Danio rerio

61 known processes

robo3

roundabout homolog 3

(Aliases: cb503)

robo3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron projection guidance GO:0097485 86 0.995
central nervous system neuron differentiation GO:0021953 74 0.991
Zebrafish
anterior posterior axon guidance GO:0033564 5 0.990
Zebrafish
retinal ganglion cell axon guidance GO:0031290 35 0.988
Zebrafish
response to external stimulus GO:0009605 264 0.975
axon midline choice point recognition GO:0016199 4 0.974
central nervous system development GO:0007417 387 0.972
Zebrafish Fly
response to organic substance GO:0010033 153 0.953
regulation of macromolecule metabolic process GO:0060255 317 0.953
regulation of axon guidance GO:1902667 8 0.945
Zebrafish
establishment of localization GO:0051234 244 0.924
axon guidance GO:0007411 86 0.922
larval development GO:0002164 2 0.918
positive regulation of signal transduction GO:0009967 56 0.914
Zebrafish
embryonic organ development GO:0048568 381 0.906
Fly
forebrain development GO:0030900 96 0.903
cardioblast migration GO:0003260 7 0.901
Zebrafish
cellular macromolecule metabolic process GO:0044260 391 0.901
regulation of axonogenesis GO:0050770 32 0.900
Zebrafish
chemotaxis GO:0006935 104 0.879
cell morphogenesis involved in differentiation GO:0000904 195 0.874
response to chemical GO:0042221 320 0.873
heterocycle biosynthetic process GO:0018130 215 0.866
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.844
regulation of rna metabolic process GO:0051252 224 0.831
axon choice point recognition GO:0016198 5 0.829
regulation of neuron differentiation GO:0045664 56 0.821
Zebrafish Fly
brain morphogenesis GO:0048854 18 0.818
Fly
signal transduction GO:0007165 455 0.799
Zebrafish Worm Fly
negative regulation of gene expression GO:0010629 65 0.793
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.784
Zebrafish
negative regulation of axon guidance GO:1902668 1 0.780
Zebrafish
neuron differentiation GO:0030182 353 0.768
positive regulation of cellular process GO:0048522 201 0.754
Zebrafish Fly
axonogenesis GO:0007409 152 0.754
cardiac cell fate commitment GO:0060911 1 0.752
Fly
heart formation GO:0060914 13 0.747
Zebrafish
forebrain generation of neurons GO:0021872 14 0.742
diencephalon development GO:0021536 58 0.739
response to abiotic stimulus GO:0009628 122 0.720
appendage development GO:0048736 80 0.719
nucleobase containing compound biosynthetic process GO:0034654 205 0.709
telencephalon development GO:0021537 14 0.700
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.697
commissural neuron axon guidance GO:0071679 3 0.692
positive regulation of rac protein signal transduction GO:0035022 1 0.687
Zebrafish
gene expression GO:0010467 252 0.678
sensory organ development GO:0007423 393 0.678
regulation of gene expression GO:0010468 265 0.678
specification of symmetry GO:0009799 204 0.672
cell projection morphogenesis GO:0048858 244 0.659
negative regulation of macromolecule metabolic process GO:0010605 76 0.657
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.651
ear development GO:0043583 127 0.649
forebrain regionalization GO:0021871 4 0.649
gamete generation GO:0007276 33 0.641
positive regulation of cell death GO:0010942 29 0.640
determination of left right symmetry GO:0007368 179 0.628
regulation of dendrite development GO:0050773 3 0.625
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.624
response to stress GO:0006950 263 0.623
regulation of axon extension involved in axon guidance GO:0048841 6 0.621
Zebrafish
sensory organ morphogenesis GO:0090596 200 0.613
central nervous system neuron development GO:0021954 29 0.613
Zebrafish
heterocycle metabolic process GO:0046483 290 0.607
regulation of binding GO:0051098 3 0.598
regulation of signal transduction GO:0009966 225 0.597
Zebrafish
myotube differentiation GO:0014902 45 0.597
nephron tubule morphogenesis GO:0072078 1 0.596
negative regulation of response to stimulus GO:0048585 104 0.595
Zebrafish
aromatic compound biosynthetic process GO:0019438 217 0.592
cellular nitrogen compound biosynthetic process GO:0044271 218 0.565
cellular ketone metabolic process GO:0042180 11 0.563
negative regulation of signal transduction GO:0009968 94 0.557
regulation of biological quality GO:0065008 263 0.551
Zebrafish Fly
nucleic acid metabolic process GO:0090304 244 0.543
endothelial cell migration GO:0043542 19 0.541
Zebrafish
regulation of transcription dna templated GO:0006355 213 0.540
startle response GO:0001964 4 0.539
Fly
forebrain neuron development GO:0021884 7 0.535
organic cyclic compound metabolic process GO:1901360 301 0.533
cell surface receptor signaling pathway GO:0007166 325 0.529
Fly
regulation of cell proliferation GO:0042127 37 0.526
regulation of molecular function GO:0065009 70 0.526
muscle cell development GO:0055001 115 0.524
axon extension GO:0048675 45 0.516
transport GO:0006810 220 0.510
cellular aromatic compound metabolic process GO:0006725 295 0.509
response to light stimulus GO:0009416 46 0.500
determination of bilateral symmetry GO:0009855 204 0.498
cell morphogenesis GO:0000902 289 0.497
positive regulation of neurogenesis GO:0050769 24 0.492
camera type eye development GO:0043010 222 0.491
regulation of protein binding GO:0043393 3 0.484
cellular component movement GO:0006928 335 0.478
heart development GO:0007507 313 0.477
Zebrafish Fly
regulation of metabolic process GO:0019222 359 0.474
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.472
Zebrafish
heart looping GO:0001947 94 0.465
single organism organelle organization GO:1902589 199 0.464
regulation of rna biosynthetic process GO:2001141 213 0.458
regulation of nitrogen compound metabolic process GO:0051171 251 0.456
regulation of developmental growth GO:0048638 38 0.455
Zebrafish
regulation of nucleic acid templated transcription GO:1903506 213 0.444
negative regulation of chemotaxis GO:0050922 4 0.440
Zebrafish
cell motility GO:0048870 244 0.438
Zebrafish Mouse Worm Fly
small molecule metabolic process GO:0044281 77 0.436
regulation of cellular biosynthetic process GO:0031326 245 0.433
regulation of multicellular organism growth GO:0040014 4 0.431
neuron projection morphogenesis GO:0048812 161 0.430
motor neuron axon guidance GO:0008045 23 0.424
Fly
negative regulation of biological process GO:0048519 304 0.422
Zebrafish
reproductive process GO:0022414 40 0.421
Fly
cell growth GO:0016049 57 0.419
response to fibroblast growth factor GO:0071774 22 0.416
morphogenesis of an epithelium GO:0002009 333 0.410
Zebrafish
biological adhesion GO:0022610 40 0.408
Zebrafish Fly
axon development GO:0061564 166 0.407
inner ear development GO:0048839 126 0.403
establishment of protein localization to organelle GO:0072594 4 0.400
single organism reproductive process GO:0044702 40 0.400
Fly
cell migration to the midline involved in heart development GO:0003318 12 0.400
Zebrafish
macromolecule biosynthetic process GO:0009059 227 0.398
forebrain cell migration GO:0021885 1 0.396
neuron development GO:0048666 262 0.389
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.388
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.388
forebrain neuron fate commitment GO:0021877 1 0.377
muscle structure development GO:0061061 196 0.376
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.376
regulation of dendrite morphogenesis GO:0048814 3 0.372
single organism metabolic process GO:0044710 217 0.359
limbic system development GO:0021761 16 0.357
neuron migration GO:0001764 22 0.356
Mouse Worm Fly
forebrain anterior posterior pattern specification GO:0021797 3 0.351
oxoacid metabolic process GO:0043436 31 0.351
proximal distal pattern formation GO:0009954 1 0.348
muscle cell differentiation GO:0042692 139 0.347
neuron projection extension GO:1990138 45 0.342
intracellular signal transduction GO:0035556 85 0.339
Zebrafish
skeletal muscle fiber development GO:0048741 35 0.336
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.335
tissue regeneration GO:0042246 74 0.333
negative regulation of cell communication GO:0010648 96 0.329
synapse organization GO:0050808 21 0.328
Zebrafish
generation of neurons GO:0048699 385 0.328
heart morphogenesis GO:0003007 156 0.323
Zebrafish Fly
regulation of cell development GO:0060284 100 0.323
Zebrafish Fly
cell migration involved in gastrulation GO:0042074 79 0.321
negative regulation of metabolic process GO:0009892 86 0.318
negative regulation of cellular process GO:0048523 283 0.316
Zebrafish
organelle organization GO:0006996 227 0.316
positive regulation of neuron projection development GO:0010976 9 0.316
epithalamus development GO:0021538 10 0.312
cellular response to chemical stimulus GO:0070887 157 0.312
Mouse
positive regulation of cell cycle GO:0045787 3 0.310
organic cyclic compound biosynthetic process GO:1901362 223 0.309
striated muscle cell differentiation GO:0051146 129 0.307
eye development GO:0001654 277 0.304
striated muscle cell development GO:0055002 108 0.303
anatomical structure homeostasis GO:0060249 36 0.300
Fly
response to endogenous stimulus GO:0009719 83 0.299
regulation of biosynthetic process GO:0009889 250 0.295
organic substance biosynthetic process GO:1901576 289 0.291
regulation of response to stimulus GO:0048583 269 0.285
Zebrafish
embryonic heart tube morphogenesis GO:0003143 108 0.283
taxis GO:0042330 109 0.279
multicellular organismal reproductive process GO:0048609 35 0.279
protein import GO:0017038 3 0.277
camera type eye morphogenesis GO:0048593 108 0.275
negative regulation of nervous system development GO:0051961 22 0.273
Zebrafish
negative regulation of signaling GO:0023057 96 0.272
protein metabolic process GO:0019538 183 0.272
single organism nuclear import GO:1902593 3 0.271
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.269
segmentation GO:0035282 97 0.269
gastrulation GO:0007369 208 0.267
axon extension involved in axon guidance GO:0048846 10 0.266
Zebrafish
regulation of establishment of protein localization GO:0070201 4 0.264
reproductive structure development GO:0048608 5 0.263
Fly
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.261
nucleocytoplasmic transport GO:0006913 4 0.258
regulation of locomotion GO:0040012 55 0.253
Zebrafish Fly
protein import into nucleus GO:0006606 3 0.252
regulation of nervous system development GO:0051960 90 0.250
Zebrafish Fly
positive regulation of apoptotic process GO:0043065 29 0.250
dorsal ventral pattern formation GO:0009953 125 0.247
regulation of primary metabolic process GO:0080090 311 0.245
head development GO:0060322 303 0.239
Fly
gabaergic neuron differentiation GO:0097154 2 0.238
nucleic acid templated transcription GO:0097659 181 0.237
response to growth factor GO:0070848 39 0.237
neuron projection development GO:0031175 180 0.235
response to radiation GO:0009314 51 0.234
forebrain neuron differentiation GO:0021879 14 0.231
meiotic nuclear division GO:0007126 4 0.230
embryonic heart tube development GO:0035050 133 0.228
Fly
protein targeting to nucleus GO:0044744 3 0.228
digestive system development GO:0055123 289 0.228
cell projection organization GO:0030030 284 0.225
embryo development ending in birth or egg hatching GO:0009792 271 0.223
locomotion GO:0040011 313 0.222
carbohydrate metabolic process GO:0005975 12 0.220
negative regulation of locomotion GO:0040013 18 0.219
Zebrafish
locomotory behavior GO:0007626 34 0.219
Fly
response to organic cyclic compound GO:0014070 51 0.218
embryonic organ morphogenesis GO:0048562 274 0.217
glucose homeostasis GO:0042593 1 0.217
regulation of glial cell differentiation GO:0045685 4 0.216
single organism localization GO:1902578 225 0.216
kidney development GO:0001822 92 0.213
nitrogen compound metabolic process GO:0006807 319 0.212
cell part morphogenesis GO:0032990 246 0.210
regulation of neuron projection development GO:0010975 40 0.209
Zebrafish Fly
cellular biosynthetic process GO:0044249 286 0.208
cell migration GO:0016477 237 0.205
Zebrafish Mouse Worm Fly
regulation of multicellular organismal development GO:2000026 223 0.204
Zebrafish Fly
response to lipid GO:0033993 60 0.204
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.203
astrocyte differentiation GO:0048708 1 0.203
regulation of transferase activity GO:0051338 16 0.202
nephron morphogenesis GO:0072028 2 0.202
regulation of cellular metabolic process GO:0031323 320 0.200
central nervous system neuron axonogenesis GO:0021955 18 0.200
Zebrafish
forebrain morphogenesis GO:0048853 6 0.199
primary neural tube formation GO:0014020 1 0.198
regulation of intracellular protein transport GO:0033157 3 0.197
biosynthetic process GO:0009058 294 0.192
spinal cord development GO:0021510 46 0.192
skeletal muscle organ development GO:0060538 78 0.192
neuroblast proliferation GO:0007405 2 0.192
brain development GO:0007420 293 0.192
Fly
negative regulation of synapse assembly GO:0051964 2 0.190
Zebrafish
regulation of cellular component organization GO:0051128 86 0.188
Zebrafish Fly
positive regulation of signaling GO:0023056 56 0.188
Zebrafish
digestive tract development GO:0048565 265 0.187
positive regulation of cell matrix adhesion GO:0001954 1 0.186
Zebrafish
convergent extension involved in organogenesis GO:0060029 10 0.186
Zebrafish
regulation of cell growth GO:0001558 29 0.185
Zebrafish
regulation of apoptotic process GO:0042981 98 0.183
regulation of nucleocytoplasmic transport GO:0046822 2 0.180
regulation of protein ubiquitination GO:0031396 3 0.180
positive regulation of biological process GO:0048518 253 0.179
Zebrafish Fly
urogenital system development GO:0001655 97 0.178
regulation of axon extension GO:0030516 24 0.177
Zebrafish
cellular nitrogen compound metabolic process GO:0034641 290 0.175
regulation of signaling GO:0023051 235 0.172
Zebrafish
cellular amino acid metabolic process GO:0006520 7 0.172
developmental growth involved in morphogenesis GO:0060560 86 0.168
nephron development GO:0072006 31 0.167
blood vessel morphogenesis GO:0048514 216 0.166
Zebrafish
regulation of cell cycle GO:0051726 52 0.166
axonal defasciculation GO:0007414 2 0.165
endocardial progenitor cell migration to the midline involved in heart field formation GO:0003262 4 0.163
Zebrafish
regulation of anatomical structure morphogenesis GO:0022603 130 0.159
Zebrafish
cell cycle process GO:0022402 53 0.158
regulation of protein localization to nucleus GO:1900180 2 0.157
regulation of localization GO:0032879 104 0.155
Zebrafish Fly
multi organism process GO:0051704 134 0.154
hair cell differentiation GO:0035315 32 0.152
nucleobase containing compound metabolic process GO:0006139 274 0.151
response to oxygen containing compound GO:1901700 55 0.151
development of primary female sexual characteristics GO:0046545 4 0.150
olfactory lobe development GO:0021988 4 0.149
response to steroid hormone GO:0048545 35 0.146
modification dependent macromolecule catabolic process GO:0043632 3 0.146
homeostatic process GO:0042592 142 0.142
Fly
regulation of cellular ketone metabolic process GO:0010565 7 0.142
cellular amine metabolic process GO:0044106 2 0.140
multicellular organism growth GO:0035264 4 0.140
negative regulation of axon extension GO:0030517 7 0.138
Zebrafish
regulation of skeletal muscle fiber development GO:0048742 2 0.138
apoptotic process GO:0006915 116 0.138
programmed cell death GO:0012501 119 0.137
positive regulation of molecular function GO:0044093 33 0.137
somitogenesis GO:0001756 87 0.135
regulation of cell cell adhesion GO:0022407 13 0.135
Fly
negative regulation of biosynthetic process GO:0009890 55 0.131
transcription dna templated GO:0006351 181 0.131
regulation of cell matrix adhesion GO:0001952 1 0.130
Zebrafish
regionalization GO:0003002 274 0.129
myotube cell development GO:0014904 35 0.129
sexual reproduction GO:0019953 36 0.129
embryonic pattern specification GO:0009880 44 0.129
skeletal system morphogenesis GO:0048705 102 0.128
positive regulation of programmed cell death GO:0043068 29 0.127
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.127
muscle fiber development GO:0048747 52 0.126
negative regulation of rna biosynthetic process GO:1902679 45 0.125
regulation of oligodendrocyte differentiation GO:0048713 1 0.125
negative regulation of axonogenesis GO:0050771 7 0.124
Zebrafish
cellular component assembly involved in morphogenesis GO:0010927 107 0.123
protein localization to nucleus GO:0034504 3 0.122
regulation of cell motility GO:2000145 46 0.120
Zebrafish Fly
negative regulation of cellular biosynthetic process GO:0031327 55 0.120
cell migration involved in heart formation GO:0060974 10 0.120
Zebrafish
regulation of protein transport GO:0051223 3 0.120
developmental growth GO:0048589 166 0.119
intracellular transport GO:0046907 32 0.119
organic acid metabolic process GO:0006082 31 0.118
axon regeneration GO:0031103 14 0.117
dendrite development GO:0016358 9 0.117
Fly
detection of mechanical stimulus involved in sensory perception GO:0050974 11 0.116
determination of heart left right asymmetry GO:0061371 117 0.116
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.115
Zebrafish
amine metabolic process GO:0009308 2 0.113
cellular response to endogenous stimulus GO:0071495 68 0.112
nuclear import GO:0051170 3 0.111
cell death GO:0008219 121 0.111
cell proliferation in dorsal spinal cord GO:0010456 2 0.111
rna biosynthetic process GO:0032774 181 0.110
olfactory placode morphogenesis GO:0071699 7 0.107
rna metabolic process GO:0016070 219 0.106
death GO:0016265 121 0.105
nuclear division GO:0000280 23 0.104
cellular carbohydrate metabolic process GO:0044262 4 0.103
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 6 0.102
negative regulation of response to cytokine stimulus GO:0060761 2 0.101
cellular response to organic substance GO:0071310 105 0.100
embryonic camera type eye development GO:0031076 29 0.100
renal tubule morphogenesis GO:0061333 1 0.099
epithelial to mesenchymal transition GO:0001837 21 0.098
epithelial cell differentiation GO:0030855 116 0.097
photoreceptor cell differentiation GO:0046530 55 0.096
sensory neuron axon guidance GO:0097374 3 0.096
striated muscle tissue development GO:0014706 110 0.096
regulation of neurogenesis GO:0050767 87 0.095
Zebrafish Fly
peripheral nervous system neuron differentiation GO:0048934 28 0.092
regulation of epithelial cell proliferation GO:0050678 3 0.091
convergent extension involved in gastrulation GO:0060027 71 0.091
retina development in camera type eye GO:0060041 146 0.090
semicircular canal development GO:0060872 24 0.090
regulation of cellular protein metabolic process GO:0032268 52 0.090
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.090
dendrite guidance GO:0070983 0 0.090
Fly
protein localization to plasma membrane GO:0072659 1 0.088
mitotic cell cycle process GO:1903047 48 0.087
negative regulation of kinase activity GO:0033673 4 0.087
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.087
regulation of synapse organization GO:0050807 3 0.086
Zebrafish
epithelial cell morphogenesis GO:0003382 2 0.085
cell projection assembly GO:0030031 64 0.085
Zebrafish
positive regulation of metabolic process GO:0009893 108 0.085
limb development GO:0060173 8 0.085
bmp signaling pathway GO:0030509 52 0.085
single organism carbohydrate metabolic process GO:0044723 12 0.085
regulation of cell communication GO:0010646 232 0.084
Zebrafish
phagocytosis GO:0006909 3 0.084
negative regulation of nucleic acid templated transcription GO:1903507 45 0.084
positive regulation of response to stimulus GO:0048584 80 0.084
Zebrafish
intracellular receptor signaling pathway GO:0030522 30 0.083
cell proliferation in hindbrain GO:0021534 4 0.082
wnt signaling pathway GO:0016055 80 0.082
macromolecular complex subunit organization GO:0043933 74 0.082
olfactory bulb development GO:0021772 4 0.081
regulation of cellular response to growth factor stimulus GO:0090287 35 0.081
regulation of wnt signaling pathway GO:0030111 53 0.080
appendage morphogenesis GO:0035107 56 0.080
regulation of phosphorus metabolic process GO:0051174 43 0.079
epithelial tube morphogenesis GO:0060562 148 0.079
positive regulation of cellular biosynthetic process GO:0031328 68 0.077
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.076
carboxylic acid metabolic process GO:0019752 22 0.076
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.076
Zebrafish
cilium assembly GO:0042384 58 0.076
cellular response to nutrient levels GO:0031669 2 0.075
cellular response to growth factor stimulus GO:0071363 39 0.074
positive regulation of glial cell differentiation GO:0045687 1 0.074
cellular macromolecule biosynthetic process GO:0034645 224 0.074
fin development GO:0033333 77 0.074
cellular protein metabolic process GO:0044267 129 0.074
regulation of kinase activity GO:0043549 15 0.074
regulation of developmental process GO:0050793 247 0.073
Zebrafish Fly
regulation of protein targeting GO:1903533 2 0.072
system process GO:0003008 185 0.072
Fly
pectoral fin morphogenesis GO:0035138 29 0.072
olfactory placode development GO:0071698 12 0.072
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.072
heart field specification GO:0003128 1 0.072
neuroblast fate determination GO:0007400 1 0.071
carbohydrate derivative biosynthetic process GO:1901137 43 0.070
multi organism reproductive process GO:0044703 36 0.070
somatic stem cell maintenance GO:0035019 1 0.070
determination of dorsal ventral asymmetry GO:0048262 34 0.070
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.070
stem cell proliferation GO:0072089 4 0.069
regulation of cellular amino acid metabolic process GO:0006521 0 0.069
myofibril assembly GO:0030239 48 0.069
embryonic limb morphogenesis GO:0030326 2 0.069
limb bud formation GO:0060174 2 0.068
negative regulation of cell proliferation GO:0008285 8 0.067
regulation of cell cycle process GO:0010564 20 0.067
mesenchymal cell differentiation GO:0048762 87 0.067
aging GO:0007568 2 0.066
cell adhesion GO:0007155 40 0.066
Zebrafish Fly
protein complex subunit organization GO:0071822 46 0.066
tube morphogenesis GO:0035239 349 0.066
cell proliferation in forebrain GO:0021846 3 0.066
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.066
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.065
hypothalamus development GO:0021854 14 0.065
cranial nerve morphogenesis GO:0021602 15 0.064
embryonic neurocranium morphogenesis GO:0048702 15 0.064
positive regulation of cellular metabolic process GO:0031325 94 0.064
regulation of meiotic cell cycle GO:0051445 1 0.063
negative regulation of cell migration GO:0030336 17 0.063
positive regulation of nervous system development GO:0051962 25 0.063
extracellular structure organization GO:0043062 27 0.063
embryonic skeletal system morphogenesis GO:0048704 93 0.063
positive regulation of cell communication GO:0010647 56 0.063
Zebrafish
positive regulation of biosynthetic process GO:0009891 68 0.062
limb morphogenesis GO:0035108 7 0.062
cell cycle g1 s phase transition GO:0044843 1 0.062
multicellular organismal homeostasis GO:0048871 29 0.062
growth GO:0040007 174 0.061
modification dependent protein catabolic process GO:0019941 3 0.061
multicellular organism reproduction GO:0032504 35 0.060
innervation GO:0060384 3 0.060
establishment of cell polarity GO:0030010 18 0.060
regulation of cytoplasmic transport GO:1903649 4 0.060
macromolecular complex assembly GO:0065003 35 0.060
stem cell differentiation GO:0048863 117 0.060
Fly
positive regulation of nucleic acid templated transcription GO:1903508 57 0.059
head morphogenesis GO:0060323 8 0.059
positive regulation of neuron differentiation GO:0045666 12 0.059
negative regulation of transcription dna templated GO:0045892 45 0.058
regulation of canonical wnt signaling pathway GO:0060828 34 0.058
cell cycle GO:0007049 93 0.057
response to corticosteroid GO:0031960 1 0.057
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.056
embryonic camera type eye morphogenesis GO:0048596 19 0.056
nuclear transport GO:0051169 4 0.056
macromolecule localization GO:0033036 54 0.056
mitotic cell cycle GO:0000278 64 0.055
regulation of cell size GO:0008361 29 0.055
Zebrafish
vasculature development GO:0001944 278 0.055
Zebrafish
organelle fission GO:0048285 23 0.055
photoreceptor cell fate commitment GO:0046552 1 0.055
cell proliferation GO:0008283 80 0.055
regulation of catalytic activity GO:0050790 55 0.054
establishment of mitotic spindle orientation GO:0000132 10 0.054
epithelial cell development GO:0002064 42 0.054
cellular component biogenesis GO:0044085 178 0.054
Zebrafish
cognition GO:0050890 1 0.053
heart valve formation GO:0003188 4 0.053
cellular protein modification process GO:0006464 100 0.053
neuroblast differentiation GO:0014016 1 0.053
gland development GO:0048732 143 0.052
Fly
cellular response to extracellular stimulus GO:0031668 2 0.052
cell substrate adhesion GO:0031589 4 0.052
Zebrafish
hypothalamus cell differentiation GO:0021979 4 0.052
sex differentiation GO:0007548 5 0.052
Fly
nephron epithelium morphogenesis GO:0072088 1 0.051
single organism biosynthetic process GO:0044711 71 0.051
biomineral tissue development GO:0031214 13 0.051
cellular response to organic cyclic compound GO:0071407 38 0.051
angiogenesis GO:0001525 158 0.051
Zebrafish
neural precursor cell proliferation GO:0061351 20 0.051
regulation of protein metabolic process GO:0051246 56 0.050
female gonad development GO:0008585 4 0.050
regulation of organelle organization GO:0033043 29 0.050
regulation of neural precursor cell proliferation GO:2000177 3 0.050
peripheral nervous system development GO:0007422 55 0.049
regulation of skeletal muscle tissue development GO:0048641 4 0.049
detection of mechanical stimulus GO:0050982 11 0.049
regulation of inner ear receptor cell differentiation GO:2000980 1 0.049
muscle organ development GO:0007517 101 0.049
positive regulation of gliogenesis GO:0014015 2 0.049
heart valve morphogenesis GO:0003179 8 0.048
negative regulation of behavior GO:0048521 6 0.048
Zebrafish
digestive tract morphogenesis GO:0048546 231 0.048
response to wounding GO:0009611 116 0.048
lens development in camera type eye GO:0002088 22 0.047
outflow tract morphogenesis GO:0003151 1 0.047
Fly
establishment of localization in cell GO:0051649 77 0.047
endomembrane system organization GO:0010256 13 0.047
positive regulation of gene expression GO:0010628 71 0.047
positive regulation of catabolic process GO:0009896 4 0.047
glial cell differentiation GO:0010001 42 0.046
negative regulation of neurogenesis GO:0050768 20 0.046
Zebrafish
positive regulation of axonogenesis GO:0050772 6 0.046
regulation of cellular component size GO:0032535 30 0.046
Zebrafish
skeletal system development GO:0001501 181 0.046
diencephalon morphogenesis GO:0048852 5 0.046
regulation of cell death GO:0010941 103 0.045
negative regulation of catenin import into nucleus GO:0035414 2 0.045
regeneration GO:0031099 91 0.045
regulation of cellular amine metabolic process GO:0033238 0 0.045
negative regulation of endothelial cell migration GO:0010596 1 0.045
positive regulation of rna metabolic process GO:0051254 59 0.044
dendrite morphogenesis GO:0048813 5 0.044
Fly
regulation of cell substrate adhesion GO:0010810 1 0.044
Zebrafish
response to glucocorticoid GO:0051384 1 0.043
phosphate containing compound metabolic process GO:0006796 108 0.043
neuromuscular process controlling balance GO:0050885 3 0.043
tube formation GO:0035148 25 0.043
cellular component morphogenesis GO:0032989 336 0.043

robo3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.069
disease of cellular proliferation DOID:14566 0 0.069