Danio rerio

16 known processes

ppp1cbl

protein phosphatase 1, catalytic subunit, beta isoform, like

(Aliases: Pp1alpha-96A,zgc:64169,wu:fa14b10)

ppp1cbl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cognition GO:0050890 1 0.175
regulation of organelle assembly GO:1902115 4 0.117
multicellular organism growth GO:0035264 4 0.105
positive regulation of cellular component biogenesis GO:0044089 3 0.099
central nervous system development GO:0007417 387 0.094
negative regulation of biological process GO:0048519 304 0.093
regulation of multicellular organismal development GO:2000026 223 0.093
vasculature development GO:0001944 278 0.089
segmentation GO:0035282 97 0.079
maintenance of location GO:0051235 4 0.076
regulation of oocyte development GO:0060281 3 0.072
hematopoietic or lymphoid organ development GO:0048534 191 0.071
immune system development GO:0002520 191 0.069
negative regulation of protein kinase activity GO:0006469 4 0.067
lipid storage GO:0019915 1 0.065
regionalization GO:0003002 274 0.063
aging GO:0007568 2 0.063
regulation of intracellular protein transport GO:0033157 3 0.062
meiotic nuclear division GO:0007126 4 0.061
pole plasm assembly GO:0007315 4 0.057
oocyte anterior posterior axis specification GO:0007314 4 0.056
nuclear export GO:0051168 1 0.055
blood vessel development GO:0001568 246 0.054
amine metabolic process GO:0009308 2 0.053
regulation of reproductive process GO:2000241 4 0.051
protein polymerization GO:0051258 4 0.051
regulation of metabolic process GO:0019222 359 0.050
regulation of multicellular organismal process GO:0051239 277 0.048
growth GO:0040007 174 0.048
positive regulation of secretion by cell GO:1903532 1 0.048
phagocytosis GO:0006909 3 0.047
maternal determination of anterior posterior axis embryo GO:0008358 4 0.047
regulation of response to stimulus GO:0048583 269 0.047
regulation of establishment of protein localization GO:0070201 4 0.046
immune system process GO:0002376 241 0.045
spermatid development GO:0007286 2 0.045
organelle localization GO:0051640 49 0.044
regulation of gene silencing GO:0060968 1 0.044
nuclear migration GO:0007097 3 0.043
regulation of synaptic plasticity GO:0048167 1 0.043
cell projection organization GO:0030030 284 0.042
oocyte development GO:0048599 14 0.042
regulation of cellular amino acid metabolic process GO:0006521 0 0.041
blood vessel morphogenesis GO:0048514 216 0.041
negative regulation of cellular catabolic process GO:0031330 3 0.041
gamete generation GO:0007276 33 0.040
locomotor rhythm GO:0045475 3 0.040
sensory perception of pain GO:0019233 1 0.038
signal transduction GO:0007165 455 0.038
peptidyl threonine phosphorylation GO:0018107 1 0.037
negative regulation of protein phosphorylation GO:0001933 4 0.037
rna localization GO:0006403 4 0.036
positive regulation of response to stimulus GO:0048584 80 0.036
somite development GO:0061053 96 0.035
organic cyclic compound biosynthetic process GO:1901362 223 0.035
organelle assembly GO:0070925 110 0.035
single fertilization GO:0007338 3 0.035
adherens junction organization GO:0034332 4 0.035
peptidyl serine phosphorylation GO:0018105 1 0.035
nucleocytoplasmic transport GO:0006913 4 0.034
nucleobase containing compound biosynthetic process GO:0034654 205 0.034
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.034
positive regulation of cellular catabolic process GO:0031331 3 0.034
mitotic cell cycle GO:0000278 64 0.034
oxidative phosphorylation GO:0006119 1 0.034
fertilization GO:0009566 3 0.034
nucleic acid templated transcription GO:0097659 181 0.033
regulation of protein targeting GO:1903533 2 0.033
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.033
response to external stimulus GO:0009605 264 0.033
positive regulation of transport GO:0051050 2 0.033
cytoplasm organization GO:0007028 4 0.033
anterior posterior pattern specification GO:0009952 152 0.033
stem cell proliferation GO:0072089 4 0.033
developmental process involved in reproduction GO:0003006 27 0.032
negative regulation of map kinase activity GO:0043407 2 0.032
negative regulation of catabolic process GO:0009895 3 0.032
i kappab kinase nf kappab signaling GO:0007249 4 0.032
peptidyl serine modification GO:0018209 2 0.032
regulation of signaling GO:0023051 235 0.031
synaptic growth at neuromuscular junction GO:0051124 2 0.031
mitochondrion organization GO:0007005 4 0.031
larval development GO:0002164 2 0.031
regulation of protein ubiquitination GO:0031396 3 0.031
germ cell development GO:0007281 22 0.030
protein secretion GO:0009306 1 0.030
cellular nitrogen compound biosynthetic process GO:0044271 218 0.030
meiotic chromosome segregation GO:0045132 3 0.030
synaptic vesicle recycling GO:0036465 1 0.030
ubiquitin dependent protein catabolic process GO:0006511 3 0.030
cell death GO:0008219 121 0.029
gtp catabolic process GO:0006184 2 0.029
nuclear transport GO:0051169 4 0.029
regulation of signal transduction GO:0009966 225 0.029
regulation of receptor activity GO:0010469 2 0.029
regulation of cellular amine metabolic process GO:0033238 0 0.029
regulation of protein binding GO:0043393 3 0.029
aromatic compound biosynthetic process GO:0019438 217 0.029
b cell differentiation GO:0030183 1 0.028
negative regulation of kinase activity GO:0033673 4 0.028
regulation of binding GO:0051098 3 0.028
hemopoiesis GO:0030097 183 0.027
optic placode formation involved in camera type eye formation GO:0046619 3 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.027
neuroblast proliferation GO:0007405 2 0.027
positive regulation of cell activation GO:0050867 1 0.026
establishment of protein localization to organelle GO:0072594 4 0.026
positive regulation of stress activated mapk cascade GO:0032874 3 0.026
actin filament polymerization GO:0030041 2 0.026
multi organism process GO:0051704 134 0.025
cellular macromolecule metabolic process GO:0044260 391 0.025
regulation of protein transport GO:0051223 3 0.025
intracellular signal transduction GO:0035556 85 0.025
single organism organelle organization GO:1902589 199 0.025
establishment of localization GO:0051234 244 0.025
membrane fusion GO:0061025 2 0.025
negative regulation of mapk cascade GO:0043409 4 0.025
guanosine containing compound metabolic process GO:1901068 4 0.025
positive regulation of catabolic process GO:0009896 4 0.025
cilium morphogenesis GO:0060271 85 0.024
cytokinesis GO:0000910 3 0.024
sexual reproduction GO:0019953 36 0.024
cell projection morphogenesis GO:0048858 244 0.024
optic nerve development GO:0021554 15 0.024
single organism reproductive process GO:0044702 40 0.024
negative regulation of cellular process GO:0048523 283 0.024
regulation of developmental process GO:0050793 247 0.024
cellular amine metabolic process GO:0044106 2 0.024
regulation of cell projection assembly GO:0060491 4 0.024
pronuclear migration GO:0035046 1 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
negative regulation of protein complex assembly GO:0031333 1 0.023
angiogenesis GO:0001525 158 0.023
cellular biosynthetic process GO:0044249 286 0.023
regulation of gene expression GO:0010468 265 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
organic cyclic compound metabolic process GO:1901360 301 0.023
regulation of cytokine production GO:0001817 3 0.023
peptidyl threonine modification GO:0018210 1 0.023
developmental growth GO:0048589 166 0.023
positive regulation of biological process GO:0048518 253 0.022
modification dependent macromolecule catabolic process GO:0043632 3 0.022
cellular nitrogen compound metabolic process GO:0034641 290 0.022
guanosine containing compound catabolic process GO:1901069 2 0.022
gtp metabolic process GO:0046039 4 0.022
regulation of synapse organization GO:0050807 3 0.022
death GO:0016265 121 0.022
cellular protein modification process GO:0006464 100 0.022
protein polyubiquitination GO:0000209 4 0.022
stem cell maintenance GO:0019827 4 0.021
gene expression GO:0010467 252 0.021
regulation of biological quality GO:0065008 263 0.021
positive regulation of cellular amine metabolic process GO:0033240 0 0.021
heterocycle metabolic process GO:0046483 290 0.021
regulation of autophagy GO:0010506 3 0.021
regulation of cell communication GO:0010646 232 0.021
regulation of purine nucleotide catabolic process GO:0033121 2 0.021
stem cell division GO:0017145 1 0.021
phototransduction GO:0007602 2 0.020
cellular response to external stimulus GO:0071496 2 0.020
cellular ketone metabolic process GO:0042180 11 0.020
somatic muscle development GO:0007525 4 0.020
nitrogen compound metabolic process GO:0006807 319 0.020
somitogenesis GO:0001756 87 0.020
dorsal ventral pattern formation GO:0009953 125 0.020
multicellular organism reproduction GO:0032504 35 0.020
phosphorus metabolic process GO:0006793 109 0.020
protein acetylation GO:0006473 2 0.020
actin polymerization or depolymerization GO:0008154 2 0.020
negative regulation of response to stimulus GO:0048585 104 0.020
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.020
cell substrate adhesion GO:0031589 4 0.020
regulation of cell development GO:0060284 100 0.019
chordate embryonic development GO:0043009 271 0.019
meiosis i GO:0007127 1 0.019
nitric oxide biosynthetic process GO:0006809 2 0.019
cellular amide metabolic process GO:0043603 4 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.019
single organism membrane fusion GO:0044801 2 0.019
cellular carbohydrate metabolic process GO:0044262 4 0.019
nucleobase containing compound metabolic process GO:0006139 274 0.019
extrinsic apoptotic signaling pathway GO:0097191 3 0.019
protein import GO:0017038 3 0.018
regulation of exocytosis GO:0017157 1 0.018
cortical actin cytoskeleton organization GO:0030866 1 0.018
autophagy GO:0006914 4 0.018
regulation of molecular function GO:0065009 70 0.018
regulation of protein catabolic process GO:0042176 1 0.018
macromolecule modification GO:0043412 111 0.018
protein acylation GO:0043543 3 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
neuromuscular synaptic transmission GO:0007274 2 0.018
b cell activation GO:0042113 2 0.018
regulation of protein complex assembly GO:0043254 3 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.018
developmental growth involved in morphogenesis GO:0060560 86 0.018
positive regulation of jnk cascade GO:0046330 3 0.018
negative regulation of catalytic activity GO:0043086 21 0.017
negative regulation of protein transport GO:0051224 3 0.017
nephron tubule morphogenesis GO:0072078 1 0.017
regulation of cellular component organization GO:0051128 86 0.017
protein metabolic process GO:0019538 183 0.017
positive regulation of stem cell proliferation GO:2000648 1 0.017
erk1 and erk2 cascade GO:0070371 4 0.017
regulation of cellular protein catabolic process GO:1903362 1 0.017
regulation of protein depolymerization GO:1901879 1 0.017
cell motility GO:0048870 244 0.017
spermatid differentiation GO:0048515 2 0.017
positive regulation of secretion GO:0051047 1 0.017
regulation of dendrite morphogenesis GO:0048814 3 0.017
dorsal ventral neural tube patterning GO:0021904 1 0.017
regulation of cell shape GO:0008360 1 0.017
rna metabolic process GO:0016070 219 0.016
single organism localization GO:1902578 225 0.016
cellular aromatic compound metabolic process GO:0006725 295 0.016
spindle assembly involved in meiosis GO:0090306 1 0.016
adult behavior GO:0030534 2 0.016
rna 3 end processing GO:0031123 2 0.016
regulation of transcription dna templated GO:0006355 213 0.016
steroid hormone secretion GO:0035929 1 0.016
regulation of mrna processing GO:0050684 3 0.016
positive regulation of cellular process GO:0048522 201 0.016
response to stress GO:0006950 263 0.016
regulation of protein polymerization GO:0032271 2 0.016
cellular transition metal ion homeostasis GO:0046916 3 0.016
phosphorylation GO:0016310 69 0.016
protein modification process GO:0036211 100 0.016
lateral inhibition GO:0046331 1 0.016
establishment of rna localization GO:0051236 3 0.016
macromolecular complex disassembly GO:0032984 1 0.016
neuron development GO:0048666 262 0.015
renal tubule morphogenesis GO:0061333 1 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
heterocycle biosynthetic process GO:0018130 215 0.015
regulation of jak stat cascade GO:0046425 3 0.015
female meiotic division GO:0007143 2 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.015
protein complex disassembly GO:0043241 1 0.015
protein targeting to nucleus GO:0044744 3 0.015
regulation of intracellular signal transduction GO:1902531 57 0.015
localization of cell GO:0051674 244 0.015
pathway restricted smad protein phosphorylation GO:0060389 1 0.015
meiotic cell cycle process GO:1903046 3 0.015
germ line stem cell maintenance GO:0030718 2 0.015
nucleoside triphosphate biosynthetic process GO:0009142 2 0.015
single organism transport GO:0044765 206 0.015
phagocytosis engulfment GO:0006911 1 0.015
nuclear import GO:0051170 3 0.015
regulation of nitrogen compound metabolic process GO:0051171 251 0.015
cellular response to nutrient levels GO:0031669 2 0.015
organelle organization GO:0006996 227 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.015
regulation of cell maturation GO:1903429 1 0.015
polyol metabolic process GO:0019751 1 0.015
cellular component disassembly GO:0022411 1 0.015
wnt signaling pathway GO:0016055 80 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
negative regulation of wnt signaling pathway GO:0030178 30 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
multi organism reproductive process GO:0044703 36 0.015
system process GO:0003008 185 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
cellular localization GO:0051641 97 0.014
compound eye development GO:0048749 2 0.014
gene silencing by mirna GO:0035195 3 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.014
keratinocyte differentiation GO:0030216 0 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
tube closure GO:0060606 1 0.014
regulation of macromolecule metabolic process GO:0060255 317 0.014
canonical wnt signaling pathway GO:0060070 48 0.014
regulation of reactive oxygen species metabolic process GO:2000377 2 0.014
female gamete generation GO:0007292 14 0.014
regulation of production of molecular mediator of immune response GO:0002700 1 0.014
exocytosis GO:0006887 1 0.014
cell aging GO:0007569 2 0.014
response to drug GO:0042493 3 0.014
single organism biosynthetic process GO:0044711 71 0.014
digestive system development GO:0055123 289 0.014
protein targeting to membrane GO:0006612 1 0.014
negative regulation of protein localization to nucleus GO:1900181 2 0.014
negative regulation of metabolic process GO:0009892 86 0.013
negative regulation of signaling GO:0023057 96 0.013
head development GO:0060322 303 0.013
spindle assembly GO:0051225 2 0.013
multicellular organismal reproductive process GO:0048609 35 0.013
membrane invagination GO:0010324 1 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
positive regulation of cell adhesion GO:0045785 1 0.013
cell migration GO:0016477 237 0.013
lamellipodium assembly GO:0030032 1 0.013
ribosome assembly GO:0042255 1 0.013
neurotransmitter transport GO:0006836 2 0.013
neurological system process GO:0050877 62 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
secondary metabolic process GO:0019748 3 0.013
positive regulation of multicellular organismal process GO:0051240 52 0.013
cell cycle GO:0007049 93 0.013
cell morphogenesis GO:0000902 289 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
primary neural tube formation GO:0014020 1 0.013
regulation of epithelial cell proliferation GO:0050678 3 0.013
organophosphate biosynthetic process GO:0090407 23 0.013
germ line stem cell division GO:0042078 1 0.013
protein localization to plasma membrane GO:0072659 1 0.013
regulation of protein complex disassembly GO:0043244 1 0.013
muscle structure development GO:0061061 196 0.013
response to biotic stimulus GO:0009607 97 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
positive regulation of leukocyte differentiation GO:1902107 1 0.012
regulation of cell projection organization GO:0031344 44 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
protein complex localization GO:0031503 1 0.012
gene silencing by rna GO:0031047 4 0.012
negative regulation of gene silencing GO:0060969 1 0.012
regulation of gene silencing by rna GO:0060966 1 0.012
regulation of cell death GO:0010941 103 0.012
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.012
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.012
negative regulation of multicellular organismal process GO:0051241 69 0.012
cilium organization GO:0044782 71 0.012
regulation of organ growth GO:0046620 3 0.012
oxoacid metabolic process GO:0043436 31 0.012
cellular component biogenesis GO:0044085 178 0.012
carbohydrate biosynthetic process GO:0016051 1 0.012
cell projection assembly GO:0030031 64 0.012
regulation of synapse assembly GO:0051963 3 0.012
positive regulation of immune effector process GO:0002699 3 0.012
posttranscriptional gene silencing by rna GO:0035194 3 0.012
developmental programmed cell death GO:0010623 4 0.012
positive regulation of neuron death GO:1901216 1 0.012
internal peptidyl lysine acetylation GO:0018393 2 0.012
negative regulation of cytokine production GO:0001818 1 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
regulation of erythrocyte differentiation GO:0045646 2 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
regulation of lipid transport GO:0032368 4 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
regulation of circadian rhythm GO:0042752 4 0.012
embryonic limb morphogenesis GO:0030326 2 0.012
cortical cytoskeleton organization GO:0030865 1 0.012
dicarboxylic acid transport GO:0006835 1 0.012
negative regulation of epithelial cell proliferation GO:0050680 1 0.012
cell matrix adhesion GO:0007160 4 0.012
heart development GO:0007507 313 0.012
epiboly GO:0090504 41 0.012
nucleic acid transport GO:0050657 2 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
regulation of cellular protein metabolic process GO:0032268 52 0.011
positive regulation of muscle cell differentiation GO:0051149 1 0.011
cell surface receptor signaling pathway GO:0007166 325 0.011
regulation of dendrite development GO:0050773 3 0.011
positive regulation of exocytosis GO:0045921 1 0.011
locomotion GO:0040011 313 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
p38mapk cascade GO:0038066 1 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
protein dephosphorylation GO:0006470 3 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
protein localization GO:0008104 40 0.011
nucleotide biosynthetic process GO:0009165 21 0.011
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.011
cellular component assembly GO:0022607 170 0.011
regulation of ras gtpase activity GO:0032318 2 0.011
regulation of mesenchymal cell proliferation GO:0010464 1 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
mitotic nuclear division GO:0007067 18 0.011
nik nf kappab signaling GO:0038061 1 0.011
negative regulation of programmed cell death GO:0043069 58 0.011
positive regulation of synapse assembly GO:0051965 1 0.011
negative regulation of secretion GO:0051048 2 0.011
cell proliferation GO:0008283 80 0.011
posttranscriptional gene silencing GO:0016441 3 0.011
response to uv GO:0009411 3 0.011
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.011
developmental maturation GO:0021700 34 0.011
regulation of cell activation GO:0050865 1 0.011
synapsis GO:0007129 1 0.011
nephron epithelium morphogenesis GO:0072088 1 0.011
rna transport GO:0050658 2 0.011
macroautophagy GO:0016236 1 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
regulation of gtpase activity GO:0043087 2 0.011
proximal distal pattern formation GO:0009954 1 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
response to other organism GO:0051707 97 0.011
gene silencing GO:0016458 4 0.011
cell part morphogenesis GO:0032990 246 0.011
regulation of establishment or maintenance of cell polarity GO:0032878 2 0.011
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.011
nucleic acid metabolic process GO:0090304 244 0.011
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.010
photoreceptor cell maintenance GO:0045494 11 0.010
single organism nuclear import GO:1902593 3 0.010
regulation of cell differentiation GO:0045595 142 0.010
neurotransmitter secretion GO:0007269 2 0.010
regulation of neurotransmitter transport GO:0051588 1 0.010
reproductive process GO:0022414 40 0.010
internal protein amino acid acetylation GO:0006475 2 0.010
rna biosynthetic process GO:0032774 181 0.010
regulation of wnt signaling pathway GO:0030111 53 0.010
regulation of protein import into nucleus GO:0042306 2 0.010
protein import into nucleus GO:0006606 3 0.010
carboxylic acid metabolic process GO:0019752 22 0.010
positive regulation of dna metabolic process GO:0051054 1 0.010
axis specification GO:0009798 43 0.010
cytoskeleton dependent cytokinesis GO:0061640 3 0.010
regulation of response to biotic stimulus GO:0002831 2 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.010
response to chemical GO:0042221 320 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.010
brain development GO:0007420 293 0.010
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.010

ppp1cbl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
disease of cellular proliferation DOID:14566 0 0.019
cancer DOID:162 0 0.018
organ system cancer DOID:0050686 0 0.013
musculoskeletal system disease DOID:17 0 0.013