Danio rerio

62 known processes

vox

ventral homeobox

(Aliases: zgc:136532,vega1,MGC136532)

vox biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular aromatic compound metabolic process GO:0006725 295 0.933
cellular biosynthetic process GO:0044249 286 0.911
tube morphogenesis GO:0035239 349 0.902
nucleobase containing compound metabolic process GO:0006139 274 0.883
regulation of metabolic process GO:0019222 359 0.874
organic cyclic compound metabolic process GO:1901360 301 0.864
signal transduction GO:0007165 455 0.849
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.838
regulation of primary metabolic process GO:0080090 311 0.819
regulation of mesoderm development GO:2000380 11 0.809
heterocycle metabolic process GO:0046483 290 0.808
regulation of macromolecule biosynthetic process GO:0010556 225 0.804
mesoderm formation GO:0001707 43 0.797
aromatic compound biosynthetic process GO:0019438 217 0.763
organic substance biosynthetic process GO:1901576 289 0.704
heart jogging GO:0003146 40 0.680
bmp signaling pathway GO:0030509 52 0.668
biosynthetic process GO:0009058 294 0.630
organic cyclic compound biosynthetic process GO:1901362 223 0.597
cellular macromolecule metabolic process GO:0044260 391 0.594
cellular nitrogen compound metabolic process GO:0034641 290 0.584
regulation of biosynthetic process GO:0009889 250 0.578
nucleobase containing compound biosynthetic process GO:0034654 205 0.575
embryonic eye morphogenesis GO:0048048 30 0.521
cellular macromolecule biosynthetic process GO:0034645 224 0.501
cell surface receptor signaling pathway GO:0007166 325 0.494
nucleic acid metabolic process GO:0090304 244 0.493
formation of primary germ layer GO:0001704 62 0.492
nucleic acid templated transcription GO:0097659 181 0.474
regulation of nucleic acid templated transcription GO:1903506 213 0.474
regulation of cellular metabolic process GO:0031323 320 0.474
regulation of rna biosynthetic process GO:2001141 213 0.472
heterocycle biosynthetic process GO:0018130 215 0.400
convergent extension GO:0060026 118 0.397
regulation of rna metabolic process GO:0051252 224 0.382
macromolecule biosynthetic process GO:0009059 227 0.372
regulation of nitrogen compound metabolic process GO:0051171 251 0.362
heart development GO:0007507 313 0.358
transcription dna templated GO:0006351 181 0.352
chordate embryonic development GO:0043009 271 0.351
regulation of signaling GO:0023051 235 0.351
regulation of cellular biosynthetic process GO:0031326 245 0.349
regulation of mesodermal cell fate specification GO:0042661 9 0.345
regulation of macromolecule metabolic process GO:0060255 317 0.306
rna metabolic process GO:0016070 219 0.304
digestive system development GO:0055123 289 0.295
negative regulation of cellular process GO:0048523 283 0.294
embryonic heart tube morphogenesis GO:0003143 108 0.289
cellular nitrogen compound biosynthetic process GO:0044271 218 0.267
regionalization GO:0003002 274 0.265
response to chemical GO:0042221 320 0.256
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.255
single organism metabolic process GO:0044710 217 0.251
dorsal ventral pattern formation GO:0009953 125 0.240
mesodermal cell fate specification GO:0007501 12 0.236
regulation of multicellular organismal development GO:2000026 223 0.232
digestive tract morphogenesis GO:0048546 231 0.232
gastrulation GO:0007369 208 0.226
convergent extension involved in gastrulation GO:0060027 71 0.223
positive regulation of metabolic process GO:0009893 108 0.217
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.210
determination of dorsal ventral asymmetry GO:0048262 34 0.210
rna biosynthetic process GO:0032774 181 0.205
gene expression GO:0010467 252 0.197
regulation of wnt signaling pathway involved in heart development GO:0003307 2 0.194
regulation of gene expression GO:0010468 265 0.186
organonitrogen compound biosynthetic process GO:1901566 47 0.183
negative regulation of biological process GO:0048519 304 0.178
determination of left right symmetry GO:0007368 179 0.177
synaptic transmission GO:0007268 35 0.171
embryonic organ morphogenesis GO:0048562 274 0.165
mesoderm morphogenesis GO:0048332 51 0.164
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.163
spemann organizer formation GO:0060061 10 0.162
enzyme linked receptor protein signaling pathway GO:0007167 106 0.160
nitrogen compound metabolic process GO:0006807 319 0.156
vasculature development GO:0001944 278 0.151
heart morphogenesis GO:0003007 156 0.149
organonitrogen compound metabolic process GO:1901564 74 0.149
mitotic nuclear division GO:0007067 18 0.148
negative regulation of mesodermal cell fate specification GO:0042662 3 0.146
positive regulation of biological process GO:0048518 253 0.138
eye development GO:0001654 277 0.132
epithelial tube morphogenesis GO:0060562 148 0.131
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.128
aging GO:0007568 2 0.126
retina development in camera type eye GO:0060041 146 0.124
determination of bilateral symmetry GO:0009855 204 0.117
regulation of transcription dna templated GO:0006355 213 0.116
regulation of multicellular organismal process GO:0051239 277 0.113
eye photoreceptor cell differentiation GO:0001754 45 0.112
specification of symmetry GO:0009799 204 0.111
gall bladder development GO:0061010 1 0.107
blood vessel development GO:0001568 246 0.105
cellular localization GO:0051641 97 0.103
regulation of oocyte development GO:0060281 3 0.101
transcription from rna polymerase ii promoter GO:0006366 80 0.099
optic placode formation GO:0001743 4 0.096
embryonic organ development GO:0048568 381 0.096
camera type eye development GO:0043010 222 0.095
somite development GO:0061053 96 0.095
regulation of cell communication GO:0010646 232 0.094
negative regulation of gene expression GO:0010629 65 0.092
regulation of signal transduction GO:0009966 225 0.091
negative regulation of mitosis GO:0045839 3 0.090
cell motility GO:0048870 244 0.089
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.088
cell migration GO:0016477 237 0.084
protein metabolic process GO:0019538 183 0.084
appendage development GO:0048736 80 0.083
pectoral fin development GO:0033339 50 0.082
appendage morphogenesis GO:0035107 56 0.082
regulation of molecular function GO:0065009 70 0.077
morphogenesis of an epithelium GO:0002009 333 0.075
endodermal cell fate specification GO:0001714 17 0.074
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.071
specification of organ position GO:0010159 3 0.069
carbohydrate derivative metabolic process GO:1901135 61 0.069
determination of ventral identity GO:0048264 21 0.068
defense response GO:0006952 47 0.067
embryonic limb morphogenesis GO:0030326 2 0.065
single organism localization GO:1902578 225 0.065
negative regulation of response to stimulus GO:0048585 104 0.064
regulation of cell cycle GO:0051726 52 0.064
regulation of biological quality GO:0065008 263 0.063
small molecule metabolic process GO:0044281 77 0.063
mesodermal cell fate commitment GO:0001710 14 0.061
negative regulation of macromolecule metabolic process GO:0010605 76 0.060
locomotion GO:0040011 313 0.058
cell migration involved in gastrulation GO:0042074 79 0.058
negative regulation of nucleic acid templated transcription GO:1903507 45 0.058
connective tissue development GO:0061448 99 0.057
determination of left right asymmetry in nervous system GO:0035545 4 0.057
mesoderm development GO:0007498 88 0.057
bmp signaling pathway involved in heart development GO:0061312 15 0.056
sensory organ development GO:0007423 393 0.056
regulation of system process GO:0044057 40 0.055
regulation of cell motility GO:2000145 46 0.055
striated muscle cell differentiation GO:0051146 129 0.055
negative regulation of metabolic process GO:0009892 86 0.055
phosphorus metabolic process GO:0006793 109 0.054
mesodermal cell differentiation GO:0048333 21 0.053
multi organism process GO:0051704 134 0.053
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.053
regulation of bmp signaling pathway GO:0030510 39 0.052
determination of heart left right asymmetry GO:0061371 117 0.051
axial mesodermal cell fate specification GO:0048327 3 0.051
canonical wnt signaling pathway GO:0060070 48 0.050
regulation of cellular amine metabolic process GO:0033238 0 0.050
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.049
positive regulation of response to stimulus GO:0048584 80 0.049
response to stress GO:0006950 263 0.049
growth GO:0040007 174 0.049
muscle cell differentiation GO:0042692 139 0.049
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.049
cellular response to organic substance GO:0071310 105 0.049
determination of dorsal identity GO:0048263 13 0.048
regulation of response to stimulus GO:0048583 269 0.047
cellular response to chemical stimulus GO:0070887 157 0.047
negative regulation of cellular biosynthetic process GO:0031327 55 0.047
regulation of apoptotic process GO:0042981 98 0.047
anterior posterior pattern specification GO:0009952 152 0.047
proepicardium development GO:0003342 4 0.047
determination of left right asymmetry in diencephalon GO:0035462 4 0.046
negative regulation of cell communication GO:0010648 96 0.046
regulation of protein metabolic process GO:0051246 56 0.046
oocyte differentiation GO:0009994 14 0.046
cellular component movement GO:0006928 335 0.045
system process GO:0003008 185 0.044
axial mesoderm formation GO:0048320 4 0.044
retinal rod cell development GO:0046548 4 0.044
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.043
endoderm development GO:0007492 49 0.043
positive regulation of jnk cascade GO:0046330 3 0.043
regulation of transcription involved in cell fate commitment GO:0060850 1 0.042
neural retina development GO:0003407 49 0.041
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.040
generation of neurons GO:0048699 385 0.040
regulation of organ morphogenesis GO:2000027 35 0.040
negative regulation of signal transduction GO:0009968 94 0.040
notochord development GO:0030903 54 0.040
positive regulation of programmed cell death GO:0043068 29 0.040
carboxylic acid metabolic process GO:0019752 22 0.039
embryonic camera type eye development GO:0031076 29 0.039
developmental induction GO:0031128 10 0.039
negative regulation of wnt signaling pathway involved in heart development GO:0003308 2 0.039
negative regulation of nuclear division GO:0051784 3 0.038
regulation of endodermal cell fate specification GO:0042663 15 0.038
negative regulation of rna metabolic process GO:0051253 48 0.037
cardiac muscle cell differentiation GO:0055007 30 0.037
transport GO:0006810 220 0.036
negative regulation of bmp signaling pathway GO:0030514 13 0.036
establishment of localization GO:0051234 244 0.036
neuron development GO:0048666 262 0.035
negative regulation of cellular metabolic process GO:0031324 77 0.035
negative regulation of cell death GO:0060548 60 0.035
cellular protein metabolic process GO:0044267 129 0.033
bmp signaling pathway involved in heart jogging GO:0003303 14 0.033
digestive tract development GO:0048565 265 0.033
vasculogenesis GO:0001570 41 0.033
regulation of protein complex assembly GO:0043254 3 0.032
positive regulation of rna metabolic process GO:0051254 59 0.032
immune system process GO:0002376 241 0.032
multicellular organism reproduction GO:0032504 35 0.032
b cell mediated immunity GO:0019724 3 0.032
atrioventricular valve formation GO:0003190 3 0.031
negative regulation of protein phosphorylation GO:0001933 4 0.031
regulation of programmed cell death GO:0043067 101 0.031
larval development GO:0002164 2 0.030
photoreceptor cell fate commitment GO:0046552 1 0.030
optic placode formation involved in camera type eye formation GO:0046619 3 0.030
single organism reproductive process GO:0044702 40 0.029
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.029
regulation of cell differentiation GO:0045595 142 0.029
divalent inorganic cation transport GO:0072511 21 0.028
striated muscle cell development GO:0055002 108 0.028
regulation of cellular ketone metabolic process GO:0010565 7 0.028
positive regulation of signaling GO:0023056 56 0.028
positive regulation of cellular metabolic process GO:0031325 94 0.028
negative regulation of signaling GO:0023057 96 0.028
anterior posterior axis specification GO:0009948 20 0.027
positive regulation of cellular process GO:0048522 201 0.027
cellular ketone metabolic process GO:0042180 11 0.027
negative regulation of mitotic cell cycle GO:0045930 11 0.027
positive regulation of secretion GO:0051047 1 0.027
cell fate specification GO:0001708 68 0.027
protein localization to nucleus GO:0034504 3 0.026
retina layer formation GO:0010842 24 0.026
regulation of cellular protein metabolic process GO:0032268 52 0.026
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.026
negative regulation of rna biosynthetic process GO:1902679 45 0.026
negative regulation of biosynthetic process GO:0009890 55 0.025
regulation of phosphate metabolic process GO:0019220 43 0.025
single organism organelle organization GO:1902589 199 0.025
septum transversum development GO:0003343 4 0.024
peptidyl threonine phosphorylation GO:0018107 1 0.024
organ formation GO:0048645 17 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.024
cellular component biogenesis GO:0044085 178 0.024
dorsal convergence GO:0060030 14 0.023
sensory organ morphogenesis GO:0090596 200 0.023
macromolecule modification GO:0043412 111 0.023
negative regulation of apoptotic process GO:0043066 55 0.023
cellular protein modification process GO:0006464 100 0.023
striated muscle tissue development GO:0014706 110 0.022
tissue regeneration GO:0042246 74 0.022
cell cell signaling GO:0007267 52 0.022
negative regulation of protein complex assembly GO:0031333 1 0.022
embryonic heart tube development GO:0035050 133 0.022
negative regulation of molecular function GO:0044092 23 0.022
death GO:0016265 121 0.022
response to external stimulus GO:0009605 264 0.022
meiotic cell cycle process GO:1903046 3 0.021
stem cell proliferation GO:0072089 4 0.021
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.021
catechol containing compound metabolic process GO:0009712 2 0.021
maintenance of location GO:0051235 4 0.021
neurotransmitter transport GO:0006836 2 0.021
regulation of binding GO:0051098 3 0.021
cellular carbohydrate metabolic process GO:0044262 4 0.020
regulation of heart morphogenesis GO:2000826 17 0.020
specification of organ identity GO:0010092 2 0.020
negative regulation of catabolic process GO:0009895 3 0.020
mesenchymal cell development GO:0014031 78 0.020
positive regulation of catabolic process GO:0009896 4 0.020
regulation of developmental process GO:0050793 247 0.020
single organism biosynthetic process GO:0044711 71 0.020
cell projection organization GO:0030030 284 0.019
regulation of reproductive process GO:2000241 4 0.019
inner ear development GO:0048839 126 0.019
amine metabolic process GO:0009308 2 0.019
regulation of endodermal cell differentiation GO:1903224 15 0.019
peptidyl threonine modification GO:0018210 1 0.019
developmental growth GO:0048589 166 0.019
regulation of gastrulation GO:0010470 24 0.019
negative regulation of gastrulation GO:2000542 11 0.019
renal system development GO:0072001 94 0.018
diencephalon development GO:0021536 58 0.018
regulation of embryonic development GO:0045995 47 0.018
hematopoietic stem cell differentiation GO:0060218 20 0.017
cell proliferation involved in heart morphogenesis GO:0061323 2 0.017
positive regulation of biosynthetic process GO:0009891 68 0.017
negative regulation of transcription dna templated GO:0045892 45 0.017
taxis GO:0042330 109 0.017
oocyte maturation GO:0001556 4 0.017
divalent metal ion transport GO:0070838 20 0.017
somatic muscle development GO:0007525 4 0.017
negative regulation of multicellular organismal process GO:0051241 69 0.017
kidney development GO:0001822 92 0.017
cell cycle GO:0007049 93 0.017
endodermal cell differentiation GO:0035987 19 0.017
regulation of response to stress GO:0080134 36 0.016
cardiogenic plate morphogenesis GO:0003142 1 0.016
regulation of stem cell differentiation GO:2000736 4 0.016
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
organic acid metabolic process GO:0006082 31 0.016
odontogenesis of dentin containing tooth GO:0042475 1 0.016
regulation of cellular response to growth factor stimulus GO:0090287 35 0.016
ameboidal type cell migration GO:0001667 143 0.016
muscle tissue development GO:0060537 110 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.016
organelle organization GO:0006996 227 0.016
neuron projection development GO:0031175 180 0.016
multi organism reproductive process GO:0044703 36 0.016
wnt signaling pathway GO:0016055 80 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.015
programmed cell death GO:0012501 119 0.015
apoptotic process GO:0006915 116 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
pharyngeal muscle development GO:0043282 4 0.015
negative regulation of cell differentiation GO:0045596 46 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.015
primary neural tube formation GO:0014020 1 0.015
organic substance transport GO:0071702 58 0.015
regulation of cell fate commitment GO:0010453 22 0.015
heart looping GO:0001947 94 0.015
somitogenesis GO:0001756 87 0.015
morphogenesis of an epithelial fold GO:0060571 1 0.014
muscle structure development GO:0061061 196 0.014
heart field specification GO:0003128 1 0.014
negative regulation of striated muscle tissue development GO:0045843 2 0.014
response to alcohol GO:0097305 14 0.014
spinal cord anterior posterior patterning GO:0021512 1 0.014
camera type eye photoreceptor cell differentiation GO:0060219 19 0.014
protein complex biogenesis GO:0070271 30 0.014
nerve development GO:0021675 45 0.014
skeletal system development GO:0001501 181 0.014
cell fate commitment GO:0045165 99 0.013
intermediate mesoderm development GO:0048389 2 0.013
fin regeneration GO:0031101 51 0.013
cellular amine metabolic process GO:0044106 2 0.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.013
negative regulation of kinase activity GO:0033673 4 0.013
hepatic duct development GO:0061011 2 0.013
regulation of cell death GO:0010941 103 0.013
liposaccharide metabolic process GO:1903509 8 0.013
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.013
lateral mesoderm development GO:0048368 23 0.013
cation homeostasis GO:0055080 33 0.013
blood vessel morphogenesis GO:0048514 216 0.013
muscle fiber development GO:0048747 52 0.013
microtubule polymerization GO:0046785 2 0.013
negative regulation of cell cycle GO:0045786 14 0.013
multicellular organismal reproductive process GO:0048609 35 0.012
reproduction GO:0000003 40 0.012
mesenchyme development GO:0060485 127 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
metal ion homeostasis GO:0055065 26 0.012
endoderm formation GO:0001706 29 0.012
negative regulation of cell development GO:0010721 26 0.012
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 5 0.012
positive regulation of rna biosynthetic process GO:1902680 57 0.012
gamete generation GO:0007276 33 0.012
meiotic nuclear division GO:0007126 4 0.012
heart valve formation GO:0003188 4 0.012
gland development GO:0048732 143 0.012
axis specification GO:0009798 43 0.012
negative regulation of embryonic development GO:0045992 11 0.012
camera type eye morphogenesis GO:0048593 108 0.012
cellular response to oxygen containing compound GO:1901701 20 0.012
cellular amino acid metabolic process GO:0006520 7 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
regulation of locomotion GO:0040012 55 0.011
pronephros morphogenesis GO:0072114 14 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
photoreceptor cell differentiation GO:0046530 55 0.011
brain development GO:0007420 293 0.011
response to bacterium GO:0009617 58 0.011
regulation of cardiac muscle cell differentiation GO:2000725 1 0.011
cell morphogenesis GO:0000902 289 0.011
negative regulation of multi organism process GO:0043901 3 0.011
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.011
retinal pigment epithelium development GO:0003406 8 0.011
homeostatic process GO:0042592 142 0.011
nuclear import GO:0051170 3 0.011
positive regulation of signal transduction GO:0009967 56 0.011
multicellular organism growth GO:0035264 4 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
epidermal cell fate specification GO:0009957 4 0.011
post anal tail morphogenesis GO:0036342 19 0.011
cardiac chamber morphogenesis GO:0003206 12 0.010
spindle assembly GO:0051225 2 0.010
aorta morphogenesis GO:0035909 3 0.010
notochord morphogenesis GO:0048570 17 0.010
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.010
negative regulation of oocyte development GO:0060283 2 0.010
negative regulation of wnt signaling pathway GO:0030178 30 0.010
positive regulation of transport GO:0051050 2 0.010
macromolecule localization GO:0033036 54 0.010
cellular protein complex assembly GO:0043623 19 0.010
regulation of response to external stimulus GO:0032101 31 0.010
spemann organizer formation at the embryonic shield GO:0060063 2 0.010
cardiocyte differentiation GO:0035051 44 0.010

vox disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.055
bone disease DOID:0080001 0 0.055
disease of anatomical entity DOID:7 0 0.055
dysostosis DOID:1934 0 0.055
musculoskeletal system disease DOID:17 0 0.055
connective tissue disease DOID:65 0 0.055