Danio rerio

29 known processes

nbl1

neuroblastoma, suppression of tumorigenicity 1

(Aliases: dan,zgc:77251,MGC77251)

nbl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ development GO:0007423 393 0.570
ear development GO:0043583 127 0.561
inner ear development GO:0048839 126 0.436
semicircular canal development GO:0060872 24 0.429
cytosolic calcium ion transport GO:0060401 3 0.422
regulation of protein complex assembly GO:0043254 3 0.395
g protein coupled receptor signaling pathway GO:0007186 74 0.289
sequestering of metal ion GO:0051238 3 0.286
regulation of protein polymerization GO:0032271 2 0.273
calcium ion transmembrane transport GO:0070588 13 0.272
oocyte maturation GO:0001556 4 0.207
larval development GO:0002164 2 0.193
light induced release of internally sequestered calcium ion GO:0008377 1 0.193
cellular response to radiation GO:0071478 4 0.192
positive regulation of cellular component biogenesis GO:0044089 3 0.181
positive regulation of transport GO:0051050 2 0.165
calcium ion transport into cytosol GO:0060402 3 0.145
sensory organ morphogenesis GO:0090596 200 0.144
angiogenesis GO:0001525 158 0.134
actin polymerization or depolymerization GO:0008154 2 0.129
blood vessel morphogenesis GO:0048514 216 0.123
cellular response to light stimulus GO:0071482 4 0.121
lipid homeostasis GO:0055088 3 0.117
positive regulation of biological process GO:0048518 253 0.116
positive regulation of protein polymerization GO:0032273 2 0.116
vasculature development GO:0001944 278 0.111
regulation of filopodium assembly GO:0051489 2 0.106
inorganic cation transmembrane transport GO:0098662 50 0.100
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.099
sensory perception of chemical stimulus GO:0007606 3 0.092
sequestering of calcium ion GO:0051208 3 0.091
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.083
signal transduction GO:0007165 455 0.081
cellular response to chemical stimulus GO:0070887 157 0.080
calcium ion homeostasis GO:0055074 19 0.080
cellular transition metal ion homeostasis GO:0046916 3 0.078
actin filament polymerization GO:0030041 2 0.075
digestive tract development GO:0048565 265 0.074
detection of abiotic stimulus GO:0009582 24 0.073
negative regulation of cellular process GO:0048523 283 0.072
response to external stimulus GO:0009605 264 0.072
release of sequestered calcium ion into cytosol GO:0051209 3 0.071
regulation of receptor mediated endocytosis GO:0048259 4 0.070
cation homeostasis GO:0055080 33 0.068
cell projection organization GO:0030030 284 0.068
embryonic organ morphogenesis GO:0048562 274 0.067
generation of neurons GO:0048699 385 0.067
receptor internalization GO:0031623 2 0.066
cellular component biogenesis GO:0044085 178 0.064
rhodopsin mediated signaling pathway GO:0016056 1 0.062
regulation of oocyte development GO:0060281 3 0.060
erythrocyte homeostasis GO:0034101 55 0.057
positive regulation of cellular process GO:0048522 201 0.057
response to chemical GO:0042221 320 0.057
negative regulation of sequestering of calcium ion GO:0051283 4 0.056
aromatic compound biosynthetic process GO:0019438 217 0.055
cellular protein catabolic process GO:0044257 4 0.053
embryonic organ development GO:0048568 381 0.053
brain development GO:0007420 293 0.053
blood vessel development GO:0001568 246 0.050
pancreas development GO:0031016 84 0.049
regulation of reproductive process GO:2000241 4 0.049
eye development GO:0001654 277 0.049
maintenance of location GO:0051235 4 0.049
cellular cation homeostasis GO:0030003 17 0.049
response to light stimulus GO:0009416 46 0.049
protein complex biogenesis GO:0070271 30 0.047
transmembrane transport GO:0055085 120 0.047
positive regulation of catabolic process GO:0009896 4 0.046
oocyte development GO:0048599 14 0.046
cellular component assembly GO:0022607 170 0.045
phototransduction visible light GO:0007603 2 0.045
positive regulation of secretion by cell GO:1903532 1 0.044
ribonucleoside monophosphate catabolic process GO:0009158 4 0.043
axon guidance GO:0007411 86 0.042
divalent inorganic cation transport GO:0072511 21 0.042
regulation of cell projection assembly GO:0060491 4 0.042
regulation of cytoskeleton organization GO:0051493 11 0.042
positive regulation of secretion GO:0051047 1 0.041
positive regulation of protein complex assembly GO:0031334 2 0.041
locomotion GO:0040011 313 0.041
organelle fusion GO:0048284 3 0.040
modification dependent protein catabolic process GO:0019941 3 0.040
adult behavior GO:0030534 2 0.039
cellular respiration GO:0045333 3 0.039
muscle tissue development GO:0060537 110 0.039
heterocycle metabolic process GO:0046483 290 0.039
cellular ion homeostasis GO:0006873 17 0.039
cation transmembrane transport GO:0098655 65 0.038
response to abiotic stimulus GO:0009628 122 0.037
protein polymerization GO:0051258 4 0.037
nucleobase containing compound biosynthetic process GO:0034654 205 0.036
energy reserve metabolic process GO:0006112 2 0.036
metal ion homeostasis GO:0055065 26 0.036
metal ion transport GO:0030001 58 0.035
ubiquitin dependent protein catabolic process GO:0006511 3 0.035
regulation of muscle contraction GO:0006937 3 0.035
cellular component movement GO:0006928 335 0.034
regulation of cellular metabolic process GO:0031323 320 0.034
rhombomere 5 development GO:0021571 4 0.034
negative regulation of biosynthetic process GO:0009890 55 0.034
skeletal muscle tissue development GO:0007519 67 0.034
cognition GO:0050890 1 0.033
muscle contraction GO:0006936 18 0.033
homeostatic process GO:0042592 142 0.032
regulation of metal ion transport GO:0010959 4 0.032
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.032
cellular macromolecule metabolic process GO:0044260 391 0.032
establishment of localization GO:0051234 244 0.032
skeletal muscle organ development GO:0060538 78 0.031
regulation of calcium ion transport GO:0051924 2 0.031
embryonic heart tube morphogenesis GO:0003143 108 0.031
single organism membrane fusion GO:0044801 2 0.031
synaptic growth at neuromuscular junction GO:0051124 2 0.031
renal system process GO:0003014 14 0.031
regulation of signaling GO:0023051 235 0.031
nucleobase containing compound metabolic process GO:0006139 274 0.031
programmed cell death GO:0012501 119 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.030
negative regulation of protein kinase activity GO:0006469 4 0.030
cellular response to hypoxia GO:0071456 1 0.030
chordate embryonic development GO:0043009 271 0.030
regulation of membrane potential GO:0042391 23 0.030
system process GO:0003008 185 0.029
negative regulation of cellular metabolic process GO:0031324 77 0.029
positive regulation of cytoskeleton organization GO:0051495 3 0.029
macromolecule catabolic process GO:0009057 15 0.029
cell surface receptor signaling pathway GO:0007166 325 0.029
nitrogen compound metabolic process GO:0006807 319 0.028
single organism organelle organization GO:1902589 199 0.028
regulation of developmental process GO:0050793 247 0.028
hydrogen peroxide metabolic process GO:0042743 2 0.028
inner ear morphogenesis GO:0042472 63 0.028
regulation of sodium ion transport GO:0002028 2 0.028
regulation of synaptic plasticity GO:0048167 1 0.028
oxidation reduction process GO:0055114 41 0.027
cell death GO:0008219 121 0.027
cellular aromatic compound metabolic process GO:0006725 295 0.027
detection of external stimulus GO:0009581 24 0.027
regulation of gene expression GO:0010468 265 0.027
regulation of chondrocyte differentiation GO:0032330 1 0.027
post embryonic organ development GO:0048569 4 0.027
mitochondrion organization GO:0007005 4 0.027
cellular nitrogen compound metabolic process GO:0034641 290 0.027
cellular localization GO:0051641 97 0.027
heart development GO:0007507 313 0.026
regulation of cell communication GO:0010646 232 0.026
cellular divalent inorganic cation homeostasis GO:0072503 13 0.026
negative regulation of biological process GO:0048519 304 0.026
gene expression GO:0010467 252 0.026
divalent metal ion transport GO:0070838 20 0.026
single organism metabolic process GO:0044710 217 0.025
central nervous system development GO:0007417 387 0.025
neurological system process GO:0050877 62 0.025
cell morphogenesis GO:0000902 289 0.025
ion transmembrane transport GO:0034220 91 0.025
amine metabolic process GO:0009308 2 0.025
detection of light stimulus involved in sensory perception GO:0050962 7 0.025
biosynthetic process GO:0009058 294 0.024
establishment of localization in cell GO:0051649 77 0.024
detection of stimulus GO:0051606 29 0.024
cell fate commitment GO:0045165 99 0.024
cell cell signaling GO:0007267 52 0.024
protein metabolic process GO:0019538 183 0.023
regulation of primary metabolic process GO:0080090 311 0.023
detection of light stimulus involved in visual perception GO:0050908 7 0.023
response to drug GO:0042493 3 0.023
regulation of biological quality GO:0065008 263 0.023
digestive tract mesoderm development GO:0007502 1 0.023
cellular response to decreased oxygen levels GO:0036294 1 0.023
axonogenesis GO:0007409 152 0.022
negative regulation of map kinase activity GO:0043407 2 0.022
compound eye development GO:0048749 2 0.022
sensory perception GO:0007600 39 0.022
skeletal system development GO:0001501 181 0.022
regulation of cellular component size GO:0032535 30 0.022
axon development GO:0061564 166 0.022
tube morphogenesis GO:0035239 349 0.022
cellular response to oxygen levels GO:0071453 1 0.022
regulation of apoptotic process GO:0042981 98 0.021
multicellular organism growth GO:0035264 4 0.021
regulation of multicellular organism growth GO:0040014 4 0.021
growth GO:0040007 174 0.021
rhombomere 6 development GO:0021572 4 0.021
regulation of nucleotide biosynthetic process GO:0030808 15 0.021
determination of left right symmetry GO:0007368 179 0.021
regulation of exocytosis GO:0017157 1 0.021
neuron development GO:0048666 262 0.021
aging GO:0007568 2 0.020
organic substance transport GO:0071702 58 0.020
carbohydrate biosynthetic process GO:0016051 1 0.020
regulation of blood vessel size GO:0050880 2 0.020
peptidyl threonine phosphorylation GO:0018107 1 0.019
nucleic acid metabolic process GO:0090304 244 0.019
regulation of neurotransmitter secretion GO:0046928 1 0.019
regulation of cellular biosynthetic process GO:0031326 245 0.019
regulation of biosynthetic process GO:0009889 250 0.019
negative regulation of cell communication GO:0010648 96 0.019
cellular biosynthetic process GO:0044249 286 0.019
embryonic skeletal system development GO:0048706 97 0.019
macromolecule biosynthetic process GO:0009059 227 0.019
multicellular organismal metabolic process GO:0044236 2 0.019
meiotic cell cycle process GO:1903046 3 0.019
organonitrogen compound metabolic process GO:1901564 74 0.018
cellular component disassembly GO:0022411 1 0.018
negative regulation of signaling GO:0023057 96 0.018
negative regulation of ras protein signal transduction GO:0046580 1 0.018
regulation of receptor internalization GO:0002090 2 0.018
autophagy GO:0006914 4 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
positive regulation of blood circulation GO:1903524 2 0.018
negative regulation of developmental process GO:0051093 65 0.018
regulation of organelle organization GO:0033043 29 0.018
detection of stimulus involved in sensory perception GO:0050906 21 0.017
cellular metal ion homeostasis GO:0006875 16 0.017
heart morphogenesis GO:0003007 156 0.017
negative regulation of protein phosphorylation GO:0001933 4 0.017
negative regulation of macromolecule metabolic process GO:0010605 76 0.017
potassium ion transmembrane transport GO:0071805 10 0.017
tissue remodeling GO:0048771 4 0.017
regulation of dendrite development GO:0050773 3 0.017
positive regulation of cell adhesion GO:0045785 1 0.017
cellular carbohydrate metabolic process GO:0044262 4 0.017
regulation of cell shape GO:0008360 1 0.017
response to stress GO:0006950 263 0.017
transition metal ion homeostasis GO:0055076 5 0.017
negative regulation of metabolic process GO:0009892 86 0.017
digestive tract morphogenesis GO:0048546 231 0.017
regulation of cellular response to growth factor stimulus GO:0090287 35 0.017
regulation of macromolecule metabolic process GO:0060255 317 0.016
response to inorganic substance GO:0010035 38 0.016
intracellular signal transduction GO:0035556 85 0.016
negative regulation of homeostatic process GO:0032845 5 0.016
muscle structure development GO:0061061 196 0.016
morphogenesis of an epithelium GO:0002009 333 0.016
protein heterooligomerization GO:0051291 1 0.016
chondrocyte development GO:0002063 4 0.016
ossification GO:0001503 23 0.016
small molecule catabolic process GO:0044282 3 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
cellular chemical homeostasis GO:0055082 17 0.016
negative regulation of blood circulation GO:1903523 2 0.015
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.015
localization of cell GO:0051674 244 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
chemosensory behavior GO:0007635 1 0.015
single organism transport GO:0044765 206 0.015
regulation of multicellular organismal metabolic process GO:0044246 2 0.015
specification of symmetry GO:0009799 204 0.015
nucleic acid templated transcription GO:0097659 181 0.015
negative regulation of stem cell differentiation GO:2000737 2 0.015
urogenital system development GO:0001655 97 0.015
regulation of multicellular organismal process GO:0051239 277 0.015
developmental growth GO:0048589 166 0.015
protein localization to nucleus GO:0034504 3 0.015
peptidyl serine phosphorylation GO:0018105 1 0.015
organic acid metabolic process GO:0006082 31 0.015
regulation of guanylate cyclase activity GO:0031282 6 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
regulation of localization GO:0032879 104 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
striated muscle tissue development GO:0014706 110 0.015
developmental programmed cell death GO:0010623 4 0.015
small molecule metabolic process GO:0044281 77 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
regulation of synapse assembly GO:0051963 3 0.015
neuron neuron synaptic transmission GO:0007270 1 0.015
regulation of cyclase activity GO:0031279 12 0.014
peptidyl threonine modification GO:0018210 1 0.014
oligodendrocyte differentiation GO:0048709 23 0.014
cellular ketone metabolic process GO:0042180 11 0.014
heterocycle biosynthetic process GO:0018130 215 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
negative regulation of reproductive process GO:2000242 3 0.014
reproductive process GO:0022414 40 0.014
homeostasis of number of cells GO:0048872 62 0.014
monoamine transport GO:0015844 1 0.014
gastrulation GO:0007369 208 0.014
wnt signaling pathway GO:0016055 80 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
regulation of carbohydrate biosynthetic process GO:0043255 1 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.014
stem cell proliferation GO:0072089 4 0.014
phagocytosis GO:0006909 3 0.014
negative regulation of cellular biosynthetic process GO:0031327 55 0.014
regulation of carbohydrate metabolic process GO:0006109 4 0.013
apoptotic process involved in morphogenesis GO:0060561 2 0.013
ion transport GO:0006811 114 0.013
regulation of meiotic cell cycle GO:0051445 1 0.013
regulation of release of sequestered calcium ion into cytosol GO:0051279 1 0.013
neuron projection morphogenesis GO:0048812 161 0.013
inositol lipid mediated signaling GO:0048017 2 0.013
apical junction assembly GO:0043297 1 0.013
carbohydrate derivative biosynthetic process GO:1901137 43 0.013
cell cycle arrest GO:0007050 1 0.013
membrane fusion GO:0061025 2 0.013
regulation of protein transport GO:0051223 3 0.013
otic vesicle morphogenesis GO:0071600 34 0.013
determination of bilateral symmetry GO:0009855 204 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
cell migration GO:0016477 237 0.013
inorganic ion transmembrane transport GO:0098660 57 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
cell fate specification GO:0001708 68 0.013
regulation of mitochondrion organization GO:0010821 1 0.013
cellular component morphogenesis GO:0032989 336 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
ribonucleoside metabolic process GO:0009119 11 0.012
cellular amine metabolic process GO:0044106 2 0.012
death GO:0016265 121 0.012
regulation of metabolic process GO:0019222 359 0.012
macromolecular complex disassembly GO:0032984 1 0.012
regulation of blood circulation GO:1903522 32 0.012
chemical homeostasis GO:0048878 49 0.012
protein stabilization GO:0050821 2 0.012
organic substance biosynthetic process GO:1901576 289 0.012
locus ceruleus development GO:0021703 3 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
otic placode formation GO:0043049 23 0.012
rna biosynthetic process GO:0032774 181 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.012
regulation of signal transduction GO:0009966 225 0.012
gtp catabolic process GO:0006184 2 0.012
heart contraction GO:0060047 71 0.012
sympathetic nervous system development GO:0048485 3 0.012
single organism localization GO:1902578 225 0.012
heart valve formation GO:0003188 4 0.012
proteolysis GO:0006508 38 0.012
positive regulation of heart contraction GO:0045823 2 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
taxis GO:0042330 109 0.012
cell projection assembly GO:0030031 64 0.012
enzyme linked receptor protein signaling pathway GO:0007167 106 0.012
connective tissue development GO:0061448 99 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
regulation of anatomical structure size GO:0090066 33 0.011
intracellular transport GO:0046907 32 0.011
neurotransmitter transport GO:0006836 2 0.011
gland development GO:0048732 143 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
response to monosaccharide GO:0034284 3 0.011
regulation of cell death GO:0010941 103 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.011
positive regulation of nucleotide biosynthetic process GO:0030810 8 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
response to hexose GO:0009746 3 0.011
direct ossification GO:0036072 3 0.011
cellular protein complex assembly GO:0043623 19 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
negative regulation of kinase activity GO:0033673 4 0.011
muscle organ development GO:0007517 101 0.011
regulation of tube size GO:0035150 2 0.011
regulation of response to stimulus GO:0048583 269 0.011
organelle organization GO:0006996 227 0.011
cellular response to external stimulus GO:0071496 2 0.011
generation of precursor metabolites and energy GO:0006091 5 0.011
renal system development GO:0072001 94 0.011
hatching GO:0035188 4 0.011
cell growth GO:0016049 57 0.011
digestive system development GO:0055123 289 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
protein dephosphorylation GO:0006470 3 0.011
stem cell maintenance GO:0019827 4 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
organic cyclic compound metabolic process GO:1901360 301 0.011
protein complex disassembly GO:0043241 1 0.010
positive regulation of metabolic process GO:0009893 108 0.010
anterior posterior pattern specification GO:0009952 152 0.010
head development GO:0060322 303 0.010
regulation of programmed cell death GO:0043067 101 0.010
diterpenoid metabolic process GO:0016101 15 0.010
positive regulation of cgmp biosynthetic process GO:0030828 6 0.010
macromolecular complex subunit organization GO:0043933 74 0.010
regulation of behavior GO:0050795 24 0.010
cellular response to organic substance GO:0071310 105 0.010
response to carbohydrate GO:0009743 3 0.010
regulation of multicellular organismal development GO:2000026 223 0.010
embryonic limb morphogenesis GO:0030326 2 0.010
proteasomal protein catabolic process GO:0010498 2 0.010
neurotransmitter secretion GO:0007269 2 0.010
negative regulation of mitosis GO:0045839 3 0.010
camera type eye development GO:0043010 222 0.010
regulation of dna replication GO:0006275 3 0.010
positive regulation of cell death GO:0010942 29 0.010
cell motility GO:0048870 244 0.010
cellular amino acid metabolic process GO:0006520 7 0.010

nbl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
parkinson s disease DOID:14330 0 0.020
synucleinopathy DOID:0050890 0 0.020
central nervous system disease DOID:331 0 0.020
disease of anatomical entity DOID:7 0 0.020
neurodegenerative disease DOID:1289 0 0.020
nervous system disease DOID:863 0 0.020
disease of metabolism DOID:0014667 0 0.012