Danio rerio

0 known processes

aplp

amyloid beta (A4) precursor-like protein

(Aliases: im:7153266,wu:fj55h01)

aplp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.143
gtp catabolic process GO:0006184 2 0.052
aging GO:0007568 2 0.051
signal transduction GO:0007165 455 0.046
generation of neurons GO:0048699 385 0.046
guanosine containing compound metabolic process GO:1901068 4 0.045
neuron differentiation GO:0030182 353 0.044
gtp metabolic process GO:0046039 4 0.041
regulation of metabolic process GO:0019222 359 0.040
cell migration GO:0016477 237 0.040
meiotic nuclear division GO:0007126 4 0.040
regulation of reproductive process GO:2000241 4 0.040
fertilization GO:0009566 3 0.039
guanosine containing compound catabolic process GO:1901069 2 0.039
stem cell proliferation GO:0072089 4 0.038
cellular aromatic compound metabolic process GO:0006725 295 0.038
negative regulation of biological process GO:0048519 304 0.038
nitrogen compound metabolic process GO:0006807 319 0.038
locomotion GO:0040011 313 0.037
maintenance of location GO:0051235 4 0.037
synaptic growth at neuromuscular junction GO:0051124 2 0.036
regulation of gtp catabolic process GO:0033124 2 0.036
regulation of multicellular organismal process GO:0051239 277 0.035
regulation of multicellular organism growth GO:0040014 4 0.035
negative regulation of cellular process GO:0048523 283 0.035
cellular macromolecule metabolic process GO:0044260 391 0.035
phagocytosis GO:0006909 3 0.034
stem cell division GO:0017145 1 0.034
regulation of response to stimulus GO:0048583 269 0.034
cytokinesis GO:0000910 3 0.034
regulation of cytoplasmic transport GO:1903649 4 0.034
regulation of nucleotide catabolic process GO:0030811 2 0.034
establishment of localization GO:0051234 244 0.034
positive regulation of transport GO:0051050 2 0.033
regulation of biological quality GO:0065008 263 0.033
regulation of purine nucleotide catabolic process GO:0033121 2 0.033
embryonic organ morphogenesis GO:0048562 274 0.033
regulation of nucleoside metabolic process GO:0009118 2 0.033
response to chemical GO:0042221 320 0.032
organic cyclic compound metabolic process GO:1901360 301 0.032
brain development GO:0007420 293 0.031
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.031
positive regulation of cell cycle GO:0045787 3 0.030
regulation of protein complex assembly GO:0043254 3 0.030
heterocycle metabolic process GO:0046483 290 0.030
cellular component movement GO:0006928 335 0.030
regulation of synapse organization GO:0050807 3 0.030
embryo development ending in birth or egg hatching GO:0009792 271 0.029
hematopoietic or lymphoid organ development GO:0048534 191 0.029
multicellular organism growth GO:0035264 4 0.029
cell motility GO:0048870 244 0.029
immune system process GO:0002376 241 0.029
response to external stimulus GO:0009605 264 0.029
cellular nitrogen compound metabolic process GO:0034641 290 0.028
rna metabolic process GO:0016070 219 0.028
organelle organization GO:0006996 227 0.028
gene expression GO:0010467 252 0.028
cell part morphogenesis GO:0032990 246 0.028
nucleocytoplasmic transport GO:0006913 4 0.027
nucleobase containing compound metabolic process GO:0006139 274 0.027
stem cell maintenance GO:0019827 4 0.027
nuclear transport GO:0051169 4 0.027
central nervous system development GO:0007417 387 0.026
regulation of nitrogen compound metabolic process GO:0051171 251 0.026
single organism organelle organization GO:1902589 199 0.026
single organism transport GO:0044765 206 0.026
membrane fusion GO:0061025 2 0.026
regulation of signal transduction GO:0009966 225 0.026
positive regulation of biological process GO:0048518 253 0.026
regulation of biosynthetic process GO:0009889 250 0.026
digestive system development GO:0055123 289 0.026
cellular component morphogenesis GO:0032989 336 0.025
cognition GO:0050890 1 0.025
cellular component disassembly GO:0022411 1 0.025
regulation of protein transport GO:0051223 3 0.025
growth GO:0040007 174 0.025
digestive tract development GO:0048565 265 0.025
lipid storage GO:0019915 1 0.025
regulation of cellular metabolic process GO:0031323 320 0.024
protein polymerization GO:0051258 4 0.024
tube morphogenesis GO:0035239 349 0.024
positive regulation of catabolic process GO:0009896 4 0.024
single organism localization GO:1902578 225 0.024
eye development GO:0001654 277 0.023
positive regulation of cellular process GO:0048522 201 0.023
multi organism process GO:0051704 134 0.023
sensory organ development GO:0007423 393 0.023
positive regulation of cellular component biogenesis GO:0044089 3 0.023
cell projection organization GO:0030030 284 0.023
protein localization to plasma membrane GO:0072659 1 0.023
developmental growth GO:0048589 166 0.023
hemopoiesis GO:0030097 183 0.023
regulation of gtpase activity GO:0043087 2 0.023
cell surface receptor signaling pathway GO:0007166 325 0.023
regionalization GO:0003002 274 0.023
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.023
system process GO:0003008 185 0.023
neuron development GO:0048666 262 0.023
regulation of developmental process GO:0050793 247 0.023
digestive tract morphogenesis GO:0048546 231 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.022
cellular protein catabolic process GO:0044257 4 0.022
heart development GO:0007507 313 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
neuroblast proliferation GO:0007405 2 0.022
regulation of signaling GO:0023051 235 0.022
cell morphogenesis GO:0000902 289 0.022
regulation of gene expression GO:0010468 265 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
regulation of macromolecule metabolic process GO:0060255 317 0.021
small molecule metabolic process GO:0044281 77 0.021
phagocytosis engulfment GO:0006911 1 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
morphogenesis of an epithelium GO:0002009 333 0.021
membrane invagination GO:0010324 1 0.021
regulation of metal ion transport GO:0010959 4 0.021
regulation of cell communication GO:0010646 232 0.021
nuclear import GO:0051170 3 0.021
single fertilization GO:0007338 3 0.021
amine metabolic process GO:0009308 2 0.021
protein import GO:0017038 3 0.021
transport GO:0006810 220 0.020
regulation of meiotic cell cycle GO:0051445 1 0.020
axonogenesis GO:0007409 152 0.020
single organism metabolic process GO:0044710 217 0.020
nucleic acid templated transcription GO:0097659 181 0.020
meiotic cell cycle process GO:1903046 3 0.020
cellular response to extracellular stimulus GO:0031668 2 0.019
establishment of protein localization to plasma membrane GO:0090002 1 0.019
cytoskeleton dependent cytokinesis GO:0061640 3 0.019
cellular component biogenesis GO:0044085 178 0.019
single organism membrane fusion GO:0044801 2 0.019
tissue remodeling GO:0048771 4 0.019
chordate embryonic development GO:0043009 271 0.019
head development GO:0060322 303 0.018
g protein coupled receptor signaling pathway GO:0007186 74 0.018
cellular response to external stimulus GO:0071496 2 0.018
synaptic vesicle transport GO:0048489 1 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
ubiquitin dependent protein catabolic process GO:0006511 3 0.018
organic substance biosynthetic process GO:1901576 289 0.018
nucleic acid metabolic process GO:0090304 244 0.018
embryonic organ development GO:0048568 381 0.018
adult behavior GO:0030534 2 0.018
positive regulation of gtp catabolic process GO:0033126 1 0.018
homeostatic process GO:0042592 142 0.018
regulation of cytokine production GO:0001817 3 0.018
immune system development GO:0002520 191 0.018
negative regulation of catabolic process GO:0009895 3 0.017
gastrulation GO:0007369 208 0.017
rna localization GO:0006403 4 0.017
cellular biosynthetic process GO:0044249 286 0.017
neurotransmitter secretion GO:0007269 2 0.017
cellular component assembly GO:0022607 170 0.017
cell cycle g1 s phase transition GO:0044843 1 0.017
proteasomal protein catabolic process GO:0010498 2 0.017
regulation of cell activation GO:0050865 1 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
intracellular signal transduction GO:0035556 85 0.017
neuron projection morphogenesis GO:0048812 161 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
single organism nuclear import GO:1902593 3 0.017
regulation of synapse assembly GO:0051963 3 0.017
transcription dna templated GO:0006351 181 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
mitochondrion organization GO:0007005 4 0.017
cellular amine metabolic process GO:0044106 2 0.017
regulation of exocytosis GO:0017157 1 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
oxoacid metabolic process GO:0043436 31 0.017
response to carbohydrate GO:0009743 3 0.017
regulation of multicellular organismal development GO:2000026 223 0.017
protein localization to nucleus GO:0034504 3 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
compound eye development GO:0048749 2 0.016
blood vessel development GO:0001568 246 0.016
female meiotic division GO:0007143 2 0.016
regulation of primary metabolic process GO:0080090 311 0.016
organelle fusion GO:0048284 3 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.016
regulation of binding GO:0051098 3 0.016
regulation of rna biosynthetic process GO:2001141 213 0.016
response to stress GO:0006950 263 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.016
exocytosis GO:0006887 1 0.016
specification of symmetry GO:0009799 204 0.016
organonitrogen compound metabolic process GO:1901564 74 0.016
localization of cell GO:0051674 244 0.016
rna biosynthetic process GO:0032774 181 0.016
inner ear development GO:0048839 126 0.016
sensory organ morphogenesis GO:0090596 200 0.016
nuclear export GO:0051168 1 0.016
neuron projection development GO:0031175 180 0.016
macromolecule biosynthetic process GO:0009059 227 0.015
ear development GO:0043583 127 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
protein targeting to nucleus GO:0044744 3 0.015
macromolecular complex disassembly GO:0032984 1 0.015
skeletal system development GO:0001501 181 0.015
endosomal transport GO:0016197 2 0.015
sensory perception of chemical stimulus GO:0007606 3 0.015
regulation of rho protein signal transduction GO:0035023 2 0.015
cellular response to nutrient levels GO:0031669 2 0.015
axon development GO:0061564 166 0.015
protein import into nucleus GO:0006606 3 0.015
organic acid metabolic process GO:0006082 31 0.015
determination of left right symmetry GO:0007368 179 0.015
regulation of synaptic plasticity GO:0048167 1 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
programmed cell death GO:0012501 119 0.015
positive regulation of gtpase activity GO:0043547 1 0.015
neuron neuron synaptic transmission GO:0007270 1 0.015
actin filament polymerization GO:0030041 2 0.015
sequestering of metal ion GO:0051238 3 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.014
establishment of synaptic vesicle localization GO:0097480 1 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.014
camera type eye development GO:0043010 222 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
cellular ketone metabolic process GO:0042180 11 0.014
lateral line system development GO:0048925 76 0.014
response to monosaccharide GO:0034284 3 0.014
determination of bilateral symmetry GO:0009855 204 0.014
biosynthetic process GO:0009058 294 0.014
regulation of rna metabolic process GO:0051252 224 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
regulation of cell differentiation GO:0045595 142 0.014
neurotransmitter transport GO:0006836 2 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
cytoplasm organization GO:0007028 4 0.013
regulation of protein polymerization GO:0032271 2 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
regulation of muscle contraction GO:0006937 3 0.013
antimicrobial humoral response GO:0019730 2 0.013
protein metabolic process GO:0019538 183 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
regulation of cell shape GO:0008360 1 0.013
regulation of cellular component organization GO:0051128 86 0.013
cellular response to starvation GO:0009267 1 0.013
ear morphogenesis GO:0042471 64 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
regulation of dna replication GO:0006275 3 0.013
developmental growth involved in morphogenesis GO:0060560 86 0.013
spermatid development GO:0007286 2 0.013
response to organic substance GO:0010033 153 0.013
blood circulation GO:0008015 87 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
vasculature development GO:0001944 278 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.013
sensory system development GO:0048880 76 0.013
positive regulation of secretion GO:0051047 1 0.013
carbohydrate homeostasis GO:0033500 1 0.013
synaptic vesicle localization GO:0097479 1 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
positive regulation of reproductive process GO:2000243 2 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
regulation of molecular function GO:0065009 70 0.012
cell projection morphogenesis GO:0048858 244 0.012
autophagy GO:0006914 4 0.012
negative regulation of cell communication GO:0010648 96 0.012
regulation of protein targeting GO:1903533 2 0.012
negative regulation of protein phosphorylation GO:0001933 4 0.012
regulation of calcium ion transport GO:0051924 2 0.012
negative regulation of defense response GO:0031348 2 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
response to glucose GO:0009749 3 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
cellular response to organic substance GO:0071310 105 0.012
blood vessel morphogenesis GO:0048514 216 0.012
spermatid differentiation GO:0048515 2 0.012
determination of heart left right asymmetry GO:0061371 117 0.012
negative regulation of signal transduction GO:0009968 94 0.012
regulation of transcription dna templated GO:0006355 213 0.012
mesenchyme development GO:0060485 127 0.012
posterior lateral line system development GO:0048915 46 0.012
cellular localization GO:0051641 97 0.012
segmentation GO:0035282 97 0.012
phosphate containing compound metabolic process GO:0006796 108 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
apoptotic process GO:0006915 116 0.011
regulation of neurotransmitter transport GO:0051588 1 0.011
organic cyclic compound biosynthetic process GO:1901362 223 0.011
negative regulation of kinase activity GO:0033673 4 0.011
angiogenesis GO:0001525 158 0.011
regulation of inflammatory response GO:0050727 2 0.011
response to biotic stimulus GO:0009607 97 0.011
anterior posterior pattern specification GO:0009952 152 0.011
regulation of protein binding GO:0043393 3 0.011
regulation of programmed cell death GO:0043067 101 0.011
protein stabilization GO:0050821 2 0.011
protein complex disassembly GO:0043241 1 0.011
axon ensheathment in central nervous system GO:0032291 2 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.011
cell death GO:0008219 121 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
negative regulation of sequestering of calcium ion GO:0051283 4 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
embryonic skeletal system morphogenesis GO:0048704 93 0.011
regulation of locomotion GO:0040012 55 0.011
pancreas development GO:0031016 84 0.011
regulation of mrna processing GO:0050684 3 0.011
neurological system process GO:0050877 62 0.011
retina development in camera type eye GO:0060041 146 0.011
response to hexose GO:0009746 3 0.011
phosphorus metabolic process GO:0006793 109 0.011
heart morphogenesis GO:0003007 156 0.011
negative regulation of developmental process GO:0051093 65 0.011
muscle cell differentiation GO:0042692 139 0.011
regulation of localization GO:0032879 104 0.011
glucose homeostasis GO:0042593 1 0.011
positive regulation of protein polymerization GO:0032273 2 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
positive regulation of cell activation GO:0050867 1 0.011
cell cycle GO:0007049 93 0.010
regulation of protein catabolic process GO:0042176 1 0.010
ras protein signal transduction GO:0007265 7 0.010
myeloid cell differentiation GO:0030099 86 0.010
peptide transport GO:0015833 1 0.010
negative regulation of protein kinase activity GO:0006469 4 0.010
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.010
positive regulation of cellular metabolic process GO:0031325 94 0.010
regulation of embryonic development GO:0045995 47 0.010
regulation of tube size GO:0035150 2 0.010
cellular response to endogenous stimulus GO:0071495 68 0.010
protein modification process GO:0036211 100 0.010
regulation of apoptotic process GO:0042981 98 0.010
negative regulation of protein complex assembly GO:0031333 1 0.010
cell substrate adhesion GO:0031589 4 0.010
mechanosensory lateral line system development GO:0048881 49 0.010
negative regulation of metabolic process GO:0009892 86 0.010
positive regulation of metabolic process GO:0009893 108 0.010
cell growth GO:0016049 57 0.010
developmental cell growth GO:0048588 52 0.010

aplp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
nervous system disease DOID:863 0 0.022