Danio rerio

0 known processes

gadd45g

growth arrest and DNA-damage-inducible, gamma

(Aliases: MGC77806,zgc:77806)

gadd45g biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of p38mapk cascade GO:1900744 1 0.215
Human
regulation of response to stimulus GO:0048583 269 0.134
Human Mouse
regulation of signaling GO:0023051 235 0.113
Human Mouse
p38mapk cascade GO:0038066 1 0.108
Human
single organism metabolic process GO:0044710 217 0.098
Human Mouse
negative regulation of kinase activity GO:0033673 4 0.094
Mouse
positive regulation of biological process GO:0048518 253 0.094
Human Mouse
negative regulation of cellular process GO:0048523 283 0.087
Mouse
regulation of apoptotic process GO:0042981 98 0.087
Human
purine ribonucleotide biosynthetic process GO:0009152 20 0.082
response to organic substance GO:0010033 153 0.079
Zebrafish
response to stress GO:0006950 263 0.078
Human
regulation of primary metabolic process GO:0080090 311 0.074
Human Mouse
embryonic organ development GO:0048568 381 0.071
multicellular organismal metabolic process GO:0044236 2 0.064
carboxylic acid metabolic process GO:0019752 22 0.061
aging GO:0007568 2 0.061
cellular response to radiation GO:0071478 4 0.059
organic acid metabolic process GO:0006082 31 0.055
lipid storage GO:0019915 1 0.055
negative regulation of phosphate metabolic process GO:0045936 13 0.055
Mouse
regulation of nucleoside metabolic process GO:0009118 2 0.051
negative regulation of protein phosphorylation GO:0001933 4 0.049
Mouse
cellular biosynthetic process GO:0044249 286 0.049
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.048
signal transduction GO:0007165 455 0.048
Human Mouse
activation of mapkkk activity GO:0000185 1 0.047
Human
cell death GO:0008219 121 0.047
Human
regulation of epithelial cell proliferation GO:0050678 3 0.047
alpha amino acid metabolic process GO:1901605 3 0.046
system process GO:0003008 185 0.046
response to amino acid GO:0043200 2 0.046
oxoacid metabolic process GO:0043436 31 0.046
positive regulation of transport GO:0051050 2 0.046
maintenance of location GO:0051235 4 0.045
small molecule metabolic process GO:0044281 77 0.045
regulation of cellular metabolic process GO:0031323 320 0.045
Human Mouse
response to glucocorticoid GO:0051384 1 0.045
tyrosine phosphorylation of stat protein GO:0007260 1 0.044
response to nutrient GO:0007584 3 0.044
purine containing compound metabolic process GO:0072521 29 0.044
positive regulation of cellular catabolic process GO:0031331 3 0.043
regulation of nitrogen compound metabolic process GO:0051171 251 0.043
positive regulation of catabolic process GO:0009896 4 0.043
cellular ketone metabolic process GO:0042180 11 0.042
programmed cell death GO:0012501 119 0.040
Human
response to corticosteroid GO:0031960 1 0.039
response to metal ion GO:0010038 34 0.039
Zebrafish
cellular protein catabolic process GO:0044257 4 0.038
organonitrogen compound metabolic process GO:1901564 74 0.038
phosphorus metabolic process GO:0006793 109 0.038
Human Mouse
amine metabolic process GO:0009308 2 0.038
cellular amino acid metabolic process GO:0006520 7 0.037
response to vitamin GO:0033273 3 0.037
multicellular organism growth GO:0035264 4 0.036
regulation of signal transduction GO:0009966 225 0.035
Human Mouse
mesoderm development GO:0007498 88 0.035
Zebrafish
larval development GO:0002164 2 0.034
intracellular signal transduction GO:0035556 85 0.034
Human Mouse
nuclear transport GO:0051169 4 0.034
death GO:0016265 121 0.033
Human
organic cyclic compound biosynthetic process GO:1901362 223 0.033
g1 s transition of mitotic cell cycle GO:0000082 1 0.033
positive regulation of cellular process GO:0048522 201 0.032
Human Mouse
response to transition metal nanoparticle GO:1990267 28 0.032
Zebrafish
cellular aromatic compound metabolic process GO:0006725 295 0.032
cellular response to stress GO:0033554 62 0.031
Human
organophosphate metabolic process GO:0019637 37 0.031
notochord development GO:0030903 54 0.030
negative regulation of protein kinase activity GO:0006469 4 0.030
Mouse
rna metabolic process GO:0016070 219 0.030
regulation of multicellular organism growth GO:0040014 4 0.030
phosphorylation GO:0016310 69 0.029
Human Mouse
regulation of programmed cell death GO:0043067 101 0.029
Human
protein metabolic process GO:0019538 183 0.029
Human Mouse
ion transport GO:0006811 114 0.029
regulation of developmental process GO:0050793 247 0.029
regulation of cell death GO:0010941 103 0.028
Human
protein modification process GO:0036211 100 0.028
Human Mouse
synaptic growth at neuromuscular junction GO:0051124 2 0.028
nitrogen compound metabolic process GO:0006807 319 0.027
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.027
regulation of protein transport GO:0051223 3 0.027
positive regulation of cell cycle GO:0045787 3 0.027
cellular carbohydrate metabolic process GO:0044262 4 0.027
response to ketone GO:1901654 1 0.027
phosphate containing compound metabolic process GO:0006796 108 0.027
Human Mouse
regulation of blood vessel size GO:0050880 2 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.026
regulation of nucleotide catabolic process GO:0030811 2 0.025
heterocycle metabolic process GO:0046483 290 0.025
nucleocytoplasmic transport GO:0006913 4 0.025
positive regulation of cellular metabolic process GO:0031325 94 0.025
Human Mouse
tissue remodeling GO:0048771 4 0.025
embryo development ending in birth or egg hatching GO:0009792 271 0.025
Zebrafish
response to wounding GO:0009611 116 0.024
hemopoiesis GO:0030097 183 0.024
macromolecule modification GO:0043412 111 0.024
Human Mouse
proteasomal protein catabolic process GO:0010498 2 0.024
positive regulation of stress activated mapk cascade GO:0032874 3 0.024
Human
positive regulation of cellular component biogenesis GO:0044089 3 0.024
collagen metabolic process GO:0032963 2 0.024
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.023
regulation of tube size GO:0035150 2 0.023
response to carbohydrate GO:0009743 3 0.023
establishment of protein localization to organelle GO:0072594 4 0.023
morphogenesis of an epithelium GO:0002009 333 0.022
regulation of multicellular organismal process GO:0051239 277 0.022
meiotic nuclear division GO:0007126 4 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
transport GO:0006810 220 0.022
mesenchyme development GO:0060485 127 0.022
Zebrafish
female gonad development GO:0008585 4 0.022
positive regulation of metabolic process GO:0009893 108 0.022
Human Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.022
establishment of localization GO:0051234 244 0.022
organic cyclic compound metabolic process GO:1901360 301 0.022
positive regulation of response to stimulus GO:0048584 80 0.022
Human Mouse
regulation of binding GO:0051098 3 0.022
single organism transport GO:0044765 206 0.022
regulation of phosphate metabolic process GO:0019220 43 0.022
Human Mouse
regulation of establishment of protein localization GO:0070201 4 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
b cell differentiation GO:0030183 1 0.021
cellular macromolecule metabolic process GO:0044260 391 0.021
Human Mouse
regulation of molecular function GO:0065009 70 0.021
Human Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.021
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.021
Human
regulation of cell communication GO:0010646 232 0.021
Human Mouse
nucleic acid metabolic process GO:0090304 244 0.021
regulation of metal ion transport GO:0010959 4 0.021
protein targeting to nucleus GO:0044744 3 0.021
cellular amine metabolic process GO:0044106 2 0.021
positive regulation of signal transduction GO:0009967 56 0.021
Human Mouse
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.021
cellular nitrogen compound metabolic process GO:0034641 290 0.021
long chain fatty acid metabolic process GO:0001676 1 0.021
negative regulation of metabolic process GO:0009892 86 0.020
Mouse
cellular protein metabolic process GO:0044267 129 0.020
Human Mouse
negative regulation of epithelial cell proliferation GO:0050680 1 0.020
transcription from rna polymerase ii promoter GO:0006366 80 0.020
circulatory system process GO:0003013 87 0.020
response to organic cyclic compound GO:0014070 51 0.020
regulation of cellular biosynthetic process GO:0031326 245 0.020
cell cycle g1 s phase transition GO:0044843 1 0.020
somite development GO:0061053 96 0.020
Zebrafish
regulation of intracellular signal transduction GO:1902531 57 0.020
Human Mouse
cell cycle arrest GO:0007050 1 0.020
negative regulation of catalytic activity GO:0043086 21 0.020
Mouse
locomotor rhythm GO:0045475 3 0.019
regulation of biological quality GO:0065008 263 0.019
negative regulation of macromolecule metabolic process GO:0010605 76 0.019
Mouse
protein import into nucleus GO:0006606 3 0.019
response to external stimulus GO:0009605 264 0.019
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 1 0.019
compound eye development GO:0048749 2 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
fatty acid transport GO:0015908 1 0.019
long chain fatty acid transport GO:0015909 1 0.019
cellular component movement GO:0006928 335 0.019
regulation of rna biosynthetic process GO:2001141 213 0.018
positive regulation of apoptotic signaling pathway GO:2001235 1 0.018
nuclear import GO:0051170 3 0.018
regulation of response to stress GO:0080134 36 0.018
Human
mitochondrion organization GO:0007005 4 0.018
negative regulation of protein complex assembly GO:0031333 1 0.018
regulation of macromolecule biosynthetic process GO:0010556 225 0.018
cellular response to external stimulus GO:0071496 2 0.018
regulation of locomotion GO:0040012 55 0.018
skin development GO:0043588 54 0.018
regulation of hormone secretion GO:0046883 2 0.018
digestive system development GO:0055123 289 0.018
vasculature development GO:0001944 278 0.018
enzyme linked receptor protein signaling pathway GO:0007167 106 0.018
mitotic dna damage checkpoint GO:0044773 4 0.018
regulation of response to interferon gamma GO:0060330 1 0.017
mapk cascade GO:0000165 18 0.017
Human Mouse
purine nucleoside monophosphate catabolic process GO:0009128 4 0.017
regulation of jak stat cascade GO:0046425 3 0.017
response to inorganic substance GO:0010035 38 0.017
Zebrafish
single organism nuclear import GO:1902593 3 0.017
regulation of catalytic activity GO:0050790 55 0.017
Human Mouse
apoptotic process GO:0006915 116 0.017
Human
heterocycle biosynthetic process GO:0018130 215 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.017
single organism organelle organization GO:1902589 199 0.017
cellular modified amino acid metabolic process GO:0006575 3 0.017
tyrosine phosphorylation of stat3 protein GO:0042503 1 0.017
blood circulation GO:0008015 87 0.017
response to chemical GO:0042221 320 0.017
Zebrafish
cellular response to light stimulus GO:0071482 4 0.016
regulation of inflammatory response GO:0050727 2 0.016
regeneration GO:0031099 91 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.016
protein import GO:0017038 3 0.016
determination of bilateral symmetry GO:0009855 204 0.016
regulation of skeletal muscle fiber development GO:0048742 2 0.016
aromatic compound biosynthetic process GO:0019438 217 0.016
regulation of myotube differentiation GO:0010830 2 0.016
nucleoside phosphate metabolic process GO:0006753 28 0.016
ribonucleotide metabolic process GO:0009259 27 0.016
response to abiotic stimulus GO:0009628 122 0.016
regulation of nucleic acid templated transcription GO:1903506 213 0.016
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.016
cell migration GO:0016477 237 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
regulation of metabolic process GO:0019222 359 0.015
Human Mouse
cell proliferation GO:0008283 80 0.015
ovarian follicle development GO:0001541 2 0.015
negative regulation of biological process GO:0048519 304 0.015
Mouse
brain development GO:0007420 293 0.015
positive regulation of cell death GO:0010942 29 0.015
Human
regulation of cytoplasmic transport GO:1903649 4 0.015
ribose phosphate metabolic process GO:0019693 27 0.015
locomotion GO:0040011 313 0.015
purine ribonucleoside biosynthetic process GO:0046129 2 0.015
mitotic dna integrity checkpoint GO:0044774 4 0.015
cellular response to starvation GO:0009267 1 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
cellular protein modification process GO:0006464 100 0.015
Human Mouse
myeloid cell homeostasis GO:0002262 56 0.015
regulation of carbohydrate metabolic process GO:0006109 4 0.015
single organism localization GO:1902578 225 0.015
response to antibiotic GO:0046677 1 0.015
single organism biosynthetic process GO:0044711 71 0.014
negative regulation of nuclear division GO:0051784 3 0.014
nucleotide biosynthetic process GO:0009165 21 0.014
chordate embryonic development GO:0043009 271 0.014
Zebrafish
immune system development GO:0002520 191 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
negative regulation of defense response GO:0031348 2 0.014
diterpenoid metabolic process GO:0016101 15 0.014
sleep GO:0030431 1 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
response to endogenous stimulus GO:0009719 83 0.014
regulation of cellular protein catabolic process GO:1903362 1 0.014
b cell activation GO:0042113 2 0.014
rna biosynthetic process GO:0032774 181 0.014
wound healing GO:0042060 90 0.014
positive regulation of cell communication GO:0010647 56 0.014
Human Mouse
response to hexose GO:0009746 3 0.014
regulation of calcium ion transport GO:0051924 2 0.014
response to monosaccharide GO:0034284 3 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
regulation of skeletal muscle tissue development GO:0048641 4 0.013
positive regulation of translation GO:0045727 1 0.013
response to hormone GO:0009725 48 0.013
purine nucleotide metabolic process GO:0006163 27 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
regulation of reproductive process GO:2000241 4 0.013
protein localization to nucleus GO:0034504 3 0.013
regulation of cellular protein metabolic process GO:0032268 52 0.013
Human Mouse
regulation of localization GO:0032879 104 0.013
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.013
gtp metabolic process GO:0046039 4 0.013
adult behavior GO:0030534 2 0.013
regulation of kinase activity GO:0043549 15 0.013
Human Mouse
epidermal cell differentiation GO:0009913 36 0.013
regulation of cell cycle GO:0051726 52 0.013
Mouse
photoreceptor cell fate commitment GO:0046552 1 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
regulation of systemic arterial blood pressure GO:0003073 1 0.013
multicellular organismal response to stress GO:0033555 2 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
positive regulation of multicellular organismal process GO:0051240 52 0.013
cellular macromolecule biosynthetic process GO:0034645 224 0.013
cellular nitrogen compound biosynthetic process GO:0044271 218 0.012
neurological system process GO:0050877 62 0.012
response to uv GO:0009411 3 0.012
cellular response to decreased oxygen levels GO:0036294 1 0.012
antimicrobial humoral response GO:0019730 2 0.012
kidney development GO:0001822 92 0.012
ribonucleoside biosynthetic process GO:0042455 2 0.012
circadian sleep wake cycle GO:0042745 2 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
regulation of protein catabolic process GO:0042176 1 0.012
blood vessel morphogenesis GO:0048514 216 0.012
positive regulation of camp biosynthetic process GO:0030819 2 0.012
response to steroid hormone GO:0048545 35 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
regulation of gtpase activity GO:0043087 2 0.012
female sex differentiation GO:0046660 4 0.012
regulation of interferon gamma mediated signaling pathway GO:0060334 1 0.012
biosynthetic process GO:0009058 294 0.012
cellular response to organic substance GO:0071310 105 0.012
signal transduction in absence of ligand GO:0038034 1 0.012
osteoclast differentiation GO:0030316 1 0.012
positive regulation of developmental process GO:0051094 50 0.012
response to oxygen levels GO:0070482 25 0.012
neuron projection regeneration GO:0031102 16 0.012
regulation of cellular response to stress GO:0080135 20 0.012
Human
regulation of lipid transport GO:0032368 4 0.012
negative regulation of response to cytokine stimulus GO:0060761 2 0.012
purine nucleotide biosynthetic process GO:0006164 20 0.012
nucleic acid templated transcription GO:0097659 181 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
developmental growth GO:0048589 166 0.012
interferon gamma mediated signaling pathway GO:0060333 1 0.012
protein localization to plasma membrane GO:0072659 1 0.012
central nervous system development GO:0007417 387 0.012
cell projection organization GO:0030030 284 0.012
regulation of cell motility GO:2000145 46 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
multicellular organismal macromolecule metabolic process GO:0044259 2 0.012
modification dependent protein catabolic process GO:0019941 3 0.011
regulation of phosphorus metabolic process GO:0051174 43 0.011
Human Mouse
hormone secretion GO:0046879 2 0.011
regulation of synapse organization GO:0050807 3 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
Human Mouse
positive regulation of myeloid cell differentiation GO:0045639 2 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
regulation of synapse assembly GO:0051963 3 0.011
positive regulation of biosynthetic process GO:0009891 68 0.011
paraxial mesoderm development GO:0048339 8 0.011
Zebrafish
negative regulation of innate immune response GO:0045824 2 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
organism emergence from protective structure GO:0071684 4 0.011
response to methylmercury GO:0051597 11 0.011
Zebrafish
establishment of rna localization GO:0051236 3 0.011
terpenoid metabolic process GO:0006721 15 0.011
cell aging GO:0007569 2 0.011
circadian sleep wake cycle sleep GO:0050802 1 0.011
regulation of cellular component organization GO:0051128 86 0.011
gene expression GO:0010467 252 0.011
guanosine containing compound metabolic process GO:1901068 4 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
positive regulation of secretion GO:0051047 1 0.011
autophagy GO:0006914 4 0.011
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 10 0.011
positive regulation of jak stat cascade GO:0046427 2 0.011
nucleoside biosynthetic process GO:0009163 2 0.011
nucleic acid transport GO:0050657 2 0.011
estrogen metabolic process GO:0008210 2 0.011
nuclear export GO:0051168 1 0.011
lipid homeostasis GO:0055088 3 0.011
macromolecule biosynthetic process GO:0009059 227 0.011
nucleobase containing small molecule metabolic process GO:0055086 32 0.011
macromolecule localization GO:0033036 54 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
negative regulation of muscle cell differentiation GO:0051148 1 0.011
cellular response to hypoxia GO:0071456 1 0.011
cellular amino acid biosynthetic process GO:0008652 2 0.011
acylglycerol homeostasis GO:0055090 2 0.011
cell death in response to oxidative stress GO:0036473 2 0.010
regulation of circadian sleep wake cycle GO:0042749 1 0.010
ovulation cycle process GO:0022602 2 0.010
regulation of circadian rhythm GO:0042752 4 0.010
response to lipid GO:0033993 60 0.010
hormone biosynthetic process GO:0042446 3 0.010
cellular response to chemical stimulus GO:0070887 157 0.010
positive regulation of epithelial cell differentiation GO:0030858 2 0.010
liver development GO:0001889 96 0.010
response to drug GO:0042493 3 0.010
epidermis development GO:0008544 48 0.010
regulation of cytokine production GO:0001817 3 0.010
cellular response to nutrient levels GO:0031669 2 0.010
cellular sodium ion homeostasis GO:0006883 1 0.010
response to food GO:0032094 1 0.010
nucleobase containing compound metabolic process GO:0006139 274 0.010
regulation of multicellular organismal metabolic process GO:0044246 2 0.010
regulation of purine nucleotide catabolic process GO:0033121 2 0.010
transmembrane transport GO:0055085 120 0.010

gadd45g disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013