Danio rerio

0 known processes

arhgef25b

Rho guanine nucleotide exchange factor (GEF) 25b

(Aliases: im:7156160)

arhgef25b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cellular component biogenesis GO:0044089 3 0.179
Worm
larval development GO:0002164 2 0.078
aging GO:0007568 2 0.066
regulation of multicellular organismal development GO:2000026 223 0.064
Worm
cognition GO:0050890 1 0.062
maintenance of location GO:0051235 4 0.060
regulation of synapse organization GO:0050807 3 0.059
synaptic growth at neuromuscular junction GO:0051124 2 0.057
regulation of synapse assembly GO:0051963 3 0.053
regulation of cell projection assembly GO:0060491 4 0.051
positive regulation of transport GO:0051050 2 0.048
positive regulation of biological process GO:0048518 253 0.047
Worm
signal transduction GO:0007165 455 0.047
regulation of biological quality GO:0065008 263 0.045
Worm
regulation of cell substrate adhesion GO:0010810 1 0.044
cellular amine metabolic process GO:0044106 2 0.044
amine metabolic process GO:0009308 2 0.043
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.042
regulation of developmental process GO:0050793 247 0.041
Worm
regulation of establishment of protein localization GO:0070201 4 0.041
cell morphogenesis GO:0000902 289 0.040
Worm
positive regulation of cellular catabolic process GO:0031331 3 0.040
Worm
lipid storage GO:0019915 1 0.038
regulation of filopodium assembly GO:0051489 2 0.038
multicellular organism growth GO:0035264 4 0.037
Worm
regulation of cellular amine metabolic process GO:0033238 0 0.036
regulation of protein complex assembly GO:0043254 3 0.035
Worm
immune system process GO:0002376 241 0.035
embryonic organ development GO:0048568 381 0.034
regulation of binding GO:0051098 3 0.033
cellular component biogenesis GO:0044085 178 0.033
Worm
digestive tract development GO:0048565 265 0.033
establishment of protein localization to organelle GO:0072594 4 0.032
response to hexose GO:0009746 3 0.032
regulation of cellular amino acid metabolic process GO:0006521 0 0.032
cellular ketone metabolic process GO:0042180 11 0.032
cell substrate adhesion GO:0031589 4 0.031
positive regulation of protein complex assembly GO:0031334 2 0.031
Worm
regulation of signal transduction GO:0009966 225 0.031
Worm
cell projection organization GO:0030030 284 0.031
Worm
single organism organelle organization GO:1902589 199 0.031
Worm
morphogenesis of an epithelium GO:0002009 333 0.030
neurotransmitter secretion GO:0007269 2 0.030
cellular component assembly GO:0022607 170 0.030
Worm
regulation of cytoplasmic transport GO:1903649 4 0.030
protein localization to nucleus GO:0034504 3 0.030
autophagy GO:0006914 4 0.029
gtp metabolic process GO:0046039 4 0.029
Worm
leukocyte proliferation GO:0070661 1 0.029
actin polymerization or depolymerization GO:0008154 2 0.029
Worm
regulation of cell activation GO:0050865 1 0.029
cellular component movement GO:0006928 335 0.029
Worm
protein import GO:0017038 3 0.029
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.028
response to external stimulus GO:0009605 264 0.028
Worm
angiogenesis GO:0001525 158 0.028
response to chemical GO:0042221 320 0.027
Worm
adherens junction organization GO:0034332 4 0.027
nuclear transport GO:0051169 4 0.027
protein import into nucleus GO:0006606 3 0.027
cell migration GO:0016477 237 0.027
Worm
digestive system development GO:0055123 289 0.026
cell motility GO:0048870 244 0.026
Worm
cellular macromolecule metabolic process GO:0044260 391 0.026
nucleocytoplasmic transport GO:0006913 4 0.026
protein secretion GO:0009306 1 0.026
cell matrix adhesion GO:0007160 4 0.026
positive regulation of cytoskeleton organization GO:0051495 3 0.025
Worm
regulation of protein transport GO:0051223 3 0.025
secondary metabolic process GO:0019748 3 0.025
protein metabolic process GO:0019538 183 0.025
Worm
single organism nuclear import GO:1902593 3 0.025
oxoacid metabolic process GO:0043436 31 0.025
gtp catabolic process GO:0006184 2 0.025
Worm
cellular response to external stimulus GO:0071496 2 0.024
muscle organ development GO:0007517 101 0.024
carboxylic acid metabolic process GO:0019752 22 0.024
amino acid transport GO:0006865 2 0.024
digestive tract morphogenesis GO:0048546 231 0.024
organic acid metabolic process GO:0006082 31 0.024
stem cell maintenance GO:0019827 4 0.023
positive regulation of cellular process GO:0048522 201 0.023
Worm
brain development GO:0007420 293 0.023
protein targeting to nucleus GO:0044744 3 0.023
muscle structure development GO:0061061 196 0.023
cell substrate junction assembly GO:0007044 2 0.023
vasculature development GO:0001944 278 0.023
cellular response to nutrient levels GO:0031669 2 0.023
nucleobase containing compound metabolic process GO:0006139 274 0.022
Worm
locomotion GO:0040011 313 0.022
Worm
positive regulation of secretion GO:0051047 1 0.022
membrane fusion GO:0061025 2 0.022
mononuclear cell proliferation GO:0032943 1 0.022
positive regulation of catabolic process GO:0009896 4 0.022
Worm
central nervous system development GO:0007417 387 0.022
regulation of cell shape GO:0008360 1 0.021
response to drug GO:0042493 3 0.021
neurotransmitter transport GO:0006836 2 0.021
regulation of protein targeting GO:1903533 2 0.021
protein heterooligomerization GO:0051291 1 0.021
regulation of cytokine production GO:0001817 3 0.021
eye development GO:0001654 277 0.021
regulation of response to stimulus GO:0048583 269 0.021
Worm
regulation of intracellular protein transport GO:0033157 3 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
regulation of multicellular organism growth GO:0040014 4 0.021
Worm
regulation of nucleotide catabolic process GO:0030811 2 0.020
Worm
establishment of protein localization to plasma membrane GO:0090002 1 0.020
positive regulation of immune effector process GO:0002699 3 0.020
cell surface receptor signaling pathway GO:0007166 325 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
Worm
cellular nitrogen compound metabolic process GO:0034641 290 0.020
Worm
positive regulation of cell cycle GO:0045787 3 0.020
multi organism process GO:0051704 134 0.020
Worm
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.020
guanosine containing compound catabolic process GO:1901069 2 0.020
Worm
meiotic cell cycle process GO:1903046 3 0.020
positive regulation of cell activation GO:0050867 1 0.020
cellular response to chemical stimulus GO:0070887 157 0.019
localization of cell GO:0051674 244 0.019
Worm
blood vessel development GO:0001568 246 0.019
nitrogen compound metabolic process GO:0006807 319 0.019
Worm
regulation of wound healing GO:0061041 2 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
Worm
tube morphogenesis GO:0035239 349 0.019
camera type eye development GO:0043010 222 0.019
positive regulation of secretion by cell GO:1903532 1 0.019
actin filament based process GO:0030029 64 0.019
Worm
cytokinesis GO:0000910 3 0.019
Worm
regulation of signaling GO:0023051 235 0.019
Worm
stem cell proliferation GO:0072089 4 0.019
regulation of cellular metabolic process GO:0031323 320 0.019
Worm
regulation of protein import into nucleus GO:0042306 2 0.019
organic substance biosynthetic process GO:1901576 289 0.019
regulation of nucleoside metabolic process GO:0009118 2 0.019
Worm
developmental growth GO:0048589 166 0.019
Worm
positive regulation of cell adhesion GO:0045785 1 0.019
cellular response to starvation GO:0009267 1 0.019
sensory organ development GO:0007423 393 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
protein localization to plasma membrane GO:0072659 1 0.018
response to external biotic stimulus GO:0043207 97 0.018
protein polymerization GO:0051258 4 0.018
Worm
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
small molecule metabolic process GO:0044281 77 0.018
Worm
meiotic nuclear division GO:0007126 4 0.018
positive regulation of synapse assembly GO:0051965 1 0.018
nuclear import GO:0051170 3 0.018
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
organelle organization GO:0006996 227 0.018
Worm
regulation of macromolecule metabolic process GO:0060255 317 0.018
cellular amide metabolic process GO:0043603 4 0.018
regulation of metabolic process GO:0019222 359 0.018
Worm
cell death GO:0008219 121 0.018
heterocycle metabolic process GO:0046483 290 0.018
Worm
lymphocyte proliferation GO:0046651 1 0.017
embryo development ending in birth or egg hatching GO:0009792 271 0.017
Worm
response to carbohydrate GO:0009743 3 0.017
regulation of gene expression GO:0010468 265 0.017
actin cytoskeleton organization GO:0030036 63 0.017
Worm
regulation of blood vessel size GO:0050880 2 0.017
regulation of reproductive process GO:2000241 4 0.017
mitochondrion organization GO:0007005 4 0.017
regulation of protein localization to nucleus GO:1900180 2 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
regulation of stem cell differentiation GO:2000736 4 0.017
response to stress GO:0006950 263 0.017
gastrulation GO:0007369 208 0.017
carbohydrate homeostasis GO:0033500 1 0.017
biosynthetic process GO:0009058 294 0.017
cellular component morphogenesis GO:0032989 336 0.017
Worm
negative regulation of cellular process GO:0048523 283 0.017
single organism metabolic process GO:0044710 217 0.016
Worm
negative regulation of biological process GO:0048519 304 0.016
regulation of neurotransmitter transport GO:0051588 1 0.016
regulation of nervous system development GO:0051960 90 0.016
Worm
gene expression GO:0010467 252 0.016
growth GO:0040007 174 0.016
Worm
regulation of cell death GO:0010941 103 0.016
peptide transport GO:0015833 1 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
generation of neurons GO:0048699 385 0.016
Worm
negative regulation of protein transport GO:0051224 3 0.016
response to biotic stimulus GO:0009607 97 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
regulation of neurotransmitter secretion GO:0046928 1 0.016
sensory organ morphogenesis GO:0090596 200 0.016
adult behavior GO:0030534 2 0.016
transport GO:0006810 220 0.016
Worm
axonogenesis GO:0007409 152 0.016
Worm
regulation of rho protein signal transduction GO:0035023 2 0.016
Worm
regulation of autophagy GO:0010506 3 0.015
ventricular cardiac muscle tissue development GO:0003229 3 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
regionalization GO:0003002 274 0.015
cellular component disassembly GO:0022411 1 0.015
phagocytosis GO:0006909 3 0.015
Worm
regulation of cell differentiation GO:0045595 142 0.015
Worm
regulation of anatomical structure morphogenesis GO:0022603 130 0.015
Worm
connective tissue development GO:0061448 99 0.015
gland development GO:0048732 143 0.015
response to monosaccharide GO:0034284 3 0.015
spermatid development GO:0007286 2 0.015
mesenchyme development GO:0060485 127 0.015
regulation of nitrogen compound metabolic process GO:0051171 251 0.015
Worm
cell part morphogenesis GO:0032990 246 0.015
Worm
negative regulation of kinase activity GO:0033673 4 0.015
regulation of muscle contraction GO:0006937 3 0.015
regulation of apoptotic process GO:0042981 98 0.015
response to xenobiotic stimulus GO:0009410 45 0.015
regulation of cell communication GO:0010646 232 0.015
Worm
positive regulation of cell matrix adhesion GO:0001954 1 0.015
regulation of inflammatory response GO:0050727 2 0.015
regulation of macromolecule biosynthetic process GO:0010556 225 0.015
negative regulation of defense response GO:0031348 2 0.014
neuron differentiation GO:0030182 353 0.014
Worm
mitochondrial transport GO:0006839 2 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
macromolecule biosynthetic process GO:0009059 227 0.014
wound healing GO:0042060 90 0.014
synaptic vesicle localization GO:0097479 1 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
cellular protein catabolic process GO:0044257 4 0.014
response to alkaloid GO:0043279 2 0.014
heart development GO:0007507 313 0.014
regulation of gtpase activity GO:0043087 2 0.014
Worm
regulation of protein catabolic process GO:0042176 1 0.014
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
Worm
cellular biosynthetic process GO:0044249 286 0.014
neuron projection morphogenesis GO:0048812 161 0.014
Worm
regulation of blood pressure GO:0008217 1 0.014
head development GO:0060322 303 0.014
death GO:0016265 121 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
maternal determination of anterior posterior axis embryo GO:0008358 4 0.014
protein acetylation GO:0006473 2 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
b cell activation GO:0042113 2 0.014
single organism transport GO:0044765 206 0.014
Worm
response to corticosteroid GO:0031960 1 0.014
regulation of tube size GO:0035150 2 0.014
organelle fusion GO:0048284 3 0.014
regulation of dendrite development GO:0050773 3 0.013
inositol lipid mediated signaling GO:0048017 2 0.013
regulation of primary metabolic process GO:0080090 311 0.013
Worm
response to other organism GO:0051707 97 0.013
response to amino acid GO:0043200 2 0.013
chemosensory behavior GO:0007635 1 0.013
response to glucose GO:0009749 3 0.013
synaptic vesicle transport GO:0048489 1 0.013
internal protein amino acid acetylation GO:0006475 2 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
muscle tissue development GO:0060537 110 0.013
neuron neuron synaptic transmission GO:0007270 1 0.013
muscle cell development GO:0055001 115 0.013
spermatid differentiation GO:0048515 2 0.013
cellular protein modification process GO:0006464 100 0.013
single organism localization GO:1902578 225 0.013
Worm
cellular nitrogen compound biosynthetic process GO:0044271 218 0.013
protein modification process GO:0036211 100 0.013
collagen fibril organization GO:0030199 1 0.013
glucose homeostasis GO:0042593 1 0.013
muscle cell differentiation GO:0042692 139 0.013
regulation of response to biotic stimulus GO:0002831 2 0.013
nuclear migration GO:0007097 3 0.013
cortical cytoskeleton organization GO:0030865 1 0.013
establishment of localization GO:0051234 244 0.013
Worm
neuron projection development GO:0031175 180 0.013
Worm
response to nutrient GO:0007584 3 0.013
apoptotic process GO:0006915 116 0.013
cell projection morphogenesis GO:0048858 244 0.013
Worm
nucleic acid metabolic process GO:0090304 244 0.013
multi organism cellular process GO:0044764 2 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
macromolecule modification GO:0043412 111 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
Worm
macroautophagy GO:0016236 1 0.012
fatty acid biosynthetic process GO:0006633 4 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
response to wounding GO:0009611 116 0.012
cellular protein metabolic process GO:0044267 129 0.012
cellular response to xenobiotic stimulus GO:0071466 35 0.012
cellular response to oxygen levels GO:0071453 1 0.012
homeostatic process GO:0042592 142 0.012
cellular aromatic compound metabolic process GO:0006725 295 0.012
Worm
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
Worm
blood vessel morphogenesis GO:0048514 216 0.012
exocytosis GO:0006887 1 0.012
rna localization GO:0006403 4 0.012
interspecies interaction between organisms GO:0044419 4 0.012
axon development GO:0061564 166 0.012
Worm
membrane invagination GO:0010324 1 0.012
Worm
regulation of programmed cell death GO:0043067 101 0.012
protein acylation GO:0043543 3 0.012
regulation of mrna processing GO:0050684 3 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
Worm
internal peptidyl lysine acetylation GO:0018393 2 0.012
atp catabolic process GO:0006200 4 0.012
defense response to fungus GO:0050832 2 0.012
intracellular mrna localization GO:0008298 1 0.012
specification of symmetry GO:0009799 204 0.012
eye morphogenesis GO:0048592 144 0.012
regulation of cell matrix adhesion GO:0001952 1 0.012
negative regulation of cytoplasmic transport GO:1903650 2 0.012
cell projection assembly GO:0030031 64 0.012
neuron development GO:0048666 262 0.012
Worm
determination of bilateral symmetry GO:0009855 204 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
striated muscle cell development GO:0055002 108 0.011
single organism membrane fusion GO:0044801 2 0.011
system process GO:0003008 185 0.011
female sex differentiation GO:0046660 4 0.011
transmembrane transport GO:0055085 120 0.011
macromolecular complex disassembly GO:0032984 1 0.011
ion transport GO:0006811 114 0.011
synaptic transmission cholinergic GO:0007271 4 0.011
defense response GO:0006952 47 0.011
protein stabilization GO:0050821 2 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
glycoprotein metabolic process GO:0009100 23 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
regulation of metal ion transport GO:0010959 4 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
Worm
peptidyl threonine phosphorylation GO:0018107 1 0.011
negative regulation of cytokine production GO:0001818 1 0.011
regulation of cellular component organization GO:0051128 86 0.011
Worm
regulation of cell development GO:0060284 100 0.011
Worm
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
somatic muscle development GO:0007525 4 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
regulation of biosynthetic process GO:0009889 250 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
rna metabolic process GO:0016070 219 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
Worm
regulation of protein polymerization GO:0032271 2 0.011
Worm
protein dephosphorylation GO:0006470 3 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
programmed cell death GO:0012501 119 0.011
small molecule catabolic process GO:0044282 3 0.011
protein complex disassembly GO:0043241 1 0.011
positive regulation of protein polymerization GO:0032273 2 0.011
Worm
germ line stem cell maintenance GO:0030718 2 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
cytoplasm organization GO:0007028 4 0.011
intracellular signal transduction GO:0035556 85 0.011
ameboidal type cell migration GO:0001667 143 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
peptidyl serine modification GO:0018209 2 0.011
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.011
immune system development GO:0002520 191 0.011
cellular component maintenance GO:0043954 3 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
Worm
developmental programmed cell death GO:0010623 4 0.011
response to transition metal nanoparticle GO:1990267 28 0.010
regeneration GO:0031099 91 0.010
regulation of reactive oxygen species metabolic process GO:2000377 2 0.010
actin filament polymerization GO:0030041 2 0.010
Worm
organic cyclic compound biosynthetic process GO:1901362 223 0.010
regulation of sodium ion transport GO:0002028 2 0.010
protein homooligomerization GO:0051260 3 0.010
positive regulation of cell substrate adhesion GO:0010811 1 0.010
alcohol biosynthetic process GO:0046165 2 0.010
anterior posterior pattern specification GO:0009952 152 0.010
transcription dna templated GO:0006351 181 0.010
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.010
positive regulation of response to stimulus GO:0048584 80 0.010
lipid homeostasis GO:0055088 3 0.010
phagocytosis engulfment GO:0006911 1 0.010
Worm
antimicrobial humoral response GO:0019730 2 0.010
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.010
negative regulation of ras protein signal transduction GO:0046580 1 0.010
camera type eye morphogenesis GO:0048593 108 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010
i kappab kinase nf kappab signaling GO:0007249 4 0.010
response to uv GO:0009411 3 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.010
regulation of rna biosynthetic process GO:2001141 213 0.010
immunoglobulin mediated immune response GO:0016064 3 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010
Worm

arhgef25b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.059
musculoskeletal system disease DOID:17 0 0.019
nervous system disease DOID:863 0 0.014
disease of metabolism DOID:0014667 0 0.012
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
myopathy DOID:423 0 0.011
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011