Danio rerio

89 known processes

dhrs9

dehydrogenase/reductase (SDR family) member 9

(Aliases: rdh1l,wu:fb64b07,zgc:73286,RDHA)

dhrs9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
fat soluble vitamin metabolic process GO:0006775 4 0.408
Zebrafish
response to external stimulus GO:0009605 264 0.318
central nervous system development GO:0007417 387 0.239
hepaticobiliary system development GO:0061008 98 0.205
regulation of cellular metabolic process GO:0031323 320 0.161
response to organic substance GO:0010033 153 0.160
biosynthetic process GO:0009058 294 0.150
Zebrafish
liver development GO:0001889 96 0.143
regulation of primary metabolic process GO:0080090 311 0.139
regulation of response to external stimulus GO:0032101 31 0.137
response to chemical GO:0042221 320 0.131
regulation of macromolecule metabolic process GO:0060255 317 0.118
diterpenoid metabolic process GO:0016101 15 0.106
cellular nitrogen compound metabolic process GO:0034641 290 0.099
brain development GO:0007420 293 0.098
cell surface receptor signaling pathway GO:0007166 325 0.098
neuron differentiation GO:0030182 353 0.097
Zebrafish
cell death GO:0008219 121 0.097
neuron development GO:0048666 262 0.096
aging GO:0007568 2 0.094
nitrogen compound metabolic process GO:0006807 319 0.092
generation of neurons GO:0048699 385 0.089
Zebrafish
single organism biosynthetic process GO:0044711 71 0.087
Zebrafish
lipid storage GO:0019915 1 0.086
single organism metabolic process GO:0044710 217 0.083
gene expression GO:0010467 252 0.080
response to nutrient GO:0007584 3 0.079
locomotion GO:0040011 313 0.078
regulation of rna biosynthetic process GO:2001141 213 0.078
morphogenesis of an epithelium GO:0002009 333 0.076
response to lipid GO:0033993 60 0.072
regulation of wound healing GO:0061041 2 0.069
retinoid metabolic process GO:0001523 15 0.067
regulation of metabolic process GO:0019222 359 0.067
tube morphogenesis GO:0035239 349 0.066
cellular biosynthetic process GO:0044249 286 0.066
Zebrafish
regulation of inflammatory response GO:0050727 2 0.064
regulation of multicellular organismal process GO:0051239 277 0.063
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.063
cellular nitrogen compound biosynthetic process GO:0044271 218 0.062
apoptotic process GO:0006915 116 0.062
epithelial tube morphogenesis GO:0060562 148 0.061
regulation of cytokine production GO:0001817 3 0.061
aromatic compound biosynthetic process GO:0019438 217 0.060
cellular component morphogenesis GO:0032989 336 0.060
response to steroid hormone GO:0048545 35 0.059
small molecule metabolic process GO:0044281 77 0.057
cellular response to lipopolysaccharide GO:0071222 3 0.056
oxidation reduction process GO:0055114 41 0.056
response to vitamin GO:0033273 3 0.055
regulation of cell activation GO:0050865 1 0.054
negative regulation of cellular process GO:0048523 283 0.054
multicellular organism growth GO:0035264 4 0.054
organic cyclic compound metabolic process GO:1901360 301 0.054
cellular amino acid metabolic process GO:0006520 7 0.054
negative regulation of protein phosphorylation GO:0001933 4 0.053
response to stress GO:0006950 263 0.053
Zebrafish
larval development GO:0002164 2 0.052
transcription dna templated GO:0006351 181 0.051
nucleobase containing compound biosynthetic process GO:0034654 205 0.051
heterocycle metabolic process GO:0046483 290 0.051
oxoacid metabolic process GO:0043436 31 0.051
signal transduction GO:0007165 455 0.050
digestive tract development GO:0048565 265 0.050
negative regulation of response to stimulus GO:0048585 104 0.050
superoxide metabolic process GO:0006801 2 0.049
terpenoid metabolic process GO:0006721 15 0.049
negative regulation of metabolic process GO:0009892 86 0.048
embryonic heart tube development GO:0035050 133 0.048
ameboidal type cell migration GO:0001667 143 0.047
regulation of gene expression GO:0010468 265 0.046
cellular protein metabolic process GO:0044267 129 0.044
regulation of protein polymerization GO:0032271 2 0.044
cellular response to chemical stimulus GO:0070887 157 0.044
positive regulation of macromolecule metabolic process GO:0010604 93 0.044
regulation of transcription dna templated GO:0006355 213 0.043
neurotransmitter secretion GO:0007269 2 0.043
organonitrogen compound metabolic process GO:1901564 74 0.043
eye development GO:0001654 277 0.043
Zebrafish
digestive system development GO:0055123 289 0.043
rna biosynthetic process GO:0032774 181 0.042
regulation of protein complex assembly GO:0043254 3 0.042
regulation of response to stimulus GO:0048583 269 0.042
regulation of biosynthetic process GO:0009889 250 0.042
negative regulation of biological process GO:0048519 304 0.042
response to external biotic stimulus GO:0043207 97 0.041
regulation of multicellular organism growth GO:0040014 4 0.041
positive regulation of cellular component biogenesis GO:0044089 3 0.041
embryonic organ development GO:0048568 381 0.041
guanosine containing compound catabolic process GO:1901069 2 0.041
regulation of response to stress GO:0080134 36 0.041
positive regulation of catabolic process GO:0009896 4 0.041
cell migration GO:0016477 237 0.041
regulation of biological quality GO:0065008 263 0.041
organic cyclic compound biosynthetic process GO:1901362 223 0.040
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.040
camera type eye development GO:0043010 222 0.040
Zebrafish
positive regulation of transport GO:0051050 2 0.039
hormone biosynthetic process GO:0042446 3 0.038
negative regulation of cell death GO:0060548 60 0.038
protein metabolic process GO:0019538 183 0.038
sensory organ morphogenesis GO:0090596 200 0.038
Zebrafish
multicellular organismal metabolic process GO:0044236 2 0.037
heterocycle biosynthetic process GO:0018130 215 0.037
maintenance of location GO:0051235 4 0.037
carboxylic acid metabolic process GO:0019752 22 0.037
guanosine containing compound metabolic process GO:1901068 4 0.036
neuron projection development GO:0031175 180 0.036
homeostatic process GO:0042592 142 0.036
positive regulation of biological process GO:0048518 253 0.036
retina development in camera type eye GO:0060041 146 0.035
Zebrafish
death GO:0016265 121 0.035
cellular extravasation GO:0045123 1 0.035
regulation of hormone secretion GO:0046883 2 0.035
cellular amide metabolic process GO:0043603 4 0.035
organic acid metabolic process GO:0006082 31 0.035
cytoskeleton organization GO:0007010 96 0.035
positive regulation of cellular process GO:0048522 201 0.034
negative regulation of protein kinase activity GO:0006469 4 0.034
cellular macromolecule metabolic process GO:0044260 391 0.034
regulation of rna metabolic process GO:0051252 224 0.034
organic substance biosynthetic process GO:1901576 289 0.034
Zebrafish
positive regulation of cellular catabolic process GO:0031331 3 0.034
cellular response to external stimulus GO:0071496 2 0.033
regulation of cellular biosynthetic process GO:0031326 245 0.033
cell projection morphogenesis GO:0048858 244 0.033
response to drug GO:0042493 3 0.032
wound healing GO:0042060 90 0.032
response to oxygen containing compound GO:1901700 55 0.032
sensory organ development GO:0007423 393 0.031
Zebrafish
neurotransmitter transport GO:0006836 2 0.031
cellular response to organic cyclic compound GO:0071407 38 0.030
multicellular organismal homeostasis GO:0048871 29 0.030
regulation of tube size GO:0035150 2 0.030
cellular response to biotic stimulus GO:0071216 3 0.030
nucleobase containing compound metabolic process GO:0006139 274 0.030
determination of heart left right asymmetry GO:0061371 117 0.029
regulation of metal ion transport GO:0010959 4 0.029
circulatory system process GO:0003013 87 0.029
negative regulation of cell communication GO:0010648 96 0.029
negative regulation of signal transduction GO:0009968 94 0.029
positive regulation of protein complex assembly GO:0031334 2 0.028
tissue remodeling GO:0048771 4 0.028
cellular modified amino acid metabolic process GO:0006575 3 0.028
positive regulation of cytoskeleton organization GO:0051495 3 0.028
regulation of macromolecule biosynthetic process GO:0010556 225 0.028
retinoic acid metabolic process GO:0042573 9 0.028
cell motility GO:0048870 244 0.028
gland development GO:0048732 143 0.028
immune system process GO:0002376 241 0.027
astrocyte differentiation GO:0048708 1 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.027
regulation of apoptotic process GO:0042981 98 0.026
response to organic cyclic compound GO:0014070 51 0.026
programmed cell death GO:0012501 119 0.026
positive regulation of metabolic process GO:0009893 108 0.026
inner ear development GO:0048839 126 0.026
negative regulation of signaling GO:0023057 96 0.026
cellular response to molecule of bacterial origin GO:0071219 3 0.026
protein modification process GO:0036211 100 0.026
positive regulation of cellular extravasation GO:0002693 1 0.025
collagen metabolic process GO:0032963 2 0.025
developmental growth GO:0048589 166 0.025
lipid biosynthetic process GO:0008610 22 0.025
Zebrafish
response to bacterium GO:0009617 58 0.025
regulation of programmed cell death GO:0043067 101 0.025
pectoral fin development GO:0033339 50 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.025
phosphorus metabolic process GO:0006793 109 0.025
cellular lipid metabolic process GO:0044255 36 0.025
regulation of nitrogen compound metabolic process GO:0051171 251 0.025
heart morphogenesis GO:0003007 156 0.024
protein polymerization GO:0051258 4 0.024
cellular aromatic compound metabolic process GO:0006725 295 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
negative regulation of cellular metabolic process GO:0031324 77 0.024
negative regulation of programmed cell death GO:0043069 58 0.024
camera type eye morphogenesis GO:0048593 108 0.023
regulation of signal transduction GO:0009966 225 0.023
response to wounding GO:0009611 116 0.023
regulation of nucleic acid templated transcription GO:1903506 213 0.023
regulation of catalytic activity GO:0050790 55 0.023
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.023
organic acid catabolic process GO:0016054 3 0.022
regulation of jun kinase activity GO:0043506 3 0.022
regulation of cellular ketone metabolic process GO:0010565 7 0.022
hindbrain development GO:0030902 91 0.022
positive regulation of cytokine production GO:0001819 2 0.022
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.022
regulation of blood vessel size GO:0050880 2 0.022
cellular response to organic substance GO:0071310 105 0.022
regulation of protein metabolic process GO:0051246 56 0.022
adherens junction organization GO:0034332 4 0.022
phosphate containing compound metabolic process GO:0006796 108 0.021
response to hormone GO:0009725 48 0.021
regulation of cell death GO:0010941 103 0.021
positive regulation of cellular metabolic process GO:0031325 94 0.021
amine metabolic process GO:0009308 2 0.021
response to carbohydrate GO:0009743 3 0.021
head development GO:0060322 303 0.021
regulation of hemostasis GO:1900046 1 0.020
nucleic acid templated transcription GO:0097659 181 0.020
localization of cell GO:0051674 244 0.020
vitamin metabolic process GO:0006766 11 0.020
Zebrafish
diterpenoid biosynthetic process GO:0016102 7 0.020
Zebrafish
regulation of endopeptidase activity GO:0052548 23 0.020
system process GO:0003008 185 0.020
cellular response to endogenous stimulus GO:0071495 68 0.020
cell part morphogenesis GO:0032990 246 0.020
cellular component movement GO:0006928 335 0.020
vasculature development GO:0001944 278 0.020
regulation of molecular function GO:0065009 70 0.020
gliogenesis GO:0042063 45 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.020
multicellular organismal macromolecule metabolic process GO:0044259 2 0.019
response to abiotic stimulus GO:0009628 122 0.019
response to other organism GO:0051707 97 0.019
neuron projection morphogenesis GO:0048812 161 0.019
heart looping GO:0001947 94 0.019
leukocyte differentiation GO:0002521 25 0.019
regulation of protein catabolic process GO:0042176 1 0.019
response to monosaccharide GO:0034284 3 0.019
alpha amino acid metabolic process GO:1901605 3 0.019
negative regulation of gene expression GO:0010629 65 0.019
transcription from rna polymerase ii promoter GO:0006366 80 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.019
epithelial cell differentiation GO:0030855 116 0.019
Zebrafish
macromolecule biosynthetic process GO:0009059 227 0.019
small molecule biosynthetic process GO:0044283 16 0.019
Zebrafish
negative regulation of mapk cascade GO:0043409 4 0.019
regulation of muscle contraction GO:0006937 3 0.019
embryonic heart tube morphogenesis GO:0003143 108 0.018
regulation of microtubule cytoskeleton organization GO:0070507 3 0.018
regulation of blood coagulation GO:0030193 1 0.018
embryonic limb morphogenesis GO:0030326 2 0.018
positive regulation of secretion by cell GO:1903532 1 0.018
organic acid biosynthetic process GO:0016053 12 0.018
peptide metabolic process GO:0006518 1 0.018
cellular response to stress GO:0033554 62 0.017
intracellular receptor signaling pathway GO:0030522 30 0.017
regulation of signaling GO:0023051 235 0.017
regulation of reactive oxygen species metabolic process GO:2000377 2 0.017
gtp catabolic process GO:0006184 2 0.017
regulation of cellular extravasation GO:0002691 1 0.017
nephron tubule morphogenesis GO:0072078 1 0.017
microtubule polymerization or depolymerization GO:0031109 3 0.017
response to endogenous stimulus GO:0009719 83 0.017
cell morphogenesis GO:0000902 289 0.017
protein processing GO:0016485 12 0.017
positive regulation of wound healing GO:0090303 1 0.017
neural crest cell differentiation GO:0014033 72 0.017
single organism localization GO:1902578 225 0.017
cellular ketone metabolic process GO:0042180 11 0.017
negative regulation of macromolecule metabolic process GO:0010605 76 0.017
neuroblast proliferation GO:0007405 2 0.017
regulation of establishment of protein localization GO:0070201 4 0.017
regulation of organ growth GO:0046620 3 0.017
ear development GO:0043583 127 0.017
bone remodeling GO:0046849 2 0.016
regulation of epithelial cell proliferation GO:0050678 3 0.016
inflammatory response GO:0006954 8 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
organelle organization GO:0006996 227 0.016
retinoic acid receptor signaling pathway GO:0048384 16 0.016
heart development GO:0007507 313 0.016
endothelial cell fate commitment GO:0060839 3 0.016
multi organism process GO:0051704 134 0.016
cellular hormone metabolic process GO:0034754 19 0.016
regulation of cell communication GO:0010646 232 0.016
regulation of cellular protein metabolic process GO:0032268 52 0.016
cellular amine metabolic process GO:0044106 2 0.016
specification of symmetry GO:0009799 204 0.016
regulation of hormone levels GO:0010817 21 0.016
reactive oxygen species metabolic process GO:0072593 6 0.016
organelle assembly GO:0070925 110 0.015
interspecies interaction between organisms GO:0044419 4 0.015
response to glucose GO:0009749 3 0.015
secondary metabolic process GO:0019748 3 0.015
angiogenesis GO:0001525 158 0.015
regulation of cell motility GO:2000145 46 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
regulation of protein transport GO:0051223 3 0.015
protein import GO:0017038 3 0.015
regulation of gtpase activity GO:0043087 2 0.015
gtp metabolic process GO:0046039 4 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.015
regulation of anatomical structure morphogenesis GO:0022603 130 0.015
response to biotic stimulus GO:0009607 97 0.015
carbohydrate biosynthetic process GO:0016051 1 0.015
behavior GO:0007610 74 0.015
axon development GO:0061564 166 0.015
xenobiotic metabolic process GO:0006805 4 0.015
negative regulation of cellular protein metabolic process GO:0032269 16 0.015
response to amino acid GO:0043200 2 0.014
negative regulation of defense response GO:0031348 2 0.014
positive regulation of cell activation GO:0050867 1 0.014
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.014
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
renal tubule morphogenesis GO:0061333 1 0.014
proteolysis GO:0006508 38 0.014
toxin metabolic process GO:0009404 1 0.014
negative regulation of apoptotic process GO:0043066 55 0.014
isoprenoid metabolic process GO:0006720 15 0.014
cellular protein modification process GO:0006464 100 0.014
macromolecule modification GO:0043412 111 0.014
positive regulation of biosynthetic process GO:0009891 68 0.014
regulation of body fluid levels GO:0050878 16 0.014
regulation of tissue remodeling GO:0034103 2 0.013
rna metabolic process GO:0016070 219 0.013
microtubule polymerization GO:0046785 2 0.013
axis elongation involved in somitogenesis GO:0090245 2 0.013
negative regulation of cellular biosynthetic process GO:0031327 55 0.013
positive regulation of map kinase activity GO:0043406 3 0.013
lipid metabolic process GO:0006629 52 0.013
antimicrobial humoral response GO:0019730 2 0.013
response to antibiotic GO:0046677 1 0.013
monocarboxylic acid biosynthetic process GO:0072330 12 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
cellular aldehyde metabolic process GO:0006081 4 0.013
negative regulation of multicellular organismal process GO:0051241 69 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
fatty acid metabolic process GO:0006631 5 0.013
positive regulation of multicellular organismal process GO:0051240 52 0.013
cell projection organization GO:0030030 284 0.013
blood circulation GO:0008015 87 0.013
small molecule catabolic process GO:0044282 3 0.013
reactive oxygen species biosynthetic process GO:1903409 1 0.013
response to amine GO:0014075 1 0.013
positive regulation of lipid metabolic process GO:0045834 1 0.013
mycotoxin metabolic process GO:0043385 1 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
somitogenesis GO:0001756 87 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
lipid catabolic process GO:0016042 4 0.013
muscle structure development GO:0061061 196 0.013
phagocytosis GO:0006909 3 0.013
positive regulation of response to stimulus GO:0048584 80 0.013
response to transition metal nanoparticle GO:1990267 28 0.012
regulation of collagen metabolic process GO:0010712 2 0.012
peptide transport GO:0015833 1 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
cellular response to steroid hormone stimulus GO:0071383 31 0.012
positive regulation of protein polymerization GO:0032273 2 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
nucleic acid metabolic process GO:0090304 244 0.012
positive regulation of secretion GO:0051047 1 0.012
mitochondrial transport GO:0006839 2 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.012
cellular response to unfolded protein GO:0034620 2 0.012
homeostasis of number of cells within a tissue GO:0048873 4 0.012
cerebellar granular layer formation GO:0021684 3 0.012
mitochondrion organization GO:0007005 4 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
central nervous system neuron differentiation GO:0021953 74 0.012
cellular component disassembly GO:0022411 1 0.012
fin morphogenesis GO:0033334 53 0.012
collagen biosynthetic process GO:0032964 2 0.012
hematopoietic stem cell migration GO:0035701 4 0.012
endocrine hormone secretion GO:0060986 2 0.012
multicellular organismal response to stress GO:0033555 2 0.012
Zebrafish
negative regulation of map kinase activity GO:0043407 2 0.012
regulation of bone remodeling GO:0046850 2 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
smooth muscle contraction GO:0006939 2 0.011
heart contraction GO:0060047 71 0.011
regulation of developmental process GO:0050793 247 0.011
regulation of cell migration GO:0030334 40 0.011
regulation of calcium ion transport GO:0051924 2 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.011
regulation of response to wounding GO:1903034 11 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.011
eye morphogenesis GO:0048592 144 0.011
Zebrafish
nuclear transport GO:0051169 4 0.011
regionalization GO:0003002 274 0.011
response to axon injury GO:0048678 14 0.011
single organism organelle organization GO:1902589 199 0.011
regulation of circadian rhythm GO:0042752 4 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
cellular component assembly GO:0022607 170 0.011
regulation of peptidase activity GO:0052547 23 0.011
regulation of binding GO:0051098 3 0.011
nuclear import GO:0051170 3 0.011
nerve development GO:0021675 45 0.011
intracellular signal transduction GO:0035556 85 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
positive regulation of jnk cascade GO:0046330 3 0.011
negative regulation of dna replication GO:0008156 2 0.011
regulation of response to oxidative stress GO:1902882 2 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.011
negative regulation of protein transport GO:0051224 3 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
protein import into nucleus GO:0006606 3 0.011
protein secretion GO:0009306 1 0.010
positive regulation of immune effector process GO:0002699 3 0.010
cellular response to decreased oxygen levels GO:0036294 1 0.010
ribonucleotide metabolic process GO:0009259 27 0.010
regulation of coagulation GO:0050818 2 0.010
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
regulation of blood pressure GO:0008217 1 0.010
hydrogen peroxide metabolic process GO:0042743 2 0.010
cellular response to starvation GO:0009267 1 0.010
cellular component maintenance GO:0043954 3 0.010
regulation of cellular component organization GO:0051128 86 0.010
positive regulation of inflammatory response GO:0050729 1 0.010
nephron epithelium morphogenesis GO:0072088 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
isoprenoid biosynthetic process GO:0008299 7 0.010
Zebrafish
determination of left right symmetry GO:0007368 179 0.010
regulation of gtp catabolic process GO:0033124 2 0.010
cell substrate adhesion GO:0031589 4 0.010
negative regulation of kinase activity GO:0033673 4 0.010

dhrs9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.099
inherited metabolic disorder DOID:655 0 0.094
immune system disease DOID:2914 0 0.050
disease of anatomical entity DOID:7 0 0.050
amino acid metabolic disorder DOID:9252 0 0.012