Danio rerio

0 known processes

map3k5

mitogen-activated protein kinase kinase kinase 5

(Aliases: Ask1)

map3k5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.091
aging GO:0007568 2 0.055
cell surface receptor signaling pathway GO:0007166 325 0.054
membrane fusion GO:0061025 2 0.046
organelle fusion GO:0048284 3 0.046
single organism membrane fusion GO:0044801 2 0.045
signal transduction GO:0007165 455 0.042
multicellular organism growth GO:0035264 4 0.036
autophagy GO:0006914 4 0.035
positive regulation of catabolic process GO:0009896 4 0.035
nitrogen compound metabolic process GO:0006807 319 0.035
cell projection morphogenesis GO:0048858 244 0.035
cellular nitrogen compound metabolic process GO:0034641 290 0.034
mitochondrion organization GO:0007005 4 0.034
phagocytosis GO:0006909 3 0.033
regulation of nitrogen compound metabolic process GO:0051171 251 0.033
positive regulation of transport GO:0051050 2 0.032
regulation of multicellular organism growth GO:0040014 4 0.032
organic cyclic compound metabolic process GO:1901360 301 0.031
ribonucleoside monophosphate catabolic process GO:0009158 4 0.030
rna localization GO:0006403 4 0.030
gtp catabolic process GO:0006184 2 0.030
cell part morphogenesis GO:0032990 246 0.030
cellular protein catabolic process GO:0044257 4 0.030
organelle organization GO:0006996 227 0.029
nucleobase containing compound metabolic process GO:0006139 274 0.029
cellular component movement GO:0006928 335 0.029
regulation of metabolic process GO:0019222 359 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
positive regulation of cellular component biogenesis GO:0044089 3 0.028
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.027
cellular component morphogenesis GO:0032989 336 0.027
guanosine containing compound catabolic process GO:1901069 2 0.027
maintenance of location GO:0051235 4 0.027
gtp metabolic process GO:0046039 4 0.027
cellular aromatic compound metabolic process GO:0006725 295 0.027
guanosine containing compound metabolic process GO:1901068 4 0.027
establishment of protein localization to organelle GO:0072594 4 0.026
rna metabolic process GO:0016070 219 0.026
atp catabolic process GO:0006200 4 0.026
amine metabolic process GO:0009308 2 0.026
regulation of response to stimulus GO:0048583 269 0.025
locomotion GO:0040011 313 0.025
single organism metabolic process GO:0044710 217 0.025
neuron development GO:0048666 262 0.025
positive regulation of cell cycle GO:0045787 3 0.025
cellular response to external stimulus GO:0071496 2 0.025
regulation of protein complex assembly GO:0043254 3 0.025
cellular response to nutrient levels GO:0031669 2 0.024
nucleic acid metabolic process GO:0090304 244 0.024
nucleoside monophosphate catabolic process GO:0009125 4 0.024
purine nucleoside monophosphate catabolic process GO:0009128 4 0.024
generation of neurons GO:0048699 385 0.024
response to stress GO:0006950 263 0.023
cellular response to extracellular stimulus GO:0031668 2 0.023
regulation of cytokine production GO:0001817 3 0.023
cell projection organization GO:0030030 284 0.023
cell morphogenesis GO:0000902 289 0.023
small molecule metabolic process GO:0044281 77 0.022
stem cell maintenance GO:0019827 4 0.022
neuron differentiation GO:0030182 353 0.022
embryonic organ development GO:0048568 381 0.022
cellular biosynthetic process GO:0044249 286 0.022
regulation of signaling GO:0023051 235 0.022
regulation of primary metabolic process GO:0080090 311 0.022
establishment of localization GO:0051234 244 0.022
response to chemical GO:0042221 320 0.022
cellular macromolecule metabolic process GO:0044260 391 0.022
regulation of cellular metabolic process GO:0031323 320 0.022
regulation of binding GO:0051098 3 0.022
regulation of gene expression GO:0010468 265 0.022
exocytosis GO:0006887 1 0.022
regulation of synapse organization GO:0050807 3 0.021
regulation of macromolecule metabolic process GO:0060255 317 0.021
organonitrogen compound metabolic process GO:1901564 74 0.021
heterocycle metabolic process GO:0046483 290 0.021
gene expression GO:0010467 252 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
cellular amine metabolic process GO:0044106 2 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.021
protein localization to nucleus GO:0034504 3 0.021
proteasomal protein catabolic process GO:0010498 2 0.021
regulation of purine nucleotide catabolic process GO:0033121 2 0.021
neurotransmitter transport GO:0006836 2 0.021
cognition GO:0050890 1 0.021
positive regulation of protein complex assembly GO:0031334 2 0.021
ubiquitin dependent protein catabolic process GO:0006511 3 0.021
regulation of metal ion transport GO:0010959 4 0.020
endosomal transport GO:0016197 2 0.020
regulation of protein catabolic process GO:0042176 1 0.020
synaptic growth at neuromuscular junction GO:0051124 2 0.020
adult behavior GO:0030534 2 0.020
response to drug GO:0042493 3 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
nucleocytoplasmic transport GO:0006913 4 0.020
cell migration GO:0016477 237 0.020
transport GO:0006810 220 0.020
protein import GO:0017038 3 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
positive regulation of nucleotide catabolic process GO:0030813 1 0.019
regulation of signal transduction GO:0009966 225 0.019
positive regulation of biological process GO:0048518 253 0.019
modification dependent protein catabolic process GO:0019941 3 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
regulation of cell communication GO:0010646 232 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
embryo development ending in birth or egg hatching GO:0009792 271 0.019
organic cyclic compound biosynthetic process GO:1901362 223 0.019
cellular response to starvation GO:0009267 1 0.019
regulation of protein transport GO:0051223 3 0.019
regulation of reproductive process GO:2000241 4 0.019
heterocycle biosynthetic process GO:0018130 215 0.019
negative regulation of cellular process GO:0048523 283 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.018
compound eye development GO:0048749 2 0.018
nuclear transport GO:0051169 4 0.018
organic substance biosynthetic process GO:1901576 289 0.018
sensory organ development GO:0007423 393 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.018
negative regulation of protein kinase activity GO:0006469 4 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
nuclear import GO:0051170 3 0.018
regulation of nucleotide catabolic process GO:0030811 2 0.018
nucleic acid templated transcription GO:0097659 181 0.018
regulation of synaptic plasticity GO:0048167 1 0.018
transcription dna templated GO:0006351 181 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.018
neuron projection morphogenesis GO:0048812 161 0.018
oxoacid metabolic process GO:0043436 31 0.018
negative regulation of biological process GO:0048519 304 0.018
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
lipid storage GO:0019915 1 0.018
cell motility GO:0048870 244 0.017
regulation of biological quality GO:0065008 263 0.017
cellular ketone metabolic process GO:0042180 11 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
phosphorus metabolic process GO:0006793 109 0.017
single organism nuclear import GO:1902593 3 0.017
axon development GO:0061564 166 0.017
single organism organelle organization GO:1902589 199 0.017
digestive tract development GO:0048565 265 0.017
cellular response to light stimulus GO:0071482 4 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
cell substrate adhesion GO:0031589 4 0.017
rna modification GO:0009451 2 0.017
peptidyl serine phosphorylation GO:0018105 1 0.017
protein metabolic process GO:0019538 183 0.017
response to uv GO:0009411 3 0.017
protein targeting to nucleus GO:0044744 3 0.017
biosynthetic process GO:0009058 294 0.017
regulation of cell shape GO:0008360 1 0.017
negative regulation of kinase activity GO:0033673 4 0.016
localization of cell GO:0051674 244 0.016
positive regulation of secretion GO:0051047 1 0.016
protein import into nucleus GO:0006606 3 0.016
single organism localization GO:1902578 225 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
regulation of cell activation GO:0050865 1 0.016
regulation of macromolecule biosynthetic process GO:0010556 225 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
golgi vesicle transport GO:0048193 3 0.016
synaptic vesicle transport GO:0048489 1 0.016
response to external stimulus GO:0009605 264 0.016
synaptic vesicle localization GO:0097479 1 0.015
regulation of biosynthetic process GO:0009889 250 0.015
cell morphogenesis involved in differentiation GO:0000904 195 0.015
cellular component disassembly GO:0022411 1 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
protein dephosphorylation GO:0006470 3 0.015
locomotor rhythm GO:0045475 3 0.015
gastrulation GO:0007369 208 0.015
organic acid metabolic process GO:0006082 31 0.015
stem cell proliferation GO:0072089 4 0.015
macromolecule modification GO:0043412 111 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
protein localization to plasma membrane GO:0072659 1 0.015
tube morphogenesis GO:0035239 349 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
growth GO:0040007 174 0.015
cellular response to radiation GO:0071478 4 0.015
cytokinesis GO:0000910 3 0.015
establishment of synaptic vesicle localization GO:0097480 1 0.015
protein acetylation GO:0006473 2 0.015
rna biosynthetic process GO:0032774 181 0.015
muscle structure development GO:0061061 196 0.015
meiotic nuclear division GO:0007126 4 0.015
response to carbohydrate GO:0009743 3 0.015
regulation of developmental process GO:0050793 247 0.015
cellular macromolecule biosynthetic process GO:0034645 224 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
regulation of transporter activity GO:0032409 2 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
regionalization GO:0003002 274 0.014
neuroblast proliferation GO:0007405 2 0.014
system process GO:0003008 185 0.014
regulation of rna metabolic process GO:0051252 224 0.014
regulation of transcription dna templated GO:0006355 213 0.014
neuron neuron synaptic transmission GO:0007270 1 0.014
peptidyl serine modification GO:0018209 2 0.014
macromolecule biosynthetic process GO:0009059 227 0.014
single organism transport GO:0044765 206 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
regulation of dendrite morphogenesis GO:0048814 3 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
cellular component assembly GO:0022607 170 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
cellular component biogenesis GO:0044085 178 0.014
regulation of synapse assembly GO:0051963 3 0.014
eye development GO:0001654 277 0.014
germ line stem cell maintenance GO:0030718 2 0.014
response to monosaccharide GO:0034284 3 0.014
digestive system development GO:0055123 289 0.014
immune system process GO:0002376 241 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
protein modification process GO:0036211 100 0.014
membrane invagination GO:0010324 1 0.014
spermatid development GO:0007286 2 0.014
secondary metabolic process GO:0019748 3 0.014
tissue remodeling GO:0048771 4 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
spermatid differentiation GO:0048515 2 0.013
cellular protein metabolic process GO:0044267 129 0.013
axonogenesis GO:0007409 152 0.013
cellular nitrogen compound biosynthetic process GO:0044271 218 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
regulation of protein targeting GO:1903533 2 0.013
protein polymerization GO:0051258 4 0.013
cilium morphogenesis GO:0060271 85 0.013
neuron projection development GO:0031175 180 0.013
centrosome organization GO:0051297 1 0.013
cellular amide metabolic process GO:0043603 4 0.013
multi organism cellular process GO:0044764 2 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.013
viral process GO:0016032 1 0.013
regulation of neuronal synaptic plasticity GO:0048168 1 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
meiotic cell cycle process GO:1903046 3 0.013
internal protein amino acid acetylation GO:0006475 2 0.013
chemosensory behavior GO:0007635 1 0.013
hemopoiesis GO:0030097 183 0.013
positive regulation of cellular process GO:0048522 201 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
regulation of gtpase activity GO:0043087 2 0.013
camera type eye development GO:0043010 222 0.013
regulation of calcium ion transport GO:0051924 2 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
digestive tract morphogenesis GO:0048546 231 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
protein polyubiquitination GO:0000209 4 0.012
alcohol biosynthetic process GO:0046165 2 0.012
response to hexose GO:0009746 3 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
protein secretion GO:0009306 1 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
cellular response to biotic stimulus GO:0071216 3 0.012
positive regulation of metabolic process GO:0009893 108 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.012
primary neural tube formation GO:0014020 1 0.012
head development GO:0060322 303 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
response to topologically incorrect protein GO:0035966 2 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
nucleic acid transport GO:0050657 2 0.012
microtubule organizing center organization GO:0031023 1 0.012
developmental growth GO:0048589 166 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.012
regulation of dendrite development GO:0050773 3 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
regulation of autophagy GO:0010506 3 0.012
negative regulation of map kinase activity GO:0043407 2 0.012
interspecies interaction between organisms GO:0044419 4 0.012
post golgi vesicle mediated transport GO:0006892 1 0.012
carbohydrate homeostasis GO:0033500 1 0.012
regulation of cell differentiation GO:0045595 142 0.012
central nervous system development GO:0007417 387 0.012
neuronal action potential GO:0019228 18 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
multi organism process GO:0051704 134 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
regulation of multicellular organismal process GO:0051239 277 0.012
intracellular mrna localization GO:0008298 1 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
intracellular signal transduction GO:0035556 85 0.012
cell matrix adhesion GO:0007160 4 0.012
negative regulation of signaling GO:0023057 96 0.012
phototransduction GO:0007602 2 0.012
neuromuscular synaptic transmission GO:0007274 2 0.011
positive regulation of cytokine production GO:0001819 2 0.011
regulation of organelle assembly GO:1902115 4 0.011
lateral inhibition GO:0046331 1 0.011
muscle cell differentiation GO:0042692 139 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
neurological system process GO:0050877 62 0.011
mitochondrial transport GO:0006839 2 0.011
regulation of protein binding GO:0043393 3 0.011
regulation of organ growth GO:0046620 3 0.011
macroautophagy GO:0016236 1 0.011
hormone secretion GO:0046879 2 0.011
organelle assembly GO:0070925 110 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.011
positive regulation of cell activation GO:0050867 1 0.011
centrosome cycle GO:0007098 1 0.011
leukocyte proliferation GO:0070661 1 0.011
female sex differentiation GO:0046660 4 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
regulation of sequestering of calcium ion GO:0051282 4 0.011
homeostatic process GO:0042592 142 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
ovulation cycle process GO:0022602 2 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
liver development GO:0001889 96 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
sequestering of calcium ion GO:0051208 3 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
regulation of neurotransmitter transport GO:0051588 1 0.011
cellular protein modification process GO:0006464 100 0.011
positive regulation of multi organism process GO:0043902 3 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
negative regulation of signal transduction GO:0009968 94 0.011
sensory organ morphogenesis GO:0090596 200 0.011
b cell activation GO:0042113 2 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
macromolecular complex disassembly GO:0032984 1 0.011
peptidyl threonine modification GO:0018210 1 0.011
response to glucose GO:0009749 3 0.011
regulation of cell substrate adhesion GO:0010810 1 0.011
response to organic substance GO:0010033 153 0.011
erythrocyte homeostasis GO:0034101 55 0.011
tube closure GO:0060606 1 0.011
positive regulation of exocytosis GO:0045921 1 0.010
response to glucocorticoid GO:0051384 1 0.010
immune system development GO:0002520 191 0.010
erk1 and erk2 cascade GO:0070371 4 0.010
regulation of protein localization to nucleus GO:1900180 2 0.010
negative regulation of synapse assembly GO:0051964 2 0.010
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.010
regulation of jak stat cascade GO:0046425 3 0.010
regulation of erk1 and erk2 cascade GO:0070372 4 0.010
adherens junction organization GO:0034332 4 0.010
organism emergence from protective structure GO:0071684 4 0.010
regulation of meiotic cell cycle GO:0051445 1 0.010
somatic muscle development GO:0007525 4 0.010
glucose homeostasis GO:0042593 1 0.010
peptide transport GO:0015833 1 0.010
peptidyl threonine phosphorylation GO:0018107 1 0.010
sequestering of metal ion GO:0051238 3 0.010
regulation of exocytosis GO:0017157 1 0.010
response to hydrogen peroxide GO:0042542 3 0.010
negative regulation of multi organism process GO:0043901 3 0.010
enzyme linked receptor protein signaling pathway GO:0007167 106 0.010
positive regulation of stress activated mapk cascade GO:0032874 3 0.010
negative regulation of sequestering of calcium ion GO:0051283 4 0.010
regulation of protein polymerization GO:0032271 2 0.010
urogenital system development GO:0001655 97 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
negative regulation of metabolic process GO:0009892 86 0.010
negative regulation of protein transport GO:0051224 3 0.010
post embryonic organ development GO:0048569 4 0.010
eye morphogenesis GO:0048592 144 0.010

map3k5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.018
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.013
musculoskeletal system disease DOID:17 0 0.012
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012
disease of cellular proliferation DOID:14566 0 0.012