.043
embryonic organ morphogenesis GO:0048562 274 0.043
neuropeptide signaling pathway GO:0007218 11 0.042
Zebrafish
head development GO:0060322 303 0.042
positive regulation of rna biosynthetic process GO:1902680 57 0.042
Mouse
positive regulation of programmed cell death GO:0043068 29 0.042
cell fate commitment GO:0045165 99 0.041
gene expression GO:0010467 252 0.040
Mouse
nucleic acid templated transcription GO:0097659 181 0.040
Mouse
gland development GO:0048732 143 0.040
Zebrafish
cellular response to lipid GO:0071396 39 0.039
organophosphate metabolic process GO:0019637 37 0.039
Zebrafish
sensory perception GO:0007600 39 0.039
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 1 0.039
cellular nitrogen compound biosynthetic process GO:0044271 218 0.037
Zebrafish Mouse
chemosensory behavior GO:0007635 1 0.037
regulation of retina development in camera type eye GO:1902866 2 0.037
dicarboxylic acid metabolic process GO:0043648 1 0.037
morphogenesis of an epithelium GO:0002009 333 0.037
negative regulation of multicellular organismal process GO:0051241 69 0.037
regulation of cell differentiation GO:0045595 142 0.036
cellular amino acid metabolic process GO:0006520 7 0.036
positive regulation of protein complex assembly GO:0031334 2 0.036
female gonad development GO:0008585 4 0.036
ovulation cycle GO:0042698 2 0.036
regulation of multicellular organism growth GO:0040014 4 0.036
skeletal system development GO:0001501 181 0.036
lipid metabolic process GO:0006629 52 0.035
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.035
negative regulation of signaling GO:0023057 96 0.035
regulation of intracellular signal transduction GO:1902531 57 0.034
Mouse
hormone metabolic process GO:0042445 19 0.034
post embryonic organ development GO:0048569 4 0.034
macromolecule modification GO:0043412 111 0.034
phosphorylation GO:0016310 69 0.034
regulation of system process GO:0044057 40 0.033
organic acid metabolic process GO:0006082 31 0.033
antimicrobial humoral response GO:0019730 2 0.033
positive regulation of cellular component biogenesis GO:0044089 3 0.033
negative regulation of programmed cell death GO:0043069 58 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.032
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.032
Zebrafish
regulation of cellular protein metabolic process GO:0032268 52 0.032
ovulation cycle process GO:0022602 2 0.032
embryonic organ development GO:0048568 381 0.031
regulation of rna biosynthetic process GO:2001141 213 0.031
Mouse
chemotaxis GO:0006935 104 0.031
response to external biotic stimulus GO:0043207 97 0.031
circulatory system process GO:0003013 87 0.031
cell fate specification GO:0001708 68 0.031
negative regulation of cell communication GO:0010648 96 0.031
chordate embryonic development GO:0043009 271 0.030
positive regulation of cytokine production GO:0001819 2 0.030
cellular response to chemical stimulus GO:0070887 157 0.030
multicellular organism growth GO:0035264 4 0.030
growth GO:0040007 174 0.030
Zebrafish
axon guidance GO:0007411 86 0.030
endocrine system development GO:0035270 65 0.029
Zebrafish
multicellular organismal macromolecule metabolic process GO:0044259 2 0.029
protein modification process GO:0036211 100 0.029
single organism cell adhesion GO:0098602 29 0.029
gtp catabolic process GO:0006184 2 0.029
developmental programmed cell death GO:0010623 4 0.028
embryonic heart tube morphogenesis GO:0003143 108 0.028
energy derivation by oxidation of organic compounds GO:0015980 5 0.028
Zebrafish
axon extension GO:0048675 45 0.028
localization of cell GO:0051674 244 0.028
cellular response to extracellular stimulus GO:0031668 2 0.028
positive regulation of biosynthetic process GO:0009891 68 0.028
Zebrafish Mouse
response to oxygen containing compound GO:1901700 55 0.028
fat soluble vitamin biosynthetic process GO:0042362 2 0.028
system process GO:0003008 185 0.028
Mouse
negative regulation of response to stimulus GO:0048585 104 0.028
Zebrafish
macromolecule biosynthetic process GO:0009059 227 0.027
Mouse
positive regulation of macromolecule metabolic process GO:0010604 93 0.027
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.027
gtp metabolic process GO:0046039 4 0.027
response to bacterium GO:0009617 58 0.027
positive regulation of nucleic acid templated transcription GO:1903508 57 0.027
Mouse
osteoclast differentiation GO:0030316 1 0.026
organelle organization GO:0006996 227 0.026
venous blood vessel development GO:0060841 9 0.026
cardiac atrium morphogenesis GO:0003209 2 0.026
response to other organism GO:0051707 97 0.026
response to stress GO:0006950 263 0.026
regulation of signaling GO:0023051 235 0.026
Mouse
microtubule cytoskeleton organization GO:0000226 33 0.026
nucleobase containing small molecule metabolic process GO:0055086 32 0.026
Zebrafish
protein secretion GO:0009306 1 0.025
dopamine metabolic process GO:0042417 2 0.025
blood circulation GO:0008015 87 0.025
regulation of synapse organization GO:0050807 3 0.025
regulation of protein complex assembly GO:0043254 3 0.025
cellular hormone metabolic process GO:0034754 19 0.025
response to organic cyclic compound GO:0014070 51 0.025
muscle tissue development GO:0060537 110 0.025
cellular metal ion homeostasis GO:0006875 16 0.025
positive regulation of cellular amine metabolic process GO:0033240 0 0.024
secondary metabolic process GO:0019748 3 0.024
Mouse
cellular homeostasis GO:0019725 26 0.024
positive regulation of jak stat cascade GO:0046427 2 0.024
heart contraction GO:0060047 71 0.024
ribose phosphate biosynthetic process GO:0046390 20 0.024
Zebrafish
negative regulation of signal transduction GO:0009968 94 0.024
cellular response to molecule of bacterial origin GO:0071219 3 0.024
cellular response to radiation GO:0071478 4 0.024
enzyme linked receptor protein signaling pathway GO:0007167 106 0.024
regulation of blood circulation GO:1903522 32 0.023
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.023
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.023
regulation of protein transport GO:0051223 3 0.023
cation transport GO:0006812 81 0.023
cartilage development GO:0051216 96 0.023
kupffer s vesicle development GO:0070121 50 0.023
carboxylic acid metabolic process GO:0019752 22 0.023
mitochondrion organization GO:0007005 4 0.023
cellular protein modification process GO:0006464 100 0.022
positive regulation of multicellular organismal process GO:0051240 52 0.022
cell motility GO:0048870 244 0.022
regulation of circadian rhythm GO:0042752 4 0.022
phototransduction GO:0007602 2 0.022
neuron projection extension GO:1990138 45 0.022
cellular response to nutrient levels GO:0031669 2 0.021
negative regulation of stem cell differentiation GO:2000737 2 0.021
muscle cell development GO:0055001 115 0.021
stem cell maintenance GO:0019827 4 0.021
cellular response to starvation GO:0009267 1 0.021
regulation of catalytic activity GO:0050790 55 0.021
heart looping GO:0001947 94 0.021
b cell activation GO:0042113 2 0.021
cellular response to biotic stimulus GO:0071216 3 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.020
regulation of apoptotic process GO:0042981 98 0.020
cellular cation homeostasis GO:0030003 17 0.020
protein metabolic process GO:0019538 183 0.020
positive regulation of cell differentiation GO:0045597 30 0.020
embryonic limb morphogenesis GO:0030326 2 0.020
regulation of anatomical structure morphogenesis GO:0022603 130 0.020
apoptotic process involved in development GO:1902742 2 0.020
membrane repolarization GO:0086009 2 0.020
developmental cell growth GO:0048588 52 0.020
digestive tract development GO:0048565 265 0.020
cellular macromolecule biosynthetic process GO:0034645 224 0.020
Mouse
oxoacid metabolic process GO:0043436 31 0.019
exocytosis GO:0006887 1 0.019
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.019
stem cell differentiation GO:0048863 117 0.019
embryonic hemopoiesis GO:0035162 53 0.019
positive regulation of leukocyte mediated immunity GO:0002705 1 0.019
microtubule polymerization or depolymerization GO:0031109 3 0.019
guanosine containing compound metabolic process GO:1901068 4 0.019
regulation of multicellular organismal development GO:2000026 223 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.019
regulation of dendrite development GO:0050773 3 0.019
neurological system process GO:0050877 62 0.018
Mouse
embryonic heart tube development GO:0035050 133 0.018
myeloid cell differentiation GO:0030099 86 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.018
neuroblast proliferation GO:0007405 2 0.018
sensory perception of touch GO:0050975 2 0.018
response to endogenous stimulus GO:0009719 83 0.018
heart development GO:0007507 313 0.018
positive regulation of protein metabolic process GO:0051247 23 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.018
actin cytoskeleton organization GO:0030036 63 0.018
single organism behavior GO:0044708 24 0.018
cellular response to unfolded protein GO:0034620 2 0.018
cellular ion homeostasis GO:0006873 17 0.018
tissue homeostasis GO:0001894 25 0.018
striated muscle cell development GO:0055002 108 0.018
germ line stem cell maintenance GO:0030718 2 0.018
negative regulation of apoptotic process GO:0043066 55 0.018
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 5 0.017
programmed cell death GO:0012501 119 0.017
negative regulation of metabolic process GO:0009892 86 0.017
regulation of response to cytokine stimulus GO:0060759 3 0.017
response to xenobiotic stimulus GO:0009410 45 0.017
positive regulation of catabolic process GO:0009896 4 0.017
glucocorticoid metabolic process GO:0008211 2 0.017
synapse organization GO:0050808 21 0.017
guanosine containing compound catabolic process GO:1901069 2 0.017
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.017
signal transduction by phosphorylation GO:0023014 18 0.017
establishment of localization GO:0051234 244 0.017
specification of organ identity GO:0010092 2 0.016
stem cell development GO:0048864 82 0.016
regulation of gene expression GO:0010468 265 0.016
Mouse
regulation of programmed cell death GO:0043067 101 0.016
cardiocyte differentiation GO:0035051 44 0.016
digestive tract morphogenesis GO:0048546 231 0.016
regulation of transcription dna templated GO:0006355 213 0.016
Mouse
single organism transport GO:0044765 206 0.016
positive regulation of phosphorus metabolic process GO:0010562 21 0.016
Zebrafish
peptide transport GO:0015833 1 0.016
positive regulation of muscle tissue development GO:1901863 1 0.016
monoamine transport GO:0015844 1 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
ear development GO:0043583 127 0.016
endocrine process GO:0050886 2 0.016
response to abiotic stimulus GO:0009628 122 0.016
positive regulation of cytoskeleton organization GO:0051495 3 0.016
zymogen activation GO:0031638 3 0.015
regulation of cell activation GO:0050865 1 0.015
activation of mapk activity GO:0000187 3 0.015
rhodopsin mediated signaling pathway GO:0016056 1 0.015
regulation of tube size GO:0035150 2 0.015
tyrosine phosphorylation of stat protein GO:0007260 1 0.015
pericardium morphogenesis GO:0003344 1 0.015
regulation of localization GO:0032879 104 0.015
actin filament based process GO:0030029 64 0.015
carbohydrate derivative metabolic process GO:1901135 61 0.015
Zebrafish
connective tissue development GO:0061448 99 0.015
negative regulation of nuclear division GO:0051784 3 0.015
response to mechanical stimulus GO:0009612 24 0.015
microglia differentiation GO:0014004 1 0.015
positive regulation of phosphate metabolic process GO:0045937 21 0.015
Zebrafish
retina development in camera type eye GO:0060041 146 0.015
heart process GO:0003015 71 0.015
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.015
regulation of cellular component organization GO:0051128 86 0.015
anion transport GO:0006820 38 0.015
metal ion transport GO:0030001 58 0.015
regulation of neuron migration GO:2001222 2 0.015
negative regulation of mitosis GO:0045839 3 0.015
regionalization GO:0003002 274 0.015
calcium ion transport into cytosol GO:0060402 3 0.015
apoptotic process GO:0006915 116 0.014
organic hydroxy compound biosynthetic process GO:1901617 6 0.014
Mouse
transport GO:0006810 220 0.014
cell projection assembly GO:0030031 64 0.014
regulation of heart contraction GO:0008016 32 0.014
positive regulation of map kinase activity GO:0043406 3 0.014
cell death GO:0008219 121 0.014
positive regulation of cell death GO:0010942 29 0.014
mechanosensory behavior GO:0007638 2 0.014
epithelial tube morphogenesis GO:0060562 148 0.014
organelle localization GO:0051640 49 0.014
lipid storage GO:0019915 1 0.014
regulation of bmp signaling pathway GO:0030510 39 0.014
regulation of neural retina development GO:0061074 2 0.014
regulation of homeostatic process GO:0032844 9 0.014
developmental maturation GO:0021700 34 0.014
sensory organ morphogenesis GO:0090596 200 0.014
pericardium development GO:0060039 1 0.014
positive regulation of signal transduction GO:0009967 56 0.014
Mouse
optic placode formation GO:0001743 4 0.014
regulation of dendrite morphogenesis GO:0048814 3 0.014
response to wounding GO:0009611 116 0.014
aorta morphogenesis GO:0035909 3 0.014
formation of primary germ layer GO:0001704 62 0.014
striated muscle cell differentiation GO:0051146 129 0.013
cellular protein metabolic process GO:0044267 129 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
blood vessel morphogenesis GO:0048514 216 0.013
epithelial cell cell adhesion GO:0090136 1 0.013
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.013
bmp signaling pathway GO:0030509 52 0.013
epidermal cell differentiation GO:0009913 36 0.013
response to lipid GO:0033993 60 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
response to alkaloid GO:0043279 2 0.013
cell matrix adhesion GO:0007160 4 0.013
regulation of neuron projection development GO:0010975 40 0.013
rna biosynthetic process GO:0032774 181 0.013
Mouse
response to hydrogen peroxide GO:0042542 3 0.013
fat soluble vitamin metabolic process GO:0006775 4 0.012
release of sequestered calcium ion into cytosol GO:0051209 3 0.012
regulation of nervous system development GO:0051960 90 0.012
aorta development GO:0035904 4 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
positive regulation of transcription dna templated GO:0045893 57 0.012
Mouse
hair cell differentiation GO:0035315 32 0.012
lamellipodium organization GO:0097581 1 0.012
protein phosphorylation GO:0006468 47 0.012
positive regulation of apoptotic process GO:0043065 29 0.012
regulation of multicellular organismal metabolic process GO:0044246 2 0.012
regulation of growth GO:0040008 42 0.012
Zebrafish
regulation of wnt signaling pathway GO:0030111 53 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
regulation of oligodendrocyte differentiation GO:0048713 1 0.012
cytosolic calcium ion transport GO:0060401 3 0.012
positive regulation of cell cycle GO:0045787 3 0.012
alcohol metabolic process GO:0006066 11 0.012
regulation of microtubule cytoskeleton organization GO:0070507 3 0.012
wnt signaling pathway GO:0016055 80 0.012
response to hormone GO:0009725 48 0.012
synapse assembly GO:0007416 9 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
negative regulation of blood circulation GO:1903523 2 0.012
cell proliferation GO:0008283 80 0.012
angiogenesis GO:0001525 158 0.012
transcription dna templated GO:0006351 181 0.012
Mouse
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.012
protein localization to nucleus GO:0034504 3 0.012
response to steroid hormone GO:0048545 35 0.011
cell cell junction organization GO:0045216 10 0.011
positive regulation of immune effector process GO:0002699 3 0.011
cell growth GO:0016049 57 0.011
establishment of localization in cell GO:0051649 77 0.011
dendrite morphogenesis GO:0048813 5 0.011
negative regulation of nucleotide biosynthetic process GO:0030809 7 0.011
regulation of cellular component biogenesis GO:0044087 12 0.011
cardiac atrium development GO:0003230 4 0.011
negative regulation of cellular biosynthetic process GO:0031327 55 0.011
t cell differentiation in thymus GO:0033077 6 0.011
response to drug GO:0042493 3 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
muscle organ development GO:0007517 101 0.011
response to inorganic substance GO:0010035 38 0.011
fatty acid biosynthetic process GO:0006633 4 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.011
ovarian follicle development GO:0001541 2 0.011
response to nitrogen compound GO:1901698 19 0.011
regulation of cellular component movement GO:0051270 55 0.011

mc1r disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.079
nervous system disease DOID:863 0 0.013
bone development disease DOID:0080006 0 0.011
bone disease DOID:0080001 0 0.011
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011